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https://www.readbyqxmd.com/read/28531989/mechanical-behaviour-of-biodegradable-az31-magnesium-alloy-after-long-term-in-vitro-degradation
#1
Isaiah Adekanmbi, Christopher Z Mosher, Helen H Lu, Mathis Riehle, Haytham Kubba, K Elizabeth Tanner
Biodegradable magnesium alloys including AZ31 are exciting candidates for temporary implants as they eliminate the requirement for surgical removal, yet have higher mechanical properties than degradable polymers. However, the very long term mechanical properties and degradation of these alloys have not been fully characterized. The tensile, bending and corrosion behaviour of biodegradable AZ31 Mg alloy specimens have been investigated for up to 9months in vitro in phosphate buffered saline (PBS). Small AZ31 Mg specimens showed a significant drop in bend yield strength and modulus after 3months in vitro degradation and an average mass loss of 6...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28531896/gamma-knife-radiosurgery-for-vestibular-schwannomas-and-quality-of-life-evaluation
#2
Oren Berkowitz, Yueh-Ying Han, Evelyn O Talbott, Aditya K Iyer, Hideyuki Kano, Douglas Kondziolka, Mason A Brown, L Dade Lunsford
BACKGROUND: Further investigation is needed to look at the impact of vestibular schwannoma (VS) on the health-related quality of life (QOL) of participants who undergo Gamma Knife® radiosurgery (GKRS). OBJECTIVES: Investigators compared the QOL for VS participants to reported US population norms in order to evaluate disease burden and long-term QOL several years after GKRS. METHODS: This cross-sectional study surveyed participants to assess hearing status, tinnitus, imbalance, vertigo, as well as the Short-Form 36-item Health Questionnaire (SF-36)...
May 23, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28531824/is-subclinical-gambling-really-subclinical
#3
Jeremiah Weinstock, Laura M April, Selmi Kallmi
Gambling disorder and substance use disorders (SUD) overlap in terms of etiology and diagnostic constructs (e.g., preoccupation, loss of control), yet diagnostic thresholds for the disorders are different. Currently, endorsing 2-3 gambling disorder criteria does not warrant a diagnosis while endorsing 2-3 SUD criteria does. The aim of this study was to examine whether subclinical gamblers (i.e., endorsing 2-3 gambling disorder criteria) experience psychosocial dysfunction equivalent to individuals who are diagnosed with mild severity SUD (i...
May 15, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28531766/development-and-initial-validation-of-a-cessation-fatigue-scale
#4
Amanda R Mathew, Bryan W Heckman, Ellen Meier, Matthew J Carpenter
BACKGROUND: Smoking cessation fatigue, or tiredness of attempting to quit smoking, has been posited as a latent construct encompassing loss of motivation, loss of hope in cessation success, decreased self-efficacy, and exhaustion of self-control resources. Despite the potential clinical impact of characterizing cessation fatigue, there is currently no validated measure to assess it. Using a rational scale development approach, we developed a cessation fatigue measure and examined its reliability and construct validity in relation to a) smokers' experience of a recently failed quit attempt (QA) and b) readiness to engage in a subsequent QA...
May 17, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28531563/what-do-individuals-with-morbid-obesity-report-as-a-usual-dietary-intake-a-narrative-review-of-available-evidence
#5
Cathy M Harbury, Elisabeth E Verbruggen, Robin Callister, Clare E Collins
BACKGROUND: In several developed countries, as obesity prevalence doubles it has quadrupled for morbid obesity (BMI ≥ 40 kgm(-2)). As more individuals with morbid obesity present for weight loss treatment there is a greater need to understand their dietary habits. No reviews were found in the literature, therefore this systematic review aims to identify and describe the existing evidence on the usual dietary intake of individuals with morbid obesity including those from a general population and those seeking treatment such as weight loss surgery...
