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https://www.readbyqxmd.com/read/28077638/a-conserved-glycine-residue-is-required-for-proper-functioning-of-a-baculovirus-vp39-protein
#1
Susumu Katsuma, Ryuhei Kokusho
: The baculovirus VP39 is a major nucleocapsid protein essential for viral propagation. However, the critical domains or residues of the VP39 protein have not yet been identified. Here, we performed mutagenesis experiments of Bombyx mori nucleopolyhedrovirus (BmNPV) using 5-bromo-2' -deoxyuridine and isolated a BmNPV mutant that produced fewer occlusion bodies than the wild-type virus. This mutant also produced fewer infectious budded viruses (BVs), when compared with the wild-type virus in both cultured cells and B...
January 11, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28076536/-quality-of-life-of-family-caregivers-of-adults-with-spinal-cord-injury-a-systematic-review
#2
Cejane Oliveira Martins Prudente, Maysa Ferreira Martins Ribeiro, Celmo Celeno Porto
The scope of this study was to analyze the quality of life of family caregivers of adults with spinal cord injury. Two researchers conducted a systematic review independently, based on articles published between 2000 to 2014, using the key words quality of life and caregivers or family and spinal cord, in Portuguese, English and Spanish. The search was conducted in the Virtual Health Library (BVS) and the United States National Library of Medicine (PubMED) databases. Caregivers of tetraplegics have a worse quality of life than caregivers of paraplegics...
January 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28076449/long-term-follow-up-of-patients-after-percutaneous-coronary-intervention-with-everolimus-eluting-bioresorbable-vascular-scaffold
#3
Rafael Alexandre Meneguz-Moreno, José de Ribamar Costa, Freddy Antônio Britto Moscoso, Rodolfo Staico, Luiz Fernando Leite Tanajura, Marinella Patrizia Centemero, Auréa Jacob Chaves, Andrea Claudia Leão de Sousa Abizaid, Amanda Guerra de Moraes Rego E Sousa, Alexandre Antonio Cunha Abizaid
Background: Bioresorbable vascular scaffolds (BVS) were developed to improve the long-term results of percutaneous coronary intervention, restoring vasomotion. Objectives: To report very late follow-up of everolimus-eluting Absorb BVS (Abbott Vascular, Santa Clara, USA) in our center. Methods: Observational retrospective study, in a single Brazilian center, from August 2011 to October 2013, including 49 patients submitted to Absorb BVS implantation...
January 9, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28069611/bioresorbable-vascular-scaffolds-for-the-treatment-of-chronic-total-occlusions-an-international-multicenter-registry
#4
Satoru Mitomo, Toru Naganuma, Yusuke Fujino, Hiroyoshi Kawamoto, Sandeep Basavarajaiah, Michael Pitt, Wei-Hsian Yin, Damras Tresukosol, Antonio Colombo, Sunao Nakamura
BACKGROUND: There are only limited studies reporting clinical outcomes after bioresorbable vascular scaffold (BVS; Absorb; Abbott Vascular, Santa Clara, CA) implantation for coronary chronic total occlusions (CTO). The aim of this study was to evaluate the real-world feasibility and safety of BVS implantation for the treatment of CTO. METHODS AND RESULTS: We retrospectively evaluated CTO cases treated with BVS from a multicenter registry. The primary end point was target lesion failure defined as a composite of cardiac death, target vessel myocardial infarction, and clinically driven target lesion revascularization...
January 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28069383/transgenic-rnai-of-bmreepa-in-silkworms-can-enhance-the-resistance-of-silkworm-to-bombyxmori-nucleopolyhedrovirus
#5
Xiao-Long Dong, Tai-Hang Liu, Wei Wang, Cai-Xia Pan, Guo-Yu Du, Yun-Fei Wu, Malavika Adur, Min-Juan Zhang, Min-Hui Pan, Cheng Lu
Our previous study has identified a gene, BmREEPa, which affects BmNPV invasion in silkworm cells. In this study, we interfered with BmREEPa in silkworm larvae through transgenic technology and screened BmREEPa-RNAi silkworm strains (RP). We found the mortality in RP was lower than that in Dazao, when silkworm larvae were infected with BmNPV via oral and injection routes. And the expression level of VP39 was lower in RP than in Dazao in the group infected via injection. In the oral infection group, VP39 expression level showed significant reduction at 48 h post-infection...
