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https://www.readbyqxmd.com/read/27906164/early-sigmoidoscopy-or-colonoscopy-is-associated-with-improved-hospital-outcomes-in-ulcerative-colitis-related-hospitalization
#1
Kenneth Obi, Alice Hinton, Lindsay Sobotka, Razvan Arsenescu, Somashekar G Krishna, Edward J Levine, Cheng Zhang
OBJECTIVES: Performing a sigmoidoscopy or colonoscopy is recommended for assessment of disease activity, excluding infection, and guiding medical treatment during ulcerative colitis (UC)-related hospitalizations. However, it is unknown whether the timing of endoscopy impacts clinical outcomes. The objective of our study was to determine the impact of timing of endoscopy on hospital outcomes in patients with UC-related hospitalizations. METHODS: This is a cross-sectional study using data from the Nationwide Inpatient Sample database (2006-2013)...
December 1, 2016: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/27905836/invasive-pneumococcal-disease-from-a-tertiary-care-hospital-in-the-post-vaccine-era
#2
Sevgen Tanır Basaranoglu, Eda Karadag Oncel, Kubra Aykac, Yasemin Ozsurekci, Ali Bulent Cengiz, Ates Kara, Mehmet Ceyhan
A breakthrough infection occurring with 13-valent pneumococcal conjugate vaccine (PCV13) in Turkey are previously described. A breakthrough infection is defined as IPD in a child who had received ≥1 PCV-7 or PCV-13 and for which the pneumococcal isolate was a vaccine serotype. During one year period, among six patients with invasive pneumococcal infection, two patients were considered to have a vaccine failure with serotype 19F. Antibiotic resistance results were remarkable; macrolide resistance were observed in all strains except one, and high and intermediate penicillin resistance were determined in two strains...
December 1, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27904861/a-recent-advance-in-image-guided-locoregional-therapy-for-hepatocellular-carcinoma
#3
REVIEW
Yaoping Shi, Bo Zhai
BACKGROUND: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third most common cause of cancer-related deaths. Hepatic resection and liver transplantation are considered to be the preferred treatment for HCC. However, as novel therapeutic options such as image-guided locoregional therapies have emerged and been refined, the manner in which HCC is treated has changed dramatically compared with what it was considered just 2 decades earlier. SUMMARY: This study reviews the current results of various image-guided locoregional therapies for treating HCC, especially focusing on thermal ablative and transarterial techniques...
October 2016: Gastrointestinal Tumors
https://www.readbyqxmd.com/read/27898721/hepatitis-b-virus-infections-and-associated-factors-among-pregnant-women-attending-antenatal-care-clinic-at-deder-hospital-eastern-ethiopia
#4
Abdi Umare, Berhanu Seyoum, Tesfaye Gobena, Tamirat Haile Mariyam
BACKGROUND: Hepatitis B virus (HBV) infection is a serious public health problem worldwide. Reports have shown that 68,600 people die of HBV infection and more than 300,000 deaths due to liver cancer secondary to hepatitis B every year globally. Women who are infected with HBV can vertically transmit the infection to their infants. This study aims to determine the prevalence of HBV infection and associated factors among pregnant women. METHODS AND FINDINGS: A hospital-based cross-sectional study was conducted among pregnant women who attended antenatal care clinic (ANC) for routine pregnancy check-up between 18 March 2015 and 15 May 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27896906/identifying-patients-for-safe-early-hospital-discharge-following-st-elevation-myocardial-infarction
#5
Musa A Sharkawi, Andreas Filippaios, Saurabh S Dani, Sachin P Shah, Nabila Riskalla, David M Venesy, Sherif B Labib, Frederic S Resnic
OBJECTIVES: To examine whether the CADILLAC risk score is an effective method of patient stratification for early discharge following ST elevation myocardial infarction (STEMI). BACKGROUND: Patients with STEMI are typically hospitalized to monitor for serious complications such as arrhythmias, heart failure, and reinfarction. Optimal length of stay is unclear. Whether low risk patients can be safely discharged before 72 hr of hospitalization is unclear. METHODS: Patients with STEMI who underwent successful PCI were retrospectively stratified using CADILLAC risk score to low risk (n = 123) and intermediate to high risk (n = 105)...