June 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28531269/change-in-the-rate-of-biological-aging-in-response-to-caloric-restriction-calerie-biobank-analysis
#6
Daniel W Belsky, Kim M Huffman, Carl F Pieper, Idan Shalev, William E Kraus
Biological aging measures have been proposed as proxies for extension of healthy lifespan in trials of geroprotective therapies that aim to slow aging. Several methods to measure biological aging show promise; but it is not known if these methods are sensitive to changes caused by geroprotective therapy. We conducted analysis of two proposed methods to quantify biological aging using data from a recently concluded trial of an established geroprotector, caloric restriction. We obtained data from the National Institute on Aging CALERIE randomized trial through its public-access biobank (https://calerie...
May 22, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28531247/the-health-cost-of-tobacco-use-in-uganda
#7
Nigar Nargis, Kellen Nyamurungi, Sebastian Olakira Baine, Daniel Kadobera
The economic cost of tobacco use is well documented in high-income countries. It has been measured in relatively fewer low-and middle-income countries, and much less in sub-Saharan Africa despite the longstanding recognition of significant current and future health risk to people attributed by tobacco use in this region. This article fills this gap by estimating the economic cost of tobacco use in Uganda, a low-income country in sub-Saharan Africa. This study estimates the economic cost of tobacco use in Uganda using the cost-of-illnesses approach based on data collected from a survey of patients and caregivers in four major service centers in Mulago National Referral Hospital, namely, Uganda Cancer Institute, Uganda Heart Institute, Chest Clinic and Diabetic Clinic, key informant interviews and secondary sources for the year 2014...
May 22, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28531224/defining-the-vaccination-window-for-respiratory-syncytial-virus-rsv-using-age-seroprevalence-data-for-children-in-kilifi-kenya
#8
Joyce U Nyiro, Ivy K Kombe, Charles J Sande, James Kipkoech, Patience K Kiyuka, Clayton O Onyango, Patrick K Munywoki, Timothy M Kinyanjui, D James Nokes
BACKGROUND: Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract disease in early life and a target for vaccine prevention. Data on the age-prevalence of RSV specific antibodies will inform on optimizing vaccine delivery. METHODS: Archived plasma samples were randomly selected within age strata from 960 children less than 145 months of age admitted to Kilifi County Hospital pediatric wards between 2007 and 2010. Samples were tested for antibodies to RSV using crude virus IgG ELISA...
2017: PloS One
https://www.readbyqxmd.com/read/28531131/the-role-of-interleukin-18-oxidative-stress-and-metabolic-syndrome-in-alzheimer-s-disease
#9
REVIEW
Johanna O Ojala, Elina M Sutinen
The role of interleukins (ILs) and oxidative stress (OS) in precipitating neurodegenerative diseases including sporadic Alzheimer's disease (AD), requires further clarification. In addition to neuropathological hallmarks-extracellular neuritic amyloid-β (Aβ) plaques, neurofibrillary tangles (NFT) containing hyperphosphorylated tau and neuronal loss-chronic inflammation, as well as oxidative and excitotoxic damage, are present in the AD brain. The pathological sequelae and the interaction of these events during the course of AD need further investigation...
May 21, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/28530775/a-surgical-approach-to-iatrogenic-vascular-injuries-in-pediatric-cases
#10
Yüksel Beşir, Orhan Gökalp, Börteçin Eygi, Banu Bahriye Lafcı, Gamze Gökalp, Levent Yılık, Hasan İner, Ali Gürbüz
BACKGROUND: Surgical intervention is mandatory in many children who present with vascular trauma or in complicated cases after medical interventions. In this study, surgical interventions applied after vascular injuries in children were analyzed. METHODS: Between January 2002 and December 2012, 17 patients (aged under 18) who were admitted to the emergency room with vascular injuries were retrospectively analyzed. The data was collected through hospital records...