January 6, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28069258/reference-values-for-human-posture-measurements-based-on-computerized-photogrammetry-a-systematic-review
#6
Ana Freire Macedo Ribeiro, Anke Bergmann, Thiago Lemos, Antônio Guilherme Pacheco, Maitê Mello Russo, Laura Alice Santos de Oliveira, Erika de Carvalho Rodrigues
OBJECTIVE: The main objective of this study was to review the literature to identify reference values for angles and distances of body segments related to upright posture in healthy adult women with the Postural Assessment Software (PAS/SAPO). METHODS: Electronic databases (BVS, PubMed, SciELO and Scopus) were assessed using the following descriptors: evaluation, posture, photogrammetry, physical therapy, postural alignment, postural assessment, and physiotherapy...
January 6, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28067196/management-of-st-elevation-myocardial-infarction-in-young-patients-by-limiting-implantation-of-durable-intracoronary-devices-and-guided-by-optical-frequency-domain-imaging-proof-of-concept-study
#7
Nicolas Combaret, Géraud Souteyrand, Nicolas Barber-Chamoux, Guilhem Malcles, Aimé Amonchot, Bruno Pereira, Louis Le Bivic, Romain Eschalier, Romain Trésorier, Pascal Motreff
AIMS: To demonstrate the feasibility and safety of ST-elevation myocardial infarction (STEMI) management in young patients by limiting implantation of durable intracoronary devices (using bioresorbable stent or medical treatment alone). METHODS AND RESULTS: Patients <50 years admitted for STEMI with single vessel disease received a two-stage management strategy. During a second coronary angiography performed between day 2 and day 7, optical frequency domain imaging (OFDI) enabled to guide therapeutic management: i) in the case of a stenosis greater that 70% or plaque prolapse, implantation of a BVS; ii) in the other cases, continuation of medical management alone without stenting...
January 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28062867/guide-wire-a-sisted-cannulation-versus-conventional-contrast-to-prevent-pancreatitis-a-systematic-review-and-meta-analysis-based-on-randomized-control-trials
#8
Eduardo T de Moura, Eduardo G de Moura, Wanderley Bernardo, Spencer Cheng, Andre Kondo, Diogo T de Moura, Jose Bravo, Everson L Artifon
OBJECTIVE: Through this systematic review and meta-analysis, we aim to clarify the differences between these two techniques, thus improving primary success cannulation and reducing complications during endoscopic retrograde cholangiopancreatography, primarily pancreatitis. METHODS: A comprehensive search was conducted to search for data available up until June2015from the most important databases available in the health field: EMBASE, MEDLINE (via PubMed), Cochrane, LILACS and CENTRAL (via BVS), SCOPUS, the CAPES database (Brazil), and gray literature...
October 2016: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28057284/very-late-scaffold-thrombosis-of-bioresorbable-vascular-scaffold-systematic-review-and%C3%A2-a%C3%A2-meta-analysis
#9
Toshiaki Toyota, Takeshi Morimoto, Hiroki Shiomi, Yusuke Yoshikawa, Hidenori Yaku, Yugo Yamashita, Takeshi Kimura
OBJECTIVES: This study sought to compare the 2-year outcomes between bioresorbable vascular scaffold (BVS) and everolimus-eluting metallic drug-eluting stent (EES). BACKGROUND: The occurrence of very late stent/scaffold thrombosis (VLST) of BVS beyond 1 year after implantation is an increasing concern. METHODS: We conducted a meta-analysis of 24 studies (BVS: n = 2,567 and EES: n = 19,806) reporting the 2-year outcomes of BVS and/or EES to compare the risk of BVS versus EES for stent/scaffold thrombosis (ST) and target lesion failure (TLF) in 7 comparative studies (3 randomized and 4 observational), and to estimate the pooled incidence rates of ST and TLF including additional 17 single-arm studies...
January 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28045410/clinical-and-angiographic-outcomes-at-more-than-1-year-after-treatment-of-chronic-total-occlusions-with-the-everolimus-eluting-bioresorbable-vascular-scaffold
#10
Aylin Hatice Yamaç, Abdülkadir Yıldız, Meherrem Nasifov, Ahmet Taştan, Nemat Bashirov, Ömer Göktekin
OBJECTIVE: Treatment of chronic total occlusion (CTO) with everolimus-eluting bioresorbable vascular scaffold (BVS) is safe and effective at short-term follow-up (FU). The current study investigated clinical and angiographic outcomes after treatment of CTO with BVS at >1 year. METHODS: Thirty patients who underwent successful recanalization of 35 CTOs were included in this study. Quantitative coronary angiography (QCA) was performed at median FU period of 402 days...