November 29, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27896896/presumed-tuberculous-uveitis-in-non-endemic-country-for-tuberculosis-case-series-from-a-new-zealand-tertiary-uveitis-clinic
#6
Ken K Ng, Mitzi Nisbet, Erika M Damato, Joanne L Sims
BACKGROUND: To describe the clinical spectrum of presumed tuberculous (TB) uveitis in a developed, non-endemic country of high immigrant population. DESIGN: Retrospective review of a consecutive case series. PARTICIPANTS: All 39 patients diagnosed with presumed TB uveitis at the tertiary uveitis service in Auckland from 2007 to 2014. METHODS: Clinical chart review. MAIN OUTCOME MEASURES: Patient demographics, risk factors, ophthalmic manifestations, management and outcome...
November 28, 2016: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27895040/the-role-of-non-invasive-cardiovascular-imaging-in-the-assessment-of-cardiovascular-risk-in-rheumatoid-arthritis-where-we-are-and-where-we-need-to-be
#7
REVIEW
Graham J Fent, John P Greenwood, Sven Plein, Maya H Buch
This review assesses the risk assessment of cardiovascular disease (CVD) in rheumatoid arthritis (RA) and how non-invasive imaging modalities may improve risk stratification in future. RA is common and patients are at greater risk of CVD than the general population. Cardiovascular (CV) risk stratification is recommended in European guidelines for patients at high and very high CV risk in order to commence preventative therapy. Ideally, such an assessment should be carried out immediately after diagnosis and as part of ongoing long-term patient care in order to improve patient outcomes...
November 28, 2016: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/27894709/external-validation-in-an-intermediate-unit-of-a-respiratory-decompensation-model-trained-in-an-intensive-care-unit
#8
Holly N Blackburn, Matthew T Clark, Travis J Moss, Jeffrey S Young, J Randall Moorman, Douglas E Lake, J Forrest Calland
BACKGROUND: Preventing urgent intubation and upgrade in level of care in patients with subclinical deterioration could be of great utility in hospitalized patients. Early detection should result in decreased mortality, duration of stay, and/or resource use. The goal of this study was to externally validate a previously developed, vital sign-based, intensive care unit, respiratory instability model on a separate population, intermediate care patients. METHODS: From May 2014 to May 2016, the model calculated relative risk of adverse events every 15 minutes (n = 373,271 observations) for 2,050 patients in a surgical intermediate care unit...
November 25, 2016: Surgery
https://www.readbyqxmd.com/read/27894356/transmission-of-calicophoron-daubneyi-and-fasciola-hepatica-in-galicia-spain-temporal-follow-up-in-the-intermediate-and-definitive-hosts
#9
Javier Iglesias-Piñeiro, Marta González-Warleta, José Antonio Castro-Hermida, María Córdoba, Camino González-Lanza, Yolanda Manga-González, Mercedes Mezo
BACKGROUND: Paramphistomosis caused by Calicophoron daubneyi and fasciolosis caused by Fasciola hepatica are common parasitic diseases of livestock animals. Transmission of the diseases depends on the presence of intermediate hosts, i.e. freshwater gastropods such as lymnaeids. We carried out a 2-year-long study of the dynamics of the snail population acting as the intermediate host for these parasites, considering the population structure in terms of size/age and infection status. In addition, we determined the kinetics of trematode egg excretion in grazing cows...
November 29, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27890494/neuroendocrine-tumors-of-the-lung-current-challenges-and-advances-in-the-diagnosis-and-management-of-well-differentiated-disease
#10
REVIEW
Andrew E Hendifar, Alberto M Marchevsky, Richard Tuli
Neuroendocrine tumors (NET) comprise a heterogeneous group of malignancies that arise from neuroendocrine cells throughout the body, most commonly originating from the lungs and gastrointestinal tract. Lung NET can be classified as well-differentiated (low-grade typical carcinoids [TC] and intermediate-grade atypical carcinoids [AC]) and poorly differentiated (high-grade large cell neuroendocrine carcinoma or small cell lung carcinoma). The incidence of these tumors is increasing, but disease awareness remains low among thoracic specialists who are often involved in the diagnosis and early treatment for these patients...
November 23, 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27889552/relation-of-red-blood-cell-distribution-width-with-chads2-and-cha2ds2-vasc-score-in-chinese-patients-with-non-valvular-atrial-fibrillation
#11
Tong Liu, Qingmiao Shao, Panagiotis Korantzopoulos, Shuai Miao, Zhiwei Zhang, Gang Xu, Ruyu Yuan, Guangping Li
BACKGROUND: Higher red cell distribution width (RDW) predicts adverse events in patients with cardiovascular diseases. However, there are limited data regarding the relationship between RDW and thromboembolism risk in the patients with atrial fibrillation (AF). We aimed to investigate the association between RDW and CHADS2, CHA2DS2-VASc scores used for the evaluation of thromboembolic risk in patients with non-valvular atrial fibrillation (AF). METHODS: Our study included 99 patients with AF (68 paroxysmal AF; 31 persistent AF)...
