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Omega 3 fish oil

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https://www.readbyqxmd.com/read/29674850/effect-of-dietary-oils-on-peripheral-neuropathy-related-endpoints-in-dietary-obese-rats
#1
Lawrence Coppey, Eric Davidson, Hanna Shevalye, Michael E Torres, Mark A Yorek
Purpose: This study aimed to determine the effect of dietary oils (olive, safflower, evening primrose, flaxseed, or menhaden) enriched in different mono unsaturated fatty acids or polyunsaturated fatty acids on peripheral neuropathies in diet-induced obese Sprague-Dawley rats. Materials and methods: Rats at 12 weeks of age were fed a high-fat diet (45% kcal) for 16 weeks. Afterward, the rats were fed diets with 50% of the kilocalories of fat derived from lard replaced by the different dietary oils...
2018: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/29673917/influence-of-omega-3-polyunsaturated-fatty-acids-from-fish-oil-or-meal-on-the-structure-of-lipid-microdomains-in-bovine-luteal-cells
#2
M R Plewes, P D Burns, P E Graham, J E Bruemmer, T E Engle
Biological membranes are composed of a lipid bilayer and proteins that form lipid microdomains. This study examined the effects of fish byproducts on lipid-protein interactions within lipid microdomains of bovine luteal cells. In Exp. 1 and 2, luteal cells were prepared from corpora lutea (CL; n = 4 to 8) collected at an abattoir. Exp. 1 was conducted to optimize ultrasonication in a detergent-free protocol for isolation of lipid microdomains. A power setting of 10 to 20% was effective in isolating lipid microdomains from bulk lipid...
March 31, 2018: Animal Reproduction Science
https://www.readbyqxmd.com/read/29673542/maternal-nutritional-supplementation-with-fish-oil-and-or-leucine-improves-hepatic-function-and-antioxidant-defenses-and-minimizes-cachexia-indexes-in-walker-256-tumor-bearing-rats-offspring
#3
Natália Angelo da Silva Miyaguti, Sarah Christine Pereira de Oliveira, Maria Cristina Cintra Gomes-Marcondes
In this study, we hypothesized that throughout the pregnancy/weaning period, nutritional supplementation with leucine (which improves protein synthesis) and/or fish oil (rich in omega-3, which modulates oxidative stress) can minimize/improve cachexia-induced damage in rat offspring. Thus, we investigated the maternal supplementation with these nutrients over the modulation of cachexia index and liver function in tumor-bearing rats offspring. Pregnant rats were fed control, leucine, omega-3, and leucine/omega-3 diets, which were given throughout the gestational and weaning periods...
March 2018: Nutrition Research
https://www.readbyqxmd.com/read/29673104/omega-3-polyunsaturated-fatty-acid-supplementation-reduces-blood-pressure-but-not-renal-vasoconstrictor-response-to-orthostatic-stress-in-healthy-older-adults
#4
Christine M Clark, Kevin D Monahan, Rachel C Drew
Older adults exhibit augmented renal vasoconstriction during orthostatic stress compared to young adults. Consumption of omega-3 polyunsaturated fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) found in fish oil (FO), modulates autonomic nerve activity. However, the effect of omega-3 polyunsaturated fatty acid consumption on the renal vasoconstrictor response to orthostatic stress in young and older adults is unknown. Therefore, 10 young (25 ± 1 years; mean ± SEM) and 10 older (66 ± 2 years) healthy adults ingested 4 g FO daily for 12 weeks, and underwent graded lower body negative pressure (LBNP; -15 and -30 mmHg) pre- and post-FO supplementation...
April 2018: Physiological Reports
https://www.readbyqxmd.com/read/29668864/bovine-embryo-elongation-is-altered-due-to-maternal-fatty-acid-supplementation
#5
K Giller, B Drews, J Berard, H Kienberger, M Schmicke, J Frank, B Spanier, H Daniel, G Geisslinger, S E Ulbrich
The pre-implantation period is prone to embryonic losses in bovine. Embryo-maternal communication is crucial to support embryo development. Thereby, factors of the uterine fluid (UF) are of specific importance. The maternal diet can affect the UF composition. Since omega 3 fatty acids (omega 3 FA) are considered to be beneficial for reproduction, we investigated if dietary omega 3 FA affected factors in the UF related to embryo elongation. Angus heifers (n = 37) were supplemented with either 450 g of rumen-protected fish oil (omega 3 FA) or sunflower oil (omega 6 FA) for a period of 8 weeks...
