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https://www.readbyqxmd.com/read/28444174/catheter-ablation-for-ventricular-tachycardia-in-patients-with-cardiac-sarcoidosis-a-systematic-review
#1
Nikolaos Papageorgiou, Rui Providência, Konstantinos Bronis, Dirk G Dechering, Neil Srinivasan, Lars Eckardt, Pier D Lambiase
Aims: Cardiac sarcoidosis (CS) is associated with a poor prognosis. Important features of CS include heart failure, conduction abnormalities, and ventricular arrhythmias. Ventricular tachycardia (VT) is often refractory to antiarrhythmic drugs (AAD) and immunosuppression. Catheter ablation has emerged as a treatment option for recurrent VT. However, data on the efficacy and outcomes of VT ablation in this context are sparse. Methods and results: A systematic search was performed on PubMed, EMBASE, and Cochrane database (from inception to September 2016) with included studies providing a minimum of information on CS patients undergoing VT ablation: age, gender, VT cycle length, CS diagnosis criteria, and baseline medications...
April 21, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28438841/practice-guideline-summary-sudden-unexpected-death-in-epilepsy-incidence-rates-and-risk-factors-report-of-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american-academy-of-neurology-and-the-american-epilepsy-society
#2
Cynthia Harden, Torbjörn Tomson, David Gloss, Jeffrey Buchhalter, J Helen Cross, Elizabeth Donner, Jacqueline A French, Anthony Gil-Nagel, Dale C Hesdorffer, W Henry Smithson, Mark C Spitz, Thaddeus S Walczak, Josemir W Sander, Philippe Ryvlin
OBJECTIVE: To determine the incidence rates of sudden unexpected death in epilepsy (SUDEP) in different epilepsy populations and address the question of whether risk factors for SUDEP have been identified. METHODS: Systematic review of evidence; modified Grading Recommendations Assessment, Development, and Evaluation process for developing conclusions; recommendations developed by consensus. RESULTS: Findings for incidence rates based on 12 Class I studies include the following: SUDEP risk in children with epilepsy (aged 0-17 years) is 0...
April 25, 2017: Neurology
https://www.readbyqxmd.com/read/28430472/random-number-generation-with-cosmic-photons
#3
Cheng Wu, Bing Bai, Yang Liu, Xiaoming Zhang, Meng Yang, Yuan Cao, Jianfeng Wang, Shaohua Zhang, Hongyan Zhou, Xiheng Shi, Xiongfeng Ma, Ji-Gang Ren, Jun Zhang, Cheng-Zhi Peng, Jingyun Fan, Qiang Zhang, Jian-Wei Pan
Random numbers are indispensable for a variety of applications ranging from testing physics foundations to information encryption. In particular, nonlocality test provide strong evidence for our current understanding of nature-quantum mechanics. All the random number generators (RNGs) used for the existing tests are constructed locally, making the test results vulnerable to the freedom-of-choice loophole. We report an experimental realization of RNGs based on the arrival time of cosmic photons. The measurement outcomes (raw data) pass the standard NIST statistical test suite...
April 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28428184/clinical-and-cost-effectiveness-safety-and-acceptability-of-community-intravenous-antibiotic-service-models-civas-systematic-review
#4
E D Mitchell, C Czoski Murray, D Meads, J Minton, J Wright, M Twiddy
OBJECTIVE: Evaluate evidence of the efficacy, safety, acceptability and cost-effectiveness of outpatient parenteral antimicrobial therapy (OPAT) models. DESIGN: A systematic review. DATA SOURCES: MEDLINE, EMBASE, CINAHL, Cochrane Library, National Health Service (NHS) Economic Evaluation Database (EED), Research Papers in Economics (RePEc), Tufts Cost-Effectiveness Analysis (CEA) Registry, Health Business Elite, Health Information Management Consortium (HMIC), Web of Science Proceedings, International Pharmaceutical Abstracts, British Society for Antimicrobial Chemotherapy website...
April 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28402199/from-menarche-to-menopause-understanding-multigenerational-reproductive-health-milestones
#5
Kimberly Field-Springer, Deleasa Randall-Griffiths, Carol Reece
Our study aims at understanding multigenerational communication among grandmothers, mothers, and daughters experiencing reproductive health transitions from menarche to menopause. Thirty women, 10 triads of grandmothers, mothers, and daughters, participated in narrative interviews to recount their menarche and menopause experiences. Analysis was read using a multilayered approach to interpret discourse positioned from self, reflexive others, and those stories informed by societal meanings. Four dialectical themes informed by generational discursive shifts in talk included (1) covert versus overt talk, (2) recollection of versus indifference to menarche, (3) bound to versus freedom from menstruation, and (4) controlling versus managing bodily changes...
