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https://www.readbyqxmd.com/read/28731879/peripheral-endothelial-cell-count-is-a-predictor-of-disease-severity-in-advanced-fuchs-endothelial-corneal-dystrophy
#1
Zeba A Syed, Jennifer A Tran, Ula V Jurkunas
PURPOSE: In advanced Fuchs endothelial corneal dystrophy (FECD), central endothelial changes do not correlate with disease severity. The peripheral endothelial cell count (ECC) has not been studied as a marker of FECD severity. The goal of this study was to determine the relationship between the peripheral ECC and known clinical markers of FECD in advanced cases. METHODS: Patients with FECD examined between January 1, 2013, and September 1, 2016, by 1 cornea specialist were identified...
July 19, 2017: Cornea
https://www.readbyqxmd.com/read/28725197/skeletal-muscle-remodeling-in-response-to-eccentric-vs-concentric-loading-morphological-molecular-and-metabolic-adaptations
#2
REVIEW
Martino V Franchi, Neil D Reeves, Marco V Narici
Skeletal muscle contracts either by shortening or lengthening (concentrically or eccentrically, respectively); however, the two contractions substantially differ from one another in terms of mechanisms of force generation, maximum force production and energy cost. It is generally known that eccentric actions generate greater force than isometric and concentric contractions and at a lower metabolic cost. Hence, by virtue of the greater mechanical loading involved in active lengthening, eccentric resistance training (ECC RT) is assumed to produce greater hypertrophy than concentric resistance training (CON RT)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28721668/quantitative-analysis-of-s-mutans-lactobacillus-and-bifidobacterium-found-in-initial-and-mature-plaques-in-thai-children-with-early-childhood-caries
#3
K Mitrakul, S Chanvitan, A Jeamset, K Vongsawan
AIMS: To quantify Streptococcus mutans, lactobacillus and bifidobacterium in initial and mature plaque collected from children with severe early childhood caries (S-ECC) and caries-free (CF) groups and to analyse the association between these bacteria and caries-related factors in each group. STUDY DESIGN: A collection of 120 initial and overnight supra-gingival plaques were collected from Thai children aged 2-5 years-old (S-ECC = 60, CF = 60). Plaque, gingival indices and decayed, missing, filled tooth (dmft) scores were recorded...
July 18, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28719748/low-temperature-fusible-silver-micro-nano-dendrites-based-electrically-conductive-composites-for-next-generation-printed-fuse-links
#4
Rui Yang, Yang Wang, Dang Wu, Yubin Deng, Yingying Luo, Xiaoya Cui, Xuanyu Wang, Zhixue Shu, Cheng Yang
We systematically investigate the long-neglected low-temperature fusing behavior of silver micro/nano-dendrites and demonstrate the feasibility of employing this intriguing property for the printed electronics application, i.e. printed fuse-link. Fuse-link has experienced insignificant changes since they were invented in 1890's. By introducing the silver micro/nano-dendrites based electrically conductive composites (ECCs) as the printed fusible element, coupled with the state-of-the-art printed electronics technology, key performance characteristics of a fuse-link are dramatically improved as compared with the commercially-available counterparts, including expedient fabrication process, lower-available rated current (40% of the minimum value of Littelfuse 467 series fuses), shorter response time (only 3...
July 18, 2017: ACS Nano
https://www.readbyqxmd.com/read/28718916/the-genetic-landscape-of-endometrial-clear-cell-carcinomas
#5
Deborah F DeLair, Kathleen A Burke, Pier Selenica, Raymond S Lim, Sasinya N Scott, Sumit Middha, Abhinita S Mohanty, Donavan T Cheng, Michael F Berger, Robert A Soslow, Britta Weigelt
Clear cell carcinoma of the endometrium is a rare type of endometrial cancer generally associated with an aggressive clinical behavior. Here we sought to define the repertoire of somatic genetic alterations in endometrial clear cell carcinomas (ECCs) and whether ECCs could be classified into the molecular subtypes described for endometrial endometrioid and serous carcinomas. We performed a rigorous histopathological review, immunohistochemical analysis and massively parallel sequencing targeting 300 cancer-related genes of 32 pure ECCs...
