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Waleed M Sweileh, Naser Y Shraim, Samah W Al-Jabi, Ansam F Sawalha, Belal Rahhal, Rasha A Khayyat, Sa'ed H Zyoud
BACKGROUND: A wide variety of probiotic products has been introduced into the market in the past decade. Research trends and activity on probiotics help understand how these products were evolved and their potential future role in medicine. The objective of this study was to assess the research activity on probiotics in pediatrics using bibliometric indicators and network visualization. METHODS: Original and review articles on probiotics in pediatrics published worldwide were retrieved from SciVerse, Scopus (1994-2014) and analyzed...
2016: World Allergy Organization Journal
Ashley A Stratton-Powell, Kinga M Pasko, Claire L Brockett, Joanne L Tipper
BACKGROUND: Polyetheretherketone (PEEK) and its composites are polymers resistant to fatigue strain, radiologically transparent, and have mechanical properties suitable for a range of orthopaedic applications. In bulk form, PEEK composites are generally accepted as biocompatible. In particulate form, however, the biologic response relevant to joint replacement devices remains unclear. The biologic response to wear particles affects the longevity of total joint arthroplasties. Particles in the phagocytozable size range of 0...
November 2016: Clinical Orthopaedics and related Research
Caitlin Dunne, Carole Lawrence, Arianne Albert, Jon C Havelock
BACKGROUND: To study whether the length of controlled ovarian stimulation affects in vitro fertilization (IVF) cycle outcomes. METHODS: This retrospective cohort study was performed at a private, university-affiliated fertility centre. We reviewed1522 IVF cycles, comprising 979 long gonadotropin-releasing hormone (GnRH) agonist and 543 GnRH antagonist protocols. All subjects underwent controlled ovarian stimulation followed by fresh embryo transfer. Logistic regression analysis was used to examine the relationship between trigger day and the following cycle outcomes: normal fertilization rate (FR), proportion of mature oocytes, proportion of cycles with embryos for cryopreservation, and clinical pregnancy rate (CPR)...
June 8, 2016: Minerva Ginecologica
Ryan Siskey, Jonathan Peck, Hitesh Mehta, Allison Kosydar, Steven Kurtz, Genevieve Hill
BACKGROUND CONTEXT: Total disc arthroplasty is an alternative therapy to spinal fusion for the treatment of neck or low back pain and is hypothesized to reduce the risk of disease progression to the adjacent spinal levels. Radiographic and retrieval analyses of various total disc replacements (TDRs) have shown evidence of impingement damage. Impingement of TDRs can occur when the device reaches the limits of its functional range of motion, causing contact between peripheral regions of the device...
September 2016: Spine Journal: Official Journal of the North American Spine Society
Kavitha Chikkanayakanahalli Venugopal, Suresh Ramappa Melsakkare, Sahana R Manipur, Pavana Acharya, Lakshmi Bomalapura Ramamurthy
CONTEXT: In developing countries, corneal diseases are the second leading cause of blindness. This corneal blindness can be treated through corneal transplantation. Though the present infrastructure is strong enough to increase keratoplasty numbers at a required rate, India has largest corneal blind population in the world. So a constant supply of high quality donor corneal tissue is the key factor for reduction of prevalence of corneal blindness. Considering the magnitude of corneal blindness and shortage of donor cornea, there is a huge gap in the demand and supply...
August 2015: Journal of Clinical and Diagnostic Research: JCDR
M Guren Dolu, A Canbolat Ayhan, M Erguven, C Timur, A Yoruk, S Ozdemir
AIM: Aim of the study was to assess bone metabolism disturbances in children with acute lymphoblastic leukemia following cessation of chemotherapy. For this purpose we measured bone mineral density (BMD) and evaluated bone metabolism markers. METHODS: Seventy-five patients (37 female, 38 males, mean age 10.77±3.80 years) were included. Lumbar spine BMD was measured by dual energy X-ray absorptiometry and serum calcium, phosphorus, magnesium, alkaline phosphatase, parathyroid hormone and 25OH vitamin D levels were analyzed...
