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Daniel M LeBouthillier, Gordon J G Asmundson
Evidence supports exercise as an intervention for many mental health concerns; however, randomized controlled investigations of the efficacy of different exercise modalities and predictors of change are lacking. The purposes of the current trial were to: (1) quantify the effects of aerobic exercise and resistance training on anxiety-related disorder (including anxiety disorders, obsessive-compulsive disorder, and posttraumatic stress disorder) status, symptoms, and constructs, (2) evaluate whether both modalities of exercise were equivalent, and (3) to determine whether exercise enjoyment and physical fitness are associated with symptom reduction...
September 23, 2017: Journal of Anxiety Disorders
Elizabeth Quinlan-Jones, Sarah C Hillman, Mark D Kilby, Sheila M Greenfield
OBJECTIVE: To explore parental experiences of WES for prenatal diagnosis, and ascertain what influenced their decision-making to undergo testing. METHOD: Twelve women comprised a purposeful sample in a series of semi-structured interviews. All had received a fetal anomaly diagnosis on ultrasound. A topic guide was used, and transcripts were thematically analysed to elicit key themes. RESULTS: Five main themes (parental experiences of prenatal WES, need for information, consent/reasons for prenatal WES, sources of support for prenatal WES, and return of WES findings to families) emerged, some with multiple sub-themes...
October 19, 2017: Prenatal Diagnosis
Abriana Tasillo, Joshua A Salomon, Thomas A Trikalinos, C Robert Horsburgh, Suzanne M Marks, Benjamin P Linas
Importance: Testing for and treating latent tuberculosis infection (LTBI) is among the main strategies to achieve TB elimination in the United States. The best approach to testing among non-US born residents, particularly those with comorbid conditions, is uncertain. Objective: To estimate health outcomes, costs, and cost-effectiveness of LTBI testing and treatment among non-US born residents with and without medical comorbidities. Design, Setting, and Participants: Decision analytic tree and Markov cohort simulation model among non-US born residents with no comorbidities, with diabetes, with HIV infection, or with end-stage renal disease (ESRD) using a health care sector perspective with 3% annual discounting...
October 16, 2017: JAMA Internal Medicine
JingHui An, FengWu Shi, Su Liu, Jie Ma, QianLi Ma
Early postoperative cardiac complications of coronary artery bypass graft surgery, such as atrial fibrillation (AF) or myocardial infarction (MI), may be beneficially modulated by preoperative statins, involving their anti-inflammatory effects. There is uncertainty on the clinical merit of statin pretreatment. Addressing this, we conducted a meta-analysis of early cardiac complications and inflammatory markers following statin pretreatment in coronary artery bypass graft surgery. A search of Medline and Cochrane databases was undertaken to identify suitable studies...
July 26, 2017: Interactive Cardiovascular and Thoracic Surgery
Eltayeb Mohamed Ahmed, Alexandru Ciprian Visan, Graham Stuart, Serban Stoica
A 15-year-old patient with hypoplastic left heart syndrome underwent 3-stage palliation by the age of 3 years. He was later diagnosed with Loeys-Dietz syndrome. On follow-up imaging, the neoaorta was dilated at 50 mm in diameter. He underwent aortic root replacement with a composite valve conduit and hemiarch replacement, using a boat-shaped Dacron graft. The uncertainty of how univentricular circulation would tolerate long bypass time steered us away from a total arch replacement. His postoperative recovery was uneventful...
October 11, 2017: Interactive Cardiovascular and Thoracic Surgery
Andrea N Simpson, Alaina Garbens, Fahima Dossa, Peter C Coyte, Nancy N Baxter, Colleen D McDermott
OBJECTIVE: The objective of this study was to perform a cost-utility analysis of nonsurgical treatments for stress urinary incontinence (SUI) in healthy adult women with a health system perspective over a 1-year time horizon. METHODS: A decision tree model was constructed to evaluate the following nonsurgical treatment options for SUI in a simulated healthy adult female cohort who had failed Kegel exercises: pelvic floor muscle therapy (PFMT), a disposable tampon device (Impressa), a self-fitting intravaginal incontinence device (Uresta), and a traditional incontinence pessary...
