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https://www.readbyqxmd.com/read/29161335/shoulder-complaints-in-wheelchair-athletes-a-systematic-review
#1
Omar W Heyward, Riemer J K Vegter, Sonja de Groot, Lucas H V van der Woude
BACKGROUND: In recent years the popularity of disabled sports and competition among disabled athletes has grown considerably. With this rise in exposure of, and participation in wheelchair sports comes an increase in related stressors, including musculoskeletal load. External mechanical loading may increase the risk of shoulder complaints. The objective of this literature review was to 1) identify and describe the prevalence and/or incidence of shoulder complaints in wheelchair athletes in the literature, to 2) examine the factors and underlying mechanisms that could be potentially involved, and 3) provide some insights into the development of preventative measures...
2017: PloS One
https://www.readbyqxmd.com/read/29158412/induced-gnas-r201h-expression-from-the-endogenous-gnas-locus-causes-fibrous-dysplasia-by-up-regulating-wnt-%C3%AE-catenin-signaling
#2
Sanjoy Kumar Khan, Prem Swaroop Yadav, Gene Elliott, Dorothy Zhang Hu, Ruoshi Xu, Yingzi Yang
Fibrous dysplasia (FD; Online Mendelian Inheritance in Man no. 174800) is a crippling skeletal disease caused by activating mutations of the GNAS gene, which encodes the stimulatory G protein Gαs FD can lead to severe adverse conditions such as bone deformity, fracture, and severe pain, leading to functional impairment and wheelchair confinement. So far there is no cure, as the underlying molecular and cellular mechanisms remain largely unknown and the lack of appropriate animal models has severely hampered FD research...
November 20, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29157032/pain-fatigue-function-and-participation-among-long-term-manual-wheelchair-users-partnered-with-a-mobility-service-dog
#3
Claude Vincent, Dany H Gagnon, Frédéric Dumont
PURPOSE: To assess the effects of a mobility service dog (MSD) on pain, fatigue, wheelchair-related functional tasks, participation and satisfaction among manual wheelchair users over a nine-month period. METHOD: A longitudinal study with repeated assessment times before and three, six and nine months after intervention was achieved. Intervention consisted in partnering each participant with a MSD. The setting is a well-established provincial service dog training school and participants homes...
November 20, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29154419/clinical-profiles-and-prognosis-of-acute-heart-failure-in-adult-patients-with-dystrophinopathies-on-home-mechanical-ventilation
#4
Abdallah Fayssoil, Rabah Ben Yaou, Adam Ogna, France Leturcq, Olivier Nardi, Bernard Clair, Karim Wahbi, Frederic Lofaso, Pascal Laforet, Denis Duboc, David Orlikowski, Djillali Annane
AIMS: Duchenne muscular dystrophy (DMD) is characterized by respiratory and heart involvements. In the context of permanently wheelchair bound and on mechanical ventilation (MV) patients, the clinical presentation of acute heart failure (AHF) syndrome may be atypical. We sought to describe clinical and genetic profiles and to determine prognosis of DMD and Becker muscular dystrophy (BMD) patients on home MV (HMV), hospitalized for AHF. METHODS AND RESULTS: We included genetically proven DMD and BMD patients on HMV admitted for AHF...
November 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/29140616/comparisons-of-agricultural-seating-for-paraplegia
#5
Carla Sue Wilhite, William E Field, Mark Jaramillo, Kevin Sullivan
People with spinal cord injury/paraplegia are operating agricultural machinery despite the lack of research evidence to support seating interventions. These operators represent a vulnerable population in the agricultural workforce, and information to support their health in the workplace is urgently warranted. This research compared a group of subjects with paraplegia on different intervention cushion conditions during a simulated tractor driving task. Numerical data acquired from a pressure-mapping instrument were explored for statistical relationships within a small cohort of people with paraplegia participating in a feasibility study that was previously reported for clinical results...
January 26, 2017: Journal of Agricultural Safety and Health
https://www.readbyqxmd.com/read/29140190/evaluation-of-a-shoulder-injury-prevention-program-in-wheelchair-basketball
#6
Jereme Wilroy, Elizabeth Hibberd
CONTEXT: Previous literature has theorized that alterations in shoulder physical characteristics are present in wheelchair athletes and contribute to shoulder pain and injury. Limited empirical evidence is present that evaluates the effectiveness of a shoulder injury prevention program focusing on improving these altered characteristics. OBJECTIVE: To evaluate the effectiveness of a 6-week intervention program at improving characteristics that increases the risk of developing pain or shoulder injury...
