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https://www.readbyqxmd.com/read/28337218/effect-of-transplantation-of-bone-marrow-derived-mesenchymal-stem-cells-and-platelets-rich-plasma-on-experimental-model-of-radiation-induced-oral-mucosal-injury-in-albino-rats
#1
Basma Elsaadany, Samar El Kholy, Dalia El Rouby, Laila Rashed, Tarek Shouman
Normal tissue damage following radiotherapy is still a major problem in cancer treatment. Therefore, the current work aimed at exploring the possible role of systemically injected bone marrow derived mesenchymal stem cells (BM-MSCs) and/or locally injected platelet rich plasma (PRP) in ameliorating the side effects of ionizing radiation on the rat's tongue. Twelve rats served as control group (N) and 48 rats received a single radiation dose of 13 Gy to the head and neck region; then, they were equally divided into 4 experimental groups: irradiated only (C), irradiated + MSCs (S), irradiated + (PRP) (P), and combined group (PS)...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28336419/scarf-related-injuries-at-a-major-trauma-center-in-northern-india
#2
Pritish Singh, Ashok Kumar, Vishal Shekhawat
PURPOSE: Scarf is a long loose piece of cloth worn around the neck and shoulder. Despite cultural association of this apparel, it is part of numerous injury episodes of varying enormity. Entanglement of loose scarf in spoke wheels of bike, tricycle, belt driven machines like sugarcane juice machine, thresher, grinding machines, etc is observed both in social and industrial milieu. This study aims to investigate the scarf-related injuries at a major trauma center in northern India. METHODS: From June 2013 to May 2015, a hospital-based prospective observational study was done in patients who presented to a level 1 trauma center in northern India with the mode of injury involving scarf around the neck...
March 9, 2017: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/28334406/male-and-female-cervical-spine-biomechanics-and-anatomy-implication-for-scaling-injury-criteria
#3
Narayan Yoganandan, Cameron R Bass, Liming Voo, Frank A Pintar
There is an increased need to develop female-specific injury criteria and anthropomorphic test devices (dummies) for automotive and military environments, especially as women take occupational roles traditionally reserved for men. Although some exhaustive reviews on the biomechanics and injuries of the human spine have appeared in clinical and bioengineering literatures, focus on the difference between male and female cervical spine responses and characteristics has largely been ignored. Current neck injury criteria for automotive dummies for assessing crashworthiness and occupant safety are obtained from animal and human cadaver experiments, computational modeling and human volunteer studies...
March 23, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28330802/orofacial-trauma-in-rural-india-a-clinical-study
#4
Sunita Malik, Gurdarshan Singh, Gagandeep Kaur, Sunil Yadav, Hitesh C Mittal
PURPOSE: Orofacial trauma is becoming a leading medical problem worldwide. Most of the studies pertaining to orofacial trauma have been done in urban areas but very little scientific literature is available for rural areas. METHODS: A prospective medical institute-based study of orofacial injury patients was carried out from May 2013 to April 2016 (36 Months). Data regarding incidence, age and sex distribution, causes, types and site of injury, treatment modalities and trauma associated complications were collected and analysed...
February 24, 2017: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/28328674/the-value-of-the-injury-severity-score-in-pediatric-trauma-time-for-a-new-definition-of-severe-injury
#5
Joshua B Brown, Mark L Gestring, Christine M Leeper, Jason L Sperry, Andrew B Peitzman, Timothy R Billiar, Barbara A Gaines
BACKGROUND: The Injury Severity Score (ISS) is the most commonly used injury scoring system in trauma research and benchmarking. An ISS>15 conventionally defines severe injury; however, no studies evaluate whether ISS performs similarly between adults and children. Our objective was to evaluate ISS and AIS to predict mortality and define optimal thresholds of severe injury in pediatric trauma. METHODS: Patients from the Pennsylvania trauma registry 2000-2013 were included...
