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https://www.readbyqxmd.com/read/28543801/characterisation-of-pomegranate-husk-polyphenols-and-semi-preparative-fractionation-of-punicalagin
#1
Pedro Aguilar-Zárate, Jorge E Wong-Paz, Mariela Michel, Juan Buenrostro-Figueroa, Hugo R Díaz, Juan A Ascacio, Juan C Contreras-Esquivel, Gerardo Gutiérrez-Sánchez, Cristóbal N Aguilar
INTRODUCTION: Pomegranate-husk is the main by-product generated from the pomegranate industry. It is a potential source of compounds highly appreciated by different costumers. Punicalagin is the main compound present in pomegranate-husk. OBJECTIVE: To characterise the pomegranate-husk total polyphenols by HPLC-ESI-MS and to establish a method for the recovery of punicalagin using a medium pressure liquid chromatography (MPLC) system. MATERIALS AND METHODS: The characterisation of total pomegranate-husk polyphenols was carried out using liquid chromatography coupled to mass spectrometry...
May 23, 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28539200/-two-dimensional-molecularly-imprinted-solid-phase-extraction-coupled-with-crystallization-and-high-performance-liquid-chromatography-for-fast-semi-preparative-purification-of-tannins-from-pomegranate-husk-extract
#2
Guangying Sun, Yanfang Liu, Hasanjan Ahat, Aijin Shen, Xinmiao Liang, Xingya Xue, Yuqin Luo, Jian Yang, Zhao-Sheng Liu, Haji Akber Aisa
In this study, "two dimensional" molecularly imprinted solid-phase extraction (2D-MIP-SPE) of semi-preparative grade was constructed to fast purify ellagitannins in pomegranate husk extract with the help of crystallization and reverse-phase liquid chromatgoraphy (RPLC). Ellagic acid and punicalagin imprinted polymers were synthesized in batch mode and two semi-preparative MIP-SPE columns were individually packed. After investigaing "functional complementation", 2D-MIP-SPE was constructed using ellagic acid MIP and punicalagin MIP-SPE as the first and second dimension, respectively...
May 15, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28524381/antifungal-activity-of-gallic-acid-in-vitro-and-in-vivo
#3
Zhi-Jian Li, Meng Liu, Gulina Dawuti, Qin Dou, Yu Ma, Heng-Ge Liu, Silafu Aibai
Gallic acid (GA) is a polyphenol natural compound found in many medicinal plant species, including pomegranate rind (Punica granatum L.), and has been shown to have antiinflammatory and antibacterial properties. Pomegranate rind is used to treat bacterial and fungal pathogens in Uyghur and other systems of traditional medicine, but, surprisingly, the effects of GA on antifungal activity have not yet been reported. In this study, we aimed to investigate the inhibitory effects of GA on fungal strains both in vitro and in vivo...
May 19, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28513179/consumption-of-watermelon-juice-enriched-in-l-citrulline-and-pomegranate-ellagitannins-enhanced-metabolism-during-physical-exercise
#4
Ascensión Martínez-Sánchez, Fernando Alacid, Jacobo A Rubio-Arias, Bárbara Fernández-Lobato, Domingo J Ramos-Campo, Encarna Aguayo
l-Citrulline is a nonessential amino acid precursor of arginine and indirectly a precursor of nitric oxide (NO), which is a vasodilator and increases mitochondrial respiration. On the other hand, the antioxidant pomegranate ellagitannins are precursors of urolithin A, which has been associated with mitophagy and increased muscle function. To elucidate if a single dose of watermelon enrichment with these compounds could have a positive effect after high-intensity exercise (eight sets of eight repetitions of half-squat exercise), a double-blind randomized crossover in vivo study was performed in healthy male subjects (n = 19)...
May 26, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28500980/serum-metabolomics-reveals-the-mechanistic-role-of-functional-foods-and-exercise-for-obesity-management-in-rats
#5
Naglaa M Ammar, Mohamed A Farag, Tahani E Kholeif, Nadia S Metwally, Nora M El-Sheikh, Abdel Nasser El Gendy, Abdel-Hamid Z Abdel-Hamid
Obesity is one of the independent risk factors for several health problems, leading to metabolic perturbations and for which analytical approaches i.e., "metabolomics" is needed to monitor the underlying metabolic changes. In this study, obesity associated changes were assessed via serum metabolites analysis of obese rats fed on high fat diet. Obese rats were subsequently treated with different functional foods used for obesity management including pomegranate, grapefruit, and red cabbage in parallel to swimming exercise...
