keyword
MENU ▼
Read by QxMD icon Read
search

Spectral CT

keyword
https://www.readbyqxmd.com/read/28810555/evaluation-of-rat-c6-malignant-glioma-using-spectral-computed-tomography
#1
Jianli Liu, Junlin Zhou, Jie Li, Lingyan Zhang, Peili Zhang, Bin Liu
To investigate the use of multi-parameter spectral computed tomography (CT) for the evaluation of rat C6 glioma, 15 male Wistar rats were seeded with C6 glioma cells into the right basal ganglia and scanned 12 days later using spectral CT. Brain sections corresponding to scanned regions were immunostained for proliferation marker protein Ki67 (Ki67). Pearson's correlation coefficients between spectral CT parameters and Ki67 expression were determined. Thirteen rats survived 12 days and developed tumors. Optimal contrast-to-noise ratio achieved was 65 keV...
August 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28801615/choroidal-remodeling-in-age-related-macular-degeneration-and-polypoidal-choroidal-vasculopathy-a-12-month-prospective-study
#2
Daniel Shu Wei Ting, Yasuo Yanagi, Rupesh Agrawal, Hwei Yee Teo, Sophia Seen, Ian Yew San Yeo, Ranjana Mathur, Choi Mun Chan, Shu Yen Lee, Edmund Yick Mun Wong, Doric Wong, Tien Yin Wong, Gemmy Chui Ming Cheung
Choroid thinning occurs in age-related macular degeneration (AMD). However, it remains unclear whether the reduction is due to reduction in choroidal vessels or shrinkage of choroidal stroma, or both. The purpose of this study was to evaluate the changes of the choroidal vascular and stromal area in 118 patients with typical AMD (t-AMD) and polypoidal choroidal vasculopathy (PCV) over a 12-month period. We used spectral-domain optical coherence tomography (SD-OCT) with enhanced depth imaging (EDI) mode to measure the subfoveal choroidal thickness (CT), central retinal thickness (CRT) and choroidal vascularity index (CVI - ratio of luminal area to total choroidal area)...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28796078/preliminary-application-of-multiple-parameters-spectral-ct-in-the-diagnosis-of-ovarian-cancer
#3
Tao Pang, Zhao-di Liu, Kai Deng, Cheng-Qi Zhang, Guang-Li Wang
The aim of the study was to evaluate the effectiveness of spectral CT in the diagnosis of ovarian cancer. We retrospectively analyzed the data of 22 patients with spectral CT enhanced scan. The patients were divided into 2 groups: ovarian cancer group (n = 11) and benign tumor group (n = 11), according to the pathologic results. CT values at 40 keV, iodine concentration (IC), water concentration (WC) and spectral curve slope (λHU) of arterial phase and venous phase in the tumors of 2 groups were measured with gemstone spectral imaging (GSI) post-processing software...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28783629/low-dose-contrast-enhanced-breast-ct-using-spectral-shaping-filters-an-experimental-study
#4
Andrey Makeev, Stephen J Glick
Iodinated contrast-enhanced x-ray imaging of the breast has been studied with various modalities including, fullfield digital mammography (FFDM), digital breast tomosynthesis (DBT), and dedicated breast CT (BCT). Contrast imaging with breast CT has a number of advantages over FFDM and DBT including the lack of breast compression, and generation of fully isotropic, three-dimensional reconstructions. Nonetheless, for breast CT to be considered as a viable tool for routine clinical use, it would be desirable to reduce radiation dose...
August 2, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28780617/the-association-of-helicobacter-pylori-with-choroidal-and-retinal-nerve-fiber-layer-thickness
#5
Mehmet Erol Can, Fatma Efe Kaplan, Mehmet Murat Uzel, Hasan Kiziltoprak, Mustafa Cagri Ergun, Mustafa Koc, Gülcin Simsek
PURPOSE: To investigate the effect of Helicobacter pylori (H. pylori) infection on choroidal thickness (CT) and retinal nerve fiber layer thickness (RNFLT). METHODS: The study included 25 patients with H. pylori infection and 25 healthy individuals as the control group. Helicobacter pylori patients were classified as the pre-treatment (Group 1; n: 25) and the post-treatment (Group 2; n: 25). RNFLT and CT were measured before and after treatment of H. pylori infection, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (Spectralis, Heidelberg Engineering, Heidelberg, Germany)...
