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https://www.readbyqxmd.com/read/29332130/cerebrospinal-fluid-pressure-revisiting-factors-influencing-optic-nerve-head-biomechanics
#1
Yi Hua, Andrew P Voorhees, Ian A Sigal
Purpose: To model the sensitivity of the optic nerve head (ONH) biomechanical environment to acute variations in IOP, cerebrospinal fluid pressure (CSFP), and central retinal artery blood pressure (BP). Methods: We extended a previously published numerical model of the ONH to include 24 factors representing tissue anatomy and mechanical properties, all three pressures, and constraints on the optic nerve (CON). A total of 8340 models were studied to predict factor influences on 98 responses in a two-step process: a fractional factorial screening analysis to identify the 16 most influential factors, followed by a response surface methodology to predict factor effects in detail...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29331570/meningeal-marginal-zone-b-cell-lymphoma-the-meningioma-trap
#2
Alexandre Villeneuve, François Rubin, Pierre Bonfils
OBJECTIVE: To report a case of marginal zone MALT lymphoma of the temporal dura mater, initially mistaken for temporal meningioma. CASE REPORT: A 60-year-old immunocompetent woman, followed for more than 10 years for temporal meningioma causing vertigo and mixed hearing loss, presented with cervical lymphadenopathy, revealing marked progression of an intracranial lesion, leading to a diagnosis of marginal zone MALT lymphoma based on histological examination of a cervical lymph node...
January 10, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29330432/developing-genome-wide-snps-and-constructing-an-ultrahigh-density-linkage-map-in-oil-palm
#3
Bin Bai, Le Wang, Ying Jun Zhang, May Lee, Rahmadsyah Rahmadsyah, Yuzer Alfiko, Bao Qing Ye, Sigit Purwantomo, Antonius Suwanto, Nam-Hai Chua, Gen Hua Yue
Oil palm (Elaeis guineensis Jacq.) is the leading oil-producing crops and the most important edible oil resource worldwide. DNA markers and genetic linkage maps are essential resources for marker-assisted selection to accelerate genetic improvement. We conducted RAD-seq on an Illumina NextSeq500 to discover genome-wide SNPs, and used the SNPs to construct a linkage map for an oil palm (Tenera) population derived from a cross between a Deli Dura and an AVROS Pisifera. The RAD-seq produced 1,076 million single-end reads across the breeding population containing 155 trees...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29325937/histopathological-analysis-of-tamoxifen-on-epidural-fibrosis
#4
Yasar Ozturk, Ismail Bozkurt, Mesut Emre Yaman, Yahya Guvenc, Tolga Tolunay, Deniz Billur, Fatma Kubra Erbay, Salim Senturk, Gokhan Bozkurt
BACKGROUND: Epidural fibrosis is a challenging topic in spinal surgery. This phenomenon constitutes one of the the main reasons behind "post-laminectomy syndrome" or "failed-back surgery syndrome", which leads to persistent back and leg pain in association with compression and/or stretching the nerve root or the dura. The exact mechanism of action in epidural fibrosis is complex and remains uncertain. Excessive deposition of collagen, fibronectin, and dermatan sulfate known as "extracellular matrix", and decrease of tissue cellularity results in epidural fibrosis...
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29318369/the-incidence-of-biopsy-proven-transformation-in-follicular-lymphoma-in-the-rituximab-era-a-retrospective-analysis-from-the-czech-lymphoma-study-group-clsg-database
#5
Andrea Janikova, Zbynek Bortlicek, Vit Campr, Natasa Kopalova, Katerina Benesova, Michaela Hamouzova, David Belada, Vit Prochazka, Robert Pytlik, Samuel Vokurka, Jan Pirnos, Juraj Duras, Heidi Mocikova, Jiri Mayer, Marek Trneny
The aim of this study is to assess the incidence, risk factors, and outcome of biopsy-proven transformation in follicular lymphoma (FL) patients in the rituximab era. Transformation was analyzed in 1233 patients with initially diagnosed FL grades 1-3A, identified between 2002 and 2012 in the prospectively maintained Czech Lymphoma Study Group database. Only patients with histologically proven transformation (HT) were included. HT occurred in 58 cases at a median of 3.0 years from the initial FL diagnosis; the HT rate was 4% at 5 years...
