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https://www.readbyqxmd.com/read/29764036/-comparison-of-prognostic-value-of-18-f-fdg-pet-ct-myocardial-metabolism-imaging-and-coronary-collateral-circulation-in-patients-with-cto-lesions
#1
G Y Zhai, J L Wang, Y Y Liu, Y J Zhou
Objective: To evaluate the location, extent of viable myocardial of chronic total coronary occlusions(CTO)lesions by (18)F-FDG PET myocardial metabolism imaging and then compare with coronary collateral circulation(CCC) to evaluate the prognostic evaluation in patients with CTO lesions. Methods: A total of Sixty consecutive patients with CTO lesions referred for viability assessment from April 2016 to April 2017 in Department of Cardiology, Beijing Anzhen Hospital were included in the study. These patients underwent (99m)Tc-sestamibi ECG-gated SPECT rest myocardial perfusion imaging and ECG-gated (18)F-FDG PET/CT myocardial metabolic imaging, as well as coronary arteriography were recruited in this study...
May 8, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29754928/pathological-mechanisms-of-left-main-stent-failure
#2
Hiroyoshi Mori, Sho Torii, Emanuel Harari, Hiroyuki Jinnouchi, Ryan Brauman, Samantha Smith, Robert Kutys, David Fowler, Maria Romero, Renu Virmani, Aloke V Finn
BACKGROUND: Despite the increasing use of left main (LM) percutaneous coronary intervention (LM-PCI), there have been no pathological studies devoted to understanding the causes of LM stent failure. We aimed to systematically determine the pathological mechanisms of LM stent failure. METHODS AND RESULTS: From the CVPath Stent registry, a total of 46 lesions were identified to have LM-PCI. Pathologic stent failure (PSF) was defined as stent thrombosis, restenosis and in-stent chronic total occlusion (CTO)...
July 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29754161/motion-corrected-whole-heart-pet-mr-for-the-simultaneous-visualisation-of-coronary-artery-integrity-and-myocardial-viability-an-initial-clinical-validation
#3
Camila Munoz, Karl P Kunze, Radhouene Neji, Teresa Vitadello, Christoph Rischpler, René M Botnar, Stephan G Nekolla, Claudia Prieto
PURPOSE: Cardiac PET-MR has shown potential for the comprehensive assessment of coronary heart disease. However, image degradation due to physiological motion remains a challenge that could hinder the adoption of this technology in clinical practice. The purpose of this study was to validate a recently proposed respiratory motion-corrected PET-MR framework for the simultaneous visualisation of myocardial viability (18 F-FDG PET) and coronary artery anatomy (coronary MR angiography, CMRA) in patients with chronic total occlusion (CTO)...
May 12, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29747322/-safety-and-efficacy-of-rotational-atherectomy-in-the-interventional-treatment-of-coronary-chronic-total-occlusion-lesions
#4
J Y Ma, J J Guo, L Hou, F Zhang, K Yao, D Huang, H Lu, Y X Dai, C G Li, S F Chang, Q Qin, L Ge, J Y Qian, J B Ge
Objective: To investigate the safety and efficacy of rotational atherectomy in the interventional treatment of coronary chronic total occlusion lesions. Methods: In this retrospective study,a total of 31 consecutive patients with coronary chronic total occlusion(CTO) lesions underwent rotational atherectomy in our hospital from February 2004 to December 2016 were enrolled,and the clinical features were analyzed. Coronary atherectomy was performed if balloon failed to cross the CTO lesions or balloon could not be fully dilated in the CTO lesions after wire crossing...
April 24, 2018: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29743412/successful-retrieval-of-entrapped-gaia-guidewire-in-calcified-chronic-total-occlusion-using-rotational-atherectomy-device
#5
Jae Young Cho, Soon Jun Hong
We report a novel technique for retrieving an entrapped Gaia guidewires in severely calcified coronary chronic total occlusion (CTO) using a rotational atherectomy device. By successfully cutting the entrapped and untangled guidewire within the CTO with the use of a rotational atherectomy device, we could effectively remove the Gaia guidewire from the right coronary artery.