April 12, 2018: Biology of Reproduction
https://www.readbyqxmd.com/read/29665653/upregulation-of-ppar-%C3%AE-mediates-the-renoprotective-effect-of-omega-3-pufa-and-ferulic-acid-in-gentamicin-intoxicated-rats
#6
Nahla E El-Ashmawy, Naglaa F Khedr, Hoda A El-Bahrawy, Sara A Helal
Ferulic acid (FrA) is a natural product containing phenolic compounds. ω-3 PUFA is the major constituent of fish oil. The aim of this study was to investigate the renoprotective role of FrA and FO in gentamicin (GM)-induced nephrotoxicity in rats. Forty four male rats were divided equally into 4 groups: Control group, GM group, FrA + GM group and FO + GM group. Each of the treated groups was injected with GM (40 mg/kg) i.p. for 9 consecutive days. FrA (100 mg/kg) and FO (5 mL/kg) were given to rats orally daily for 10 days prior to GM and then concomitantly with GM for additional 9 days...
March 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29656385/improving-the-lipid-profile-of-ready-to-cook-meat-products-by-addition-of-omega-3-microcapsules-effect-on-oxidation-and-sensory-analysis
#7
Trinidad Pérez-Palacios, Jorge Ruiz, Estefanía Jiménez-Martín, Juan Carlos Solomando, Teresa Antequera
BACKGROUND: The omega-3 enrichment of ready-to-cook meat products by microencapsulated fish oil addition was analyzed in this study. For that, three batches of chicken nuggets were prepared: control (C), enriched in bulk fish oil (BFO) and with added microencapsulated fish oil (MFO). Sensory features, acceptability, oxidative stability and volatile compounds were analyzed. RESULTS: MFO nuggets did not differ in any sensory trait with C ones. BFO showed increased juiciness and saltiness but decreased meat flavor...
April 15, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29652551/n-3-fatty-acid-supplementation-for-the-treatment-of-dry-eye-disease
#8
(no author information available yet)
Background Dry eye disease is a common chronic condition that is characterized by ocular discomfort and visual disturbances that decrease quality of life. Many clinicians recommend the use of supplements of n-3 fatty acids (often called omega-3 fatty acids) to relieve symptoms. Methods In a multicenter, double-blind clinical trial, we randomly assigned patients with moderate-to-severe dry eye disease to receive a daily oral dose of 3000 mg of fish-derived n-3 eicosapentaenoic and docosahexaenoic acids (active supplement group) or an olive oil placebo (placebo group)...
April 13, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29627068/role-of-fish-oil-in-post-cardiotomy-bleeding-a-summary-of-the-basic-science-and-clinical-trials
#9
REVIEW
John Alfred Carr
BACKGROUND: Omega-3 fatty acids are widely used. This article reviews the coagulopathic effects of fish oil. METHODS: A review was performed of all English articles that addressed the topic from 1980 to 2017. RESULTS: Fish oil induces an in vitro coagulopathy in humans due to inhibitory effects in platelet-to-platelet adhesion and platelet-stimulated thrombin generation. The effect from fish oil alone is weak, but it is enhanced and may become clinically noticeable in patients taking antiplatelet therapy, and, to a lesser extent, in patients on factor Xa inhibitors and warfarin...
April 4, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29615288/cardiac-effects-of-fish-oil-in-a-rat-model-of-streptozotocin-induced-diabetes
#10
F Mayyas, R Jaradat, K H Alzoubi
BACKGROUND AND AIMS: Fish oil (FO) is rich in omega-3 polyunsaturated fatty acids, which have cardio-protective effects. This study aims to evaluate effects of FO in a rat model of streptozotocin (STZ) induced diabetes. METHODS AND RESULTS: Adults male Wistar rats were assigned to control (4 μl corn oil/g corn oil given by oral gavage), FO (4 μl Menhaden FO/g body weight given by oral gavage), diabetes (DM, 35 mg/kg STZ single intraperitoneal injection, corn oil), and DM + FO groups for 8 weeks...
