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Exercise Performance

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https://www.readbyqxmd.com/read/29793014/calf-muscle-oxygen-saturation-during-six-minute-walk-test-and-its-relationship-with-walking-impairment-in-symptomatic-peripheral-artery-disease
#1
Aluísio Andrade-Lima, Gabriel G Cucato, Wagner J R Domingues, Antônio H Germano-Soares, Bruno R Cavalcante, Marilia A Correia, Glauco F Saes, Nelson Wolosker, Andrew W Gardner, Antônio E Zerati, Raphael M Ritti-Dias
OBJECTIVE: Impaired microcirculation is associated with poor walking capacity in symptomatic peripheral artery disease (PAD) patients during treadmill test, however, this test does not simulate the efforts of daily walking of these patients. Thus, the aim of the study was to describe the microcirculation responses during six-minute walk test (6MWT) and to analyze the relationship between microcirculation indicators and walking impairment in symptomatic PAD patients. METHODS: Thirty-four patients were included (mean age = 67...
May 21, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29792554/effect-of-acetazolamide-and-methazolamide-on-diaphragm-and-dorsiflexor-fatigue-a-randomized-controlled-trial
#2
Paolo B Dominelli, Chris J McNeil, Tyler Dennis Vermeulen, Troy J R Stuckless, Courtney V Brown, Giulio S Dominelli, Erik Richard Swenson, Lucas J Teppema, Glen Edward Foster
Acetazolamide, a carbonic anhydrase (CA) inhibitor used clinically and to prevent acute mountain sickness, worsens skeletal muscle fatigue in animals and humans. In animals, methazolamide, a methylated analogue of acetazolamide and an equally potent CA inhibitor, reportedly exacerbates fatigue less than acetazolamide. Accordingly, we sought to determine, in humans, if methazolamide would attenuate diaphragm and dorsiflexor fatigue compared to acetazolamide. Healthy men (dorsiflexor: n=12; diaphragm: n=7) performed fatiguing exercise on three occasions, after ingesting acetazolamide (250 mg three times a day) and then in random order, methazolamide (100 mg twice a day) or placebo for 48 h...
May 24, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29792299/a-simple-evidence-based-approach-to-help-guide-diagnosis-of-heart-failure-with-preserved-ejection-fraction
#3
Yogesh N V Reddy, Rickey E Carter, Masaru Obokata, Margaret M Redfield, Barry A Borlaug
Background -Diagnosis of heart failure with preserved ejection fraction (HFpEF) is challenging in euvolemic patients with dyspnea, and no evidence-based criteria are available. We sought to develop and then validate non-invasive diagnostic criteria that could be used to estimate the likelihood that HFpEF is present among patients with unexplained dyspnea in order to guide further testing. Methods -Consecutive patients with unexplained dyspnea referred for invasive hemodynamic exercise testing were retrospectively evaluated...
May 23, 2018: Circulation
https://www.readbyqxmd.com/read/29792061/diet-and-exercise-for-preeclampsia-prevention-in-overweight-and-obese-pregnant-women-systematic-review-and-meta-analysis
#4
Argyro Syngelaki, Miguel Sequeira Campos, Stephanie Roberge, Walkyria Andrade, Kypros H Nicolaides
OBJECTIVE: To investigate the effect of diet and/or exercise in overweight or obese pregnant women on the risk of preeclampsia. METHODS: We performed a systematic review and meta-analysis of randomized controlled trials examining the effect of diet and/or exercise interventions in overweight and obese pregnant women on the risk of preeclampsia (PE) and hypertensive disorders. We completed a literature search through PubMed, Embase, Cinahl, Web of science, Cochrane CENTRAL Library from their earliest entries to November 2017 and from references of other systematic reviews...
May 23, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29791970/effect-of-high-intensity-resistance-circuit-based-training-in-hypoxia-on-aerobic-performance-and-repeat-sprint-ability
#5
Domingo J Ramos-Campo, Ismael Martínez-Guardado, Guillermo Olcina, Cristian Marín-Pagán, Francisco J Martínez-Noguera, Jorge Carlos-Vivas, Pedro E Alcaraz, Jacobo A Rubio-Arias
Recent acute studies have shown that high-intensity resistance circuit-based (HRC) training in hypoxia increases metabolic stress. However, no intervention studies have yet proven their effectiveness. This study aimed to analyse the effect of 8 weeks of HRC in hypoxia on aerobic performance, resting energy expenditure (REE), repeat sprint ability (RSA) and haematological variables. Twenty-eight subjects were assigned to hypoxia (FiO2 =15%; HRChyp : n=15; age: 24.6±6.8 years; height: 177.4±5.9 cm; weight: 74...
