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Oral rehydration therapy

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https://www.readbyqxmd.com/read/28893243/impact-of-pharmacy-worker-training-and-deployment-on-access-to-essential-medicines-for-children-under-five-in-malawi-a-cluster-quasi-experimental-evaluation
#1
Joseph B Babigumira, Solomon J Lubinga, Alisa M Jenny, Erin Larsen-Cooper, Jessica Crawford, Charles Matemba, Andy Stergachis
BACKGROUND: Poor access to essential medicines is common in many low- and middle-income countries, partly due to an insufficient and inadequately trained workforce to manage the medicines supply chain. We conducted a prospective impact evaluation of the training and deployment of pharmacy assistants (PAs) to rural health centers in Malawi. METHODS: A quasi-experimental design was used to compare access to medicines in two districts where newly trained PAs were deployed to health centers (intervention) and two districts with no trained PAs at health centers (comparison)...
September 11, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28882877/clinical-pathway-produces-sustained-improvement-in-acute-gastroenteritis-care
#2
Lori Rutman, Eileen J Klein, Julie C Brown
BACKGROUND AND OBJECTIVES: Despite widespread use of the rotavirus vaccine in the last decade, dehydrating illnesses impact almost 2 billion children worldwide annually. Evidence supports oral rehydration therapy as a first-line treatment of mild to moderate dehydration. Ondansetron has proven to be a safe and effective adjunct in children with vomiting. We implemented a clinical pathway in our pediatric emergency department (ED) in January 2005 to improve care for this common condition...
September 7, 2017: Pediatrics
https://www.readbyqxmd.com/read/28851766/modelling-the-cost-of-community-interventions-to-reduce-child-mortality-in-south-africa-using-the-lives-saved-tool-list
#3
Lungiswa Ll Nkonki, Lumbwe L Chola, Aviva A Tugendhaft, Karen K Hofman
OBJECTIVE: To estimate the costs and impact on reducing child mortality of scaling up interventions that can be delivered by community health workers at community level from a provider's perspective. SETTING: In this study, we used the Lives Saved Tool (LiST), a module in the spectrum software. Within the spectrum software, LiST interacts with other modules, the AIDS Impact Module, Family Planning Module and Demography Projections Module (Dem Proj), to model the impact of more than 60 interventions that affect cause-specific mortality...
August 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/28835355/efficacy-of-lactobacillus-reuteri-dsm-17938-for-the-treatment-of-acute-gastroenteritis-in-children-protocol-of-a-randomized-controlled-trial
#4
Henryk Szymański, Hania Szajewska
BACKGROUND: Acute gastroenteritis (AGE) is one of the most common diseases among children. Oral rehydration therapy is the key treatment. However, despite proven efficacy, it remains underused. This is because oral rehydration solution neither reduces the frequency of bowel movements and fluid loss nor shortens the duration of illness. Hence, there is interest in adjunctive treatments. According to the 2014 guidelines developed by the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, the use of the following probiotics may be considered in the management of children with AGE in addition to rehydration therapy: Lactobacillus rhamnosus GG (low quality of evidence; strong recommendation) and Saccharomyces boulardii (low quality of evidence; strong recommendation)...
August 23, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28678057/hyaluronidase-assisted-resuscitation-in-kenya-for-severely-dehydrated-children
#5
Hijab Zubairi, Brett D Nelson, Priyanka Tulshian, Karla Fredricks, Zaid Altawil, Sarah Mireles, Fred Odongo, Thomas F Burke
BACKGROUND: Dehydration, mainly due to diarrheal illnesses, is a leading cause of childhood mortality worldwide. Intravenous (IV) therapy is the standard of care for patients who were unable to tolerate oral rehydration; however, placing IVs in fragile, dehydrated veins can be challenging. Studies in resource-rich settings comparing hyaluronidase-assisted subcutaneous rehydration with standard IV rehydration in children have demonstrated several benefits of subcutaneous rehydration, including time and success of line placement, ease of use, satisfaction, and cost-effectiveness...
July 4, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28675983/fluid-supplementation-in-management-of-neonatal-hyperbilirubinemia-a-randomized-controlled-trial
#6
Prachi Goyal, Akshay Mehta, Jasbinder Kaur, Suksham Jain, Vishal Guglani, Deepak Chawla
OBJECTIVE: To evaluate the efficacy of oral or intravenous fluid supplementation in accelerating the decline of serum bilirubin with intensive phototherapy among healthy term and late preterm neonates with hyperbilirubinemia. STUDY DESIGN: This open-label randomized controlled trial randomized neonates with severe hyperbilirubinemia (serum total bilirubin ≥18 mg/dL or within 2 mg/dL of threshold for exchange transfusion) to receive 50 mL/kg of intravenous fluid over 8 h (IVF group, n = 51), 50 mL of oral rehydration solution over 8 h (oral rehydration solution (ORS) group, n = 50) or only standard therapy (control group, n = 49)...
