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https://www.readbyqxmd.com/read/29334287/efficacy-and-safety-of-alpha-blockers-in-medical-expulsive-therapy-for-ureteral-stones-a-mixed-treatment-network-meta-analysis-and-trial-sequential-analysis-of-randomized-controlled-clinical-trials
#1
Kannan Sridharan, Gowri Sivaramakrishnan
Alpha blockers (AB) are the main group of drugs used for medical expulsive therapy (MET) in patients with ureteral stones. However, there is no consensus on the relative efficacy and safety of individual AB in MET. Areas covered: The present work is a network meta-analysis of randomized controlled trials comparing AB with either placebo or standard of care in patients with ureteral stones. Electronic databases of Medline, Cochrane CENTRAL and Google Scholar were searched for eligible clinical studies. Inverse variance heterogeneity model was used for mixed treatment comparisons...
January 15, 2018: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/29330940/extracorporeal-shockwave-therapy-for-treatment-of-keloid-scars
#2
Ching-Jen Wang, Jih-Yang Ko, Wen-Yi Chou, Jai-Hong Cheng, Yur-Ren Kuo
The purpose of this investigation was to study the effectiveness of extracorporeal shockwave therapy (ESWT) for the treatment of keloid scars, and compared the results with intralesional steroid injection. Thirty-nine patients were randomly divided into 22 in ESWT group and 17 in steroid group. The ESWT group received 3 ESWT treatments in 6 weeks. The steroid group received 3 intra-lesional triamcinolone injections in 6 weeks. The evaluations included gross morphology, functional outcome, local blood flow perfusion, biopsy for histopathological examination and immunohistochemical analysis...
January 13, 2018: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/29325445/the-morbidity-of-ureteral-strictures-in-patients-with-prior-ureteroscopic-stone-surgery-multi-institutional-outcomes
#3
Philip Clark May, Ryan S Hsi, Henry H Tran, Marshall Stoller, Ben H Chew, Thomas Chi, Manint Usawachintachit, Brian D Duty, John L Gore, Jonathan D Harper
Purpose Nephrolithiasis is an increasingly common ailment in the United States. Ureteroscopic management has supplanted shockwave lithotripsy as the most common treatment of upper tract stone disease. Ureteral stricture is a rare but serious complication of stone disease and its management. The impact of new technologies and more widespread ureteroscopic management on stricture rates is unknown. We describe our experience in managing strictures incurred following ureteroscopy for upper tract stone disease. Materials and methods Records for patients managed at 4 tertiary care centers between December 2006 and October 2015 with the diagnosis of ureteral stricture following ureteroscopy for upper tract stone disease were retrospectively reviewed...
January 12, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29310463/plantar-fibromatosis-pathophysiology-surgical-and-nonsurgical-therapies-an-evidence-based-review
#4
Paul Carroll, Robert M Henshaw, Caitlin Garwood, Katherine Raspovic, Dhruv Kumar
Plantar fibromatosis (morbus Ledderhose), an extra-abdominal desmoid tumor of the plantar foot, is a rare benign hyperproliferative disorder of the plantar fascia with an unknown etiology. The main clinical characteristics include slow growing nodules on the medial and central bands of the plantar fascia, which may become painful and negatively affect ambulation. Most established conservative therapies today target symptomatic relief. As symptoms progress, therapies such as injections, shockwave ablation, radiation, and/or surgery may be required...
January 1, 2018: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/29289980/magnetic-resonance-elastography-can-monitor-changes-in-medullary-stiffness-in-response-to-treatment-in-the-swine-ischemic-kidney
#5
Xin Zhang, Xiangyang Zhu, Christopher Martyn Ferguson, Kai Jiang, Tyson Burningham, Amir Lerman, Lilach Orly Lerman
OBJECTIVE: Low-energy shockwave (SW) therapy attenuates damage in the stenotic kidney (STK) caused by atherosclerotic renal artery stenosis (ARAS). We hypothesized that magnetic resonance elastography (MRE) would detect attenuation of fibrosis following SW in unilateral ARAS kidneys. MATERIALS AND METHODS: Domestic pigs were randomized to control, unilateral ARAS, and ARAS treated with 6 sessions of SW over 3 consecutive weeks (n = 7 each) starting after 3 weeks of ARAS or sham...
