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https://www.readbyqxmd.com/read/28231286/lexicon-enhanced-sentiment-analysis-framework-using-rule-based-classification-scheme
#1
Muhammad Zubair Asghar, Aurangzeb Khan, Shakeel Ahmad, Maria Qasim, Imran Ali Khan
With the rapid increase in social networks and blogs, the social media services are increasingly being used by online communities to share their views and experiences about a particular product, policy and event. Due to economic importance of these reviews, there is growing trend of writing user reviews to promote a product. Nowadays, users prefer online blogs and review sites to purchase products. Therefore, user reviews are considered as an important source of information in Sentiment Analysis (SA) applications for decision making...
2017: PloS One
https://www.readbyqxmd.com/read/28231064/three-dimensional-ultrasound-for-prenatal-assessment-of-conjoined-twins-additional-advantages
#2
Tuangsit Wataganara, Pornpimol Ruangvutilert, Prasert Sunsaneevithayakul, Kusol Russameecharoen, Katika Nawapun, Nisarat Phithakwatchara
Conjoined twins are a rare, but serious, complication of monozygotic twins. Early prenatal diagnosis of conjoined twins is increasingly made with transvaginal ultrasound and color Doppler studies. Most prenatally diagnosed conjoined twins are terminated due to the high perinatal mortality, but advancement in pediatric surgery has allowed for successful postnatal separation in a small number of cases, and some parents may consider this option over termination of pregnancy. It is important to get a detailed prenatal ultrasound for the site and extent of fusion for an accurate categorization...
February 23, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28230599/a-targeted-next-generation-genetic-sequencing-study-on-tetralogy-of-fallot-combined-with-cleft-lip-and-palate
#3
Lin Liu, Haisong Bu, Yifeng Yang, Zhiping Tan, Fei Zhang, Shijun Hu, Tianli Zhao
BACKGROUND: Congenital heart disease (CHD), plus cleft lip and palate (CLP) are currently the most common types of structural malformation in infants. Many genes have been investigated for their involvement in CHD with CLP. Targeted next-generation sequencing can analyze large amounts of genetic information rapidly, and thus address this question. METHODS: The authors designed a targeted, next-generation sequencing gene panel for 455 genes previously implicated in CHD or CLP...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28230325/serum-phosphatidylinositol-as-a-biomarker-for-bipolar-disorder-liability
#4
Emma Em Knowles, Peter J Meikle, Kevin Huynh, Harald Hh Göring, Rene L Olvera, Samuel R Mathias, Ravi Duggirala, Laura Almasy, John Blangero, Joanne E Curran, David C Glahn
OBJECTIVES: Individuals with bipolar disorder (BPD) exhibit alterations in their phospholipid levels. It is unclear whether these alterations are a secondary consequence of illness state, or if phospholipids and illness risk overlap genetically. If the latter were true, then phospholipids might provide key insights into the pathophysiology of the illness. Therefore, we rank-ordered phospholipid classes by their genetic overlap with BPD risk in order to establish which class might be most informative in terms of increasing our understanding of illness pathophysiology...
February 23, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28230168/phylogenetic-characterizations-of-highly-mutated-ev-b106-recombinants-showing-extensive-genetic-exchanges-with-other-ev-b-in-xinjiang-china
#5
Yang Song, Yong Zhang, Qin Fan, Hui Cui, Dongmei Yan, Shuangli Zhu, Haishu Tang, Qiang Sun, Dongyan Wang, Wenbo Xu
Human enterovirus B106 (EV-B106) is a new member of the enterovirus B species. To date, only three nucleotide sequences of EV-B106 have been published, and only one full-length genome sequence (the Yunnan strain 148/YN/CHN/12) is available in the GenBank database. In this study, we conducted phylogenetic characterisation of four EV-B106 strains isolated in Xinjiang, China. Pairwise comparisons of the nucleotide sequences and the deduced amino acid sequences revealed that the four Xinjiang EV-B106 strains had only 80...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28229563/how-does-social-essentialism-affect-the-development-of-inter-group-relations
#6
Marjorie Rhodes, Sarah-Jane Leslie, Katya Saunders, Yarrow Dunham, Andrei Cimpian
Psychological essentialism is a pervasive conceptual bias to view categories as reflecting something deep, stable, and informative about their members. Scholars from diverse disciplines have long theorized that psychological essentialism has negative ramifications for inter-group relations, yet little previous empirical work has experimentally tested the social implications of essentialist beliefs. Three studies (N = 127, ages 4.5-6) found that experimentally inducing essentialist beliefs about a novel social category led children to share fewer resources with category members, but did not lead to the out-group dislike that defines social prejudice...
