Read by QxMD icon Read

Allergic rhinitis & oral steroids

Ming-Tao Yang, Chia-Chun Chen, Wang-Tso Lee, Jao-Shwann Liang, Wen-Mei Fu, Yao-Hsu Yang
BACKGROUND: Increased prevalence of attention-deficit/hyperactivity disorder (ADHD) in children with allergic rhinitis (AR) has been reported. Our previous study showed that children with untreated AR had higher ADHD scores than did the controls. OBJECTIVE: This prospective follow-up study aimed to investigate whether elevated ADHD scores in children with AR could be decreased by AR treatment. METHODS: Sixty-eight children with AR (age range, 6-14 years) and who were drug naive were enrolled and evaluated by AR symptom score, ADHD symptom scores, and computerized continuous performance test, before and after AR therapy, which included nonpharmacologic intervention, oral antihistamines, and topical steroids...
May 2016: American Journal of Rhinology & Allergy
Wai Kun, Linda L D Zhong, Liang Dai, Chung-Wah Cheng, Ai-Ping Lu, Zhao-Xiang Bian
BACKGROUND: Allergic rhinitis (AR) is one of the most common allergic diseases. The conventional treatments of allergic rhinitis are oral anti-histamines, the use of intranasal corticosteroids, and immunotherapy. Dissatisfied with the ineffectiveness and side effects of these treatments, substantial numbers of patients are turning to alternative treatments like Chinese herbal medicine, particularly Tian Jiu (TJ). TJ is a form of moxibustion in which herbal patches are applied to specific acupoints on the skin...
2016: Trials
Rebecca Normansell, Kayleigh M Kew, Amy-Louise Bridgman
BACKGROUND: Asthma is a common long-term respiratory disease affecting approximately 300 million people worldwide. Approximately half of people with asthma have an important allergic component to their disease, which may provide an opportunity for targeted treatment. Sublingual immunotherapy (SLIT) aims to reduce asthma symptoms by delivering increasing doses of an allergen (e.g. house dust mite, pollen extract) under the tongue to induce immune tolerance. However, it is not clear whether the sublingual delivery route is safe and effective in asthma...
2015: Cochrane Database of Systematic Reviews
Veysel Yurttas, Murat Şereflican, Mustafa Erkoçoğlu, Elçin Hakan Terzi, Aysel Kükner, Mesut Oral
Allergic rhinitis is one of the most common health problems and has a major effect on quality of life. Although new-generation antihistamines and nasal steroids are the main treatment options, complete resolution cannot be obtained in some patients. Besides common side effects such as nasal irritation and epistaxis, the use of these drugs is controversial in some patients, such as pregnant or breastfeeding women. These findings highlight the need for new treatment options. Although phototherapy has been successfully used in the treatment of atopic dermatitis, which is an IgE-mediated disease and shares several common pathogenic features with allergic rhinitis, there are limited studies about its role in the treatment of allergic rhinitis...
August 2015: Journal of Photochemistry and Photobiology. B, Biology
Carlos E Baena-Cagnani, Giorgio W Canonica, Mohamed Zaky Helal, René Maximiliano Gómez, Enrico Compalati, Mario E Zernotti, Mario Sanchez-Borges, Fabio F Morato Castro, Margarita Murrieta Aguttes, Aida López-Garcia, Faheem A Tadros
Epidemiologic studies suggest that the prevalence of allergic rhinitis (AR) is rising worldwide. Several reports, in fact, indicate increasing trends in the prevalence of AR especially in developing countries, likely related to the environment and climate changes and the adoption of an urbanized Western lifestyle. The primary objective of the present study was to collect information about management in real-life settings, including a characterization of typical patients' profile referring to physicians, the disease features, the common approaches to diagnostic assessments and therapeutic decisions...
2015: World Allergy Organization Journal
Michael D Seidman, Richard K Gurgel, Sandra Y Lin, Seth R Schwartz, Fuad M Baroody, James R Bonner, Douglas E Dawson, Mark S Dykewicz, Jesse M Hackell, Joseph K Han, Stacey L Ishman, Helene J Krouse, Sonya Malekzadeh, James Whit W Mims, Folashade S Omole, William D Reddy, Dana V Wallace, Sandra A Walsh, Barbara E Warren, Meghan N Wilson, Lorraine C Nnacheta
OBJECTIVE: Allergic rhinitis (AR) is one of the most common diseases affecting adults. It is the most common chronic disease in children in the United States today and the fifth most common chronic disease in the United States overall. AR is estimated to affect nearly 1 in every 6 Americans and generates $2 to $5 billion in direct health expenditures annually. It can impair quality of life and, through loss of work and school attendance, is responsible for as much as $2 to $4 billion in lost productivity annually...
