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https://www.readbyqxmd.com/read/29784586/ultrasound-mediated-gene-delivery-enhances-tendon-allograft-integration-in-mini-pig-ligament-reconstruction
#1
Maxim Bez, Thomas J Kremen, Wafa Tawackoli, Pablo Avalos, Dmitriy Sheyn, Galina Shapiro, Joseph C Giaconi, Shiran Ben David, Jess G Snedeker, Zulma Gazit, Katherine W Ferrara, Dan Gazit, Gadi Pelled
Ligament injuries occur frequently, substantially hindering routine daily activities and sports participation in patients. Surgical reconstruction using autogenous or allogeneic tissues is the gold standard treatment for ligament injuries. Although surgeons routinely perform ligament reconstructions, the integrity of these reconstructions largely depends on adequate biological healing of the interface between the ligament graft and the bone. We hypothesized that localized ultrasound-mediated, microbubble-enhanced therapeutic gene delivery to endogenous stem cells would lead to significantly improved ligament graft integration...
April 26, 2018: Molecular Therapy: the Journal of the American Society of Gene Therapy
https://www.readbyqxmd.com/read/29781788/a-review-of-the-reliability-of-biomechanical-variables-produced-during-the-isometric-mid-thigh-pull-and-isometric-squat-and-the-reporting-of-normative-data
#2
Claire J Brady, Andrew J Harrison, Thomas M Comyns
The use of isometric strength testing, particularly the isometric mid-thigh pull (IMTP) has increased dramatically over the last decade. The IMTP and isometric squat (ISqT) provide one aspect of performance monitoring with variables such as peak force and rate of force development being derived from the force-time curve. The reliability of some of these variables is conflicting in the literature, and the reporting of the reliability is not standardised across the research. The majority of research only reports intraclass correlation coefficients with very few studies reporting coefficient of variation and 90% confidence intervals...
May 21, 2018: Sports Biomechanics
https://www.readbyqxmd.com/read/29781550/walking-gait-asymmetries-six-months-following-anterior-cruciate-ligament-reconstruction-predict-twelve-month-patient-reported-outcomes
#3
Brian Pietrosimone, J Troy Blackburn, Darin A Padua, Steven J Pfeiffer, Hope C Davis, Brittney A Luc-Harkey, Matthew S Harkey, Laura E Stanley, Barnett S Frank, R Alexander Creighton, Ganesh M Kamath, Jeffery T Spang
The study sought to determine the association between gait biomechanics (vertical ground reaction force [vGRF], vGRF loading rate [vGRF-LR]) collected six months following anterior cruciate ligament reconstruction (ACLR) with patient-reported outcomes at twelve months following ACLR. Walking gait mechanics and all subsections of the Knee Injury and Osteoarthritis Outcomes Score (KOOS) were collected at six and twelve months following ACLR, respectively, in 25 individuals with a unilateral ACLR. Peak vGRF and peak instantaneous vGRF-LR were extracted from the first 50% of the stance phase...
May 21, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29763339/the-v-shaped-distal-triceps-tendon-repair-a-comparative-biomechanical-analysis
#4
Bastian Scheiderer, Florian B Imhoff, Daichi Morikawa, Lucca Lacheta, Elifho Obopilwe, Mark P Cote, Andreas B Imhoff, Augustus D Mazzocca, Sebastian Siebenlist
BACKGROUND: Restoring footprint anatomy, minimizing gap formation, and maximizing the strength of distal triceps tendon repairs are essential factors for a successful healing process and return to sport. HYPOTHESIS: The novel V-shaped distal triceps tendon repair technique with unicortical button fixation closely restores footprint anatomy, provides minimal gap formation and high ultimate failure load, and minimizes iatrogenic fracture risk in acute/subacute distal triceps tendon tears...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29761113/differences-in-hip-joint-biomechanics-and-muscle-activation-in-individuals-with-femoroacetabular-impingement-compared-with-healthy-asymptomatic-individuals-is-level-ground-gait-analysis-enough
#5
Derek J Rutherford, Janice Moreside, Ivan Wong
Background: Femoroacetabular impingement (FAI) is a recognized cause of hip and groin pain and a significant factor in hip joint function during sport. Objective tests for understanding hip function are lacking in this population. Purpose: To determine whether biomechanical and electromyographic features of hip function during level-ground walking differ between a group diagnosed with FAI and those with no symptoms of FAI. Study Design: Controlled laboratory study...