April 12, 2017: Health Communication
https://www.readbyqxmd.com/read/28400075/review-of-general-dental-council-and-general-medical-council-fitness-to-practise-hearings-related-to-maxillofacial-surgery
#6
R Taylor, M H Ali, T E Howe, I Varley
Dually-registered specialists in oral and maxillofacial surgery (OMFS) may be subject to disciplinary hearings by the General Medical Council (GMC) and the General Dental Council (GDC) for the same allegations, a phenomenon referred to as "double jeopardy" within the specialty. Previous efforts by both councils to simplify regulatory arrangements have made little progress. We have therefore reviewed the range and scope of fitness to practise (FTP) proceedings relevant to OMFS. We searched the online GMC register to find registered OMFS specialists and obtained FTP proceedings from 2004-2016 through a Freedom of Information request from the GDC...
April 8, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28390339/perspective-echoes-in-2d-raman-thz-spectroscopy
#7
Peter Hamm, Andrey Shalit
Recently, various spectroscopic techniques have been developed, which can measure the 2D response of the inter-molecular degrees of freedom of liquids in the THz regime. By employing hybrid Raman-THz pulse sequences, the inherent experimental problems of 2D-Raman spectroscopy are circumvented completely, culminating in the recent measurement of the 2D-Raman-THz responses of water and aqueous salt solutions. This review article focuses on the possibility to observe echoes in such experiments, which would directly reveal the inhomogeneity of the typically extremely blurred THz bands of liquids, and hence the heterogeneity of local structures that are transiently formed, in particular, in a hydrogen-bonding liquid such as water...
April 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28389007/single-image-super-resolution-using-self-optimizing-mask-via-fractional-order-gradient-interpolation-and-reconstruction
#8
Qi Yang, Yanzhu Zhang, Tiebiao Zhao, YangQuan Chen
Image super-resolution using self-optimizing mask via fractional-order gradient interpolation and reconstruction aims to recover detailed information from low-resolution images and reconstruct them into high-resolution images. Due to the limited amount of data and information retrieved from low-resolution images, it is difficult to restore clear, artifact-free images, while still preserving enough structure of the image such as the texture. This paper presents a new single image super-resolution method which is based on adaptive fractional-order gradient interpolation and reconstruction...
April 4, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28388251/being-subject-to-restrictions-limitations-and-disciplining-a-thematic-analysis-of-individuals-experiences-in-psychiatric-intensive-care
#9
Martin Salzmann-Erikson, Cecilia Söderqvist
The aim of this study was to describe individuals' experiences of being hospitalized in psychiatric intensive care units (PICUs). Four participants who had previously been admitted in a PICU were interviewed using open-ended questions. The data were analyzed using thematic analysis. Analysis resulted in a synthesis of the various ways patients experienced limitations: (1) Descriptions of Being Limited in the Environment, (2) Descriptions of being Limited in Interactions with Staff, (3) Descriptions of Being Limited in terms of Access to Information, and (4) Descriptions of Having Limited Freedom and Autonomy...
April 7, 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28388132/improved-accuracy-of-hybrid-atomistic-coarse-grained-simulations-using-reparametrised-interactions
#10
Annick Renevey, Sereina Riniker
Reducing the number of degrees of freedom in molecular models-so-called coarse-graining-is a popular approach to increase the accessible time scales and system sizes in molecular dynamics simulations. It involves, however, per se a loss of information. In order to retain a high accuracy in the region of interest, hybrid methods that combine two levels of resolution in a single system are an attractive trade-off. Hybrid atomistic (AT)/coarse-grained (CG) simulations have previously been shown to preserve the secondary structure elements of AT proteins in CG water but to cause an artificial increase in intramolecular hydrogen bonds, resulting in a reduced flexibility of the proteins...
March 28, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28382666/improving-school-experiences-for-adolescents-with-type-1-diabetes
#11
Saori S Kise, Amanda Hopkins, Sandra Burke
BACKGROUND: Diabetes mellitus (diabetes) is one of the most common metabolic diseases in children worldwide and the incidence of type 1 diabetes (T1D) is growing. T1D is complicated to manage and adolescents with diabetes face unique, age-specific challenges. The purpose of this article is to discuss ways in which schools can create a positive environment and improve the experiences and outcomes for adolescents with T1D. METHODS: The Cumulative Index of Nursing and Allied Health Literature (CINAHL) and PubMed databases were searched and yielded a total of 27 articles that were used in this integrative literature review...
