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https://www.readbyqxmd.com/read/29166256/infection-free-clinical-response-among-patients-with-hidradenitis-suppurativa-who-were-treated-with-adalimumab-results-from-two-phase-3-studies
#1
Evangelos J Giamarellos-Bourboulis, Jeffrey Sobell, Caitriona Ryan, Pierre J Wolkenstein, Ziqian Geng, Gerit D Mulder
OBJECTIVE: The objective of this study is to assess the rates of infection-free achievement of hidradenitis suppurativa clinical response (HiSCR) using integrated data from 2 phase 3, placebo-controlled trials, PIONEER I and II. MATERIALS AND METHODS: Analyses from the first 12 weeks of both studies were examined. Patients were randomized to receive adalimumab (ADA) or placebo, and they then were assessed in the clinic at weeks 0, 2, 4, 8, and 12. All reports of an adverse or serious adverse event and infection were classified as treatment-emergent adverse events (TEAEs)...
November 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29166182/increasing-confidence-and-ability-in-implementing-kangaroo-mother-care-method-among-young-mothers
#2
Eleni Kenanga Purbasary, Yeni Rustina, Tri Budiarti
Mothers giving birth to low birth weight babies (LBWBs) have low confidence in caring for their babies because they are often still young and may lack the knowledge, experience, and ability to care for the baby. This research aims to determine the effect of education about kangaroo mother care (KMC) on the confidence and ability of young mothers to implement KMC. The research methodology used was a controlled-random experimental approach with pre- and post-test equivalent groups of 13 mothers and their LBWBs in the intervention group and 13 mothers and their LBWBs in the control group...
2017: Compr Child Adolesc Nurs
https://www.readbyqxmd.com/read/29165934/first-rapid-assessment-of-avoidable-blindness-survey-in-the-maldives-prevalence-and-causes-of-blindness-and-cataract-surgery
#3
Ubeydulla Thoufeeq, Taraprasad Das, Hans Limburg, Maharshi Maitra, Lapam Panda, Asim Sil, John Trevelyan, Yuddha Sapkota
PURPOSE: A nationwide rapid assessment of avoidable blindness survey was undertaken in the Maldives among people aged 50 years or more to assess the prevalence and causes of blindness and visual impairment, cataract surgical coverage, cataract surgery outcome, and barriers to uptake of cataract surgical services. DESIGN: Prospective population-based study. METHODS: In the cluster sampling probability proportionate to size method, 3100 participants in 62 clusters across all 20 atolls were enrolled through house-to-house visits...
November 22, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29165789/medicaid-cost-savings-of-a-preventive-home-visit-program-for-disabled-older-adults
#4
Sarah L Szanton, Y Natalia Alfonso, Bruce Leff, Jack Guralnik, Jennifer L Wolff, Ian Stockwell, Laura N Gitlin, David Bishai
BACKGROUND/OBJECTIVES: Little is known about cost savings of programs that reduce disability in older adults. The objective was to determine whether the Community Aging in Place, Advancing Better Living for Elders (CAPABLE) program saves Medicaid more money than it costs to provide. DESIGN: Single-arm clinical trial (N = 204) with a comparison group of individuals (N = 2,013) dually eligible for Medicaid and Medicare matched on baseline geographic and demographic characteristics, chronic conditions, and healthcare use...
November 22, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29165309/clinical-characteristics-of-patients-with-dizziness-after-motor-vehicle-accident
#5
Min Bum Kim, Suk Won Chang, Gil Chai Lim, Chan Il Song
OBJECTIVE: The purpose of this study was to identify the clinical characteristics of dizziness occurring after a motor vehicle accident. MATERIALS AND METHODS: We retrospectively analyzed 217 patients who had visited a tertiary medical center complaining of dizziness after a motor vehicle accident between January 2009 and December 2014. Of the 217 patients, we enrolled 54 patients who had undergone a vestibular function test and had no definite evidence of fracture of the temporal bone or intracranial lesions...
November 21, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29164841/home-blood-pressure-measurement-as-a-systematic-tool-for-clinical-practice-in-ckd-patients-a-real-world-picture
#6
Adamasco Cupisti, Lorenzo Ghiadoni, Claudia Zullo, Michele Marchini, Enrico Varricchio, Alessandro Puntoni, Elisabetta Giglio, Ophelia Meniconi, Maria R Bruno, Maria F Egidi
BACKGROUND: Arterial hypertension is very common in chronic kidney disease (CKD) patients and its prevalence increases with lowering estimated glomerular filtration rate (eGFR). Blood pressure (BP) control is a cornerstone in the treatment of CKD patients but still most treatment decisions are based on office BP measurement (OBPM). The aim of this cross-sectional, retrospective study is to investigate the prevalence of hypertension phenotypes in CKD patients and whether different home (HBPM) or OBPM are associated with a different CKD stage and cardiovascular comorbidities...