May 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29739301/sub-elite-football-players-with-hip-related-groin-pain-and-positive-flexion-adduction-internal-rotation-test-exhibit-distinct-biomechanical-differences-compared-with-the-asymptomatic-side
#6
Matthew G King, Adam I Semciw, Harvi F Hart, Anthony G Schache, Kane J Middleton, Josh J Heerey, Rintje Agricola, Kay M Crossley
Study Design Observational cross-sectional study. Background Hip-related groin pain is common in sub-elite football players and may be associated with altered hip biomechanics. Objectives To compare the hip biomechanics, bony hip morphology associated with femoroacetabular impingement (FAI) syndrome, and hip strength and range of motion between the symptomatic and asymptomatic limb of sub-elite football players with unilateral hip-related groin pain and a positive flexion adduction internal rotation test. Methods Fifteen sub-elite football (soccer) players with unilateral hip-related groin pain and a positive flexion adduction internal rotation test were recruited...
May 8, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29736728/effects-and-dose-response-relationship-of-balance-training-on-balance-performance-in-youth-a-systematic-review-and-meta-analysis
#7
REVIEW
Arnd Gebel, Melanie Lesinski, David G Behm, Urs Granacher
BACKGROUND: Effects and dose-response relationships of balance training on measures of balance are well-documented for healthy young and old adults. However, this has not been systematically studied in youth. OBJECTIVES: The objectives of this systematic review and meta-analysis were to quantify effects of balance training (BT) on measures of static and dynamic balance in healthy children and adolescents. Additionally, dose-response relations for BT modalities (e...
May 7, 2018: Sports Medicine
https://www.readbyqxmd.com/read/29731951/advanced-computational-methods-in-bio-mechanics
#8
REVIEW
Waleed M S Al Qahtani, Mohamed I El-Anwar
A novel partnership between surgeons and machines, made possible by advances in computing and engineering technology, could overcome many of the limitations of traditional surgery. By extending surgeons' ability to plan and carry out surgical interventions more accurately and with fewer traumas, computer-integrated surgery (CIS) systems could help to improve clinical outcomes and the efficiency of healthcare delivery. CIS systems could have a similar impact on surgery to that long since realised in computer-integrated manufacturing...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29721837/change-of-direction-biomechanics-is-what-s-best-for-anterior-cruciate-ligament-injury-prevention-also-best-for-performance
#9
REVIEW
Aaron S Fox
Change-of-direction maneuvers (e.g., side-step cutting) are an important aspect of performance in multi-directional sports, but these maneuvers are also associated with anterior cruciate ligament (ACL) injury. Despite this, the impact of biomechanics on ACL injury risk and performance is often examined in isolation. The purpose of this review was to examine the alignment between biomechanical recommendations for ACL injury prevention and performance with regard to change-of-direction maneuvers. Several studies linking change-of-direction biomechanics to both ACL injury risk and performance were examined...
May 2, 2018: Sports Medicine
https://www.readbyqxmd.com/read/29702719/evaluation-of-a-novel-degradable-synthetic-biomaterial-patch-for-augmentation-of-tendon-healing-in-a-large-animal-model
#10
Wayne K Gersoff, Chantelle C Bozynski, Cristi R Cook, Ferris M Pfeiffer, Keiichi Kuroki, James L Cook
Tendon injury is common in sports. The standard of care (SOC) for tendon repair is surgical treatment. However, restored tendons often lack complete strength and functionality, and surgical repair is often unsuccessful. This controlled laboratory study investigates the healing of an Artelon patch (AP)-augmented tendon versus tendon repair alone in a preclinical canine patellar tendon defect model. Full-thickness proximal and distal flap defects were created in the patella tendons of eight purpose-bred research mongrel dogs...
