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Oral rehydration therapy

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https://www.readbyqxmd.com/read/27912886/medicinal-plants-and-natural-molecules-with-in-vitro-and-in-vivo-activity-against-rotavirus-a-systematic-review
#1
REVIEW
Gopalsamy Rajiv Gandhi, Paula Gurgel Barreto, Bruno Dos Santos Lima, Jullyana de Souza Siqueira Quintans, Adriano Antunes de Souza Araújo, Narendra Narain, Lucindo Jose Quintans-Júnior, Ricardo Queiroz Gurgel
BACKGROUND: Rotaviruses can cause life-threatening health disorders, such as severe dehydrating gastroenteritis and diarrhea in children. Vaccination is the main preventive strategy to reduce rotavirus diarrhea and the severity of episodes, but vaccines are not fully effective and new episodes may occur, even in vaccinated children. The WHO recommends oral rehydration therapy and zinc supplementation for rotavirus-induced diarrhea management. There is little preclinical evidence to support the use of phytotherapeutics in the management of rotaviral infections...
December 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/27852545/effects-of-zinc-or-synbiotic-on-the-duration-of-diarrhea-in-children-with-acute-infectious-diarrhea
#2
Ahmet Sami Yazar, Şirin Güven, Ener Çağrı Dinleyici
BACKGROUND/AIMS: Probiotic effects on acute infectious diarrhea are strain(s) specific, and all formulations should be evaluated by clinical trials. We aimed to evaluate the effect of a synbiotic preparation on the duration of diarrhea in children compared to a zinc suspension. MATERIALS AND METHODS: We conducted a single-center, randomized, and controlled clinical trial in children with acute infectious diarrhea. The first group received a synbiotic preparation containing Lactobacillus casei, L...
November 2016: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/27816564/community-health-workers-provide-integrated-community-case-management-using-malaria-rapid-diagnostic-test-kits
#3
Bright C Orji, Namratha Rao, Elizabeth Thompson, William R Brieger, Emmanuel 'Dipo Otolorin
BACKGROUND: Throughout Nigeria malaria is an endemic disease. Efforts to treat malaria can also be combined with other illnesses including pneumonia and diarrhea, which are killing children under five years of age. The use of Rapid Diagnostic Test (RDT) aids early diagnosis of malaria and informs when other illnesses should be considered. Those with positive RDT results should be treated with Artemisinin-based Combination Therapy (ACTs), while those with negative RDTs results are further investigated for pneumonia and diarrhea...
October 26, 2016: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/27807452/child-survival-strategies-assessment-of-knowledge-and-practice-of-rural-women-of-reproductive-age-in-cross-river-state-nigeria
#4
Aniekan Jumbo Etokidem, Ofonime Johnson
Introduction. Nigeria is one of the five countries that account for about 50% of under-five mortality in the world. The objective of this study was to assess the knowledge and practice of child survival strategies among rural community caregivers in Cross River State of Nigeria. Materials and Methods. This descriptive cross-sectional survey used a pretested questionnaire to obtain information from 150 women of reproductive age. Data analysis was done using SPSS version 20. Results. The child survival strategy known to most of the respondents was oral rehydration therapy as indicated by 98% followed by female education by 73...
2016: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/27803895/reduced-susceptibility-to-extended-spectrum-%C3%AE-lactams-in-vibrio-cholerae-isolated-in-bangladesh
#5
Daniela Ceccarelli, Munirul Alam, Anwar Huq, Rita R Colwell
β-lactams are antibiotic molecules able to inhibit cell wall biosynthesis. Among other mechanisms, resistance in Gram-negative bacteria is mostly associated with production of β-lactamase enzymes able to bind and hydrolyze the β-lactam ring. Extended-spectrum β-lactamases extend this ability also to third- and fourth-generation cephalosporins, as well as to carbapenems and monobactams. Vibrio cholerae is the causative agent of epidemic cholera and a public health burden for developing countries like Bangladesh...
2016: Frontiers in Public Health
https://www.readbyqxmd.com/read/27750388/oral-application-of-escherichia-coli-bacteriophage-safety-tests-in-healthy-and-diarrheal-children-from-bangladesh
#6
Shafiqul Alam Sarker, Bernard Berger, Ying Deng, Silas Kieser, Francis Foata, Deborah Moine, Patrick Descombes, Shamima Sultana, Sayeeda Huq, Pradip Kumar Bardhan, Valérie Vuillet, Fabienne Praplan, Harald Brüssow
A T4-like coliphage cocktail was given with different oral doses to healthy Bangladeshi children in a placebo-controlled randomized phase I safety trial. Fecal phage detection was oral dose dependent suggesting passive gut transit of coliphages through the gut. No adverse effects of phage application were seen clinically and by clinical chemistry. Similar results were obtained for a commercial phage preparation (Coliproteus from Microgen/Russia). By 16S rRNA gene sequencing, only a low degree of fecal microbiota conservation was seen in healthy children from Bangladesh who were sampled over a time interval of 7 days suggesting a substantial temporal fluctuation of the fecal microbiota composition...