February 22, 2017: Developmental Science
https://www.readbyqxmd.com/read/28229502/shared-musical-knowledge-in-11-month-old-infants
#7
Samuel A Mehr, Elizabeth S Spelke
Five-month-old infants selectively attend to novel people who sing melodies originally learned from a parent, but not melodies learned from a musical toy or from an unfamiliar singing adult, suggesting that music conveys social information to infant listeners. Here, we test this interpretation further in older infants with a more direct measure of social preferences. We randomly assigned 64 11-month-old infants to 1-2 weeks' exposure to one of two novel play songs that a parent either sang or produced by activating a recording inside a toy...
February 22, 2017: Developmental Science
https://www.readbyqxmd.com/read/28228927/computational-approaches-for-revealing-the-structure-of-membrane-transporters-case-study-on-bilitranslocase
#8
REVIEW
Katja Venko, A Roy Choudhury, Marjana Novič
The structural and functional details of transmembrane proteins are vastly underexplored, mostly due to experimental difficulties regarding their solubility and stability. Currently, the majority of transmembrane protein structures are still unknown and this present a huge experimental and computational challenge. Nowadays, thanks to X-ray crystallography or NMR spectroscopy over 3000 structures of membrane proteins have been solved, among them only a few hundred unique ones. Due to the vast biological and pharmaceutical interest in the elucidation of the structure and the functional mechanisms of transmembrane proteins, several computational methods have been developed to overcome the experimental gap...
2017: Computational and Structural Biotechnology Journal
https://www.readbyqxmd.com/read/28228667/three-new-species-of-the-killifish-genus-melanorivulus-from-the-central-brazilian-cerrado-savanna-cyprinodontiformes-aplocheilidae
#9
Wilson J E M Costa
Three new species are described from the Neotropical region comprising the Cerrado savannas of the central Brazilian plateaus, which is among the most important biodiversity centres in the world. These species are considered closely related to Melanorivulus dapazi from the same region, with which they share the presence of a rudimentary interarcual cartilage and a dark reddish brown distal margin on the male anal fin. The group comprising Melanorivulus dapazi and the three new species is here named as the Melanorivulus dapazi species group...
2017: ZooKeys
https://www.readbyqxmd.com/read/28228643/a-chemical-probe-toolbox-for-dissecting-the-cancer-epigenome
#10
REVIEW
Jake Shortt, Christopher J Ott, Ricky W Johnstone, James E Bradner
Cancer cell hallmarks are underpinned by transcriptional programmes operating in the context of a dynamic and complicit epigenomic environment. Somatic alterations of chromatin modifiers are among the most prevalent cancer perturbations. There is a pressing need for targeted chemical probes to dissect these complex, interconnected gene regulatory circuits. Validated chemical probes empower mechanistic research while providing the pharmacological proof of concept that is required to translate drug-like derivatives into therapy for cancer patients...
February 23, 2017: Nature Reviews. Cancer
https://www.readbyqxmd.com/read/28228473/violence-related-ambulance-call-outs-in-the-north-west-of-england-a-cross-sectional-analysis-of-nature-extent-and-relationships-to-temporal-celebratory-and-sporting-events
#11
Zara Quigg, Ciara McGee, Karen Hughes, Simon Russell, Mark A Bellis
OBJECTIVE: The aim of this study was to explore the potential of ambulance call-out data in understanding violence to inform about prevention activity. METHOD: This cross-sectional (2013-2015) study examined the nature, extent and characteristics of violence-related ambulance call-outs (n=15 687) across North West England and relationships with temporal, celebratory and sporting events. RESULTS: The majority of call-outs were for men, with a mean age of 33 years...