December 30, 2017: Magma
https://www.readbyqxmd.com/read/29285980/xenon-protects-against-blast-induced-traumatic-brain-injury-in-an-i-in-vitro-i-model
#6
Rita Campos-Pires, Mariia Koziakova, Amina Yonis, Ashni Pau, Warren Macdonald, Katie Harris, Christopher Edge, Nicholas P Franks, Peter Mahoney, Robert Dickinson
The aim of this study was to evaluate the neuroprotective efficacy of the inert gas xenon as a treatment for blast-induced traumatic brain injury in an in vitro laboratory model. We developed a novel blast traumatic brain injury model using C57BL/6N mouse organotypic hippocampal brain-slice cultures exposed to a single shockwave, with the resulting injury quantified using propidium iodide fluorescence. A shock tube blast generator was used to simulate open field explosive blast shockwaves, modeled by the Friedlander waveform...
December 29, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29284454/the-effect-of-low-intensity-shockwave-treatment-li-swt-on-human-myoblasts-and-mouse-skeletal-muscle
#7
Lise K Hansen, Henrik D Schrøder, Lars Lund, Karthikeyan Rajagopal, Vrisha Maduri, Jeeva Sellathurai
BACKGROUND: Transplanting myogenic cells and scaffolds for tissue engineering in skeletal muscle have shown inconsistent results. One of the limiting factors is neovascularization at the recipient site. Low intensity shockwave therapy (Li-SWT) has been linked to increased tissue regeneration and vascularization, both integral to survival and integration of transplanted cells. This study was conducted to demonstrate the response of myoblasts and skeletal muscle to Li-SWT. METHOD: Primary isolated human myoblasts and explants were treated with low intensity shockwaves and subsequently cell viability, proliferation and differentiation were tested...
December 29, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29275957/effect-of-linear-low-intensity-extracorporeal-shockwave-therapy-for-erectile-dysfunction-12-month-follow-up-of-a-randomized-double-blinded-sham-controlled-study
#8
Grzegorz Lukasz Fojecki, Stefan Tiessen, Palle Jørn Sloth Osther
INTRODUCTION: Short-term data on the effect of low-intensity extracorporeal shockwave therapy (Li-ESWT) on erectile dysfunction (ED) have been inconsistent. The suggested mechanisms of action of Li-ESWT on ED include stimulation of cell proliferation, tissue regeneration, and angiogenesis, which can be processes with a long generation time. Therefore, long-term data on the effect of Li-ESWT on ED are strongly warranted. AIM: To assess the outcome at 6 and 12 months of linear Li-ESWT on ED from a previously published randomized, double-blinded, sham-controlled trial...
December 21, 2017: Sexual Medicine
https://www.readbyqxmd.com/read/29273258/super-mini-percutaneous-nephrolithotomy-for-renal-stone-less-than-25mm-in-pediatric-patients-could-it-be-an-alternative-to-shockwave-lithotripsy
#9
K Sarica, B Eryildirim, A Tuerxun, A Batuer, O Kavukoglu, A Buz, G Zeng
AIM: To evaluate the efficacy of 2 different techniques: shock wave lithotripsy (SWL) vs. super-mini percutaneous nephrolithotomy (SMP), in terms of success as well as complication rates in pediatric renal stones sizing<25mm. PATIENTS AND METHODS: A total of 219 children (aging between 1-17 years) undergoing 2 different treatment modalities (SWL vs. SMP) for kidney stones<25mm were included. Depending on the type of the procedure applied, children were divided into 2 different groups: group 1 (n=108), children treated with SWL, and group 2 (n=111), children treated with SMP...
December 19, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/29245838/dynamic-high-pressure-induced-strong-and-weak-hydrogen-bonds-enhanced-by-pre-resonance-stimulated-raman-scattering-in-liquid-water
#10
Shenghan Wang, Wenhui Fang, Fabing Li, Nan Gong, Zhanlong Li, Zuowei Li, Chenglin Sun, Zhiwei Men
355 nm pulsed laser is employed to excite pre-resonance forward stimulated Raman scattering (FSRS) of liquid water at ambient temperature. Due to the shockwave induced dynamic high pressure, the obtained Raman spectra begin to exhibit double peaks distribution at 3318 and 3373 cm-1 with the input energy of 17 mJ,which correspond with OH stretching vibration with strong and weak hydrogen (H) bonds. With laser energy rising from 17 to 27 mJ, the Stokes line at 3318 cm-1 shifts to 3255 and 3230 cm-1 because of the high pressure being enlarged...