January 9, 2018: Annals of Hematology
https://www.readbyqxmd.com/read/29317063/trigeminal-long-term-potentiation-as-a-cellular-substrate-for-migraine
#6
Dong-Ho Youn
Most previous studies suggest that the subnucleus caudalis (Vc) of spinal trigeminal nucleus (Vsp) plays a key role in the generation and maintenance of migraine, a type of primary headache, by participating in the trigeminovascular system. Furthermore, the excitability of the Vc with the stimulation of the peripheral nociceptive fibers innervating the intracranial vessels or dura matter is regarded as a main cellular substrate for migraine. Here, a revised hypothesis is introduced, reinforcing the previous hypothesis and complementing it...
January 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29315183/middle-fossa-approach-for-cochlear-implantation
#7
Wojciech Gawęcki, Michał Karlik, Łukasz Borucki, Maciej Wróbel, Olgierd Maciej Stieler, Witold Szyfter
OBJECTIVE: To present qualification criteria, surgery, and results of cochlear implantation via the middle fossa approach. STUDY DESIGN: A retrospective analysis of medical charts of patients. SETTING: Cochlear implant program in academic medical center. PATIENTS: Six adults after middle ear surgery due to chronic otitis media with bilateral deafness or profound hearing loss. INTERVENTION: Analysis aimed to identify patients qualified for cochlear implantation via middle fossa approach and to present surgery and result...
February 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29313554/a-better-method-for-repairing-lumbar-dural-tears-a-review-of-the-literature
#8
Evan Mullen, John Caridi, Jeremy R Steinberge, Raj Shrivastava
Although dural tears are a frequent complication of lumbar spine surgery, no standardized method exists for their treatment. Given the growing number of spinal procedures performed worldwide, it is important to codify an effective strategy for managing repair of the dura mater. This paper is a review of the comparative effectiveness of the current treatments available for dural tears. Our findings suggest that, where possible, repair should be made via direct suturing using material that minimizes the difference between the size of needle and thread...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29310888/secondary-hyperparathyroidism-causing-increased-jaw-bone-density-and-mandibular-pain-a-case-report
#9
Thomas Aerden, Koenraad Grisar, Margaux Nys, Constantinus Politis
We present the case of a 32-year-old male patient complaining of recurrent mandibular pain for 3.5 years. Panoramic radiography indicated increased cortical density of the mandibular lower border. Scintigraphy and single-photon emission computed tomography revealed metabolic hyperactivity in that region without pathologic lymph nodes. A bone biopsy specimen of the mandibular lower border did not have inflammation or cytologic atypia. Endocrinologic investigation confirmed secondary hyperparathyroidism as a result of hypovitaminosis D...
December 7, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29310723/iatrogenic-creutzfeldt-jakob-disease-with-amyloid-%C3%AE-pathology-an-international-study
#10
Ignazio Cali, Mark L Cohen, Stéphane Haїk, Piero Parchi, Giorgio Giaccone, Steven J Collins, Diane Kofskey, Han Wang, Catriona A McLean, Jean-Philippe Brandel, Nicolas Privat, Véronique Sazdovitch, Charles Duyckaerts, Tetsuyuki Kitamoto, Ermias D Belay, Ryan A Maddox, Fabrizio Tagliavini, Maurizio Pocchiari, Ellen Leschek, Brian S Appleby, Jiri G Safar, Lawrence B Schonberger, Pierluigi Gambetti
The presence of pathology related to the deposition of amyloid-β (Aβ) has been recently reported in iatrogenic Creutzfeldt-Jakob disease (iCJD) acquired from inoculation of growth hormone (GH) extracted from human cadaveric pituitary gland or use of cadaveric dura mater (DM) grafts.To investigate this phenomenon further, a cohort of 27 iCJD cases - 21 with adequate number of histopathological sections - originating from Australia, France, Italy, and the Unites States, were examined by immunohistochemistry, amyloid staining, and Western blot analysis of the scrapie prion protein (PrPSc), and compared with age-group matched cases of sporadic CJD (sCJD), Alzheimer disease (AD) or free of neurodegenerative diseases (non-ND)...