February 21, 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/28228452/does-the-use-of-a-decision-aid-improve-decision-making-in-prosthetic-heart-valve-selection-a-multicenter-randomized-trial
#12
Nelleke M Korteland, Yunus Ahmed, David R Koolbergen, Marjan Brouwer, Frederiek de Heer, Jolanda Kluin, Eline F Bruggemans, Robert J M Klautz, Anne M Stiggelbout, Jeroen J J Bucx, Jolien W Roos-Hesselink, Peter Polak, Thanasie Markou, Inge van den Broek, Rene Ligthart, Ad J J C Bogers, Johanna J M Takkenberg
BACKGROUND: A Dutch online patient decision aid to support prosthetic heart valve selection was recently developed. A multicenter randomized controlled trial was conducted to assess whether use of the patient decision aid results in optimization of shared decision making in prosthetic heart valve selection. METHODS AND RESULTS: In a 5-center randomized controlled trial, patients were allocated to receive either standard preoperative care (control group) or additional access to the patient decision aid (intervention group)...
February 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28228384/impact-of-disseminated-neuroblastoma-cells-on-the-identification-of-the-relapse-seeding-clone
#13
M Reza Abbasi, Fikret Rifatbegovic, Clemens Brunner, Georg Mann, Andrea Ziegler, Ulrike Pötschger, Roman Crazzolara, Marek Ussowicz, Martin Benesch, Georg Ebetsberger-Dachs, Godfrey Chi-Fung Chan, Neil Jones, Ruth Ladenstein, Inge M Ambros, Peter F Ambros
PURPOSE: Tumor relapse is the most frequent cause of death in stage 4 neuroblastomas. Since genomic information on the relapse precursor cells could guide targeted therapy, our aim was to find the most appropriate tissue for identifying relapse-seeding clones. EXPERIMENTAL DESIGN: We analyzed 10 geographically and temporally separated samples of a single patient by SNP array and validated the data in 154 stage 4 patients. RESULTS: In the case study, aberrations unique to certain tissues and time points were evident besides concordant aberrations shared by all samples...
February 22, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28228131/whole-genome-sequencing-of-one-complex-pedigree-illustrates-challenges-with-genomic-medicine
#14
Han Fang, Yiyang Wu, Hui Yang, Margaret Yoon, Laura T Jiménez-Barrón, David Mittelman, Reid Robison, Kai Wang, Gholson J Lyon
BACKGROUND: Human Phenotype Ontology (HPO) has risen as a useful tool for precision medicine by providing a standardized vocabulary of phenotypic abnormalities to describe presentations of human pathologies; however, there have been relatively few reports combining whole genome sequencing (WGS) and HPO, especially in the context of structural variants. METHODS: We illustrate an integrative analysis of WGS and HPO using an extended pedigree, which involves Prader-Willi Syndrome (PWS), hereditary hemochromatosis (HH), and dysautonomia-like symptoms...
February 23, 2017: BMC Medical Genomics
https://www.readbyqxmd.com/read/28228127/a-review-of-enhanced-paramedic-roles-during-and-after-hospital-handover-of-stroke-myocardial-infarction-and-trauma-patients
#15
Darren Flynn, Richard Francis, Shannon Robalino, Joanne Lally, Helen Snooks, Helen Rodgers, Graham McClelland, Gary A Ford, Christopher Price
BACKGROUND: Ambulance paramedics play a critical role expediting patient access to emergency treatments. Standardised handover communication frameworks have led to improvements in accuracy and speed of information transfer but their impact upon time-critical scenarios is unclear. Patient outcomes might be improved by paramedics staying for a limited time after handover to assist with shared patient care. We aimed to categorize and synthesise data from studies describing development/extension of the ambulance-based paramedic role during and after handover for time-critical conditions (trauma, stroke and myocardial infarction)...