March 20, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28326242/nasal-lobular-capillary-hemangioma-as-a-complication-after-an-endoscopic-transsphenoidal-gonadotrophin-producing-pituitary-adenoma-resection
#6
Dalila Forte, Amets Sagarribay Irañeta, Anabela Nabais, António Figueiredo, Manuela Mafra, Victor Gonçalves
Background Lobular capillary hemangioma is a rare benign tumor, most frequently located in the head or neck region, the nasal cavity being uncommonly affected. Its etiopathogenesis is not fully established, although traumatic and hormonal factors have been implied. Case Description A 50-year-old female patient underwent an uneventful endoscopic transsphenoidal removal of a pituitary cystic macroadenoma at our institution. Nasal packing was used in postoperative hemostasis. Histopathology was compatible with a gonadotrophin-producing adenoma...
January 2017: Journal of Neurological Surgery Reports
https://www.readbyqxmd.com/read/28323577/mitigation-of-radiation-induced-epithelial-damage-by-the-tlr5-agonist-entolimod-in-a-mouse-model-of-fractionated-head-and-neck-irradiation
#7
Ilia A Toshkov, Anatoli S Gleiberman, Vadim L Mett, Alan D Hutson, Anurag K Singh, Andrei V Gudkov, Lyudmila G Burdelya
Radiation treatment of head and neck cancer frequently causes severe collateral damage to normal tissues including mouth mucosa, salivary glands and skin. This toxicity limits the radiation dose that can be delivered and affects the patient's quality of life. Previous studies in mice and nonhuman primates showed that entolimod, a toll-like receptor 5 (TLR5) agonist derived from bacterial flagellin, effectively reduced radiation damage to hematopoietic and gastrointestinal tissues in both total-body and local irradiation scenarios, with no protection of tumors...
March 21, 2017: Radiation Research
https://www.readbyqxmd.com/read/28319792/safety-regulation-in-professional-football-empirical-evidence-of-intended-and-unintended-consequences
#8
Andrew Hanson, Nicholas A Jolly, Jeremy Peterson
In response to increasing public awareness and negative long-term health effects of concussions, the National Football League implemented the "Crown-of-the-Helmet Rule" (CHR). The CHR imposes penalties on players who initiate contact using the top of the helmet. This paper examines the intended effect of this policy and its potential for unintended consequences. We find evidence supporting the intended effect of the policy- a reduction in weekly concussion reports among defensive players by as much as 32% (34% for all head and neck injuries), but also evidence of an increase in weekly lower extremity injury reports for offensive players by as much as 34%...
January 29, 2017: Journal of Health Economics
https://www.readbyqxmd.com/read/28318626/the-leukotriene-b4-leukotriene-b4-receptor-axis-promotes-cisplatin-induced-acute-kidney-injury-by%C3%A2-modulating-neutrophil-recruitment
#9
Bo Deng, Yuli Lin, Shuai Ma, Yin Zheng, Xuguang Yang, Bingji Li, Wenyan Yu, Qingqing Xu, Tingyan Liu, Chuanming Hao, Rui He, Feng Ding
Cisplatin is an effective chemotherapeutic agent and widely used in treatment of various solid organ malignancies, including head and neck, ovarian, and testicular cancers. However, the induction of acute kidney injury (AKI) is one of its main side effects. Leukotriene B4 receptor 1 (BLT1) mediates the majority of physiological effects of leukotriene B4 (LTB4), a potent lipid chemoattractant generated at inflammation sites, but the role of the LTB4-BLT1 axis in cisplatin-induced AKI remains unknown. Here we found upregulated LTB4 synthesis and BLT1 expression in the kidney after cisplatin administration...
March 15, 2017: Kidney International
https://www.readbyqxmd.com/read/28315184/epiphyseal-arterial-network-and-inferior-retinacular-artery-seem-critical-to-femoral-head-perfusion-in-adults-with-femoral-neck-fractures
#10
Dewei Zhao, Xing Qiu, Benjie Wang, Zihua Wang, Wei Wang, Jun Ouyang, Rona M Silva, Xiaotian Shi, Kai Kang, Dachuan Xu, Chuang Li, Shizhen Zhong, Yu Zhang, Kent E Pinkerton
BACKGROUND: A better understanding of the blood supply of the femoral head is essential to guide therapeutic strategies for patients with femoral neck fractures. However, because of the limitations of conventional techniques, the precise distribution and characteristics of intraosseous arteries of the femoral head are not well displayed. QUESTIONS/PURPOSES: To explore the characteristics and interconnections of the intraosseous vessel system between different areas of the femoral head and the possible blood supply compensatory mechanism after femoral neck fracture...
