keyword
MENU ▼
Read by QxMD icon Read
search

DALY

keyword
https://www.readbyqxmd.com/read/28731893/validity-of-administrative-data-in-identifying-cancer-related-events-in-adolescents-and-young-adults-a-population-based-study-using-the-impact-cohort
#1
Sumit Gupta, Paul C Nathan, Nancy N Baxter, Cindy Lau, Corinne Daly, Jason D Pole
BACKGROUND: Despite the importance of estimating population level cancer outcomes, most registries do not collect critical events such as relapse. Attempts to use health administrative data to identify these events have focused on older adults and have been mostly unsuccessful. We developed and tested administrative data-based algorithms in a population-based cohort of adolescents and young adults with cancer. METHODS: We identified all Ontario adolescents and young adults 15-21 years old diagnosed with leukemia, lymphoma, sarcoma, or testicular cancer between 1992-2012...
July 20, 2017: Medical Care
https://www.readbyqxmd.com/read/28731178/microrna-379-acts-as-a-tumor-suppressor-in-non-small-cell-lung-cancer-by-targeting-the-igf%C3%A2-1r-mediated-akt-and-erk-pathways
#2
Fangzheng Zhou, Long Nie, Dali Feng, Siyan Guo, Ren'na Luo
Lung cancer is one of the most common types of malignancy in humans and is a leading cause of cancer-related deaths among men and women worldwide. Aberrantly expressed microRNAs in non-small cell lung cancer (NSCLC) contribute to tumor occurrence and development as either tumor suppressors or promoters. MicroRNA-379 (miR‑379) is dysregulated in several types of human cancer. However, its expression pattern, role and underlying mechanism in NSCLC progression and metastasis are poorly understood. In this study, assay of reverse transcription-quantitative polymerase chain reaction showed that miR‑379 was downregulated in both NSCLC tissue and cell lines...
July 18, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28730301/biopsychosocial-factors-predict-quality-of-life-in-thoracolumbar-spine-surgery
#3
Dean A Tripp, Edward Abraham, Maude Lambert, Kate Wagg, Erin Bigney, Eden Daly, Phylicia Verreault, Neil Manson
PURPOSE: Surgical intervention is a treatment option for various spinal pathology but many patients report no improvement or even an exacerbation of symptoms like pain. This study examined the association of preoperative (pre-op) biopsychosocial risk factors with poor quality of life at 2 and 6 months using hierarchical models controlling demographic and medical variables. METHOD: Participants undergoing thoracolumbar spine surgery (N = 214) were provided with questionnaire packages to complete pre-op, at 2 and at 6-month postoperative clinical follow-ups (i...
July 20, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28729627/a-mechanism-based-qstr-model-for-acute-to-chronic-toxicity-extrapolation-a-case-study-of-antibiotics-on-luminous-bacteria
#4
Dali Wang, Yue Gu, Min Zheng, Wei Zhang, Zhifen Lin, Ying Liu
The determination of the chronic toxicity is time-consumed and costly, so it's of great interest to predict the chronic toxicity based on acute data. Current methods include the acute to chronic ratios (ACRs) and the QSTR models, both of which have some usage limitations. In this paper, the acute and chronic mixture toxicity of three types of antibiotics, namely sulfonamides, sulfonamide potentiators and tetracyclines, were determined by a bioluminescence inhibition test. A novel QSTR model was developed for predicting the chronic mixture toxicity using the acute data and docking-based descriptors...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28728580/lumbar-microdiscectomy-and-post-operative-activity-restrictions-a-protocol-for-a-single-blinded-randomised-controlled-trial
#5
Chris D Daly, Kai Zheong Lim, Jennifer Lewis, Kelly Saber, Mohammed Molla, Naor Bar-Zeev, Tony Goldschlager
BACKGROUND: Lumbar microdiscectomy is the most commonly performed spinal surgery procedure, with over 300,000 cases performed annually in the United States alone. Traditionally, patients were advised to restrict post-operative activity as this was believed to reduce the risk of disc reherniation and progressive instability. However, this practice would often delay patients return to work. In contemporary practice many surgeons do not restrict patient post-operative activity due to the perception this practice is unnecessary...
