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https://www.readbyqxmd.com/read/29457404/-perioperative-and-drug-management-of-patients-with-rheumatoid-arthritis-treated-with-joint-replacement
#1
REVIEW
Jun Liu, Ping Zhen, Sheng-Hu Zhou, Qi Tian, Hui Chen, Jie Shi, Wei Wang, Xiao-le He, Xu-Sheng Li
Rheumatoid arthritis (RA) is a most common inflammatory joint disease with direct invasion of joint synovial membrane, cartilage and bone. Currently, although the RA mitigation drugs are being improved continously, but these drugs only can delay the development of joint dysfunction. Total hip arthroplasty or total knee arthroplasty(THA or TKA) has become the only choices for patients with advanced RA, and the joint function and deformity of the patients after surgical treatment can be improved to some extent...
November 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29456776/what-percentage-of-patients-is-a-candidate-for-unicompartmental-knee-replacement-at-a-chinese-arthroplasty-center
#2
Yong He, Lianbo Xiao, Weitao Zhai, Maximilian F Kasparek, Guilin Ouyang, Friedrich Boettner
Background: Data on indication of Unicompartmental Knee Arthroplasty (UKA) in the Asian population are currently not available. The current paper evaluates patients undergoing knee replacement at a Chinese Orthopaedic Specialty Hospital to report the percentage of patients who meet radiographic and clinical indication criteria for UKA. Methods: Over a one-year period 463 consecutive patients (515 knees) underwent primary knee replacement surgery. Clinical data were recorded and preoperative radiographs were assessed...
2018: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29455686/cost-utility-analysis-of-private-contracting-to-reduce-public-waiting-times-for-joint-replacement-surgery
#3
Jonathan Karnon, Bahareh Mesgarian Haghighi, Babu Sajjad, Sokunthea Yem, Anuji Gamage, Aaron Thorpe
OBJECTIVES: Earlier treatment of publicly funded patients may achieve health gains that justify the additional costs of reducing waiting times. This study reports on the cost-effectiveness of implementing a private contracting model to meet alternative maximum waiting time targets for publicly funded patients undergoing total knee replacement surgery in Australia. METHODS: A linked decision tree and cohort Markov model was developed and populated and validated using secondary data sources to represent the pathways, costs, and quality adjusted life-years (QALYs) gained of non-urgent patients with alternative waiting times for total knee replacement surgery to a maximum age of 100 years...
February 19, 2018: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/29454601/cross-linked-polyethylene-does-not-reduce-wear-in-total-knee-arthroplasty
#4
S Lasurt-Bachs, P Torner, F Maculé, E Prats, F Menéndez-García, J Ríos-Guillermo, A Torrents
AIM: To compare two different types of inserts: Ultra-high molecular weight polyethylene (UHMWPE) and cross-linked polyethylene with a quantitative and qualitative study of polyethylene wear particles in synovial fluid 3 years after total knee arthroplasty. MATERIAL AND METHODS: A prospective, randomized, controlled cohort study with blinded evaluation was carried out on 25 patients undergoing staged bilateral total knee replacement, 6 months apart. Knee arthrocentesis was performed on 12 patients 3 years after surgery, and the polyethylene particles were analyzed...
February 14, 2018: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/29452971/medial-overhang-of-the-tibial-component-is-associated-with-higher-risk-of-inferior-knee-injury-and-osteoarthritis-outcome-score-pain-after-knee-replacement
#5
Christian S Nielsen, Audrey Nebergall, James Huddleston, Thomas Kallemose, Henrik Malchau, Anders Troelsen
BACKGROUND: The aim of this prospective multicenter study is to investigate the association among (1) tibial site-specific overhang of medial, anterior, and lateral overhang in relation to Knee Injury and Osteoarthritis Outcome Score pain 1 year after surgery (1 Y KOOS pain) and (2) the malalignment of TKA components including overall malalignment in relation to 1 Y KOOS pain. METHODS: From 10 centers, across 4 continents, 323 patients were enrolled from October 2011 to February 2014...
December 28, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29444907/response-to-bisphosphonates-reduce-the-risk-of-knee-replacement-we-need-more-analyses-by-li-et-al
#6
Tuhina Neogi, Shanshan Li, Christine Peloquin, Devyani Misra, Yuqing Zhang
No abstract text is available yet for this article.
February 14, 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29443842/corr-international-asia-pacific-is-price-capping-of-knee-replacement-implants-in-india-a-good-idea
#7
Sahil Sanghavi
No abstract text is available yet for this article.
March 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29441501/choosing-between-unicompartmental-and-total-knee-replacement-what-can-economic-evaluations-tell-us-a-systematic-review
#8
REVIEW
Edward Burn, Alexander D Liddle, Thomas W Hamilton, Sunil Pai, Hemant G Pandit, David W Murray, Rafael Pinedo-Villanueva
BACKGROUND AND OBJECTIVE: Patients with anteromedial arthritis who require a knee replacement could receive either a unicompartmental knee replacement (UKR) or a total knee replacement (TKR). This review has been undertaken to identify economic evaluations comparing UKR and TKR, evaluate the approaches that were taken in the studies, assess the quality of reporting of these evaluations, and consider what they can tell us about the relative value for money of the procedures. METHODS: A search of MEDLINE, EMBASE and the Centre for Reviews and Dissemination National Health Service Economic Evaluation Database was undertaken in January 2016 to identify relevant studies...
