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Lactose intolerance

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https://www.readbyqxmd.com/read/29708972/analysis-of-lct-13910-genotypes-and-bone-mineral-density-in-ancient-skeletal-materials
#1
Barbara Mnich, Anna Elżbieta Spinek, Maciej Chyleński, Aleksandra Sommerfeld, Miroslawa Dabert, Anna Juras, Krzysztof Szostek
The relation of LCT-13910 genotypes and bone mineral density (BMD) has been the subject of modern-day human population studies, giving inconsistent results. In the present study we analyze for the first time a relation of LCT-13910 genotypes and BMD in historical skeletal individuals. Ancient population might be a model for testing this association due to elimination of non-natural factors affecting bone density. Among 22 medieval individuals from Sanok churchyard (South-Eastern Poland; dated from XIV to XVII c...
2018: PloS One
https://www.readbyqxmd.com/read/29686701/nontyphoidal-salmonella-gastroenteritis-in-a-tertiary-children-s-hospital-in-southern-china-characteristics-and-dietary-considerations
#2
Lu Ren, Min Yang, Lanlan Geng, Peiyu Chen, Huan Chen, Sitang Gong, Ding-You Li
Background: Nontyphoidal Salmonella infection is a common cause for acute bacterial gastroenteritis in children in China. There have been no reports of the prevalence of lactose intolerance or food allergies in children with nontyphoidal Salmonella infection. The aim of this study was to characterize nontyphoidal Salmonella gastroenteritis in a tertiary children's hospital and evaluate clinical presentation, lactose intolerance, and food allergies in children with prolonged nontyphoidal Salmonella gastroenteritis...
2018: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29649531/preparation-characterization-and-in-vitro-release-of-%C3%AE-galactosidase-loaded-polyelectrolyte-nanoparticles
#3
Hongcai Zhang, Huaning Yu, Jun Mei, Yifeng Zhang, Zilong Deng
Improving encapsulation efficacy (EE) and bioavailability of β-galactosidase (β-gal) is always a challenge due to its fragility. In this work, β-gal loaded β-chitosan (CS) nanoparticles (NPs) were successfully prepared based on ionic gelation technique and electrostatic attraction for improving its EE and in vitro releasing capacity. The particle size of β-gal loaded low and high molecular weight (LMW and HMW) β-CS NPs reached 584.37 and 652.46 nm, with Zeta-potential (ZP) of 26.37 and 16.46 mV under the optimal conditions, respectively...
April 9, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29608017/improvement-of-functional-properties-of-a-thermostable-%C3%AE-glycosidase-for-milk-lactose-hydrolysis
#4
Elena Ionata, Loredana Marcolongo, Francesco La Cara, Giovanni P Cetrangolo, Ferdinando Febbraio
In this work, a new exploitation of the thermostable β-glycosidase from Sulfolobus solfataricus expressed in Saccharomyces cerevisiae to create functional foods for low lactose diets was evaluated. For this purpose, the lactose hydrolysis reaction using immobilized and soluble enzymes was investigated. Activity and stability at different conditions of pH and temperature were tested. The immobilization process had a big impact on the catalysis performance, leading to an enhancement of the enzymatic reaction rate on lactose, as demonstrated by the increasing of 2 and 2...
April 2, 2018: Biopolymers
https://www.readbyqxmd.com/read/29505134/one-third-of-children-with-lactose-intolerance-managed-to-achieve-a-regular-diet-at-the-three-year-follow-up-point
#5
Anat Yerushalmy-Feler, Hagai Soback, Ronit Lubetzky, Amir Ben-Tov, Margalit Dali-Levy, Tut Galai, Shlomi Cohen
AIM: This study described outcomes following treatment for lactose intolerance, which is common in children. METHODS: The medical records of children aged 6-18 years who underwent lactose hydrogen breath testing at Dana-Dwek Children's Hospital, Tel Aviv, Israel, from August 2012 to August 2014 were analysed. We compared 154 children with gastrointestinal symptoms and positive lactose hydrogen breath tests to 49 children with negative test results. RESULTS: Of the 154 children in the study group, 89 (57...
March 5, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29425071/the-effects-of-probiotics-in-lactose-intolerance-a-systematic-review
#6
Sophia J Oak, Rajesh Jha
Over 60 percent of the human population has a reduced ability to digest lactose due to low levels of lactase enzyme activity. Probiotics are live bacteria or yeast that supplements the gastrointestinal flora. Studies have shown that probiotics exhibit various health beneficial properties such as improvement of intestinal health, enhancement of the immune responses, and reduction of serum cholesterol. Accumulating evidence has shown that probiotic bacteria in fermented and unfermented milk products can be used to alleviate the clinical symptoms of lactose intolerance (LI)...
February 9, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29421696/purification-and-characterization-of-%C3%AE-galactosidase-from-probiotic-pediococcus-acidilactici-and-its-use-in-milk-lactose-hydrolysis-and-galactooligosaccharide-synthesis
#7
Preeti Chanalia, Dimpi Gandhi, Pooja Attri, Suman Dhanda
β-galactosidase is a commercially important enzyme that was purified from probiotic Pediococcus acidilactici. The enzyme was extracted from cells using sonication and subsequently purified using ammonium sulphate fractionation and successive chromatographies on Sephadex G-100 and Q-Sepharose. The enzyme was purified 3.06-fold up to electrophoretic homogeneity with specific activity of 0.883 U/mg and yield of 28.26%. Molecular mass of β-galactosidase as estimated by SDS-PAGE and MALDI-TOF was 39.07 kDa. The enzyme is a heterodimer with subunit mass of 15...
April 2018: Bioorganic Chemistry
https://www.readbyqxmd.com/read/29384557/the-association-between-adult-type-hypolactasia-and-symptoms-of-functional-dyspepsia
#8
André Castagna Wortmann, Daniel Simon, Luiz Edmundo Mazzoleni, Guilherme Becker Sander, Carlos Fernando de Magalhães Francesconi, Débora Dreher Nabinger, Camila Schultz Grott, Tássia Flores Rech, Felipe Mazzoleni, Vagner Ricardo Lunge, Laura Renata de Bona, Tobias Cancian Milbradt, Themis Reverbel da Silveira
Functional dyspepsia and lactose intolerance (adult-type hypolactasia, ATH) are common conditions that may coexist or even be confounded. Their clinical presentation can be similar, however, lactose intolerance does not form part of the diagnostic investigation of functional dyspepsia. Studies on the association between functional dyspepsia and ATH are scarce. This study aimed to evaluate whether ATH is associated with symptoms of functional dyspepsia. Patients fulfilling the Rome III diagnostic criteria for functional dyspepsia underwent genetic testing for ATH...
January 2018: Genetics and Molecular Biology
https://www.readbyqxmd.com/read/29379537/hydrogen-excretion-in-pediatric-lactose-malabsorbers-relation-to-symptoms-and-the-dose-of-lactose
#9
Katarzyna Pawłowska, Rafał Seredyński, Wioleta Umławska, Barbara Iwańczak
Introduction: Lactose malabsorption arises from lactase deficiency and may lead to lactose intolerance - gastrointestinal symptoms after lactose ingestion. Occurrence and severity of the symptoms are influenced by many factors, including the dose of lactose and the intensity of its colonic fermentation to short chain fatty acids and gases. Material and methods: The hydrogen breath test (HBT) after 30 g or 50 g of lactose was performed in 387 children. Further analysis included children who had a positive HBT result...
January 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29358791/how-well-do-plant-based-alternatives-fare-nutritionally-compared-to-cow-s-milk
#10
REVIEW
Sai Kranthi Vanga, Vijaya Raghavan
Due to the issues like lactose intolerance and milk allergy arising from the consumption of cow's milk, there has been an increased demand in the plant based alternative milks around the world. Food industry has addressed these demands by introducing various milk beverages which are promoted as alternatives coming from plant sources which include almond milk and soy milk. Though they are popularly advertised as healthy and wholesome, little research has been done in understanding the nutritional implications of consuming these milk beverages in short term and long term...
January 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29303109/-protocols-related-to-food-allergies-and-intolerances-in-preschools-in-reykjavik-iceland
#11
Adalheidur Ran Thrastardottir, Frida Run Thordardottir, Johanna Torfadottir
INTRODUCTION: The aim of the study was to explore prevalence of food allergies and intolerances among children in preschools in Reykjavik, Iceland. Also, to investigate how well preschools maintain a safe environment for children with food allergies. MATERIALS AND METHODS: In 2014, a questionnaire designed specifically for this study, was sent to 65 preschools. Forty-nine participated (75%) representing a total of 4225 children. Prevalence of food allergy and intolerance was determined based on medical certificates from physi-cians delivered to the preschools...
