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https://www.readbyqxmd.com/read/29673847/challenges-in-the-management-of-type-2-diabetes-among-native-women-in-the-united-arab-emirates
#1
Walaa Abuelmagd, Bachar Afandi, Helle Håkonsen, Seham Khmidi, Else-Lydia Toverud
AIM: To investigate type 2 diabetes mellitus (T2DM) management in native female patients in the United Arab Emirates (UAE). METHODS: Ninety women from the outpatient diabetes clinic at Tawam Hospital, UAE, were interviewed face-to-face using a structured questionnaire. Glycated hemoglobin (HbA1c), blood pressure, lipid panel, weight and body mass index (BMI) were extracted from medical records. RESULTS: Mean age was 57.5 (SD:12.7) years. Forty-five participants (50...
April 16, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29672274/cutaneous-mucormycosis-as-a-presenting-feature-of-type-1-diabetes-in-a-boy-case-report-and-review-of-the-literature
#2
Ganesh Jevalikar, Siddhnath Sudhanshu, Sanjay Mahendru, Smita Sarma, Khalid J Farooqui, Ambrish Mithal
BACKGROUND: Mucormycosis is a potentially fatal complication of diabetes. The rhino-orbito-cerebral form is the most common presentation, however, rarely other types can also be seen. CASE PRESENTATION: We describe the case of a 4½ -year-old boy not previously known to be a diabetic who presented to the plastic surgery department for gangrene of the left middle finger with surrounding erythema and induration. After the diagnosis of diabetes and initial treatment, pus from the wound showed broad aseptate hyphae suggestive of mucormycosis which was further confirmed on culture...
April 19, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29670330/the-efficacy-and-safety-of-ginkgo-biloba-extract-as-an-adjuvant-in-type-2-diabetes-mellitus-patients-ineffectively-managed-with-metformin-a-double-blind-randomized-placebo-controlled-trial
#3
Tavga Ahmed Aziz, Saad Abdulrahman Hussain, Taha Othman Mahwi, Zheen Aorahman Ahmed, Heshu Sulaiman Rahman, Abdullah Rasedee
Background and aim: Type 2 diabetes mellitus (T2DM) is one of the major diseases confronting the health care systems. In diabetes mellitus (DM), combined use of oral hypoglycemic medications has been shown to be more effective than metformin (Met) alone in glycemic control. This study determined the effects of Ginkgo biloba (GKB) extract as an adjuvant to Met in patients with uncontrolled T2DM. Subjects and methods: Sixty T2DM patients were recruited in a randomized, placebo-controlled, double-blinded, and multicenter trial...
2018: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29668601/efficacy-and-safety-of-once-weekly-semaglutide-for-the-treatment-of-type-2-diabetes-protocol-for-a-systematic-review-and-meta-analysis
#4
Fang-Hong Shi, Hao Li, Min Cui, Zai-Li Zhang, Zhi-Chun Gu, Xiao-Yan Liu
BACKGROUND: It is a great challenge for type 2 diabetes mellitus (T2DM) patients to maintain optimal glycemia, control body weight, blood pressure, and avoiding hypoglycemia. Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1 RAs) can stimulate glucose-dependent insulin while inhibit glucagon secretion, delay gastric emptying, reduce appetite, and energy intake. Recently, a new once-weekly GLP-1 RAs, semaglutide, has been registered to treat patients with T2DM. METHODS: We will search Medline, Embase, Cochrane Library, and the ClinicalTrials...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29668313/dietary-glycemic-load-glycemic-index-and-carbohydrate-intake-on-the-risk-of-lung-cancer-among-men-and-women-in-shanghai
#5
Jiang-Wei Sun, Wei Zheng, Hong-Lan Li, Jing Gao, Gong Yang, Yu-Tang Gao, Nat Rothman, Qing Lan, Xiao-Ou Shu, Yong-Bing Xiang
To investigate the potential influence of dietary glycemic index, glycemic load, or carbohydrate intake and lung cancer risk in Shanghai. We prospectively investigated the associations among 130,858 participants in the Shanghai Women's and Men's Health Studies. Diet was assessed using validated food-frequency questionnaires. Lung cancer cases were ascertained through annual record linkage and every 2-3 years in-home visits. Cox proportional hazard regression model was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs)...