December 2017: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29441423/how-do-mri-detected-subchondral-bone-marrow-lesions-bmls-on-two-different-mri-sequences-correlate-with-clinically-important-outcomes
#9
Siti Maisarah Mattap, Dawn Aitken, Karen Wills, Laura Laslett, Changhai Ding, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Stephen E Graves, Michelle Lorimer, Flavia Cicuttini, Graeme Jones
The aim of this study is to describe the association of bone marrow lesions (BMLs) present on two different MRI sequences with clinical outcomes, cartilage defect progression, cartilage volume loss over 2.7 years, and total knee replacement (TKR) over 13.3 years. 394 participants (50-80 years) were assessed at baseline and 2.7 years. BML presence at baseline was scored on T1-weighted fat-suppressed 3D gradient-recalled acquisition (T1) and T2-weighted fat-suppressed 2D fast spin-echo (T2) sequences. Knee pain, function, and stiffness were assessed using WOMAC...
February 13, 2018: Calcified Tissue International
https://www.readbyqxmd.com/read/29438603/from-early-radiographic-knee-osteoarthritis-to-joint-arthroplasty-determinants-of-structural-progression-and-symptoms
#10
Frank W Roemer, C Kent Kwoh, Tomoko Fujii, Michael J Hannon, Robert M Boudreau, David J Hunter, Felix Eckstein, Markus R John, Ali Guermazi
OBJECTIVE: Aims were to assess (1) structural progression in knees with no/mild radiographic osteoarthritis (ROA) (i.e. Kellgren-Lawrence (K-L) grades 0 to 2) that will undergo knee replacement (KR) during a 5-year period; (2) differences in structural damage on MRI between knees with no/mild ROA vs. those with severe ROA (i.e. K-L 3 and 4) at baseline; and (3) differences in pain levels between those groups. METHODS: All participants who underwent KR from baseline (BL) to 60 months were drawn from the Osteoarthritis Initiative...
February 13, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29436472/a-novel-variant-in-glis3-is-associated-with-osteoarthritis
#11
Elisabetta Casalone, Ioanna Tachmazidou, Eleni Zengini, Konstantinos Hatzikotoulas, Sophie Hackinger, Daniel Suveges, Julia Steinberg, Nigel William Rayner, arcOGEN Consortium, Jeremy Mark Wilkinson, Kalliope Panoutsopoulou, Eleftheria Zeggini
OBJECTIVES: Osteoarthritis (OA) is a complex disease, but its genetic aetiology remains poorly characterised. To identify novel susceptibility loci for OA, we carried out a genome-wide association study (GWAS) in individuals from the largest UK-based OA collections to date. METHODS: We carried out a discovery GWAS in 5414 OA individuals with knee and/or hip total joint replacement (TJR) and 9939 population-based controls. We followed-up prioritised variants in OA subjects from the interim release of the UK Biobank resource (up to 12 658 cases and 50 898 controls) and our lead finding in operated OA subjects from the full release of UK Biobank (17 894 cases and 89 470 controls)...
February 7, 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29435992/feasibility-and-safety-of-a-cemented-peek-on-pe-knee-replacement-in-a-goat-model-a-preliminary-study
#12
Zhe Du, Zhonglin Zhu, Bing Yue, Zhanchun Li, You Wang
Polyether-ether-ketone (PEEK) is a potential alternative to metal alloys for use in the orthopedic implants; however, an in vivo study in an appropriate animal model is essential and has not yet been initiated. The aim of the present study was to gather some preliminary evidence regarding the performance and safety of a cemented PEEK-based knee replacement device in a goat model. Fifteen adult goats were randomly divided into two groups; the control group (n = 5), which received a sham operation, and the experimental group (n = 10), which received a total knee arthroplasty with a PEEK-based knee replacement device...
February 13, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29435622/high-bacterial-contamination-rate-of-electrocautery-tips-during-total-hip-and-knee-arthroplasty
#13
Hussein Abdelaziz, Akos Zahar, Christian Lausmann, Thorsten Gehrke, Helmut Fickenscher, Eduardo M Suero, Matthias Gebauer, Mustafa Citak
PURPOSE: The aim of the study was to quantify the bacterial contamination rate of electrocautery tips during primary total joint replacement (TJR), as well as during aseptic and septic revision TJR. METHODS: A total of 150 electrocautery tips were collected between April and July 2017. TJR surgeries were divided into three groups: (1) primary, (2) aseptic and (3) septic revisions. In each group, a total of 50 electrocautery tips were collected. A monopolar electrocautery with a reusable stainless-steel blade tip was used in all cases...