November 22, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/29164830/changes-in-erectile-function-after-photoselective-vaporization-of-the-prostate-with-a-120-w-greenlight-high-performance-system-laser-2-year-follow-up
#7
Juhyun Park, Sung Yong Cho, Min Chul Cho, Hyeon Jeong, Hwancheol Son
PURPOSE: To evaluate the impact of photoselective vaporization of the prostate (PVP) with a 120-W GreenLight high-performance system on erectile function in a 2-year follow-up study. MATERIALS AND METHODS: One hundred seventy-seven patients who underwent PVP during 2008 to 2012 were analyzed retrospectively. The patients were divided into 5 groups according to their preoperative 5-item International Index of Erectile Function (IIEF-5) scores: Group I (IIEF-5: 5~7, n=28), II (IIEF-5: 8~11, n=47), III (IIEF-5: 12~16, n=43), IV (IIEF-5: 17~21, n=34), and V (IIEF-5: 22~25, n=25)...
November 16, 2017: World Journal of Men's Health
https://www.readbyqxmd.com/read/29164723/double-blind-placebo-controlled-trial-of-the-effect-of-omalizumab-on-basophils-in-chronic-urticaria-patients
#8
Lukas Jörg, Tatjana Pecaric-Petkovic, Stephan Reichenbach, Michael Coslovsky, Odile Stalder, Werner Pichler, Oliver Hausmann
BACKGROUND: Omalizumab has been shown to be effective in treating chronic spontaneous urticaria (CSU). The reduction of FcεRI receptor density on the surface of basophils and mast cells is thought to play a major role in its effectiveness. We conducted a double-blind, randomized, placebo-controlled trial to investigate the mode of action of omalizumab in patients with antihistamine-resistant CSU. METHODS: Thirty patients were randomized in a 2:1 ratio to receive either 300 mg omalizumab or placebo...
November 22, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29164179/schroth-physiotherapeutic-scoliosis-specific-exercises-for-adolescent-idiopathic-scoliosis-how-many-patients-require-treatment-to-prevent-one-deterioration-results-from-a-randomized-controlled-trial-sosort-2017-award-winner
#9
Sanja Schreiber, Eric C Parent, Doug L Hill, Douglas M Hedden, Marc J Moreau, Sarah C Southon
Background: Recent randomized controlled trials (RCTs) support using physiotherapeutic scoliosis-specific exercises (PSSE) for adolescents with idiopathic scoliosis (AIS). All RCTs reported statistically significant results favouring PSSE but none reported on clinical significance. The number needed to treat (NNT) helps determine if RCT results are clinically meaningful. The NNT is the number of patients that need to be treated to prevent one bad outcome in a given period. A low NNT suggests that a therapy has positive outcomes in most patients offered the therapy...
2017: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/29164115/cross-sectional-associations-of-fatigue-with-cerebral-%C3%AE-amyloid-in-older-adults-at-risk-of-dementia
#10
Claudie Hooper, Philipe De Souto Barreto, Nicola Coley, Matteo Cesari, Pierre Payoux, Anne Sophie Salabert, Sandrine Andrieu, Bruno Vellas
Fatigue is a common symptom in the elderly and has also been associated with impaired cognition in older adults. Hence, we sought to explore the cross-sectional relationship between fatigue and cerebral β-amyloid (Aβ) in 269 elderly individuals reporting subjective memory complaints from the Multidomain Alzheimer Preventive Trial. Standard uptake value ratios (SUVRs) were generated by [(18)F] florbetapir positron emission tomography (PET) using the cerebellum as a reference. Cortical-to-cerebellar SUVRs (cortical-SUVRs) were obtained using the mean signal from the frontal cortex, temporal cortex, parietal cortex, precuneus, anterior cingulate, and posterior cingulate...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29164013/physician-adherence-to-sexually-transmitted-infection-screening-guidelines-in-an-ob-gyn-teaching-clinic-in-hawai-i
#11
Alyssa Dee P Carlson, Mary Tschann, Somsook Santibenchakul, Eric L Hurwitz, Jennifer Salcedo
Rates of chlamydia (CT) and gonorrhea (GC) have risen for the first time in the United States since 2006. Certain population groups are disproportionately affected by these sexually transmitted infections (STIs) as well as HIV. The Centers for Disease Control and Prevention (CDC) and professional societies have published screening guidelines for these STIs for women under the age of 25. We aimed to quantify physician adherence to GC/CT and HIV screening guidelines and to determine demographic factors associated with GC/CT and HIV screening recommendations among women 14-25 years old in Honolulu, Hawai'i...
