keyword
MENU ▼
Read by QxMD icon Read
search

Choroid plexus carcinoma

keyword
https://www.readbyqxmd.com/read/27899174/concurrent-gliosarcoma-and-choroid-plexus-carcinoma-in-a-cow
#1
A Ortloff, J Neumann, O Illanes
Brain tumours in cattle are uncommon and the spontaneous development of primary brain tumours of different histological types is rare in both man and animals. In man, multiple concurrent primary tumours of different types are occasionally described. We report the rare simultaneous occurrence of two different primary brain tumours, gliosarcoma and choroid plexus carcinoma, diagnosed by microscopical and immunofluorescence evaluation in an 8-year-old cow with a 2-month history of neurological disease. Gliosarcoma is a rare variant of glioblastoma multiforme, characterized by the presence of malignant glial cells and mesenchymal tissue...
November 26, 2016: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/27551116/genome-wide-dna-methylation-analysis-reveals-epigenetic-dysregulation-of-microrna-34a-in-tp53-associated-cancer-susceptibility
#2
Nardin Samuel, Gavin Wilson, Mathieu Lemire, Badr Id Said, Youliang Lou, Weili Li, Diana Merino, Ana Novokmet, James Tran, Kim E Nichols, Jonathan L Finlay, Sanaa Choufani, Marc Remke, Vijay Ramaswamy, Florence M G Cavalli, Christine Elser, Lynn Meister, Michael D Taylor, Uri Tabori, Meredith Irwin, Rosanna Weksberg, Jonathan D Wasserman, Andrew D Paterson, Jordan R Hansford, Maria Isabel W Achatz, Thomas J Hudson, David Malkin
PURPOSE: Although the link between mutant TP53 and human cancer is unequivocal, a significant knowledge gap exists in clinically actionable molecular targets in Li-Fraumeni syndrome (LFS), a highly penetrant cancer predisposition syndrome associated with germline mutations in TP53. This study surveyed the epigenome to identify functionally and clinically relevant novel genes implicated in LFS. PATIENTS AND METHODS: We performed genome-wide methylation analyses of peripheral blood leukocyte DNA in germline TP53 mutation carriers (n = 72) and individuals with TP53 wild type in whom histologically comparable malignancies developed (n = 111)...
August 22, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/27496084/risks-of-first-and-subsequent-cancers-among-tp53-mutation-carriers-in-the-national-cancer-institute-li-fraumeni-syndrome-cohort
#3
Phuong L Mai, Ana F Best, June A Peters, Rosamma M DeCastro, Payal P Khincha, Jennifer T Loud, Renée C Bremer, Philip S Rosenberg, Sharon A Savage
BACKGROUND: Li-Fraumeni syndrome (LFS) is an autosomal dominant cancer predisposition syndrome characterized by a very high lifetime cancer risk and an early age at diagnosis of a wide cancer spectrum. Precise estimates for the risk of first and subsequent cancers are lacking. METHODS: The National Cancer Institute's Li-Fraumeni Syndrome Study includes families meeting the diagnostic criteria for LFS or Li-Fraumeni-like syndrome, and individuals with a germline TP53 mutation, choroid plexus carcinoma, adrenocortical carcinoma, or ≥3 cancers...
December 1, 2016: Cancer
https://www.readbyqxmd.com/read/27372242/disseminated-choroid-plexus-papillomas-in-adults-a-case-series-and-review-of-the-literature
#4
Marwah M Abdulkader, Nassir H Mansour, Jamie J Van Gompel, Gregory A Bosh, Edward J Dropcho, Jose M Bonnin, Aaron A Cohen-Gadol
Choroid plexus papillomas (CPPs) are uncommon, usually intraventricular, low-grade tumors, accounting for less than 1% of all intracranial neoplasms and 2-4% of brain tumors in children. Dissemination of CPPs to multiple levels of the neuraxis has been seldom observed. Thus far, only 26 adult patients have been reported in the English language literature. With some exceptions, disseminated CPPs have been observed in adults and involved multiple sites along the cerebrospinal fluid pathways. Occasionally, intraparenchymal extension has been documented, and secondary involvement of the suprasellar region has been reported in only five patients...