February 12, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29435023/primary-malignant-perivascular-epithelioid-cell-neoplasm-pecoma-of-the-bone-mimicking-granular-cell-tumor-in-core-biopsy-a-case-report-and-literature-review
#14
Sam Sadigh, Preya Shah, Kristy Weber, Ronnie Sebro, Paul J Zhang
The present study investigated the case of a 46-year-old female with primary malignant perivascular epithelioid cell neoplasm (PEComa) of the femur. The patient presented with a 5-month history of right distal thigh pain following trauma. Radiographs of the right distal femur revealed a mixed lytic and sclerotic lesion with subtle areas of cortical destruction and soft tissue extension, consistent with an aggressive tumor. A core biopsy revealed an epithelioid tumor with granular cell features, but a definitive diagnosis could not be made...
March 2018: Oncology Letters
https://www.readbyqxmd.com/read/29432264/longitudinal-growth-and-pqct-measures-in-hutterite-children-and-grandchildren-are-associated-with-prevalence-of-hip-or-knee-replacement-resulting-from-osteoarthritis-in-parents-and-grandparents
#15
Lee Weidauer, Tianna Beare, Teresa Binkley, Maggie Minett, Bonny Specker
BACKGROUND: Osteoarthritis (OA) is one of the leading causes of disability in the world. Several genes are associated with the development of OA, and previous studies have shown adult children of individuals with OA have higher areal bone mineral density (BMD). Because childhood is an important period of growth and bone development, and body composition is known to be associated with BMD, we speculated that there may be differences in growth and bone measures among young children with a genetic predisposition to OA...
February 8, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29431491/customizable-pre-printed-consent-forms-a-solution-in-light-of-the-montgomery-ruling
#16
Deborah Owen, Nick Aresti, Alex Mulligan, Dennis Kosuge
INTRODUCTION: This article presents an audit cycle supported quality improvement project addressing best practice in the consent process for lower limb arthroplasty which takes into account the new standard in surgical consent and the importance of material risks. METHODS: 50 consecutive total hip and total knee replacement consent forms over a 3-month period were reviewed for legibility and completeness. Following the introduction of a new, pre-printed but customizable consent form the review process was repeated...
February 2, 2018: British Journal of Hospital Medicine
https://www.readbyqxmd.com/read/29428675/a-human-osteoarthritis-osteochondral-organ-culture-model-for-cartilage-tissue-engineering
#17
P Yeung, W Zhang, X N Wang, C H Yan, B P Chan
RATIONALE: In vitro human osteoarthritis (OA)-mimicking models enabling pathophysiological studies and evaluation of emerging therapies such as cartilage tissue engineering are of great importance. OBJECTIVE: We describe the development and characterization of a human OA osteochondral organ culture. We also apply this model for evaluation of the phenotype maintenance of a human MSC derived engineered cartilage, as an example of emerging therapeutics, under long term exposure to the OA-mimicking environment...
February 4, 2018: Biomaterials
https://www.readbyqxmd.com/read/29427125/survival-complications-and-functional-outcomes-of-cemented-megaprostheses-for-high-grade-osteosarcoma-around-the-knee
#18
Chunlin Zhang, Jianping Hu, Kunpeng Zhu, Tao Cai, Xiaolong Ma
PURPOSE: We initiated a retrospective study on the long-term survival of cemented endoprostheses for bone tumours around the knee to answer the following questions: (1) What was the survival of these patients? (2) What was the overall survival of cemented prostheses around the knee? (3) What types of failures were observed in these reconstructions? (4) Did the survival and complications vary according to the site of the implant? (5) What was the functional result after cemented prosthesis replacement around the knee? METHODS: From January 2006 to December 2013, 108 consecutive patients with an average age of 25 years, who had mature bone development as evidenced by imaging examinations, underwent 108 cemented endoprosthetic knee replacements for osteosarcoma resection...
February 9, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29426557/-patients-taking-an-active-role-in-their-care-in-ambulatory-knee-replacement-surgery
#19
REVIEW
Sabrina Rubin, Solange Franger, Adeline Martin, Régis Lorguilloux, Farid Kneife
National recommendations encourage the development of ambulatory surgery. This form of treatment, reserved mainly for short procedures, can also be used for more complex operations such as a total knee replacement. The teams at Vitré general hospital share their experience and emphasise the need to ensure the compliance of patients and their family.
February 2018: Revue de L'infirmière
https://www.readbyqxmd.com/read/29426007/how-do-patients-trade-off-surgeon-choice-and-waiting-times-for-total-joint-replacement-a-discrete-choice-experiment
#20
Deborah A Marshall, Ken Deal, Barbara Conner-Spady, Eric Bohm, Gillian Hawker, Lynda Loucks, Karen V MacDonald, Tom Noseworthy
OBJECTIVE: Patients face significant waiting times for hip and knee total joint replacement (TJR) in publicly funded healthcare systems. We aimed to assess how surgeon selection and reputation affect patients' willingness to wait for TJR. DESIGN: We assessed patient preferences using a discrete choice experiment questionnaire with 12 choice scenarios administered to patients referred for TJR. Based on qualitative research, pre- and pilot-testing, we characterized each scenario by five attributes: surgeon reputation, surgeon selection, waiting time to surgeon visit (initial consultation), waiting time to surgery, and travel time to hospital...
February 6, 2018: Osteoarthritis and Cartilage
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