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https://www.readbyqxmd.com/read/28651345/prioritizing-quality-measure-concepts-at-the-interface-of-behavioral-and-physical-healthcare
#1
Harold Alan Pincus, Mingjie Li, Deborah M Scharf, Brigitta Spaeth-Rublee, Matthew L Goldman, Parashar P Ramanuj, Erin K Ferenchick
Objective: Integrated healthcare models can increase access to care, improve healthcare quality, and reduce cost for individuals with behavioral and general medical healthcare needs, yet there are few instruments for measuring the quality of integrated care. In this study, we identified and prioritized concepts that can represent the quality of integrated behavioral health and general medical care. Design: We conducted a literature review to identify candidate measure concepts...
June 23, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28651339/formation-of-silica-aggregates-in-sorghum-root-endodermis-is-predetermined-by-cell-wall-architecture-and-development
#2
Milan Soukup, Michal Martinka, Dragana Bosnic, Mária Caplovicová, Rivka Elbaum, Alexander Lux
Background and Aims: Deposition of silica in plant cell walls improves their mechanical properties and helps plants to withstand various stress conditions. Its mechanism is still not understood and silica-cell wall interactions are elusive. The objective of this study was to investigate the effect of silica deposition on the development and structure of sorghum root endodermis and to identify the cell wall components involved in silicification. Methods: Sorghum bicolor seedlings were grown hydroponically with (Si+) or without (Si-) silicon supplementation...
June 22, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28651249/administration-of-the-mitochondrial-permeability-transition-pore-inhibitor-tro40303-prior-to-primary-percutaneous-coronary-intervention-does-not-affect-the-levels-of-pro-inflammatory-cytokines-or-acute-phase-proteins
#3
Noreen Butt, Lena K Bache-Mathiesen, Jan Erik Nordrehaug, Vegard Tuseth, Peter Scott Munk, Vernon Bonarjee, Trygve Sundby Hall, Svend Eggert Jensen, Sigrun Halvorsen, Huseyin Firat, Dan Atar, Alf Inge Larsen
OBJECTIVES: In the MITOCARE study, reperfusion injury was not prevented after administration of the mitochondrial permeability transition pore (mPTP) opening inhibitor, TRO40303, in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). The effects of TRO40303 on pro-inflammatory cytokines and acute-phase proteins were assessed. METHODS: STEMI patients (n = 163, mean age 62 years) with chest pain within 6 h before admission for pPCI were randomized to intravenous bolus of TRO40303 (n = 83) or placebo (n = 80) prior to reperfusion...
June 27, 2017: Cardiology
https://www.readbyqxmd.com/read/28651227/double-cystic-duct-preoperatively-diagnosed-and-successfully-treated-with-laparoscopic-cholecystectomy-a-case-report
#4
Atsushi Fujii, Masatsugu Hiraki, Noriyuki Egawa, Hiroshi Kono, Takao Ide, Junichi Nojiri, Junji Ueda, Hiroyuki Irie, Hirokazu Noshiro
INTRODUCTION: A single gallbladder with a double cystic duct is a very rare finding. In addition, few cases with this rare condition are preoperatively diagnosed. However, the preoperative confirmation or suspicion of this rare condition could facilitate safe laparoscopic cholecystectomy, which is a minimally invasive therapeutic modality for gallbladder disease. We herein present a case of gallstone disease in a patient with a double cystic duct who was preoperatively diagnosed and successfully treated with laparoscopic cholecystectomy...
June 13, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28651217/modeling-in-sewer-transformations-at-catchment-scale-implications-on-drug-consumption-estimates-in-wastewater-based-epidemiology
#5
Ann-Kathrin McCall, Rocco Palmitessa, Frank Blumensaat, Eberhard Morgenroth, Christoph Ort
To which extent illicit drugs are transformed during in-sewer transport, depends on a number of factors: i) substance-specific transformation rates, ii) environmental conditions, iii) point of discharge (location of drug user) and iv) sewer network properties, primarily hydraulic residence time (HRT) and the ratio of biofilm contact area to wastewater volume (A/Veq). Assessing associated uncertainties typically requires numerous simulations. Therefore, we propose a new two-step modeling framework: 1) Quantify hydrodynamic conditions...