October 18, 2017: Female Pelvic Medicine & Reconstructive Surgery
James Fingleton, Jo Hardy, Richard Beasley
PURPOSE OF REVIEW: To describe the rationale on which the treatable traits approach to the management of airways disease is based and the issues that need to be considered for its implementation in clinical practice. RECENT FINDINGS: In clinical practice, treatable traits can be classified according to both endotypes and phenotypes, broadly grouped within pulmonary, extrapulmonary, environmental and behavioural factors. Specific investigations and treatments are undertaken for each of the traits rather than a 'one size fits all' stepwise approach to pharmacological treatment which currently represents the core of asthma and chronic obstructive pulmonary disease (COPD) guidelines...
October 18, 2017: Current Opinion in Pulmonary Medicine
C M Marianno, M R Smith, K M Cook
This paper will examine deposition patterns of four radionuclides following the Fukushima-Daiichi accident. For nearly 13 d following the event, fission products were released into the environment through planned venting procedures and hydrogen explosions. To assist the government of Japan (GOJ) in the assessment of the releases, the National Nuclear Security Administration's Consequence Management Response Team (CMRT) deployed and took nearly 3 mo of measurements using airborne radiation sensors, fixed monitors, high purity germanium (HPGe) detectors, and health physics survey equipment...
October 18, 2017: Health Physics
Guijun Ning, Zundong Yin, Yixing Li, Huaqing Wang, Weizhong Yang
OBJECTIVE: The aims of this study were to estimate the cost-effectiveness of the Haemophilus influenzae type b (Hib) vaccine for the prevention of childhood pneumonia, meningitis and other vaccine-preventable diseases in mainland China from a societal perspective and to provide information about the addition of the Hib vaccine to Chinese immunization programs. METHODS: A decision tree and the Markov model were used to estimate the costs and effectiveness of the Hib vaccine versus no Hib vaccine for a birth cohort of 100,000 children in 2016...
October 19, 2017: Human Vaccines & Immunotherapeutics
Jason L Schwartz
The election of President Donald Trump raised grave concerns for the future of vaccination in the United States. Trump had frequently embraced-both before and during his election campaign-baseless and discredited allegations linking childhood vaccines to autism.(1) Shortly before his inauguration, he met with Robert F. Kennedy Jr, one of the most prominent and vocal critics of vaccine safety and current US vaccine policy, who announced after that meeting that he would lead a presidential "vaccine safety commission" charged with investigating these topics...
October 19, 2017: American Journal of Public Health
Bing Cheng, Agnelo Furtado, Robert J Henry
Background: Polyploidization contributes to the complexity of gene expression resulting in numerous related but different transcripts. This study explored the transcriptome diversity and complexity of tetraploid Arabica coffee ( Coffea arabica ) bean. Long-read sequencing (LRS) by Pacbio Isoform sequencing (Iso-seq) was used to obtain full-length transcripts without the difficulty and uncertainty of assembly required for reads from short read technologies. The tetraploid transcriptome was annotated and compared with data from the sub-genome progenitors...
August 30, 2017: GigaScience
Janeck J Scott-Fordsmand, Willie J G M Peijnenburg, Elena Semenzin, Bernd Nowack, Neil Hunt, Danail Hristozov, Antonio Marcomini, Muhammad-Adeel Irfan, Araceli Sánchez Jiménez, Robert Landsiedel, Lang Tran, Agnes G Oomen, Peter M J Bos, Kerstin Hund-Rinke
An Environmental Risk Assessment (ERA) for nanomaterials (NMs) is outlined in this paper. Contrary to other recent papers on the subject, the main data requirements, models and advancement within each of the four risk assessment domains are described, i.e., in the: (i) materials, (ii) release, fate and exposure, (iii) hazard and (iv) risk characterisation domains. The material, which is obviously the foundation for any risk assessment, should be described according to the legislatively required characterisation data...
October 19, 2017: International Journal of Environmental Research and Public Health
Andreas Mokros, Elmar Habermeyer, Helmut Küchenhoff
Psychiatric and psychological diagnoses are imperfect. Unlike somatic medicine, most psychological and psychiatric phenomena have no gold standard to establish their presence beyond reasonable doubt. Consequently, prevalence estimates are based on the average agreement of imperfect evaluators. Küchenhoff, Augustin, and Kunz (2012) provided a statistical method for estimating confidence intervals of the prevalence based on the well-known kappa coefficient of interrater agreement. We expand this method and derive confidence intervals for the probability of a diagnosis being true (i...
October 19, 2017: Psychological Assessment
Yuanheng Xiong, Xiaodong Zhang, Shuangyan He, Deric J Gray
Even though it is well known that both the magnitude and detailed angular shape of scattering (phase function, PF), particularly in the backward angles, affect the color of the ocean, the current remote-sensing reflectance (Rrs) models typically account for the effect of its magnitude only through the backscattering coefficient (bb). Using 116 volume scattering function (VSF) measurements previously collected in three coastal waters around the U.S. and in the water of the North Atlantic Ocean, we re-examined the effect of particle PF on Rrs in four scenarios...
August 20, 2017: Applied Optics
Haoliang Zhang, Jun Yang, Chuang Li, Zhangjun Yu, Zhe Yang, Yonggui Yuan, Feng Peng, Hanyang Li, Changbo Hou, Jianzhong Zhang, Libo Yuan, Jianming Xu, Chao Zhang, Quanfu Yu
Measurement error for the polarization extinction ratio (PER) of a multifunctional integrated optic chip (MFIOC) utilizing white light interferometry was analyzed. Three influence factors derived from the all-fiber device (or optical circuit) under test were demonstrated to be the main error sources, including: 1) the axis-alignment angle (AA) of the connection point between the extended polarization-maintaining fiber (PMF) and the chip PMF pigtail; 2) the oriented angle (OA) of the linear polarizer; and 3) the birefringence dispersion of PMF and the MFIOC chip...
August 20, 2017: Applied Optics
Juan Du, Yadan Zhu, Shiguang Li, Junxuan Zhang, Yanguang Sun, Huaguo Zang, Dan Liu, Xiuhua Ma, Decang Bi, Jiqiao Liu, Xiaolei Zhu, Weibiao Chen
A ground-based double-pulse integrated path differential absorption (IPDA) instrument for carbon dioxide (CO2) concentration measurements at 1572 nm has been developed. A ground experiment was implemented under different conditions with a known wall located about 1.17 km away acting as the scattering hard target. Off-/offline testing of a laser transmitter was conducted to estimate the instrument systematic and random errors. Results showed a differential absorption optical depth (DAOD) offset of 0.0046 existing in the instrument...
September 1, 2017: Applied Optics
Andreas Fischer
The basic metrological task in speckle photography is to quantify displacements of speckle patterns, allowing for instance the investigation of the mechanical load and modification of objects with rough surfaces. However, the fundamental limit of the measurement uncertainty due to photon shot noise is unknown. For this reason, the Cramér-Rao bound (CRB) is derived for speckle displacement measurements, representing the squared minimal achievable measurement uncertainty. As result, the CRB for speckle patterns is only two times the CRB for an ideal point light source...
September 1, 2017: Applied Optics
Yang Xiao, Lirong Qiu, Weiqian Zhao
This paper proposes a laser confocal cylindrical radius of the curvature measurement (CCRM) method. The CCRM method precisely identifies the positions of the vertex and curvature center of the test cylindrical surface by using the property so that the maximum point of the laser confocal axial intensity curve precisely corresponds to the focus of the laser confocal measurement system, and the accurate distance of these two positions is obtained by the distance measuring instrument, thus achieving the precise measurement of the cylindrical radius...
August 10, 2017: Applied Optics
Maik Rahlves, Bernhard Roth, Eduard Reithmeier
Confocal microscopy is one of the dominating measurement techniques in surface metrology, with an enhanced lateral resolution compared to alternative optical methods. However, the axial resolution in confocal microscopy is strongly dependent on the accuracy of signal evaluation algorithms, which are limited by random noise. Here, we discuss the influence of various noise sources on confocal intensity signal evaluating algorithms, including center-of-mass, parabolic least-square fit, and cross-correlation-based methods...
July 20, 2017: Applied Optics
Vyacheslav B Podobedov, George P Eppeldauer, Thomas C Larason
A gain measurement technique for the calibration of night vision goggles (NVG) is proposed and evaluated. This technique is based on the radiance measurements at the input and output of the NVG. In contrast to the old definition, which uses a non-International System of Units (SI) traceable luminance, the "equivalent luminance unit," the suggested technique utilizes the radiance quantities that are traceable to the SI units through National Institute of Standards and Technology (NIST) standards. Due to the implementation of the scaling coefficients originating from the NVG spectral responsivities, the same NVG gain is expected within both techniques...
July 20, 2017: Applied Optics
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