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https://www.readbyqxmd.com/read/28636769/is-cannabis-treatment-for-anxiety-mood-and-related-disorders-ready-for-prime-time
#1
REVIEW
Jasmine Turna, Beth Patterson, Michael Van Ameringen
Anxiety and related disorders are the most common mental conditions affecting the North American population. Despite their established efficacy, first-line antidepressant treatments are associated with significant side effects, leading many afflicted individuals to seek alternative treatments. Cannabis is commonly viewed as a natural alternative for a variety of medical and mental health conditions. Currently, anxiety ranks among the top five medical symptoms for which North Americans report using medical marijuana...
June 21, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28636768/driving-aggression-and-anxiety-intersections-assessment-and-interventions
#2
Heidi M Zinzow, Stephanie M Jeffirs
OBJECTIVE: Driving aggression and anxiety are significant contributors to risky driving and motor vehicle crashes (MVCs), which are leading causes of U.S. morbidity and mortality. Even though aggression and anxiety can be conceptualized as related features of the fight-or-flight response, literature on these topics has not been integrated. Driving aggression and anxiety are also transdiagnostic constructs that span multiple psychiatric disorders. Assessment and treatment of these complex problems must be understood to reduce the public health burden of MVCs...
June 21, 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28636645/genetic-susceptibility-in-juvenile-myoclonic-epilepsy-systematic-review-of-genetic-association-studies
#3
Bruna Priscila Dos Santos, Chiara Rachel Maciel Marinho, Thalita Ewellyn Batista Sales Marques, Layanne Kelly Gomes Angelo, Maísa Vieira da Silva Malta, Marcelo Duzzioni, Olagide Wagner de Castro, João Pereira Leite, Fabiano Timbó Barbosa, Daniel Leite Góes Gitaí
BACKGROUND: Several genetic association investigations have been performed over the last three decades to identify variants underlying Juvenile Myoclonic Epilepsy (JME). Here, we evaluate the accumulating findings and provide an updated perspective of these studies. METHODOLOGY: A systematic literature search was conducted using the PubMed, Embase, Scopus, Lilacs, epiGAD, Google Scholar and Sigle up to February 12, 2016. The quality of the included studies was assessed by a score and classified as low and high quality...
2017: PloS One
https://www.readbyqxmd.com/read/28635987/integrative-review-of-facility-interventions-to-manage-compassion-fatigue-in-oncology-nurses
#4
Dorien Wentzel, Petra Brysiewicz
PROBLEM IDENTIFICATION: Oncology nurses are regularly exposed to high-stress situations that may lead to compassion fatigue, and many institutions have implemented interventions to reduce burnout in nurses, but knowledge on the feasiblity, effectiveness, and nurses' experience of interventions is lacking.
. LITERATURE SEARCH: Electronic search of literature published from 1992-2015 was performed to evaluate in-facility interventions to manage compassion fatigue in oncology nurses...
May 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28635978/vaginal-testosterone-for-management-of-aromatase-inhibitor-related-sexual-dysfunction-an-integrative-review
#5
Emily A Lemke, Lydia T Madsen, Joyce E Dains
PROBLEM IDENTIFICATION: Women taking aromatase inhibitors (AIs) as part of the management of hormone receptor-positive breast cancer experience more symptoms of sexual dysfunction, including vaginal atrophy, as opposed to postmenopausal women and women treated with tamoxifen (Nolvadex®). Vaginal testosterone could be an alternative to estrogen, which is contraindicated in this population.
. LITERATURE SEARCH: A systematic review was completed by searching PubMed and Scopus databases...
May 1, 2017: Oncology Nursing Forum
https://www.readbyqxmd.com/read/28635682/relationship-between-human-mutl-homolog-1-hmlh1-hypermethylation-and-colorectal-cancer-a-meta-analysis
#6
Hui-Feng Zhang, You-Wang Lu, Zhen-Rong Xie, Kun-Hua Wang
BACKGROUND Hypermethylation of CpG islands in gene promoter regions is an important mechanism of gene inactivation in cancers. Promoter hypermethylation of human mutL homolog 1 (hMLH1) has been implicated in a subset of colorectal cancers that show microsatellite instability (MSI), while the connection of the epigenetic inactivation of hMLH1 in colorectal cancers remains unknown. The aim of this study was to evaluate the relationship between the promoter hypermethylation of hMLH1 and colorectal cancers by performing a meta-analysis...
June 21, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28635320/book-review-a-concise-introduction-to-mental-health-in-canada-a-concise-introduction-to-mental-health-in-canada-second-edition-goldner-elliott-m-jenkins-emily-bilsker-dan-toronto-ontario-canadian-scholars-press-2016-371-pages-book-3731-cdn-79-95-reviewer-rating
#7
https://www.readbyqxmd.com/read/28635182/the-effect-of-flaxseed-supplementation-on-body-weight-and-body-composition-a-systematic-review-and-meta-analysis-of-45-randomized-placebo-controlled-trials
#8
REVIEW
M Mohammadi-Sartang, Z Mazloom, H Raeisi-Dehkordi, R Barati-Boldaji, N Bellissimo, J O Totosy de Zepetnek
Flaxseed consumption may be inversely associated with obesity; however, findings of available randomized controlled trials (RCTs) are conflicting. The present study aimed to systematically review and analyse RCTs assessing the effects of flaxseed consumption on body weight and body composition. PubMed, Medline via Ovid, SCOPUS, EMBASE and ISI Web of Sciences databases were searched up to November 2016. Mean changes in body composition indices including body weight, body mass index (BMI) and waist circumference were extracted...