February 2015: Otolaryngology—Head and Neck Surgery
Lino Di Rienzo Businco, Andrea Di Rienzo Businco, Luca Ventura, Salvatore Laurino, Maria Lauriello
BACKGROUND: Allergic rhinitis (AR) presents as the main and most invasive symptom in the blocking of the nose. This condition is almost always related to hypertrophy of the inferior turbinates. When the medical treatments are found to be insufficient to solve the obstructive symptom of the patient, the quality of life is considerably impaired and it is often necessary to submit the patient to a surgical approach. In the present study we aimed to establish the efficacy and safety of a new technique recently introduced for the shrinkage of hypertrophic turbinates using a specific device, based on a new radiofrequency energy that does not produce thermal mucosal damage, viz...
March 2014: American Journal of Rhinology & Allergy
Kristen DeYoung, Jennifer L Wentzel, Rodney J Schlosser, Shaun A Nguyen, Zachary M Soler
BACKGROUND: Immunotherapy (IT) has been well established as an effective treatment for allergic rhinitis (AR), but little is known about the benefits of IT on clinical outcomes of comorbid chronic rhinosinusitis (CRS). The goal of this publication is to systematically review the literature regarding outcomes of IT in patients with atopic CRS. METHODS: A systematic review of the literature was conducted including studies that assessed the efficacy of IT on clinical outcome measures in CRS including without polyp, with polyp, and allergic fungal rhinosinusitis subgroups...
March 2014: American Journal of Rhinology & Allergy
Virat Kirtsreesakul, Jitanong Leelapong, Suwalee Ruttanaphol
BACKGROUND: Although nasal peak flow measurements have been proposed as a simple alternative method to assess nasal patency, which of nasal peak expiratory flow or nasal peak inspiratory flow (NPEF/NPIF) or the peak expiratory flow index or peak inspiratory flow index (PEFI/PIFI; the ratios between nasal and oral PEF or nasal and oral PIF, respectively) is the more accurate method is unclear. The aim of this study was to evaluate the correlation between NPEF, NPIF, PEFI, and PIFI, and blocked nose score (BNS) and mucociliary clearance time (MCCT) in diagnostic and follow-up assessments...
March 2014: American Journal of Rhinology & Allergy
E V Avallone, C Cassieri, M Zippi, R Pica, A Marcheggiano, P Vernia, E S Corazziari, P Paoluzi
Eosinophilic esophagitis (EoE) is the most common form of gastrointestinal disorders associated with eosinophilia. Typically, an inappropriate accumulation of eosinophils is found in the esophageal mucosa. EoE can be well managed and treated with several options that include an elimination diet, drug therapy (oral and topical steroids) and esophageal dilatations. We herein, report a case of a 49-year-old male affected by EoE associated to chest pain, treated with proton pump inhibitor without clinical response...
2014: La Clinica Terapeutica
Fulvio Braido, Francesca Sclifò, Matteo Ferrando, Giorgio Walter Canonica
Because of its burden on patient's lives and its impact on asthma, allergic rhinitis must be treated properly with more effective and safer treatments. According to guidelines by Allergic Rhinitis and Its Impact on Asthma (ARIA), the classification, pathogenesis, and treatment of allergic rhinitis are well defined. Currently, second-generation antihistamines and inhaled steroids are considered the cornerstone of first-line therapy. However, new formulations of available drugs (e.g., loratadine and rupatadine oral solution, ebastine fast-dissolving tablets, and the combination of intranasal fluticasone propionate and azelastine hydrochloride), recently discovered molecules (e...
April 2014: Current Allergy and Asthma Reports
Emel Çadallı Tatar, Unzile Akpınar Sürenoğlu, Ali Ozdek, Güleser Saylam, Hakan Korkmaz
Allergic rhinitis may significantly affect the patients' quality of life. The aim of this study was to compare the effects of nasal steroids alone, to nasal steroids plus Levocetirizine or Montelukast, on quality of life in persistent allergic rhinitis. This is a prospective, randomized study and included 56 patients with moderate to severe persistent allergic rhinitis. All patients had house dust mite allergy on skin prick test and we divided the patients into three groups. 1 month long medical treatment was; topical Mometasone furoate 200 mcg/day in the first group (n:14), Mometasone furoate 200 mcg/day plus oral Levocetirizine 5 mg/day in the second group (n:21), and Mometasone furoate 200 mcg/day plus oral Montelukast 10 mg/day in the third group (n:21)...
August 2013: Indian Journal of Otolaryngology and Head and Neck Surgery
Said Chaaban, Victor Salloum
SESSION TYPE: Miscellaneous Student/Resident Case Report PostersPRESENTED ON: Tuesday, October 23, 2012 at 01:30 PM - 02:30 PMINTRODUCTION: Chronic eosinophilic pneumonia is a syndrome usually associated with atopic manifestations, nonspecific pulmonary manifestations, chest imaging findings suggestive of peripheral alveolar opacities, as well as alveolar and blood eosinophilia. (1) Onset is usually insidious with symptoms lasting up to two to four weeks. Symptoms include dry cough, dyspnea, as well as other systemic manifestations such as fever and weight loss...