May 23, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29791847/neutrophils-provide-a-favorable-il-1-mediated-immunometabolic-niche-that-primes-glut4-translocation-and-performance-in-skeletal-muscles
#6
Masahiro Tsuchiya, Shigenori Sekiai, Hiroyasu Hatakeyama, Masashi Koide, Chayanit Chaweewannakorn, Fukie Yaoita, Koichi Tan-No, Keiichi Sasaki, Makoto Watanabe, Shunji Sugawara, Yasuo Endo, Eiji Itoi, Yoshihiro Hagiwara, Makoto Kanzaki
Metabolic immunomodulation involving IL-1 has been investigated for unfavorable metabolic effects, including obesity, but a potentially favorable role for IL-1 remains unclear. Here, we find mechanistic interactions between working skeletal muscles and locally recruited neutrophils expressing IL-1β, which supports muscle performance through priming exercise-dependent GLUT4 translocation. Thus, during exercise, both IL-1α/β-deficient and neutrophil-depleted mice similarly exhibit increased fatigability associated with impaired muscle glucose homeostasis due to GLUT4 dysregulation...
May 22, 2018: Cell Reports
https://www.readbyqxmd.com/read/29791649/bouts-of-exercise-elicit-discordant-testosterone-cortisol-ratios-in-runners-and-non-runners
#7
Thiago Paes de Barros De Luccia, José Eduardo Soubhia Natali, Alexandre Moreira, José Guilherme Chaui-Berlinck, José Eduardo Pereira Wilken Bicudo
OBJECTIVE: The testosterone:cortisol ratio (T:C) is suggested to be used in order to examine whether physical exercise generates either a "catabolic environment" or an "anabolic environment". The present study aims to evaluate the acute time-course profile of cortisol and testosterone due to an episode of physical exercise. A biphasic profile in the T:C ratio response was hypothesized. MATERIALS AND METHODS: Morning sessions of treadmill running at two different intensities (Heart Rate at 65% and 80% of the maximum cardiac reserve) were performed by 6 male non-runners (NR) and 12 trained male runners (subdivided into trained runners T1 and T2)...
May 17, 2018: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29791605/athlete-s-heart-in-a-brazilian-paralympic-judo-team-case-series-study
#8
Japy Angelini Oliveira Filho, Maria Beatriz Monteiro Barros, Ana Fátima Salles, Leandro Santini Echenique, Orlando Campos Filho, Rui Manoel Santos Póvoa
BACKGROUND: Athlete's heart is a term describing the cardiovascular effects of long-term conditioning among highly trained athletes. It is a variation of normal standards. DESIGN AND SETTING: Case series study at the cardiology division of a public university hospital. METHODS: We studied 14 visually handicapped paralympic athletes (8 men) in the national judo team. They were 26.3 ± 6.4 years old, with body mass index 25 ± 14, and had been practicing judo for 9...
March 2018: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/29791580/influence-of-aerobic-training-on-the-mechanics-of-ventricular-contraction-after-acute-myocardial-infarction-a-pilot-study
#9
Giovani Luiz De Santi, Henrique Turin Moreira, Eduardo Elias Vieira de Carvalho, Júlio César Crescêncio, André Schmidt, José Antônio Marin-Neto, Lourenço Gallo-Júnior
The study of myocardial contractility, based on the new anatomical concepts that govern cardiac mechanics, represents a promising strategy of analysis of myocardial adaptations related to physical training in the context of post-infarction. We investigated the influence of aerobic training on physical capacity and on the evaluation parameters of left ventricular contraction mechanics in patients with myocardial infarction. Thirty-one patients (55.1 ± 8.9 years) who had myocardial infarction in the anterior wall were prospectively investigated in three groups: interval training group (ITG) (n = 10), moderate training group (MTG) n = 10) and control group (CG) (n = 10)...
April 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29791076/effects-of-endurance-training-on-hippocampus-dj-1-cb-2-and-blood-glucose-concentration-in-diabetic-rats
#10
Mohammad Kurd, Vahid Valipour Dehnou, Seyed Asadollah Tavakoli, Daniel E Gahreman
AIMS: To investigate the effect of endurance training on Hippocampus DJ-1 and CB2 protein and blood glucose concentration in diabetic rats. MATERIALS AND METHODS: Thirty-two rats were randomly divided into Diabetic (D), Diabetic and Exercise (DE), Exercise (E), and Control (C) groups. The endurance training was performed five times per week for six weeks. The hippocampus DJ-1 and CB2 were measured using an ELISA method. RESULTS: The level of DJ-1 in D group was significantly higher than other groups (p ≤ 0...