August 5, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28780455/microwave-assisted-synthesis-of-mixed-ligands-organotin-iv-complexes-of-1-10-phenanthroline-and-l-proline-physicochemical-characterization-dft-calculations-chemotherapeutic-potential-validation-by-in-vitro-dna-binding-and-nuclease-activity
#6
Mala Nath, Mridula, Ranjana Kumari
Diorganotin(IV) and triphenyltin(IV) derivatives of L-proline (HPro) having general formula R2Sn(Pro)2 (R=n-Bu (1), Ph (2)) and Ph3Sn(Pro) (3), respectively, and the mixed ligands di-/triorganotin(IV) derivatives of L-proline and 1,10-phenanthroline (phen) with general formula [R2Sn(Pro)(Phen)Cl] and [R3Sn(Pro)(Phen)] (where R=Me (4 and 7), n-Bu (5 and 8), Ph (6 and 9)), respectively, have been synthesized by microwave-assisted method and characterized by elemental analysis, IR, NMR ((1)H, (13)C and (119)Sn) and DART-mass spectral studies...
July 29, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28756153/hybrid-pharmacophore-approach-for-bio-relevant-di-imines-based-homobimetallic-complexes-incorporating-functionalized-dicarboxylates-as-co-ligands-synthesis-spectral-and-structural-activity-dependent-biological-insights-in-vitro-dna-and-hsa-binding-antioxidant
#7
Mohammad Shakir, Summaiya Hanif, Md Fazle Alam, Mohd Farhan, Hina Younus
Synthesis of bio-efficient homobimetallic complexes, [Cu2(L(1))2(dipic)](NO3)2.3H2O (1), [Zn2(L(1))2(dipic)](NO3)2.4H2O (2), [Cu2(L(2))2(oxa)](NO3)2.4H2O (3) and [Zn2(L(2))2(oxa)] (NO3)2.5H2O (4) was carried out using Schiff bases [(N(1)E,N(2)E)-N(1),N(2)-bis(5-chlorothiophen-2-ylmethylene)-4-chlorobenzene-1,2-diamine; L(1)] and [(N(1)E,N(2)E)-N(1),N(2)-bis(5-chlorofuran-2-ylmethylene)-4-chlorobenzene-1,2-diamine; L(2)] as main ligands and dicarboxylate moieties of 2,6-pyridine dicarboxylic acid (H2-dipic) and oxalic acid (H2-oxa) as co-ligands, respectively in order to apprehend their structure activity relationships on the basis of pharmacophore hybrid approach...
July 24, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28752310/impact-of-metal-artifact-reduction-software-on-image-quality-of-gemstone-spectral-imaging-dual-energy-cerebral-ct-angiography-after-intracranial-aneurysm-clipping
#8
Vincent Dunet, Martine Bernasconi, Steven David Hajdu, Reto Antoine Meuli, Roy Thomas Daniel, Jean-Baptiste Zerlauth
PURPOSE: We aimed to assess the impact of metal artifact reduction software (MARs) on image quality of gemstone spectral imaging (GSI) dual-energy (DE) cerebral CT angiography (CTA) after intracranial aneurysm clipping. METHODS: This retrospective study was approved by the institutional review board, which waived patient written consent. From January 2013 to September 2016, single source DE cerebral CTA were performed in 45 patients (mean age: 60 ± 9 years, male 9) after intracranial aneurysm clipping and reconstructed with and without MARs...
July 27, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28749176/quantifying-potential-reduction-in-contrast-dose-with-monoenergetic-images-synthesized-from-duallayer-detector-spectral-ct
#9
Derek S Tsang, Thomas E Merchant, Sophie E Merchant, Hanna Smith, Yoad Yagil, Chia-Ho Hua
OBJECTIVES: To estimate the potential dose reduction in iodinated contrast when interpreting monoenergetic images from spectral CT. METHODS: 51 pediatric patients received contrast-enhanced CT simulation for radiation therapy using a single-source, dual-layer detector spectral CT. The contrast-to-noise ratios (CNR) of blood vessels were measured relative to surrounding soft tissue. CNRs on monoenergetic 40-70 keV images were compared with polychromatic 120 kVp images...