May 2017: Journal of School Health
https://www.readbyqxmd.com/read/28379373/genetic-and-phenotypic-heterogeneity-suggest-therapeutic-implications-in-scn2a-related-disorders
#12
Markus Wolff, Katrine M Johannesen, Ulrike B S Hedrich, Silvia Masnada, Guido Rubboli, Elena Gardella, Gaetan Lesca, Dorothée Ville, Mathieu Milh, Laurent Villard, Alexandra Afenjar, Sandra Chantot-Bastaraud, Cyril Mignot, Caroline Lardennois, Caroline Nava, Niklas Schwarz, Marion Gérard, Laurence Perrin, Diane Doummar, Stéphane Auvin, Maria J Miranda, Maja Hempel, Eva Brilstra, Nine Knoers, Nienke Verbeek, Marjan van Kempen, Kees P Braun, Grazia Mancini, Saskia Biskup, Konstanze Hörtnagel, Miriam Döcker, Thomas Bast, Tobias Loddenkemper, Lily Wong-Kisiel, Friedrich M Baumeister, Walid Fazeli, Pasquale Striano, Robertino Dilena, Elena Fontana, Federico Zara, Gerhard Kurlemann, Joerg Klepper, Jess G Thoene, Daniel H Arndt, Nicolas Deconinck, Thomas Schmitt-Mechelke, Oliver Maier, Hiltrud Muhle, Beverly Wical, Claudio Finetti, Reinhard Brückner, Joachim Pietz, Günther Golla, Dinesh Jillella, Karen M Linnet, Perrine Charles, Ute Moog, Eve Õiglane-Shlik, John F Mantovani, Kristen Park, Marie Deprez, Damien Lederer, Sandrine Mary, Emmanuel Scalais, Laila Selim, Rudy Van Coster, Lieven Lagae, Marina Nikanorova, Helle Hjalgrim, G Christoph Korenke, Marina Trivisano, Nicola Specchio, Berten Ceulemans, Thomas Dorn, Katherine L Helbig, Katia Hardies, Hannah Stamberger, Peter de Jonghe, Sarah Weckhuysen, Johannes R Lemke, Ingeborg Krägeloh-Mann, Ingo Helbig, Gerhard Kluger, Holger Lerche, Rikke S Møller
Mutations in SCN2A, a gene encoding the voltage-gated sodium channel Nav1.2, have been associated with a spectrum of epilepsies and neurodevelopmental disorders. Here, we report the phenotypes of 71 patients and review 130 previously reported patients. We found that (i) encephalopathies with infantile/childhood onset epilepsies (≥3 months of age) occur almost as often as those with an early infantile onset (<3 months), and are thus more frequent than previously reported; (ii) distinct phenotypes can be seen within the late onset group, including myoclonic-atonic epilepsy (two patients), Lennox-Gastaut not emerging from West syndrome (two patients), and focal epilepsies with an electrical status epilepticus during slow sleep-like EEG pattern (six patients); and (iii) West syndrome constitutes a common phenotype with a major recurring mutation (p...
March 4, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28378422/derivation-and-initial-validation-of-a-surgical-grading-scale-for-the-preliminary-evaluation-of-adult-patients-with-drug-resistant-focal-epilepsy
#13
Patricia Dugan, Chad Carlson, Nathalie Jetté, Samuel Wiebe, Marjorie Bunch, Ruben Kuzniecky, Jacqueline French
OBJECTIVE: Presently, there is no simple method at initial presentation for identifying a patient's likelihood of progressing to surgery and a favorable outcome. The Epilepsy Surgery Grading Scale (ESGS) is a three-tier empirically derived mathematical scale with five categories: magnetic resonance imaging (MRI), electroencephalography (EEG), concordance (between MRI and EEG), semiology, and IQ designed to stratify patients with drug-resistant focal epilepsy based on their likelihood of proceeding to resective epilepsy surgery and achieving seizure freedom...
April 4, 2017: Epilepsia
https://www.readbyqxmd.com/read/28377650/identifying-dental-anxiety-in-children-s-drawings-and-correlating-it-with-frankl-s-behavior-rating-scale
#14
Jyoti Mathur, Amish Diwanji, Bhumi Sarvaiya, Dipal Sharma
AIM: To develop a simple method to assess the level of anxiety by using children's drawings and correlating them with Frankl's behavior rating scale. MATERIALS AND METHODS: A total of 178 patients aged of 3 to 14 years were handed out two-page forms which contained three sections on coloring and drawing, along with general information, and Frankl's behavior rating scale for the visit. The three types of drawing exercises given to the patients were geometric copy drawings, coloring a nonthreatening figure, and an empty sheet for freehand drawing...