October 17, 2016: Environmental Microbiology
https://www.readbyqxmd.com/read/27739287/oral-rehydration-therapy-20th-century-wonder
#7
J V Pai Dhungat
No abstract text is available yet for this article.
June 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27556051/the-effect-of-g-ors-along-with-rice-soup-in-the-treatment-of-acute-diarrhea-in-children-a-single-blind-randomized-controlled-trial
#8
Mojtaba Kianmehr, Ashraf Saber, Jalil Moshari, Reza Ahmadi, Mahdi Basiri-Moghadam
BACKGROUND: The world health organization guidelines for treatment of diarrhea in children emphasize on continued feeding together with prescription of oral rehydration solution (ORS) and supplementary zinc therapy. However, conflicting viewpoints exist regarding the optimal diet and dietary ingredients for children with diarrhea. Moreover, few studies have investigated the effect of rice soup along with ORS in the treatment of this disease. OBJECTIVES: This study aimed to explore effects of simultaneous taking of glucose oral rehydration solution (G-ORS) and rice soup in the treatment of acute diarrhea in 8 to 24-month-old children...
June 2016: Nursing and Midwifery Studies
https://www.readbyqxmd.com/read/27476499/economic-costs-to-caregivers-of-diarrhoea-treatment-among-children-below-5-in-rural-gujarat-india-findings-from-an-external-evaluation-of-the-dazt-programme
#9
Samuel D Shillcutt, Amnesty E LeFevre, Christa L Fischer Walker, Sunita Taneja, Robert E Black, Sarmila Mazumder
INTRODUCTION: Diarrhoea is a leading cause of mortality among young children in India although few receive the recommended treatment. The diarrhoea alleviation through zinc and oral rehydration salts (ORS) therapy (DAZT) team initiated a programme in Gujarat from 2011 to 2013 to increase coverage of these interventions through public and private providers at scale. This study evaluates the economic impact of diarrhoea to caregivers before and after the introduction of zinc and ORS at scale through the DAZT programme...
July 31, 2016: Health Policy and Planning
https://www.readbyqxmd.com/read/27449783/do-social-factors-predict-appropriate-treatment-of-child-diarrheal-disease-in-peru
#10
Kathryn Volpicelli, Alison M Buttenheim
Objectives Diarrheal disease is a significant cause of morbidity among children in Peru. Oral rehydration therapy (ORT) is a cost-effective evidence-based approach to treat diarrhea in young children, yet many Peruvian children in poorer households do not receive this life-saving treatment. This study investigates the social determinants of care-seeking behavior and utilization of appropriate home treatment for diarrheal episodes. Methods We used the nationally-representative 2008 Peru Demographic and Health Survey to: (1) describe the burden of non-bloody diarrheal disease among children <5 years old; and (2) identify socioeconomic correlates of care-seeking behavior and utilization/appropriateness of treatment among mothers of children with recent non-bloody diarrheal episodes (N = 1365)...
July 23, 2016: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/27401959/systematic-review-with-meta-analysis-ondansetron-for-vomiting-in-children-with-acute-gastroenteritis
#11
REVIEW
E Tomasik, E Ziółkowska, M Kołodziej, H Szajewska
BACKGROUND: Vomiting in children with acute gastroenteritis is a common symptom, and it is considered to be the main cause of failure of oral rehydration therapy. AIM: To systematically update evidence on the effects of ondansetron (5-HT3 serotonin antagonist) for vomiting in children with acute gastroenteritis. METHODS: The Cochrane Library, MEDLINE and EMBASE databases were searched up to April 2016, with no language restrictions, for randomised controlled trials (RCTs)...
September 2016: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27268427/clinical-practice-guideline-for-the-treatment-of-pediatric-acute-gastroenteritis-in-the-outpatient-setting
#12
Rebecca A Carson, Shawna S Mudd, P Jamil Madati
Acute gastroenteritis (AGE) is a common illness in childhood that usually can be treated in the outpatient setting. Inaccurate assessment or delayed treatment of AGE can lead to an increased risk for invasive interventions. A literature search was conducted using PubMed, CINAHL Plus, the Cochrane Library, and Embase. Results of the query were refined to narrow the focus of relevant studies for the provider caring for dehydrated children in the outpatient setting. Use of clinical dehydration scales to assess the level of dehydration and early initiation of oral rehydration therapy promote optimal patient outcomes...
November 2016: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/27262252/help-desk-answers-are-iv-fluids-better-than-oral-rehydration-for-children-with-acute-diarrhea-and-vomiting
#13
Suvag Patnaik, Mitali Nanda, Jose Tiburicio
Intravenous fluid therapy (IVF) has a slightly lower failure rate than oral replacement therapy (ORT) in children with acute gastroenteritis, but the clinical significance is questionable. IVF takes longer to initiate than ORT and lengthens the hospital stay.
April 2016: Journal of Family Practice
https://www.readbyqxmd.com/read/27197768/from-bench-to-bed-and-back-again-phage-therapy-of-childhood-escherichia-coli-diarrhea
#14
Shafiqul A Sarker, Harald Brüssow
Over the last 20 years, the Nestlé Research Center in Switzerland and the International Center for Diarrhoeal Diseases Research in Bangladesh have explored the efficacy of alternative biological agents for the treatment of diarrheal diseases. This paper reviews the work of this collaborative effort, particularly on Escherichia coli phage therapy (PT), and discusses the development of the project, starting with the isolation of T4-like coliphages from the stool of diarrhea patients, their pilot plant amplification and purification, and the constitution and testing of a cocktail of T4-like phages in mice...
