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https://www.readbyqxmd.com/read/29786947/does-general-experience-affect-self-assessment
#1
Parisa Rezaiefar, Kelly Forse, Joseph K Burns, Sharon Johnston, Elizabeth Muggah, Claire Kendall, Douglas Archibald
BACKGROUND: The assessment of clinical competence is critical in medical education. Understanding the effect of general experience on a physician's self-assessment would help design more effective curricula and evaluations of procedural skills in postgraduate training and continuing professional development (CPD). In this observational study, we assessed the effect of general experience on the correlation between confidence and competence amongst experienced clinicians (ECs) and postgraduate trainees (PGTs) when learning an office-based procedure in pessary care...
May 22, 2018: Clinical Teacher
https://www.readbyqxmd.com/read/29786886/predictors-of-treatment-completion-for-families-referred-to-trauma-focused-cognitive-behavioral-therapy-after-child-abuse
#2
Marianne Celano, Amanda NeMoyer, Anna Stagg, Nikia Scott
Despite advances in the dissemination of evidence-based therapy for abuse-related traumatic stress, many referred children fail to complete treatment. Using archival data from a sample of children participating in trauma-focused cognitive behavioral therapy (TF-CBT) at a hospital-based child advocacy center, analyses explored the impact of baseline child traumatic stress symptoms, a second (nonprimary) caregiver's treatment attendance, and the number of assessment sessions on treatment completion while controlling for demographic variables...
May 22, 2018: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29786839/the-influence-of-scalded-flour-fermentation-and-plants-belonging-to-lamiaceae-family-on-the-wheat-bread-quality-and-acrylamide-content
#3
Elena Bartkiene, Vadims Bartkevics, Vita Krungleviciute, Iveta Pugajeva, Daiva Zadeike, Grazina Juodeikiene, Dalia Cizeikiene
The aim of this study was to investigate the influence of additives such as plants belonging to Lamiaceae family (Thymus vulgaris, Carum carvi, Origanum vulgare, Ocimum basilicum, and Coriandrum sativum), scalded flour (SF) or scalded flour fermented with Lactobacillus plantarum LUHS135 (SFFLp) on the quality and acrylamide formation in wheat bread. The formation of acrylamide and bread quality significantly depended on the king of plants used and the amount of SF and SFFLp used. The additives of T. vulgaris and SF increased the content of acrylamide by 3...
May 22, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29786817/targeted-cardiopulmonary-resuscitation-training-focused-on-the-family-members-of-high-risk-patients-at-a-regional-medical-center-a-comparison-between-family-members-of-high-risk-and-no-risk-patients
#4
Kap Su Han, Ji Sung Lee, Su Jin Kim, Sung Woo Lee
BACKGROUND: We developed a hospital-based cardiopulmonary resuscitation (CPR) training model focused on the target population (family members of patients with potential risks for cardiac arrest) and compared the outcome of CPR training between target and non-target populations for validity. METHODS: Family members of patients in training were divided into three groups on the basis of patients' diseases, as follows: 1) the cardio-specific (CS) risk group, including family members of patients with cardiac disease at risk of cardiac arrest; 2) the cardiovascular (CV) risk group, including family members of patients with risk factors for cardiovascular disease; and 3) the no-risk group...