May 9, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29741489/initial-result-of-angioscopy-guided-wire-crossing-technique-under-continuous-saline-infusion-for-chronic-total-occlusion-in-femoropopliteal-disease
#6
Masamichi Yano, Keisuke Yasumura, Koji Yasumoto, Akihiro Tanaka, Naoki Mori, Daisuke Nakamura, Yasuyuki Egami, Ryu Shutta, Jun Tanouchi, Masami Nishino
AIMS: We occasionally experience endovascular therapy (EVT) failure as a consequence of wire-crossing into the subintima for chronic total occlusion (CTO) in peripheral arteries. Although several reports have demonstrated the importance of accurate wire-crossing into the ostial site of the CTO true lumen to succeed, it is difficult to visualize the CTO ostium before wiring using angiography or intravascular ultrasonography (IVUS). Thus, we directly visualize the ostial sites of lesions and wire manipulation during EVT by angioscopy and evaluate the efficacy and safety of angioscopy-guided EVT under continuous infusion of saline (AGECIS) in peripheral arteries...
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29737030/transcatheter-electrosurgery-in-bipolar-or-monopolar-modes
#7
EDITORIAL
Jaffar M Khan, Robert J Lederman
Transcatheter electrosurgery has emerging value in a range of other new procedures that require traversing tissue (transcaval access, transcatheter Glenn Shunt) or slicing tissue (LAMPOON slicing of the mitral valve and BASILICA slicing of the aortic valve). This is the first report of bipolar radiofrequency wires used to cross lesions in humans, reported here in seven re-entry CTO cases. The bipolar configuration may provide directionality to charge without need for wire alignment and advancement, but is theoretically disadvantageous for tissue "cutting" because of problems with charge concentration...
May 1, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29737029/merely-subintimal-coronary-plaque-modification-improves-health-status-not-all-cto-recanalization-failures-are-alike
#8
EDITORIAL
Carlos M Campos, Pedro A Lemos
Failed CTO angioplasty was divided in two groups: with and without "subintimal plaque modification." At 1-month, patients treated with "subintimal plaque modification" had larger increases in health status as assessed by the Seattle Angina Questionnaire. The relatively small sample size and the lack of a longer follow-up period does not allow definite conclusion in terms of safety or clinical events.
May 1, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29728359/carboxyamidotriazole-orotate-plus-tmz-is-safe-and-active-in-glioblastoma
#9
(no author information available yet)
Carboxyamidotriazole orotate (CTO) plus temozolomide (TMZ) was well tolerated in patients with glioma.
May 4, 2018: Cancer Discovery
https://www.readbyqxmd.com/read/29726047/intravascular-ultrasound-guided-wiring-re-entry-technique-for-complex-chronic-total-occlusions
#10
Wei-Chieh Huang, Hsin-I Teng, Chien-Hung Hsueh, Shing-Jong Lin, Wan-Leong Chan, Tse-Min Lu
BACKGROUND: The successful recanalization rate of chronic total occlusion (CTO) lesions without retrograde collaterals available is always low. Intravascular ultrasound (IVUS) may be useful to guide the subintimal guidewire to re-enter the true lumen. We evaluated the clinical feasibility and efficacy of the IVUS-guided wiring re-entry technique for these complex CTO lesions. METHODS: Twenty consecutive patients (19 male, mean age: 65.3 ± 12.8 years) with both failed antegrade and retrograde approaches were enrolled...
May 3, 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29724974/comparison-of-the-transradial-and-transfemoral-approach-in-treatment-of-chronic-total-occlusions-with-similar-lesion-characteristics
#11
Mustafa Ahmet Huyut, Aylin Hatice Yamaç
OBJECTIVE: There is limited data on the efficacy and the safety of the transradial approach (TRA) for percutaneous coronary intervention (PCI) of chronic total occlusion (CTO), particularly in comparison with the transfemoral approach (TFA) in lesions with similar complexity. METHODS: We included 358 patients, who underwent elective CTO PCI between January 2012 and August 2017 and compared the radial (179 patients) and femoral (179 patients) approaches. The J-CTO score was similar in both groups (TRA, 2...
