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https://www.readbyqxmd.com/read/29135948/effect-of-a-lactobacillus-salivarius-probiotic-on-a-double-species-streptococcus-mutans-and-candida-albicans-caries-biofilm
#1
Wirginia Krzyściak, Dorota Kościelniak, Monika Papież, Palina Vyhouskaya, Katarzyna Zagórska-Świeży, Iwona Kołodziej, Beata Bystrowska, Anna Jurczak
The aim of the study was to evaluate the anti-cariogenic effects of Lactobacillus salivarius by reducing pathogenic species and biofilm mass in a double-species biofilm model. Coexistence of S. mutans with C. albicans can cause dental caries progression or recurrence of the disease in the future. Fifty-nine children with diagnosed early childhood caries (ECC) were recruited onto the study. The condition of the children's dentition was defined according to the World Health Organization guidelines. The participants were divided into children with initial enamel demineralization and children showing dentin damage...
November 14, 2017: Nutrients
https://www.readbyqxmd.com/read/29135437/an-adaptation-of-astronomical-image-processing-enables-characterization-and-functional-3d-mapping-of-individual-sites-of-excitation-contraction-coupling-in-rat-cardiac-muscle
#2
Qinghai Tian, Lars Kaestner, Laura Schröder, Jia Guo, Peter Lipp
In beating cardiomyocytes, synchronized localized Ca(2+) transients from thousands of active excitation-contraction coupling sites (ECC couplons) comprising plasma and sarcoplasmic reticulum membrane calcium channels are important determinants of the heart's performance. Nevertheless, our knowledge about their properties is limited by the lack of appropriate experimental and analysis strategies. We designed CaCLEAN to untangle fundamental characteristics of ECC couplons by combining the astronomer's CLEAN algorithm with known properties of calcium diffusion...
November 14, 2017: ELife
https://www.readbyqxmd.com/read/29133597/occupational-exposure-to-asbestos-and-risk-of-cholangiocarcinoma-a-population-based-case-control-study-in-four-nordic-countries
#3
Andrea Farioli, Kurt Straif, Giovanni Brandi, Stefania Curti, Kristina Kjaerheim, Jan Ivar Martinsen, Pär Sparen, Laufey Tryggvadottir, Elisabete Weiderpass, Guido Biasco, Francesco Saverio Violante, Stefano Mattioli, Eero Pukkala
OBJECTIVES: To assess the association between occupational exposure to asbestos and the risk of cholangiocarcinoma (CC). METHODS: We conducted a case-control study nested in the Nordic Occupational Cancer (NOCCA) cohort. We studied 1458 intrahepatic CC (ICC) and 3972 extrahepatic CC (ECC) cases occurring among subjects born in 1920 or later in Finland, Iceland, Norway and Sweden. Each case was individually matched by birth year, gender and country to five population controls...
November 13, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29125139/salivary-proteins-and-microbiota-as-biomarkers-for-early-childhood-caries-risk-assessment
#4
REVIEW
Abdullah S Hemadi, Ruijie Huang, Yuan Zhou, Jing Zou
Early childhood caries (ECC) is a term used to describe dental caries in children aged 6 years or younger. Oral streptococci, such as Streptococcus mutans and Streptococcus sorbrinus, are considered to be the main etiological agents of tooth decay in children. Other bacteria, such as Prevotella spp. and Lactobacillus spp., and fungus, that is, Candida albicans, are related to the development and progression of ECC. Biomolecules in saliva, mainly proteins, affect the survival of oral microorganisms by multiple innate defensive mechanisms, thus modulating the oral microflora...
November 10, 2017: International Journal of Oral Science
https://www.readbyqxmd.com/read/29123259/tumour-infiltrating-inflammatory-and-immune-cells-in-patients-with-extrahepatic-cholangiocarcinoma
#5
Yuki Kitano, Hirohisa Okabe, Yo-Ichi Yamashita, Shigeki Nakagawa, Yoichi Saito, Naoki Umezaki, Masayo Tsukamoto, Takanobu Yamao, Kensuke Yamamura, Kota Arima, Takayoshi Kaida, Tatsunori Miyata, Kosuke Mima, Katsunori Imai, Daisuke Hashimoto, Yoshihiro Komohara, Akira Chikamoto, Takatoshi Ishiko, Hideo Baba
BACKGROUND: Inflammation and immune characteristics of the tumour microenvironment have therapeutic significance. The aim of this study was to investigate the clinical impact on disease progression in human extrahepatic cholangiocarcinoma (ECC). METHODS: A total of 114 consecutive ECC patients with curative resection between 2000 and 2014 were enrolled. Tumour infiltrating CD66b(+) neutrophils (TANs; tumour associated neutrophils), CD163(+) M2 macrophages (TAMs; tumour associated macrophages), CD8(+) T cells, and FOXP3(+) regulatory T cells (Tregs) were assayed by immunohistochemistry, and their relationships with patient clinicopathological characteristics and prognosis were evaluated...