July 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28603456/cost-effectiveness-analysis-of-the-diarrhea-alleviation-through-zinc-and-oral-rehydration-therapy-dazt-program-in-rural-gujarat-india-an-application-of-the-net-benefit-regression-framework
#7
Samuel D Shillcutt, Amnesty E LeFevre, Christa L Fischer-Walker, Sunita Taneja, Robert E Black, Sarmila Mazumder
BACKGROUND: This study evaluates the cost-effectiveness of the DAZT program for scaling up treatment of acute child diarrhea in Gujarat India using a net-benefit regression framework. METHODS: Costs were calculated from societal and caregivers' perspectives and effectiveness was assessed in terms of coverage of zinc and both zinc and Oral Rehydration Salt. Regression models were tested in simple linear regression, with a specified set of covariates, and with a specified set of covariates and interaction terms using linear regression with endogenous treatment effects was used as the reference case...
2017: Cost Effectiveness and Resource Allocation: C/E
https://www.readbyqxmd.com/read/28551933/-recommendations-for-the-diagnosis-and-management-of-pediatric-acute-gastroenteritis-in-israel-update-2017
#8
Firas Rinawi, Shai Ashkenazi, Michael Wilschanski, Eli Somekh, Raanan Shamir
AIMS: The aim of these guidelines is to update and extend evidence-based recommendations for the diagnosis and management of children with acute gastroenteritis (AGE) in Israel, based on new data and the recently published European update. METHODS: The recommendations, which are based on a systematic review of the literature, were graded by the level of evidence. The guidelines were endorsed by the Israeli societies for Pediatric Gastroenterology, Pediatric Infectious Diseases and the Israeli Association of Pediatrics...
March 2017: Harefuah
https://www.readbyqxmd.com/read/28526222/hemocytometric-measures-predict-the-efficacy-of-oral-rehydration-for-children-with-postural-tachycardia-syndrome
#9
Wenxin Lu, Hui Yan, Shu Wu, Wenrui Xu, Hongfang Jin, Junbao Du
OBJECTIVE: To explore whether hemocytometric measures could be qualified predictors for the effect of oral rehydration salts (ORS) in children with postural tachycardia syndrome (POTS). STUDY DESIGN: Thirty-five children with POTS and 29 healthy children were enrolled. General information, hemodynamic status, and baseline hemocytometric variables were collected. Children with POTS received ORS therapy and were followed up for 3 months. The independent risk factors of developing POTS were explored...
May 16, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28452274/an-innovative-approach-to-hydration-for-a-patient-with-dementia
#10
Adam Beales
Nursing older people in acute settings involves the provision of complex care, including the maintenance of good hydration. Dehydration is a serious condition that may contribute to the development of pressure ulcers, urinary tract infections, acute kidney injury and venous thromboembolism. If oral hydration methods are not successful, the alternatives are intravenous (IV) or subcutaneous fluid hydration therapy. These are invasive methods and may not be tolerated by all patients. This article uses a case study to explore an innovative approach to oral hydration...
April 28, 2017: Nursing Older People
https://www.readbyqxmd.com/read/28444008/from-guidelines-to-local-realities-evaluation-of-oral-rehydration-therapy-and-zinc-supplementation-in-guatemala
#11
Rachel Hall-Clifford, Roxanne Amerson
Objective: Diarrhea remains a leading cause of morbidity and mortality for children in low- and middle-income countries throughout the Americas. The World Health Organization (WHO) has developed guidelines on incorporating zinc supplementation (ZS) with traditional oral rehydration therapy (ORT) in order to shorten the duration of diarrheal episodes and to reduce poor health outcomes. Guatemala adopted these guidelines in 2011, but they have not yet been fully implemented at the community level...
April 20, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28439845/a-systematic-review-of-the-clinical-presentation-diagnosis-and-treatment-of-small-bowel-obstruction
#12
REVIEW
Srinivas R Rami Reddy, Mitchell S Cappell
PURPOSE OF REVIEW: This study aimed to systematically review small bowel obstruction (SBO), focusing on recent changes in diagnosis/therapy. RECENT FINDINGS: SBO incidence is about 350,000/annum in the USA. Etiologies include adhesions (65%), hernias (10%), neoplasms (5%), Crohn's disease (5%), and other (15%). Bowel dilatation occurs proximal to obstruction primarily from swallowed air and secondarily from intraluminal fluid accumulation. Dilatation increases mural tension, decreases mucosal perfusion, causes bacterial proliferation, and decreases mural tensile strength that increases bowel perforation risks...
June 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28416428/-nasogastric-rehydration-for-treating-children-with-gastroenteritis
#13
B Rébeillé-Borgella, C Barbier, R Moussaoui, A Faisant, A-P Michard-Lenoir, A Rubio
INTRODUCTION: When oral rehydration is not feasible, enteral rehydration via the nasogastric route has been the ESPGHAN recommended method of rehydration since 2008, rather than intravenous rehydration (IVR), for children with acute gastroenteritis. However, these recommendations are rarely followed in France. Since 2011, in case of failure of oral rehydration, enteral rehydration has been used as a first-line therapy in the Children's Emergency Department at the Grenoble-Alpes University Hospital...
