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https://www.readbyqxmd.com/read/28535642/-clinical-effects-of-dynesys-system-and-transfacet-decompression-through-wiltse-approach-in-the-treatment-of-lumbar-degenerative-diseases
#1
K Shang, M J Chen, D G Wang
Objective: To investigate the early clinical effects of Dynesys system and transfacet decompression by Wiltse approach in the treatment of lumbar degenerative diseases. Methods: From January 2010 to December 2013, 48 patients suffering from lumbar degenerative diseases were treated with Dynesys system in addition to transfacet decompression through Wiltse approach.There were 28 males and 20 females with age of (51.8±6.8). The preoperative diagnosis included lumbar spinal stenosis(10 cases); lumber intervertebral disc herniation (38 cases)...
May 23, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28535563/the-effectiveness-and-safety-of-selective-lumbar-decompression-in-diagnostic-doubt-patients-a-retrospective-control-study
#2
Li Xiaochuan, Cheng-Fan Zhong, Jian-Hua Tang, Rong-Wei Liang, Shao-Jian Luo, Chun-Ming Huang
BACKGROUND: Our previous study demonstrated that selective nerve root block (SNRB) can influence decision-making in lumbar surgery by guiding the selection of nerve roots targeted for decompression in diagnostic doubt patients (DDPs). However, further studies were needed to determine whether this selective decompression (SD) procedure would result in similar clinical outcomes and reduce the perioperative parameters and postoperative complications as compared to the non-selective decompression (NSD) procedure...
May 2017: Pain Physician
https://www.readbyqxmd.com/read/28535435/multi-segmental-thoracic-spine-kinematics-measured-dynamically-in-the-young-and-elderly-during-flexion
#3
Dominika Ignasiak, Andrea Rüeger, Stephen J Ferguson
In contrast to the cervical and lumbar region, the normal kinematics of the thoracic spine have not been thoroughly investigated. The aim of this study was to characterize normal multi-segmental continuous motion of the whole thoracolumbar spine, during a flexion maneuver, in young and elderly subjects. Forty-two healthy volunteers were analyzed: 21 young (age=27.00±3.96) and 21 elderly (age=70.1±3.85). Spinal motion was recorded with a motion-capture system and analyzed using a 3rd order polynomial function to approximate spinal curvature throughout the motion sequence...
May 20, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28535395/a-zinc-chloride-doped-adhesive-facilitates-sealing-at-the-dentin-interface-a-confocal-laser-microscopy-study
#4
Manuel Toledano, Raquel Osorio, Estrella Osorio, Inmaculada Cabello, Manuel Toledano-Osorio, Fátima S Aguilera
The aim of this study was to ascertain the effect of Zn-doping of dental adhesives and mechanical load cycling on the micromorphology of the resin-dentin interdiffusion zone (of sound and caries affected dentin). The investigation considered two different Zn-doped adhesive approaches and evaluated the interface using a doubled dye fluorescent technique and a calcium chelator fluorophore under a confocal laser scanning microscopy. Sound and carious dentin-resin interfaces of unloaded specimens were deficiently resin-hybridized, in general...
May 19, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28535355/effect-of-composition-asymmetry-on-the-phase-separation-and-crystallization-in-double-crystalline-binary-polymer-blends-a-dynamic-monte-carlo-simulation-study
#5
Ashok Kumar Dasmahapatra
Polymer blends offer an exciting material for various potential applications due to their tunable properties by varying constituting components and their relative composition. Our simulation results unravel an intrinsic relationship between crystallization behavior and composition asymmetry. We report simulation results for non-isothermal and isothermal crystallization with weak and strong segregation strength to elucidate the composition dependent crystallization behavior. With increasing composition of low melting B-polymer, macrophase separation temperature changes non-monotonically, which is attributed to the non-monotonic change in diffusivity of both the polymers...