December 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28038806/bioresorbable-coronary-stent-for-the-treatment-of-complex-coronary-lesions-data-from-an-all-comer-registry
#11
Andrea Cuculo, Antonio Ruggiero, Antonio Centola, Giulio Campanale, Tommaso Passero, Antonio Gaglione, Matteo Di Biase, Natale Daniele Brunetti
BACKGROUND: The study aimed to report the results from an all-comers registry of patients undergoing coronary angioplasty and treated with bioresorbable vascular scaffold (BVS). METHODS: Fifty-five consecutive patients with type B/C coronary lesions according to the AHA classification and treated with BVS were enrolled in the study. The clinical and procedural characteristics of enrolled patients were recorded. Fifty-five consecutive subjects with coronary lesions type B/C treated with everolimus eluting stent (EES) were used as control group...
December 19, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28017311/efficacy-and-safety-of-the-absorb-everolimus-eluting-bioresorbable-scaffold%C3%A2-for-treatment-of-patients%C3%A2-with%C3%A2-diabetes-mellitus-results-of-the-absorb-diabetic-substudy
#12
Dean J Kereiakes, Stephen G Ellis, Takeshi Kimura, Alexandre Abizaid, Weiying Zhao, Susan Veldhof, Minh-Thien Vu, Zhen Zhang, Yoshinobu Onuma, Bernard Chevalier, Patrick W Serruys, Gregg W Stone
OBJECTIVES: The study sought to evaluate the efficacy and safety of the Absorb everolimus-eluting bioresorbable vascular scaffold (BVS) (Abbott Vascular, Abbott Park, Illinois) in patients with diabetes mellitus. BACKGROUND: Randomized, controlled trials have demonstrated comparable clinical outcomes following percutaneous coronary intervention with either Absorb BVS or metallic Xience everolimus-eluting stent. However, these trials lack power required to provide reliable treatment effect estimates in this high-risk population...
December 1, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28013076/sorption-and-degradation-of-phthalate-esters-by-a-novel-functional-hyper-cross-linked-polymer
#13
Jing Shi, Fei Li, Danyang Yin, Zhengwen Xu, Ling Cheng
A novel functional hyper-cross-linked polymer (NFHP) modified with trimethylamine was prepared. NFHP was characterized by FTIR, XPS, XRD, SEM and Micromeritics ASAP-2010 automatic surface area analysis instrument. Adsorption and hydrolysis degradation of phthalate acid esters (PAEs) by NFHP were also investigated as a function of temperature, equilibrium concentration and PAEs types. Results indicated that NFHP could adsorb and catalyze hydrolysis of PAEs simultaneously. There was a positive relationship between the removal capacity and temperature, equilibrium concentration, and PAEs hydrophobicity...
December 10, 2016: Chemosphere
https://www.readbyqxmd.com/read/28012050/comparative-assessment-of-plaque-media-change-on-three-modalities-of-ivus-immediately-after-implantation-of-either-everolimus-eluting-bioresorbable-vascular-scaffold-or-everolimus-eluting-metallic-stent-in-absorb-ii-study
#14
Yaping Zeng, Rafael Cavalcante, Erhan Tenekecioglu, Pannipa Suwannasom, Yohei Sotomi, Carlos Collet, Mahammad Abdelghani, Hans Jonker, Franck Digne, Dieter Horstkotte, Manfred Zehender, Ciro Indolfi, Francesco Saia, Rosario Fiorilli, Bernard Chevalier, Leonardo Bolognese, Javier Goicolea, Shaoping Nie, Yoshinobu Onuma, Patrick W Serruys
The purpose of the study to assess the comparability of immediate changes in plaque/media volume (PV) on three modalities of intravascular ultrasound (IVUS) after implantation of either bioresorbable vascular scaffold (BVS) or everolimus-eluting metallic stent (EES) in Absorb II Study. The two devices have different device volume and ultrasound backscattering that may interfere with the "plaque/media" assessed by three modalities on IVUS: grayscale, backscattering of radiofrequency and brightness function. In a multicenter randomized controlled trial, 501 patients with stable or unstable angina underwent documentary IVUS pre- and post- implantation...