October 2015: Minerva Pediatrica
Jia-Qi Yuan, Shou-Man Wang, Li-Li Tang, Jie Mao, Yu-Hui Wu, Jian Hai, Sha-Yang Luo, Hui-Ying Ou, Lei Guo, Li-Qiu Liao, Jun Huang, Yan Li, Zhi Xiao, Ke-Jing Zhang, Na Luo, Fei-Yu Chen
To investigate the relationship between chemotherapy dose intensity and therapy efficacy of different molecular subtypes. Clinical and pathological features of the patients with breast cancer were retreived from the hospital records. 315 patients were analyzed (251 showed clinical response, 38 acquired pCR). Patients with positive ER status, negative PR status, higher Ki67 level and higher RTDI had better therapy response. 13.5 and 84.5 % were identified the benchmark of Ki67 and RTDI, respectively. As the result of interior-subgroup comparison, luminal subgroups acquired better response rate when RTDI ≥ 84...
June 2015: Breast Cancer Research and Treatment
Ramón Candia-Luján, José Antonio De Paz Fernández, Osvaldo Costa Moreira
INTRODUCTION: In recent years, antioxidant supplements have become popular to counter the effects of free radicals and muscle damage symptoms, including delayed onset muscle soreness (DOMS). AIM: To conduct a systematic review in different databases to determine the effects of antioxidant supplements on DOMS. METHODS: We conducted a search in databases; Cochrane, Pubmed, Scopus and SportDiscus and Web of Science (WOS). The words and acronyms used were; Delayed onset muscle soreness, exercise induced muscle damage, DOMS, EIMD, antioxidant and oxidative stress...
October 5, 2014: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Paolo Chiari, Cristiana Forni, Daniela Mosci, Renate Warasin
Indications on how to retrieve clinical practice guidelines are offered, presenting the main agencies that produce guidelines and the trip database. A google search with the key word nursing guidelines, after a selection of agencies with multiprofessional groups, with an explicit process of bibliographic search and a grading of recommendations produced the selection of 4 agencies.
October 2014: Assistenza Infermieristica e Ricerca: AIR
Shalini Singh, Shyamali Sarma, Shashank P Katiyar, Mousumi Das, Ruchika Bhardwaj, Durai Sundar, Vikash Kumar Dubey
Hypericin, a natural compound from Hypericum perforatum (St. John's wort), has been identified as a specific inhibitor of Leishmania donovani spermidine synthase (LdSS) using integrated computational and biochemical approaches. Hypericin showed in vitro inhibition of recombinant LdSS enzyme activity. The in vivo estimation of spermidine levels in Leishmania promastigotes after hypericin treatment showed significant decreases in the spermidine pools of the parasites, indicating target specificity of the inhibitor molecule...
January 2015: Antimicrobial Agents and Chemotherapy
Saadettin Kilickap, Yalcin Kaya, Birsen Yucel, Ersin Tuncer, Nalan Akgul Babacan, Sahande Elagoz
BACKGROUND: The prognostic value of the Ki67 expression level is yet unclear in breast cancer. The aim of this study was to investigate the association between Ki67 expression levels and prognostic factors such as grade, Her2 and hormone receptor expression status in breast cancers. MATERIALS AND METHODS: Clinical and pathological features of the patients with breast cancer were retreived from the hospital records. RESULTS: In this study, 163 patients with breast cancer were analyzed, with a mean age of 53...
2014: Asian Pacific Journal of Cancer Prevention: APJCP
Daniel C Pimentel, Omar El Abd, Ramsin M Benyamin, Anna M Buehler, Victor F Leite, Danesh Mazloomdoost, Janini Chen, Wu Tu Hsing, Joao E D Amadera
BACKGROUND: Low back pain, with or without radiculopathy, is an important cause of disability and economic expenditure. However, many patients are not achieving optimal pain control with existing medications. Tumor necrosis factor antagonists (anti-TNFα) could be an alternative drug treatment. OBJECTIVES: Systematic review the efficacy and safety of anti-TNFα in the treatment of low back pain with or without radiculopathy. STUDY DESIGN: Inclusion criteria were observational studies with safety as an outcome, and randomized or nonrandomized controlled trial (RCT) studies on efficacy and/or safety of anti-TNFα drugs on low back pain...
January 2014: Pain Physician
Atul K Khandelwal, Santosh K Singh, Devendra Pawar, Shivani Khandelwal, Sachit Sharma
Foreign bodies in bladder being unusual in the clinical setting present as a diagnostic dilemma with the history being vague as highlighted by the present case of a 15 years old boy who was found to have long electrical wire coiled together in the bladder extending into whole urethra. Cystoscopic retreival was not possible as the wire had formed a huge coiled mass with knotting. The wire was removed by a suprapubic cystostomy. Postoperative period was uneventful.
