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https://www.readbyqxmd.com/read/28935081/efficacy-and-safety-of-the-absorb-bioresorbable-vascular-scaffold-in-females-and-males-results-of-an-individual-patient-level-pooled-meta-analysis-of-randomized-controlled-trials
#1
Satya Shreenivas, Dean J Kereiakes, Stephen G Ellis, Runlin Gao, Takeshi Kimura, Yoshinobu Onuma, Karine Piard-Ruster, Yunlong Zhang, Kai Koo, Minh-Thien Vu, Patrick W Serruys, Gregg W Stone
OBJECTIVES: Because females are under-represented in coronary trials, this study sought to assess the relative safety and efficacy of Absorb bioresorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, California) and the Xience everolimus-eluting stent in females compared with males. BACKGROUND: The Absorb everolimus-eluting BVS provides drug delivery and mechanical support similar to a metallic drug-eluting stent, followed by resorption and restoration of more normal vascular structure with the potential to improve late clinical outcomes...
September 25, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28935080/no-trofi-for-routine-post-dilatation-after%C3%A2-bvs-implantation
#2
EDITORIAL
Tom Adriaenssens, Peter R Sinnaeve
No abstract text is available yet for this article.
September 25, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28935077/a-prospective-evaluation-of-a-pre-specified-absorb-bvs-implantation-strategy-in-st-segment-elevation-myocardial-infarction-the-bvs-stemi-strategy-it-study
#3
Alfonso Ielasi, Gianluca Campo, Claudio Rapetto, Attilio Varricchio, Bernardo Cortese, Salvatore Brugaletta, Salvatore Geraci, Paolo Vicinelli, Fortunato Scotto di Uccio, Gioel Gabrio Secco, Arnaldo Poli, Elisa Nicolini, Kohki Ishida, Azeem Latib, Maurizio Tespili
OBJECTIVES: The aim of this study was to assess the feasibility and clinical results following a pre-specified bioresorbable scaffold (Absorb BVS) implantation strategy in patients with ST-segment elevation myocardial infarction (STEMI). BACKGROUND: Concerns were raised about the safety of Absorb because a non-negligible rate of thrombosis was reported within 30 days and at midterm follow-up after primary percutaneous coronary intervention. METHODS: This was a prospective, multicenter study of patients with STEMI (<75 years of age with symptom onset <12 h) undergoing primary percutaneous coronary intervention with Absorb following a dedicated implantation protocol...
September 25, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28934083/outpatient-vaginal-hysterectomy-comparison-of-conventional-suture-ligature-versus-electrosurgical-bipolar-vessel-sealing
#4
G Giraudet, J P Lucot, F Sanz, C Rubod, P Collinet, M Cosson
OBJECTIVE: The aim of our study was to evaluate the feasibility of vaginal hysterectomy in an ambulatory care system and the best way to perform it between conventional and bipolar vessel sealing system ligatures. PATIENTS AND METHODS: This was a prospective study of 32 patients with vaginal hysterectomy at Lille University Hospital between December 2013 and May 2015. Two surgical techniques were compared: conventional suture ligature (CSL) and electrosurgical bipolar vessel sealing (BVS)...
May 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/28930718/estimating-usual-intake-in-the-2nd-bavarian-food-consumption-survey-comparison-of-the-results-derived-by-the-national-cancer-institute-method-and-a-basic-individual-means-approach
#5
Nina Wawro, Christina Kleiser, Stephanie Himmerich, Kurt Gedrich, Heiner Boeing, Sven Knueppel, Jakob Linseisen
BACKGROUND: The valid estimation of the usual dietary intake remains a challenge till date. We applied the method suggested by the National Cancer Institute (NCI) to data from the 2nd Bavarian Food Consumption Survey (BVS II) and compared it to an individual means approach. METHODS: Within the cross-sectional BVS II, 1,050 Bavarian residents aged 13-80 years participated in a personal interview and completed three 24-h dietary recalls by telephone interview. For the 13 main food groups and 23 subgroups the usual intake was calculated by (1) an individual means approach and (2) by the NCI method...