December 23, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27998840/quantification-and-characterisation-of-released-plaque-material-during-bioresorbable-vascular-scaffold-implantation-into-right-coronary-artery-lesions-by-multimodality-intracoronary-imaging
#15
Heike A Hildebrandt, Polykarpos C Patsalis, Fadi Al-Rashid, Markus Neuhäuser, Tienush Rassaf, Gerd Heusch, Philipp Kahlert, Petra Kleinbongard
AIMS: We aimed to compare intravascular ultrasound with virtual histology (VH-IVUS), optical coherence tomography (OCT) and near-infrared spectroscopy (NIRS) for their ability to quantify the true amount and characterise the nature of released plaque material during bioresorbable vascular scaffold (BVS) implantation into right coronary artery (RCA) lesions using a distal occlusion and aspiration device. METHODS AND RESULTS: Seventeen patients underwent BVS implantation into the right coronary artery under distal protection with intracoronary imaging using VH-IVUS, OCT and NIRS...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27993756/change-in-lumen-eccentricity-and-asymmetry-after-treatment-with-absorb-bioresorbable-vascular-scaffolds-in-the-absorb-cohort-b-trial-a-five-year-serial-optical-coherence-tomography-imaging-study
#16
Pannipa Suwannasom, Yohei Sotomi, Taku Asano, Jaryl Ng Chen Koon, Hiroki Tateishi, Yaping Zeng, Erhan Tenekecioglu, Joanna J Wykrzykowska, Nicolas Foin, Robert J de Winter, John A Ormiston, Patrick W Serruys, Yoshinobu Onuma
AIMS: To investigate long-term changes in lumen eccentricity and asymmetry at 5 years after implantation of the bioresorbable vascular scaffold (BVS). METHODS AND RESULTS: Out of 101 patients from Absorb cohort B trial, 28 patients(29 lesions) with serial Optical Coherence Tomography(OCT) examination at 4 different time points(Cohort B1: post-procedure,6 months, 2, and 5 years[n=13]; Cohort B2:post-procedure,1, 3, and 5 years[n=16]) were evaluated. The longitudinal variance in lumen diameter was assessed by asymmetry index(AI)...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27982363/-efficiency-indicators-to-assess-the-organ-donation-and-transplantation-process-systematic-review-of-the-literature
#17
Marina Martins Siqueira, Claudia Affonso Araujo, Bartira de Aguiar Roza, Janine Schirmer
Objective: To search the literature and identify indicators used to monitor and control the organ donation and transplantation process and to group these indicators into categories. Method: In November 2014, a systematic review of the literature was carried out in the following databases: Biblioteca Virtual em Saúde (BVS), EBSCO, Emerald, Proquest, Science Direct, and Web of Science. The following search terms (and the corresponding terms in Brazilian Portuguese) were employed: "efficiency," "indicators," "organ donation," "tissue and organ procurement," and "organ transplantation...
August 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/27970221/tct-830-difference-in-hemodynamic-micro-environment-in-vessels-scaffolded-with-absorb-bvs-or-mirage-microfiber-sirolimus-eluting-scaffold-a-pre-clinical-study-of-endothelial-shear-stress
#18
Erhan Tenekecioglu, Ryo Torii, Christos Bourantas, Rafael Cavalcante, Yohei Sotomi, Yaping Zeng, Tom Crake, Alexandre Abizaid, Yoshinobu Onuma, Teguh Santoso, Patrick Serruys
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969986/tct-60-1-year-clinical-outcomes-of-absorb-bioresorbable-vascular-scaffold-bvs-in-diabetic-and-non-diabetic-patients-patient-level-pooled-analysis-from-the-absorb-randomized-trials
#19
Ariel Furer, Ori Ben-Yehuda, Bjorn Redfors, Patrick Serruys, Runlin Gao, Takeshi Kimura, Dean Kereiakes, Stephen Ellis, Weiying Zhao, Minh-Thien Vu, Yoshinobu Onuma, Gregg Stone
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969793/tct-440-impact-of-optimal-implantation-technique-on-bioresorbable-scaffold-expansion-and-one-year-clinical-outcomes-in-patients-presenting-with-acute-coronary-syndromes-and-calcified-lesions-a-pooled-analysis-of-bvs-stemi-first-and-bvs-expand-studies
#20
Mariusz Tomaniak, Cordula Felix, Jiang Ming Fam, Robert-Jan van Geuns, Nicolas Van Mieghem, Evelyn Regar, Joost Daemen, Felix Zijlstra, Roberto Diletti
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
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