November 9, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/29121952/association-between-oxidative-stress-and-cord-serum-lipids-in-relation-to-delayed-cord-clamping-in-term-neonates
#6
Asmaa N Moustafa, Mahmoud H Ibrahim, Suzan Omar Mousa, Ebtesam E Hassan, Hashem F Mohamed, Hend M Moness
BACKGROUND: Although delayed cord clamping (DCC) is a recent WHO recommendation, early cord clamping (ECC) is still a routine practice in many countries. Limited researches studied the effect of delayed cord clamping on oxidative stress in term neonates; In this study we aim to assess the influence of cord clamping either early or late on oxidative stress in term neonates and to evaluate the association of oxidative stress and cord blood lipids. METHODS: One-hundred mothers and their term neonates were included in the present study...
November 9, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29118256/survey-of-knowledge-beliefs-and-behaviors-of-migrant-vietnamese-parents-regarding-young-children-s-oral-health
#7
Uyen N Nguyen, Dorothy J Rowe, Judith C Barker
Purpose: The purpose of this study was to investigate the oral health knowledge, beliefs, and behaviors of migrant Vietnamese parents of 1-5 year-olds in San Jose, California.Method: A verbally-administered survey was conducted with a convenience sample of 45 Vietnamese parents recruited at San Jose public libraries. Following preliminary screening, written informed consent was obtained from eligible individuals. A pre-tested, structured 94-item questionnaire was used to collect information regarding parent demographics, and the parent's knowledge, beliefs, and behaviors about children's oral health...
April 2017: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29118081/perceptions-of-dental-hygienists-and-dentists-about-preventing-early-childhood-caries-a-qualitative-study
#8
Alice M Horowitz, Dushanka V Kleinman, Wendy Child, Sarah D Radice, Catherine Maybury
Purpose: The objective of this qualitative pilot study was to gain an in-depth understanding of dental hygienists and dentists perspectives regarding children's oral health and what needs to be done to prevent early childhood caries (ECC), the most frequent chronic disease of childhood.Methods: A skilled facilitator conducted four focus groups and four phone interviews with 20 dental hygienists and 17 dentists practicing in a variety of locations within the state of Maryland. The interview guide was based on results from previous state-wide surveys of dental hygienists and dentists...
August 2017: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29116121/interplay-between-exciton-and-free-carriers-in-organolead-perovskite-films
#9
Wei Wang, Yu Li, Xiangyuan Wang, Yang Liu, Yanping Lv, Shufeng Wang, Kai Wang, Yantao Shi, Lixin Xiao, Zhijian Chen, Qihuang Gong
For highly interested organolead perovskite based solar cells, the exciton and free carriers are the photoproducts in the working layers. In this study, we revealed their two forms of relations depending on heat-annealing condition. In non-annealed films and single crystal, they are in density-dependent dynamical balance (co-existing). For the sufficiently heat-annealed films, they present a significant emissive exciton-carrier collision (ECC). The two relations indicate the emergence of a subgrain morphology within the tetragonal phase of crystal grain, induced by heat annealing process...
November 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29114060/ethics-rounds-death-after-pediatric-dental-anesthesia-an-avoidable-tragedy
#10
Helen Lee, Peter Milgrom, Colleen E Huebner, Philip Weinstein, Wylie Burke, Erika Blacksher, John D Lantos
Early childhood caries (ECC) is the single most common chronic childhood disease. In the treatment of ECC, children are often given moderate sedation or general anesthesia. An estimated 100 000 to 250 000 pediatric dental sedations are performed annually in the United States. The most common medications are benzodiazepines, opioids, local anesthetics, and nitrous oxide. All are associated with serious adverse events, including hypoxemia, respiratory depression, airway obstruction, and death. There is no mandated reporting of adverse events or deaths, so we don't know how often these occur...