July 20, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28728152/use-of-the-putamen-as-a-surrogate-anatomical-marker-for-the-internal-segment-of-the-globus-pallidus-in-deep-brain-stimulation-surgery
#6
John A Thompson, Dali Yin, Steven G Ojemann, Aviva Abosch
OBJECTIVE: The success of deep brain stimulation (DBS) of the internal segment of the globus pallidus (GPi) depends on accurately placing the electrode into the GPi motor territory. Direct targeting can be difficult as GPi laminar borders are not always clearly identifiable on MRI. Here, we report a method for using the putamen (PUT) as a surrogate anatomical marker to target the GPi. METHODS: We developed a PUT-based GPi targeting using the FGATIR (fast gray matter acquisition T1-weighted inversion recovery) MRI sequence and compared it with consensus coordinate-based indirect targeting...
July 21, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28727576/severe-respiratory-failure-extracorporeal-membrane-oxygenation-and-intracranial-hemorrhage
#7
Christopher J A Lockie, Stuart A Gillon, Nicholas A Barrett, Daniel Taylor, Asif Mazumder, Kaggere Paramesh, Katie Rowland, Kathleen Daly, Luigi Camporota, Christopher I S Meadows, Guy W Glover, Nicholas Ioannou, Christopher J Langrish, Stephen Tricklebank, Andrew Retter, Duncan L A Wyncoll
OBJECTIVES: For patients supported with veno-venous extracorporeal membrane oxygenation, the occurrence of intracranial hemorrhage is associated with a high mortality. It is unclear whether intracranial hemorrhage is a consequence of the extracorporeal intervention or of the underlying severe respiratory pathology. In a cohort of patients transferred to a regional severe respiratory failure center that routinely employs admission brain imaging, we sought 1) the prevalence of intracranial hemorrhage; 2) survival and neurologic outcomes; and 3) factors associated with intracranial hemorrhage...
July 19, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28725165/cost-effectiveness-of-pre-referral-antimalarial-treatment-in-severe-malaria-among-children-in-sub-saharan-africa
#8
Vivian Rakuomi, Faith Okalebo, Stanley Ndwigah, Levi Mbugua
BACKGROUND: In 2013, 78% of malaria deaths occurred in children aged 5 years and below, in sub-Saharan Africa. Treatment of severe malaria requires a health facility with inpatient care. However, in most sub-Sahara African countries, access to health facilities is a major problem. Pre-referral antimalarial treatments aim to delay the progress of severe malaria as patients seek to access health facilities. Rectal artesunate can be administered in the community as a pre-referral treatment in rural hard-to-reach areas...
2017: Cost Effectiveness and Resource Allocation: C/E
https://www.readbyqxmd.com/read/28722009/highly-variable-recurrence-of-tsunamis-in-the-7-400-years-before-the-2004-indian-ocean-tsunami
#9
Charles M Rubin, Benjamin P Horton, Kerry Sieh, Jessica E Pilarczyk, Patrick Daly, Nazli Ismail, Andrew C Parnell
The devastating 2004 Indian Ocean tsunami caught millions of coastal residents and the scientific community off-guard. Subsequent research in the Indian Ocean basin has identified prehistoric tsunamis, but the timing and recurrence intervals of such events are uncertain. Here we present an extraordinary 7,400 year stratigraphic sequence of prehistoric tsunami deposits from a coastal cave in Aceh, Indonesia. This record demonstrates that at least 11 prehistoric tsunamis struck the Aceh coast between 7,400 and 2,900 years ago...
July 19, 2017: Nature Communications
https://www.readbyqxmd.com/read/28721837/effects-of-progressive-resistance-training-combined-with-a-protein-enriched-lean-red-meat-diet-on-health-related-quality-of-life-in-elderly-women-secondary-analysis-of-a-4-month-cluster-randomised-controlled-trial
#10
Susan J Torres, Sian Robinson, Liliana Orellana, Stella L O'Connell, Carley A Grimes, Niamh L Mundell, David W Dunstan, Caryl A Nowson, Robin M Daly
Resistance training (RT) and increased dietary protein are recommended to attenuate age-related muscle loss in the elderly. This study examined the effect of a lean red meat protein-enriched diet combined with progressive resistance training (RT+Meat) on health-related quality of life (HR-QoL) in elderly women. In this 4-month cluster randomised controlled trial, 100 women aged 60-90 years (mean 73 years) from self-care retirement villages participated in RT twice a week and were allocated either 160 g/d (cooked) lean red meat consumed across 2 meals/d, 6 d/week or ≥1 serving/d (25-30 g) carbohydrates (control group, CRT)...