March 17, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28302280/blunt-cerebrovascular-injury-in-children
#11
Stephen J Fenton, Robert J Bollo
Blunt cerebrovascular injury in children is an uncommon occurrence that if missed and left untreated can result in devastating long-term neurologic consequences. Diagnosis can be readily obtained by a computed tomographic angiogram of the head and neck. If confirmed, treatment with antithrombotic therapy dramatically reduces the risk of a cerebrovascular accident. The difficulty lies in determining which child should be screened for such an injury. Several institutions have come up with criteria for screening...
February 2017: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/28301443/can-neck-strength-be-measured-using-a-single-maximal-contraction-in-a-simulated-contact-position
#12
Danielle M Salmon, Phil Handcock, S John Sullivan, Nancy J Rehrer, Brian Niven
Neck strengthening has been postulated to potentially reduce the incidence/severity of concussions and neck injuries in collision based sports. A quick and reliable method to assess neck strength would permit identification of those at risk and tracking of progress following injury. The purpose of this study was to determine if neck strength could be reliably assessed in a simulated contact posture using a single maximal contraction. During a single session 30 healthy male university students performed 3 maximal voluntary contractions of the neck musculature in each of the following directions: extension (Ext), flexion (Flx), left (LtFlx), and right lateral flexion (RtFlx)...
March 13, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28300741/unusual-route-of-a-bullet-from-scapula-to-eye
#13
Elif Demirkilinc Biler, Melis Palamar Onay, Naim Ceylan, Bilge Yildirim Ceper
Herein, an awkward case of globe perforation with a bullet-entering from the right posterior scapular region and leaving the body from the right orbit through the eye - is reported. Route of the bullet could be devastating - as it passed through the neck and the maxillofacial region-however by chance no vital damage occurred. Its path was assessed by plain radiography and computed tomography scans. Sometimes prediction of the trajectory is very difficult without additional radiological investigations. Especially, in the case of any high velocity projectile wounding, physician must be aware of the fact that the bullet's course will not be a linear but most probably a complicated one...
January 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28298051/a-systematic-review-and-appraisal-of-clinical-practice-guidelines-for-musculoskeletal-soft-tissue-injuries-and-conditions
#14
Daniel Pincus, John E Kuhn, Ujash Sheth, Katie Rizzone, Kristi Colbenson, Tim Dwyer, Ashley Karpinos, Paul H Marks, David Wasserstein
BACKGROUND: Clinical practice guidelines (CPGs) are published by several sports medicine institutions. A systematic evaluation can help identify the highest quality CPGs for clinical use and identify any deficiencies that remain. PURPOSE: To identify and appraise CPGs relevant to clinical sports medicine professionals. STUDY DESIGN: Systematic review. METHODS: Predetermined selection criteria were utilized by 2 reviewers who independently identified published CPGs before January 1, 2014...
October 1, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28296813/comparison-of-outcomes-between-c1-c2-screw-hook-fixation-and-c1-c2-screw-rod-fixation-for-treating-reducible-atlantoaxial-dislocation
#15
Bin Ni, Wenlong Zhao, Qunfeng Guo, Mei Zhang, Jinshui Chen, Xiang Guo, Xuhua Lu, Ning Xie
STUDY DESIGN: Retrospective comparative study OBJECTIVE.: To compare the outcomes of C1-C2 transarticular screw with C1 laminar hook (TAS+ C1H) fixation and C1 trans-arch lateral mass screw with C2 pedicle screw (C1TLMS+ C2PS) fixation in the treatment of reducible atlantoaxial dislocation(AAD). SUMMARY OF BACKGROUND DATA: TAS+ C1H is comparable to TAS with posterior wiring techniques and superior to C1 lateral mass screw combined with C2 pedicle screw (C1LMS+ C2PS) in biomechanics...