November 7, 2017: Pediatrics
https://www.readbyqxmd.com/read/29113249/transcriptome-analysis-reveals-dysregulated-long-non-coding-rnas-and-mrnas-associated-with-extrahepatic-cholangiocarcinoma-progression
#11
Fumin Zhang, Ming Wan, Yi Xu, Zhenglong Li, Pengcheng Kang, Xingming Jiang, Yimin Wang, Zhidong Wang, Xiangyu Zhong, Chunlong Li, Yunfu Cui
The incidence of extrahepatic cholangiocarcinoma (ECC) is the highest of all the cholangiocarcinoma cases. However, the molecular mechanism of ECC genesis and progression remains unclear. Long non-coding RNAs (lncRNAs) have been revealed to perform critical regulatory roles in cancer biology. In order to understand lncRNA expression patterns and their potential function in ECC, a transcriptome analysis of lncRNA and mRNA expression was performed in ECC and paired adjacent non-cancerous tissues using Agilent human lncRNA + mRNA arrayV4...
November 2017: Oncology Letters
https://www.readbyqxmd.com/read/29112672/diagnosis-of-cervical-precancers-by-endocervical-curettage-at-colposcopy-of-women-with-abnormal-cervical-cytology
#12
Angela Hui-Chia Liu, Joan Walker, Julia C Gage, Michael A Gold, Rosemary Zuna, S Terence Dunn, Mark Schiffman, Nicolas Wentzensen
OBJECTIVE: To evaluate the performance of routine endocervical curettage (ECC) for diagnosing high-grade cervical intraepithelial neoplasia (CIN) 2 or worse and additional precancers not otherwise detected by ectocervical biopsies. METHODS: In a secondary analysis of the Biopsy Study, a cross-sectional study conducted between 2009 and 2012 at the University of Oklahoma Health and Sciences Center that found an incremental increase in detection of cervical precancers by multiple biopsies at colposcopy, ECC was performed in most women aged 30 years or older...
November 3, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29107949/user-perception-of-endocervical-sampling-a-randomized-comparison-of-endocervical-evaluation-with-the-curette-vs-cytobrush
#13
Manuela Undurraga, Rosa Catarino, Isabelle Navarria, Yasmine Ibrahim, Evelyne Puget, Isabelle Royannez Drevard, Jean-Claude Pache, Jean-Christophe Tille, Patrick Petignat
OBJECTIVES: To evaluate whether the endocervical brush (ECB) is better accepted by patients and health care providers for endocervical evaluation when compared to the endocervical curette (ECC), without a decrease in the quality of sampling. METHODS: Two hundred patients with cervical dysplasia were randomized at the colposcopy clinic of the University Hospital of Geneva into two groups according to technique. Patients and physicians' preference regarding the technique as well as the quality of samples were assessed...
2017: PloS One
https://www.readbyqxmd.com/read/29106407/highly-accurate-fluorogenic-dna-sequencing-with-information-theory-based-error-correction
#14
Zitian Chen, Wenxiong Zhou, Shuo Qiao, Li Kang, Haifeng Duan, X Sunney Xie, Yanyi Huang
Eliminating errors in next-generation DNA sequencing has proved challenging. Here we present error-correction code (ECC) sequencing, a method to greatly improve sequencing accuracy by combining fluorogenic sequencing-by-synthesis (SBS) with an information theory-based error-correction algorithm. ECC embeds redundancy in sequencing reads by creating three orthogonal degenerate sequences, generated by alternate dual-base reactions. This is similar to encoding and decoding strategies that have proved effective in detecting and correcting errors in information communication and storage...
November 6, 2017: Nature Biotechnology
https://www.readbyqxmd.com/read/29106352/the-oral-health-of-preschool-children-of-refugee-and-immigrant-families-in-manitoba
#15
Mohamed El Azrak, Alice Huang, Khalida Hai-Santiago, Mary F Bertone, Daniella DeMaré, Robert J Schroth
INTRODUCTION: Children of newcomers to Canada have been identified as at moderately high risk for developing early childhood caries (ECC). The purpose of this study was to investigate the oral health of preschool children of refugee and immigrant families in Winnipeg. METHODS: Children < 72 months of age and their parent or primary caregiver were recruited through several newcomer settlement agencies, dental clinics and community programs. Parents and caregivers completed a short questionnaire with the assistance of a research team member...