June 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28720003/current-trends-in-the-management-of-ballistic-fractures-of-the-hand-and-wrist-experiences-of-a-high-volume-level-i-trauma-center
#11
Paul A Ghareeb, Charles Daly, Albert Liao, Diane Payne
BACKGROUND: Ballistic fractures of the carpus and hand are routinely treated in large urban centers. These injuries can be challenging due to many factors. Various treatment options exist for these complicated injuries, but there are limited data available. This report analyzes patient demographics, treatments, and outcomes at a large urban trauma center. METHODS: All ballistic fractures of the hand and wrist of the patients who presented to a single center from 2011 to 2014 were retrospectively reviewed...
March 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28719574/ancient-european-dog-genomes-reveal-continuity-since-the-early-neolithic
#12
Laura R Botigué, Shiya Song, Amelie Scheu, Shyamalika Gopalan, Amanda L Pendleton, Matthew Oetjens, Angela M Taravella, Timo Seregély, Andrea Zeeb-Lanz, Rose-Marie Arbogast, Dean Bobo, Kevin Daly, Martina Unterländer, Joachim Burger, Jeffrey M Kidd, Krishna R Veeramah
Europe has played a major role in dog evolution, harbouring the oldest uncontested Palaeolithic remains and having been the centre of modern dog breed creation. Here we sequence the genomes of an Early and End Neolithic dog from Germany, including a sample associated with an early European farming community. Both dogs demonstrate continuity with each other and predominantly share ancestry with modern European dogs, contradicting a previously suggested Late Neolithic population replacement. We find no genetic evidence to support the recent hypothesis proposing dual origins of dog domestication...
July 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/28719263/burden-of-disease-attributed-to-waterborne-transmission-of-selected-enteric-pathogens-australia-2010
#13
Katherine B Gibney, Joanne O'Toole, Martha Sinclair, Karin Leder
AbstractUniversal access to safe drinking water is a global priority. To estimate the annual disease burden of campylobacteriosis, nontyphoidal salmonellosis, cryptosporidiosis, giardiasis, and norovirus attributable to waterborne transmission in Australia, we multiplied regional World Health Organization (WHO) estimates of the proportion of cases attributable to waterborne transmission by estimates of all-source disease burden for each study pathogen. Norovirus was attributed as causing the most waterborne disease cases (479,632; 95% uncertainty interval [UI]: 0-1,111,874) followed by giardiasis and campylobacteriosis...
June 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28715457/an-analogous-wood-barrel-theory-to-explain-the-occurrence-of-hormesis-a-case-study-of-sulfonamides-and-erythromycin-on-escherichia-coli-growth
#14
Dali Wang, Zhifen Lin, Ting Wang, Xiruo Ding, Ying Liu
Hormesis has aroused much attention during the past two decades and may have great implications on many fields, including toxicology and risk assessment. However, the observation of hormesis remains challenged under laboratory conditions. To determine favorable conditions under which to observe hormesis, we investigated the hormetic responses of Escherichia coli (E. coli) upon exposure of different concentrations of sulfonamides and erythromycin at different time points and in different culture media: Luria-Bertani (LB) broth and Mueller Hinton (MH) broth...
2017: PloS One
https://www.readbyqxmd.com/read/28714722/pilot-testing-the-daily-activities-list-for-inmates-dali-item-evaluation-and-content-validity
#15
Philip R Magaletta, Rokas Perskaudas, Christina J Connors, Marc W Patry, Jarrod Reisweber, Alix McLearen
Scheduling enjoyable daily activities is a Cognitive Behavioral Therapy intervention used in the treatment of depression and substance abuse disorders that are prevalent disorders among inmates. To effectively use this intervention with inmates, an activities list with items ecologically sensitive to the correctional setting needs to be created. The purpose of this study was to develop and evaluate items; thus, establishing a content valid Daily Activities List for Inmates (DALI). Fifteen corrections professionals representing a wide range of disciplines and managerial backgrounds served as subject matter experts (SMEs)...
July 17, 2017: Psychological Services
https://www.readbyqxmd.com/read/28708963/a-qualitative-study-adopting-a-user-centered-approach-to-design-and-validate-a-brain-computer-interface-for-cognitive-rehabilitation-for-people-with-brain-injury
#16
Suzanne Martin, Elaine Armstrong, Eileen Thomson, Eloisa Vargiu, Marc Solà, Stefan Dauwalder, Felip Miralles, Jean Daly Lynn
Cognitive rehabilitation is established as a core intervention within rehabilitation programs following a traumatic brain injury (TBI). Digitally enabled assistive technologies offer opportunities for clinicians to increase remote access to rehabilitation supporting transition into home. Brain Computer Interface (BCI) systems can harness the residual abilities of individuals with limited function to gain control over computers through their brain waves. This paper presents an online cognitive rehabilitation application developed with therapists, to work remotely with people who have TBI, who will use BCI at home to engage in the therapy...
