Naveed Ahmed Khan, Adeelah Alvi, Saif Alqassim, Noor Akbar, Bushra Khatoon, Muhammad Kawish, Shaheen Faizi, Muhammad Raza Shah, Bader S Alawfi, Ruqaiyyah Siddiqui
With the emergence of drug-resistance, there is a need for novel anti-bacterials or to enhance the efficacy of existing drugs. In this study, Patuletin (PA), a flavanoid was loaded onto Gallic acid modified Zinc oxide nanoparticles (PA-GA-ZnO), and evaluated for antibacterial properties against Gram-positive (Bacillus cereus and Streptococcus pneumoniae) and Gram-negative (Samonella enterica and Escherichia coli) bacteria. Characterization of PA, GA-ZnO and PA-GA-ZnO' nanoparticles was accomplished utilizing fourier-transform infrared spectroscopy, efficiency of drug entrapment, polydispersity index, zeta potential, size, and surface morphology analysis through atomic force microscopy...
May 6, 2024: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine