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https://www.readbyqxmd.com/read/28546927/safety-of-hydroimplantation-in-cataract-surgery-in-patients-with-pseudoexfoliation-syndrome
#1
Tevfik Oğurel, Reyhan Oğurel, Zafer Onaran, Kemal Örnek
AIM: To evaluate the safety of hydroimplantation in cataract surgery in patients with pseudoexfoliation syndrome. METHODS: This prospective randomized study comprised 100 eyes of 100 consecutive patients who underwent cataract surgery and implantation of foldable intraocular lens (IOL). Each eye was assigned to group 1 or group 2. Hydroimplantation without using viscoelastic agent as group 1 (n=50), and hydroxypropylmethylcellulose (Eyevisc, Biotech, India) was used in group 2 (n=50)...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28545820/extracardiac-conduit-fontan-outcome-data-in-early-adulthood
#2
Dominica Zentner, Caitlin Cheshire, Leeanne Grigg
BACKGROUND: To describe the survival and health outcome status of young adults with an extracardiac Fontan procedure performed either as a primary or conversion (secondary) Fontan surgery. METHODS: The database of the Adult Congenital Heart disease service at the Royal Melbourne Hospital was interrogated to identify all adults who had undergone a primary extracardiac conduit Fontan (n=29) or a Fontan conversion with this procedure (n=8). We then determined vital status, age, original anatomy and functional status in early adulthood in both groups...
May 3, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28542636/influence-of-learning-styles-on-the-practical-performance-after-the-four-step-basic-life-support-training-approach-an-observational-cohort-study
#3
Hanna Schröder, Alexandra Henke, Lina Stieger, Stefan Beckers, Henning Biermann, Rolf Rossaint, Saša Sopka
BACKGROUND: Learning and training basic life support (BLS)-especially external chest compressions (ECC) within the BLS-algorithm-are essential resuscitation training for laypersons as well as for health care professionals. The objective of this study was to evaluate the influence of learning styles on the performance of BLS and to identify whether all types of learners are sufficiently addressed by Peyton's four-step approach for BLS training. METHODS: A study group of first-year medical students (n = 334) without previous medical knowledge was categorized according to learning styles using the German Lernstilinventar questionnaire based on Kolb's Learning Styles Inventory...
2017: PloS One
https://www.readbyqxmd.com/read/28538317/effects-of-inertial-setting-on-power-force-work-and-eccentric-overload-during-flywheel-resistance-exercise-in-women-and-men
#4
Luis M Martinez-Aranda, Rodrigo Fernandez-Gonzalo
Martinez-Aranda, LM and Fernandez-Gonzalo, R. Effects of inertial setting on power, force, work and eccentric overload during flywheel resistance exercise in women and men. J Strength Cond Res 31(6): 1653-1661, 2017-Exercise load is a key component in determining end-point adaptations to resistance exercise. Yet, there is no information regarding the use of different inertia (i.e., loads) during isoinertial flywheel resistance exercise, a very popular high-intensity training model. Thus, this study examined power, work, force, and eccentric overload produced during flywheel resistance exercise with different inertial settings in men and women...
June 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28538220/identification-of-caries-risk-determinants-in-toddlers-results-of-the-gusto-birth-cohort-study
#5
C Un Lam, L W Khin, A C Kalhan, R Yee, Y S Lee, M F-F Chong, K Kwek, S M Saw, K Godfrey, Y S Chong, C-Y Hsu
The aim of this study was to identify risk determinants leading to early childhood caries (ECC) and visible plaque (VP) in toddlers. Data for mother-child pairs participating in the Growing Up in Singapore towards Healthy Outcomes (GUSTO) birth cohort were collected from pregnancy to toddlerhood. Oral examinations were performed in 543 children during their clinic visit at 24 months to detect ECC and VP. Following logistic regression, ECC and VP were jointly regressed as primary and secondary outcomes, respectively, using the bivariate probit model...
May 25, 2017: Caries Research
https://www.readbyqxmd.com/read/28535665/l1-cell-adhesion-molecule-promotes-migration-and-invasion-via-jnk-activation-in-extrahepatic-cholangiocarcinoma-cells-with-activating-kras-mutation
#6
Haejung Kim, Haein Hwang, Hansoo Lee, Hyo Jeong Hong
Extrahepatic cholangiocarcinoma (ECC), a malignant tumor of biliary origin, has a poor prognosis with limited treatment options. The KRAS oncogene is the most commonly mutated gene in ECC and one of the factors that predicts a poor prognosis and low survival rate. L1 cell adhesion molecule (L1CAM) is expressed in ECC cells and acts as an independent poor prognostic factor in predicting patient survival. In this study we investigate the functional significance of L1CAM in ECC cells with activating KRAS mutation...