November 14, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27881250/opportunistic-risk-screening-for-type-2-diabetes-exploring-of-application-of-diabetes-risk-assessment-tool-in-community-pharmacy-in-australia-and-thailand
#12
Thitaporn Thoopputra, Tipaporn Pongmesa, David Andrew Newby, Jennifer Schneider, Shu Chuen Li
OBJECTIVE: To evaluate the feasibility of providing diabetes risk assessment at community pharmacy level in Australia and Thailand from organizational aspects. METHODS: The intervention study was conducted in eight community pharmacies in New South Wales, Australia, and six community pharmacies in Central Thailand. Diabetes risk assessment tools were applied to determine the risk of developing type 2 diabetes. An open-ended question was asked to solicit the willingness-to-pay value for the service...
May 2016: Value in Health Regional Issues
https://www.readbyqxmd.com/read/27881246/referral-for-kidney-transplantation-and-indicators-of-quality-of%C3%A2-dialysis-care-a-cross-sectional-study
#13
Laura C Plantinga, Stephen O Pastan, Adam S Wilk, Jenna Krisher, Laura Mulloy, Eric M Gibney, Rachel E Patzer
BACKGROUND: Dialysis facility performance measures to improve access to kidney transplantation are being considered. Referral of patients for kidney transplantation evaluation by the dialysis facility is one potential indicator, but limited data exist to evaluate whether referral is associated with existing dialysis facility quality indicators. STUDY DESIGN: Cross-sectional study. SETTING & PARTICIPANTS: 12,926 incident (July 2005 to September 2011) adult (aged 18-69 years) patients treated at 241 dialysis facilities with complete quality indicator information from US national registry data linked to transplantation referral data from all 3 Georgia kidney transplantation centers...
November 20, 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/27879283/infant-videofluoroscopic-swallow-study-testing-swallowing-interventions-and-future-acute-respiratory-illness
#14
Eric R Coon, Rajendu Srivastava, Gregory J Stoddard, Sheena Reilly, Christopher G Maloney, Susan L Bratton
OBJECTIVES: Tube feedings are commonly prescribed to infants with swallowing abnormalities detected by videofluoroscopic swallow study (VFSS), but there are no studies demonstrating efficacy of these interventions to reduce risk of acute respiratory illness (ARI). We sought to measure the association between swallowing interventions and future ARI, among VFSS-tested infants. METHODS: Retrospective cohort of all infants (<12 months) tested with VFSS at a children's hospital between January 1, 2010, and January 1, 2012...
November 22, 2016: Hospital Pediatrics
https://www.readbyqxmd.com/read/27878044/a-comparative-study-of-radical-prostatectomy-and-permanent-seed-brachytherapy-for-low-and-intermediate-risk-prostate-cancer
#15
Daniel Taussky, Véronique Ouellet, Guila Delouya, Fred Saad
INTRODUCTION: We sought to compare the outcomes between radical prostatectomy (RP) and permanent seed prostate brachytherapy (PB) in patients with low- and low-intermediate-risk prostate cancer from a single tertiary care centre. METHODS: Patients were selected from our institute's internal database based on preoperative selection criteria from the National Comprehensive Cancer Network (NCCN) guidelines (2015) for low- and intermediate-risk patients. No patient had received any neo-adjuvant androgen-deprivation therapy...
August 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27877906/structural-behavior-of-laser-irradiated-%C3%AE-fe2o3-nanocrystals-dispersed-in-porous-silica-matrix-%C3%AE-fe2o3-to-%C3%AE-fe2o3-phase-transition-and-formation-of-%C3%AE%C2%B5-fe2o3
#16
Yassine El Mendili, Jean-François Bardeau, Nirina Randrianantoandro, Jean-Marc Greneche, Fabien Grasset
The effects of laser irradiation on γ-Fe2O3 4 ± 1 nm diameter maghemite nanocrystals synthesized by co-precipitation and dispersed into an amorphous silica matrix by sol-gel methods have been investigated as function of iron oxide mass fraction. The structural properties of γ-Fe2O3 phase were carefully examined by X-ray diffraction and transmission electron microscopy. It has been shown that γ-Fe2O3 nanocrystals are isolated from each other and uniformly dispersed in silica matrix. The phase stability of maghemite nanocrystals was examined in situ under laser irradiation by Raman spectroscopy and compared with that resulting from heat treatment by X-ray diffraction...