April 27, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29700560/greater-fear-of-reinjury-is-related-to-stiffened-jump-landing-biomechanics-and-muscle-activation-in-women-after-acl-reconstruction
#11
Stephanie M Trigsted, Dane B Cook, Kristen A Pickett, Lisa Cadmus-Bertram, Warren R Dunn, David R Bell
PURPOSE: Fear of reinjury is an important factor in determining who returns to sport following anterior cruciate ligament reconstruction (ACLR). Evidence from other musculoskeletal injuries indicates fear of reinjury may be related to stiffened movement patterns observed in individuals following ACLR. The relationship between fear of reinjury and performance on dynamic tasks, however, has not been investigated. Therefore, the purpose of this study was to investigate the relationship between fear of reinjury and jump-landing biomechanics...
April 26, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29671383/sport-specific-biomechanical-responses-to-an-acl-injury-prevention-programme-a-randomised-controlled-trial
#12
Jeffrey B Taylor, Kevin R Ford, Randy J Schmitz, Scott E Ross, Terry A Ackerman, Sandra J Shultz
Anterior cruciate ligament (ACL) injury prevention programmes have not been as successful at reducing injury rates in women's basketball as in soccer. This randomised controlled trial (ClinicalTrials.gov #NCT02530333) compared biomechanical adaptations in basketball and soccer players during jump-landing activities after an ACL injury prevention programme. Eighty-seven athletes were cluster randomised into intervention (6-week programme) and control groups. Three-dimensional biomechanical analyses of drop vertical jump (DVJ), double- (SAG-DL) and single-leg (SAG-SL) sagittal, and double- (FRONT-DL) and single-leg (FRONT-SL) frontal plane jump landing tasks were tested before and after the intervention...
April 19, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29671010/-biomechanical-screening-for-injury-prevention-the-importance-of-3d-motion-analysis-in-high-performance-sports
#13
REVIEW
H Dewitz, B Yildirim, P Klein
Standardized clinical diagnostic procedures cannot assess the functionality of the anatomical structures in sport-specific movement. Biomechanical screening is able to detect deficits but is not sufficiently and objectively precise with the current clinical examination tools including conventional imaging techniques. The fields of use of functional testing methods are versatile and range from injury prevention analysis, screening during rehabilitation phases up to the return-to-play decision. Using simple musculoskeletal function analysis it is difficult to assess the risk of injuries...
April 18, 2018: Der Unfallchirurg
https://www.readbyqxmd.com/read/29662914/ligament-strain-response-between-lower-extremity-contralateral-pairs-during-in-vitro-landing-simulation
#14
April L McPherson, Nathanial A Bates, Nathan D Schilaty, Christopher V Nagelli, Aaron J Krych, Timothy E Hewett
Background: Limb asymmetries, as determined through in vivo biomechanical measures, are known risk factors for anterior cruciate ligament (ACL) injury. Previous cadaveric studies have shown a lack of significant differences in ligament strain between contralateral lower extremities when identical kinematics were simulated on specimens. Recent methodological developments have applied in vivo knee kinetics to exert landing forces on cadaveric lower extremities to mimic ACL injury events, but it is unknown whether contralateral limbs fail in a consistent manner during impact simulator testing...
April 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29650339/a-force-profile-analysis-comparison-between-functional-data-analysis-statistical-parametric-mapping-and-statistical-non-parametric-mapping-in-on-water-single-sculling
#15
REVIEW
John Warmenhoven, Andrew Harrison, Mark A Robinson, Jos Vanrenterghem, Norma Bargary, Richard Smith, Stephen Cobley, Conny Draper, Cyril Donnelly, Todd Pataky
OBJECTIVES: To examine whether the Functional Data Analysis (FDA), Statistical Parametric Mapping (SPM) and Statistical non-Parametric Mapping (SnPM) hypothesis testing techniques differ in their ability to draw inferences in the context of a single, simple experimental design. DESIGN: The sample data used is cross-sectional (two-sample gender comparison) and evaluation of differences between statistical techniques used a combination of descriptive and qualitative assessments...
March 21, 2018: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29613821/lower-extremity-kinematics-differed-between-a-controlled-drop-jump-and-volleyball-takeoffs
#16
Bradley S Beardt, Myranda R McCollum, Taylour J Hinshaw, Jacob S Layer, Margaret A Wilson, Qin Zhu, Boyi Dai
Previous studies utilizing jump-landing biomechanics to predict anterior cruciate ligament injuries have shown inconsistent findings. The purpose of this study was to quantify the differences and correlations in jump-landing kinematics between a drop-jump, a controlled volleyball-takeoff, and a simulated-game volleyball-takeoff. Seventeen female volleyball players performed these three tasks on a volleyball court while three-dimensional kinematic data were collected by three calibrated camcorders. Participants demonstrated significantly increased jump height, shorter stance time, increased time differences in initial contact between two feet, increased knee and hip flexion at initial contact and decreased peak knee and hip flexion for both left and right legs, and decreased knee-ankle distance ratio at the lowest height of mid-hip for the two volleyball-takeoffs compared with the drop-jump (p < 0...