June 2013: Indian Journal of Surgery
Neeraj Kumar Goyal, Apul Goel, Satyanarayan Sankhwar
Symptomatic prostatic calculi are a rare clinical entity with wide range of management options, however, there is no agreement about the preferred method for treating these symptomatic calculi. In this study we describe our experience of transurethral management of symptomatic prostatic calculi using holmium-YAG laser lithotripsy. Patients with large, symptomatic prostatic stones managed by transurethral lithotripsy using holmium-YAG laser over 3-year duration were included in this retrospective study. Patients were evaluated for any underlying pathological condition and calculus load was determined by preoperative X-ray KUB film/CT scan...
August 2013: Urolithiasis
Izet Masic
This article describes the methodology of preparation, writing and publishing scientific papers in biomedical journals. given is a concise overview of the concept and structure of the System of biomedical scientific and technical information and the way of biomedical literature retreival from worldwide biomedical databases. Described are the scientific and professional medical journals that are currently published in Bosnia and Herzegovina. Also, given is the comparative review on the number and structure of papers published in indexed journals in Bosnia and Herzegovina, which are listed in the Medline database...
June 2011: Acta Informatica Medica: AIM
Vincent L Biron, Adil Mohamed, Michael J Hendzel, D Alan Underhill, Hadi Seikaly
BACKGROUND: Epigenetic modifications are defined as heritable changes in gene expression that are not encoded in deoxyribonucleic acid (DNA). Despite the importance of epigenetics in tumorigenesis, there is a paucity of information regarding the epigenetic profiles of oropharyngeal squamous cell carcinoma (OPSCC). OBJECTIVE: The objective of this study was to identify epigenetic signatures associated with human papillomavirus (HPV)-positive and -negative OPSCC. METHODS: We collected demographic, pathologic, and survival data from 44 patients with advanced-stage OPSCC treated with surgery and chemoradiation at the University of Alberta between January 2006 and December 2008...
April 2012: Journal of Otolaryngology—Head & Neck Surgery
Lionel Landré, Christophe Destrieux, Frédéric Andersson, Laurent Barantin, Yann Quidé, Géraldine Tapia, Nematollah Jaafari, David Clarys, Philippe Gaillard, Michel Isingrini, Wissam El-Hage
BACKGROUND: Posttraumatic stress disorder (PTSD) is associated with medial frontal and amygdala functional alterations during the processing of traumatic material and frontoparietal dysfunctions during working memory tasks. This functional magnetic resonance imaging (fMRI) study investigated the effects of trauma-related words processing on working memory in patients with PTSD. METHODS: We obtained fMRI scans during a 3-back task and an identity task on both neutral and trauma-related words in women with PTSD who had been sexually abused and in healthy, nonexposed pair-matched controls...
February 2012: Journal of Psychiatry & Neuroscience: JPN
Tahir Karadeniz, Caner Baran, Medih Topsakal, Ender Kavukcu
PURPOSE: To evaluate the effect of the number of dissected lymph nodes (LNs) during radical cystectomy on survival outcomes. MATERIALS AND METHODS: Medical files of 211 patients who underwent cystectomy between 1996 and 2009 were retrospectively evaluated. Seventy-four patients were included in the study and divided into two groups regarding the median number of retrieved LNs (median number = 13); 36 patients in the 1st and 38 in the 2nd group. Radical cystectomy, urinary diversion, and pelvic LN dissection were done in all the patients...
2011: Urology Journal
Marko Kolsek
The author describes problems related to the implementation of electronic medical record in family medicine in Slovenia since 1992 when first personal computers have been delivered to family physicians' practices. The situation of health care informatization and implementation of electronic medical record in primary health care in new countries, other former Yugoslav republics, is described. There are rather big differences among countries and even among some regions of one country, but in the last year the situation improved, especially in Montenegro, Serbia and Slovenia...
November 2009: Srpski Arhiv za Celokupno Lekarstvo
Cem Akarsu, Gamze Cağlar, Kubilay Vicdan, Eran Sözen, Kutay Biberoğlu
OBJECTIVE: To document the relationship between smooth endoplasmic reticulum (SER) aggregations and recurrent fetal anomalies. DESIGN: Case report. SETTING: Private IVF center. PATIENT(S): A 28-year-old woman with an 11-year history of primary infertility. INTERVENTION(S): Three consecutive cycles of intracytoplasmic sperm injection (ICSI) in the same patient. MAIN OUTCOME MEASURE(S): Clinical pregnancy, live birth, fetal anomaly...
October 2009: Fertility and Sterility
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