May 1, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28490140/evaluation-of-antioxidant-capacity-and-flavor-profile-change-of-pomegranate-wine-during-fermentation-and-aging-process
#6
Yongli Lan, Jin Wu, Xuejiao Wang, Xuchun Sun, Robert M Hackman, Zhixi Li, Xianchao Feng
Antioxidant properties and flavor characteristic profile of pomegranate wine during winemaking were investigated. The total phenol content and radical scavenging activity exhibited a slightly decrease in the end edge. Punicalagins and gallic acid were revealed to be the most abundant phenolic compounds, followed by ellagic acid and vanillic acid. These constituents were mainly responsible for the effective antioxidant capacity of pomegranate wine. The major changes of flavor qualities occurred in the initial stage, particularly 0-4day of fermentation...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28490133/nano-zno-carboxymethyl-cellulose-based-active-coating-impact-on-ready-to-use-pomegranate-during-cold-storage
#7
Mahmoud Koushesh Saba, Rasoul Amini
Minimally processed pomegranate rapidly loses its overall quality because of high water loss and microbial contamination. Nano-ZnO in combination with carboxymethyl cellulose (CMC) coating was used on pomegranate arils. Arils were dipped for 4min in distilled water (control), 0.1 or 0.2% (w/v) nano-ZnO suspension and then ZnO treated arils were coated with 0.5% (w/v) CMC and stored for 12days at 4°C. Coatings decreased total yeast+mold during 12days of storage while total mesophilic bacteria was decreased during 6days of storage...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28490079/influence-of-osmotic-dehydration-pre-treatment-and-combined-drying-method-on-physico-chemical-and-sensory-properties-of-pomegranate-arils-cultivar-mollar-de-elche
#8
Marina Cano-Lamadrid, Krzysztof Lech, Anna Michalska, Malwina Wasilewska, Adam Figiel, Aneta Wojdyło, Ángel A Carbonell-Barrachina
"Mollar de Elche" is the most popular Spanish pomegranate cultivar (intense sweetness and easy-to-chew arils); however, arils have pale pink colour and flat sensory profile. "Mollar the Elche" arils first underwent an osmotic dehydration pre-treatment (OD) with concentrated juices: (i) chokeberry, (ii) apple, and/or (iii) pomegranate cultivar "Wonderful", to improve their antioxidant capacity, colour, and sensory profile complexity, and later the arils were dried by a combined method (convective pre-drying+vacuum microwave finish drying)...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28485441/fibre-fortification-of-wheat-bread-impact-on-mineral-composition-and-bioaccessibility
#9
Zita E Martins, Edgar Pinto, Agostinho A Almeida, Olívia Pinho, Isabel M P L V O Ferreira
In this work, wheat bread was fortified with fibre enriched extracts recovered from agroindustry by-products, namely, elderberry skin, pulp and seeds (EE); orange peel (OE); pomegranate peel and interior membranes (PE); and spent yeast (YE). The impact of this fortification on the total and bioaccessible mineral composition of wheat breads, estimated mineral daily intake, and the relationship between bioaccessibility and dietary fibre was evaluated. Fortification with OE, EE, and PE improved the content of essential minerals in bread when compared to control bread...
May 24, 2017: Food & Function
https://www.readbyqxmd.com/read/28475151/antimicrobial-optical-and-mechanical-properties-of-chitosan-starch-films-with-natural-extracts
#10
Jessica I Lozano-Navarro, Nancy P Díaz-Zavala, Carlos Velasco-Santos, Ana L Martínez-Hernández, Beatriz I Tijerina-Ramos, Margarita García-Hernández, José L Rivera-Armenta, Ulises Páramo-García, Adriana I Reyes-de la Torre
Natural extracts possess several kinds of antioxidants (anthocyanins, betalains, thymol, carvacrol, and resveratrol) that have also demonstrated antimicrobial properties. In order to study these properties, extracts from cranberry, blueberry, beetroot, pomegranate, oregano, pitaya, and resveratrol (from grapes) were obtained. Growth inhibition tests of mesophilic aerobes, coliforms, and fungi were conducted in films prepared from the extracts in accordance with Mexican Official Norms (NOM). Optical properties such as transparency and opacity, mechanical properties, and pH were also analyzed in these materials...