October 1, 2012: Chest
Samantha Gendelman, Andrew Zeft, Steven J Spalding
OBJECTIVE: To date only 38 cases of childhood-onset eosinophilic granulomatosis with polyangiitis (cEGPA; formerly Churg-Strauss syndrome) have been reported. Additional patients with cEGPA could enhance the understanding of this rare and life-threatening condition. Our objectives were (1) to determine the frequency of specific organ system involvement; (2) to examine initial therapeutic regimen; and (3) to document disease and therapy-related morbidity in a contemporary cohort of patients with cEGPA...
June 2013: Journal of Rheumatology
Ralph Mösges, Volker König, Juliane Köberlein
BACKGROUND: Allergic rhinitis represents a worldwide health problem. The prevalence is increasing. The aim of this study was to analyse the correlation between the severity of allergic rhinitis and an adequate treatment dose of modern oral antihistamines. METHODS: From a comprehensive databank containing data from ten different open-label prospective observational studies including raw data of 140,853 patients with allergic rhinitis, symptomatology variables were analysed and scored to study the effects of treatment with four antihistamines (Desloratadine, Ebastine, Fexofenadine, Levocetirizine) alone or in combination with intranasal corticosteroids...
June 2013: Allergology International: Official Journal of the Japanese Society of Allergology
Gary Rachelefsky, Judith Rosen Farrar
IMPORTANCE: Although the question of whether early diagnosis and treatment of pediatric allergic rhinitis (AR) improve disease control is important, a more crucial question is whether we can evaluate the effect of treatment on disease control using an impairment-risk model. OBJECTIVE: To conduct a systematic review evaluating application of a control model based on domains of impairment and risk (similar to that used for asthma) in pharmacotherapy for children with AR...
April 2013: JAMA Pediatrics
S H Arshad, S C Dharmage, F Ferreira, E D Fixman, G Gadermaier, M Hauser, A P Sampson, L M Teran, M Wallner, A J Wardlaw
As in previous years, we felt it would be of value to our readership to summarize the new information provided by the authors who have published in Clinical and Experimental Allergy in 2011 and set this in the context of recent advances in our understanding of the pathogenesis and management of allergic disease in all its many manifestations. In 2011, about 210 articles were published in Clinical and Experimental Allergy including editorials, reviews, opinion articles, guidelines, letters, book reviews and of course at the heart of the journal, papers containing original data...
December 2012: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
Masayuki Karaki, Kosuke Akiyama, Nozomu Mori
OBJECTIVE: Intranasal corticosteroids are effective for allergic rhinitis and broadly used in daily clinical practice. Systemic oral corticosteroids are also known to be effective for treatment of allergic rhinitis. These topical and systemic corticosteroids are both effective formulations for allergic rhinitis, and both drugs have some side effects. When treatment formulations for allergic rhinitis are selected based on side effects, topical corticosteroids are more commonly selected than systemic steroids...
June 2013: Auris, Nasus, Larynx
M Pascal, R Muñoz-Cano, Z Reina, A Palacín, R Vilella, C Picado, M Juan, J Sánchez-López, M Rueda, G Salcedo, A Valero, J Yagüe, J Bartra
BACKGROUND: Multiple plant-food sensitizations with a complex pattern of clinical manifestations are a common feature of lipid transfer protein (LTP)-allergic patients. Component-resolved diagnosis permits the diagnosis of the allergen sensitization profile. OBJECTIVE: We sought to clinically characterize and describe the plant-food and pollen molecular sensitization profile in patients with LTP syndrome. METHODS: Forty-five subjects were recruited, after being diagnosed with multiple plant-food allergies sensitized to LTP, but not to any other plant-food allergen, according to the molecular allergen panel tested (Pru p 3 (LTP), Pru p 1 (Bet v 1-like), Pru p 4 (profilin) and those included in a commercial microarray of 103 allergenic components)...
October 2012: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
David M Poetker, Luke A Jakubowski, Devyani Lal, Peter H Hwang, Erin D Wright, Timothy L Smith
BACKGROUND: Oral steroids are commonly used in the management of chronic rhinosinusitis (CRS) with and without nasal polyps (CRSwNP and CRSsNP, respectively). Past reports have included evaluation of the evidence for the use of oral steroids in CRS subtypes. However, a review with evidence-based recommendations for all CRS subtypes has never been performed. The purpose of this article is to provide a comprehensive, evidence-based approach for the utilization of oral steroids in the management of CRS...
February 2013: International Forum of Allergy & Rhinology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"