April 18, 2018: Nutrition and Cancer
https://www.readbyqxmd.com/read/29666544/efficiency-of-selected-food-ingredients-on-protein-efficiency-ratio-glycemic-index-and-in-vitro-digestive-properties
#6
M B Anusha, Naveen Shivanna, G Phani Kumar, K R Anilakumar
The human body on exposure to high-altitude, undergoes many physiological challenges. The cardiopulmonary reserves are favoured against the digestive system. Hence, the efficiency of digestion is compromised to a great extent, which leads to anorexia, hypophagia, epigastralgia, dyspepsia, nausea, and peptic ulcers. The present study was focused on in vitro digestive influence of selected food ingredients viz. cardamom, carom, cumin, coriander, fennel, fenugreek, ginger, pepper, star anise, turmeric, papaya, orange, pineapple, liquorice, valerian, and tarragon on the activities of digestive enzymes of rat pancreas, duodenum, and small intestine...
May 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29666515/effect-of-fiber-sources-on-fatty-acids-profile-glycemic-index-and-phenolic-compound-content-of-in-vitro-digested-fortified-wheat-bread
#7
Marcin Andrzej Kurek, Jarosław Wyrwisz, Sabina Karp, Agnieszka Wierzbicka
In this study, some dietary fiber (DF) sources were investigated as fortifiers of wheat bread: oat (OB), flax (FB), and apple (AB). Adding oat and flax fibers to bread significantly changed the fatty acid profiles. OB was highest in oleic acid (33.83% of lipids) and linoleic acid (24.31% of lipids). Only in FB, γ-linolenic fatty acid was present in a significant amount-18.32%. The bioaccessibility trails revealed that the DF slow down the intake of saturated fatty acids. PUFA were least bioaccessible from all fatty acids groups in the range of (72% in OB to 87% in FB)...
May 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29660612/perfluoroalkyl-substances-and-glycemic-status-in-pregnant-danish-women-the-odense-child-cohort
#8
Richard Christian Jensen, Dorte Glintborg, Clara Amalie Gade Timmermann, Flemming Nielsen, Henriette Boye Kyhl, Helle Raun Andersen, Philippe Grandjean, Tina Kold Jensen, Marianne Andersen
BACKGROUND: Perfluoroalkyl substances (PFASs) are persistent chemicals with suspected endocrine disrupting abilities applied in consumer products. PFASs have potentially modulating effects on glucose homeostasis. Insulin resistance prevails during third trimester of pregnancy, and this challenge of glucose homeostasis may reveal putative effects of PFAS concentrations on glycemic status. OBJECTIVE: To investigate associations between five serum PFASs and glucose-related outcomes in pregnant Danish women based on their risk of gestational diabetes mellitus (GDM)...
April 13, 2018: Environment International
https://www.readbyqxmd.com/read/29659967/carbohydrate-replacement-of-rice-or-potato-with-lentils-reduces-the-postprandial-glycemic-response-in-healthy-adults-in-an-acute-randomized-crossover-trial
#9
Dita Moravek, Alison M Duncan, Laura B VanderSluis, Sarah J Turkstra, Erica J Rogers, Jessica M Wilson, Aileen Hawke, D Dan Ramdath
Background: The postprandial blood glucose response (PBGR) following carbohydrate replacement of high-glycemic index (GI) foods with pulses, in a mixed meal, has not been accurately defined. Objective: We aimed to determine the extent to which PBGR and relative glycemic response (RGR) are lowered when half of the available carbohydrate (AC) from rice or potato is replaced with cooked lentils. Methods: Using a crossover design, 2 groups of 24 healthy adults randomly consumed 50 g AC from control white rice alone [mean ± SD body mass index (BMI, in kg/m2): 24...
April 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29655711/characterizations-of-the-endogenous-starch-hydrolase-inhibitors-in-acorns-of-quercus-fabri-hance
#10
Yi Lin, Yuyun Lu, Zhixuan Song, Dejian Huang
The acorns of Quercus fabri Hance tree, or the mandarin duck fruits have been consumed by locals in the form of noodle, yet there is little scientific study. We found that they have much lower digestibility compared with that of rice flour. Solvent extraction using hexane, dichloromethane, and acetone-ethanol-water (AEW) mixture yielded three fractions but the starch hydrolase inhibitors were only found in the AEW fraction. Using assay-guided fractionation of the extracts, we were able to further separate the active compounds by using Sephadex LH-20 column and characterize the inhibitor chemical identities by LC-MS( n ) ...
