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https://www.readbyqxmd.com/read/28809925/salivary-peptidome-profiling-analysis-for-occurrence-of-new-carious-lesions-in-patients-with-severe-early-childhood-caries
#1
Chang Tian, Xiangyu Sun, Xiaochen Liu, Xin Huang, Feng Chen, Shuguo Zheng
This study aimed to identify differences of peptide profiles in stimulated whole saliva among children with and without occurrence of new carious lesions, and to provide a simple way for early diagnosis and prevention of the relapse of severe early childhood caries (s-ECC). Overall, 26 children aged 3-4 years were selected out from all the children in the kindergarten to be involved in the present study, among them 13 were diagnosed as s-ECC and underwent dental treatment, whilst the other 13 were matched by age and sex as control...
2017: PloS One
https://www.readbyqxmd.com/read/28809846/the-use-of-trace-eyeblink-classical-conditioning-to-assess-hippocampal-dysfunction-in-a-rat-model-of-fetal-alcohol-spectrum-disorders
#2
Tuan D Tran, Aenia Amin, Keith G Jones, Ellen M Sheffer, Lidia Ortega, Keith Dolman
Neonatal rats were administered a relatively high concentration of ethyl alcohol (11.9% v/v) during postnatal days 4-9, a time when the fetal brain undergoes rapid organizational change and is similar to accelerated brain changes that occur during the third trimester in humans. This model of fetal alcohol spectrum disorders (FASDs) produces severe brain damage, mimicking the amount and pattern of binge-drinking that occurs in some pregnant alcoholic mothers. We describe the use of trace eyeblink classical conditioning (ECC), a higher-order variant of associative learning, to assess long-term hippocampal dysfunction that is typically seen in alcohol-exposed adult offspring...
August 5, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28802297/breastfeeding-and-early-childhood-caries-a-meta-analysis-of-observational-studies
#3
Lingling Cui, Xing Li, Yalan Tian, Juntao Bao, Ling Wang, Dongmei Xu, Bing Zhao, Wenjie Li
BACKGROUND AND OBJECTIVES: The associations of breastfeeding and early childhood caries (ECC) risk have been evaluated in several epidemiological studies with conflicting results. We performed an update meta-analysis to estimate the association of feeding patterns, breastfeeding durations and ECC risk. METHODS AND STUDY DESIGN: Studies were identified through searching Pubmed, Web of Science, and Embase from January 1990 to December 2015. RESULTS: Thirty-five studies involving 73,401 participants aged 0-71 months were included...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28800116/maintaining-traditions-a-qualitative-study-of-early-childhood-caries-risk-and-protective-factors-in-an-indigenous-community
#4
Ana Levin, Karen Sokal-Gutierrez, Anita Hargrave, Elizabeth Funsch, Kristin S Hoeft
In lower middle-income economies (LMIE), the nutrition transition from traditional diets to sugary foods and beverages has contributed to widespread early childhood dental caries. This qualitative study explores perceived risk and protective factors, and overall experiences of early childhood nutrition and oral health in indigenous Ecuadorian families participating in a community-based oral health and nutrition intervention. Dental exams of 698 children age 6 months through 6 years determined each child's caries burden...
August 11, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28783550/characterization-of-the-clustered-regularly-interspaced-short-palindromic-repeats-sites-in-streptococcus-mutans-isolated-from-early-childhood-caries-patients
#5
Jing Chen, Tiancheng Li, Xuedong Zhou, Lei Cheng, Yuanyuan Huo, Jing Zou, Yuqing Li
OBJECTIVE: The aim of this study was to analyze the characteristics of the clustered regularly interspaced short palindromic repeats (CRISPR) sites in 45 clinical Streptococcus mutans strains and their relationship to the clinical manifestations of early childhood caries (ECC). METHODS: Forty-five S. mutans strains were isolated from the plaque samples taken from sixty-three children. CRISPR sites were sequenced and BLAST was used to compare these sites to those in the CRISPRTarget database...