May 2016: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/27131100/effect-of-dilute-apple-juice-and-preferred-fluids-vs-electrolyte-maintenance-solution-on-treatment-failure-among-children-with-mild-gastroenteritis-a-randomized-clinical-trial
#15
RANDOMIZED CONTROLLED TRIAL
Stephen B Freedman, Andrew R Willan, Kathy Boutis, Suzanne Schuh
IMPORTANCE: Gastroenteritis is a common pediatric illness. Electrolyte maintenance solution is recommended to treat and prevent dehydration. Its advantage in minimally dehydrated children is unproven. OBJECTIVE: To determine if oral hydration with dilute apple juice/preferred fluids is noninferior to electrolyte maintenance solution in children with mild gastroenteritis. DESIGN, SETTING, AND PARTICIPANTS: Randomized, single-blind noninferiority trial conducted between the months of October and April during the years 2010 to 2015 in a tertiary care pediatric emergency department in Toronto, Ontario, Canada...
May 10, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27077632/improving-the-management-of-acute-diarrhoea-and-dehydration-in-under-5-children-in-a-paediatric-referral-facility-in-lagos-nigeria
#16
Idowu O Senbanjo, Chin Lye Ch'ng, Stephen J Allen
BACKGROUND: Mortality from acute diarrhoea and dehydration (AD/D) in children is high despite existing management guidelines. AIM: The aim of this study was to identify deficiencies in the management of AD/D by health staff and assess changes in management after a training intervention in a paediatric referral facility in Lagos, Nigeria. METHODS: In a retrospective review of case notes, the management of AD/D was assessed using WHO guidelines as the standard...
January 29, 2016: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/27034520/the-role-of-drug-vendors-in-improving-basic-health-care-services-in-nigeria
#17
Jenny Liu, Lisa M Prach, Emily Treleaven, Mara Hansen, Jennifer Anyanti, Temple Jagha, Vince Seaman, Olufemi Ajumobi, Chinwoke Isiguzo
OBJECTIVE: To characterize patent and proprietary medicine vendors and shops in Nigeria and to assess their ability to help improve access to high-quality, primary health-care services. METHODS: In 2013 and 2014, a census of patent and proprietary medicine shops in 16 states of Nigeria was carried out to determine: (i) the size and coverage of the sector; (ii) the basic characteristics of shops and their staff; and (iii) the range of products stocked for priority health services, particularly for malaria, diarrhoea and family planning...
April 1, 2016: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/26973410/calcium-sensing-receptor-a-new-target-for-therapy-of-diarrhea
#18
REVIEW
Sam Xianjun Cheng
Management of acute diarrhea remains a global challenge, particularly in resource-limiting countries. Oral rehydration solution (ORS), a passive rehydrating therapy developed approximately 40 years ago, remains the mainstay treatment. Although ORS is effective for hydration, since it does not inhibit enterotoxin-mediated excessive secretion, reduced absorption and compromised barrier function - the primary mechanisms of diarrhea, ORS does not offer a rapid relief of diarrhea symptom. There are a few alternative therapies available, yet the use of these drugs is limited by their expense, lack of availability and/or safety concerns...
March 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/26950559/determinants-of-early-childhood-morbidity-and-proper-treatment-responses-in-vietnam-results-from-the-multiple-indicator-cluster-surveys-2000-2011
#19
Hwa-Young Lee, Nguyen Van Huy, Sugy Choi
BACKGROUND: Despite significant achievements in health indicators during previous decades, Vietnam lags behind other developing countries in reducing common early childhood illnesses, such as diarrhea and respiratory infections. To date, there has been little research into factors that contribute to the prevalence and treatment of childhood morbidity in Vietnam. OBJECTIVE: This study examines the determinants of diarrhea and 'illness with a cough' and treatments for each of the conditions among young children in Vietnam, and describes trends over time...
2016: Global Health Action
https://www.readbyqxmd.com/read/26949541/feasibility-study-of-short-hydration-using-oral-rehydration-solution-in-cisplatin-including-chemotherapy-of-lung-cancer
#20
Junya Sato, Naoto Morikawa, Hiroo Nitanai, Hiromi Nagashima, Satoru Nihei, Kohei Yamauti, Kenzo Kudo
BACKGROUND: Cisplatin (CDDP) is used as a key anticancer drug for solid cancers, including lung cancer. However, a large quantity of fluid replacement is required to prevent renal dysfunction. This requirement have made outpatient chemotherapies including CDDP administration less popular among the available therapeutic options. We designed a short-term hydration regimen combined with oral rehydration solution (ORS) that has a supplementary water ability equivalent to intravenous electrolyte maintenance infusion and investigated its safety and feasibility in the CDDP including chemotherapy...
2016: Journal of Pharmaceutical Health Care and Sciences
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