December 11, 2017: Optics Express
https://www.readbyqxmd.com/read/29238665/penile-implants-a-look-into-the-future
#11
REVIEW
Katherine M Rodriguez, Taylor P Kohn, Anthony B Davis, Tariq S Hakky
Inflatable penile prosthesis (IPP) has been around since the 1970's as a durable and one-time cure for erectile dysfunction (ED). For the past 40 years, many changes have been made to make the device better and currently IPP boasts a high percentage of long-term patient satisfaction. The next paradigm shift in IPP treatment for ED is upon us. Funding for ED related medications and devices has been a hot topic in health policy over the last 10 years. This suggests that the device must improve and patient advocacy and education must increase for IPP to remain as a viable solution for ED...
November 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29234533/trends-of-intervention-for-paediatric-stone-disease-over-the-last-two-decades-2000-2015-a-systematic-review-of-literature
#12
REVIEW
Amelia Pietropaolo, Silvia Proietti, Patrick Jones, Karan Rangarajan, Omar Aboumarzouk, Guido Giusti, Bhaskar K Somani
Objective: To ascertain the publication trends of interventions for paediatric kidney stone disease (KSD) we conducted a systematic review of literature over the last 16 years. Patients and methods: With a rise of paediatric KSD and related interventions, a systematic review using PubMed was done over the last 16 years for all published papers on 'Paediatric stone disease intervention - ureteroscopy (URS), shockwave lithotripsy (SWL), percutaneous nephrolithotomy (PCNL), open stone surgery, and laparoscopic stone surgery'...
December 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29234530/a-prospective-randomised-double-blind-placebo-controlled-trial-to-assess-the-effect-of-diuretics-on-shockwave-lithotripsy-of-calculi
#13
Sagar Sabharwal, L Jeyaseelan, Arabind Panda, Lionel Gnanaraj, Nitin S Kekre, Antony Devasia
Objective: To assess the effect of diuretics with shockwave lithotripsy (SWL) on the treatment of renal and upper ureteric calculi. Patients and methods: Adult patients with a solitary non-obstructive radio-opaque renal or upper ureteric calculus with normal renal function were included. They were prospectively randomised to receive either SWL with placebo or SWL with diuretics (40 mg parenteral furosemide) in a double-blind manner with a sample size of 48 patients in each arm...
December 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29232698/low-energy-extracorporeal-shockwave-therapy-eswt-improves-metaphyseal-fracture-healing-in-an-osteoporotic-rat-model
#14
Gina A Mackert, Matthias Schulte, Christoph Hirche, Dimitra Kotsougiani, Julian Vogelpohl, Bernd Hoener, Teresa Fiebig, Stefanie Kirschner, Marc A Brockmann, Marcus Lehnhardt, Ulrich Kneser, Leila Harhaus
PURPOSE: As result of the current demographic changes, osteoporosis and osteoporotic fractures are becoming an increasing social and economic burden. In this experimental study, extracorporeal shock wave therapy (ESWT), was evaluated as a treatment option for the improvement of osteoporotic fracture healing. METHODS: A well-established fracture model in the metaphyseal tibia in the osteoporotic rat was used. 132 animals were divided into 11 groups, with 12 animals each, consisting of one sham-operated group and 10 ovariectomized (osteoporotic) groups, of which 9 received ESWT treatment...
2017: PloS One
https://www.readbyqxmd.com/read/29212688/prognostic-factors-for-the-outcome-of-extracorporeal-shockwave-therapy-for-calcific-tendinitis-of-the-shoulder
#15
W-Y Chou, C-J Wang, K-T Wu, Y-J Yang, J-Y Ko, K-K Siu
AIMS: We conducted a study to identify factors that are prognostic of the outcome of extracorporeal shockwave therapy (ESWT) for calcific tendinitis of the shoulder. PATIENTS AND METHODS: Since 1998, patients with symptomatic calcific tendinitis of the rotator cuff have been treated with ESWT using an electrohydraulic mode shockwave device. One year after ESWT, patients were grouped according to the level of resorption of calcification. RESULTS: Of 241 symptomatic shoulders, complete resorption (CR) of calcification occurred in 134 (CR group)...