October 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27299432/infant-brain-tumours-a-tale-of-two-cities
#5
Satyashiva Munjal, Uttara Chatterjee, Matthieu Vinchon, Sandip Chatterjee
INTRODUCTION: Infantile brain tumours (age < 1 year) are increasingly being diagnosed due to advances in prenatal and perinatal diagnostic imaging. We present here our retrospective study of 64 infant brain tumours that brings to the fore the epidemiology, clinical presentation, pathology and outcome of this unique subset of paediatric brain tumours presenting to two tertiary referral centres in Kolkata in India and Lille in France between the years 1999 and 2014. METHODS: Data was retrospectively collected from Kolkata (n = 30) and Lille (n = 34) for patients presenting with infant brain tumours and analysed for factors such as age at presentation, clinical features, gender, location of tumour, pathology, management and outcome...
September 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27229317/nherf1-ebp50-and-nf2-as-diagnostic-markers-for-choroid-plexus-tumors
#6
Maria-Magdalena Georgescu, Bret C Mobley, Brent A Orr, Ping Shang, Norman L Lehman, Xiaoping Zhu, Thomas J O'Neill, Veena Rajaram, Kimmo J Hatanpaa, Charles F Timmons, Jack M Raisanen
The adaptor protein NHERF1 (Na/H exchanger-3 regulatory factor-1) and its associated ezrin-radixin-moesin-merlin/neurofibromin-2 (ERM-NF2) family proteins are required for epithelial morphogenesis and have been implicated in cancer progression. NHERF1 is expressed in ependymal cells and constitutes a highly sensitive diagnostic marker for ependymoma, where it labels membrane polarity structures. Since NHERF1 and ERM-NF2 proteins show polarized expression in choroid plexus (CP) cells, we tested their diagnostic utility in CP neoplasms...
2016: Acta Neuropathologica Communications
https://www.readbyqxmd.com/read/27216721/kir7-1-immunoreactivity-in-canine-choroid-plexus-tumors
#7
Eun Ju Choi, Erica A Sloma, Andrew D Miller
Choroid plexus neoplasms are uncommon brain tumors in dogs. Choroid plexus carcinomas often spread diffusely throughout the ventricular system and subarachnoid space and, in aggressive forms, can mimic histologic patterns of other carcinomas, including being embedded in a desmoplastic reaction. Although choroid plexus tumors (CPTs) heterogeneously express pan-cytokeratin, little is known about other markers to identify choroid plexus and their associated tumors. Kir7.1, an inward-rectifier potassium channel, is reported to have high diagnostic utility in human neuropathology to distinguish CPTs from other primary brain tumors and cerebral metastases...
July 2016: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/26943652/selective-expression-of-transthyretin-in-subtypes-of-lung-cancer
#8
Shuai Hao, Suozhu Sun, Xueyuan Xiao, Dacheng He, Liyun Liu
Transthyretin (TTR) is expressed primarily in liver, choroid plexus of brain and pancreatic islet A and B cells. It is also synthesized in some endocrine tumors. In the present study, the protein expression of TTR in lung cancer tissues and cell lines was investigated by western blot. The mRNA expression of TTR in 24 pairs of frozen lung cancer tissues was examined by RT-PCR. The specific expression and cellular distribution of TTR were also evaluated in 104 paraffin-embedded lung cancer samples and 3 normal lung tissues by immunohistochemistry...
June 2016: Journal of Molecular Histology
https://www.readbyqxmd.com/read/26690880/decreased-foxj1-expression-and-its-ciliogenesis-programme-in-aggressive-ependymoma-and-choroid-plexus-tumours
#9
Malak S Abedalthagafi, Michael P Wu, Parker H Merrill, Ziming Du, Terri Woo, Shu-Hsien Sheu, Shelley Hurwitz, Keith L Ligon, Sandro Santagata
Well-differentiated human cancers share transcriptional programmes with the normal tissue counterparts from which they arise. These programmes broadly influence cell behaviour and function and are integral modulators of malignancy. Here, we show that the master regulator of motile ciliogenesis, FOXJ1, is highly expressed in cells along the ventricular surface of the human brain. Strong expression is present in cells of the ependyma and the choroid plexus as well as in a subset of cells residing in the subventricular zone...
