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https://www.readbyqxmd.com/read/29470970/comparisons-between-histology-and-optical-coherence-tomography-angiography-of-the-periarterial-capillary-free-zone
#1
Chandrakumar Balaratnasingam, Dong An, Yoichi Sakurada, Cecilia S Lee, Aaron Y Lee, Ian L McAllister, K Bailey Freund, Marinko Sarunic, Dao-Yi Yu
PURPOSE: To use the capillary-free zone along retinal arteries, a physiologic area of superficial avascularization, as an anatomic paradigm to investigate the reliability of optical coherence tomographic angiography (OCTA) for visualizing the deep retinal circulation. DESIGN: Validity analysis and laboratory investigation. METHODS: Five normal human donor eyes (mean age 69.8 years) were perfusion-labelled with endothelial antibodies and the capillary networks of the perifovea were visualized using confocal scanning laser microscopy...
February 19, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29470622/genetic-dissection-of-wheat-panicle-traits-using-linkage-analysis-and-a-genome-wide-association-study
#2
Kai Liu, Xiaoxiao Sun, Tangyuan Ning, Xixian Duan, Qiaoling Wang, Tongtong Liu, Yuling An, Xin Guan, Jichun Tian, Jiansheng Chen
Coincident regions on chromosome 4B for GW, on 5A for SD and TSS, and on 3A for SL and GNS were detected through an integration of a linkage analysis and a genome-wide association study (GWAS). In addition, six stable QTL clusters on chromosomes 2D, 3A, 4B, 5A and 6A were identified with high PVE% on a composite map. The panicle traits of wheat, such as grain number per spike and 1000-grain weight, are closely correlated with grain yield. Superior and effective alleles at loci related to panicles developments play a crucial role in the progress of molecular improvement in wheat yield breeding...
February 22, 2018: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/29469657/direct-mass-spectrometric-characterization-of-disulfide-linkages
#3
Xiaoyan Guan, Le Zhang, Jette Wypych
Disulfide linkage is critical to protein folding and structural stability. The location of disulfide linkages for antibodies is routinely discovered by comparing the chromatograms of the reduced and non-reduced peptide mapping with location identification confirmed by collision-induced dissociation (CID) mass spectrometry (MS)/MS. However, CID product spectra of disulfide-linked peptides can be difficult to interpret, and provide limited information on the backbone region within the disulfide loop. Here, we applied an electron-transfer dissociation (ETD)/CID combined fragmentation method that identifies the disulfide linkage without intensive LC comparison, and yet maps the disulfide location accurately...
February 22, 2018: MAbs
https://www.readbyqxmd.com/read/29467776/genome-wide-association-analyses-identify-qtl-hotspots-for-yield-and-component-traits-in-durum-wheat-grown-under-yield-potential-drought-and-heat-stress-environments
#4
Sivakumar Sukumaran, Matthew P Reynolds, Carolina Sansaloni
Understanding the genetic bases of economically important traits is fundamentally important in enhancing genetic gains in durum wheat. In this study, a durum panel of 208 lines (comprised of elite materials and exotics from the International Maize and Wheat Improvement Center gene bank) were subjected to genome wide association study (GWAS) using 6,211 DArTseq single nucleotide polymorphisms (SNPs). The panel was phenotyped under yield potential (YP), drought stress (DT), and heat stress (HT) conditions for 2 years...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29466274/dissociated-time-course-of-recovery-between-strength-and-power-after-isoinertial-resistance-loading-in-rugby-union-players
#5
Rodney A Kennedy, David Drake
Kennedy, RA and Drake, D. Dissociated time course of recovery between strength and power after isoinertial resistance loading in rugby union players. J Strength Cond Res 32(3): 748-755, 2018-There is a substantial amount of research on the responses to isometric and eccentric loading. However, only a paucity of literature exists on the responses to isoinertial loading, especially in trained athletic populations using realistic loading protocols. The purpose of this study was to examine the acute neuromuscular response to a bout of isoinertial resistance loading in elite rugby players...