May 20, 2017: Water Research
https://www.readbyqxmd.com/read/28651071/an-independent-active-contours-segmentation-framework-for-bone-micro-ct-images
#6
Vasileios Ch Korfiatis, Simone Tassani, George K Matsopoulos
Micro-CT is an imaging technique for small tissues and objects that is gaining increased popularity especially as a pre-clinical application. Nevertheless, there is no well-established micro-CT segmentation method, while typical procedures lack sophistication and frequently require a degree of manual intervention, leading to errors and subjective results. To address these issues, a novel segmentation framework, called Independent Active Contours Segmentation (IACS), is proposed in this paper. The proposed IACS is based on two autonomous modules, namely automatic ROI extraction and IAC Evolution, which segments the ROI image using multiple Active Contours that evolve simultaneously and independently of one another...
June 19, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28651069/automatic-mpst-cut-for-segmentation-of-carpal-bones-from-mr-volumes
#7
Laura Gemme, Sonia Nardotto, Silvana G Dellepiane
In the context of rheumatic diseases, several studies suggest that Magnetic Resonance Imaging (MRI) allows the detection of the three main signs of Rheumatoid Arthritis (RA) at higher sensitivities than available through conventional radiology. The rapid, accurate segmentation of bones is an essential preliminary step for quantitative diagnosis, erosion evaluation, and multi-temporal data fusion. In the present paper, a new, semi-automatic, 3D graph-based segmentation method to extract carpal bone data is proposed...
June 12, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28651031/assessment-of-fall-characteristics-from-depth-sensor-videos
#8
Jennifer J O'Connor, Lorraine J Phillips, Bunmi Folarinde, Gregory L Alexander, Marilyn Rantz
Falls are a major source of death and disability in older adults; little data, however, are available about the etiology of falls in community-dwelling older adults. Sensor systems installed in independent and assisted living residences of 105 older adults participating in an ongoing technology study were programmed to record live videos of probable fall events. Sixty-four fall video segments from 19 individuals were viewed and rated using the Falls Video Assessment Questionnaire. Raters identified that 56% (n = 36) of falls were due to an incorrect shift of body weight and 27% (n = 17) from losing support of an external object, such as an unlocked wheelchair or rolling walker...
July 1, 2017: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/28650958/dynamics-and-impact-of-homologous-recombination-on-the-evolution-of-legionella-pneumophila
#9
Sophia David, Leonor Sánchez-Busó, Simon R Harris, Pekka Marttinen, Christophe Rusniok, Carmen Buchrieser, Timothy G Harrison, Julian Parkhill
Legionella pneumophila is an environmental bacterium and the causative agent of Legionnaires' disease. Previous genomic studies have shown that recombination accounts for a high proportion (>96%) of diversity within several major disease-associated sequence types (STs) of L. pneumophila. This suggests that recombination represents a potentially important force shaping adaptation and virulence. Despite this, little is known about the biological effects of recombination in L. pneumophila, particularly with regards to homologous recombination (whereby genes are replaced with alternative allelic variants)...
June 26, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28650932/incremental-value-of-right-atrial-strain-for-early-diagnosis-of-hemodynamic-deterioration-in-pulmonary-hypertension-a-new-noninvasive-tool-for-a-more-comprehensive-diagnostic-paradigma
#10
Cristina Piccinino, Ailia Giubertoni, Jacopo Zanaboni, Miriam Gravellone, Daniele Sola, Roberta Rosso, Lorena Ferrarotti, Paolo Nicola Marino
AIMS: Increased right atrial size is related to adverse prognosis in pulmonary hypertension. The potential incremental value of right atrial function assessment is still unclear. We tested the relationship between right atrial two-dimensional speckle-tracking echocardiography impairment and hemodynamic, functional and clinical deterioration in patients with pulmonary hypertension. METHODS: We prospectively evaluated 36 patients (27 female, 9 male; mean age 68 ± 13 years) with suspected pulmonary hypertension undergoing right heart catheterization and 16 matched controls...