May 2018: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29786791/protocols-for-studies-on-tmprss2-erg-in-prostate-cancer
#5
Hubert Pakula, Douglas E Linn, Daniel R Schmidt, Marit Van Gorsel, Matthew G Vander Heiden, Zhe Li
TMPRSS2/ERG is the most common type of gene fusions found in human prostate cancer. There are two important features of TMPRSS2/ERG fusions. One is that these gene fusions lead to ectopic expression of ERG, an ETS family transcription factor, in prostate epithelial cells from the 5' control region of an androgen/estrogen dual-responsive gene, TMPRSS2; the other is that ~60% of these fusions are generated via intrachromosomal deletion of the interstitial region between TMPRSS2 and ERG. To recapitulate these important aspects of TMPRSS2/ERG fusions, we generated several TMPRSS2/ERG knockin mouse models based on the endogenous Tmprss2 locus...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29786780/correction-to-the-italian-version-of-the-juvenile-arthritis-multidimensional-assessment-report-jamar
#6
Alessandro Consolaro, Francesca Bovis, Angela Pistorio, Rolando Cimaz, Fabrizio De Benedetti, Angela Miniaci, Fabrizia Corona, Valeria Gerloni, Silvana Martino, Serena Pastore, Patrizia Barone, Sara Pieropan, Elisabetta Cortis, Rosa Anna Podda, Romina Gallizzi, Adele Civino, Francesco La Torre, Donato Rigante, Rita Consolini, Maria Cristina Maggio, Silvia Magni-Manzoni, Francesca Perfetti, Giovanni Filocamo, Claudia Toppino, Francesco Licciardi, Marco Garrone, Silvia Scala, Elisa Patrone, Monica Tonelli, Daniela Tani, Angelo Ravelli, Alberto Martini, Nicolino Ruperto
The family name of author Francesco La Torre was incorrect in the published article. The correct family name should read as La Torre F.
May 21, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29786762/chronic-conditions-and-multimorbidity-in-a-primary-care-population-a-study-in-the-swiss-sentinel-surveillance-network-sentinella
#7
Markus Gnädinger, Lilli Herzig, Alessandro Ceschi, Dieter Conen, Alfred Staehelin, Marco Zoller, Milo A Puhan
OBJECTIVES: To provide estimates of the prevalence of chronic conditions in Swiss primary care. METHODS: In total, 175 general practitioners (GP) or pediatricians (PED) reporting to the Swiss Sentinel Surveillance Network collected morbidity data. RESULTS: In 26,853 patient contacts, mean (± SD) age was 55.8 ± 21.6 or 6.1 ± 5.7 years (in GPs vs. PEDs, respectively) and 47% were males. In GP patients, median Thurgau Morbidity Index was 2 (IQR 1-3)...
May 21, 2018: International Journal of Public Health
https://www.readbyqxmd.com/read/29786744/mir%C3%A2-133b-regulates-proliferation-and-apoptosis-in-high%C3%A2-glucose%C3%A2-induced-human-retinal-endothelial-cells-by-targeting-ras-homolog-family-member-a
#8
Jun Yao, Jihong Wang, Yong Yao, Kelei Wang, Qianqian Zhou, Ying Tang
The aim of the present study was to investigate the role of microRNA (miR)‑133b in high‑glucose‑induced human retinal endothelial cells (hRECs), particularly regarding its potential targeting of ras homolog family member A (RhoA). To establish the high‑glucose‑induced diabetic retinopathy (DR) model, hRECs were cultured in high‑glucose medium for 1, 2 and 3 days. An Annexin allophycocyanin (APC)/7‑aminoactinomycin D (7‑AAD) staining assay was performed to measure the apoptosis of hRECs. Next, the cells were transfected with miR‑133b inhibitors or mimics, and the cell proliferation and apoptosis were measured by MTT and Annexin‑APC/7‑AAD staining assays, respectively...
May 18, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29786687/genome-wide-analysis-of-circular-rnas-in-bovine-cumulus-cells-treated-with-bmp15-and-gdf9
#9
Yao Fu, Hao Jiang, Jian-Bo Liu, Xu-Lei Sun, Zhe Zhang, Sheng Li, Yan Gao, Bao Yuan, Jia-Bao Zhang
Circular RNAs (circRNAs) are important members of the non-coding RNA family, and those relating to animal physiologies have been widely studied in recent years. This study aimed to explore the roles of circRNAs in the regulation of follicular development. We constructed four bovine cumulus cell cDNA libraries, including a negative control group (NC) and groups treated with BMP15, GDF9 and BMP15 + GDF9, and we sequenced the libraries on the Illumina HiSeq Xten platform. We identified 1706 circRNAs and screened for differential circRNA expression...