May 5, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28461721/responses-of-pomegranate-cultivars-to-severe-water-stress-and-recovery-changes-on-antioxidant-enzyme-activities-gene-expression-patterns-and-water-stress-responsive-metabolites
#11
Mohammadreza Pourghayoumi, Majid Rahemi, Davood Bakhshi, Ali Aalami, Ali Akbar Kamgar-Haghighi
The biochemical and molecular responses of five commercially well-known pomegranate cultivars to severe water stress were studied. The cultivars were subjected to 14-day water stress by withholding irrigation, followed by re-watering for 7 days. Results showed clear differences in metabolites contents and activities of antioxidant enzymes among various pomegranate cultivars during severe water stress and recovery. According to our results, increased accumulation of proline in pomegranate was not related to osmotic adjustment during severe water stress...
April 2017: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
https://www.readbyqxmd.com/read/28460925/willingness-to-pay-more-for-value-added-pomegranate-juice-punica-granatum-l-an-open-ended-contingent-valuation
#12
Karen Rodrigues Romano, Fernanda Dias Bartolomeu Abadio Finco, Amauri Rosenthal, Marcus Vinicius Alves Finco, Rosires Deliza
This study aimed at estimating the consumer's willingness to pay (WTP) more for value-added pomegranate juice using the contingent valuation method (CVM). The WTP was estimated applying the open-ended elicitation technique with 454 consumers in two supermarkets located in Rio de Janeiro, Brazil. The average consumer's WTP more for pomegranate juice was estimated in R$2.04 (Brazilian currency) and the income elasticity coefficient at the midpoint was 0.19, i.e., a 10% increase in consumer income will increase, on average, 1...
November 2016: Food Research International
https://www.readbyqxmd.com/read/28460121/evaluation-of-natural-additives-to-enhance-the-persistence-of-spodoptera-littoralis-lepidoptera-noctuidae-nucleopolyhedrovirus-splimnpv-under-field-conditions-in-saudi-arabia
#13
Koko Dwi Sutanto, Said El Salamouny, Muhammad Tufail, Khawaja Ghulam Rasool, Sukirno Sukirno, Merle Shepard, Martin Shapiro, Abdulrahman Saad Aldawood
Nucleopolyhedrovirus is an effective biocontrol agent but for its biggest disadvantage of short persistence under sunlight conditions. In this study, 10 plant extracts were evaluated as ultraviolet (UV) protectants to improve the persistence of Spodoptera littoralis multiple-embedded nucleopolyhedrovirus (SpliMNPV) against cotton leafworm (Spodoptera littoralis Boisduval). In the primary lab screening test, 5 out of 10 additives (cloves, henna, green tea, pomegranate, and grape extracts) presented a high rate of virus protection with original activity remaining (OAR) percentage of 100%, 97%, 91%, 90...
June 1, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28456359/the-use-of-countercurrent-chromatography-in-the-separation-of-nonpolar-lipid-compounds
#14
Walter Vetter, Simon Hammann, Marco Müller, Michael Englert, Yining Huang
Isolation of lipophilic compounds by countercurrent chromatography (CCC) is a challenge because biphasic solvent systems in which these compounds distribute evenly are difficult to obtain. In this article we present novel applications of lipid compound isolation from natural sources. Conjugated linolenic acids (CLnAs, log KOW ∼7) were isolated from pomegranate oil using a solvent system consisting of n-heptane/methanol/water 100:91:9 (v/v/v). The CLnA fraction was free of other fatty acids but consisted of different isomers which were not resolved from each other...
April 15, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28456146/comparative-effects-of-a-fixed-polypodium-leucotomos-pomegranate-combination-versus-polypodium-leucotomos-alone-on-skin-biophysical-parameters
#15
Enzo Emanuele, Marco Bertona, Marco Biagi
OBJECTIVES: Polypodium leucotomos extract is a commonly used systemic photoprotective agent. In an exploratory fashion, the current study aimed to compare the effects of oral supplementation with a fixed Polypodium leucotomos/pomegranate combination (PPmix®) versus Polypodium leucotomos alone (Fernblock®) on skin biophysical parameters of Caucasian adults. METHODS: Forty healthy adult volunteers (20 males and 20 females; mean age: 37.2±5.5 years) were randomized in a 1:1 fashion to a fixed Polypodium leucotomos/pomegranate combination (480 mg/day; n=20) or Polypodium leucotomos alone (480 mg/day; n=20) for 3 months...