January 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28375008/the-dynameomics-entropy-dictionary-a-large-scale-assessment-of-conformational-entropy-across-protein-fold-space
#15
Clare-Louise Towse, Mikael Akke, Valerie Daggett
Molecular dynamics (MD) simulations contain considerable information with regard to the motions and fluctuations of a protein, the magnitude of which can be used to estimate conformational entropy. Here we survey conformational entropy across protein fold space using the Dynameomics database, which represents the largest existing data set of protein MD simulations for representatives of essentially all known protein folds. We provide an overview of MD-derived entropies accounting for all possible degrees of dihedral freedom on an unprecedented scale...
April 19, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28368060/controlling-the-plasmonic-orbital-angular-momentum-by-combining-the-geometric-and-dynamic-phases
#16
Qilong Tan, Qinghua Guo, Hongchao Liu, XuGuang Huang, Shuang Zhang
The tunable orbit angular momentum (OAM) of surface plasmon polaritons (SPPs) is theoretically studied with appropriately designed metasurfaces. By controlling both the orientation angle and the spatial position of a nano aperture array on an ultrathin gold film, the field distributions of the surface waves can be engineered to contain both spin dependent and independent OAM components. Simultaneous control over the geometric phase and the optical path difference induced phase (dynamic phase) provides extra degrees of freedom for manipulating the OAM of SPPs...
April 3, 2017: Nanoscale
https://www.readbyqxmd.com/read/28358219/supporting-evidence-informed-teaching-in-biomedical-and-health-professions-education-through-knowledge-translation-an-interdisciplinary-literature-review
#17
Rochelle E Tractenberg, Morris Gordon
Phenomenon: The purpose of "systematic" reviews/reviewers of medical and health professions educational research is to identify best practices. This qualitative article explores the question of whether systematic reviews can support "evidence informed" teaching and contrasts traditional systematic reviewing with a knowledge translation (KT) approach to this objective. APPROACH: Degrees of freedom analysis (DOFA) is used to examine the alignment of systematic review methods with educational research and the pedagogical strategies and approaches that might be considered with a decision-making framework developed to support valid assessment...
March 30, 2017: Teaching and Learning in Medicine
https://www.readbyqxmd.com/read/28349288/genetic-counselors-perception-of-the-effect-on-practice-of-laws-restricting-abortion
#18
Caitlin Cooney, Laura Hercher, Komal Bajaj
In 2013, twenty-two states enacted seventy provisions restricting access to abortion. The legislation restricted access to abortions by instituting more regulations on providers and facilities, by prohibiting abortion prior to viability, by restricting funding available to patients and by requiring patients to wait a mandatory time period before having a procedure. Genetic counselors are trained to provide unbiased, comprehensive information in a non-directive style in order to allow patients to exercise their reproductive freedom...
March 27, 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/28343208/legal-features-of-the-drug-advertising
#19
Vitalii M Pashkov, Andrii A Olefir, Oleksiy Y Bytyak
INTRODUCTION: In the article discribed current trends of advertising in the pharmaceutical market and foreign experience of legal regulation of these relations. As for the advertising of medicines identified it's symptoms, types, basic rules and prohibitions. Modern pharmaceutical companies can not successfully carry out economic activities without advertising. Besides we can mention some fundamental changes in society (information overload, universal access to internet, social media, freedom of movement of goods, labor and finance), also self-medication becomes more popular...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28342521/endovascular-management-of-chronic-symptomatic-aortic-dissection-with-the-streamliner-multilayer-flow-modulator-twelve-month-outcomes-from-the-global-registry
#20
Sherif Sultan, Edel P Kavanagh, Florian Stefanov, Mohamed Sultan, Ala Elhelali, Victor Costache, Edward Diethrich, Niamh Hynes
OBJECTIVE: Reported are initial 12-month outcomes of patients with chronic symptomatic aortic dissection managed by the Streamliner Multilayer Flow Modulator (SMFM; Cardiatis, Isnes, Belgium). Primary end points were freedom from rupture- and aortic-related death, and reduction in false lumen index. Secondary end points were patency of great vessels and visceral branches, and freedom of stroke, paraplegia, and renal failure. METHODS: Out of 876 SMFM implanted globally, we have knowledge of 542...
April 2017: Journal of Vascular Surgery
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