May 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29786666/dopamine-receptor-subtypes-differentially-regulate-autophagy
#10
Dongmei Wang, Xinmiao Ji, Juanjuan Liu, Zhiyuan Li, Xin Zhang
Some dopamine receptor subtypes were reported to participate in autophagy regulation, but their exact functions and mechanisms are still unclear. Here we found that dopamine receptors D2 and D3 (D2-like family) are positive regulators of autophagy, while dopamine receptors D1 and D5 (D1-like family) are negative regulators. Furthermore, dopamine and ammonia, the two reported endogenous ligands of dopamine receptors, both can induce dopamine receptor internalization and degradation. In addition, we found that AKT (protein kinase B)-mTOR (mechanistic target of rapamycin) and AMPK (AMP-activated protein kinase) pathways are involved in DRD3 (dopamine receptor D3) regulated autophagy...
May 22, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29786606/crystal-and-magnetic-structure-of-antiferromagnetic-mn-sub-2-sub-ptpd
#11
Vivek Kumar, Manfred Reehuis, Andreas Hoser, Peter Adler, Claudia Felser
We have investigated the crystal and magnetic structure of Mn<sub>2</sub>PtPd alloy using powder X-ray and neutron diffraction experiments. This compound is believed to belong to the Heusler family having crystal symmetry I4/mmm (TiAl<sub>3</sub>-type). However, in this work we found that the Pd and Pt atoms are disordered and thus Mn<sub>2</sub>PtPd crystallizes in the L1<sub>0</sub> structure having P4/mmm symmetry (CuAu-I type) like MnPt and MnPd binary alloys...
May 22, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29786597/-the-sexuality-of-woman-in-puerperium
#12
Barbara Kalbarczyk, Marcin Bobiński, Mieczysław Szatanek, Bartłomiej Kalbarczyk, Robert Rojewski, Jan Kotarski
After the birth various physical, hormonal and psychological changes affect women's emotional status. These significantly impact their family life including the quality of sexual relationships. Among these factors the method of birth, hormonal changes, breast feeding and incidence of postpartal depression are considered to affect relations with the partner. Unfortunately the sexuality in this special time in women's life is commonly avoided or underestimated both by woman and doctors.
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786593/reproductive-function-the-protection-of-the-rights-of-the-people-which-are-sent-to-the-area-of-the-fighting
#13
Vitalii Pashkov, Nataliya Gutorova, Petro Noha
OBJECTIVE: Introduction: The issues of problems of the legal regulation of posthumous reproduction in Ukraine and foreign countries are analysis in the article. The author substantiates the necessity in the creation and acceptance of the State Program of the retrieval of reproductive cells in people who are sending to the area of the fighting. The aim:the purpose of our work is a comprehensive study of post-mortem (post-mortem) reproduction and substantiation of the possibility and necessity of adopting a state program for the selection of reproductive cells of individuals who are sent to a combat zone to ensure their full social protection and assistance in the realization of the right to fatherhood or motherhood...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786592/obstetric-and-gynecological-care-by-family-doctors-in-ukraine-literature-review
#14
Oksana V Bakun, Svitlana Y Karatieieva, Svitlana B Semenenko, Oksana I Yurkiv, Ksenia V Slobodian
OBJECTIVE: Introduction: The analysis of literature on the questions of obstetrical and gynecologic care by general practitioners - family doctors in Ukraine has been presented in the article. Special attention has been paid to the actual problems of primary health care implementation on the basis of family medicine. The aim of the study is to find out the depth of the problem "A female doctor as an obstetrician-gynecologist" by analyzing scientific relevant literature data...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786581/development-of-informational-communicative-system-created-to-improve-medical-help-for-family-medicine-doctors
#15
Vladyslav A Smiianov, Natalia O Dryha, Olha I Smiianova, Victor K Obodyak, Tatyana O Zudina
OBJECTIVE: Introduction: Today mobile health`s protection service has no concrete meaning. As an research object it was called mHealth and named by Global observatory of electronic health`s protection as "Doctor and social health practice that can be supported by any mobile units (mobile phones or smartphones), units for patient`s health control, personal computers and other units of non-wired communication". An active usage of SMS in programs for patients` cure regimen keeping was quiet predictable...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786512/-kidney-full-of-stones-and-an-adrenal-gland-not-quite-normal
#16
S Regnier Le Coz, D Drui
A 31-year-old patient was followed for cystinuria, justifying CT scans. In 2006, a tissue mass of 3cm of the right adrenal gland, homogeneous, measured at 3.5cm in 2007 was noted. Blood pressure was 90/61mmHg, without orthostatic hypotension. During the clinical interview, no discomfort, sweat attack, headache, or palpitation was reported by the patient. Hormonal assays did not favor a primary hyperaldosteronism, or a hypercortisolism. Adrenal androgens were normal. 24h normetanephrines urinary excretion and metanephrines to creatinine ratio were elevated...