November 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/29164002/biological-therapy-in-arthritis-patients-with-hepatitis-b-or-c-infection-a-multicenter-retrospective-case-series
#12
Sultana Abdulaziz, Hussein Halabi, Mohammed A Omair, Suzan Attar, Abdullah Alghamdi, Mohammed Shabrawishi, Abdulwahab Neyazi, Haneen Alnazzawi, Nuha Meraiani, Hani Almoallim
Objective: Reactivation of viral hepatitis B (HBV) and C (HCV) has been reported in various case reports of patients with arthritis on biological therapy. The objective of this study was to describe the clinical characteristics and outcomes of arthritis patients with HBV or HCV treated with biological therapy. Material and Methods: This is a retrospective case series including all patients above 13 years of age with arthritis patients from four centers in Saudi Arabia with concurrent chronic viral hepatitis infection (HBV or HCV) who received biological agents in the rheumatology clinics during their course of their disease from duration of the disease onset until last outpatient visit up to November 2015...
September 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/29163938/understanding-biological-mechanisms-underlying-adverse-birth-outcomes-in-developing-countries-protocol-for-a-prospective-cohort-amanhi-bio-banking-study
#13
Abdullah H Baqui, Rasheda Khanam, Mohammad Sayedur Rahman, Aziz Ahmed, Hasna Hena Rahman, Mamun Ibne Moin, Salahuddin Ahmed, Fyezah Jehan, Imran Nisar, Atiya Hussain, Muhammad Ilyas, Aneeta Hotwani, Muhammad Sajid, Shahida Qureshi, Anita Zaidi, Sunil Sazawal, Said M Ali, Saikat Deb, Mohammed Hamad Juma, Usha Dhingra, Arup Dutta, Shaali Makame Ame, Caroline Hayward, Igor Rudan, Mike Zangenberg, Donna Russell, Sachiyo Yoshida, Ozren Polašek, Alexander Manu, Rajiv Bahl
Objectives: The AMANHI study aims to seek for biomarkers as predictors of important pregnancy-related outcomes, and establish a biobank in developing countries for future research as new methods and technologies become available. Methods: AMANHI is using harmonised protocols to enrol 3000 women in early pregnancies (8-19 weeks of gestation) for population-based follow-up in pregnancy up to 42 days postpartum in Bangladesh, Pakistan and Tanzania, with collection taking place between August 2014 and June 2016...
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29163937/development-and-validation-of-a-simplified-algorithm-for-neonatal-gestational-age-assessment-protocol-for-the-alliance-for-maternal-newborn-health-improvement-amanhi-prospective-cohort-study
#14
Abdullah Baqui, Parvez Ahmed, Sushil Kanta Dasgupta, Nazma Begum, Mahmoodur Rahman, Nasreen Islam, Mohammad Quaiyum, Betty Kirkwood, Karen Edmond, Caitlin Shannon, Samuel Newton, Lisa Hurt, Fyezah Jehan, Imran Nisar, Atiya Hussain, Naila Nadeem, Muhammad Ilyas, Anita Zaidi, Sunil Sazawal, Saikat Deb, Arup Dutta, Usha Dhingra, Said Moh'd Ali, Davidson H Hamer, Katherine Ea Semrau, Marina Straszak-Suri, Caroline Grogan, Godfrey Bemba, Anne Cc Lee, Blair J Wylie, Alexander Manu, Sachiyo Yoshida, Rajiv Bahl
Objective: The objective of the Alliance for Maternal and Newborn Health Improvement (AMANHI) gestational age study is to develop and validate a programmatically feasible and simple approach to accurately assess gestational age of babies after they are born. The study will provide accurate, population-based rates of preterm birth in different settings and quantify the risks of neonatal mortality and morbidity by gestational age and birth weight in five South Asian and sub-Saharan African sites...
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29163845/improved-medical-expenditure-and-survival-with-integration-of-traditional-chinese-medicine-treatment-in-patients-with-heart-failure-a-nationwide-population-based-cohort-study
#15
Ming-Yen Tsai, Wen-Long Hu, Jen-Huai Chiang, Yu-Chuen Huang, Shih-Yu Chen, Yu-Chiang Hung, Yung-Hsiang Chen
Background: No previous studies have evaluated the effects of traditional Chinese medicine (TCM) treatment on patients with heart failure (HF). Hence, in this study, we determined whether TCM treatment affects the healthcare burden and survival of HF patients. Methods: Samples were retrieved from the registry of catastrophic illness patients of the Taiwan National Health Insurance Research Database (NHIRD). Based on a frequency (1:1) matched case-control design, patients with HF between 2000 and 2010 were designated as cases (TCM users) and controls (non-TCM users)...