September 21, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28918876/evaluation-of-potential-substrates-for-restenosis-and-thrombosis-in-overlapped-versus-edge-to-edge-juxtaposed-bioabsorbable-scaffolds-insights-from-a-computed-fluid-dynamic-study
#6
Gianluca Rigatelli, Marco Zuin, Fabio Dell'Avvocata, Paolo Cardaioli, Dobrin Vassiliev, Miroslaw Ferenc, Nguyen Tuan Nghia, Thach Nguyen, Nicholas Foin
BACKGROUND/PURPOSE: Multiple BRSs and specifically the Absorb scaffold (BVS) (Abbott Vascular, Santa Clara, CA USA) have been often used to treat long diffuse coronary artery lesions. We evaluate by a computational fluid dynamic(CFD) study the impact on the intravascular fluid rheology on multiple bioabsorbable scaffolds (BRS) by standard overlapping versus edge-to-edge technique. METHODS/MATERIALS: We simulated the treatment of a real long significant coronary lesion (>70% luminal narrowing) involving the left anterior descending artery (LAD) treated with a standard or edge-to-edge technique, respectively...
August 17, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28913627/everolimus-eluting-bioresorbable-vascular-scaffold-in-daily-clinical-practice-a%C3%A2-single-centre-experience
#7
W S Remkes, R S Hermanides, M W Kennedy, E Fabris, E Kaplan, J P Ottervanger, A W J van 't Hof, E Kedhi
BACKGROUND: Recent evidence has raised concerns regarding the safety of the everolimus-eluting bioresorbable vascular scaffold (E-BVS) (Absorb, Abbott Vascular, Santa Clara, CA, USA). Following these data, the use of this device has diminished in the Netherlands; however, daily practice data are limited. Therefore we studied the incidence of safety and efficacy outcomes with this device in daily clinical practice in a single large tertiary centre in the Netherlands. METHODS: All E‑BVS treated patients were included in this analysis...
September 14, 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/28904203/three-conserved-regions-in-baculovirus-sulfhydryl-oxidase-p33-are-critical-for-enzymatic-activity-and-function
#8
Wenhua Kuang, Huanyu Zhang, Manli Wang, Ning-Yi Zhou, Fei Deng, Hualin Wang, Peng Gong, Zhihong Hu
Baculoviruses encode a conserved sulfhydryl oxidase P33, which is necessary for budded virus (BV) production and multi-nucleocapsid occlusion-derived virus (ODV) formation. Here, the structural and functional relationship of P33 was revealed by X-ray crystallography, site-directed mutagenesis, and functional analysis. Based on crystallographic characterization and structural analysis, a series of P33 mutants within three conserved regions, i.e. the active site, dimer interface, and the R127-E183 salt bridge, were constructed...
September 13, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28898243/neoatherosclerosis-development-following-bioresorbable-vascular-scaffold-implantation-in-diabetic-and-non-diabetic-swine
#9
Nienke S van Ditzhuijzen, Mie Kurata, Mieke van den Heuvel, Oana Sorop, Richard W B van Duin, Ilona Krabbendam-Peters, Jurgen Ligthart, Karen Witberg, Magdalena Murawska, Brett Bouma, Martin Villiger, Hector M Garcia-Garcia, Patrick W Serruys, Felix Zijlstra, Gijs van Soest, Dirk-Jan Duncker, Evelyn Regar, Heleen M M van Beusekom
BACKGROUND: DM remains a risk factor for poor outcome after stent-implantation, but little is known if and how DM affects the vascular response to BVS. AIM: The aim of our study was to examine coronary responses to bioresorbable vascular scaffolds (BVS) in swine with and without diabetes mellitus fed a 'fast-food' diet (FF-DM and FF-NDM, respectively) by sequential optical coherence tomography (OCT)-imaging and histology. METHODS: Fifteen male swine were evaluated...