June 21, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28635097/new-ideas-for-old-concerns-d-prinsley-australian-scholarly-publishing-melbourne-2013-isbn-9781925003451-paperback-a-34-95
#9
Michael Bauer, Yvonne Wells
No abstract text is available yet for this article.
June 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28634764/are-wrongful-life-actions-threatening-the-value-of-human-life
#10
Vera Lúcia Raposo
Most courts around the world have been refusing wrongful life actions. The main argument invoked is that the supposed compensable injury cannot be classified as such, since life is always a blessing no matter how hard and painful it is.In opposition to mainstream scholars and the dominant case law, this article sustains that life must be distinguished from living conditions, the former being the real injury at stake, since some living conditions are so intolerable that in themselves they justify a compensation within wrongful life actions...
June 20, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28634455/fertilizing-a-patient-engagement-ecosystem-to-innovate-healthcare-toward-the-first-italian-consensus-conference-on-patient-engagement
#11
Guendalina Graffigna, Serena Barello, Giuseppe Riva, Mariarosaria Savarese, Julia Menichetti, Gianluca Castelnuovo, Massimo Corbo, Alessandra Tzannis, Antonio Aglione, Donato Bettega, Anna Bertoni, Sarah Bigi, Daniela Bruttomesso, Claudia Carzaniga, Laura Del Campo, Silvia Donato, Silvia Gilardi, Chiara Guglielmetti, Michele Gulizia, Mara Lastretti, Valeria Mastrilli, Antonino Mazzone, Giovanni Muttillo, Silvia Ostuzzi, Gianluca Perseghin, Natalia Piana, Giuliana Pitacco, Gianluca Polvani, Massimo Pozzi, Livio Provenzi, Giulia Quaglini, Mariagrazia Rossi, Paola Varese, Natalia Visalli, Elena Vegni, Walter Ricciardi, A Claudio Bosio
Currently we observe a gap between theory and practices of patient engagement. If both scholars and health practitioners do agree on the urgency to realize patient engagement, no shared guidelines exist so far to orient clinical practice. Despite a supportive policy context, progress to achieve greater patient engagement is patchy and slow and often concentrated at the level of policy regulation without dialoguing with practitioners from the clinical field as well as patients and families. Though individual clinicians, care teams and health organizations may be interested and deeply committed to engage patients and family members in the medical course, they may lack clarity about how to achieve this goal...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28633660/a-re-assessment-of-the-safety-of-silver-in-household-water-treatment-rapid-systematic-review-of-mammalian-in-vivo-genotoxicity-studies
#12
REVIEW
Lorna Fewtrell, Batsirai Majuru, Paul R Hunter
BACKGROUND: Despite poor evidence of their effectiveness, colloidal silver and silver nanoparticles are increasingly being promoted for treating potentially contaminated drinking water in low income countries. Recently, however, concerns have been raised about the possible genotoxicity of particulate silver. OBJECTIVES: The goal of this paper was to review the published mammalian in vivo genotoxicity studies using silver micro and nanoparticles. METHODS: SCOPUS and Medline were searched using the following search string: ("DNA damage" OR genotox* OR Cytotox* OR Embryotox*) AND (silver OR AgNP)...
June 20, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28633395/is-sarcopenia-associated-with-depression-a-systematic-review-and-meta-analysis-of-observational-studies
#13
Ke-Vin Chang, Tsai-Hsuan Hsu, Wei-Ting Wu, Kuo-Chin Huang, Der-Sheng Han
Objectives: to explore whether sarcopenia is associated with depression. Design: electronic literature databases from PubMed, Scopus, Embase and Google Scholar were searched. A systematic review and meta-analysis of observational studies was conducted. Setting: community and outpatient clinic. Participants: people with and without diagnoses of sarcopenia. Measurements: outcome measures of depression...
June 14, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28633168/integration-of-clinical-pharmacists-in-family-medicine-residency-programs
#14
Jody L Lounsbery, Jennie B Jarrett, Lori M Dickerson, Stephen A Wilson
BACKGROUND AND OBJECTIVES: Clinical pharmacists are valued educators and practitioners within family medicine residency programs (FMRPs). Since the last survey of clinical pharmacists within FMRPs, there have been significant advancements to pharmacy education and training as well as growth of interprofessional education and collaborative practice within family medicine. The objective of this study is to describe the integration of clinical pharmacists within FMRPs. METHODS: All 480 Accreditation Council for Graduate Medical Education (ACGME)-approved FMRPs were contacted to identify clinical pharmacists involved with their programs...