2016: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/27871283/improving-the-quality-of-primary-care-by-allocating-performance-based-targets-in-a-diverse-insured-population
#17
Ronit Peled, Avi Porath, Rachel Wilf-Miron
BACKGROUND: Primary Care Health organizations, operating under universal coverage and a regulated package of benefits, compete mainly over quality of care. Monitoring, primary care clinical performance, has been repeatedly proven effective in improving the quality of care. In 2004, Maccabi Healthcare Services (MHS), the second largest Israeli HMO, launched its Performance Measurement System (PMS) based on clinical quality indicators. A unique module was built in the PMS to adjust for case mix while tailoring targets to the local units...
November 21, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27869889/-anmco-sicp-sigo-consensus-document-pregnancy-and-congenital-heart-disease
#18
Innocenzo Bianca, Giovanna Geraci, Michele Massimo Gulizia, Gabriele Egidy-Assenza, Chiara Barone, Marcello Campisi, Annalisa Alaimo, Rachele Adorisio, Francesca Comoglio, Silvia Favilli, Gabriella Agnoletti, Maria Gabriella Carmina, Massimo Chessa, Berardo Sarubbi, Maurizio Mongiovì, Maria Giovanna Russo, Sebastiano Bianca, Giuseppe Canzone, Marco Bonvicini, Elsa Viora, Marco Poli
The success of cardiac surgery over the past 50 years has increased numbers and median age of survivors with congenital heart disease (CHD). Adults now represent two-thirds of patients with CHD; in the United States alone the number is estimated to exceed 1 million.In this population many affected women reach reproductive age and wish to have children. While in many CHD patients pregnancy can be accomplished successfully, some special situations with complex anatomy, iatrogenic or residual pathology are associated with an increased risk of severe maternal and fetal complications...
September 2016: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/27869887/-anmco-position-paper-hospital-discharge-planning
#19
Mauro Mennuni, Michele Massimo Gulizia, Gianfranco Alunni, Antonio Francesco Amico, Francesco Maria Bovenzi, Roberto Caporale, Furio Colivicchi, Andrea Di Lenarda, Giuseppe Di Tano, Sabrina Egman, Francesco Fattirolli, Domenico Gabrielli, Giovanna Geraci, Giovanni Gregorio, Gian Francesco Mureddu, Federico Nardi, Donatella Radini, Carmine Riccio, Fausto Rigo, Marco Sicuro, Stefano Urbinati, Guerrino Zuin
Hospital discharge is often poorly standardized and is characterized by discontinuity and fragmentation of care, putting patients at high risk of post-discharge adverse events and early readmission. The present ANMCO position paper reviews the modifiable components of the hospital discharge process related to adverse events or rehospitalizations and suggests the optimal methods for redesign the whole discharge process. The key principles for proper hospital discharge or transfer of care acknowledge that hospital discharge:- is not an isolated event, but a process that has to be planned immediately after admission, ensuring that the patient and the caregiver understand and contribute to the planned decisions as equal partners;- is facilitated by a comprehensive systemic approach that begins with a multidimensional evaluation process;- must be organized by an operator who is responsible for the coordination of all phases of the hospital patient pathway, involving afterwards the physician and transferring to them the information and responsibility;- is the result of an integrated multidisciplinary team approach;- uses appropriately the transitional and intermediate care services;- is carried out in an organized system of care and continuum of services;- programs the passage of information to after-discharge services...
September 2016: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/27869480/caregiver-profiles-in-dementia-related-to-quality-of-life-depression-and-perseverance-time-in-the-european-actifcare-study-the-importance-of-social-health
#20
Eveline P C J Janssen, Marjolein de Vugt, Sebastian Köhler, Claire Wolfs, Liselot Kerpershoek, Ron L H Handels, Martin Orrell, Bob Woods, Hannah Jelley, Astrid Stephan, Anja Bieber, Gabriele Meyer, Knut Engedal, Geir Selbaek, Anders Wimo, Kate Irving, Louise Hopper, Maria Marques, Manuel Gonçalves-Pereira, Elisa Portolani, Orazio Zanetti, Frans R Verhey
OBJECTIVES: To identify caregiver profiles of persons with mild to moderate dementia and to investigate differences between identified caregiver profiles, using baseline data of the international prospective cohort study Actifcare. METHODS: A latent class analysis was used to discover different caregiver profiles based on disease related characteristics of 453 persons with dementia and their 453 informal caregivers. These profiles were compared with regard to quality of life (CarerQoL score), depressive symptoms (HADS-D score) and perseverance time...
November 21, 2016: Aging & Mental Health
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