March 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29466246/modified-aging-of-elite-athletes-revealed-by-analysis-of-epigenetic-age-markers
#6
Magdalena Spólnicka, Ewelina Pośpiech, Jakub Grzegorz Adamczyk, Ana Freire-Aradas, Beata Pepłońska, Renata Zbieć-Piekarska, Żanetta Makowska, Anna Pięta, Maria Victoria Lareu, Christopher Phillips, Rafał Płoski, Cezary Żekanowski, Wojciech Branicki
Recent progress in epigenomics has led to the development of prediction systems that enable accurate age estimation from DNA methylation data. Our objective was to track responses to intense physical exercise of individual age-correlated DNA methylation markers and to infer their potential impact on the aging processes. The study showed accelerated DNA hypermethylation for two CpG sites in TRIM59 and KLF14 . Both markers predicted the investigated elite athletes to be several years older than controls and this effect was more substantial in subjects involved in power sports...
February 15, 2018: Aging
https://www.readbyqxmd.com/read/29466098/comparing-global-positioning-system-gps-and-global-navigation-satellite-system-gnss-measures-of-team-sport-movements
#7
Benjamin M Jackson, Ted Polglaze, Brian Dawson, Trish King, Peter Peeling
PURPOSE: To compare data from conventional GPS and new GNSS-enabled tracking devices, and to examine the inter-unit reliability of GNSS devices. METHODS: Inter-device differences between 10 Hz GPS and GNSS devices were examined during laps (n=40) of a simulated game circuit (SGC) and during elite hockey matches (n=21); GNSS inter-unit reliability was also examined during the SGC laps. Differences in distance values and measures in three velocity categories (low <3 m...
February 21, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29466090/enhanced-external-counterpulsation-and-short-term-recovery-from-high-intensity-interval-training
#8
Pedro L Valenzuela, Guillermo Sánchez-Martínez, Elaia Torrentegi, Zigor Montalvo, Alejandro Lucia, Pedro de la Villa
PURPOSE: The use of enhanced external counter-pulsation (EECP) as a recovery strategy has increased in recent years owing to its benefits in the clinical setting. However, its claimed effectiveness for the enhancement of exercise recovery has not been analyzed in athletes. The aim of this study was to determine the effectiveness of EECP on short-term recovery after a fatiguing exercise bout. METHODS: 12 elite junior triathletes (16 ± 2 years) participated in this cross-over counterbalanced study...
February 21, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29466071/dynamics-of-the-metabolic-response-during-a-competitive-100-m-freestyle-in-elite-male-swimmers
#9
Philippe Hellard, Robin Pla, Ferran A Rodríguez, David Simbana, David B Pyne
PURPOSE: To compare the dynamics of V̇O2 , blood lactate ([La]b ), total energy expenditure (Etot ), and contributions of the aerobic (Eaer ), alactic anaerobic (Ean,al ) and lactic anaerobic (Ean,lac ) metabolic energy pathways over four consecutive 25-m laps (L0-25 , L25-50 , L50-75 , L75-100 ) of a 100-m maximal freestyle swim. METHODS: Elite swimmers comprising 26 juniors (16 ± 1 y) and 23 seniors (24 ± 5 y) performed 100 m at maximal speed, and then three trials (25, 50 and 75 m) at the same pace as that of the 100 m...
February 21, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29466055/nature-vs-nurture-have-performance-gaps-between-men-and-women-reached-an-asymptote
#10
Mindy Millard-Stafford, Ann E Swanson, Matthew T Wittbrodt
Men outperform women in sports requiring muscular strength and/or endurance, but the relative influence of "nurture" versus "nature" remains difficult to quantify. Performance gaps between elite men and women are well-documented using world records in second, centimeter or kilogram sports. However, this approach is biased by global disparity in reward structures and opportunities for women. Despite policies enhancing female participation (Title IX legislation), USA women only closed performance gaps by 2 and 5% in Olympic Trial swimming and running, respectively, from 1972 to 1980 (with no change thereafter through 2016)...