January 8, 2018: Acta Neuropathologica Communications
https://www.readbyqxmd.com/read/29308555/a-technique-for-in-vitro-studying-of-the-permeability-of-the-spinal-cord-dura-mater
#11
V V Krasnov, M V Stogov, T A Silant'eva, N V Kubrak, E A Kireeva
We propose an in vitro method for studying permeability of spinal cord dura mater for components of autological serum using an original device. Sixty native samples of the spinal cord dura mater obtained from 12 mongrel dogs were used for testing of the device. The coefficient of permeability variation (V) for blood serum substances did not exceed 5% in most cases excluding lactate (V=8.03%). Analysis of spinal cord dura mater permeability in vitro for various substances using the developed device provides reproducible results with acceptable variability (5-10%)...
January 8, 2018: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29307354/intracranial-dural-calvarial-and-skull-base-metastases
#12
Rebecca A Harrison, Joo Yeon Nam, Shiao-Pei Weathers, Franco DeMonte
Metastatic disease to the intracranial dura, the calvarium, and the skull base is relatively uncommon but presents unique diagnostic and management challenges in the patient with cancer. Modern imaging techniques have facilitated the detection of intracranial tumor deposits, leading to increased incidence. While dural and calvarial metastases often present with nonspecific symptoms, skull base metastases present with distinct clinical syndromes dependent on the local neurovascular structures affected. Intracranial dural metastases can often be confused with meningioma and pose a diagnostic challenge, as well as significant neurologic morbidity, especially in the setting of hemorrhage...
2018: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/29300964/piezosurgery-a-safe-technique-to-perform-lateral-suboccipital-craniotomy
#13
Juergen Grauvogel, Waseem Masalha, Dieter Henrik Heiland, Nadja Jarc, Tanja Daniela Grauvogel, Christian Scheiwe
BACKGROUND: Piezosurgery (PS) is a relatively new technique based on microvibrations generated by the piezoelectric effect. It selectively cuts bone tissue and preserves the surrounding soft tissue. OBJECTIVE: To evaluate the use of PS for performing lateral suboccipital craniotomy. METHODS: PS was used to perform a lateral suboccipital craniotomy in 22 patients who underwent surgery for different cerebellopontine angle (CPA) pathologies in the neurosurgical department...
December 29, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29299907/self-assembled-layering-of-magnetic-nanoparticles-in-a-ferrofluid-at-silicon-surfaces
#14
Katharina Theis-Broehl, Erika C Vreeland, Andrew Gomez, Dale L Huber, Apurve Saini, Max Wolff, Brian Maranville, Erik Brok, Kathryn L Krycka, Joseph A Dura, Julie A Borchers
This article describes the 3D self-assembly of monodisperse colloidal magnetite nanoparticles from a dilute water-based ferrouid onto a silicon surface and the dependence of the resultant magnetic structure with applied field. The nanoparticles assemble into close-packed layers at the surface followed by more loosely-packed ones. The magnetic field-dependent magnetization of the individual nanoparticle layers depends on both the rotational freedom of the layer and the magnetization of the adjacent layers. For layers in which the nanoparticles are more free to rotate, the easy axis of the nanoparticle can readily orient along the field direction...
January 4, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29288843/collin-s-maccarty-1915-2003-inventor-of-the-maccarty-keyhole-as-the-starting-burr-hole-for-orbitozygomatic-craniotomy
#15
REVIEW
Fareed Jumah, Nimer Adeeb, Rimal Hanif Dossani
INTRODUCTION: Dr. Collin S. MacCarty (1915-2003) invented the MacCarty keyhole, which is now widely used as the starting burr hole for orbitozygomatic craniotomy. We present a historical vignette on MacCarty's life and chronicle his contributions to neurosurgery. METHODS: A detailed search for articles relating to the biography and professional career of Dr. MacCarty was conducted on PubMed and Google Scholar using the keywords "Collin MacCarty" and "MacCarty keyhole"...