July 18, 2017: Journal of Pathology
https://www.readbyqxmd.com/read/28717347/effect-of-eicosapentaenoic-acids-rich-fish-oil-supplementation-on-motor-nerve-function-after-eccentric-contractions
#6
Eisuke Ochi, Yosuke Tsuchiya, Kenichi Yanagimoto
BACKGROUND: This study investigated the effect of supplementation with fish oil rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the M-wave latency of biceps brachii and muscle damage after a single session of maximal elbow flexor eccentric contractions (ECC). METHODS: Twenty-one men were completed the randomized, double-blind, placebo-controlled, and parallel-design study. The subjects were randomly assigned to the fish oil group (n = 10) or control group (n = 11)...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28715734/simultaneous-algae-polluted-water-treatment-and-electricity-generation-using-a-biocathode-coupled-electrocoagulation-cell-bio-ecc
#7
Yue Dong, Youpeng Qu, Chao Li, Xiaoyu Han, John J Ambuchi, Junfeng Liu, Yanling Yu, Yujie Feng
How to utilize electrocoagulation (EC) technology for algae-polluted water treatment in an energy-efficient manner remains a critical challenge for its widespread application. Herein, a novel biocathode-coupled electrocoagulation cell (bio-ECC) with sacrificial iron anode and nitrifying biocathode was developed. Under different solution conductivities (2.33±0.25mScm(-1) and 4.94±0.55mScm(-1)), the bio-ECC achieved almost complete removal of algae cells. The maximum power densities of 8.41 and 11.33Wm(-3) at corresponding current densities of 48...
June 23, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28713800/strategies-for-meaningful-engagement-between-community-based-health-researchers-and-first-nations-participants
#8
Jaime Cidro, Marion Maar, Sabrina Peressini, Robert J Schroth, John Broughton, Lisa Jamieson, Herenia P Lawrence
The Baby Teeth Talk Study (BTT) is a partnership-based research project looking at interventions to prevent early childhood caries (ECC) in First Nations populations in Canada. Community-based researchers (CBRs) conducted preventive and behavioral interventions that targeted expectant mothers and their newborns, over a 3-year period. The work of the CBRs requires a great deal of training and skills to administer the interventions. It also requires a broad set of strategies to meaningfully engage participants to make health-promoting changes in their behavior to prevent ECC in their children...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28709424/genotypic-diversity-and-phenotypic-traits-of-streptococcus-mutans-isolates-and-their-relation-to-severity-of-early-childhood-caries
#9
Remberto Marcelo Argandoña Valdez, Cristiane Duque, Karina Sampaio Caiaffa, Vanessa Rodrigues Dos Santos, Maria Luiza de Aguiar Loesch, Natalia Helena Colombo, Rodrigo Alex Arthur, Thais de Cássia Negrini, Marcelo Fabiano Gomes Boriollo, Alberto Carlos Botazzo Delbem
BACKGROUND: Early childhood caries (ECC) is an aggressive condition that can affect teeth of young children. This study aimed to evaluate genotypic diversity and phenotypic traits of S. mutans isolated from dental biofilms of children with different caries status in comparison with caries free (CF) children. METHODS: Streptococcus mutans strains were isolated from supragingival biofilm samples of CF, ECC and severe-ECC (S-ECC) children and genotyped by arbitrary-primer polymerase chain reaction - AP-PCR...
July 14, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28709393/microbiome-associated-with-severe-caries-in-canadian-first-nations-children
#10
M Agnello, J Marques, L Cen, B Mittermuller, A Huang, N Chaichanasakul Tran, W Shi, X He, R J Schroth
Young Indigenous children in North America suffer from a higher degree of severe early childhood caries (S-ECC) than the general population, leading to speculation that the etiology and characteristics of the disease may be distinct in this population. To address this knowledge gap, we conducted the first microbiome analysis of an Indigenous population using modern molecular techniques. We investigated the caries-associated microbiome among Canadian First Nations children with S-ECC. Thirty First Nations children <72 mo of age with S-ECC and 20 caries-free children were recruited in Winnipeg, Canada...