March 2016: Journal of Pathology
https://www.readbyqxmd.com/read/26478476/choroid-plexus-tumors-experience-of-10-cases-with-special-references-to-adult-cases
#10
Manoj Bohara, Masashi Hirabaru, Shingo Fujio, Michiyo Higashi, Hajime Yonezawa, Prasanna Karki, Ryosuke Hanaya, Hirofumi Hirano, Hiroshi Tokimura, Kazunori Arita
Choroid plexus tumors (CPTs) are rare intraventricular neoplasms accounting for about 0.3-0.6% of all intracranial tumors. This retrospective study on CPTs presents clinico-pathological features and management strategies based on a 20-year single-institutional experience. This series included 10 consecutive patients with pathologically proven CPTs; 5 choroid plexus papillomas (CPPs), 3 atypical CPPs (ACPPs), and 2 choroid plexus carcinomas (CPCs). Their clinical, radiological, and histopathological features as well as management including follow-up studies were reviewed...
2015: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/26452166/occurrence-of-neuroblastoma-among-tp53-p-r337h-carriers
#11
Ana Luiza Seidinger, Fernanda Paschoal Fortes, Maria José Mastellaro, Izilda Aparecida Cardinalli, Lilian Girotto Zambaldi, Simone Santos Aguiar, José Andrés Yunes
The high incidence of adrenocortical tumors and choroid plexus carcinoma in children from South and Southeastern regions of Brazil is associated with the germline p.R337H mutation of TP53 gene. The concomitant occurrence of neuroblastoma and adrenocortical tumors in pediatric patients harboring the p.R337H mutation at our institution prompted us to investigate the putative association between p.R337H and pediatric neuroblastoma. Genomic DNA samples from 83 neuroblastoma patients referred to a single institution during the period of 2000-2014 were screened for the p...
2015: PloS One
https://www.readbyqxmd.com/read/26442551/solitary-metastasis-of-renal-cell-carcinoma-to-the-third-ventricle-mimicking-a-colloid-cyst-case-report
#12
Mete Karatay, Ender Koktekir, Yavuz Erdem, Haydar Celik, Mehmet Akif Bayar
Colloid cysts are the most common third ventricle lesions and metastasis to this area is rare. We presented a case of solitary metastasis from a renal cell carcinoma to the third ventricle choroid plexus mimicking a colloid cyst. A 53-year-old man, who had a history of renal cell carcinoma 12 years ago, was operated for single third ventricle lesion and hydrocephalus via a transcallosal approach. Total removal could not be performed due to intraoperative massive bleeding. Histological examination revealed a metastatic renal cell carcinoma...
2015: Turkish Neurosurgery
https://www.readbyqxmd.com/read/26439197/choroid-plexus-carcinoma-in-the-external-ventricle-of-an-adult
#13
LETTER
Pin Guo, Wanzhong Tang, Shifang Li, Huanting Li, Lei Cheng, Yugong Feng, Yanan Yu
No abstract text is available yet for this article.
October 2015: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/26248671/pre-operative-embolization-of-a-choroid-plexus-carcinoma-review-of-the-vascular-anatomy
#14
Lee-Anne Slater, Caitlin Hoffman, James Drake, Timo Krings
AIM: The purpose of this case is to highlight the benefits of preoperative embolization as well as to review the vascular anatomy that needs to be recognized in order to perform pre-operative embolization of choroid plexus tumors. METHOD: We achieve this by presenting the case of a 12-month-old female who had symptoms of raised intracranial pressure. MRI demonstrated a large vividly enhancing mass centered within the atria of the right lateral ventricle associated with hydrocephalus in keeping with a choroid plexus tumor...
March 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/26209253/-choroid-plexus-tumours-in-childhood-experience-in-sant-joan-de-d%C3%A3-u-hospital
#15
Clara Maria Del Río-Pérez, Mariona Suñol-Capella, Ofelia Cruz-Martinez, Gemma Garcia-Fructuoso
Choroid plexus tumours are rare, with a peak incidence in the first two years of life. The most common location is the lateral ventricle in children, while in adults it is the fourth ventricle. The most common clinical manifestation is the signs and symptoms of intracranial hypertension. They are histologically classified as plexus papilloma, atypical plexus papilloma, and plexus carcinoma. A review is presented on choroid plexus tumours treated in the Hospital Sant Joan de Déu between 1980 and 2014. A total of 18 patients have been treated...