February 21, 2018: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29465845/a-study-to-assess-the-prevalence-of-exercise-induced-bronchoconstriction-in-inter-county-hurling
#11
E B Hunt, B Murphy, C Murphy, T Crowley, O Cronin, S Hay, M Stack, B Bowen, N J Ronan, E Greene, J A Eustace, B J Plant, D M Murphy
Exercise-Induced Bronchoconstriction (EIB) is an acute, transient airway narrowing occurring after exercise which may impact athletic performance. Studies report 10% of the general population and up to 90% of asthmatics experience EIB. Ninety-two players from three elite hurling squads underwent a spirometric field-based provocation test with real-time heart rate monitoring and lactate measurements to ensure adequate exertion. Players with a new diagnosis of EIB and those with a negative field-test but with a previous label of EIB or asthma underwent further reversibility testing and if negative, methacholine challenge...
December 18, 2017: Irish Medical Journal
https://www.readbyqxmd.com/read/29465607/the-efficacy-of-heart-rate-variability-in-tracking-travel-and-training-stress-in-youth-female-rowers-a-preliminary-study
#12
Julian D Egan-Shuttler, Rohan Edmonds, Stephen J Ives
(248 words)Heart rate (HR) variability (HRV) is a reliable indicator of cardiac parasympathetic activity and has been used in athletic populations to measure training adaptations. To date, there is limited research showing whether HRV is practical in youth female athletes and rowers during short periods of overload training. PURPOSE: The purpose of this study was to evaluate the practicality of HRV in documenting training responses during a period of overload training in youth female rowers...
February 15, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29463359/prophylactic-ankle-braces-and-the-kinematics-and-kinetics-of-half-squat-parachute-landing
#13
Di Wu, Chao Zheng, Ji Wu, Tan Hu, Rongrong Huang, Lizhen Wang, Yubo Fan
INTRODUCTION: The objective of the study was to investigate the effects of dropping heights and prophylactic ankle braces on ankle joint biomechanics during half-squat parachute landing from two different heights. METHODS: There were 30 male elite paratroopers with formal parachute landing training and more than 2 yr of parachute jumping experience who were recruited for this study. The subjects tested three different ankle brace conditions (no-brace, elastic brace, semirigid brace)...
February 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29463034/chronic-ketogenic-low-carbohydrate-high-fat-diet-has-minimal-effects-on-acid-base-status-in-elite-athletes
#14
Amelia J Carr, Avish P Sharma, Megan L Ross, Marijke Welvaert, Gary J Slater, Louise M Burke
Although short (up to 3 days) exposure to major shifts in macronutrient intake appears to alter acid-base status, the effects of sustained (>1 week) interventions in elite athletes has not been determined. Using a non-randomized, parallel design, we examined the effect of adaptations to 21 days of a ketogenic low carbohydrate high fat (LCHF) or periodized carbohydrate (PCHO) diet on pre- and post-exercise blood pH, and concentrations of bicarbonate (HCO₃- ) and lactate (La- ) in comparison to a high carbohydrate (HCHO) control...
February 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29462182/exercise-induced-cardiac-remodeling-in-non-elite-endurance-athletes-comparison-of-2-tiered-and-4-tiered-classification-of-left-ventricular-hypertrophy
#15
Lukas D Trachsel, Christoph P Ryffel, Stefano De Marchi, Christian Seiler, Nicolas Brugger, Prisca Eser, Matthias Wilhelm
BACKGROUND: Long-term endurance sport practice leads to eccentric left ventricular hypertrophy (LVH). We aimed to compare the new 4-tiered classification (4TC) for LVH with the established 2-tiered classification (2TC) in a cohort of normotensive non-elite endurance athletes. METHODS: Male participants of a 10-mile race were recruited and included when blood pressure (BP) was normal (<140/90 mmHg). Phenotypic characterization of LVH was based on relative wall thickness (2TC), and on LV concentricity2/3 (LV mass/end-diastolic volume [LVM/EDV]2/3) plus LVEDV index (4TC)...
