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Cardiovascular disease glycemic index

Hidetaka Hamasaki, Yu Kawashima, Hidekatsu Yanai
BACKGROUND: Zinc (Zn) and copper (Cu) may play a pivotal role in the pathogenesis of diabetes and diabetic complications by mediating oxidative stress. Both Zn deficiency and excess of Cu are associated with an increased risk of type 2 diabetes and cardiovascular disease. We aimed to investigate the relationships between serum Zn/Cu ratio and glycemic status, renal function, and metabolic parameters in patients with and without type 2 diabetes. METHODS: We conducted a cross-sectional study on 355 subjects (149 type 2 diabetic and 206 non-diabetic) in whom serum Zn and Cu levels were measured at the same time...
2016: Frontiers in Endocrinology
Sanne N van Munster, Yolanda van der Graaf, Harold W de Valk, Frank L J Visseren, Jan Westerink
AIMS: Strict glycemic control has been shown to reduce cardiovascular events in patients with type 2 diabetes, but may also be associated with increased mortality in certain subgroups. Identifying patients who would benefit from strict glycemic control is therefore paramount. This study aimed to identify patients with T2D that may benefit from lower or higher HbA1c targets, based on readily available patient characteristics. MATERIALS AND METHODS: T2D patients were included from the SMART (Second Manifestations of ARTerial disease) cohort...
November 2, 2016: Diabetes, Obesity & Metabolism
Efraín Rodríguez-Vigil, Migdalia Rodríguez-Chacón, José J Ruiz Valcarcel
OBJECTIVE: The objective of this study was to assess the current relationship between certain demographics and chemical factors, and the risk of cardiovascular complications, within a Puerto Rican population with diabetes mellitus. RESEARCH DESIGN AND METHODS: A total of 2075 patients with diabetes mellitus were retrospectively evaluated to determine the influence of certain demographics and chemical variables on the appearance of cardiovascular complications. A group of demographic and laboratory variables were analyzed...
2016: BMJ Open Diabetes Research & Care
Danxia Yu, Xianglan Zhang, Xiao-Ou Shu, Hui Cai, Honglan Li, Ding Ding, Zhen Hong, Yong-Bing Xiang, Yu-Tang Gao, Wei Zheng, Gong Yang
BACKGROUND: Epidemiologic evidence on dietary carbohydrates and stroke risk remains controversial. Very few prospective cohort studies have been conducted in Asian populations, who usually consume a high-carbohydrate diet and have a high burden of stroke. OBJECTIVE: We examined dietary glycemic index (GI), glycemic load (GL), and intakes of refined and total carbohydrates in relation to risks of total, ischemic, and hemorrhagic stroke and stroke mortality. DESIGN: This study included 64,328 Chinese women, aged 40-70 y, with no history of cardiovascular disease, diabetes, or cancer...
November 2016: American Journal of Clinical Nutrition
Katherine E Joyce, Mary L Biggs, Luc Djoussé, Joachim H Ix, Jorge R Kizer, David S Siscovick, Molly M Shores, Alvin M Matsumoto, Kenneth J Mukamal
CONTEXT: Although sex hormone binding globulin (SHBG) and testosterone (T) have been inversely associated with risk of diabetes, few studies have examined dihydrotestosterone (DHT), a more potent androgen than T, or older adults, whose glycemic pathophysiology differs from younger adults. OBJECTIVE: To determine the associations of SHBG, T, and DHT with insulin resistance and incident diabetes in older adult men. DESIGN: In a prospective cohort study, we evaluated baseline levels of SHBG, T, and DHT using liquid chromatography-tandem mass spectrometry among 852 men in the Cardiovascular Health Study free of diabetes and cardiovascular disease in 1994...
October 12, 2016: Journal of Clinical Endocrinology and Metabolism
Susanna C Larsson, Alicja Wolk
BACKGROUND: Whether consumption of potatoes, which are rich in potassium and have a high glycemic index and glycemic load, is associated with the risk of cardiovascular disease (CVD) is unknown. OBJECTIVE: The aim was to examine the association between potato consumption and risk of total and specific CVD events as well as mortality from CVD in 2 prospective cohorts of Swedish adults, a population with a high consumption of potatoes. DESIGN: Information on potato consumption was available from 69,313 men and women, free of CVD and diabetes, in the Cohort of Swedish Men and the Swedish Mammography Cohort...
September 28, 2016: American Journal of Clinical Nutrition
Shalini Vaid, Lynae Hanks, Russell Griffin, Ambika P Ashraf
BACKGROUND: Patients with type 1 diabetes mellitus (T1DM) have an extremely high risk of cardiovascular disease (CVD) morbidity and mortality. It is well known that dyslipidemia is a subclinical manifestation of atherosclerosis. OBJECTIVE: To analyze presence and predicting factors of lipoprotein abnormalities prevalent in children with T1DM and whether race-specific differences exist between non-Hispanic white (NHW) and non-Hispanic black (NHB) in the lipoprotein characteristics...
September 2016: Journal of Clinical Lipidology
Kumpatla Satyavani, Sekar Archana, Ajay Mv Kumar, Shanta Achanta, Vijay Viswanathan
OBJECTIVE: To assess the sex differences in the prevalence of cardiovascular risk factors among patients with type 2 diabetes, visiting the hospital between March-December 2012. METHODS: A cross-sectional study was performed among the type 2 diabetes patients attending M.V. Hospital for Diabetes, a tertiary centre specialized in diabetes care, Chennai, South India. We collected information on obesity (body mass index ≥25 kg/m2), hypertension, dyslipidemia, smoking, alcohol consumption and glycemic control (HbA1c >8% considered poor control)...
December 2015: Journal of the Association of Physicians of India
Eun Young Lee, Hae Kyung Yang, Joonyub Lee, Borami Kang, Yeoree Yang, Seung-Hwan Lee, Seung-Hyun Ko, Yu-Bae Ahn, Bong Yun Cha, Kun-Ho Yoon, Jae Hyoung Cho
BACKGROUND: Insulin resistance is one of the most important contributing factors to cardiovascular disease. This study aimed to investigate the association between coronary artery stenosis (CAS) and triglyceride glucose index (TyG index), a simple insulin resistance marker, in asymptomatic subjects with type 2 diabetes. METHODS: We recruited asymptomatic adults with type 2 diabetes but without previous history of coronary heart disease (n = 888). Significant CAS was defined as maximum intraluminal stenosis ≥70 % by coronary CT angiography...
2016: Lipids in Health and Disease
Miho Kamakura, Ryoko Maruyama
A high glycemic status increases the risk for autonomic dysfunction and cardiovascular failure. The aim of this study was to investigate time-dependent changes in the autonomic response and cardiovascular dynamics and the association between the level of hemoglobin A1c (HbA1c) and autonomic response during blood volume reduction. The study population consisted of 26 preoperative participants who were scheduled for autologous blood donation (200-400 mL of whole blood) for intraoperative or postoperative use...
2016: Tohoku Journal of Experimental Medicine
Teresa Vanessa Fiorentino, Franz Sesti, Francesco Andreozzi, Elisabetta Pedace, Angela Sciacqua, Marta Letizia Hribal, Francesco Perticone, Giorgio Sesti
BACKGROUND AND AIMS: Evidence suggests that combining 1-hour plasma glucose ≥155 mg/dl during an oral glucose tolerance test (OGTT) with glycosylated hemoglobin (HbA1c) significantly increases their predictive power for incident diabetes, while their individual and joint associations with cardio-metabolic risk factors remain undefined. Herein, we evaluated whether 1-hour post-load plasma glucose ≥155 mg/dl combined with HbA1c may identify pre-diabetic individuals with a higher cardio-metabolic risk...
October 2016: Atherosclerosis
Dorota Różańska, Anna Kawicka, Klaudia Konikowska, Agnieszka Salomon, Katarzyna Zatońska, Andrzej Szuba, Bożena Regulska-Ilow
BACKGROUND: Glycemic Load (GL) is one of the indicators that can be used to assess the nutritional value of the diet. The results of numerous studies have shown that high glycemic index and/or high GL diets were associated with increased risk for type 2 diabetes, cardiovascular disease and cancer. OBJECTIVES: The aim of the study was to evaluate dietary GL, intake of food products which are source of carbohydrates and contribution of particular carbohydrates in students' diets...
2016: Roczniki Państwowego Zakładu Higieny
Nancy Helou, Andrew Dwyer, Maya Shaha, Anne Zanchi
BACKGROUND: The increasing prevalence of diabetes poses significant challenges to healthcare systems around the world. Diabetes is the leading cause of end-stage renal disease. Diabetic kidney disease (DKD) is becoming a global health concern because it is a progressive disease associated with major health complications and increased health costs. The treatment goals for DKD are to slow the progression of the renal disease and prevent cardiovascular events. Accordingly, patients are expected to adhere to prescribed treatments and manage a wide range of daily self-care activities...
