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Mauricio Gomez

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https://www.readbyqxmd.com/read/28666999/pvhl-suppresses-akt-%C3%AE-catenin-mediated-cell-proliferation-by-inhibiting-14-3-3%C3%AE-%C3%A2-expression
#1
Azucena Castañeda, Carolina Serrano, José Antonio Hernández-Trejo, Itzel Zenidel Gutiérrez-Martínez, Wilber Montejo-López, Mauricio Gómez-Suárez, Marcela Hernández-Ruiz, Abigail Betanzos, Aurora Candelario-Martínez, Hector Romo-Parra, José Antonio Arias-Montaño, Michael Schnoor, Marco Antonio Meraz Ríos, Maria Eugenia Gutierrez-Castillo, Irma Alicia Martínez-Dávila, Nicolás Villegas-Sepúlveda, Daniel Martinez-Fong, Porfirio Nava
The mechanisms controlling degradation of cytosolic β-catenin are important for regulating β-catenin co-transcriptional activity. Loss of pVHL has been shown to stabilize β-catenin, increasing β-catenin transactivation and β-catenin mediated cell proliferation. However, the role of PI3K/Akt in the regulation of β-catenin signaling downstream of pVHL has been never addressed. Here we report that hyperactivation of PI3K/Akt in cells lacking pVHL contributes to the stabilization and nuclear accumulation of active β-catenin...
June 30, 2017: Biochemical Journal
https://www.readbyqxmd.com/read/28617052/neotomodon-alstoni-mice-present-sex-differences-between-lean-and-obese-in-daily-hypothalamic-leptin-signaling
#2
Moisés Pérez-Mendoza, Dalia Luna-Moreno, Agustín Carmona-Castro, Hugo A Rodríguez-Guadarrama, Luis M Montoya-Gómez, Mauricio Díaz-Muñoz, Manuel Miranda-Anaya
This article compared the effects of spontaneous obesity on the daily profile in the relative amount of the leptin receptor (LepRb), and its output. That is the precursor Pro-opiomelanocortin (POMC) over a 24-hour period and compared with differences in locomotion and food intake in periods of artificial light. Differences between lean and obese mice were examined, as were sex differences. Body weight, food intake and locomotor activity were monitored in freely moving lean and obese mice. Hypothalamic tissue was collected at 5 h, 10 h, 15 h, 19 h and 24 h...
June 15, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28610058/a-new-species-of-i-aplectana-i-nematoda-cosmocercidae-parasite-of-i-pleurodema-i-i-nebulosum-i-anura-leptodactylidae-from-the-monte-desert-argentina-with-a-key-to-neotropical-species-of-the-genus-i-aplectana-i
#3
Mauricio D Piñeiro Gomez, Cynthya E González, Eduardo A Sanabria
Here we describe a new cosmocercid nematode, Aplectana nebulosa sp. nov., from the small and large intestines of Pleurodema nebulosum (Anura: Leptodactylidae), from the Monte desert of San Juan, Argentina. The new species belongs to the Aplectana group that possesses a gubernaculum and unpaired adcloacal papilla anteriorly to cloaca. It resembles A. membranosa, A. paraelenae and A. travassosi by the presence of four adcloacal papillae, but differs from those species by the following characters: number and arrangement of precloacal papillae; number and arrangement of postcloacal papillae; shape and size of spicules and gubernaculum, and by the presence of lateral alae in caudal region of males...
March 27, 2017: Zootaxa
https://www.readbyqxmd.com/read/28527274/caracter%C3%A3-sticas-de-la-estructura-molecular-de-las-prote%C3%A3-nas-e-del-virus-del-zika-y-e1-del-virus-de-la-rub%C3%A3-ola-y-posibles-implicaciones-en-el-neurotropismo-y-en-las-alteraciones-del-sistema-nervioso
#4
Luis Alberto Gómez, Gladis Montoya, Hernán Mauricio Rivera, Juan Carlos Hernández
Introducción. El virus del Zika (ZIKV) es un flavivirus con envoltura, transmitido a los seres humanos principalmente por el vector Aedes aegypti. La infección por ZIKV se ha asociado con un gran neurotropismo y con efectos neuropáticos, como el síndrome de Guillain-Barré en el adulto y la microcefalia fetal y posnatal, así como con un síndrome de infección congénita similar al producido por el virus de la rubéola (RV).Objetivo. Comparar las estructuras moleculares de la proteína de envoltura E del virus del Zika (E-ZIKV) y de la E1 del virus de la rubéola (E1-RV), y plantear posibles implicaciones en el neurotropismo y en las alteraciones del sistema nervioso asociadas con el ZIKV...