July 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28735495/neuroanatomical-and-resting-state-eeg-power-correlates-of-central-hearing-loss-in-older-adults
#10
Nathalie Giroud, Sarah Hirsiger, Raphaela Muri, Andrea Kegel, Norbert Dillier, Martin Meyer
To gain more insight into central hearing loss, we investigated the relationship between cortical thickness and surface area, speech-relevant resting state EEG power, and above-threshold auditory measures in older adults and younger controls. Twenty-three older adults and 13 younger controls were tested with an adaptive auditory test battery to measure not only traditional pure-tone thresholds, but also above individual thresholds of temporal and spectral processing. The participants' speech recognition in noise (SiN) was evaluated, and a T1-weighted MRI image obtained for each participant...
July 22, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28726669/spectral-performance-of-a-whole-body-research-photon-counting-detector-ct-quantitative-accuracy-in-derived-image-sets
#11
Shuai Leng, Wei Zhou, Zhicong Yu, Ahmed F Halaweish, Bernhard Krauss, Bernhard Schmidt, Lifeng Yu, Steffen Kappler, Cynthia H McCollough
Photon-counting computed tomography (PCCT) uses a photon counting detector to count individual photons and allocate them to specific energy bins by comparing photon energy to preset thresholds. This enables simultaneous multi-energy CT with a single source and detector. Phantom studies were performed to assess the spectral performance of a research PCCT scanner by assessing the accuracy of derived images sets. Specifically, we assessed the accuracy of iodine quantification in iodine map images and of CT number accuracy in virtual monoenergetic images (VMI)...
July 20, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28715327/joint-statistical-iterative-material-image-reconstruction-for-spectral-computed-tomography-using-a-semi-empirical-forward-model
#12
Korbinian Mechlem, Sebastian Ehn, Thorsten Sellerer, Eva Braig, Daniela Munzel, Franz Pfeiffer, Peter B Noel
By acquiring tomographic measurements with several distinct photon energy spectra, spectral computed tomography (spectral CT) is able to provide additional material-specific information compared to conventional CT. This information enables the generation of material selective images, which have found various applications in medical imaging. However, material decomposition typically leads to noise amplification and a degradation of the signal-to-noise ratio. This is still a fundamental problem of spectral CT, especially for low-dose medical applications...
July 13, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28711211/advanced-tissue-characterization-and-texture-analysis-using-dual-energy-computed-tomography-horizons-and-emerging-applications
#13
REVIEW
Reza Forghani, Ashok Srinivasan, Behzad Forghani
In the last article of this issue, advanced analysis capabilities of DECT is reviewed, including spectral Hounsfield unit attenuation curves, virtual monochromatic images, material decomposition maps, tissue effective Z determination, and other advanced post-processing DECT tools, followed by different methods of analysis of the attenuation curves generated using DECT. The article concludes with exciting future horizons and potential applications, such as the use of the rich quantitative data in dual energy CT scans for texture or radiomic analysis and the use of machine learning methods for generation of prediction models using spectral data...
August 2017: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/28711205/dual-energy-computed-tomography-applications-for-the-evaluation-of-cervical-lymphadenopathy
#14
REVIEW
Ahmed M Tawfik, Andreas Michael Bucher, Thomas J Vogl
There is recent interest in the use of dual-energy computed tomography (CT) in head and neck imaging, and the results are encouraging. This article reviews dual-energy CT applications as complementary tools to conventional CT scanning in the evaluation of cervical lymphadenopathy. The article cites the most relevant studies and highlights their results. Single-source and dual-source dual-energy applications including virtual noncontrast images, linear and nonlinear image blending, monochromatic images, iodine quantification, and spectral Hounsfield unit attenuation curve analysis are reviewed...
August 2017: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/28711199/dual-energy-computed-tomography-physical-principles-approaches-to-scanning-usage-and-implementation-part-1
#15
REVIEW
Reza Forghani, Bruno De Man, Rajiv Gupta
There are increasing applications of dual-energy computed tomography (CT), a type of spectral CT, in neuroradiology and head and neck imaging. In this 2-part review, the fundamental principles underlying spectral CT scanning and the major considerations in implementing this type of scanning in clinical practice are reviewed. In the first part of this 2-part review, the physical principles underlying spectral CT scanning are reviewed, followed by an overview of the different approaches for spectral CT scanning, including a discussion of the strengths and challenges encountered with each approach...