August 30, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29651629/high-normal-serum-thyrotropin-levels-and-increased-glycemic-variability-in-type-2-diabetic-patients
#11
Jian-Bin Su, Li-Hua Zhao, Xiu-Lin Zhang, Hong-Li Cai, Hai-Yan Huang, Feng Xu, Tong Chen, Xue-Qin Wang
PURPOSE: High-normal thyrotropin (TSH) is related to reduced insulin sensitivity and may contribute to glycemic disorders in diabetes. We investigated the relationship between normal serum TSH levels and glycemic variability in euthyroid type 2 diabetic patients. METHODS: A total of 432 newly diagnosed type 2 diabetic patients with euthyroid function and normal serum TSH levels were recruited between March 2013 and February 2017. Insulin sensitivity was evaluated by the Matsuda index (ISIMatsuda ) following a 75-g oral glucose tolerance test...
April 12, 2018: Endocrine
https://www.readbyqxmd.com/read/29650309/open-loop-glucose-control-automatic-iob-based-super-bolus-feature-for-commercial-insulin-pumps
#12
Nicolás Rosales, Hernán De Battista, Josep Vehí, Fabricio Garelli
BACKGROUND AND OBJECTIVE: Although there has been significant progress towards closed-loop type 1 diabetes mellitus (T1DM) treatments, most diabetic patients still treat this metabolic disorder in an open-loop manner, based on insulin pump therapy (basal and bolus insulin infusion). This paper presents a method for automatic insulin bolus shaping based on insulin-on-board (IOB) as an alternative to conventional bolus dosing. METHODS: The methodology presented allows the pump to generate the so-called super-bolus (SB) employing a two-compartment IOB dynamic model...
June 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29629915/endothelial-dysfunction-is-related-to-glycemic-variability-and-quality-and-duration-of-sleep-in-adults-with-type-1-diabetes
#13
Sarah S Farabi, Laurie Quinn, Shane Phillips, Dan Mihailescu, Chang Park, Mohammed Ali, Pamela Martyn-Nemeth
BACKGROUND: Elevated cardiovascular disease risk in people with type 1 diabetes (T1DM) is incompletely understood. Glycemic control, glycemic variability, and sleep quality and duration may relate to cardiovascular disease risk in this population via endothelial dysfunction. OBJECTIVE: The aim of this study was to examine relationships among glycemic control, glycemic variability, sleep quality and duration, and endothelial function in adults with T1DM. METHODS: Endothelial function was measured using flow-mediated dilation...
April 7, 2018: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29629525/high-dietary-glycemic-load-is-associated-with-poor-functional-outcome-in-patients-with-acute-cerebral-infarction
#14
Tae Jin Song, Yoonkyung Chang, Min Young Chun, Chan Young Lee, A Ram Kim, Yuri Kim, Yong Jae Kim
BACKGROUND AND PURPOSE: Elevated postprandial blood glucose is a critical risk factor for stroke. The dietary glycemic load (GL) and glycemic index (GI) are frequently used as markers of the postprandial blood glucose response to estimate the overall glycemic effect of diets. We hypothesized that high dietary GL, GI, or total carbohydrate intake is associated with a poor functional outcome in patients with acute ischemic stroke. METHODS: We prospectively included 263 first-ever ischemic stroke patients who completed a semiquantitative food-frequency questionnaire...
April 2018: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/29624850/association-of-advanced-glycation-end-products-with-peri-implant-inflammation-in-prediabetes-and-type-2-diabetes-mellitus-patients
#15
Mohammed Alrabiah, Khulud Abdulrahman Al-Aali, Zeyad H Al-Sowygh, Abdulelah M Binmahfooz, Sameer A Mokeem, Tariq Abduljabbar
BACKGROUND: It is postulated that peri-implant sulcular fluid (PISF) levels of advanced glycation end products (AGEs) are higher with high glycemic levels. PURPOSE: In the present clinico-biochemical study, we explored the clinical and radiographic peri-implant parameters and levels of AGEs among prediabetic, type 2 diabetic (T2DM), and non-diabetic patients and to evaluate the correlation of AGEs with clinical peri-implant parameters. MATERIALS AND METHODS: Ninety patients were divided into three groups of 30 patients each; group 1: patients with prediabetes; group 2: patients with T2DM; and group 3: non-diabetic individuals...