April 14, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28397130/antidiarrheal-drug-therapy
#14
REVIEW
Lawrence R Schiller
INTRODUCTION: Acute diarrhea often runs a self-limited course and little by way of treatment is needed except for oral rehydration therapy. Chronic diarrhea poses a longer-term problem. If not treatable with specific therapy aimed at the underlying pathophysiology, chronic diarrhea often needs long-term symptomatic therapy. PURPOSE OF REVIEW: This paper aims to examine the options for symptomatic, nonspecific treatment of diarrhea. RECENT FINDINGS: The most frequently used therapies are opiate antidiarrheal drugs...
May 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28390725/comparison-of-a-commercially-available-oral-nutritional-supplement-and-intravenous-fluid-therapy-for-dehydration-in-dairy-calves
#15
Jared D Taylor, Merel Rodenburg, Timothy A Snider
Calf scours is a primary cause of morbidity and mortality in the dairy industry. Effective treatments are needed to minimize death, maximize welfare, and maintain growth and productivity. The objective of this trial was to compare the efficacy of a commercially available nutritional supplement (Diaque, Boehringer-Ingelheim Vetmedica Inc., St. Joseph, MO) and i.v. lactated Ringer's solution (LRS) in rehydrating, preventing acidemia, and correcting electrolyte imbalances in an experimental model for calf scours...
April 5, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28363627/evaluation-of-a-nurse-initiated-acute-gastroenteritis-pathway-in-the-pediatric-emergency-department
#16
Rebecca A Carson, Shawna S Mudd, P Jamil Madati
PROBLEM: Acute gastroenteritis (AGE) is a common illness treated in the emergency department. Delays in initiating rehydration for children with mild or moderate dehydration from AGE can lead to prolonged ED visits and increased resource utilization that do not provide prognostic value or support family-centered care. The purpose of this quality improvement project was to promote early oral rehydration therapy (ORT) for persons with AGE in an attempt to reduce unnecessary resource utilization and length of stay (LOS)...
September 2017: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
https://www.readbyqxmd.com/read/28332578/a-new-class-of-inhibitors-of-the-arac-family-virulence-regulator-vibrio-cholerae-toxt
#17
Anne K Woodbrey, Evans O Onyango, Maria Pellegrini, Gabriela Kovacikova, Ronald K Taylor, Gordon W Gribble, F Jon Kull
Vibrio cholerae is responsible for the diarrheal disease cholera that infects millions of people worldwide. While vaccines protecting against cholera exist, and oral rehydration therapy is an effective treatment method, the disease will remain a global health threat until long-term solutions such as improved sanitation and access to clean water become widely available. Because of this, there is a pressing need for potent therapeutics that can either mitigate cholera symptoms, or act prophylactically to prevent the virulent effects of a cholera infection...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28302312/cholera
#18
REVIEW
John D Clemens, G Balakrish Nair, Tahmeed Ahmed, Firdausi Qadri, Jan Holmgren
Cholera is an acute, watery diarrhoeal disease caused by Vibrio cholerae of the O1 or O139 serogroups. In the past two centuries, cholera has emerged and spread from the Ganges Delta six times and from Indonesia once to cause global pandemics. Rational approaches to the case management of cholera with oral and intravenous rehydration therapy have reduced the case fatality of cholera from more than 50% to much less than 1%. Despite improvements in water quality, sanitation, and hygiene, as well as in the clinical treatment of cholera, the disease is still estimated to cause about 100 000 deaths every year...
March 10, 2017: Lancet
https://www.readbyqxmd.com/read/28285621/antidiarrheal-activity-of-hexane-extract-of-citrus-limon-peel-in-an-experimental-animal-model
#19
Olasupo Stephen Adeniyi, James Omale, Samuel Chukwuma Omeje, Victoria Ojimaojo Edino
OBJECTIVE: Acute diarrhea is one of the major illnesses that cause death in children, despite clinical interventions and the use of oral rehydration therapy. Thus, there is need to discover other effective, affordable and accessible treatments for this disease. Therefore, this study was carried out to investigate the effects of hexane extract of Citrus limon peel (HECLP) on castor oil-induced diarrhea in rats. METHODS: Diarrhea was induced in male albino Wistar rats weighing 100-150 g...
March 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28277412/the-use-of-a-triage-based-protocol-for-oral-rehydration-in-a-pediatric-emergency-department
#20
Marissa A Hendrickson, Jennifer Zaremba, Andrew R Wey, Philippe R Gaillard, Anupam B Kharbanda
BACKGROUND: Guidelines recommend oral rehydration therapy (ORT) and avoidance of laboratory tests and intravenous fluids for mild to moderate dehydration in children with gastroenteritis; oral ondansetron has been shown to be an effective adjunct. OBJECTIVES: The aim of this study was to determine if a triage-based, nurse-initiated protocol for early provision of ondansetron and ORT could safely improve the care of pediatric emergency department (ED) patients with symptoms of gastroenteritis...
March 9, 2017: Pediatric Emergency Care
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