July 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28705197/genetic-polymorphism-of-scra-gene-of-streptococcus-mutans-isolates-is-not-associated-with-biofilm-formation-in-severe-early-childhood-caries
#11
Yan Zhou, Lixia Yu, Ye Tao, Qinghui Zhi, Huancai Lin
BACKGROUND: To explore and analyse the association between biofilm and the genetic polymorphisms of scrA gene of EnzymeIIscr found in clinical isolates of Streptococcus mutans (S. mutans) from severe early childhood caries (S-ECC) in 3 years old children. METHODS: Clinical strains of S. mutans were conserved from a previous study. Thirty strains of S. mutans from the S-ECC group and 30 strains of S. mutans from the caries free (CF) group were selected. Biomass and viability of biofilm formed by the strains were evaluated by crystal violet and alamar blue assay...
July 14, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28704309/effect-of-three-different-muscle-action-training-protocols-on-knee-strength-ratios-and-performance
#12
Cassio V Ruas, Lee E Brown, Camila D Lima, Pablo B Costa, Ronei S Pinto
Hamstring to quadriceps (H:Q) ratios are often used to assess strength imbalances. The aims of this study were to compare three different muscle action training protocols on H:Q strength balance and functional performance. Forty untrained males (age: 22.87 ± 2.28 y, mass: 70.66 ± 11.049 kg, ht: 174.29 ± 6.90 cm) performed 6 weeks of training on an isokinetic dynamometer. They were randomly assigned to one of 4 groups; concentric quadriceps and concentric hamstring (CON/CON), eccentric quadriceps and eccentric hamstring (ECC/ECC), concentric quadriceps and eccentric hamstring (CON/ECC), or no training (CNTRL)...
July 12, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28702057/role-of-fluoride-varnish-in-preventing-early-childhood-caries-a-systematic-review
#13
REVIEW
Poulami Mishra, Nusrath Fareed, Hemant Battur, Sanjeev Khanagar, Manohar A Bhat, Jagan Palaniswamy
BACKGROUND: Early childhood caries is a public health problem that continues to affect babies and preschool children worldwide. This untreated caries process results in progressive destruction of the crowns of the teeth, often accompanied by severe pain and suffering, affecting the quality of life. Fluoride varnish which is one of the most important materials to prevent ECC is easy to apply and well tolerated by children. This study aimed to evaluate the scientific evidence regardingthe role of fluoride varnish in preventing early childhood caries...
May 2017: Dental Research Journal
https://www.readbyqxmd.com/read/28693161/pd-l1-and-pd-1-expression-correlate-with-prognosis-in-extrahepatic-cholangiocarcinoma
#14
Ke Ma, Xin Wei, Danfeng Dong, Yinying Wu, Qianqian Geng, Enxiao Li
The present study aimed to investigate the clinicopathological significance of programmed cell death ligand-1 (PD-L1) and programmed cell death protein 1 (PD-1) expression in extrahepatic cholangiocarcinoma (ECC). PD-L1 and PD-1 expression was detected by immunohistochemical methods in 70 ECC formalin-fixed, paraffin-embedded tissue specimens and 50 para-carcinoma tissue specimens. The associations of PD-L1 and PD-1 expression with clinicopathological characteristics and prognosis of ECC patients were explored...
July 2017: Oncology Letters
https://www.readbyqxmd.com/read/28680370/effects-of-a-combined-protein-and-antioxidant-supplement-on-recovery-of-muscle-function-and-soreness-following-eccentric-exercise
#15
Stephen J Ives, Samuel Bloom, Alexs Matias, Noelle Morrow, Natalya Martins, Yookee Roh, Daniel Ebenstein, Gabriel O'Brien, Daniela Escudero, Kevin Brito, Leah Glickman, Scott Connelly, Paul J Arciero
BACKGROUND: An acute bout of eccentric contractions (ECC) cause muscle fiber damage, inflammation, impaired muscle function (MF) and muscle soreness (MS). Individually, protein (PRO) and antioxidant (AO) supplementation may improve some aspects of recovery from ECC, though have yet to be combined. We sought to determine if combined PRO and AO supplementation (PRO + AO) improves MS and MF following damaging ECC over PRO alone. METHODS: Sixty sedentary college-aged males participated in a randomized, single-blind, parallel design study of peak isometric torque (PIMT), peak isokinetic torque (PIKT), thigh circumference (TC), and muscle soreness (MS) of knee extensor muscles measured at baseline, immediately after and 1, 2, 6, and 24 h after completion of 100 maximal ECC...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28676047/a-longitudinal-study-of-early-childhood-caries-incidence-in-wenzhou-preschool-children
#16
Xiping Wang, Zhiyuan Wei, Qiao Li, Liqin Mei
BACKGROUND: Early childhood caries (ECC) is a serious public health problem in China. Few studies, however, have described the incidence of ECC in China. The purpose of this study was to assess the prevalence and incidence of ECC among preschool children in Wenzhou China. METHODS: Preschool children aged 3-4 years old were surveyed and followed up when they reached 5-6 years of age in the city of Wenzhou in southeast China. The rates of dental caries were determined with prevalence, and incidence density for risk of caries of a person (IDp) and of a tooth surface (IDs)...