April 6, 2018: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29621322/sexual-dimorphism-in-the-association-between-gestational-diabetes-mellitus-and-overweight-in-offspring-at-5-7-years-the-obegest-cohort-study
#16
Nathalie Le Moullec, Adrian Fianu, Olivier Maillard, Emilie Chazelle, Nadège Naty, Chantal Schneebeli, Patrick Gérardin, Laetitia Huiart, Marie-Aline Charles, François Favier
Evidence from literature is mixed regarding a possible association of maternal gestational diabetes mellitus (GDM) and overweight in the offspring. Sexual dimorphism, or sex disparities in the pathogenesis linking GDM exposure to overweight, could be at play. The objective of this study was to investigate the association between GDM and child overweight at 5-7 years. Six hundred pairs (1:1) of Reunionese liveborn singletons selected from a hospital-based birth registry, matched for sex, gestational age, and birth period, underwent a prospective in-home follow-up and were analyzed with respect to their exposure to GDM...
2018: PloS One
https://www.readbyqxmd.com/read/29618311/predicting-factors-affecting-glucose-monitoring-treatment-satisfaction-and-drug-attitude-inventory-adherence-among-patients-with-type-2-diabetes-mellitus-cross-sectional-observational-study
#17
Syed Ata Ur Rahman
OBJECTIVES: The study aimed to explore the predictors affecting patient satisfaction to glucose monitoring system (GMSS) and drug attitude inventory (DAI) / treatment adherence among type 2 diabetes mellitus patients. METHODS: Cross-sectional observational study design was used to conduct this study. Subjective assessments were made by questionnaires and objective data was collected from the patients' medication profiles registered to diabetic clinics. Patients were recruited from five different public hospitals of Hyderabad region, India...
April 4, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29617350/co-ingestion-of-rice-bran-soymilk-or-plain-soymilk-with-white-bread-effects-on-the-glycemic-and-insulinemic-response
#18
Stefan Gerardus Camps, Joseph Lim, Atsushi Ishikado, Yumi Inaba, Makoto Suwa, Motonobu Matsumoto, Christiani Jeyakumar Henry
The regular consumption of soy products is associated with inverse incidence of type 2 diabetes, and there has been an increasing interest in the glycemia reducing potential of rice bran and its components. In this study, we investigated whether consuming soymilk with the addition of rice bran (fiber) can reduce the glycemic response of a carbohydrate meal. Seventeen healthy Asian men (BMI: 18.5-29 kg/m²) participated in this randomized crossover trial. On four occasions, they consumed white bread (two times) and white bread with two different soymilks differing in protein and rice bran content...
April 4, 2018: Nutrients
https://www.readbyqxmd.com/read/29610581/bridging-glycated-hemoglobin-with-quality-of-life-and-health-state-a-randomized-case-control-study-among-type-2-diabetes-patients
#19
Syed Wasif Gillani, Irfan Altaf Ansari, Hisham A Zaghloul, Mohi Iqbal Mohammad Abdul, Syed Azhar Syed Sulaiman, Mirza R Baig
Background: The aim of this study was to explore the predictors of QOL and health state and examine the relationship with glycemic control among type 2 diabetes mellitus (T2DM) patients. Methods: A randomized cross-sectional case-control study was conducted among n = 600 T2DM patients of Malaysia. Study population was distributed into three groups as: controls: patients with HbA1c ≤ 7 (n = 199), cases arm 1: with HbA1c 7-7.9 (n = 204) and cases arm 2 (n = 197): with HbA1c ≥ 8 consecutively last 3 times...
2018: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29609470/relationships-between-glycemic-control-and-cardiovascular-fitness
#20
Elizabeth W Moxley, Donald Smith, Lauretta Quinn, Chang Gi Park
INTRODUCTION: Diabetes is a serious health problem affecting approximately 29.1 million individuals in the United States. Another 86 million have prediabetes. The development and implementation of lifestyle modifications such as physical activity for these persons are among the most effective methods for prevention and treatment. OBJECTIVE: The aim of this study was to examine relationships between glycemic control (HbA1c) and cardiovascular fitness (peak maximal oxygen uptake [VO2 peak] and ventilatory threshold [VT]) in overweight/obese subjects with and without type 2 diabetes (T2DM)...
January 1, 2018: Biological Research for Nursing
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