August 2017: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/28708465/synthesis-characterization-redox-behavior-dna-and-protein-binding-and-antibacterial-activity-studies-of-ruthenium-ii-complexes-of-bidentate-schiff-bases
#16
Hena Paul, Buddhadeb Sen, Tapan Kumar Mondal, Pabitra Chattopadhyay
Two new ruthenium(II) complexes of Schiff base ligands (L) derived from cinnamaldehyde and ethylenediamine formulated as [Ru(L)(bpy)2](ClO4)2, where L(1) = N,N'-bis(4-nitrocinnamald-ehyde)ethylenediamine and L(2) = N,N'-bis(2-nitrocinnamaldehyde)-ethylenediamine for complex 1 and 2, respectively, were isolated in pure form. The complexes were characterized by physicochemical and spectroscopic methods. The electrochemical behavior of the complexes showed the Ru(III)/Ru(II) couple at different potentials with quasi-reversible voltammograms...
July 14, 2017: Nucleosides, Nucleotides & Nucleic Acids
https://www.readbyqxmd.com/read/28703886/dual-energy-ct-a-possible-new-method-to-assess-regression-of-rectal-cancers-after-neoadjuvant-treatment
#17
Issam Al-Najami, Henrik C Drue, Robert Steele, Gunnar Baatrup
BACKGROUND AND OBJECTIVES: The measurement of tumor regression after neoadjuvant oncological treatment has gained increasing interest because it has a prognostic value and because it may influence the method of treatment in rectal cancer. The assessment of tumor regression remains difficult and inaccurate with existing methods. Dual Energy Computed Tomography (DECT) enables qualitative tissue differentiation by simultaneous scanning with different levels of energy. We aimed to assess the feasibility of DECT in quantifying tumor response to neoadjuvant therapy in loco-advanced rectal cancer...
July 13, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28687219/diabetic-macular-edema-with-and-without-subfoveal-neuroretinal-detachment-two-different-morphologic-and-functional-entities
#18
Stela Vujosevic, Tommaso Torresin, Marianna Berton, Silvia Bini, Enrica Convento, Edoardo Midena
PURPOSE: To assess specific morphologic and functional characteristics in eyes with diabetic macular edema (DME) with subfoveal neuroretinal detachment (SND+) vs DME without SND (SND-). DESIGN: Cross-sectional, prospective, comparative case series. METHODS: Seventy-two patients (72 eyes: 22 eyes SND+ and 50 eyes SND-) with treatment-naïve, center-involving DME were evaluated. Data gathering included fundus color photographs, fluorescein angiography, spectral-domain optical coherence tomography (SD-OCT), best-corrected visual acuity (BCVA), and microperimetry...
July 4, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28686423/nanoparticle-uptake-in-plants-gold-nanomaterial-localized-in-roots-of-arabidopsis-thaliana-by-x-ray-computed-nanotomography-and-hyperspectral-imaging
#19
Astrid Avellan, Fabienne Schwab, Armand Masion, Perrine Chaurand, Daniel Borschneck, Vladimir Vidal, Jérôme Rose, Catherine Santaella, Clément Levard
Terrestrial plants can internalize and translocate nanoparticles (NPs). However, direct evidence for the processes driving the NP uptake and distribution in plants is scarce at the cellular level. Here, NP-root interactions were investigated after 10 days of exposure of Arabidopsis thaliana to 10 mg·L(-1) of negatively or positively charged gold NPs (∼12 nm) in gels. Two complementary imaging tools were used: X-ray computed nanotomography (nano-CT) and enhanced dark-field microscopy combined with hyperspectral imaging (DF-HSI)...
July 20, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28684998/bioactive-m-ii-complexes-of-amino-acid-based-n3o-donor-mixed-ligand-in-vitro-and-in-silico-dna-binding-studies
#20
T Daniel Prakash, V Violet Dhayabaran
Three novel mixed ligand M(II) complexes, namely [CoL(1)L(2)Cl2] (1), [CuL(1)L(2)Cl2] (2), and [ZnL(1)L(2)Cl2] (3), were synthesized using 1,4-naphthoquinone, L-histidine, and 1,10-phenanthroline as ligands. The ligand framework and the corresponding structural changes on complexation were ascertained based on the results of elemental analysis, conductivity measurements, magnetic behavior, FT-IR, UV-visible, (1)H NMR, (13)C NMR, ESR spectral studies, and ESI mass spectrometry. The biological action of the ligand (L) and complexes 1-3 such as DNA binding and cleaving ability were studied...
July 2017: Journal of Chemical Biology
keyword
keyword
18194
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"