June 2017: Family Medicine
https://www.readbyqxmd.com/read/28633088/second-line-with-oxaliplatin-or-irinotecan-based-chemotherapy-for-gemcitabine-pretreated-pancreatic-cancer-a-systematic-review
#15
REVIEW
Fausto Petrelli, Alessandro Inno, Antonio Ghidini, Lorenza Rimassa, Gianluca Tomasello, Roberto Labianca, Sandro Barni
BACKGROUND: oxaliplatin (OXA)- and irinotecan (IRI)-based chemotherapies are the most frequently used salvage regimens in patients with metastatic pancreatic cancer (PC) after first-line gemcitabine-based therapy. There are no prospective comparisons of these regimens in this setting. We conducted a systematic review of published trials to compare the efficacy of these treatments. METHODS: studies that enrolled patients with stage IV disease receiving chemotherapy with OXA or IRI plus fluoropyrimidines were identified using electronic databases (Pubmed, Embase, SCOPUS, CINAHL, Web of Science and Cochrane Library)...
June 17, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28632926/meta-analysis-of-health-related-quality-of-life-after-minimally-invasive-versus-open-oesophagectomy-for-oesophageal-cancer
#16
REVIEW
J H Kauppila, S Xie, A Johar, S R Markar, P Lagergren
BACKGROUND: The aim of this systematic review and meta-analysis was to compare health-related quality of life (HRQoL) outcomes between minimally invasive and open oesophagectomy for cancer at different postoperative time points. METHODS: A search of PubMed (MEDLINE), Web of Science, Embase, Scopus, CINAHL and the Cochrane Library was performed for studies that compared open with minimally invasive oesophagectomy. A random-effects meta-analysis was conducted for studies that measured HRQoL scores using the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 and QLQ-OES18 questionnaires...
June 20, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28632733/ponseti-method-in-the-management-of-clubfoot-under-2-years-of-age-a-systematic-review
#17
Balasankar Ganesan, Ameersing Luximon, Adel Al-Jumaily, Suchita Kothe Balasankar, Ganesh R Naik
BACKGROUND: Congenital talipes equinovarus (CTEV), also known as clubfoot, is common congenital orthopedic foot deformity in children characterized by four components of foot deformities: hindfoot equinus, hindfoot varus, midfoot cavus, and forefoot adduction. Although a number of conservative and surgical methods have been proposed to correct the clubfoot deformity, the relapses of the clubfoot are not uncommon. Several previous literatures discussed about the technical details of Ponseti method, adherence of Ponseti protocol among walking age or older children...
2017: PloS One
https://www.readbyqxmd.com/read/28632599/publication-productivity-of-orthopaedic-surgery-chairs
#18
Boris A Zelle, Michael A Weathers, Roberto J Fajardo, Varan Haghshenas, Mohit Bhandari
BACKGROUND: As academic leaders, orthopaedic chairs represent role models for scholarly activities. Despite the importance of journal publications as a measure of scholarly activity, data on the publication productivity of orthopaedic chairs remain limited. The goals of this study were to record the publication productivity of orthopaedic chairs and evaluate the extent to which they maintained their scholarly activity while serving as chairs. METHODS: The chairs of all orthopaedic residency programs in the United States were identified through the Accreditation Council for Graduate Medical Education (ACGME) web site, and were confirmed by information found on the web site of each orthopaedic program that was included in the study...
June 21, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28632445/critique-and-contribute-a-practice-based-framework-for-improving-critical-data-studies-and-data-science
#19
Gina Neff, Anissa Tanweer, Brittany Fiore-Gartland, Laura Osburn
What would data science look like if its key critics were engaged to help improve it, and how might critiques of data science improve with an approach that considers the day-to-day practices of data science? This article argues for scholars to bridge the conversations that seek to critique data science and those that seek to advance data science practice to identify and create the social and organizational arrangements necessary for a more ethical data science. We summarize four critiques that are commonly made in critical data studies: data are inherently interpretive, data are inextricable from context, data are mediated through the sociomaterial arrangements that produce them, and data serve as a medium for the negotiation and communication of values...
June 2017: Big Data
https://www.readbyqxmd.com/read/28632280/implantable-cardioverter-defibrillators-for-primary-prevention-in-patients-with-ischemic-or-nonischemic-cardiomyopathy-a-systematic-review-and-meta-analysis
#20
Michalina Kolodziejczak, Felicita Andreotti, Mariusz Kowalewski, Antonino Buffon, Marco Matteo Ciccone, Gianfranco Parati, Pietro Scicchitano, Julia M Uminska, Stefano De Servi, Kevin P Bliden, Jacek Kubica, Alessandro Bortone, Filippo Crea, Paul Gurbel, Eliano P Navarese
Background: Implantable cardioverter-defibrillators (ICDs) have a role in preventing cardiac arrest in patients at risk for life-threatening ventricular arrhythmias. Purpose: To compare ICD therapy with conventional care for the primary prevention of death of various causes in adults with ischemic or nonischemic cardiomyopathy. Data Sources: MEDLINE, Cochrane Central Register of Controlled Trials, Google Scholar, and EMBASE databases, as well as several Web sites, from 1 April 1976 through 31 March 2017...
June 27, 2017: Annals of Internal Medicine
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