May 24, 2017: Molecules and Cells
https://www.readbyqxmd.com/read/28526003/the-basic-research-factors-questionnaire-for-studying-early-childhood-caries
#7
Judith Albino, Tamanna Tiwari, Stuart A Gansky, Michelle M Henshaw, Judith C Barker, Angela G Brega, Steven E Gregorich, Brenda Heaton, Terrence S Batliner, Belinda Borrelli, Paul Geltman, Nancy R Kressin, Jane A Weintraub, Tracy L Finlayson, Raul I Garcia
BACKGROUND: We describe development of the Early Childhood Caries (ECC) Basic Research Factors Questionnaire (BRFQ), a battery of measures assessing common potential predictors, mediators, and moderators of ECC. Individual-, family-, and community-level factors that are linked to oral health outcomes across at-risk populations are included. Developing standard measures of factors implicated in ECC has the potential to enhance our ability to understand mechanisms underlying successful prevention and to develop more effective interventions...
May 19, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28514517/early-childhood-caries-and-psychological-perceptions-on-child-s-oral-health-increase-the-feeling-of-guilt-in-parents-an-epidemiological-survey
#8
Thiago Saads Carvalho, Jenny Abanto, Elayne Cristina Morais Pinheiro, Adrian Lussi, Marcelo Bönecker
AIM: To assess whether parents feel guilty for their children's oral problems, associating this feeling with socio-economic, demographic, and psychological factors. DESIGN: We included 1313 parent-and-child pairs in this study. The children were 2-4 years old. Parents answered questionnaires on socio-economic and demographic data, and on psychological variables. Sixteen trained dentists (κ > 0.8) examined the children for oral hygiene (the presence and absence of plaque), early childhood caries (ECC; no caries, low and high severity), malocclusion (the presence and absence), and traumatic dental injuries (TDI; the presence and absence)...
May 17, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/28505628/markers-of-intestinal-damage-and-their-relation-to-cytokine-levels-in-cardiac-surgery-patients
#9
Quirine L M Habes, Vera Linssen, Suzan Nooijen, Dorien Kiers, Jelle Gerretsen, Peter Pickkers, Gert Jan Scheffer, Matthijs Kox
OBJECTIVES: In patients undergoing cardiac surgery, both extracorporeal circulation (ECC) and intraoperative mesenterial hypoperfusion may account for increased cytokine levels and lead to postoperative gastrointestinal (GI) symptoms. METHODS: We investigated levels of the intestinal damage markers intestinal fatty acid binding protein (I-FABP in plasma [n = 72] and urine [n = 37]), citrulline (in plasma [n = 35]), and claudin-3 (in urine [n = 37]) in patients undergoing aortic or mitral valve surgery with or without coronary artery bypass grafting...
June 2017: Shock
https://www.readbyqxmd.com/read/28492756/a-longitudinal-study-of-early-childhood-caries-and-associated-factors-in-brazilian-children
#10
Fabiane Piva, Joanna Tatith Pereira, Patrícia Blaya Luz, Lina Naomi Hashizume, Fernando Neves Hugo, Fernando Borba de Araujo
Early childhood caries (ECC) affects children all over the world and has high prevalence and severity in preschool children. Different social, biological and behavioral factors compose a network of causal factors for ECC. The aim was to evaluate the association between socioeconomic variables and caries at baseline, and the presence of Streptococcus mutans and Lactobacillus spp. microorganisms with the progression of caries lesions after two years of follow-up in a group of children. At baseline, 163 children (3-4 years old) living in the areas of 12 primary care services of the Hospital Group Conceição (GHC, Porto Alegre, RS, Brazil) were evaluated...