November 15, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/29134178/wheelchair-services-and-use-outcomes-a-cross-sectional-survey-in-kenya-and-the-philippines
#7
Eva S Bazant, Elizabeth J Himelfarb Hurwitz, Brenda N Onguti, Emma K Williams, Jamie H Noon, Cheryl A Xavier, Ferdiliza D S Garcia, Anthony Gichangi, Mohammed Gabbow, Peter Musakhi, R Lee Kirby
Background: The World Health Organisation recommends that services accompany wheelchair distribution. This study examined the relationship of wheelchair service provision in Kenya and the Philippines and wheelchair-use-related outcomes. Method: We surveyed 852 adult basic manual wheelchair users. Participants who had received services and those who had not were sought in equal numbers from wheelchair-distribution entities. Outcomes assessed were daily wheelchair use, falls, unassisted outdoor use and performance of activities of daily living (ADL)...
2017: Afr J Disabil
https://www.readbyqxmd.com/read/29133201/diabetes-related-amputations-create-considerable-public-health-burden-in-the-uk
#8
REVIEW
Heather Graz, Vijay K D Souza, David E C Alderson, Michael Graz
AIMS: The main aim of this study was to assess the cost of diabetic amputation (both direct and indirect) to the National Health Service from the point of amputation onwards. METHODS: This systematic review involved searches of published literature between January 2007 and March 2017 mainly using the bibliographic databases, the Cochrane Library, EMBASE via Ovid(®), MEDLINE via Ovid(®), as well as grey literature, both in print and in electronic formats published through non-commercial publications, which reported the cost of amputation due to diabetic foot ulcers RESULTS: The studies included in this review varied considerably in estimating the cost including cost elements and how those costs were categorised...
November 10, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29132727/speed-profiles-in-wheelchair-court-sports-comparison-of-two-methods-for-measuring-wheelchair-mobility-performance
#9
R M A van der Slikke, B S Mason, M A M Berger, V L Goosey-Tolfrey
Wheelchair mobility performance is an important aspect in most wheelchair court sports, commonly measured with an indoor tracking system or wheelchair bound inertial sensors. Both methods provide key wheelchair mobility performance outcomes regarding speed. In this study, we compared speed profiles of both methods to gain insight into the level of agreement, for recommendations regarding future performance measurement. Data were obtained from 5 male highly trained wheelchair basketball players during match play...
November 10, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29132427/risk-of-falling-among-hospitalized-patients-with-high-modified-morse-scores-could-be-further-stratified
#10
Irina Gringauz, Yael Shemesh, Amir Dagan, Irina Israelov, Dana Feldman, Naama Pelz-Sinvani, Dan Justo, Gad Segal
BACKGROUND: Falls during hospitalization harbor both clinical and financial outcomes. The modified Morse fall scale [MMFS] is widely used for an in-hospital risk-of-fall assessment. Nevertheless, the majority of patients at risk of falling, i.e. with high MMFS, do not fall. The aim of this study was to ascertain our study hypothesis that certain patients' characteristics (e.g. serum electrolytes, usage of a walking device etc.) could further stratify the risk of falls among hospitalized patients with MMFS...
November 13, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29130752/self-reported-difficulty-and-preferences-of-wheeled-mobility-device-users-for-simulated-low-floor-bus-boarding-interior-circulation-and-disembarking
#11
Clive D'Souza, Victor L Paquet, James A Lenker, Edward Steinfeld
BACKGROUND: Low ridership of public transit buses among wheeled mobility device users suggests the need to identify vehicle design conditions that are either particularly accommodating or challenging. The objective of this study was to determine the effects of low-floor bus interior seating configuration and passenger load on wheeled mobility device user-reported difficulty, overall acceptability and design preference. METHODS: Forty-eight wheeled mobility users evaluated three interior design layouts at two levels of passenger load (high vs...