May 23, 2018: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29790430/improvement-of-cellular-health-indicators-and-muscle-quality-in-older-women-with-different-resistance-training-volumes
#11
Paolo M Cunha, Crisieli M Tomeleri, Matheus A do Nascimento, João Pedro Nunes, Melissa Antunes, Hellen C G Nabuco, Ygor Quadros, Edilaine F Cavalcante, Jerry L Mayhew, Luís B Sardinha, Edilson S Cyrino
The main purpose of this study was to compare the effects of resistance training (RT) performed with different training volumes on phase angle (PhA), body water components, and muscle quality (MQ) in untrained older adult women. A second purpose was to assess the relationship between PhA and MQ. Sixty-two older adult women (68.6 ± 5.0 years, 65.2 ± 13.3 kg, 156.1 ± 6.2 cm) were randomly assigned into one of the three groups: two training groups performed either 1 set (G1S) or 3 sets (G3S), or a control group (CG)...
May 23, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29790228/evidence-based-dentistry-skill-acquisition-by-second-year-dental-students
#12
T A Marshall, S C McKernan, C L Straub-Morarend, S Guzman-Armstrong, L Marchini, N Q Handoo, M A Cunningham
INTRODUCTION: Identification and assessment of Evidence-based dentistry (EBD) outcomes have been elusive. Our objective was to describe EBD skill acquisition during the second (D2) year of pre-doctoral dental education and student competency at the end of the year. METHODS: The first and fourth (final) curricular-required EBD Exercises (ie, application of the first 4 steps of the 5-Step evidence-based practice process applied to a real or hypothetical situation) completed by D2 students (n = 151) during 2014-2015 and 2015-2016 were evaluated to measure skill acquisition through use of a novel rubric with measures of performance from novice to expert...
May 22, 2018: European Journal of Dental Education: Official Journal of the Association for Dental Education in Europe
https://www.readbyqxmd.com/read/29790224/left-atrial-compression-and-right-ventricular-outflow-tract-diameter-on-echocardiography-are-independently-associated-with-exercise-capacity-in-patients-with-large-hiatal-hernia
#13
Christopher Naoum, Leonard Kritharides, Gregory L Falk, David Martin, John Yiannikas
INTRODUCTION: Large hiatal hernia (HH) is often associated with left atrial (LA) compression, anteroposterior cardiac compression (manifesting as reduced right ventricular outflow tract (RVOT) diameter), and left ventricular (LV) compression (manifesting as systolic paradoxical outward motion (LV-PM) of the posterobasal LV segment). Exercise impairment, also common in this population, improves following HH surgery. We aimed to identify echocardiographic parameters independently associated with exercise impairment due to HH-mediated cardiogenic compression...
May 2018: Echocardiography
https://www.readbyqxmd.com/read/29790207/the-repeated-bout-effect-can-occur-without-mechanical-and-neuromuscular-changes-after-a-bout-of-eccentric-exercise
#14
Patricio A Pincheira, Ben W Hoffman, Andrew G Cresswell, Timothy J Carroll, Nicholas A T Brown, Glen A Lichtwark
Changes in muscle fascicle mechanics have been postulated to underpin the repeated bout effect (RBE) observed following exercise-induced muscle damage (EIMD). However, in the medial gastrocnemius (MG), mixed evidence exists on whether fascicle stretch amplitude influences the level of EIMD, thus questioning whether changes in fascicle mechanics underpin the RBE. An alternative hypothesis is that neural adaptations contribute to the RBE in this muscle. The aim of this study was to investigate neuromechanical adaptations during and after repeated bouts of a highly controlled muscle lengthening exercise that aimed to maximise EIMD in MG...
May 23, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29790034/left-atrial-myocardial-dysfunction-after-chronic-abuse-of-anabolic-androgenic-steroids-a-speckle-tracking-echocardiography-analysis
#15
Antonello D'Andrea, Juri Radmilovic, Stefano Caselli, Andreina Carbone, Raffaella Scarafile, Simona Sperlongano, Gianpaolo Tocci, Tiziana Formisano, Francesca Martone, Biagio Liccardo, Michele D'Alto, Eduardo Bossone, Maurizio Galderisi, Paolo Golino
Anabolic-androgenic steroids (AAS) are used by power athletes to improve performance. However, the real effects of the chronic consumption of AAS on cardiovascular structures are subjects of intense debate. To detect by speckle tracking echocardiography (STE) underlying left atrial (LA) dysfunction in athletes abusing AAS and assess possible correlation between LA myocardial function and exercise capacity during cardiopulmonary stress test. 65 top-level competitive bodybuilders were selected (45 males), including 35 athletes misusing AAS for at least 5 years (users), 30 anabolic-free bodybuilders (non-users), compared to 40 age- and sex-matched healthy sedentary controls...