February 15, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28452959/anti-inflammatory-mechanism-involved-in-pomegranate-mediated-prevention-of-breast-cancer-the-role-of-nf-%C3%AE%C2%BAb-and-nrf2-signaling-pathways
#16
Animesh Mandal, Deepak Bhatia, Anupam Bishayee
Pomegranate (Punica granatum L.), a nutrient-rich unique fruit, has been used for centuries for the prevention and treatment of various inflammation-driven diseases. Based on our previous study, a characterized pomegranate emulsion (PE) exhibited a striking inhibition of dimethylbenz(a)anthracene (DMBA)-initiated rat mammary tumorigenesis via antiproliferative and apoptosis-inducing mechanisms. The objective of the present work is to investigate the anti-inflammatory mechanism of action of PE during DMBA rat mammary carcinogenesis by evaluating the expression of cyclooxygenase-2 (COX-2), heat shock protein 90 (HSP90), nuclear factor-κB (NF-κB) and nuclear factor erythroid 2p45 (NF-E2)-related factor 2 (Nrf2)...
April 28, 2017: Nutrients
https://www.readbyqxmd.com/read/28440320/a-review-of-pomegranate-in-prostate-cancer
#17
REVIEW
C J Paller, A Pantuck, M A Carducci
BACKGROUND: Preclinical studies showing that pomegranate juice and its components inhibit prostate cancer led to multiple clinical trials to determine whether pomegranate products could slow the growth of prostate cancer. This review summarizes the preclinical data and discusses the results of the clinical trials. METHODS: Trials targeted patients on active surveillance, neoadjuvant patients, patients with biochemical recurrence (BCR) following local therapy for prostate cancer, and patients with metastatic castration-resistant prostate cancer (mCRPC)...
April 25, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/28435369/in-vitro-comparative-evaluation-of-different-storage-media-hank-s-balanced-salt-solution-propolis-aloe-vera-and-pomegranate-juice-for-preservation-of-avulsed-tooth
#18
Prashant Babaji, Mahesh Melkundi, Raghu Devanna, B S Suresh, Vishwajit Rampratap Chaurasia, P V Gopinath
OBJECTIVES: Prognosis of the avulsed teeth is mostly affected by extraoral dry period and storage medium used to store teeth before reimplantation. However, ability of storage media can affect cell viability and success of treatment. Various storage media were tried with some success. The present study was undertaken to comparatively evaluate the efficacy of hank's balanced salt solution (HBSS), propolis, Aloe vera, and pomegranate juice (PJ) in preserving the vitality of periodontal ligament (PDL) cells of avulsed teeth...
January 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28428773/mutation-at-g103-of-mtbftsz-altered-their-sensitivity-to-coumarins
#19
Duggirala Sridevi, Karpagam U Sudhakar, Ragamanvitha Ananthathatmula, Rakesh P Nankar, Mukesh Doble
Coumarins are natural polyphenol lactones comprising of fused rings of benzene and α-pyrone. The current study demonstrates the inhibitory effect of coumarins with various substitutions on Mycobacterium smegmatis mc(2) 155. We also demonstrate the effect of pomegranate (Punica granatum) extract containing ellagic acid, on M. smegmatis as well as their affect on MtbFtsZ (FtsZ from Mycobacterium tuberculosis). The ellagic acid extracts from pomegranate peels inhibit mycobacteria with a MIC of 25 μM and 0.3 to 3...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28425868/pomegranate-as-a-possible-treatment-in-reducing-risk-of-developing-wound-healing-obesity-neurodegenerative-disorders-and-diabetes-mellitus
#20
Manaf AlMatar, Md Rashedul Islam, Othman Albari, Işıl Var, Fatih Köksal
Four distinguished although overlying stages make up the methodical procedure of wound healing, which are hemostasis, inflammation, proliferation and remodelling. Multiple sclerosis (MS) comprises a persistent inflammatory infection of the central nervous system, and is related to demyelination, neurodegeneration, as well as susceptibility to oxidative pressure. Obesity signifies a swiftly developing danger to the wellbeing of populations in a rising number of nations. Usually called diabetes mellitus (DM) by medical practitioners, diabetes details a collection of metabolic diseases within which the individual has raised blood glucose, either due to an insufficiency of insulin generation, or the lack of suitable response by the body to insulin, or both...
April 19, 2017: Mini Reviews in Medicinal Chemistry
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