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Spectral CT

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https://www.readbyqxmd.com/read/27918709/spectral-photon-counting-ct-initial-experience-with-dual-contrast-agent-k-edge-colonography
#1
Daniela Muenzel, Daniel Bar-Ness, Ewald Roessl, Ira Blevis, Matthias Bartels, Alexander A Fingerle, Stefan Ruschke, Philippe Coulon, Heiner Daerr, Felix K Kopp, Bernhard Brendel, Axel Thran, Michal Rokni, Julia Herzen, Loic Boussel, Franz Pfeiffer, Roland Proksa, Ernst J Rummeny, Philippe Douek, Peter B Noël
Purpose To investigate the feasibility of using spectral photon-counting computed tomography (CT) to differentiate between gadolinium-based and nonionic iodine-based contrast material in a colon phantom by using the characteristic k edge of gadolinium. Materials and Methods A custom-made colon phantom was filled with nonionic iodine-based contrast material, and a gadolinium-filled capsule representing a contrast material-enhanced polyp was positioned on the colon wall. The colon phantom was scanned with a preclinical spectral photon-counting CT system to obtain spectral and conventional data...
December 2, 2016: Radiology
https://www.readbyqxmd.com/read/27916593/clinical-application-of-dual-energy-spectral-computed-tomography-in-detecting-cholesterol-gallstones-from-surrounding-bile
#2
Chuang-Bo Yang, Shuang Zhang, Yong-Jun Jia, Hai-Feng Duan, Guang-Ming Ma, Xi-Rong Zhang, Yong Yu, Tai-Ping He
RATIONALE AND OBJECTIVE: This study aimed to investigate the clinical value of spectral computed tomography (CT) in the detection of cholesterol gallstones from surrounding bile. MATERIALS AND METHODS: This study was approved by the institutional review board. The unenhanced spectral CT data of 24 patients who had surgically confirmed cholesterol gallstones were analyzed. Lipid concentrations and CT numbers were measured from fat-based material decomposition image and virtual monochromatic image sets (40-140 keV), respectively...
December 1, 2016: Academic Radiology
https://www.readbyqxmd.com/read/27911354/a-spectral-interior-ct-by-a-framelet-based-reconstruction-algorithm
#3
Yingmei Wang, Ge Wang, Shuwei Mao, Wenxiang Cong, Zhilong Ji, Jian-Feng Cai, Yangbo Ye
Reducing radiation dose is an important goal in medical computed tomography (CT), for which interior tomography is an effective approach. There have been interior reconstruction algorithms for monochromatic CT, but in reality, X-ray sources are polychromatic. Using a polychromatic acquisition model and motivated by framelet-based image processing algorithms, in this paper, we propose an interior reconstruction algorithm to obtain an image with spectral information assuming only one scan with a current energy-integrating detector...
November 22, 2016: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/27905337/choroidal-thickness-evaluation-of-healthy-eyes-central-serous-chorioretinopathy-and-fellow-eyes-using-spectral-domain-optical-coherence-tomography-in-indian-population
#4
Supriya Arora, Richa Pyare, Preethi Sridharan, Tarun Arora, Meenakshi Thakar, Basudeb Ghosh
AIM: The purpose of this study is to establish a normative database of subfoveal choroidal thickness (CT) in healthy young Indians using spectral domain optical coherence tomography (SD OCT). Evaluation and comparison of CT of central serous chorioretinopathy (CSC) and fellow eyes were also performed. MATERIALS AND METHODS: This was a prospective, cross-sectional, and observational study. It included 112 normal eyes of 112 healthy volunteers who had no evidence of ocular or systemic disease, 84 CSC eyes with acute, treatment-naïve CSC, and 69 fellow eyes with no evidence of neurosensory detachment or pigment epithelium detachment on SD OCT...
October 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27880738/an-adaptive-reconstruction-algorithm-for-spectral-ct-regularized-by-a-reference-image
#5
Miaoshi Wang, Yanbo Zhang, Rui Liu, Shuxu Guo, Hengyong Yu
The photon counting detector based spectral CT system is attracting increasing attention in the CT field. However, the spectral CT is still premature in terms of both hardware and software. To reconstruct high quality spectral images from low-dose projections, an adaptive image reconstruction algorithm is proposed that assumes a known reference image (RI). The idea is motivated by the fact that the reconstructed images from different spectral channels are highly correlated. If a high quality image of the same object is known, it can be used to improve the low-dose reconstruction of each individual channel...