July 29, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28770188/early-childhood-caries-prevalence-risk-factors-and-prevention
#6
REVIEW
Sukumaran Anil, Pradeep S Anand
Early childhood caries (ECC) is major oral health problem, mainly in socially disadvantaged populations. ECC affects infants and preschool children worldwide. The prevalence of ECC differs according to the group examined, and a prevalence of up to 85% has been reported for disadvantaged groups. ECC is the presence of one or more decayed, missing, or filled primary teeth in children aged 71 months (5 years) or younger. It begins with white-spot lesions in the upper primary incisors along the margin of the gingiva...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28768216/a-multi-omics-based-ecological-analysis-of-coastal-marine-sediments-from-gladstone-in-australia-s-central-queensland-and-heron-island-a-nearby-fringing-platform-reef
#7
D J Beale, J Crosswell, A V Karpe, W Ahmed, M Williams, P D Morrison, S Metcalfe, C Staley, M J Sadowsky, E A Palombo, A D L Steven
The impact of anthropogenic factors arising from point and non-point pollution sources at a multi commodity marine port and its surrounding ecosystems were studied using sediment samples collected from a number of onshore (Gladstone Harbour and Facing Island) and offshore (Heron Island and Fitzroy Reefs) sites in Australia's Central Queensland. Sediment samples were analyzed for trace metals, organic carbon, polycyclic aromatic hydrocarbons (PAH), emerging chemicals of concern (ECC) and sterols. Similarly, the biological and biochemical interaction between the reef and its environment was analyzed by the multi-omic tools of next-generation sequencing characterization of the bacterial community and microbial community metabolic profiling...
July 30, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28764894/investigating-empathy-in-interpreter-mediated-simulated-consultations-an-explorative-study
#8
Demi Krystallidou, Aline Remael, Esther de Boe, Kristin Hendrickx, Giannoula Tsakitzidis, Sofie van de Geuchte, Peter Pype
OBJECTIVE: To explore i) the ways in which empathic communication is expressed in interpreter-mediated consultations; ii) the interpreter's effect on the expression of empathic communication. METHODS: We coded 9 video-recorded interpreter-mediated simulated consultations by using the Empathic Communication Coding System (ECCS) which we used for each interaction during interpreter-mediated consultations. We compared patients' empathic opportunities and doctors' responses as expressed by the patients and doctors and as rendered by the interpreters...
July 23, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28762633/platelet-activation-and-clotting-cascade-activation-by-dialyzers-designed-for-high-volume-online-hemodiafiltration
#9
Kamonwan Tangvoraphonkchai, Anne Riddell, Andrew Davenport
INTRODUCTION: Hemodialysis patients are pro-thrombotic. Higher volume online postdilutional hemodiafiltration (OL-HDF), with increasing hematocrit increases the risk of clotting in the extracorporeal circuit (ECC). We wished to determine whether OL-HDF increased platelet activation and ECC clotting. METHODS: Coagulation parameters, platelet, white cell, and endothelial activation markers were measured at the start and end of dialysis sessions in 10 patients and also pre- and post-dialyzer after 15 minutes using two different dialyzers designed for high volume OL-HDF; cellulose triacetate (TAGP) and polysulphone (PS), and polyvinylpyrrolidone (PVP)...
August 1, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/28762343/assessment-of-maternal-risk-factors-and-its-relationship-with-early-childhood-caries-among-preschool-children-in-mangaluru-city
#10
Sham S Bhat, Sundeep Hegde, Vidya Bhat, K M Ramya, Praveen Jodalli
AIM: The aim of this study is to assess the maternal risk factors and its relationship with early childhood caries (ECC) among preschoolchildren in Mangaluru city. METHODS: Children aged 3-5 years attending preschool (Anganwadi) and their mothers were included in the study. A total of 120 child-mother pairs participated in the study. The maternal risk factors were assessed by a pretested questionnaire. After obtaining the consent, the mother and their children were clinically examined for dental caries using the WHO criteria (1997)...