May 23, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28535343/tuning-adsorption-duration-to-control-the-diffusion-of-a-nanoparticle-in-adsorbing-polymers
#6
Xuezheng Cao, Holger Merlitz, Chen-Xu Wu
Controlling the nanoparticle (NP) diffusion in polymers is a prerequisite to obtain polymer nanocomposites (PNCs) with desired dynamical and rheological properties, and to achieve targeted delivery of nanomedicine in biological systems. Here we determinate the suppression mechanism of direct NP-polymer attraction to hamper the NP mobility in adsorbing polymers, and then quantify the dependence of the effective viscosity \eta_{eff} felt by the NP on the adsorption duration \tau_{ads} of polymers on the NP, using scaling theory analysis and molecular dynamics (MD) simulations...
May 23, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28535059/room-temperature-inp-inasp-quantum-discs-in-nanowire-infrared-photodetectors
#7
Mohammad Karimi, Vishal Jain, Magnus Heurlin, Ali Nowzari, Laiq Hussain, David Lindgren, Jan Eric Stehr, Irina A Buyanova, Anders Gustafsson, Lars Samuelson, Magnus T Borgström, Håkan Jan Pettersson
The possibility to engineer nanowire heterostructures with large bandgap variations is particularly interesting for technologically important broadband photodetector applications. Here we report on a combined study of design, fabrication and optoelectronic properties of infrared photodetectors comprising 4 million n+-i-n+ InP nanowires periodically ordered in arrays. The nanowires were grown by metal-organic vapor phase epitaxy on InP substrates, with either a single or 20 InAsP quantum discs embedded in the i-segment...
May 23, 2017: Nano Letters
https://www.readbyqxmd.com/read/28534994/amplification-and-the-clinical-significance-of-circulating-cell-free-dna-of-pvt1-in-breast-cancer
#8
Xujing Li, Weijuan Chen, Hui Wang, Qun Wei, Xiaodi Ding, Wentong Li
Duplication in the chromosome 8q24 region is a frequent occurrence in carcinomas. The PVT1 oncogene (PVT1), a long non-coding RNA, is found in this locus. PVT1 amplification is a frequent event in cancers, such as in lymphomas, serous ovarian, colorectal and breast cancers. Ectopic PVT1 expression is related with reduced survival duration in cancer patients. in the present study, we proved that PVT1 is markedly augmented in breast cancer tissues compared with adjacent non-tumorous tissues. Thus, PVT1 is an independent prognostic factor for the survival duration of breast cancer patients...
May 18, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28534858/an-adaptive-orientation-estimation-method-for-magnetic-and-inertial-sensors-in-the-presence-of-magnetic-disturbances
#9
Bingfei Fan, Qingguo Li, Chao Wang, Tao Liu
Magnetic and inertial sensors have been widely used to estimate the orientation of human segments due to their low cost, compact size and light weight. However, the accuracy of the estimated orientation is easily affected by external factors, especially when the sensor is used in an environment with magnetic disturbances. In this paper, we propose an adaptive method to improve the accuracy of orientation estimations in the presence of magnetic disturbances. The method is based on existing gradient descent algorithms, and it is performed prior to sensor fusion algorithms...
May 19, 2017: Sensors
https://www.readbyqxmd.com/read/28534802/organ-location-determination-and-contour-sparse-representation-for-multi-organ-segmentation
#10
Siqi Li, Huiyan Jiang, Yu-Dong Yao, Benqiang Yang
Organ segmentation on computed tomography (CT) images is of great importance in medical diagnoses and treatment. This paper proposes organ location determination and contour sparse representation methods (OLD-CSR) for multiorgan segmentation (liver, kidney, and spleen) on abdomen CT images using an extreme learning machine (ELM) classifier. First, a location determination method is designed to obtain location information of each organ, which is used for coarse segmentation. Second, for coarse-to-fine segmentation, a contour gradient and rate change based feature point extraction method is proposed...
May 17, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28534798/alzheimer-s-disease-diagnosis-using-landmark-based-features-from-longitudinal-structural-mr-images
#11
Jun Zhang, Mingxia Liu, Le An, Yaozong Gao, Dinggang Shen
Structural magnetic resonance imaging (MRI) has been proven to be an effective tool for Alzheimer's disease (AD) diagnosis. While conventional MRI-based AD diagnosis typically uses images acquired at a single time point, a longitudinal study is more sensitive in detecting early pathological changes of AD, making it more favorable for accurate diagnosis. In general, there are two challenges faced in MRI-based diagnosis. First, extracting features from structural MR images requires timeconsuming nonlinear registration and tissue segmentation, whereas the longitudinal study with involvement of more scans further exacerbates the computational costs...