March 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/28492198/comparison-of-efficacy-of-three-chemotherapeutic-agents-on-streptococcus-mutans-count-in-plaque-and-saliva-a-randomized-controlled-triple-blind-study
#11
Ajay Narayan, Savitha Satyaprasad, S Anandraj, S R Ananda, P Ananth Kamath, S Nandan
BACKGROUND: There is a need for exploration of the role of chemotherapeutic agents and its role in the prevention of early childhood caries (ECC) and its recurrence. AIM: The aim of this study was two-fold: (1) To compare the antimicrobial efficacy of three commonly used chemotherapeutic agents in the prevention of ECC in comparison with a control and (2) To ascertain the role of chemotherapeutic agents in the prevention of ECC. MATERIALS AND METHODS: Sixty children with ECC in the age group 3-6 years were randomly allocated into four groups...
April 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28489792/eye-bank-prepared-versus-surgeon-cut-endothelial-graft-tissue-for-descemet-membrane-endothelial-keratoplasty-an-observational-study
#12
Marie Regnier, Céline Auxenfans, Delphine Maucort-Boulch, Anne-Sophie Marty, Odile Damour, Carole Burillon, Viridiana Kocaba
The purpose of this article is to examine outcomes of Descemet membrane endothelial keratoplasty (DMEK) performed with cornea bank (CB) prestripped tissue and surgeon stripped tissue (SST).This retrospective study examined subjects who underwent DMEK with CB or surgeon prepared tissue for Fuchs endothelial corneal dystrophy. Best-corrected visual acuity (BCVA), corneal thickness, endothelial cell count (ECC), and complications were examined before and throughout a 6-month postoperative period.Eleven CB and 22 SST subjects were included...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28481037/regional-quantification-of-myocardial-mechanics-in-rat-using-3d-cine-dense-cardiovascular-magnetic-resonance
#13
Xiaoyan Zhang, Zhan-Qiu Liu, Dara Singh, Gregory J Wehner, David K Powell, Kenneth S Campbell, Brandon K Fornwalt, Jonathan F Wenk
Rat models have assumed an increasingly important role in cardiac research. However, a detailed profile of regional cardiac mechanics, such as strains and torsion, is lacking for rats. We hypothesized that healthy rat left ventricles (LVs) exhibit regional differences in cardiac mechanics, which are part of normal function. In this study, images of the LV were obtained with 3D cine displacement encoding with stimulated echoes (DENSE) cardiovascular magnetic resonance in 10 healthy rats. To evaluate regional cardiac mechanics, the LV was divided into basal, mid-ventricular, and apical regions...
May 8, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28472136/the-efficacy-of-the-cyclin-dependent-kinase-4-6-inhibitor-in-endometrial-cancer
#14
Tomohito Tanaka, Yoshito Terai, Keisuke Ashihara, Satoe Fujiwara, Yoshimichi Tanaka, Hiroshi Sasaki, Satoshi Tsunetoh, Masahide Ohmichi
BACKGROUND: PD-0332991, the selective cyclin-dependent kinase 4/6 inhibitor palbociclib, causes cell cycle arrest by inhibiting phosphorylation of retinoblastoma (Rb) protein. The aim of this study was to evaluate the therapeutic potential of PD-0332991 in endometrial cancer. METHODS AND FINDINGS: Four human endometrial cancer cell lines, ECC, HEC1A, HEC108 and TEN, were treated with PD-0332991 and their function was evaluated. In vivo, the therapeutic efficacy was evaluated in a model of subcutaneous endometrial cancer...
2017: PloS One
https://www.readbyqxmd.com/read/28456828/resource-utilization-associated-with-extracardiac-co-morbid-conditions-following-congenital-heart-surgery-in-infancy
#15
Krista E Tuomela, John B Gordon, Laura D Cassidy, Sarah Johaningsmeir, Nancy S Ghanayem
Congenital heart disease (CHD) is often associated with chronic extracardiac co-morbid conditions (ECC). The presence of ECC has been associated with greater resource utilization during the operative period; however, the impact beyond hospital discharge has not been described. This study sought to understand the scope of chronic ECC in infants with CHD as well as to describe the impact of ECC on resource utilization after discharge from the index cardiac procedure. IRB approved this retrospective study of infants <1 year who had cardiac surgery from 2006 and 2011...