2017: PloS One
https://www.readbyqxmd.com/read/28894599/occurrence-and-management-of-bioresorbable-vascular-scaffold-failure-in-real-life-studies
#10
REVIEW
Bernardo Cortese, Mostafa Elwany
Bioresorbable vascular scaffold (BVS) has emerged as a new technology aiming at overcoming some drawbacks of the conventional metallic stent. In spite of the initial promising results, this technology stumbled upon numerous challenges, which were revealed in the real world studies. Thanks to real world trials and registries findings, our knowledge about the BVS has grown over time, thus we have understood on BVS behavior in various settings and formulated better implantation techniques. In this article, we will review the incidence of BVS failure in real world studies, its different etiologies and management strategies...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28894597/brs-implantation-in-long-lesions-requiring-device-overlapping-myth-or-reality
#11
REVIEW
Simone Biscaglia, Andrea Erriquez, Davide Bernucci, Giulia Bugani, Enrico Favaretto, Gianluca Campo
Dealing with bioresorbable vascular scaffolds (BVS) implantation in long lesions requiring device overlapping in this particular moment might seem a little provocative for several reasons. First, most studies testing BVS have focused on their safety and efficacy profile in simple patients with simple lesions. Second, ABSORB II did not meet its primary endpoint, while ABSORB III showed a higher rate of target vessel-myocardial infarction (TV-MI) at 2 years. Third, data on porcine model showed that overlapping zone has delayed but greater neointimal proliferation with consequent higher risk for scaffold thrombosis in the short-term and of in-scaffold restenosis in the long-term...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28894595/the-impact-of-the-3-year-absorb-ii-trial-results-on-my-clinical-practice-an-italian-survey
#12
Matteo Serenelli, Simone Biscaglia, Elisabetta Tonet, Arnaldo Poli, Elisa Nicolini, Alfonso Ielasi, Andrea Erriquez, Gianluca Campo
BACKGROUND: To evaluate how the 3-year results from the "A clinical evaluation to compare the safety, efficacy and performance of ABSORB everolimus eluting bioresorbable vascular scaffold (BVS) system against XIENCE everolimus eluting coronary stent system in the treatment of subjects with ischemic heart disease caused by de novo native coronary artery lesions" (ABSORB II) trial have influenced clinical practice among Italian interventional cardiologists. METHODS: We performed a survey among 95 interventional cardiologists sending a brief questionnaire by electronic mail...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28894594/effectiveness-and-safety-of-the-absorb-bioresorbable-vascular-scaffold-for-the-treatment-of-coronary-artery-disease-systematic-review-and-meta-analysis-of-randomized-clinical-trials
#13
Rita Pavasini, Matteo Serenelli, Francesco Gallo, Giulia Bugani, Salvatore Geraci, Paolo Vicinelli, Gianluca Campo
BACKGROUND: In the last years bioresorbable vascular scaffold (BVS) become a new therapeutic option for interventional cardiologists, with the advantage of a scaffold inducing a possible vessel wall restoration. Nevertheless, several trials tried to prove the safety and efficacy profile of scaffolds, but with conflicting results. METHODS: A systematic review and meta-analysis was performed. The search was carried out in PubMed, Google Scholar, Biomed Central and Cochrane Library between January and March 2017...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28888665/fish-scale-derived-collagen-patch-promotes-growth-of-blood-and-lymphatic-vessels-in-vivo
#14
Jun Kit Wang, Kim Pin Yeo, Yong Yao Chun, Timothy Thatt Yang Tan, Nguan Soon Tan, Véronique Angeli, Cleo Choong
In this study, Type I collagen was extracted from fish scales as a potential alternative source of collagen for tissue engineering applications. Since unmodified collagen typically has poor mechanical and degradation stability both in vitro and in vivo, additional methylation modification and 1,4-butanediol diglycidyl ether (BDE) crosslinking steps were used to improve the physicochemical properties of fish scale-derived collagen. Subsequently, in vivo studies using a murine model demonstrated the biocompatibility of the different fish scale-derived collagen patches...
September 6, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28867010/mid-term-clinical-outcomes-of-absorb-bioresorbable-vascular-scaffold-versus-everolimus-eluting-stent-for-coronary-bifurcation-lesions
#15
Toru Naganuma, Hiroyoshi Kawamoto, Vasileios F Panoulas, Azeem Latib, Akihito Tanaka, Satoru Mitomo, Neil Ruparelia, Richard J Jabbour, Alaide Chieffo, Mauro Carlino, Matteo Montorfano, Antonio Colombo
BACKGROUND: Data regarding bioresorbable vascular scaffolds (BVS) use in coronary bifurcation lesions are limited. The aim of this study was to compare mid-term clinical outcomes of all-comer patients treated with BVS versus everolimus-eluting stents (EES) for bifurcation lesions. METHODS: A total of 351 non-left-main bifurcation lesions in 323 all-comer patients were treated either with BVS (166 bifurcations in 147 patients) or EES (185 bifurcations in 176 patients)...