May 16, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28534786/evolutionary-computing-enriched-computer-aided-diagnosis-system-for-diabetic-retinopathy-a-survey
#12
Romany Mansour
The alterations caused due to diabetes mellitus results into significant micro-vasculature that eventually causes diabetic retinopathy (DR) that keeps on increasing as per time and eventually causes complete vision loss. Identifying subtle variations in morphological changes in retinal blood vessels, optic disk, exudates, micro-aneurysms, hemorrhage etc is complicate and requires robust computer aided diagnosis (CAD) system so as to enable earlier and efficient DR diagnosis practices. In majority of the existing CAD systems, the need of functional enhancement has been realized time by time to ensure accurate and time efficient DR...
May 17, 2017: IEEE Reviews in Biomedical Engineering
https://www.readbyqxmd.com/read/28534771/dynamic-graph-cuts-in-parallel
#13
Miao Yu, Shuhan Shen, Zhanyi Hu
This work aims at bridging the two important trends in efficient graph cuts in the literature, the one is to decompose a graph into several smaller subgraphs to take the advantage of parallel computation, the other is to reuse the solution of the max-flow problem on a residual graph to boost the efficiency on another similar graph. Our proposed parallel dynamic graph cuts algorithm takes the advantages of both, and is extremely efficient for certain dynamically changing MRF models in computer vision. The performance of our proposed algorithm is validated on two typical dynamic graph cuts problems: the foregroundbackground segmentation in video where similar graph cuts problems need to be solved in sequential and GrabCut where graph cuts is used iteratively...
May 16, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28534645/the-mitochondria-targeting-peptide-elamipretide-diminishes-circulating-htra2-in-st-segment-elevation-myocardial-infarction
#14
Marcus Hortmann, Samuel Robinson, Moritz Mohr, Maximillian Mauler, Daniela Stallmann, Jochen Reinöhl, Daniel Duerschmied, Karlheinz Peter, James Carr, C Michael Gibson, Christoph Bode, Ingo Ahrens
BACKGROUND: The extent of myocardial damage in patients with ST-segment elevation myocardial infarction (STEMI) depends on both the time to reperfusion as well as injury induced by ischaemia-reperfusion resulting in a cascade of cellular and humoral reactions. As a consequence of ischaemia-reperfusion in the heart, the high-temperature requirement serine peptidase 2 (HtrA2) is translocated from the mitochondria to the cytosol, whereupon it induces protease activity-dependent apoptosis mediated via caspases...
May 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28534525/covalently-linked-dengue-virus-envelope-glycoprotein-dimers-reduce-exposure-of-the-immunodominant-fusion-loop-epitope
#15
Alexander Rouvinski, Wanwisa Dejnirattisai, Pablo Guardado-Calvo, Marie-Christine Vaney, Arvind Sharma, Stéphane Duquerroy, Piyada Supasa, Wiyada Wongwiwat, Ahmed Haouz, Giovanna Barba-Spaeth, Juthathip Mongkolsapaya, Félix A Rey, Gavin R Screaton
A problem in the search for an efficient vaccine against dengue virus is the immunodominance of the fusion loop epitope (FLE), a segment of the envelope protein E that is buried at the interface of the E dimers coating mature viral particles. Anti-FLE antibodies are broadly cross-reactive but poorly neutralizing, displaying a strong infection enhancing potential. FLE exposure takes place via dynamic 'breathing' of E dimers at the virion surface. In contrast, antibodies targeting the E dimer epitope (EDE), readily exposed at the E dimer interface over the region of the conserved fusion loop, are very potent and broadly neutralizing...