July 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28759394/impact-of-prolonged-breastfeeding-on-dental-caries-a-population-based-birth-cohort-study
#11
Karen Glazer Peres, Gustavo G Nascimento, Marco Aurelio Peres, Murthy N Mittinty, Flavio Fernando Demarco, Ina Silva Santos, Alicia Matijasevich, Aluisio J D Barros
BACKGROUND: Few studies have assessed the effect of breastfeeding, bottle feeding, and sugar consumption on children's dental caries. We investigated whether the duration of breastfeeding is a risk factor for dental caries in the primary dentition, independently of sugar consumption. METHODS: An oral health study (n = 1303) nested in a birth cohort study was carried out in southern Brazil. The average number of decayed, missing, and filled primary tooth surfaces (dmfs) and severe early childhood caries (S-ECC: dmfs ≥6) were investigated at age 5 years...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28757866/efficacy-safety-and-overall-quality-of-life-of-endoscopic-submucosal-dissection-for-early-colorectal-cancer-in-elderly-patients
#12
Liang Liu, Xingjie Shen, Jingyu Zhu
PURPOSE: Studies reporting the treatment of early colorectal cancer (ECC) by endoscopic submucosal dissection (ESD) in elderly patients are lacking in China. The aim was to evaluate the efficacy, safety and overall quality of life of elderly patients with ECC who undergoing ESD. METHODS: Three hundred and seventy-nine patients with 401 colorectal lesions entered into our study from March 2013 to March 2016 (Patients with an age 70 years old or older were divided into the elderly group and those who were less than 70-year-old entered the non-elderly group)...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28753454/long-noncoding-rna-pcat1-regulates-extrahepatic-cholangiocarcinoma-progression-via-the-wnt-%C3%AE-catenin-signaling-pathway
#13
Fumin Zhang, Ming Wan, Yi Xu, Zhenglong Li, Kaiming Leng, Pengcheng Kang, Yunfu Cui, Xingming Jiang
Extrahepatic cholangiocarcinoma (ECC) is a deadly disease that often responds poorly to conventional chemotherapy or radiotherapy. Long noncoding RNAs (lncRNAs) play important roles in human cancers, including ECC, and recent studies indicated that the lncRNA prostate cancer-associated transcript 1 (non-protein coding) (PCAT1) is involved in multiple cancers. However, the role of PCAT1 in ECC is unclear. Previously, we showed that PCAT1 is up-regulated in both ECC tissue samples and cell lines. Here, we showed that downregulation of PCAT1 following transfection with silencing RNA reduced ECC cell growth and increased cell apoptosis...
July 25, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28747744/predicting-trend-of-early-childhood-caries-in-mainland-china-a-combined-meta-analytic-and-mathematical-modelling-approach-based-on-epidemiological-surveys
#14
Xiaonan Zhang, Lei Zhang, Yonghong Zhang, Zhaoying Liao, Jinlin Song
Early childhood caries (ECC) is the most common chronic disease in young children. A reliable predictive model for ECC prevalence is needed in China as a decision supportive tool for planning health resources. In this study, we first established the autoregressive integrated moving average (ARIMA) model and grey predictive model (GM) based on the estimated national prevalence of ECC with meta-analysis from the published articles. The pooled data from 1988 to 2010 were used to establish the model, while the data from 2011 to 2013 were used to validate the models...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28742540/comparison-of-tissue-yield-using-frictional-fabric-brush-versus-sharp-curettage-for-endocervical-curettage
#15
Justin T Diedrich, Sumra Rathore, Joel S Bentz
OBJECTIVE: The aim of the study was to evaluate and compare the diagnostic yield of conventional endocervical curettage (ECC) with fabric-based ECC in a consistent physician group. MATERIALS AND METHODS: This is a retrospective case-control study of patients who underwent ECC both before and after introduction of a fabric-based ECC device. Histologic examination of curettings was categorized as satisfactory, limited, or inadequate. The Kruskall-Wallis test was used to compare proportions of gross descriptions and final diagnoses between groups...