November 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28866037/very-late-restenosis-of-a-bvs-implanted-in%C3%A2-a-degenerated-saphenous-vein-graft
#16
Juan Gabriel Córdoba-Soriano, Antonio Gutiérrez-Díez, Arsenio Gallardo López, Jesús Jiménez-Mazuecos
No abstract text is available yet for this article.
August 24, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28866036/bioresorbable-vascular-scaffolds-for-patients-with-in-stent-restenosis-the-ribs-vi-study
#17
Fernando Alfonso, Javier Cuesta, María José Pérez-Vizcayno, Bruno García Del Blanco, José Ramón Rumoroso, Francisco Bosa, Armando Pérez de Prado, Mónica Masotti, Raul Moreno, Angel Cequier, Hipólito Gutiérrez, Arturo García Touchard, José Ramón López-Mínguez, Javier Zueco, Vicens Martí, Maite Velázquez, César Morís, Teresa Bastante, Marcos García-Guimaraes, Fernando Rivero, Cristina Fernández
OBJECTIVES: This study sought to assess the value of bioresorbable vascular scaffolds (BVS) in patients with in-stent restenosis (ISR). BACKGROUND: Currently both drug-eluting stents (DES) and drug-eluting balloons (DEB) are recommended in patients with ISR. However, the value of BVS in this setting remains unclear. METHODS: RIBS VI was a prospective multicenter study (19 Spanish sites) that included 141 patients treated with BVS for either bare-metal stent (BMS) ISR or DES-ISR...
August 24, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28853189/clinical-and-angiographic-outcome-of-a-single-center-real-world-population-treated-with-a-dedicated-technique-of-implantation-for-bioresorbable-vascular-scaffolds-the-fatebenefratelli-bioresorbable-vascular-scaffold-fabs-registry
#18
Bernardo Cortese, Gaetano di Palma, Gregory Dendramis, Enrico Cerrato, Roberto A Latini, Mostafa Elwany, Pedro S Orrego, Romano G Seregni
OBJECTIVES: With this prospective study we aim at investigating the long-term outcome of a consecutive cohort of patients successfully treated with bioresorbable scaffold (BVS) implantation. BACKGROUND: It is not clearly understood if there is a relation between the technique of BVS implantation and the outcome. METHODS: Between December 2012 and December 2014, all consecutive patients treated with BVS were included in this registry and received an angiographic follow-up...
August 29, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28845861/-hybrid-percutaneous-coronary-intervention-with-drug-eluting-stent-in-combination-with-bioresorbable-vascular-scaffolds-for-complex-coronary-lesions
#19
Massimo Fineschi, Arcangelo Carrera, Carlo Pierli
Drug-eluting stents (DES) have significantly improved the outcome of percutaneous coronary intervention (PCI); however, several concerns remain regarding late adverse events associated with the presence of a permanent rigid metallic cage that might impair the natural healing process of the coronary vessel wall. Recently, PCI with bioresorbable vascular scaffolds (BVS) has emerged as an interesting alternative with several potential advantages related to the complete resorption process that occurs within 3-5 years...
September 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/28829745/everolimus-eluting-bioresorbable-scaffolds-in-patients-with-coronary-artery-disease-results-from-the-german-austrian-absorb-registry-gabi-r
#20
Holger M Nef, Jens Wiebe, Johannes Kastner, Julinda Mehilli, Thomas Münzel, Christoph Naber, Till Neumann, Gert Richardt, Axel Schmermund, Jochen Wöhrle, Ralf Zahn, Thomas Riemer, Stephan Achenbach, Christian W Hamm
AIMS: To analyze procedural results and mid-term safety of everolimus-eluting bioresorbable vascular scaffolds (BVS) used for percutaneous coronary intervention in a large all-comer cohort from the German-Austrian ABSORB Registry (GABI-R). METHODS AND RESULTS: A total of 3231 patients were included in this prospective, observational, multicentre study (Clinicaltrial.gov NCT02066623) of consecutive patients undergoing BVS implantation between November 2013 and January 2016...
August 22, 2017: EuroIntervention
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