May 22, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29789977/effect-of-missing-data-on-multitask-prediction-methods
#16
Antonio de la Vega de León, Beining Chen, Valerie J Gillet
There has been a growing interest in multitask prediction in chemoinformatics, helped by the increasing use of deep neural networks in this field. This technique is applied to multitarget data sets, where compounds have been tested against different targets, with the aim of developing models to predict a profile of biological activities for a given compound. However, multitarget data sets tend to be sparse; i.e., not all compound-target combinations have experimental values. There has been little research on the effect of missing data on the performance of multitask methods...
May 22, 2018: Journal of Cheminformatics
https://www.readbyqxmd.com/read/29789801/exercise-prevents-diaphragm-wasting-induced-by-cigarette-smoke-through-modulation-of-antioxidant-genes-and-metalloproteinases
#17
Gracielle Vieira Ramos, Alessandra Choqueta de Toledo-Arruda, Clara Maria Pinheiro-Dardis, Camila Liyoko Suehiro, Thiago Luiz de Russo, Rodolfo Paula Vieira, Milton Arruda Martins, Tania Fátima Salvini, João Luiz Quagliotti Durigan
Background: The present study aimed to analyze the effects of physical training on an antioxidant canonical pathway and metalloproteinases activity in diaphragm muscle in a model of cigarette smoke-induced chronic obstructive pulmonary disease (COPD). Methods: Male mice were randomized into control, smoke, exercise, and exercise + smoke groups, which were maintained in trial period of 24 weeks. Gene expression of kelch-like ECH-associated protein 1; nuclear factor erythroid-2 like 2; and heme-oxygenase1 by polymerase chain reaction was performed...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29789415/acute-effects-of-different-types-of-resistance-training-on-cardiac-autonomic-modulation-in-copd
#18
Franciele M Vanderlei, Fernando Zandonadi, Fabiano Franciso de Lima, Bruna S A Silva, Ana Paula C F Freire, Dionei Ramos, Ercy Mara C Ramos
BACKGROUND: An exercise modality that has been gaining significant importance in the rehabilitation of subjects with COPD is resistance training. When considering that patients with COPD present alterations in autonomic cardiac modulation caused by the disease itself, it is necessary to investigate the behavior of the autonomic nervous system in relation to this type of exercise. Thus, the objective of this study was to compare the acute effects of resistance training with elastic tubes, elastic bands, and conventional weightlifitng on the behavior of cardiac autonomic modulation in post-exercise recovery in subjects with COPD...
May 22, 2018: Respiratory Care
https://www.readbyqxmd.com/read/29789413/best-protocol-for-the-sit-to-stand-test-in-subjects-with-copd
#19
Andrea A Morita, Gianna W Bisca, Felipe V C Machado, Nidia A Hernandes, Fabio Pitta, Vanessa S Probst
BACKGROUND: Different protocols for the sit-to-stand test (STS) are available for assessing functional capacity in COPD. We sought to correlate each protocol of the STS (ie, the 5-repetition [5-rep STS], the 30-s STS, and the 1-min STS) with clinical outcomes in subjects with COPD. We also aimed to compare the 3 protocols of the STS, to verify their association and agreement, and to verify whether the 3 protocols are able to predict functional exercise capacity and physical activity in daily life (PADL)...
May 22, 2018: Respiratory Care
https://www.readbyqxmd.com/read/29789302/fractional-flow-reserve-and-instantaneous-wave-free-ratio-as-predictors-of-the-placebo-controlled-response-to-percutaneous-coronary-intervention-in-stable-single-vessel-coronary-artery-disease-physiology-stratified-analysis-of-orbita
#20
Rasha Al-Lamee, James P Howard, Matthew J Shun-Shin, David Thompson, Hakim-Moulay Dehbi, Sayan Sen, Sukhjinder Nijjer, Ricardo Petraco, John Davies, Thomas Keeble, Kare Tang, Iqbal S Malik, Christopher Cook, Yousif Ahmad, Andrew S P Sharp, Robert Gerber, Christopher Baker, Raffi Kaprielian, Suneel Talwar, Ravi Assomull, Graham Cole, Niall G Keenan, Gajen Kanaganayagam, Joban Sehmi, Roland Wensel, Frank E Harrell, Jamil Mayet, Simon A Thom, Justin E Davies, Darrel P Francis
BACKGROUND : There are no data on how fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are associated with the placebo-controlled efficacy of percutaneous coronary intervention (PCI) in stable single-vessel coronary artery disease. METHODS : We report the association between prerandomization invasive physiology within ORBITA (Objective Randomised Blinded Investigation With Optimal Medical Therapy of Angioplasty in Stable Angina), a placebo-controlled trial of patients who have stable angina with angiographically severe single-vessel coronary disease clinically eligible for PCI...
May 22, 2018: Circulation
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