February 25, 2018: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29599972/effects-of-fish-and-krill-oil-on-gene-expression-in-peripheral-blood-mononuclear-cells-and-circulating-markers-of-inflammation-a-randomised-controlled-trial
#11
Amanda Rundblad, Kirsten B Holven, Inge Bruheim, Mari C Myhrstad, Stine M Ulven
Marine n -3 (omega-3) fatty acids alter gene expression by regulating the activity of transcription factors. Krill oil is a source of marine n -3 fatty acids that has been shown to modulate gene expression in animal studies; however, the effect in humans is not known. Hence, we aimed to compare the effect of intake of krill oil, lean and fatty fish with a similar content of n -3 fatty acids, and high-oleic sunflower oil (HOSO) with added astaxanthin on the expression of genes involved in glucose and lipid metabolism and inflammation in peripheral blood mononuclear cells (PBMC) as well as circulating inflammatory markers...
2018: Journal of Nutritional Science
https://www.readbyqxmd.com/read/29579909/determining-quality-parameters-of-fish-oils-by-means-of-1-h-nuclear-magnetic-resonance-mid-infrared-and-near-infrared-spectroscopy-in-combination-with-multivariate-statistics
#12
Editha Giese, Ole Winkelmann, Sascha Rohn, Jan Fritsche
Fish oil is becoming increasingly popular as a dietary supplement as well as for its use in animal feed, which is mainly due to its high contents of the health promoting omega-3 fatty acids. However, these polyunsaturated fatty acids are highly susceptible to oxidation, which results in a decrease of the fish oil quality. This study investigated the potential of1 H NMR, FT-MIR, and FT-NIR spectroscopy in the quality assessment of fish oils. A total of 84 different fish oils, of which 22 were subjected to accelerated storage with varying temperature and light exposure, were used to develop models for predicting the peroxide value (PV), the anisidine value (AnV), and the acid value (AV)...
April 2018: Food Research International
https://www.readbyqxmd.com/read/29569345/fish-oil-treatment-reduces-chronic-alcohol-exposure-induced-synaptic-changes
#13
Zhe Shi, Youna Xie, Huixia Ren, Baixuan He, Meng Wang, Jian-Bo Wan, Ti-Fei Yuan, Xiaoli Yao, Huanxing Su
Alcohol addiction is a chronic neuropsychiatric disorder that represents one of the most serious global public health problems. Yet, currently there still lacks an effective pharmacotherapy. Omega-3 polyunsaturated fatty acids (N-3 PUFAs) have exhibited beneficial effects in a variety of neurological disorders, particularly in reversing behavioral deficits and neurotoxicity induced by prenatal alcohol exposure and binge drinking. In the present study, we investigated if fish oil, which is rich in N-3 PUFAs, had beneficial effects on preventing relapse and alleviating withdrawal symptoms after chronic alcohol exposure...
March 22, 2018: Addiction Biology
https://www.readbyqxmd.com/read/29567223/modifications-of-atlantic-salmon-by-product-oil-for-obtaining-different-%C3%AF-3-polyunsaturated-fatty-acids-concentrates-an-approach-to-comparative-analysis
#14
Monjurul Haq, Seul-Ki Park, Min-Jung Kim, Yeon-Jin Cho, Byung-Soo Chun
Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) rich 2-monoacylglycerols (2-MAG), omega-3 polyunsaturated free fatty acids (ω-3 PUFFAs) concentrate, and PUFA enriched acylglycerols were prepared from salmon frame bone oil (SFBO) by enzymatic alcoholysis, urea complexation, and enzymatic esterification, respectively. The yields of 2-MAG, ω-3 PUFFAs concentrate, and PUFA enriched acylglycerols were 40.25, 16.52, and 15.65%, respectively. ω-3 PUFFAs concentrate and PUFA enriched acylglycerols showed darker red color than SFBO and 2-MAG due to aggregation of astaxanthin pigment in ω-3 PUFFAs concentrate during urea complexation...
April 2018: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/29548449/examination-of-marine-and-vegetable-oil-oxidation-data-from-a-multi-year-third-party-database
#15
Anna A De Boer, Adam Ismail, Keri Marshall, Gerard Bannenberg, Kevin L Yan, William J Rowe
Fish oil (FO) products constitute good sources of omega-3 fats. Oxidation data from a large third-party database of 1900 + globally-sourced FO samples were assessed. In FO products, for peroxide value (PV), 13.9% exceeded 5 mEq O2 /kg (2.2% >10); for acid value (AcV) 2.1% exceeded 3 mg KOH/g, while for p-anisidine value (pAV) in unflavoured oils, 6.1% exceeded 20, (3.8% >30), and 8.8% exceeded TOTOX limits (26). Additionally, we compared FO with other dietary oils. The FO median PV was similar to those of algal and sunflower oils, 4...