January 2017: Journal—Canadian Dental Association, Journal de L'Association Dentaire Canadienne
https://www.readbyqxmd.com/read/29104381/comparison-of-antimicrobial-efficacy-of-green-tea-garlic-with-lime-and-sodium-fluoride-mouth-rinses-against-streptococcus-mutans-lactobacilli-species-and-candida-albicans-in-children-a-randomized-double-blind-controlled-clinical-trial
#16
Ann Thomas, Sneha Thakur, Rishika Habib
Introduction: With greater awareness worldwide, the use of herbs and herbal products has increased to a large extent. Objective: To evaluate and compare the antimicrobial efficacy of green tea, garlic with lime, and 0.05% sodium fluoride (NaF) mouth rinses against Streptococcus mutans, Lactobacilli species, and Candida albicans. Materials and methods: A total of 45 children aged 4 to 6 years with severe early childhood caries (S-ECC; based on decayed extracted filled [defs] score) were selected...
July 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29101631/effect-of-placental-transfusion-on-iron-stores-in-moderately-preterm-neonates-of-30-33%C3%A2-weeks-gestation
#17
Bikramjit Das, Venkataseshan Sundaram, Praveen Kumar, William T Mordi, Lakhbir K Dhaliwal, Reena Das
OBJECTIVE: To assess the effect of placental transfusion by delayed cord clamping (DCC) of 60 s or cord milking (CM) on serum ferritin levels at hospital discharge and 3 mo of postmenstrual age (PMA) in preterm neonates of 30 to 33 wk gestation in comparison to early cord clamping (ECC) within 10 s. METHODS: This mixed longitudinal study was conducted in moderately preterm neonates of 30 to 33 wk gestation born in a level III unit in Northern India with the study sample nested within a randomized controlled trial on placental transfusion...
November 4, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29100062/thoracic-extra-coronary-calcification-for-the-prediction-of-stroke-the%C3%A2-multi-ethnic-study-of-atherosclerosis
#18
Sina Kianoush, Mahmoud Al Rifai, Miguel Cainzos-Achirica, Mouaz H Al-Mallah, Geoffrey H Tison, Joseph Yeboah, Michael D Miedema, Matthew A Allison, Nathan D Wong, Andrew P DeFilippis, William Longstreth, Khurram Nasir, Matthew J Budoff, Kunihiro Matsushita, Michael J Blaha
BACKGROUND AND AIMS: Atherosclerosis is a systemic disease. We examined whether the cumulative burden of thoracic extra-coronary calcification (ECC) improves prediction of stroke, transient ischemic attack (TIA), and stroke mortality beyond traditional risk factors and coronary artery calcium (CAC). METHODS: We followed a total of 6805 participants (mean age 62.1 ± 10.2 years, 47.2% male) from the Multi-Ethnic Study of Atherosclerosis (MESA) over a median of 12...
October 7, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29098540/multiscale-persistent-functions-for-biomolecular-structure-characterization
#19
Kelin Xia, Zhiming Li, Lin Mu
In this paper, we introduce multiscale persistent functions for biomolecular structure characterization. The essential idea is to combine our multiscale rigidity functions (MRFs) with persistent homology analysis, so as to construct a series of multiscale persistent functions, particularly multiscale persistent entropies, for structure characterization. To clarify the fundamental idea of our method, the multiscale persistent entropy (MPE) model is discussed in great detail. Mathematically, unlike the previous persistent entropy (Chintakunta et al...
November 2, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/29091788/trying-to-bridge-the-worlds-of-home-visitation-and-child-welfare-lessons-learned-from-a-formative-evaluation
#20
Mary Jo Stahlschmidt, Melissa Jonson-Reid, Laura Pons, John Constantino, Patricia L Kohl, Brett Drake, Wendy Auslander
Young children in families contacting the child welfare system are at high risk of recurrent maltreatment and poor developmental outcomes. Home visitation programs to support parenting may offer hope as a preventive resource but these programs are rarely linked with child welfare. This article describes findings from a formative evaluation of a program designed to connect child welfare-involved families to an existing evidence-supported home visitation program. The program, Early Childhood Connections (ECC), was developed by a field-university partnership including leaders from a public state child welfare system, regional early childhood education systems, and several local agencies providing family support services...
October 5, 2017: Evaluation and Program Planning
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