May 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28530676/mutations-in-dzip1l-which-encodes-a-ciliary-transition-zone-protein-cause-autosomal-recessive-polycystic-kidney-disease
#11
Hao Lu, Maria C Rondón Galeano, Elisabeth Ott, Geraldine Kaeslin, P Jaya Kausalya, Carina Kramer, Nadina Ortiz-Brüchle, Nadescha Hilger, Vicki Metzis, Milan Hiersche, Shang Yew Tay, Robert Tunningley, Shubha Vij, Andrew D Courtney, Belinda Whittle, Elke Wühl, Udo Vester, Björn Hartleben, Steffen Neuber, Valeska Frank, Melissa H Little, Daniel Epting, Peter Papathanasiou, Andrew C Perkins, Graham D Wright, Walter Hunziker, Heon Yung Gee, Edgar A Otto, Klaus Zerres, Friedhelm Hildebrandt, Sudipto Roy, Carol Wicking, Carsten Bergmann
Autosomal recessive polycystic kidney disease (ARPKD), usually considered to be a genetically homogeneous disease caused by mutations in PKHD1, has been associated with ciliary dysfunction. Here, we describe mutations in DZIP1L, which encodes DAZ interacting protein 1-like, in patients with ARPKD. We further validated these findings through loss-of-function studies in mice and zebrafish. DZIP1L localizes to centrioles and to the distal ends of basal bodies, and interacts with septin2, a protein implicated in maintenance of the periciliary diffusion barrier at the ciliary transition zone...
May 22, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28530642/rasa1-regulates-the-function-of-lymphatic-vessel-valves-in-mice
#12
Philip E Lapinski, Beth A Lubeck, Di Chen, Abbas Doosti, Scott D Zawieja, Michael J Davis, Philip D King
Capillary malformation-arteriovenous malformation (CM-AVM) is a blood and lymphatic vessel (LV) disorder that is caused by inherited inactivating mutations of the RASA1 gene, which encodes p120 RasGAP (RASA1), a negative regulator of the Ras small GTP-binding protein. How RASA1 mutations lead to the LV leakage defects that occur in CM-AVM is not understood. Here, we report that disruption of the Rasa1 gene in adult mice resulted in loss of LV endothelial cells (LECs) specifically from the leaflets of intraluminal valves in collecting LVs...
May 22, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28530630/-laparoscopic-management-of-ureteroileal-stenosis-long-term-follow-up
#13
Esteban Emiliani, Pavel Gavrilov, Olga Mayordomo, Josep Salvador, Joan Palou, Antonio Rosales, Humberto Villavicencio
OBJECTIVE: To describe the laparoscopic approach for uretero-ileal anastomosis strictures and to analyse our long term series. METHODS: A retrospective review was performed evaluating our series of patients with benign ureteroileal anastomosis strictures treated laparoscopically from 2011 to 2017. Demographics and perioperative data were obtained and analyzed. Complications were described with the Clavien-Dindo classification. The surgical technique was described and a literature review was performed...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28530618/robotic-colposacropexy
#14
Miguel Angel Ruiz-León, Lorena Fernández-Montarroso, Natalia Pérez-Romero, Isabel Galante-Romo, Luis Eduardo Resel-Folkersma, Jesús Moreno-Sierra
OBJECTIVES: To review the role of robot- assisted laparoscopic colposacropexy (RALCS) as a treatment for pelvic organ prolapse (POP) accordingly with the available literature and our own experience. METHODS: We have analyzed the studies with the results of robot-assisted colposacropexy (RALCS) and others in which this technique is compared with the abdominal (ACS) and/or the laparoscopic approach (LCS), including our own series. The main data collected are surgical time, blood loss, complications, clinical outcomes, quality of life and the different costs of LCS versus RALCS...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28530410/correction-to-kujawa-proudfit-and-klein-2014
#15
(no author information available yet)
Reports an error in "Neural reactivity to rewards and losses in offspring of mothers and fathers with histories of depressive and anxiety disorders" by Autumn Kujawa, Greg Hajcak Proudfit and Daniel N. Klein (Journal of Abnormal Psychology, 2014[May], Vol 123[2], 287-297). In the original article, there was an error in the Measures section. The article stated that the EEG data were band-pass filtered with cutoffs of 0.1 and 30 Hz and baseline corrected using the 200 ms interval prior to feedback. Instead, the data were actually filtered with cutoffs of 0...