February 23, 2017: BMC Emergency Medicine
https://www.readbyqxmd.com/read/28227916/development-and-pilot-clinical-evaluation-of-a-haptic-based-perception-empathy-biofeedback-device-for-gait-rehabilitation
#16
Kenta Saichi, Kazuhiro Yasuda, Yu Kitaji, Naomi Kaibuki, Hiroyasu Iwata, Kenta Saichi, Kazuhiro Yasuda, Yu Kitaji, Naomi Kaibuki, Hiroyasu Iwata
Recent studies have shown that haptic feedback on the body, either at or away from the desired gait parameter to be changed, can improve gait performance. Here we introduced a haptic-based biofeedback device to supplement the foot pressure information of a paretic foot with a wearable vibrotactile biofeedback device attached to the back. This system provides information regarding a patient's foot pressure pattern to the patient and physical therapist. Therefore, the biofeedback system can share information regarding abnormal gait patterns between patients and therapists...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227823/smartphone-based-swallowing-monitoring-and-feedback-device-for-mealtime-assistance-in-nursing-homes
#17
Naomi Kuramoto, Dushyantha Jayatilake, Kikue Hidaka, Kenji Suzuki, Naomi Kuramoto, Dushyantha Jayatilake, Kikue Hidaka, Kenji Suzuki, Kenji Suzuki, Kikue Hidaka, Dushyantha Jayatilake, Naomi Kuramoto
As many of the elderly are prone to dysphagia, preventing aspirations during mealtime assistance is a huge concern, especially for institutions operated with limited staff. Two of the main course of actions that are taken usually to prevent aspiration are the altering of bolus consistency and altering of the swallowing posture. To assist prevention of pneumonia, we have been developing a smartphone-based wearable technology that can evaluate swallowing ability in real-time. In this paper we will introduce modified version of Swallwoscope adding a posture detection system and a remote swallowing activity visualisation system to our previous work...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227228/multi-view-non-negative-tensor-factorization-as-relation-learning-in-healthcare-data
#18
Hang Wu, May D Wang, Hang Wu, May D Wang, May D Wang, Hang Wu
Discovering patterns in co-occurrences data between objects and groups of concepts is a useful task in many domains, such as healthcare data analysis, information retrieval, and recommender systems. These relational representations come from objects' behaviors in different views, posing a challenging task of integrating information from these views to uncover the shared latent structures. The problem is further complicated by the high dimension of data and the large ratio of missing data. We propose a new paradigm of learning semantic relations using tensor factorization, by jointly factorizing multi-view tensors and searching for a consistent underlying semantic space across each views...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227039/amp-a-platform-for-managing-and-mining-data-in-the-treatment-of-autism-spectrum-disorder
#19
Erik Linstead, Ryan Burns, Duy Nguyen, David Tyler, Erik Linstead, Ryan Burns, Duy Nguyen, David Tyler, Erik Linstead, Duy Nguyen, Ryan Burns, David Tyler
We introduce AMP (Autism Management Platform), an integrated health care information system for capturing, analyzing, and managing data associated with the diagnosis and treatment of Autism Spectrum Disorder in children. AMP's mobile application simplifies the means by which parents, guardians, and clinicians can collect and share multimedia data with one another, facilitating communication and reducing data redundancy, while simplifying retrieval. Additionally, AMP provides an intelligent web interface and analytics platform which allow physicians and specialists to aggregate and mine patient data in real-time, as well as give relevant feedback to automatically learn data filtering preferences over time...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226252/linkage-of-traffic-crash-and-hospitalization-records-with-limited-identifiers-for-enhanced-public-health-surveillance
#20
Sarah Conderino, Lawrence Fung, Slavenka Sedlar, Jennifer M Norton
BACKGROUND: Motor vehicle traffic (MVT) crashes kill or seriously injure approximately 4250 people in New York City (NYC) each year. Traditionally, NYC surveillance practices use hospitalization and crash data separately to monitor trends in MVT-related injuries, but key information linking crash circumstances to health outcomes is lost when analyzing these data sources in isolation. Our objective was to match crash reports to hospitalization records to create a traffic injury surveillance dataset that can be used to describe crash circumstances and related injury outcomes...
February 19, 2017: Accident; Analysis and Prevention
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