April 3, 2018: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/29602475/concurrent-validation-of-an-inertial-measurement-system-to-quantify-kicking-biomechanics-in-four-football-codes
#17
Stephanie Blair, Grant Duthie, Sam Robertson, William Hopkins, Kevin Ball
Wearable inertial measurement systems (IMS) allow for three-dimensional analysis of human movements in a sport-specific setting. This study examined the concurrent validity of a IMS (Xsens MVN system) for measuring lower extremity and pelvis kinematics in comparison to a Vicon motion analysis system (MAS) during kicking. Thirty footballers from Australian football (n = 10), soccer (n = 10), rugby league and rugby union (n = 10) clubs completed 20 kicks across four conditions. Concurrent validity was assessed using a linear mixed-modelling approach, which allowed the partition of between and within-subject variance from the device measurement error...
March 21, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29602303/hop-distance-symmetry-does-not-indicate-normal-landing-biomechanics-in-adolescent-athletes-with-recent-anterior-cruciate-ligament-reconstruction
#18
Tishya A L Wren, Nicole M Mueske, Christopher H Brophy, J Lee Pace, Mia J Katzel, Bianca R Edison, Curtis D VandenBerg, Tracy L Zaslow
Study Design Retrospective cohort. Background Return to sport (RTS) protocols after anterior cruciate ligament reconstruction (ACLR) often include assessment of hop distance symmetry. However, it is unclear if movement deficits are present regardless of hop symmetry. Objectives To assess biomechanics and symmetry of adolescent athletes following ACLR during a single leg hop for distance. Methods Forty-six patients with ACLR (5-12 months post-surgery; 27 female; age 15.6, SD 1.7 years) were classified as asymmetric (operative limb hop distance <90% of non-operative limb; n=17) or symmetric (n=29)...
March 30, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29584523/brain-behavior-mechanisms-for-the-transfer-of-neuromuscular-training-adaptions-to-simulated-sport-initial-findings-from-the-train-the-brain-project
#19
Dustin R Grooms, Adam W Kiefer, Michael A Riley, Jonathan D Ellis, Staci Thomas, Katie Kitchen, Christopher DiCesare, Scott Bonnette, Brooke Gadd, Kim D Barber Foss, Weihong Yuan, Paula Silva, Ryan Galloway, Jed Diekfuss, James Leach, Kate Berz, Gregory D Myer
CONTEXT: A limiting factor for reducing anterior cruciate ligament (ACL) injury risk is ensuring that the movement adaptions made during the prevention program transfer to sport-specific activity. Virtual reality provides a mechanism to assess transferability and neuroimaging provides a means to assay the neural processes allowing for such skill transfer. OBJECTIVE: To determine the neural mechanisms for injury risk reducing biomechanics transfer to sport after ACL injury prevention training...
March 27, 2018: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/29581141/risk-factors-for-and-prevention-of-shoulder-injuries-in-overhead-sports-a-systematic-review-with-best-evidence-synthesis
#20
REVIEW
Martin Asker, Hannah L Brooke, Markus Waldén, Ulrika Tranaeus, Fredrik Johansson, Eva Skillgate, Lena W Holm
OBJECTIVE: To assess the evidence for risk factors and prevention measures for shoulder injuries in overhead sports. DESIGN: Systematic review with best-evidence synthesis. DATA SOURCES: Medline (Ovid), PubMed (complementary search), Embase (Elsevier), Cochrane (Wiley), SPORTDiscus (Ebsco) and Web of Science Core Collection (Thomson Reuters), from 1 January 1990 to 15 May 2017. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Randomised controlled trials, cohort studies and case-control studies on risk factors or prevention measures for shoulder injuries in overhead sports...
March 26, 2018: British Journal of Sports Medicine
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