June 24, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28650931/hypertrophic-restrictive-cardiomyopathy-with-apical-thinning-a-peculiar-case-of-genotype-phenotype-correlation
#11
Pierluigi Lesizza, Marco Merlo, Giancarlo Vitrella, Gianfranco Sinagra
: Hypertrophic cardiomyopathy (HCM) is the most common cardiomyopathy, mainly caused by mutations in genes encoding for sarcomere proteins. Even though many mutations have been recognized to be causative of HCM, specific HCM phenotypes can be rarely predicted by the genotype, possibly as a consequence of the presence of still unknown disease-modifying genes [Maron et al. (2013). Lancet 381:242-55]. In this very peculiar case of HCM hypertrophy localized to left ventricle, mid-wall segments coexisted with a restrictive filling pattern and an apical wall thinning mimicking hypoplasia of left ventricle apex...
June 24, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28650925/quantitative-analysis-of-the-inner-retinal-layer-thicknesses-in-age-related-macular-degeneration-using-corrected-optical-coherence-tomography-segmentation
#12
Ilkay Kilic Muftuoglu, Hema L Ramkumar, Dirk-Uwe Bartsch, Amit Meshi, Raouf Gaber, William R Freeman
PURPOSE: To characterize inner retinal damage in patients with dry age-related macular degeneration (AMD) using high-resolution spectral domain optical coherence tomography images. METHODS: Sixty eyes of 60 patients with AMD were categorized using the Age-Related Eye Disease Study (AREDS) severity scale. Spectral domain optical coherence tomography images of these patients were quantified by manually correcting the segmentation of each retinal layer, including the retinal nerve fiber layer, ganglion cell layer, and inner plexiform layer to ensure accurate delineation of layers...
June 23, 2017: Retina
https://www.readbyqxmd.com/read/28650876/the-role-of-imaging-in-strabismus
#13
Jinali R Patel, Kammi B Gunton
PURPOSE OF REVIEW: To review the most recent literature regarding the clinical experience of imaging modalities in strabismus. RECENT FINDINGS: MRI of extraocular muscles (EOMs) has elucidated the roles of variation in compartmental contraction of EOMs and further evidence of EOM pulley heterotopy in various strabismus patterns, which may contribute to the clinical and surgical management of patients as this mode of imaging becomes more readily available. Ultrasound biomicroscopy (UBM) and anterior-segment optical coherence tomography (AS-OCT) may play a role in determining the location of EOMs which could also aid in devising a preoperative surgical plan, especially in those who have had prior strabismus surgery...
June 24, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28650806/3d-active-contour-segmentation-based-on-sparse-linear-combination-of-training-shapes-scots
#14
M Mehdi Farhangi, Hichem Frigui, Albert Seow, Amir A Amini
SCoTS captures a sparse representation of shapes in an input image through a linear span of previously delineated shapes in a training repository. The model updates shape prior over level set iterations and captures variabilities in shapes by a sparse combination of the training data. The level set evolution is therefore driven by a data term as well as a term capturing valid prior shapes. During evolution, the shape prior influence is adjusted based on shape reconstruction, with the assigned weight determined from the degree of sparsity of the representation...
June 26, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28650800/depth-aware-salient-object-detection-and-segmentation-via-multiscale-discriminative-saliency-fusion-and-bootstrap-learning
#15
Hangke Song, Zhi Liu, Huan Du, Guangling Sun, Olivier Le Meur, Tongwei Ren
This paper proposes a novel depth-aware salient object detection and segmentation framework via multiscale discriminative saliency fusion (MDSF) and bootstrap learning for RGBD images (RGB color images with corresponding Depth maps) and stereoscopic images. By exploiting low-level feature contrasts, mid-level feature weighted factors and high-level location priors, various saliency measures on four classes of features are calculated based on multiscale region segmentation. A random forest regressor is learned to perform the discriminative saliency fusion (DSF) and generate the DSF saliency map at each scale, and DSF saliency maps across multiple scales are combined to produce the MDSF saliency map...