May 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28534496/definitions-of-traumatic-conus-medullaris-and-cauda-equina-syndrome-a-systematic-literature-review
#16
E Brouwers, H van de Meent, A Curt, B Starremans, A Hosman, R Bartels
STUDY DESIGN: A systematic review. OBJECTIVES: Conus medullaris syndrome (CMS) and cauda equina syndrome (CES) are well-known neurological entities. It is assumed that these syndromes are different regarding neurological and functional prognosis. However, literature concerning spinal trauma is ambiguous about the exact definition of the syndromes. METHODS: A MEDLINE, EMBASE and Cochrane literature search was performed. We included original articles in which clinical descriptions of CMS and/or CES were mentioned in patients following trauma to the thoracolumbar spine...
May 23, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28534438/the-axonal-cytoskeleton-and-the-assembly-of-nodes-of-ranvier
#17
Aniket Ghosh, Diane L Sherman, Peter J Brophy
Vertebrate nervous systems rely on rapid nerve impulse transmission to support their complex functions. Fast conduction depends on ensheathment of nerve axons by myelin-forming glia and the clustering of high concentrations of voltage-gated sodium channels (Nav) in the axonal gaps between myelinated segments. These gaps are the nodes of Ranvier. Depolarization of the axonal membrane initiates the action potential responsible for impulse transmission, and the Nav help ensure that this is restricted to nodes...
May 1, 2017: Neuroscientist: a Review Journal Bringing Neurobiology, Neurology and Psychiatry
https://www.readbyqxmd.com/read/28534423/evaluating-non-technical-skills-and-mission-essential-competencies-of-pilots-in-military-aviation-environments
#18
Emmanuel Tsifetakis, Tom Kontogiannis
To develop and validate a classification of non-technical skills (NTS) in military aviation, a study was conducted, using data from real operations of F16 aircraft formations. Phase 1 developed a NTS classification based on the literature review (e.g., NOTECHS) and a workshop with pilots. The Non-TEChnical-MILitary-Skills (NOTEMILS) scheme was tested in Phase 2 in a series of Principal Component Analysis with data from After-Action-Review sessions (i.e., 900 records from a wide range of operations). The NTS were found to make a good prediction of Mission Essential Components (R square > 0,80) above the effect of experience...
May 23, 2017: Ergonomics
https://www.readbyqxmd.com/read/28534367/laparoscopic-hepatectomy-for-colorectal-liver-metastases-located-in-all-segments-of-the-liver
#19
Deqing Wu, Wulin Wu, Yong Li, Shuntian Liang, Junjiang Wang, Xueqing Yao, Zhixiang Jian
PURPOSE: Laparoscopic hepatectomy is not a well-established treatment modality for colorectal liver metastases. Moreover, most reports have been limited to tumors in the anterolateral segments (segments 2, 3, 4b, 5, and 6). We evaluated the short- and long-term outcomes after laparoscopic hepatectomy for colorectal liver metastases located in all segments, including tumors located in the posterosuperior segments (segments 1, 4a, 7, and 8). METHODS: TThis retrospective study included 102 patients who underwent laparoscopic hepatectomy for colorectal liver metastases with radical intent between January 2009 and January 2016...
March 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28534331/-application-of-bowel-plication-combined-with-early-enteral-nutrition-in-the-enhanced-recovery-after-surgery-for-neonates-with-jejunal-atresia
#20
Huan Chen, Qiming Geng, Changgui Lu, Weiwei Jiang, Jie Zhang, Xiaofeng Lyu, Wei Li, Hongxing Li, Weibing Tang
OBJECTIVE: To evaluate the efficacy of bowel plication combined with early enteral nutrition (EEN) in the enhanced recovery after surgery(ERAS) of jejunal atresia (JA) neonates. METHODS: Between January 2005 and January 2014, 58 neonates with JA underwent surgical treatment in Children's Hospital of Nanjing Medical University. Their clinical data, including operation procedures, ages, birth weight, concomitant diseases, age at surgery, hospital stay, total parenteral nutrition (TPN), postoperative intestinal function recovery (the time to the first oral feeding and the time to oral feeding volume reaching 150 ml·kg(-1)·d(-1)), complications and reoperation, were retrospectively analyzed...
May 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
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