2018: PloS One
https://www.readbyqxmd.com/read/29461419/morphological-and-physical-fitness-profile-of-young-female-sprint-kayakers
#16
Daniel López-Plaza, Fernando Alacid, Jacobo Ángel Rubio, Pedro Ángel López-Miñarro, José María Muyor, Pedro Manonelles
Traditionally, physical and anthropometrical profiles of the most successful kayak athletes have been identified in male kayakers. This study attempted to identify the differences in morphology and fitness level of two performance-based groups of young elite female paddlers. Eighty-six female kayakers, aged 13.62 ± 0.57 years (mean ± SD) were allocated in two groups (Top-10 and Rest) depending on their ranking in the three Olympic distances (200, 500 and 1000 meters). All subjects underwent a battery of anthropometrical (heights, weight, girths and sum of skinfolds), physical fitness (overhead medicine ball throw, countermovement jump, sit-and-reach test and 20-m multistage shuttle run test) and specific performance assessments (200, 500 and 1000 meters)...
February 14, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29461418/influence-of-biological-maturity-on-the-match-performance-of-8-to-16-year-old-elite-male-youth-soccer-players
#17
Heita Goto, John G Morris, Mary E Nevill
The aim of this study was to examine the influence of biological maturity on match performance in elite youth male soccer players. The participants were 80 Premier League Academy outfield players (8-16 years old). Biological maturity was determined by calculating estimated chronological age at peak height velocity. The U9 and U10 squads played 6-a-side and the U11-U16 squads played 11-a-side inter-academy matches. All matches were analyzed using a 1 Hz Global Positioning System (SPI elite, GPSport, Australia) with squad specific speed zones which were calculated based on 5 m flying sprint speed in the last 5 m of 10 m sprint test...
February 14, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29461415/the-relationship-between-maximal-aerobic-power-and-recovery-in-elite-ice-hockey-players-during-a-simulated-game
#18
Darren Steeves, Phil Campagna
This project investigated whether there was a relationship between maximal aerobic power and the recovery or performance in elite ice hockey players during a simulated hockey game. An on-ice protocol was used to simulate a game of ice hockey. Recovery values were determined by the differences in lactate and heart rate measures. Total distance traveled was also recorded as a performance measure. On two other days, subjects returned and completed a maximal aerobic power test on a treadmill and a maximal lactate test on ice...
February 14, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29461414/validity-and-reliability-of-an-on-court-fitness-test-for-assessing-and-monitoring-aerobic-fitness-in-squash
#19
Carl Alexander James, Florencio Tenllado Vallejo, Melvin Kantebeen, Saro Farra
Current on-court assessments of aerobic fitness in squash are not designed to yield a wealth of physiological data. Moreover, tests may require complex computer equipment or involve simulated racket strokes, which are difficult to standardize at high intensities. This study investigated the validity and reliability of a squash-specific fitness test which can yield both a standalone performance score, as well as pertinent physiological markers such as V[Combining Dot Above]O2max, the lactate turnpoint and oxygen cost, in a sport-specific environment...
February 14, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29461267/a-prospective-transcranial-doppler-ultrasound-based-evaluation-of-the-effects-of-repetitive-subconcussive-head-trauma-on-neurovascular-coupling-dynamics
#20
Alexander D Wright, Jonathan D Smirl, Kelsey Bryk, Michael Jakovac, Paul van Donkelaar
OBJECTIVE: To determine the effects of repetitive subconcussive head trauma on neurovascular coupling (NVC) responses. DESIGN: Prospective cohort study collected between September 2013 and December 2016. SETTING: University laboratory. PARTICIPANTS: One hundred seventy-nine elite, junior-level (age, 19.6 ± 1.5 years) contact sport (ice hockey, American football) athletes recruited for preseason testing. Fifty-two nonconcussed athletes returned for postseason testing...
February 14, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
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