November 13, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29126212/hereditary-spastic-paraplegia-type-5-natural-history-biomarkers-and-a-randomized-controlled-trial
#12
Ludger Schöls, Tim W Rattay, Peter Martus, Christoph Meisner, Jonathan Baets, Imma Fischer, Christine Jägle, Matthew J Fraidakis, Andrea Martinuzzi, Jonas Alex Saute, Marina Scarlato, Antonella Antenora, Claudia Stendel, Philip Höflinger, Charles Marques Lourenco, Lisa Abreu, Katrien Smets, Martin Paucar, Tine Deconinck, Dana M Bis, Sarah Wiethoff, Peter Bauer, Alessia Arnoldi, Wilson Marques, Laura Bannach Jardim, Stefan Hauser, Chiara Criscuolo, Alessandro Filla, Stephan Züchner, Maria Teresa Bassi, Thomas Klopstock, Peter De Jonghe, Ingemar Björkhem, Rebecca Schüle
Spastic paraplegia type 5 (SPG5) is a rare subtype of hereditary spastic paraplegia, a highly heterogeneous group of neurodegenerative disorders defined by progressive neurodegeneration of the corticospinal tract motor neurons. SPG5 is caused by recessive mutations in the gene CYP7B1 encoding oxysterol-7α-hydroxylase. This enzyme is involved in the degradation of cholesterol into primary bile acids. CYP7B1 deficiency has been shown to lead to accumulation of neurotoxic oxysterols. In this multicentre study, we have performed detailed clinical and biochemical analysis in 34 genetically confirmed SPG5 cases from 28 families, studied dose-dependent neurotoxicity of oxysterols in human cortical neurons and performed a randomized placebo-controlled double blind interventional trial targeting oxysterol accumulation in serum of SPG5 patients...
November 6, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29125503/patient-preferences-for-treatments-of%C3%A2-neuromuscular-diseases-a-systematic-literature-review
#13
Erik Landfeldt, Josefin Edström, Peter Lindgren, Hanns Lochmüller
BACKGROUND: Treatment decisions of neuromuscular diseases involve weighing clinical benefits and risks, as well as impact on patient social life, work status, other activities of daily living, and health-related quality of life. OBJECTIVE: To conduct a systemic literature review of patient preferences for treatments of neuromuscular diseases. METHODS: We searched Embase, Web of Science, and PubMed for full-text articles reporting results from studies of patient preferences for treatments of neuromuscular diseases...
November 8, 2017: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/29124014/a-molecular-analysis-of-the-gaa-gene-and-clinical-spectrum-in-38-patients-with-pompe-disease-in-japan
#14
Yasuyuki Fukuhara, Naoko Fuji, Narutoshi Yamazaki, Asami Hirakiyama, Tetsuharu Kamioka, Joo-Hyun Seo, Ryuichi Mashima, Motomichi Kosuga, Torayuki Okuyama
Pompe disease is an autosomal recessive disorder caused by acid α-glucosidase (GAA) deficiency, which results in the accumulation of glycogen in lysosomes in multiple tissues, including cardiac, skeletal, and smooth muscle cells. Thus far, 558 sequence variants of the GAA gene have been published in the Pompe Disease Mutation Database, and some mutations appear with considerable frequency in particular ethnic groups, such as Caucasians, Taiwanese, Chinese, and Koreans. However, the GAA mutation pattern in Japanese patients remains poorly understood...