December 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27880736/experimental-validation-of-a-multi-energy-x-ray-adapted-scatter-separation-method
#6
A Sossin, V Rebuffel, J Tabary, J M Létang, N Freud, L Verger
Both in radiography and computed tomography (CT), recently emerged energy-resolved x-ray photon counting detectors enable the identification and quantification of individual materials comprising the inspected object. However, the approaches used for these operations require highly accurate x-ray images. The accuracy of the images is severely compromised by the presence of scattered radiation, which leads to a loss of spatial contrast and, more importantly, a bias in radiographic material imaging and artefacts in CT...
December 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27875364/attenuation-of-choroidal-thickness-in-patients-with-alzheimer-disease-evidence-from-an-italian-prospective-study
#7
Alessandro Trebbastoni, Michela Marcelli, Fabiana Mallone, Fabrizia D'Antonio, Letizia Imbriano, Alessandra Campanelli, Carlo de Lena, Magda Gharbiya
INTRODUCTION: To compare the 12-month choroidal thickness (CT) change between Alzheimer disease (AD) patients and normal subjects. METHODS: In this prospective, observational study, 39 patients with a diagnosis of mild to moderate AD and 39 age-matched control subjects were included. All the subjects underwent neuropsychological (Mini Mental State Examination, Alzheimer disease Assessment Scale-Cognitive Subscale, and the Clinical Dementia Rating Scale) and ophthalmological evaluation, including spectral domain optical coherence tomography, at baseline and after 12 months...
November 21, 2016: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/27867167/evaluation-of-fat-quantification-in-the-liver-using-dual-energy-ct
#8
Shunsuke Itaya, Takeshi Matsui, Tetsuya Kamiyama, Hiroyuki Yoshino
BACKGROUND AND PURPOSE: Recently, the number of patients with nonalcoholic fatty liver disease (NAFLD) has been increasing, and some of them progresses to cirrhosis and hepatocellular carcinoma. Dual energy CT allows the discrimination of substance using monochromatic image (MI), and steatosis exhibit specifically the CT value of each energy level. The purpose is to evaluate the fat quantification in the liver using spectral HU curve and CT value compare to a conventional image diagnosis...
2016: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/27866516/-gsi-quantitative-parameters-preoperative-diagnosis-of-metastasis-lymph-nodes-in-lung-cancer
#9
Fengfeng Yang, Jie Dong, Xiaolong Yan, Xiuting Wang, Xiaojiao Fu, Tong Zhang
BACKGROUND: Mediastinal involvement in lung cancer is an important prognostic factor affecting survival, and accurate staging of the mediastinum lymph node correctly identifies patients who can benefit the most from surgery. The aim of this study is to investigate the value of dual-energy spectral computed tomography (DEsCT) imaging in differentiating metastatic from non-metastatic lymph nodes in lung cancer. METHODS: Forty-eight patients with non-small cell lung cancer (NSCLC) underwent arterial (AP) and portal venous (PP) phase contrast-enhanced DEsCT imaging followed by surgical treatment...
November 20, 2016: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/27864600/comparison-of-true-unenhanced-and-virtual-unenhanced-vue-attenuation-values-in-abdominopelvic-single-source-rapid-kilovoltage-switching-spectral-ct
#10
Amir A Borhani, Matthew Kulzer, Negaur Iranpour, Anish Ghodadra, Mark Sparrow, Alessandro Furlan, Mitchell E Tublin
OBJECTIVE: To assess the agreement between the true non-contrast (TNC) attenuation values of intra-abdominal structures and attenuation values obtained on virtual-unenhanced (VUE) images based on rapid kVp-switching dual-energy CT. The effects of contrast phase and patient characteristics (e.g., BMI, hematocrit, hemoglobin content) on VUE values were also investigated. METHODS: Ninety four patients who underwent triphasic abdominal CT (liver mass protocol, n = 47; pancreas mass protocol, n = 47) between August 2014 and May 2015 were retrospectively reviewed...
November 18, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27824666/a-comparison-of-the-image-quality-and-radiation-dose-with-routine-computed-tomography-and-the-latest-gemstone-spectral-imaging-combination-of-different-scanning-protocols-in-computed-tomography-angiography-of-the-kidney
#11
Yong-Xia Zhao, Hong-Na Suo, Zi-Wei Zuo, Ying-Jin Xu, Jin Chang
OBJECTIVE: The objective of our study was to compare the image quality and radiation dose of computed tomography angiography (CTA) of the kidney in patients with different body mass indexes using routine CT and the latest gemstone spectral imaging (GSI) combination of different scanning protocols with the adaptive statistical iterative reconstruction 2.0 algorithm. METHODS: A total of 90 patients who had undergone a CTA of the kidney were divided into 3 groups (A, B, and C), with 30 patients in each group...
November 7, 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27816644/new-cobalt-ii-and-nickel-ii-complexes-of-benzyl-carbazate-schiff-bases-syntheses-crystal-structures-in-vitro-dna-and-hsa-binding-studies
#12
Palanivelu Nithya, Sannasi Helena, Jim Simpson, Malaichamy Ilanchelian, Aathi Muthusankar, Subbiah Govindarajan
In the present study, new Schiff base complexes with the composition [M(NCS)2(L1)2]·nH2O, where M=Co (n=0) (1) and Ni (n=2) (2); [M(NCS)2(L2)2], M=Co (3) and Ni (4) as well as [M(NCS)2(L3)2], M=Co (5) and Ni (6); (L1=benzyl 2-(propan-2-ylidene)hydrazinecarboxylate, L2=benzyl 2-(butan-2-ylidene)hydrazinecarboxylate and L3=benzyl 2-(pentan-3-ylidene)hydrazinecarboxylate) have been synthesized by a template method. The complexes were characterised by analytical methods, spectroscopic studies, thermal and X-ray diffraction techniques...
October 24, 2016: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/27807391/arterial-wall-perfusion-measured-with-photon-counting-spectral-x-ray-ct
#13
Steven M Jorgensen, Mark J Korinek, Andrew J Vercnocke, Jill L Anderson, Ahmed Halaweish, Shuai Leng, Cynthia H McCollough, Erik L Ritman
Early atherosclerosis changes perfusion of the arterial wall due to localized proliferation of the vasa vasorum. When contrast agent passes through the artery, some enters the vasa vasorum and increases radiopacity of the arterial wall. Technical challenges to detecting changes in vasa vasorum density include the thin arterial wall, partial volume averaging at the arterial lumen/wall interface and calcification within the wall. We used a photon-counting spectral CT scanner to study carotid arteries of anesthetized pigs and micro-CT of these arteries to quantify vasa vasorum density...
August 28, 2016: Proceedings of SPIE
https://www.readbyqxmd.com/read/27805190/a-study-of-dna-bsa-interaction-and-catalytic-potential-of-oxidovanadium-v-complexes-with-ono-donor-ligands
#14
Subhashree P Dash, Alok K Panda, Sarita Dhaka, Sagarika Pasayat, Ashis Biswas, Mannar R Maurya, Paresh Kumar Majhi, Aurélien Crochet, Rupam Dinda
The study of DNA/BSA interaction and the catalytic potential of four mononuclear oxidoalkoxido vanadium(v) [V(V)O(L(1-4))OEt] (1-4) and one dinuclear oxidoalkoxido mixed-ligand vanadium(v) [{VO(L(2))OEt}2(Q)]{Q = 4,4'-bipyridine}(5) complexes, with tridentate binegative aroylazine ligands are reported [where H2L(1) = anthranylhydrazone of 2-hydroxy-1-napthaldehyde, H2L(2) = salicylhydrazone of 2-hydroxy-1-napthaldehyde, H2L(3) = benzoylhydrazone of 2-hydroxy-1-acetonaphthone, H2L(4) = anthranylhydrazone of 2-hydroxy-1-acetonaphthone]...
November 2, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/27803734/usefulness-of-spectral-computed-tomography-for-evaluation-of-intestinal-activity-and-severity-in-ileocolonic-crohn-s-disease
#15
Jiang Chen Peng, Qi Feng, Jiong Zhu, Jun Shen, Yu Qi Qiao, Jian Rong Xu, Zhi Hua Ran
BACKGROUND: Assessment of intestinal activity and severity of Crohn's disease (CD) is crucial to guide treatment. In this study, we aimed to investigate the accuracy of spectral computed tomography (CT) in this assessment and make a comparison with conventional CT. METHODS: A total of 50 patients with ileocolonic CD underwent spectral CT scanning. Conventional CT and spectral CT images were reconstructed. Endoscopic lesions were classified as absent, mild lesions and severe lesions...