April 29, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28449321/a-review-of-associated-controversies-surrounding-glucocorticoid-use-in-veterinary-emergency-and-critical-care
#16
Maya A Aharon, Jennifer E Prittie, Kate Buriko
OBJECTIVE: To review the literature in human and veterinary medicine regarding the indications for, efficacy of, and controversies surrounding glucocorticoid (GC) administration in the emergency and critical care (ECC) setting, and to provide an overview of the most commonly used synthetic GC formulations. MEDICATIONS: Synthetic GCs vary in GC and mineralocorticoid potency, hypothalamic pituitary axis suppression, duration of action, route of administration, and clinical indication for use...
May 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/28449292/oral-health-beliefs-knowledge-and-behaviors-in-northern-california-american-indian-and-alaska-native-mothers-regarding-early-childhood-caries
#17
Brenda Heaton, Andrew Crawford, Raul I Garcia, Michelle Henshaw, Christine A Riedy, Judith C Barker, Maureen A Wimsatt
OBJECTIVES: To assess the oral health beliefs, knowledge, and behaviors related to early childhood caries (ECC) risk in a convenience sample of American Indian and Alaska Native (AIAN) mothers residing in rural Northern California communities. METHODS: Fifty-three mothers of young children were recruited from three tribal communities in Northern California with the assistance of the California Rural Indian Health Board, Inc. and its California Tribal Epidemiology Center and Dental Support Center...
April 27, 2017: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/28445270/pooled-analysis-on-the-necessity-of-random-4-quadrant-cervical-biopsies-and-endocervical-curettage-in-women-with-positive-screening-but-negative-colposcopy
#18
Shang-Ying Hu, Wen-Hua Zhang, Shu-Min Li, Nan Li, Man-Ni Huang, Qin-Jing Pan, Xun Zhang, Ying Han, Fang-Hui Zhao, Wen Chen, You-Lin Qiao
Controversy remains over whether random cervical biopsies and endocervical curettage (ECC) should be used in women with positive screening but negative colposcopy. Our paper aims to determine the indications for random biopsies and ECC among these screened positive women.Three thousand two hundred thirteen women with any positive screening test result but negative colposcopy, who received random 4-quadrant biopsies, were pooled from 17 population-based cervical cancer screening studies done in China from 1999 to 2008...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28444936/blood-flow-restriction-attenuates-eccentric-exercise-induced-muscle-damage-without-perceptual-and-cardiovascular-overload
#19
Victor M Curty, Alexandre B Melo, Leonardo C Caldas, Lucas Guimarães-Ferreira, Nuno F de Sousa, Paula F Vassallo, Elisardo C Vasquez, Valério G Barauna
The aim of this study was to evaluate the acute effects of high-intensity eccentric exercise (HI-ECC) combined with blood flow restriction (BFR) on muscle damage markers, and perceptual and cardiovascular responses. Nine healthy men (26 ± 1 years, BMI 24 ± 1 kg m(-) ²) underwent unilateral elbow extension in two conditions: without (HI-ECC) and with BFR (HI-ECC+BFR). The HI-ECC protocol corresponded to three sets of 10 repetitions with 130% of maximal strength (1RM). The ratings of perceived exertion (RPE) and pain (RPP) were measured after each set...
April 26, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28439013/biliary-epithelial-injury-induced-regenerative-response-by-il-33-promotes-cholangiocarcinogenesis-from-peribiliary-glands
#20
Hayato Nakagawa, Nobumi Suzuki, Yoshihiro Hirata, Yohko Hikiba, Yoku Hayakawa, Hiroto Kinoshita, Sozaburo Ihara, Koji Uchino, Yuji Nishikawa, Hideaki Ijichi, Motoyuki Otsuka, Junichi Arita, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo, Keisuke Tateishi, Kazuhiko Koike
The carcinogenic mechanism of extrahepatic cholangiocarcinoma (ECC) is unclear, due at least in part to the lack of an appropriate mouse model. Because human studies have reported frequent genetic alterations in the Ras- and TGFβ/SMAD-signaling pathways in ECC, mice with tamoxifen-inducible, duct-cell-specific Kras activation and a TGFβ receptor type 2 (TGFβR2) deletion were first generated by crossing LSL-Kras(G12D) , Tgfbr2(flox/flox) , and K19(CreERT) mice (KT-K19(CreERT) ). However, KT-K19(CreERT) mice showed only mild hyperplasia of biliary epithelial cells (BECs) in the extrahepatic bile duct (EHBD) and died within 7 wk, probably a result of lung adenocarcinomas...
May 9, 2017: Proceedings of the National Academy of Sciences of the United States of America
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