July 4, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28674702/do-oral-health-educational-programmes-for-expectant-mothers-prevent-early-childhood-caries-%C3%A2-a-systematic-review
#17
Jean Aishwarya Henry, Murugan S Muthu, Kavitha Swaminathan, Richard Kirubakaran
PURPOSE: To summarise the evidence for the efficacy of oral health educational programmes provided to expectant mothers for preventing Early Childhood Caries (ECC) and to determine the most effective intervention programme. MATERIALS AND METHODS: The search strategy included clinical trials in the Cochrane Oral Health Group's Trials Register, PubMed, Science Direct, Google Scholar, LILACS and ClinicalKey (up to 26 August 2013) in English. Reference lists of identified randomised controlled trials (RCTs) and review articles were also hand searched...
2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28667581/intracameral-dexamethasone-injection-as-adjuvant-therapy-in-endothelial-immune-reaction-after-penetrating-and-posterior-lamellar-keratoplasty-a-retrospective-clinical-observation
#18
Miltiadis Fiorentzis, Arne Viestenz, Anja Viestenz, Berthold Seitz
INTRODUCTION: The aim of this observational study is to evaluate the effectiveness of an adjuvant intracameral corticosteroid injection (ICI) in cases of severe endothelial immune reaction (SEIR) (anterior chamber cells and flare, retrocorneal precipitates, Descemet's folds, and corneal edema) after penetrating keratoplasty and posterior lamellar keratoplasty. METHODS: In this retrospective study, 24 subjects treated between November 2011 and September 2014 were divided into two groups...
June 30, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28663378/factors-contributing-to-lower-metabolic-demand-of-eccentric-than-concentric-cycling
#19
Luis Penailillo, Anthony John Blazevich, Kazunori Nosaka
This study compared muscle-tendon behavior, muscle oxygenation and muscle activity between eccentric and concentric cycling exercise at the same work output to investigate why metabolic demand is lower during eccentric than concentric cycling. Eleven untrained men (27.1 ± 7.0 y) performed concentric cycling (CONC) and eccentric cycling (ECC) for 10 min (60 rpm) at 65% of the maximal concentric cycling power output (191 ± 45 W) four weeks apart. During cycling, oxygen consumption (VO2), heart rate (HR), vastus lateralis (VL) tissue total hemoglobin (tHb) and oxygenation index (TOI) were recorded, and muscle-tendon behavior was assessed using ultrasonography...
June 29, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28661802/effectiveness-on-early-childhood-caries-of-an-oral-health-promotion-program-for-medical-providers
#20
Patricia A Braun, Katina Widmer-Racich, Carter Sevick, Erin J Starzyk, Katya Mauritson, Simon J Hambidge
OBJECTIVES: To assess an oral health promotion (OHP) intervention for medical providers' impact on early childhood caries (ECC). METHODS: We implemented a quasiexperimental OHP intervention in 8 federally qualified health centers that trained medical providers on ECC risk assessment, oral examination and instruction, dental referral, and fluoride varnish applications (FVAs). We measured OHP delivery by FVA count at medical visits. We measured the intervention's impact on ECC in 3 unique cohorts of children aged 3 to 4 years in 2009 (preintervention; n = 202), 2011 (midintervention; n = 420), and 2015 (≥ 4 FVAs; n = 153)...
May 2017: American Journal of Public Health
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