April 1, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/28465870/is-legionellosis-present-and-important-in-colombia-an-analyses-of-cases-from-2009-to-2013
#5
Andrés Mauricio Patiño-Barbosa, Andrés Felipe Gil-Restrepo, Valentina Restrepo-Montoya, Wilmer E Villamil-Gomez, Jaime A Cardona-Ospina, Alfonso J Rodriguez-Morales
Infection due to Legionella pneumophila has been not studied in Colombia, although it is present. The observational, retrospective study in which the incidence of legionellosis in Colombia, 2009-2013, was estimated based on data extracted from the personal health records system (Registro Individual de Prestación de Servicios, RIPS) using the ICD-10 codes A48.1 (Legionnaires' disease) and A48.2 (Pontiac Fever). Using official population estimates of the National Administrative Department of Statistics (DANE), crude and adjusted incidence rates were estimated (cases / 100,000 pop)...
March 28, 2017: Curēus
https://www.readbyqxmd.com/read/28459203/leptin-acts-on-neoplastic-behavior-and-expression-levels-of-genes-related-to-hypoxia-angiogenesis-and-invasiveness-in-oral-squamous-cell-carcinoma
#6
Eliane Macedo Sobrinho Santos, Talita Antunes Guimarães, Hércules Otacílio Santos, Lilian Mendes Borborema Cangussu, Sabrina Ferreira de Jesus, Carlos Alberto de Carvalho Fraga, Claudio Marcelo Cardoso, Sérgio Henrique Souza Santos, Alfredo Maurício Batista de Paula, Ricardo Santiago Gomez, André Luiz Sena Guimarães, Lucyana Conceição Farias
Leptin, one of the main hormones controlling energy homeostasis, has been associated with different cancer types. In oral cancer, its effect is not well understood. We investigated, through in vitro and in vivo assays, whether leptin can affect the neoplastic behavior of oral squamous cell carcinoma. Expression of genes possibly linked to the leptin pathway was assessed in leptin-treated oral squamous cell carcinoma cells and also in tissue samples of oral squamous cell carcinoma and oral mucosa, including leptin, leptin receptor, hypoxia-inducible factor 1-alpha, E-cadherin, matrix metalloproteinase-2, matrix metalloproteinase-9, Col1A1, Ki67, and mir-210...
May 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28424063/clinical-and-cost-effectiveness-analysis-of-early-detection-of-patients-at-nutrition-risk-during-their-hospital-stay-through-the-new-screening-method-cipa-a-study-protocol
#7
RANDOMIZED CONTROLLED TRIAL
José Pablo Suárez-Llanos, Néstor Benítez-Brito, Laura Vallejo-Torres, Irina Delgado-Brito, Adriá Rosat-Rodrigo, Carolina Hernández-Carballo, Yolanda Ramallo-Fariña, Francisca Pereyra-García-Castro, Juan Carlos-Romero, Nieves Felipe-Pérez, Jennifer García-Niebla, Eduardo Mauricio Calderón-Ledezma, Teresa de Jesús González-Melián, Ignacio Llorente-Gómez de Segura, Manuel Ángel Barrera-Gómez
BACKGROUND: Malnutrition is highly prevalent in hospitalized patients and results in a worsened clinical course as well as an increased length of stay, mortality, and costs. Therefore, simple nutrition screening systems, such as CIPA (control of food intake, protein, anthropometry), may be implemented to facilitate the patient's recovery process. The aim of this study is to evaluate the effectiveness and cost-effectiveness of implementing such screening tool in a tertiary hospital, consistent with the lack of similar, published studies on any hospital nutrition screening system...