May 18, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29786509/-targeted-screening-for-pre-eclampsia-in-the-first-trimester-of-pregnancy-at-toulouse-university-hospital
#17
A Genoux, P Guerby, M Morin, B Perret, C Vayssière, S M Hamdi
GOALS: Preeclampsia (PE) is a leading cause of maternal and neonatal morbidity and mortality. Early treatment by aspirin has been shown to significantly reduce PE risk before 37weeks supporting the implementation of first-trimester screening. SUBJECTS AND METHODS: A targeted screening was recently implemented at Toulouse University Hospital for women in their first pregnancy or those with personal or familial history of PE. It uses Fetal Medicine Foundation (FMF) algorithm that combines maternal characteristics, clinical, biophysical and biochemical (PAPP-A, Pregnancy Associated Plasma Protein-A, and PlGF, Placental Growth Factor) data...
May 18, 2018: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29786501/strategies-to-increase-filipino-american-participation-in-cardiovascular-health-promotion-a-systematic-review
#18
Jermy-Leigh B Domingo, Gretchenjan Gavero, Kathryn L Braun
INTRODUCTION: Cultural tailoring of interventions can be effective in reducing health disparities by attracting underserved populations to health promotion programs and improving their outcomes. The purpose of this systematic review was to assess what is known about increasing access to and participation in cardiovascular disease (CVD) prevention and control programs among Filipino Americans. METHODS: PubMed MEDLINE, CINAHL, and Sociologic Abstracts were searched for peer-reviewed studies and dissertations conducted in the United States from 2004 through 2016...
May 17, 2018: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29786427/diallyl-trisulfide-induces-apoptosis-of-human-papillary-thyroid-carcinoma-bcpap-cells-through-activating-mapk-signaling-pathway
#19
Jie Pan, Li Zhang, Shichen Xu, Xian Cheng, Huixin Yu, Jiandong Bao, Rong-Rong Lu
This study aimed to elucidate the potential effects of diallyl trisulfide (DATS) on human papillary thyroid carcinoma BCPAP cells and its underling mechanisms. DATS is one of the organosulfur compounds which derived from garlic. In this study, we demonstrated that compared to the solvent control, DATS treatment at concentrations of 5, 10 and 20 μΜ decreased cell survival rate of BCPAP cells to 84.51 ± 2.67%, 57.16 ± 1.18%, 41.22 ± 1.19% respectively. DATS also caused cell cycle arrest at G0/G1 phase and the proportion of cells arrested in G0/G1 phase rose from 68...
May 22, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29786190/-identification-of-a-new-mutation-of-the-nphp1-gene
#20
Antonella La Russa, Rosa Anna Cifarelli, Anna Perri, Angelo Saracino, Giovanni Santarsia, Renzo Bonofiglio
Kidney cystic diseases are inherited disorders causing chronic renal failure. According to the genetic defect they are classified as diseases of the primary ciliary complex and uromodulin-associated diseases. Mutations in genes coding for ciliary proteins are the basis of a broad category of genetic diseases, called ciliopathies. To date, three important ciliopathies are known: the autosomal dominant form and the recessive shape of the polycystic kidney and the nephronophthisis (NPHP). Juvenile Nephronophthisis (NPHP) is a progressive renal tubulo-interstitial disorder with a form of autosomal recessive inheritance that progresses inexorably towards terminal renal failure...
May 2018: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
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