March 14, 2017: Spine
https://www.readbyqxmd.com/read/28291488/patient-litter-system-response-in-a-full-scale-ch-46-crash-test
#16
Charles A Weisenbach, Tyler Rooks, Troy Bowman, Vince Fralish, B Joseph McEntire
U.S. Military aeromedical patient litter systems are currently required to meet minimal static strength performance requirements at the component level. Operationally, these components must function as a system and are subjected to the dynamics of turbulent flight and potentially crash events. The first of two full-scale CH-46 crash tests was conducted at NASA's Langley Research Center and included an experiment to assess patient and litter system response during a severe but survivable crash event. A three-tiered strap and pole litter system was mounted into the airframe and occupied by three anthropomorphic test devices (ATDs)...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28291460/validation-of-laboratory-animal-and-surrogate-human-models-in-primary-blast-injury-studies
#17
Namas Chandra, Aravind Sundaramurthy, Raj K Gupta
Blast-induced neurotrauma has affected more than 300,000 service members. It is important to understand the effect of single and repeated shock-blast wave exposures on the neuropsychological behavior of soldiers, to offer them better protection, diagnostics, and treatment. Preclinical animal models and helmet design studies on human surrogate models have relied on the use of compression gas-driven shock tubes. Traditional shock tubes are so simple that if not carefully designed and operated, the test results can easily introduce detrimental artifacts clouding the conclusions...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28289904/shoulder-arthroscopy-combined-to-hardware-removal-in-proximal-humeral-fractures-a-series-of-58-cases-with-a-mean-follow-up-of-2%C3%A2-years
#18
Ch Maroun, D Aliani, A Hass, J D Werthel, Anne Vidil, Ph Valenti
BACKGROUND: Proximal humerus fractures are common injuries. Locking plates and anterograde medullary nails are the two most common fixation devices used when open reduction and internal fixation (ORIF) is indicated. Complications related to fracture and to hardware are numerous, especially shoulder stiffness. The goal of this study is to report the clinical outcomes of gleno-humeral arthroscopic arthrolysis combined with hardware removal. METHODS: A total of 58 patients (25 men, 33 women) with a mean age of 58 years (24-79) were reviewed retrospectively...
March 13, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28289137/nursery-product-related-injuries-treated-in-united-states-emergency-departments
#19
Christopher E Gaw, Thiphalak Chounthirath, Gary A Smith
OBJECTIVE: The goal of this study was to determine the epidemiology of injuries associated with nursery products among young children treated in US emergency departments. METHODS: Data from the National Electronic Injury Surveillance System were retrospectively analyzed for patients aged <3 years who sustained an injury associated with a nursery product from 1991 through 2011. RESULTS: An estimated 1 391 844 (95% confidence interval, 1 169 489-1 614 199) nursery product-related injuries among children aged <3 years were treated in US emergency departments during the 21-year study period, averaging 56...
March 13, 2017: Pediatrics
https://www.readbyqxmd.com/read/28286845/pan-vs-selective-computed-tomography-scans-in-management-of-multiple-trauma-patients-a-brief-report
#20
Anita Sabzghabaei, Majid Shojaee, Hamid Kariman, Mohammad Manouchehrifar, Kamran Heydari, Sirus Sohrabi
INTRODUCTION: Using pan or selective computed tomography (CT) scan in management of multiple trauma patient is a matter of debate. Therefore, the present study was designed aiming to compare the findings of pan and selective CT scans in management of multiple trauma patients. METHOD: This is a prospective cross-sectional study, on patients presented to the emergency department (ED) of Shohadaye Haftome Tir Hospital, Tehran, Iran, following blunt multiple trauma over a 1-year period, from March 2014 to March 2015...
2017: Emergency (Tehran, Iran)
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