April 20, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28362260/evolution-of-substrate-specificity-in-a-retained-enzyme-driven-by-gene-loss
#8
Ana Lilia Juárez-Vázquez, Janaka N Edirisinghe, Ernesto A Verduzco-Castro, Karolina Michalska, Chenggang Wu, Lianet Noda-García, Gyorgy Babnigg, Michael Endres, Sofía Medina-Ruíz, Julián Santoyo-Flores, Mauricio Carrillo-Tripp, Hung Ton-That, Andrzej Joachimiak, Christopher S Henry, Francisco Barona-Gómez
The connection between gene loss and the functional adaptation of retained proteins is still poorly understood. We apply phylogenomics and metabolic modeling to detect bacterial species that are evolving by gene loss, with the finding that Actinomycetaceae genomes from human cavities are undergoing sizable reductions, including loss of L-histidine and L-tryptophan biosynthesis. We observe that the dual-substrate phosphoribosyl isomerase A or priA gene, at which these pathways converge, appears to coevolve with the occurrence of trp and his genes...
March 31, 2017: ELife
https://www.readbyqxmd.com/read/28321383/direct-endonasal-approach-with-partial-upper-posterior-septectomy-a-rescue-flap-technique-modification
#9
Arturo Sotomayor-González, Armando José Díaz-Martínez, Ramón Radillo-Gil, Everardo García-Estrada, Jesús Alberto Morales-Gómez, Isaac Jair Palacios-Ortiz, Samuel Pérez-Cárdenas, Mauricio Arteaga-Treviño, Ángel Martínez-Ponce De León
Objective Report a modification of the "rescue flap" technique using a direct endonasal approach with a partial superior septectomy for approaching pituitary tumors developed in our institution. Design Prospective study. Setting Hospital Universitario "Dr. José Eleuterio González," Universidad Autónoma de Nuevo León. Main Outcome Measures Since April 2015, we have performed 19 cases employing a direct endonasal approach with partial superior septectomy. Results and a technical note are described below...
April 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28293043/treatment-of-post-transplantation-lymphoproliferative-disorders-after-kidney-transplant-with-rituximab-and-conversion-to-m-tor-inhibitor
#10
John Fredy Nieto-Rios, Sandra Milena Gómez de Los Ríos, Lina María Serna-Higuita, Catalina Ocampo-Kohn, Arbey Aristizabal-Alzate, Kenny Mauricio Gálvez-Cárdenas, Gustavo Adolfo Zuluaga-Valencia
BACKGROUND: Post-transplantation lymphoproliferative disorders are serious complications of organ transplantation which treatment is not yet standardized. OBJECTIVE: To describe the clinical response, overall and graft survival of patients in our center with this complication after kidney transplantation, which received rituximab as part of their treatment as well as conversion to m-TOR. METHODS: Retrospective study, which included patients, diagnosed with post-transplant lymphoproliferative disorders after kidney transplantation from January 2011 to July 2014...
December 30, 2016: Colombia Médica: CM
https://www.readbyqxmd.com/read/28289213/new-middle-pleistocene-hominin-cranium-from-gruta-da-aroeira-portugal
#11
Joan Daura, Montserrat Sanz, Juan Luis Arsuaga, Dirk L Hoffmann, Rolf M Quam, María Cruz Ortega, Elena Santos, Sandra Gómez, Angel Rubio, Lucía Villaescusa, Pedro Souto, João Mauricio, Filipa Rodrigues, Artur Ferreira, Paulo Godinho, Erik Trinkaus, João Zilhão
The Middle Pleistocene is a crucial time period for studying human evolution in Europe, because it marks the appearance of both fossil hominins ancestral to the later Neandertals and the Acheulean technology. Nevertheless, European sites containing well-dated human remains associated with an Acheulean toolkit remain scarce. The earliest European hominin crania associated with Acheulean handaxes are at the sites of Arago, Atapuerca Sima de los Huesos (SH), and Swanscombe, dating to 400-500 ka (Marine Isotope Stage 11-12)...