July 2016: JBI Database of Systematic Reviews and Implementation Reports
I Zazpe, S Santiago, A Gea, M Ruiz-Canela, S Carlos, M Bes-Rastrollo, M A Martínez-González
BACKGROUND AND AIMS: Beyond the quantity of carbohydrate intake, further research is needed to know the relevance of carbohydrate quality following operational indices. No previous longitudinal study has assessed the association between an index for quality of dietary carbohydrate intake and the risk of cardiovascular disease (CVD). Here, we examined the association between a carbohydrate quality index (CQI) and the risk of CVD. METHODS AND RESULTS: We used a validated semi-quantitative 136-item food-frequency questionnaire (FFQ) in a prospective follow-up study of 17,424 middle-aged adults from Spain...
July 12, 2016: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
Mark Inman, Denis Daneman, Jacqueline Curtis, Etienne Sochett, Antoine Clarke, David B Dunger, John Deanfield, Farid H Mahmud
OBJECTIVE: To evaluate the relationship between social determinants of health (SDH) and cardiovascular disease (CVD) risk factors as well as a measure of arterial stiffness in adolescents with type 1 diabetes (T1D). STUDY DESIGN: SDH were measured with the validated Ontario Marginalization Index, derived from deidentified postal code data and stratified by quintile (first  = least deprived; fifth = most deprived). SDH dimensions included material deprivation; ethnic concentration; and measures of dependency and residential instability...
October 2016: Journal of Pediatrics
Rosamar E F Rezende, Sebastião M B Duarte, Jose T Stefano, Hamilton Roschel, Bruno Gualano, Ana L de Sá Pinto, Denise C P Vezozzo, Flair J Carrilho, Claudia P Oliveira
OBJECTIVE: The aim of the study was to evaluate the effectiveness of aerobic physical activity in reducing the frequency of hepatic steatosis and metabolic and cardiovascular risk in postmenopausal women with nonalcoholic fatty liver disease (NAFLD). METHODS: Forty sedentary postmenopausal women (mean age 55.3 ± 8.0 y) with biopsy-proven NAFLD were randomly divided into two groups: an exercising group (19 participants) and a control group (nonexercising, 21 participants)...
August 2016: Menopause: the Journal of the North American Menopause Society
Bruna Cherubini Alves, Thaís Rasia da Silva, Poli Mara Spritzer
Introduction Cardiovascular disease (CVD) is the leading cause of death in post menopausal women, and inflammation is involved in the atherosclerosis process. Purpose to assess whether dietary pattern, metabolic profile, body composition and physical activity are associated with low-grade chronic inflammation according to high-sensitivity C-reactive protein (hs-CRP) levels in postmenopausal women. Methods ninety-five postmenopausal participants, with no evidence of clinical disease, underwent anthropometric, metabolic and hormonal assessments...
July 2016: Revista Brasileira de Ginecologia e Obstetrícia
Daniel Borch, Nicole Juul-Hindsgaul, Mette Veller, Arne Astrup, Jörn Jaskolowski, Anne Raben
BACKGROUND: Potatoes have been related to increased risks of obesity, type 2 diabetes (T2D), and cardiovascular disease (CVD) mainly because of their high glycemic index. OBJECTIVE: We conducted a systematic review to evaluate the relation between intake of potatoes and risks of obesity, T2D, and CVD in apparently healthy adults. DESIGN: MEDLINE, Embase, the Web of Science, and the Cochrane Central Register of Controlled Trials were searched for intervention and prospective observational studies that investigated adults without any known illnesses at baseline, recorded intake of potatoes, and measured adiposity (body weight, body mass index, or waist circumference), cases of T2D, cases of cardiovascular events, or risk markers thereof...
August 2016: American Journal of Clinical Nutrition
Ahmad Haider, Aksam Yassin, Karim Sultan Haider, Gheorghe Doros, Farid Saad, Giuseppe Mc Rosano
BACKGROUND/OBJECTIVES: Long-term testosterone therapy (TTh) in men with hypogonadism has been shown to improve all components of the metabolic syndrome. In this study, we investigated the effects of long-term TTh up to 8 years in hypogonadal men with a history of cardiovascular disease (CVD). PATIENTS AND METHODS: In two urological clinics observational registries, we identified 77 hypogonadal men receiving TTh who also had a history of CVD. The effects of TTh on anthropometric and metabolic parameters were investigated for a maximum duration of 8 years...
2016: Vascular Health and Risk Management
Marilia Brito Gomes, Carlos Antonio Negrato, Ana Almeida, Antonio Ponce de Leon
AIM: To determine the relationship between parity, glycemic control, cardiovascular risk factors and diabetes-related chronic complications in women with type 1 diabetes. METHODS: This was a multicenter cross-sectional study conducted between December 2008 and December 2010 in 28 public clinics in 20 cities from the 4 Brazilian geographic regions. Data were obtained from 1532 female patients, 59.2% Caucasians, and aged 25.2 ± 10.6 years. Diabetes duration was of 11...
June 25, 2016: World Journal of Diabetes
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