May 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29722796/a-randomized-multicentre-trial-to-compare-revascularization-with-optimal-medical-therapy-for-the-treatment-of-chronic-total-coronary-occlusions
#12
Gerald S Werner, Victoria Martin-Yuste, David Hildick-Smith, Nicolas Boudou, Georgios Sianos, Valery Gelev, Jose Ramon Rumoroso, Andrejs Erglis, Evald Høj Christiansen, Javier Escaned, Carlo di Mario, Thomas Hovasse, Luis Teruel, Alexander Bufe, Bernward Lauer, Kris Bogaerts, Javier Goicolea, James C Spratt, Anthony H Gershlick, Alfredo R Galassi, Yves Louvard
Aims: The clinical value of percutaneous coronary intervention (PCI) for chronic coronary total occlusions (CTOs) is not established by randomized trials. This study should compare the benefit of PCI vs. optimal medical therapy (OMT) on the health status in patients with at least one CTO. Method and results: Three hundred and ninety-six patients were enrolled in a prospective randomized, multicentre, open-label, and controlled clinical trial to compare the treatment by PCI with OMT with a 2:1 randomization ratio...
May 2, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29720502/evaluation-of-the-impact-of-a-chronic-total-coronary-occlusion-on-ventricular-arrhythmias-and-long-term-mortality-in-patients-with-ischemic-cardiomyopathy-and-an-implantable-cardioverter-defibrillator-the-ectopy-in-icd-study
#13
Ivo M van Dongen, Dilek Yilmaz, Joëlle Elias, Bimmer E P M Claessen, Ronak Delewi, Reinoud E Knops, Arthur A M Wilde, Lieselot van Erven, Martin J Schalij, José P S Henriques
BACKGROUND: Previous studies report conflicting results about a higher incidence of ventricular arrhythmias in patients with a chronic total coronary occlusion (CTO). We aimed to investigate this association in a large cohort of implantable cardioverter defibrillator patients with long-term follow-up. METHODS AND RESULTS: All consecutive patients from 1992 onwards who underwent implantable cardioverter defibrillator implantation for ischemic cardiomyopathy at the Leiden University Medical Center were evaluated...
May 2, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29718894/transradial-percutaneous-coronary-intervention-for-left-main-bifurcation-lesions-using-7-5-fr-sheathless-guide-catheter
#14
Huiqiang Zhao, Subhash Banerjee, Hui Chen, Hongwei Li
Recent studies have shown sheathless guide catheters (GCs) to be safe and effective during complex lesions such as bifurcations, chronic total occlusion (CTO), and/or calcified lesions. We investigated the feasibility and safety of using 7.5-Fr sheathless GC for transradial percutaneous coronary intervention (PCI) to treat left main bifurcation lesions.A total of 82 patients were consecutively enrolled from March 2013 to February 2016. They underwent transradial PCI for left main bifurcation lesions using the 7...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29717512/impact-of-ultra-thin-struts-on-restenosis-after-chronic-total-occlusion-recanalization-insights-from-the-randomized-prison-iv-trial
#15
Carlo Zivelonghi, Koen Teeuwen, Pierfrancesco Agostoni, Renè J van der Schaaf, Flavio Ribichini, Tom Adriaenssens, Johannes C Kelder, Jan G P Tijssen, José P S Henriques, Maarten J Suttorp
OBJECTIVES: The PRISON-IV trial showed inferior outcome in patients with chronic total occlusions (CTOs) treated with the ultrathin-struts (60 μm for stent diameter ≤3 mm, 81μm >3 mm) hybrid-sirolimus eluting stents (SES) compared with everolimus eluting stents (EES, 81 μm). The aim of this study is to investigate if the use of smaller stents (≤3 mm) was responsible for the inferior outcome reported in the trial. METHODS: In the PRISON-IV trial 330 patients with CTO lesion were randomized 1:1 to receive either hybrid-SES or EES...
May 1, 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29713254/long-term-survival-benefit-of-statin-in-patients-with-coronary-chronic-total-occlusion-without-revascularization
#16
Bum Sung Kim, Jeong Hoon Yang, Woo Jin Jang, Young Bin Song, Joo-Yong Hahn, Jin-Ho Choi, Ki Hong Choi, Sung-Hea Kim, Woo Jung Chun, Hyeon-Cheol Gwon, Seung-Hyuk Choi
Background: Limited data are available on the efficacy of statin therapy in stable ischemic heart disease with chronic total occlusion (CTO) without revascularization. We investigated whether statin therapy could be beneficial in stable patients with CTO without revascularization. Methods: From March 2003 to February 2012, 2,024 patients with at least one CTO were enrolled in a retrospective, single-center registry; 664 of these patients were managed conservatively without an initial revascularization strategy...
April 30, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29707284/does-the-hybrid-algorithm-has-real-impact-on-long-term-outcomes-or-should-only-be-used-as-a-valuable-approach-for-cto-crossing
#17
EDITORIAL
Peter Tajti, Emmanouil S Brilakis
No abstract text is available yet for this article.
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29706508/the-hybrid-approach-to-chronic-total-occlusion-percutaneous-coronary-intervention-update-from-the-progress-cto-registry
#18
Peter Tajti, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, Mitul Patel, Ehtisham Mahmud, James W Choi, M Nicholas Burke, Anthony H Doing, Phil Dattilo, Catalin Toma, A J Conrad Smith, Barry Uretsky, Elizabeth Holper, R Michael Wyman, David E Kandzari, Santiago Garcia, Oleg Krestyaninov, Dmitrii Khelimskii, Michalis Koutouzis, Ioannis Tsiafoutis, Jeffrey W Moses, Nicholas J Lembo, Manish Parikh, Ajay J Kirtane, Ziad A Ali, Darshan Doshi, Bavana V Rangan, Imre Ungi, Subhash Banerjee, Emmanouil S Brilakis
OBJECTIVES: The aim of this study was to determine the techniques and outcomes of hybrid chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in a diverse group of patients and operators on 2 continents. BACKGROUND: CTO PCI has been evolving with constant improvement of equipment and techniques. METHODS: Contemporary outcomes of CTO PCI were examined by analyzing the clinical, angiographic, and procedural characteristics of 3,122 CTO interventions performed in 3,055 patients at 20 centers in the United States, Europe, and Russia...
April 24, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29700104/nocturnal-cerebral-hypoxia-in-obstructive-sleep-apnoea-a-randomised-controlled-trial
#19
Esther I Schwarz, Michael Furian, Christian Schlatzer, John R Stradling, Malcolm Kohler, Konrad E Bloch
Objectives. Cerebral hypoxia may promote cerebral damage in patients with obstructive sleep apnoea (OSA). We investigated whether OSA patients experience nocturnal cerebral hypoxia that is prevented by continuous positive airway pressure (CPAP). Methods. OSA patients using CPAP underwent sleep studies including pulse oximetry (SpO2 ) and near-infrared spectroscopy to monitor cerebral tissue oxygenation (CTO) at baseline and after 2 weeks on either subtherapeutic or therapeutic CPAP according to randomised allocation...
April 26, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29695223/what-clinicians-say-about-the-experience-of-working-with-individuals-on-community-treatment-orders
#20
Deborah Corring, Richard L O'Reilly, Christina Sommerdyk, Elizabeth Russell
OBJECTIVE: Community treatment orders (CTOs) refer to a variety of legal schemes that require a person with a serious mental illness to follow a plan of treatment and supervision while living in the community. Use of CTOs has been controversial, and they have been the subject of a considerable amount of quantitative and qualitative research. This article reports the results of a systematic review of qualitative studies focused on understanding the views and experiences of clinicians who work with individuals on CTOs...
April 26, 2018: Psychiatric Services: a Journal of the American Psychiatric Association
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