March 28, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28287494/synthetic-peptides-derived-from-bovine-lactoferricin-exhibit-antimicrobial-activity-against-e-coli-atcc-11775-s-maltophilia-atcc-13636-and-s-enteritidis-atcc-13076
#12
Nataly De Jesús Huertas Méndez, Yerly Vargas Casanova, Anyelith Katherine Gómez Chimbi, Edith Hernández, Aura Lucia Leal Castro, Javier Mauricio Melo Diaz, Zuly Jenny Rivera Monroy, Javier Eduardo García Castañeda
Linear, dimeric, tetrameric, and cyclic peptides derived from lactoferricin B-containing non-natural amino acids and the RWQWR motif were synthesized, purified, and characterized using RP-HPLC, MALDI-TOF mass spectrometry, and circular dichroism. The antibacterial activity of peptides against Escherichia coli ATCC 11775, Stenotrophomonas maltophilia ATCC 13636, and Salmonella enteritidis ATCC 13076 was evaluated. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined...
March 12, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28170445/validation-of-masimo-pronto-7-and-hemocue-201-for-hemoglobin-determination-in-children-from-1-to-5-years-of-age
#13
Teresa Shamah Levy, Ignacio Méndez-Gómez-Humarán, María Del Carmen Morales Ruán, Brenda Martinez Tapia, Salvador Villalpando Hernández, Mauricio Hernández Ávila
OBJECTIVE: To evaluate the accuracy and precision of HemoCue 201 (HemoCue) and Masimo Pronto 7 (Masimo) devices for measuring hemoglobin (Hb) in epidemiological studies, having venous blood samples as a gold standard. MATERIAL AND METHODS: We measured Hb concentrations in a field sample of 148 children from one to five years of age. Masimo and HemoCue were used for capillary blood samples and an automatic analyzer for venous blood samples. Regression models with no intercept were constructed to measure precision and predictability, concordance correlations to measure accuracy and precision, and Bland-Altman limits of agreement as well as hierarchical linear models to estimate variance...
2017: PloS One
https://www.readbyqxmd.com/read/28156050/evaluation-of-a-decision-support-strategy-for-the-control-of-powdery-mildew-erysiphe-necator-schw-burr-in-grapevine-in-the-central-region-of-chile
#14
Héctor Valdés-Gómez, Miguel Araya-Alman, Carolina Pañitrur-De la Fuente, Nicolás Verdugo-Vásquez, Mauricio Lolas, César Acevedo-Opazo, Christian Gary, Agnès Calonnec
BACKGROUND: The primary strategy to control powdery mildew in Chilean vineyards involves periodic fungicide spraying, which may lead to many environmental and human health risks. This study aimed to implement and evaluate the effectiveness and economic feasibility of a novel Decision Support Strategy (DSS) to limit the number of treatments against this pathogen. An experiment was conducted between the 2010 and 2013 seasons in two irrigated vine fields, one containing a cultivar of Cabernet Sauvignon (CS) and another of Chardonnay (CH)...
February 3, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28128541/fenestrated-and-chimney-endovascular-aneurysm-repair-versus-open-surgery-for-complex-abdominal-aortic-aneurysms
#15
Vicente A Sala-Almonacil, José M Zaragozá-García, Mauricio Ramírez-Montoya, Vicente Molina-Nácher, Inmaculada Martínez-Perelló, Francisco J Gómez-Palonés
BACKGROUND: Many patients with complex abdominal aortic aneurysms are unfit for open repair. New endovascular technologies and bailout techniques are being used for managing those complex anatomies. The purpose of this study is to compare the results obtained with advanced endovascular aneurysm repair techniques (fenestrated and chimney endografts) to those obtained with open repair for the treatment of complex abdominal aortic aneurysms not anatomically suitable for standard endovascular exclusion (infrarenal neck <10 mm, juxtarenal, suprarenal and Crawford's type IV thoracoabdominal aneurysms)...
January 27, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28069520/conditioned-medium-from-persistently-rsv-infected-macrophages-alters-transcriptional-profile-and-inflammatory-response-of-non-infected-macrophages
#16
Evelyn Rivera-Toledo, Iván Salido-Guadarrama, Mauricio Rodríguez-Dorantes, Laura Torres-González, Carlos Santiago-Olivares, Beatriz Gómez
Cells susceptible to persistent viral infections undergo important changes in their biological functions as a consequence of the expression of viral gene products that are capable of altering the gene expression profile of the host cell. Previously, we reported that persistence of the RSV genome in a mouse macrophage cell line induces important alterations in cell homeostasis, including constitutive expression of IFN-β and other pro-inflammatory cytokines. Here, we postulated that changes in the homeostasis of non-infected macrophages could be induced by soluble factors secreted by persistently RSV- infected macrophages...