March 2016: Neurocirugía
https://www.readbyqxmd.com/read/26161225/choroid-plexus-carcinoma-in-adults-an-extremely-rare-case
#16
Selcuk Ozdogan, Yusuf Emrah Gergin, Sinem Gergin, Ozgur Senol, Mehmet Tiryaki, Necati Tatarli, Tufan Hicdonmez
Choroid plexus tumors are rare intraventricular papillary neoplasms derived from choroid plexus epithelium, which account for approximately 2% to 4% of intracranial tumors in children and 0.5% in adults. Almost all choroid plexus carcinomas are seen in children and are extremely rare in adults. Headache, diplopia, and ataxia are the most common symptoms usually caused by mechanical obstruction of cerebrospinal fluid flow followed by hydrocephalus, regardless of tumor location. We present an illustrative case with 73 years old male patient who was consulted with headache to our neurosurgery department...
2015: Pan African Medical Journal
https://www.readbyqxmd.com/read/26026631/bilateral-choroid-plexus-metastasis-from-papillary-thyroid-carcinoma-case-report-and-review-of-the-literature
#17
REVIEW
Guive Sharifi, Mehrdad Hosseinzadeh Bakhtevari, Mohsen Alghasi, Masood Asghsri Nosari, Ramin Rahmanzade, Omidvar Rezaei
BACKGROUND: Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. It has an indolent clinical course and favorable prognosis. Brain metastasis is uncommon and complicates about 0.1%-5% of PTCs. Metastasis to the choroid plexus of the lateral ventricles has been reported in 7 cases of thyroid malignancies, all of which were unilateral. METHODS: We report a case of a 52-year-old woman with a history of PTC who presented with severe headache, nausea and vomiting, right hemiparesis, and speech disturbance...
October 2015: World Neurosurgery
https://www.readbyqxmd.com/read/26021621/choroid-plexus-neoplasms-toward-a-distinction-between-carcinoma-and-papilloma-using-arterial-spin-labeling
#18
V Dangouloff-Ros, D Grevent, M Pagès, T Blauwblomme, R Calmon, C Elie, S Puget, C Sainte-Rose, F Brunelle, P Varlet, N Boddaert
Pediatric choroid plexus papillomas and carcinomas are highly vascularized neoplasms, which are difficult to distinguish with conventional imaging. We aimed to analyze the diagnostic accuracy of PWI, by using both pseudocontinuous arterial spin-labeling and DSC-PWI. We reviewed the PWI of 13 children with choroid plexus neoplasms (7 papillomas and 6 carcinomas). We quantified CBF, relative CBF, and relative CBV in each lesion and compared papillomas and carcinomas. Relative CBF values by using arterial spin-labeling were significantly higher for carcinomas (P = ...
September 2015: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/26014290/revisiting-li-fraumeni-syndrome-from-tp53-mutation-carriers
#19
Gaëlle Bougeard, Mariette Renaux-Petel, Jean-Michel Flaman, Camille Charbonnier, Pierre Fermey, Muriel Belotti, Marion Gauthier-Villars, Dominique Stoppa-Lyonnet, Emilie Consolino, Laurence Brugières, Olivier Caron, Patrick R Benusiglio, Brigitte Bressac-de Paillerets, Valérie Bonadona, Catherine Bonaïti-Pellié, Julie Tinat, Stéphanie Baert-Desurmont, Thierry Frebourg
PURPOSE: The aim of the study was to update the description of Li-Fraumeni syndrome (LFS), a remarkable cancer predisposition characterized by extensive clinical heterogeneity. PATIENTS AND METHODS: From 1,730 French patients suggestive of LFS, we identified 415 mutation carriers in 214 families harboring 133 distinct TP53 alterations and updated their clinical presentation. RESULTS: The 322 affected carriers developed 552 tumors, and 43% had developed multiple malignancies...
July 20, 2015: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/25998405/concurrent-gain-of-oncogenes-drives-choroid-plexus-carcinoma
#20
(no author information available yet)
TAF12, NFYC, and RAD54L are oncogenes required to initiate and maintain choroid plexus carcinoma (CPC).
July 2015: Cancer Discovery
keyword
keyword
18207
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"