May 22, 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/28530292/soil-sorption-of-two-nitramines-derived-from-amine-based-co2-capture
#16
Cathrine Brecke Gundersen, Gijs D Breedveld, Lena Foseid, Rolf D Vogt
Nitramines are potentially carcinogens that form from the amines used in post-combustion CO2 capture (PCCC). The soil sorption characteristics of monoethanol (MEA)- and dimethyl (DMA)-nitramines have been assessed using a batch experimental setup, and defined indirectly by measuring loss of nitramine (LC-MS/MS) from the aqueous phase (0.01 M CaCl2 and 0.1% NaN3) after equilibrium had been established with the soil (24 h). Nitramine soil sorption was found to be strongly dependent on the content of organic matter in the soil (r(2) = 0...
May 22, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28530123/-we-are-a-team-couple-identity-and-memory-loss
#17
Elise Hernandez, Beth Spencer, Berit Ingersoll-Dayton, Alexandra Faber, Allison Ewert
Couplehood can be an important source of resilience in the face of memory loss, but couple identity has only recently been explored and has rarely been measured. This paper examines older spouses' descriptions of their couple identity and discusses salient themes. Data come from 19 couples from the Couples Life Story Project, a life review intervention where one partner has memory loss. Using baseline data, we analyzed how partners depicted their couple identity using a series of separate and overlapping circles...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/28530040/adolescents-with-hiv-and-transition-to-adult-care-in-the-caribbean-central-america-and-south-america-eastern-europe-and-asia-and-pacific-regions
#18
Heather Bailey, Maria Letícia Santos Cruz, Wipaporn Natalie Songtaweesin, Thanyawee Puthanakit
INTRODUCTION: The HIV epidemics in the Caribbean, Central America and South America (CCASA), Eastern Europe (EE) and Asia and Pacific (AP) regions are diverse epidemics affecting different key populations in predominantly middle-income countries. This narrative review describes the populations of HIV-positive youth approaching adolescence and adulthood in CCASA, EE and AP, what is known of their outcomes in paediatric and adult care to date, ongoing research efforts and future research priorities...
May 16, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28530039/transition-from-paediatric-to-adult-care-of-adolescents-living-with-hiv-in-sub-saharan-africa-challenges-youth-friendly-models-and-outcomes
#19
Désiré Lucien Dahourou, Chloé Gautier-Lafaye, Chloe A Teasdale, Lorna Renner, Marcel Yotebieng, Sophie Desmonde, Samuel Ayaya, Mary-Ann Davies, Valériane Leroy
INTRODUCTION: The number of adolescents with perinatally or behaviourally acquired HIV is increasing in low-income countries, and especially in sub-Saharan Africa where HIV prevalence and incidence are the highest. As they survive into adulthood in the era of antiretroviral therapy, there is a pressing need to transfer them from paediatric to adult care, known as the transition of care. We conducted a narrative review of recent evidence on their transition outcomes in Africa, highlighting the specific needs and challenges in these populations and settings, and the different models of care for transition...
May 16, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28530038/hiv-treatment-and-care-services-for-adolescents-a-situational-analysis-of-218-facilities-in-23-sub-saharan-african-countries
#20
Daniella Mark, Alice Armstrong, Catarina Andrade, Martina Penazzato, Luann Hatane, Lina Taing, Toby Runciman, Jane Ferguson
INTRODUCTION: In 2013, an estimated 2.1 million adolescents (age 10-19 years) were living with HIV globally. The extent to which health facilities provide appropriate treatment and care was unknown. To support understanding of service availability in 2014, Paediatric-Adolescent Treatment Africa (PATA), a non-governmental organisation (NGO) supporting a network of health facilities across sub-Saharan Africa, undertook a facility-level situational analysis of adolescent HIV treatment and care services in 23 countries...
May 16, 2017: Journal of the International AIDS Society
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