January 6, 2017: Virus Research
https://www.readbyqxmd.com/read/28012556/-crossed-renal-ectopia-in-a-patient-with-a-complicated-sigma-neoplasia
#17
Luis Eduardo Pérez-Sánchez, Mauricio Burneo-Esteves, Adriá Rosat-Rodrigo, Caleb Baz-Figueroa, Antonio Dámaso Pérez-Álvarez, Manuel Ángel Barrera-Gómez
BACKGROUND: Crossed renal ectopia is a rare pathology that is often asymptomatic. Intraoperative detection with a sigma complicated neoplasia is more infrequent and requires correct management to avoid a renal ureteral injury. AIM: To present a case report of a patient with a sigma complicated neoplasia and a crossed renal ectopia detected incidentally. CASE REPORT: We present the case of a 62-year-old man that was submitted for emergency surgery for a sigma perforated neoplasm, and who presented with a previously undiagnosed left-side CRE...
December 21, 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/28001445/long-term-efficacy-and-safety-of-sensor-augmented-insulin-pump-therapy-with-low-glucose-suspend-feature-in-patients-with-type-1-diabetes
#18
Ana María Gómez, Lisseth Fernanda Marín Carrillo, Oscar Mauricio Muñoz Velandia, Martín Alonso Rondón Sepúlveda, Carol M Arévalo Correa, Edwin Mora Garzón, Maria Camila Cuervo Diaz, Diana Cristina Henao Carrillo
BACKGROUND: Literature supports short-term efficacy and safety of Sensor Augmented Insulin Pump (SAP) therapy in patients with type 1 diabetes (T1D). However, no data are available showing long-term outcomes. Our study describes the long-term outcomes of SAP therapy with low-glucose suspend feature (SAP+LGS) in hypoglycemia in a Colombian population with T1D and hypoglycemia. METHODS: A cohort study was conducted with T1D patients receiving SAP+LGS therapy who initiated this therapy because of hypoglycemia at San Ignacio University Hospital diabetes center in Bogotá, Colombia...
February 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/27993257/-depression-and-anxiety-disorders-and-associated-factors-in-the-adult-colombian-population-2015-national-mental-health-survey
#19
Carlos Gómez-Restrepo, Nathalie Tamayo Martínez, Adriana Bohórquez, Martín Rondón, Mauricio Medina Rico, Hernet Rengifo, Nubia Bautisa
INTRODUCTION: Mental disorders are the first causes of disability adjusted life years (DALY), contributing with the 7.4%. This value increases as the DALYs of the transmittable diseases decrease. OBJECTIVES: To determine the prevalence and associated factors of the major depressive and anxious disorders. METHODS: Data obtained from the IV Mental Health Survey with representation from 5 regions. A computerised interview was conducted, focusing on the most frequent anxiety and depressive disorders, using the CIDI CAPI 3...
December 2016: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/27993256/-depression-and-anxiety-disorders-and-associated-factors-in-the-adolescent-colombian-population-2015-national-mental-health-survey
#20
Carlos Gómez-Restrepo, Adriana Bohórquez, Nathalie Tamayo Martínez, Martín Rondón, Nubia Bautista, Herney Rengifo, Mauricio Medina Rico
INTRODUCTION: There was a prevalence of mental disorders of 17% in adolescents in the past year. These tended to be chronic and their appearance at this age is associated with a worse prognosis than those in adulthood. OBJECTIVES: To determine the prevalence and mental factors associated with major depression and anxiety disorders. METHODS: Data were obtained from the IV National Mental Health Survey representing 5 regions. A structured computerised survey was conducted using the Computer Assisted Personal Interview-Composite International Diagnostic Interview-Adolescent Version (CAPI-CIDI-A), focused on the most common depression and anxiety disorders...
December 2016: Revista Colombiana de Psiquiatría
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