March 2018: Molecular Genetics and Metabolism Reports
https://www.readbyqxmd.com/read/29123500/efficacy-and-the-safety-of-granulocyte-colony-stimulating-factor-treatment-in-patients-with-muscular-dystrophy-a-non-randomized-clinical-trial
#15
Dorota Sienkiewicz, Wojciech Kułak, Bożena Okurowska-Zawada, Grażyna Paszko-Patej, Janusz Wojtkowski, Karolina Sochoń, Anna Kalinowska, Kamila Okulczyk, Jerzy Sienkiewicz, Edward McEachern
Introduction: The current standard treatment for patients with Duchenne muscular dystrophy (DMD) involves corticosteroids. Granulocyte colony-stimulating factor (G-CSF) induces the proliferation of satellite cells and myoblasts and, in turn, muscle regeneration. Beneficial effects of G-CSF were also described for skeletal muscle disorders. Aim: We assessed the safety and effects of using G-CSF to promote muscle strength in patients with DMD. Materials and methods: Inclusion criteria were as follows: patients aged 5-15 years with diagnosed with DMD confirmed by genetic test or biopsy...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29122204/insights-on-the-apparel-needs-and-limitations-for-athletes-with-disabilities-the-design-of-wheelchair-rugby-sports-wear
#16
Sara Bragança, Ignacio Castellucci, Simeon Gill, Pascal Matthias, Miguel Carvalho, Pedro Arezes
Wheelchair rugby is a sport that has been gaining popularity with athletes with disabilities. However, as it is relatively new and not played by the masses, market specific sports-wear is not available for this sport, which impacts directly on performance and clothing satisfaction of the athletes. Therefore, the main objective of this research was to identify the problems that wheelchair rugby players face with the sports-wear they use for playing the game. The data was collected using a focus group and a questionnaire with 61 wheelchair rugby players in the United Kingdom...
February 2018: Applied Ergonomics
https://www.readbyqxmd.com/read/29111467/reverse-shoulder-arthroplasty-in-weight-bearing-shoulders-of-wheelchair-dependent-patients
#17
Eduard Alentorn-Geli, Nathan R Wanderman, Andrew T Assenmacher, Joaquín Sánchez-Sotelo, Robert H Cofield, John W Sperling
BACKGROUND: Wheelchair-dependent patients rely on their upper extremities for mobility and transfers. This entails the heavy use of upper extremities as weight-bearing joints, leading to shoulder overuse with increased prevalence of rotator cuff-related disorders, and ultimately to challenging cases for shoulder surgeons when a joint replacement is needed. OBJECTIVE: To report the outcomes of reverse shoulder arthroplasty (RSA) in wheelchair-dependent patients with arthritis and rotator cuff tears...
October 27, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29110736/wireless-intraoral-tongue-control-of-an-assistive-robotic-arm-for-individuals-with-tetraplegia
#18
Lotte N S Andreasen Struijk, Line Lindhardt Egsgaard, Romulus Lontis, Michael Gaihede, Bo Bentsen
BACKGROUND: For an individual with tetraplegia assistive robotic arms provide a potentially invaluable opportunity for rehabilitation. However, there is a lack of available control methods to allow these individuals to fully control the assistive arms. METHODS: Here we show that it is possible for an individual with tetraplegia to use the tongue to fully control all 14 movements of an assistive robotic arm in a three dimensional space using a wireless intraoral control system, thus allowing for numerous activities of daily living...
November 6, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29102079/early-onset-facioscapulohumeral-dystrophy-a-systematic-review-using-individual-patient-data
#19
REVIEW
Rianne J M Goselink, Nicol C Voermans, Kees Okkersen, Oebele F Brouwer, George W Padberg, Ana Nikolic, Rossella Tupler, Malgorzata Dorobek, Jean K Mah, Baziel G M van Engelen, Tim H A Schreuder, Corrie E Erasmus
Infantile or early onset is estimated to occur in around 10% of all facioscapulohumeral dystrophy (FSHD) patients. Although small series of early onset FSHD patients have been reported, comprehensive data on the clinical phenotype is missing. We performed a systematic literature search on the clinical features of early onset FSHD comprising a total of 43 articles with individual data on 227 patients. Additional data from four cohorts was provided by the authors. Mean age at reporting was 18.8 years, and 40% of patients were wheelchair-dependent at that age...
September 21, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/29099652/impact-of-short-compared-to-long-haul-international-travel-on-the-sleep-and-wellbeing-of-national-wheelchair-basketball-athletes
#20
Heidi R Thornton, Joanna Miller, Lee Taylor, Charli Sargent, Michele Lastella, Peter M Fowler
Currently, very little is known about the impact of short- or long-haul air travel on the sleep and wellbeing of wheelchair basketball athletes. Eleven national wheelchair basketball athletes wore actigraphy monitors prior, during, and after air travel to the United Kingdom. Upon arrival, participants rated their subjective jet-lag, fatigue, and vigor. Individuals traveled to the United Kingdom from different locations in Australia, the United States, and Europe and were categorised according to travel length [LONG (up to 30...
November 3, 2017: Journal of Sports Sciences
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