July 14, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/28708899/the-cost-effectiveness-of-a-quality-improvement-program-to-reduce-maternal-and-fetal-mortality-in-a-regional-referral-hospital-in-accra-ghana
#17
David M Goodman, Rohit Ramaswamy, Marc Jeuland, Emmanuel K Srofenyoh, Cyril M Engmann, Adeyemi J Olufolabi, Medge D Owen
OBJECTIVE: To evaluate the cost-effectiveness of a quality improvement intervention aimed at reducing maternal and fetal mortality in Accra, Ghana. DESIGN: Quasi-experimental, time-sequence intervention, retrospective cost-effectiveness analysis. METHODS: Data were collected on the cost and outcomes of a 5-year Kybele-Ghana Health Service Quality Improvement (QI) intervention conducted at Ridge Regional Hospital, a tertiary referral center in Accra, Ghana, focused on systems, personnel, and communication...
2017: PloS One
https://www.readbyqxmd.com/read/28703323/professional-oral-healthcare-for-preventing-nursing-home-acquired-pneumonia-a-cost-effectiveness-and-value-of-information-analysis
#18
Falk Schwendicke, Michael Stolpe, Frauke Müller
AIM: Professional oral healthcare (POHC) prevents nursing-home-acquired pneumonia (NHAP) and its related mortality. We assessed the cost-effectiveness of POHC versus no POHC (nPOHC) and the monetary value of eliminating uncertainty by future research. METHODS: German public-private-payer-perspective was adopted. A Markov-model was used, following Long-Term-Care residents from admission to death. Cost-effectiveness was estimated as Euro/disability-adjusted-life-year (DALY) using Monte-Carlo microsimulations...
July 13, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28702810/epidemiology-of-gestational-diabetes-mellitus-according-to-iadpsg-who-2013-criteria-among-obese-pregnant-women-in-europe
#19
Aoife M Egan, Akke Vellinga, Jürgen Harreiter, David Simmons, Gernot Desoye, Rosa Corcoy, Juan M Adelantado, Roland Devlieger, Andre Van Assche, Sander Galjaard, Peter Damm, Elisabeth R Mathiesen, Dorte M Jensen, Liselotte Andersen, Annuziata Lapolla, Maria G Dalfrà, Alessandra Bertolotto, Urszula Mantaj, Ewa Wender-Ozegowska, Agnieszka Zawiejska, David Hill, Judith G M Jelsma, Frank J Snoek, Christof Worda, Dagmar Bancher-Todesca, Mireille N M van Poppel, Alexandra Kautzky-Willer, Fidelma P Dunne
AIMS/HYPOTHESIS: Accurate prevalence estimates for gestational diabetes mellitus (GDM) among pregnant women in Europe are lacking owing to the use of a multitude of diagnostic criteria and screening strategies in both high-risk women and the general pregnant population. Our aims were to report important risk factors for GDM development and calculate the prevalence of GDM in a cohort of women with BMI ≥29 kg/m(2) across 11 centres in Europe using the International Association of the Diabetes and Pregnancy Study Groups (IADPSG)/WHO 2013 diagnostic criteria...
July 12, 2017: Diabetologia
https://www.readbyqxmd.com/read/28698327/bubble-continuous-positive-airway-pressure-in-the-treatment-of-severe-paediatric-pneumonia-in-malawi-a-cost-effectiveness-analysis
#20
Teresa Bleakly Kortz, Benjamin Herzel, Elliot Marseille, James G Kahn
OBJECTIVES: Pneumonia is the largest infectious cause of death in children under 5 years globally, and limited resource settings bear an overwhelming proportion of this disease burden. Bubble continuous positive airway pressure (bCPAP), an accepted supportive therapy, is often thought of as cost-prohibitive in these settings. We hypothesise that bCPAP is a cost-effective intervention in a limited resource setting and this study aims to determine the cost-effectiveness of bCPAP, using Malawi as an example...
July 10, 2017: BMJ Open
keyword
keyword
18150
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"