July 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29546292/fish-oil-supplementation-does-not-affect-cognitive-outcomes-in-cardiac-surgery-patients-in-the-omega-3-fatty-acids-for-prevention-of-post-operative-atrial-fibrillation-opera-trial
#16
James C Jackson, Dariush Mozaffarian, Amy J Graves, Nancy J Brown, Roberto Marchioli, Amy L Kiehl, E Wesley Ely
Background: Cognitive decline has been reported following cardiac surgery, leading to great interest in interventions to minimize its occurrence. Long-chain n-3 (ω-3) polyunsaturated fatty acids (PUFAs) have been associated with less cognitive decline in observational studies, yet no trials have tested the effects of n-3 PUFAs on cognitive decline after surgery. Objective: We sought to determine whether perioperative n-3 PUFA supplementation reduces postoperative cognitive decline in patients postcardiac surgery...
March 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29542390/vitamin-e-and-fish-oil-separately-or-in-combination-on-treatment-of-primary-dysmenorrhea-a-double-blind-randomized-clinical-trial
#17
Narges Sadeghi, Farnoush Paknezhad, Mohamadreza Rashidi Nooshabadi, Maria Kavianpour, Sima Jafari Rad, Hossein Khadem Haghighian
Primary dysmenorrhea is one of the most common complaints of women. The aim of this study was to investigate the adjuvant effect of vitamin E and omega-3 fatty acids, separately or in combination, supplements on pain in the treatment of primary dysmenorrhea. This clinical trial conducted on students of university. Qualified girls completed the VAS before randomization. Arrangement was determined according to the severity of the pain (mild 0-3; moderate 3.1-6; severe 6.1-10). One hundred patients were randomly assigned to four groups receiving omega-3 (n = 25), vitamin E (n = 25), vitamin E- omega-3 (n = 25), or placebo (n = 25)...
March 15, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29530030/chemical-composition-and-antibacterial-activity-of-oils-from-chrysicthys-nigrodigitatus-and-hepsetus-odoe-two-freshwater-fishes-from-yabassi-cameroon
#18
Mouokeu Raymond Simplice, Womeni Hilaire Macaire, Njike Ngamga Fabrice Hervé, Tonfack Djikeng Fabrice, Djopnang DJimbie Justin, Tchoumbougnang François, Kuiate Jules-Roger
BACKGROUNDS: Oils of fish origin are a very rich source of Omega - 3 and Omega - 6 fatty acids. They have been suggested to provide numerous health benefits for humans involving antimicrobial properties. Chrysichthys nigrodigitatus and Hepsetus odoe are two fishes well known in Cameroon. The chemical composition and the antibacterial activity of these fishes derived oils are unknown. The study was designed to valorise C. nigrodigitatus and H.s odoe oils activity against food poisoning bacteria...
March 12, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29515679/role-of-diet-in-influencing-rheumatoid-arthritis-disease-activity
#19
REVIEW
Humeira Badsha
Background: Patients with Rheumatoid Arthritis (RA) frequently ask their doctors about which diets to follow, and even in the absence of advice from their physicians, many patients are undertaking various dietary interventions. Discussion: However, the role of dietary modifications in RA is not well understood. Several studies have tried to address these gaps in our understanding. Intestinal microbial modifications are being studied for the prevention and management of RA...
2018: Open Rheumatology Journal
https://www.readbyqxmd.com/read/29510597/potential-roles-of-n-3-pufas-during-skeletal-muscle-growth-and-regeneration
#20
REVIEW
Bill Tachtsis, Donny Camera, Orly Lacham-Kaplan
Omega-3 polyunsaturated fatty acids (n-3 PUFAs), which are commonly found in fish oil supplements, are known to possess anti-inflammatory properties and more recently alter skeletal muscle function. In this review, we discuss novel findings related to how n-3 PUFAs modulate molecular signaling responsible for growth and hypertrophy as well as the activity of muscle stem cells. Muscle stem cells commonly known as satellite cells, are primarily responsible for driving the skeletal muscle repair process to potentially damaging stimuli, such as mechanical stress elicited by exercise contraction...
March 5, 2018: Nutrients
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