July 25, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28737588/longer-concentric-action-increases-muscle-activation-and-neuromuscular-fatigue-responses-in-protocols-equalized-by-repetition-duration
#16
Lucas T Lacerda, Cinara G Costa, Fernando V Lima, Hugo C Martins-Costa, Rodrigo C R Diniz, André G P Andrade, Gustavo H C Peixoto, Michael G Bemben, Mauro H Chagas
The aim of this study was to investigate the impact of protocols equalized by the repetition duration but composed of different concentric and eccentric durations on muscle activation and neuromuscular fatigue. Seventeen males with previous experience in resistance training performed 3 training protocols (A - 2s con : 4s ecc; B - 3s con : 3s ecc; and C - 4s con : 2s ecc) with the Smith machine bench press exercise, all with 3 sets, 6 repetitions, 3 minutes' rest, and 60% of 1RM. The normalized root mean square of the electromyographic signal (EMGRMS) and mean frequency electromyography (EMGMF) for pectoralis major and triceps brachii muscles were calculated for 2nd and 5th repetitions in each set...
July 19, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28736270/prevalence-of-and-risk-factors-for-carriage-of-carbapenem-resistant-enterobacteriaceae-among-hospitalized-patients-in-japan
#17
Norihisa Yamamoto, Rumiko Asada, Ryuji Kawahara, Hideharu Hagiya, Yukihiro Akeda, Rathina Kumar Shanmuga Kani, Hisao Yoshida, Satomi Yukawa, Kouji Yamamoto, Yoshihiro Takayama, Hiroaki Ohnishi, Takashi Taniguchi, Taro Matsuoka, Katsura Matsunami, Isao Nishi, Tetsuo Kase, Shigeyuki Hamada, Kazunori Tomono
BACKGROUND: The prevalence of carbapenem-resistant Enterobacteriaceae (CRE) has been reported to be lower in Japan than in many other countries. However, extensive surveillance for CRE carriage has not been performed in Japan. AIM: To investigate the prevalence of CRE carriage in Japan among convalescent patients considered to be at high-risk of being CRE carriers using an improved selective culture medium. METHODS: A cross-sectional survey was conducted in 22 acute care hospitals (ACHs) and 21 long-term care hospitals (LTCHs) in northern Osaka from December 2015 to January 2016...
July 20, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28731879/peripheral-endothelial-cell-count-is-a-predictor-of-disease-severity-in-advanced-fuchs-endothelial-corneal-dystrophy
#18
Zeba A Syed, Jennifer A Tran, Ula V Jurkunas
PURPOSE: In advanced Fuchs endothelial corneal dystrophy (FECD), central endothelial changes do not correlate with disease severity. The peripheral endothelial cell count (ECC) has not been studied as a marker of FECD severity. The goal of this study was to determine the relationship between the peripheral ECC and known clinical markers of FECD in advanced cases. METHODS: Patients with FECD examined between January 1, 2013, and September 1, 2016, by 1 cornea specialist were identified...
July 19, 2017: Cornea
https://www.readbyqxmd.com/read/28725197/skeletal-muscle-remodeling-in-response-to-eccentric-vs-concentric-loading-morphological-molecular-and-metabolic-adaptations
#19
REVIEW
Martino V Franchi, Neil D Reeves, Marco V Narici
Skeletal muscle contracts either by shortening or lengthening (concentrically or eccentrically, respectively); however, the two contractions substantially differ from one another in terms of mechanisms of force generation, maximum force production and energy cost. It is generally known that eccentric actions generate greater force than isometric and concentric contractions and at a lower metabolic cost. Hence, by virtue of the greater mechanical loading involved in active lengthening, eccentric resistance training (ECC RT) is assumed to produce greater hypertrophy than concentric resistance training (CON RT)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28721668/quantitative-analysis-of-s-mutans-lactobacillus-and-bifidobacterium-found-in-initial-and-mature-plaques-in-thai-children-with-early-childhood-caries
#20
K Mitrakul, S Chanvitan, A Jeamset, K Vongsawan
AIMS: To quantify Streptococcus mutans, lactobacillus and bifidobacterium in initial and mature plaque collected from children with severe early childhood caries (S-ECC) and caries-free (CF) groups and to analyse the association between these bacteria and caries-related factors in each group. STUDY DESIGN: A collection of 120 initial and overnight supra-gingival plaques were collected from Thai children aged 2-5 years-old (S-ECC = 60, CF = 60). Plaque, gingival indices and decayed, missing, filled tooth (dmft) scores were recorded...
July 18, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
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