December 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/29207984/individualised-radial-extracorporeal-shock-wave-therapy-reswt-for-symptomatic-calcific-shoulder-tendinopathy-a-retrospective-clinical-study
#16
Nikolaos Malliaropoulos, Dawn Thompson, Maria Meke, Debasish Pyne, Dimosthenis Alaseirlis, Henry Atkinson, Vasileios Korakakis, Heinz Lohrer
BACKGROUND: A retrospective single centre cohort analysis was performed to evaluate an individualised radial extracorporeal shock wave therapy (rESWT) protocol for treatment of symptomatic calcific shoulder tendinopathy. METHODS: 67 patients (79 Shoulders) were identified with 76 shoulders included for analysis. rESWT treatment protocol was adapted according to individual response to treatment. Variables included number of sessions, shockwave impulses, pressure and frequency...
December 6, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29205049/extracorporeal-shockwave-lithotripsy-could-lead-to-a-prolonged-increase-in-renal-fibrotic-process-of-up-to-2-years
#17
Chi-Fai Ng, Sylvia Luke, Chi-Hang Yee, Steven Ch Leung, Jeremy Y C Teoh, John Yuen
INTRODUCTION AND OBJECTIVE: This prospective study aimed to evaluate the effect of ramping and pause protocols on renal fibrosis, blood pressure control and renal function in patients receiving extracorporeal shockwave lithotripsy (SWL). METHODS: This study prospectively recruited 320 patients with solitary radiopaque renal stones <15 mm in size. Patients were randomized to receive one of four shockwave protocols: (1) standard protocol (no ramping or pause); (2) ramping protocol alone; (3) ramping and pause protocols or (4) pause protocol alone...
December 5, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29202989/cadaveric-experiments-to-evaluate-pressure-wave-generated-by-radial-shockwave-treatment-of-plantar-fasciitis
#18
Srdjan Cirovic, David H Gould, Derek H Park, Matthew C Solan
BACKGROUND: Shockwave treatment is increasingly used for plantar fasciitis and Achilles tendinopathy. To be effective it is believed that high pressure must be achieved in the tissues. We report on the first human cadaveric experiments to characterize pressure from radial shockwave therapy (rSWT) for plantar fasciitis. METHODS: The pressure from rSWT was measured in two cadaveric feet using a needle hydrophone. Maximal pressure and energy flux were calculated from the measurements...
December 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29201822/effect-of-extracorporeal-shockwave-therapy-versus-intra-articular-injections-of-hyaluronic-acid-for-the-treatment-of-knee-osteoarthritis
#19
June-Kyung Lee, Bong-Yeon Lee, Woo-Yong Shin, Min-Ji An, Kwang-Ik Jung, Seo-Ra Yoon
Objective: To evaluate and compare the effects and outcomes of extracorporeal shock wave therapy (ESWT) and intra-articular injections of hyaluronic acid (HA) in patients with knee osteoarthritis (OA). Methods: Of the 78 patients recruited for the study, 61 patients met the inclusion criteria. The enrolled patients were randomly divided into two groups: the ESWT group and the HA group. The ESWT group underwent 3 sessions of 1,000 shockwave pulses performed on the affected knee with the dosage adjusted to 0...
October 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29197021/how-to-accelerate-the-upper-urinary-stone-discharge-after-extracorporeal-shockwave-lithotripsy-eswl-for%C3%A2-%C3%A2-15%C3%A2-mm-upper-urinary-stones-a-prospective-multi-center-randomized-controlled-trial-about-external-physical-vibration-lithecbole-epvl
#20
Wenqi Wu, Zhou Yang, Fengling Tang, Changbao Xu, Youzhi Wang, Xiaojian Gu, Xuehua Chen, Rongjiang Wang, Jiaka Yan, Xiang Wang, Wenxi Gao, Chunhua Hou, Jianming Guo, Jian Zhang, Alberto Gurioli, Zhangqun Ye, Guohua Zeng
OBJECTIVE: To asset the efficacy and safety of EPVL plus ESWL compared with ESWL alone for the treatment of simple upper urinary stones (< 15 mm). MATERIALS AND METHODS: All patients with upper urinary stones (< 15 mm) were prospectively randomized into two groups. In treatment group, patients were assigned to immediate EPVL after ESWL, while in control group, ESWL alone was offered. All patients were reexamined at 1, 2, and 4 weeks after ESWL. Stone size, stone location, stone-free rate (SFR), and complication rate were compared...
December 1, 2017: World Journal of Urology
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