September 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28650706/commentary-on-comparison-of-adjacent-segment-degeneration-after-nonrigid-fixation-system-and-posterior-lumbar-inter-body-fusion-for-single-level-lumbar-disc-herniation-a-new-method-of-mri-analysis-of-lumbar-nucleuspulposus-volumen
#16
Máximo-Alberto Díez-Ulloa
No abstract text is available yet for this article.
June 26, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28650665/understanding-the-oxidative-stability-of-antifouling-polymer-brushes
#17
Yong Du, Jingyao Gao, Tingting Chen, Chao Zhang, Jian Ji, Zhi-Kang Xu
Poly(oligoethylene glycol methacrylate) (POEGMA) and zwitterionic polymer brushes have been widely used for constructing biocompatible or antifouling surfaces, and their oxidative stability is very important to the practical application. Herein, POEGMA, poly(sulfobetaine methacrylate) (PSBMA), poly(2-(methacryloyloxy)ethyl phosphorylcholine) (PMPC), and poly(carboxybetaine methacrylate) (PCBMA) were grafted on quartz crystal microbalance (QCM) chips via surface initiated atom transfer radical polymerization (SI-ATRP)...
June 26, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28650514/automatic-segmentation-of-the-spine-by-means-of-a-probabilistic-atlas-with-a-special-focus-on-ribs-suppression
#18
Silvia Ruiz-España, Juan Domingo, Antonio Díaz-Parra, Esther Dura, Víctor D'Ocón-Alcañiz, Estanislao Arana, David Moratal
PURPOSE: The development of automatic and reliable algorithms for the detection and segmentation of the vertebrae are of great importance prior to any diagnostic task. However, an important problem found to accurately segment the vertebrae is the presence of the ribs in the thoracic region. To overcome this problem, a probabilistic atlas of the spine has been developed dealing with the proximity of other structures, with a special focus on ribs suppression. METHODS: The data sets used consist of Computed Tomography images corresponding to 21 patients suffering from spinal metastases...
June 26, 2017: Medical Physics
https://www.readbyqxmd.com/read/28650342/inflammatory-ly6chi-monocytes-and-their-conversion-to-m2-macrophages-drive-atherosclerosis-regression
#19
Karishma Rahman, Yuliya Vengrenyuk, Stephen A Ramsey, Noemi Rotllan Vila, Natasha M Girgis, Jianhua Liu, Viktoria Gusarova, Jesper Gromada, Ada Weinstock, Kathryn J Moore, P'ng Loke, Edward A Fisher
Atherosclerosis is a chronic inflammatory disease, and developing therapies to promote its regression is an important clinical goal. We previously established that atherosclerosis regression is characterized by an overall decrease in plaque macrophages and enrichment in markers of alternatively activated M2 macrophages. We have now investigated the origin and functional requirement for M2 macrophages in regression in normolipidemic mice that received transplants of atherosclerotic aortic segments. We compared plaque regression in WT normolipidemic recipients and those deficient in chemokine receptors necessary to recruit inflammatory Ly6Chi (Ccr2-/- or Cx3cr1-/-) or patrolling Ly6Clo (Ccr5-/-) monocytes...
June 26, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28650316/the-na-ca-2-k-exchanger-nckx4-is-required-for-efficient-cone-mediated-vision
#20
Frans Vinberg, Tian Wang, Alicia De Maria, Haiqing Zhao, Steven Bassnett, Jeannie Chen, Vladimir J Kefalov
Calcium (Ca(2+)) plays an important role in the function and health of neurons. In vertebrate cone photoreceptors, Ca(2+) controls photoresponse sensitivity, kinetics, and light adaptation. Despite the critical role of Ca(2+) in supporting the function and survival of cones, the mechanism for its extrusion from cone outer segments is not well understood. Here, we show that the Na(+)/Ca(2+), K(+) exchanger NCKX4 is expressed in zebrafish, mouse, and primate cones. Functional analysis of NCKX4-deficient mouse cones revealed that this exchanger is essential for the wide operating range and high temporal resolution of cone-mediated vision...
June 26, 2017: ELife
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