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https://www.readbyqxmd.com/read/29147099/changes-in-quality-characteristics-of-pork-patties-containing-antioxidative-fish-skin-peptide-or-fish-skin-peptide-loaded-nanoliposomes-during-refrigerated-storage
#1
Jing-Jing Bai, Jung-Gyu Lee, Sang-Yoon Lee, Soojin Kim, Mi-Jung Choi, Youngjae Cho
Marine fish skin peptides (FSP) have been widely studied due to their antioxidant and antimicrobial properties. We aimed to use a natural antioxidant, FSP, to replacing synthetic preservatives in a pork patty model, which is safer for human body. Moreover, nano-liposome technology can be applied for masking the fishy smell and improving the stability of this peptide. Therefore, in this study, the effects of FSP and FSP-loaded liposomes (FSPL) on pork patty were evaluated through the tests of thiobarbituric acid reactive substances (TBARS), color, cooking loss, texture, volatile basic nitrogen (VBN), and the pH value, during 14 d of refrigerated (4°C) storage...
2017: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/29131520/near-infrared-human-finger-measurements-based-on-self-calibration-point-simulation-and-in-vivo-experiments
#2
Hamootal Duadi, Idit Feder, Dror Fixler
Near-infrared light allows measuring tissue oxygenation. These measurements relay on oxygenation dependent absorption spectral changes. However, the tissue scattering, which is also spectral dependent, introduces an intrinsic error. Most methods focus on the volume reflectance from a semi-infinite sample. We have proposed examining the full scattering profile (FSP), which is the angular intensity distribution. A point was found, i.e. the iso-pathlength (IPL) point, which is not dependent on the tissue scattering, and can serve for self-calibration...
November 13, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/29127869/trans-boundary-air-pollution-in-a-city-under-various-atmospheric-conditions
#3
Ming Luo, Xiangting Hou, Yefu Gu, Ngar-Cheung Lau, Steve Hung-Lam Yim
Trans-boundary air pollution (TAP) is a crucial factor affecting air quality, and its contribution may vary over time and differ under various atmospheric conditions. This study firstly applies an integrated statistical scheme to estimate the contributions of TAP and local sources to air pollutants in a city, and then investigate the influences of tropical cyclones (TC) on TAP. Hong Kong is chosen as an example because of its significant and special TAP characteristics. This study focuses on four major air pollutants, namely, respirable and fine suspended particulates (RSP/PM10 and FSP/PM2...
November 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29115563/ormdl3-may-participate-in-the-pathogenesis-of-bronchial-epithelial%C3%A2-mesenchymal-transition-in-asthmatic-mice-with-airway-remodeling
#4
Qi Cheng, Yunxiao Shang
Asthma is a common chronic respiratory disease in children that is caused by a complex interaction between genetic and environmental factors. Orosomucoid‑like 3 (ORMDL3) is a candidate gene that has been strongly associated with asthma; however, the underlying mechanisms are unknown. ORMDL3 regulates the expression of metalloproteinases and transforming growth factor‑β, and ORMDL3 transgenic mice exhibit increased airway remodeling. Therefore, ORMDL3 may be associated with airway remodeling. The present study attempted to examine the associations between ORMDL3 and the severity of airway remodeling in asthmatic mice, and also to determine whether ORMDL3 induces epithelial‑mesenchymal transition (EMT) in the bronchial epithelium...
November 6, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29115553/endothelial%C3%A2-to%C3%A2-mesenchymal-transition-in-human-idiopathic-dilated-cardiomyopathy
#5
Yeqing Xie, Jianquan Liao, Yong Yu, Qi Guo, Yingzhen Yang, Junbo Ge, Haozhu Chen, Ruizhen Chen
Dilated cardiomyopathy (DCM) is characterized by left ventricular dilation and cardiac fibrosis. Emerging evidence indicated that endothelial‑to‑mesenchymal transition (Endo‑MT) is a crucial event during organ fibrosis. This study was performed to clarify whether Endo‑MT contributed to the progression of cardiac fibrosis in DCM. Cardiac samples from patients with DCM and control were obtained. The presence of endothelial markers, cluster of differentiation (CD)31 and vascular endothelial (VE)‑cadherin, and mesenchymal markers, α smooth muscle actin (SMA) and fibroblast‑specific protein 1 (FSP1) was performed using immunohistochemistry...
November 8, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29115426/recombinant-truncated-tgf%C3%A2-%C3%AE-receptor-ii-attenuates-carbon-tetrachloride%C3%A2-induced-epithelial%C3%A2-mesenchymal-transition-and-liver-fibrosis-in-rats
#6
Luxin Li, Hongzhi Li, Zhen Zhang, Junya Zheng, Yongping Shi, Jieting Liu, Yanan Cao, Xiaohuan Yuan, Yanhui Chu
Liver fibrosis is a pathological process of chronic liver diseases. In particular, epithelial‑mesenchymal transition (EMT) is a major source of myofibroblast structure in liver fibrosis. The present study investigated the effects of recombinant truncated transforming growth factor‑ß receptor II (rtTGFβRII) on EMT and liver fibrosis in a carbon tetrachloride (CCl4)‑induced rat model. A total of 24 rats were randomly separated into three groups: Normal control (NC), model (CCl4) and treatment (CCl4 + rtTGFβRII) groups...
October 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29111634/one-step-synthesis-of-cuo-cu2o-heterojunction-by-flame-spray-pyrolysis-for-cathodic-photoelectrochemical-sensing-of-l-cysteine
#7
Yuhan Zhu, Zuwei Xu, Kai Yan, Haibo Zhao, Jingdong Zhang
CuO-Cu2O heterojunction was synthesized via a one-step flame spray pyrolysis (FSP) process and employed as photoactive material in construction of a photoelectrochemical (PEC) sensing device. The surface analysis showed that CuO-Cu2O nanocomposites in the size less than 10 nm were formed and uniformly distributed on the electrode surface. Under visible light irradiation, the CuO-Cu2O-coated electrode exhibited admirable cathodic photocurrent response, owing to the favorable property of the CuO-Cu2O heterojunction such as strong absorption in the visible region and effective separation of photogenerated electron-hole pairs...
November 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29098989/an-application-of-the-krylov-fsp-ssa-method-to-parameter-fitting-with-maximum-likelihood
#8
Khanh N Dinh, Roger B Sidje
Monte Carlo methods such as the stochastic simulation algorithm (SSA) have traditionally been employed in gene regulation problems. However, there has been increasing interest to directly obtain the probability distribution of the molecules involved by solving the chemical master equation (CME). This requires addressing the curse of dimensionality that is inherent in most gene regulation problems. The finite state projection (FSP) seeks to address the challenge and there have been variants that further reduce the size of the projection or that accelerate the resulting matrix exponential...
November 3, 2017: Physical Biology
https://www.readbyqxmd.com/read/29055349/a-finite-state-projection-algorithm-for-the-stationary-solution-of-the-chemical-master-equation
#9
Ankit Gupta, Jan Mikelson, Mustafa Khammash
The chemical master equation (CME) is frequently used in systems biology to quantify the effects of stochastic fluctuations that arise due to biomolecular species with low copy numbers. The CME is a system of ordinary differential equations that describes the evolution of probability density for each population vector in the state-space of the stochastic reaction dynamics. For many examples of interest, this state-space is infinite, making it difficult to obtain exact solutions of the CME. To deal with this problem, the Finite State Projection (FSP) algorithm was developed by Munsky and Khammash [J...
October 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28984513/fascicular-shifting-a-novel-technique-to-overcome-large-nerve-defects
#10
Maria Hader, Matthias E Sporer, Aidan D Roche, Ewald Unger, Konstantin D Bergmeister, Robert Wakolbinger, Oskar C Aszmann
OBJECTIVE Over the last decade, a number of authors have investigated the utility of different biological and synthetic matrices as alternatives to conventional nerve grafts. However, the autologous nerve graft remains the gold standard, even though it often involves using a pure sensory nerve to reconstruct a mixed or even a pure motor nerve. Furthermore, limited donor sites often necessitate a significant mismatch of needed nerve tissue, especially for large proximal nerve defects such as brachial plexus lesions...
October 6, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28972737/friction-stir-processing-of-stainless-steel-for-ascertaining-its-superlative-performance-in-bioimplant-applications
#11
G Perumal, A Ayyagari, A Chakrabarti, D Kannan, S Pati, H S Grewal, S Mukherjee, S Singh, H S Arora
Substrate-cell interactions for a bioimplant are driven by substrate's surface characteristics. In addition, the performance of an implant and resistance to degradation are primarily governed by its surface properties. A bioimplant typically degrades by wear and corrosion in the physiological environment, resulting in metallosis. Surface engineering strategies for limiting degradation of implants and enhancing their performance may reduce or eliminate the need for implant removal surgeries and the associated cost...
October 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28960057/screening-precursor-solvent-combinations-for-li4ti5o12-energy-storage-material-using-flame-spray-pyrolysis
#12
Florian Meierhofer, Haipeng Li, Michael Gockeln, Robert Kun, Tim Grieb, Andreas Rosenauer, Udo Fritsching, Johannes Kiefer, Johannes Birkenstock, Lutz Mädler, Suman Pokhrel
The development and industrial application of advanced lithium based energy-storage materials are directly related to the innovative production techniques and the usage of inexpensive precursor materials. Flame spray pyrolysis (FSP) is a promising technique that overcomes the challenges in the production processes such as scalability, process control, material versatility, and cost. In the present study, phase pure anode material Li4Ti5O12 (LTO) was designed using FSP via extensive systematic screening of lithium and titanium precursors dissolved in five different organic solvents...
October 12, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28927611/assessing-the-reactivity-of-cellulose-by-oxidation-with-4-acetamido-2-2-6-6-tetramethylpiperidine-1-oxo-piperidinium-cation-under-mild-conditions
#13
Pegah Khanjani, Saija Väisänen, Ville Lovikka, Kaarlo Nieminen, Thad Maloney, Tapani Vuorinen
The accessibility and reactivity of cellulose are key parameters in its conversion into various products. Several indirect measures, such as water retention value (WRV), fiber saturation point (FSP) and specific surface area (SSA), are often used to characterize cellulosic samples for their reactivity. In this paper, we report on using oxidation with 4-acetamido-2,2,6,6-tetramethylpiperidine-1-oxo-piperidinium cation (4-AcNH-TEMPO(+)) as a probe reaction for the reactivity of cellulose in mild conditions (pH 9, room temperature)...
November 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28917588/association-between-fsp-cvhi-inflammatory-cytokines-and-the-incidence-of-primary-stroke
#14
Xiao-Yun Huang, Wen-Jin Fu, Zhi-Chang Chen, Zhi-Zhong Mei, Ying-Li Yu, Hao-Wei Fang, Yi-Hong Huang, Han Lin, Jian-Jun Chen, Ming-Xia Wang, Shao-Bing Guan, Wan-Xian Lu, Xiao-Ling Chen
This case-control study was designed to establish a new risk-prediction model for primary stroke using Framingham stroke profile (FSP), cerebral vascular hemodynamic indexes (CVHI) and plasma inflammatory cytokines including hs-CRP, IL-6, TNF-α and Lp-PLA2. A total of 101 primary stroke patients admitted to Dongguan Houjie Hospital between August 2014 and June 2015 were assigned into the case group, and 156 age- and gender-matched healthy subjects from the Houjie Community were allocated into the control group...
November 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28885575/effect-of-multi-pass-friction-stir-processing-on-mechanical-properties-for-aa2024-al%C3%A2-o%C3%A2-nanocomposites
#15
Essam Moustafa
In the present work, an aluminum metal matrix reinforced with (Al₂O₃) nanoparticles was fabricated as a surface composite sheet using friction stir processing (FSP). The effects of processing parameters on mechanical properties, hardness, and microstructure grain were investigated. The results revealed that multi-pass FSP causes a homogeneous distribution and good dispersion of Al₂O₃ in the metal matrix, and consequently an increase in the hardness of the matrix composites. A finer grain is observed in the microstructure examination in specimens subjected to second and third passes of FSP...
September 8, 2017: Materials
https://www.readbyqxmd.com/read/28846982/mir-200a-modulates-tgf-%C3%AE-1-induced-endothelial-to-mesenchymal-shift-via-suppression-of-grb2-in-haecs
#16
Hao Zhang, Jianguo Hu, Liming Liu
Endothelial-mesenchymal transition (EndMT) is closely associated with embryogenesis, injury restitution, tissue neogenesis, tumor progressions and viscera fibrosis. EndMT may occur in the proximal tubular endothelial cells, inducing fibroblasts to produce matrix and then accelerating the process of cardiac fibrosis. Transforming growth factor-β1 (TGF-β1), a profibrotic cytokine, was recently shown to be a crucial trigger of EndMT in tubular endothelial cells. Increasing evidence suggests that growth factor receptor-bound 2 (GRB2) dysfunction affects fibrocytes; thus, GRB2 may be a novel target for treating fibrosis...
November 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28839995/clinical-and-genetic-study-of-a-large-chinese-family-presented-with-familial-spontaneous-pneumothorax
#17
Huajie Xing, Yanguo Liu, Guanchao Jiang, Xiao Li, Yanyan Hou, Fan Yang, Jun Wang
BACKGROUND: Familial spontaneous pneumothorax (FSP) is an inherited disease, and Birt-Hogg-Dubé (BHD) syndrome is its leading cause. BHD syndrome is an autosomal dominant disorder characterized by pulmonary cysts, spontaneous pneumothorax, renal cancer, and skin fibrofolliculomas. It is caused by germline mutations in the FLCN gene. Thus far a variety of mutations have been reported; however, the unique characteristics of BHD syndrome-related FSP are still unclear. METHOD: We reviewed the family history of a large Chinese family that presented with FSP...
July 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28832878/development-of-phase-locking-and-frequency-representation-in-the-infant-frequency-following-response
#18
Katlyn B Van Dyke, Rachel Lieberman, Alessandro Presacco, Samira Anderson
Purpose: This study investigates the development of phase locking and frequency representation in infants using the frequency-following response to consonant-vowel syllables. Method: The frequency-following response was recorded in 56 infants and 15 young adults to 2 speech syllables (/ba/ and /ga/), which were presented in randomized order to the right ear. Signal-to-noise ratio and Fsp analyses were used to verify that individual responses were present above the noise floor...
August 22, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28804538/exendin-4-assisted-adipose-derived-mesenchymal-stem-cell-therapy-protects-renal-function-against-co-existing-acute-kidney-ischemia-reperfusion-injury-and-severe-sepsis-syndrome-in-rat
#19
Pei-Hsun Sung, Hsin-Ju Chiang, Christopher Glenn Wallace, Chih-Chao Yang, Yen-Ta Chen, Kuan-Hung Chen, Chih-Hung Chen, Pei-Lin Shao, Yung-Lung Chen, Sarah Chua, Han-Tan Chai, Yi-Ling Chen, Tien-Hung Huang, Hon-Kan Yip, Mel S Lee
This study tested the hypothesis that combined therapy with exendin-4 (Ex4) and autologous adipose-derived mesenchymal stem cells (ADMSCs) was superior to either alone for protecting renal function against acute kidney ischemia-reperfusion (IR; 40-min ischemia/27-h reperfusion) injury when complicated by sepsis syndrome (SS; by cecal-ligation-puncture). Adult-male Sprague-Dawley rats (n=40) were equally divided into group 1 (sham-control), group 2 (IR-SS), group 3 (IR-SS + Ex4, 10 μg/kg subcutaneously 30 min after reperfusion and daily for 3 days), group 4 [IR-SS + ADMSC (1...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28795560/pdi-derivative-through-fine-tuning-molecular-structure-for-fullerene-free-organic-solar-cells
#20
Hua Sun, Xin Song, Jian Xie, Po Sun, Peiyang Gu, Chang Mei Liu, Fei Chen, Qi Chun Zhang, Zhi-Kuan Chen, Wei Huang
A perylenediimide (PDI)-based small molecular (SM) acceptor with both an extended π-conjugation and a three dimensional structure concurrently is critical for achieving high performance PDI-based fullerene-free organic solar cells (OSCs). In this work, we designed and synthesized a novel PDI-based SM acceptor possessing both characteristics by fusing PDI units with a spiro core of 4,4'-spirobi[cyclopenta[2,1-b;3,4-b']dithiophene(SCPDT) through the -position of the thiophene rings. An enhanced strong absorption in the range of 350-520 nm and arisen LUMO energy level of FSP was observed, compared with previous reported acceptor SCPDT-PDI4, in which the PDI units and SCPDT are not fused...
August 10, 2017: ACS Applied Materials & Interfaces
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