October 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/29162989/a-retrospective-study-on-the-outcomes-of-ahmed-valve-versus-ahmed-valve-combined-with-fluocinolone-implant-in-uveitic-glaucoma
#16
Duriye D Sevgi, Samaneh Davoudi, Katherine E Talcott, Heeyoon Cho, Rong Guo, Ann-Marie Lobo, George N Papaliodis, Angela Turalba, Lucia Sobrin, Lucy Q Shen
Purpose: To compare the intraocular pressure (IOP) outcomes of Ahmed glaucoma valve (AGV) surgery alone versus AGV with fluocinolone implant in uveitic glaucoma patients. Methods: We identified uveitic glaucoma patients with AGV surgery alone and AGV surgery combined with fluocinolone implant from the Massachusetts Eye and Ear Ocular Inflammation Database. Demographic information, visual acuity, and IOP were recorded at preoperative visits and 1, 6, and 12 months after surgery...
2017: Digital Journal of Ophthalmology: DJO
https://www.readbyqxmd.com/read/29162340/effects-of-intensive-blood-pressure-treatment-on-acute-kidney-injury-events-in-the-systolic-blood-pressure-intervention-trial-sprint
#17
Michael V Rocco, Kaycee M Sink, Laura C Lovato, Dawn F Wolfgram, Thomas B Wiegmann, Barry M Wall, Kausik Umanath, Frederic Rahbari-Oskoui, Anna C Porter, Roberto Pisoni, Cora E Lewis, Julia B Lewis, James P Lash, Lois A Katz, Amret T Hawfield, William E Haley, Barry I Freedman, Jamie P Dwyer, Paul E Drawz, Mirela Dobre, Alfred K Cheung, Ruth C Campbell, Udayan Bhatt, Srinivasan Beddhu, Paul L Kimmel, David M Reboussin, Glenn M Chertow
BACKGROUND: Treating to a lower blood pressure (BP) may increase acute kidney injury (AKI) events. STUDY DESIGN: Data for AKI resulting in or during hospitalization or emergency department visits were collected as part of the serious adverse events reporting process of the Systolic Blood Pressure Intervention Trial (SPRINT). SETTING & PARTICIPANTS: 9,361 participants 50 years or older with 1 or more risk factors for cardiovascular disease...
November 18, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29162073/patient-navigation-to-improve-diabetes-outpatient-care-at-a-safety-net-hospital-a-retrospective-cohort-study
#18
Michal Horný, Wiljeana Glover, Gouri Gupte, Aruna Saraswat, Varsha Vimalananda, James Rosenzweig
BACKGROUND: Recent emphasis on value based care and population management, such as Accountable Care Organizations in the United States, promote patient navigation to improve the quality of care and reduce costs. Evidence supporting the efficacy of patient navigation for chronic disease care is limited. The objective of this study was to evaluate the effect of a patient navigation program on medical and administrative outcomes among patients with diabetes in an urban, safety-net hospital clinic setting...
November 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29161951/an-open-treatment-six-week-study-of-the-clinical-effectiveness-of-paliperidone-palmitate-in-schizophrenia-data-from-acute-units-in-spain-shadow-study
#19
Eduard Parellada, Miquel Bioque, Manuel Serrano, Berta Herrera, Marta García Dorado
OBJECTIVES: To evaluate clinical evolution of patients with schizophrenia admitted in acute units because of a relapse and treated with once-monthly Paliperidone Palmitate (PP1M). METHODS: This multicentre, open-label, prospective observational study followed patients with schizophrenia treated with PP1M in acute psychiatric units for up to 6 weeks. RESULTS: Out of the 280 enrolled patients, 61 received PP1M as antipsychotic monotherapy, and 219 in combination with other antipsychotics...
November 21, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/29161530/family-centered-breastfeeding-education-to-promote-primiparas-exclusive-breastfeeding-in-china
#20
Jian Ke, Yan-Qiong Ouyang, Sharon R Redding
BACKGROUND: Few breastfeeding education programs focus on primiparas and the importance of family members on exclusive breastfeeding in China. Research aim: This study aimed to explore the influence of a family-centered breastfeeding education program in promoting exclusive breastfeeding up to 6 months postpartum and to improve women's attitude and knowledge, family members' knowledge, and family support. METHODS: This was a two-group quasi-experimental design with multiple comparisons...
November 1, 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
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