November 2016: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/27795606/evaluation-of-a-photon-counting-medipix3rx-czt-spectral-x-ray-detector
#16
Steven M Jorgensen, Andrew J Vercnocke, David S Rundle, Philip H Butler, Cynthia H McCollough, Erik L Ritman
We assessed the performance of a cadmium zinc telluride (CZT)-based Medipix3RX x-ray detector as a candidate for micro-computed tomography (micro-CT) imaging. This technology was developed at CERN for the Large Hadron Collider. It features an array of 128 by 128, 110 micrometer square pixels, each with eight simultaneous threshold counters, five of which utilize real-time charge summing, significantly reducing the charge sharing between contiguous pixels. Pixel response curves were created by imaging a range of x-ray intensities by varying x-ray tube current and by varying the exposure time with fixed x-ray current...
August 28, 2016: Proceedings of SPIE
https://www.readbyqxmd.com/read/27794220/dna-interaction-antimicrobial-studies-of-newly-synthesized-copper-ii-complexes-with-2-amino-6-trifluoromethoxy-benzothiazole-schiff-base-ligands
#17
Aveli Rambabu, Marri Pradeep Kumar, Somapangu Tejaswi, Narendrula Vamsikrishna, Shivaraj
Four novel Schiff base ligands, L(1) (1-((E)-(6-(trifluoromethoxy)benzo[d]thiazol-2-ylimino)methyl)naphthalen-2-ol, C19H11F3N2O2S), L(2) (3-((E)-(6-(trifluoromethoxy)benzo[d]thiazol-2-ylimino)methyl)benzene-1,2-diol, C15H9F3N2O3S), L(3) (2-((E)-(6-(trifluoromethoxy)benzo[d]thiazol-2-ylimino)methyl)-5-methoxyphenol, C16H11F3N2O3S) and L(4) (2-((E)-(6-(trifluoromethoxy)benzo[d]thiazol-2-ylimino)methyl)-4-bromophenol, C15H8BrF3N2O2S) and their binary copper(II) complexes 1 [Cu(L(1))2], 2 [Cu(L(2))2], 3 [Cu(L(3))2] and 4 [Cu(L(4))2] have been synthesized and characterized by elemental analysis, (1)H NMR, (13)C NMR, ESI mass, FT-IR, ESR, UV-Visible, magnetic susceptibility, TGA, SEM and powder XRD studies...
October 24, 2016: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/27788724/-value-of-spectral-ct-based-quantitative-analysis-in-differential-diagnosis-of-liver-cancer-and-liver-abscess
#18
H Q Gao, C H Hu, Y X Yu, S Hu, C Shi, X M Wang, L Guo
Objective: To investigate the value of spectral CT-based quantitative analysis in the differential diagnosis of liver cancer and liver abscess. Methods: A total of 70 patients with space-occupying lesions in the liver(45 with liver cancer and 25 with liver abscess)underwent spectral CT scans to obtain spectral images in the arterial phase and portal venous phase. The solid constituents of lesions and the iodine and water concentrations in necrotic or cystic parts of lesions, normal hepatic tissue, and abdominal aorta in the arterial phase and portal venous phase were measured, and the normalized iodine concentration(NIC)and lesion-to-normal hepatic tissue ratio(LNR)of iodine concentration were calculated...
September 20, 2016: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/27777787/practical-alignment-method-for-x-ray-spectral-measurement-in-micro-ct-system-based-on-3d-printing-technology
#19
Liqiang Ren, Di Wu, Yuhua Li, Bin Zheng, Yong Chen, Kai Yang, Hong Liu
This study presents a practical alignment method for X-ray spectral measurement in a rotating gantry based micro-computed tomography (micro-CT) system using three-dimensional (3D) printing technology. In order to facilitate the spectrometer placement inside the gantry, supporting structures including a cover and a stand were dedicatedly designed and printed using a 3D printer. According to the relative position between the spectrometer and the stand, the upright projection of the spectrometer collimator onto the stand was determined and then marked by a tungsten pinhole...
June 2016: Biomedical Physics & Engineering Express
https://www.readbyqxmd.com/read/27768006/application-of-low-concentration-contrast-medium-in-spectral-ct-imaging-for-ct-portal-venography
#20
Yongxia Zhao, Yanmin Wu, Ziwei Zuo, Hongna Suo, Sisi Zhao, Jun Han, Xian Chang, Shujie Cheng
OBJECTIVE: To investigate the effect of low-concentration contrast medium on spectral computed tomography (CT) image quality for portal venography CT. METHODS: 150 patients with suspected portal diseases were divided into three groups and had spectral CT examination using a GE Discovery CT 750 HD scanner. The patients in three groups were injected with different concentrations of iodine (350 mgI/mL, 315 mgI/mL and 280 mgI/mL) at an injection rate of 4.0-5...
October 21, 2016: Journal of X-ray Science and Technology
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