December 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29286326/role-of-rdw-in-prediction-of-burn-after-caustic-substance-ingestion
#16
Emrah Aydin, Omer Faruk Beser, Soner Sazak, Ensar Duras
A quantifiable, quick, inexpensive and reproducible predictor is needed to decide if caustic substance ingestion results in burn regardless of the symptoms. A multicenter cohort study was conducted to investigate the predictive value of red cell distribution width (RDW) in detecting the esophageal burns. The data of 174 patients were retrospectively analyzed. Eleven patients were excluded due to inability to define the substance ingested. Complete blood count (CBC) was taken at admission, and an esophagogastroduodenoscopy was performed within the first 12-24 h in all patients, regardless of their symptoms...
December 29, 2017: Children
https://www.readbyqxmd.com/read/29285681/outcomes-of-ileal-pouch-anal-anastomosis-without-primary-diverting-loop-ileostomy-if-postoperative-sepsis-develops
#17
O A Lavryk, T L Hull, L C Duraes, L Stocchi, J H Ashburn, D Liska, E Gorgun, H Kessler
BACKGROUND: The aim of the present study was to assess the short-term and long-term consequences of diverting loop ileostomy (DLI) omission in ileal pouch-anal anastomosis (IPAA) surgery complicated by postoperative pelvic sepsis. METHODS: This was a retrospective review of a prospectively maintained database. Of 4031 patients who underwent IPAA in 1983-2014, 357 developed IPAA-related pelvic sepsis with or without anastomotic dehiscence. Patients with Crohn's disease or cancer were excluded...
December 28, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29285586/intracranial-ewing-sarcoma-four-pediatric-examples
#18
Michael J Yang, Ros Whelan, Jennifer Madden, Jean M Mulcahy Levy, B K Kleinschmidt-DeMasters, Todd C Hankinson, Nicholas K Foreman, Michael H Handler
BACKGROUND: Ewing sarcoma typically arises in bone and is unrelated to intraparenchymal small blue cell embryonal central nervous system (CNS) tumors previously designated primitive neuroectodermal tumors (PNETs). When the CNS is impacted, it is usually secondary to local extension from either the epidural space, skull, or intracranial or spinal metastases. Primary examples within the cranial vault are rare, usually dural-based, and are largely case reports in the literature. We detail four pediatric patients with solitary, primary intracranial Ewing sarcoma, all manifesting the archetypal EWRS1 gene rearrangement that confirms diagnosis...
December 28, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29285355/glioblastoma-fed-by-middle-meningeal-artery-and-displaying-cyst-formation-soon-after-repeated-implantation-of-carmustine-wafers-a-case-report
#19
Shun Yamamuro, Yuya Hanashima, Sodai Yoshimura, Hiroyuki Aoki, Koki Kamiya, Yusuke Takamine, Hiroshi Negishi, Atsuo Yoshino
The present study reported an unusual case of temporal lobe glioblastoma (GBM) fed from the middle meningeal artery that progressed rapidly. A 66-year-old male was admitted to the Department of Neurosurgery at Nihon University Itabashi Hosipital (Tokyo, Japan) with epilepsy. Magnetic resonance imaging disclosed a small well-enhanced right middle fossa mass lesion, which was relatively boundary-clear and attached to the dura mater. An angiogram showed a stain fed from the right middle meningeal artery. The mass lesion was removed completely by surgery and diagnosed pathologically as GBM...
December 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29284601/clinical-and-radiologic-characteristics-of-deep-lumbosacral-dural-arteriovenous-fistulas
#20
F Jablawi, O Nikoubashman, G A Schubert, M Dafotakis, F-J Hans, M Mull
BACKGROUND AND PURPOSE: Spinal dural arteriovenous fistulas located in the deep lumbosacral region are rare and the most difficult to diagnose among spinal dural arteriovenous fistulas located elsewhere in the spinal dura. Specific clinical and radiologic features of these fistulas are still inadequately reported and are the subject of this study. MATERIALS AND METHODS: We retrospectively evaluated all data of patients with spinal dural arteriovenous fistulas treated and/or diagnosed in our institution between 1990 and 2017...
December 28, 2017: AJNR. American Journal of Neuroradiology
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