January 2018: Læknablađiđ
https://www.readbyqxmd.com/read/29282192/mast-cell-activation-syndrome
#12
Owen N Kramer, Marla S Barkoff, Claudia Hernandez
A 51-year-old woman with a history of asthma and Hashimoto's thyroiditis presented to the dermatology service with a chief complaint of "itchy bumpy rashes" that persisted beyond 24 hours. She noted that, 3 days prior to the onset of urticaria, a pyrroloquinoline quinone supplement had been started. The urticaria was accompanied by variable episodes of transient facial swelling and difficulty breathing. The patient noted that exposure to fish, nuts, and nonsteroidal anti-inflammatory drugs triggered facial swelling...
2017: Skinmed
https://www.readbyqxmd.com/read/29241218/analysis-of-the-cariogenic-potential-of-various-almond-milk-beverages-using-a-streptococcus-mutans-biofilm-model-in-vitro
#13
Janelle Lee, Janice A Townsend, Tatyana Thompson, Thomas Garitty, Arpan De, Qingzhao Yu, Brian M Peters, Zezhang T Wen
To evaluate the cariogenic properties of almond milk beverages, 6 almond milks, along with soy and whole bovine milk, were analyzed for their abilities to support Streptococcus mutans biofilm formation and acid production, and their capacity to buffer changes in pH. Biofilm formation by S. mutans was analyzed using an in vitro 96-well plate model and measured by crystal violet staining. Acid production by S. mutans was evaluated by a colorimetric L-lactate assay and pH measurement of bacterial cultures. Buffering capacity was assessed by a pH titration assay...
2018: Caries Research
https://www.readbyqxmd.com/read/29222879/prevalence-cause-and-diagnosis-of-lactose-intolerance-in-children-aged-1-5-years-a-systematic-review-of-1995-2015-literature
#14
Louise Harvey, Thomas Ludwig, Alice Qian Hou, Quak Seng Hock, Michelle Ln Tan, Seksit Osatakul, Jacques Bindels, Leilani Muhardi
BACKGROUND AND OBJECTIVES: To assess the prevalence, etiology, diagnosis of primary and secondary lactose intolerance (LI), including age of onset, among children 1-5 years of age. Suspected/perceived lactose intolerance can lead to dietary restrictions which may increase risk of future health issues. METHODS AND STUDY DESIGN: MEDLINE, CAB Abstract, and Embase were searched for articles published from January 1995-June 2015 related to lactose intolerance in young children...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29181545/non-celiac-gluten-sensitivity-people-without-celiac-disease-avoiding-gluten-is-it-due-to-histamine-intolerance
#15
REVIEW
Wolfgang J Schnedl, Sonja Lackner, Dietmar Enko, Michael Schenk, Harald Mangge, Sandra J Holasek
INTRODUCTION: Food intolerance/malabsorption is caused by food ingredients, carbohydrates (mainly lactose and fructose), proteins (gluten), and biogenic amines (histamine) which cause nonspecific gastrointestinal and extra-intestinal symptoms. Here we focus on possible etiologic factors of intolerance/malabsorption especially in people with non-celiac gluten sensitivity (NCGS) or the so-called people without celiac disease avoiding gluten (PWCDAG) and histamine intolerance. METHODS: Recognizing the recently described symptoms of NCGS (PWCDAG) we review correlations and parallels to histamine intolerance (HIT)...
April 2018: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/29159163/association-of-lct-13910-c-t-polymorphism-and-colorectal-cancer
#16
Genco Gençdal, Esin Salman, Ömer Özütemiz, Ulus S Akarca
Purpose: The activity of epithelial lactase (LCT) is associated with a polymorphism 13910 bp upstream in the lactase encoding gene. Because the association between the LCT-13910 polymorphism and the risk for colorectal cancer is not clear, we investigated the role of the LCT-13910 polymorphism as a potential risk factor for colorectal cancer and colorectal polyps in the Turkish population. Methods: One hundred sixty-six subjects (74 with polyps, 44 with colorectal cancer, 48 controls), who had undergone a total colonoscopy between January 2012 and November 2012 in our endoscopy unit were genotyped for the LCT-13910 polymorphism by using the polymerase chain reaction and minisequencing...
October 2017: Annals of Coloproctology
https://www.readbyqxmd.com/read/29159160/lactose-intolerance-and-colorectal-cancer
#17
EDITORIAL
Jong-Woo Kim
No abstract text is available yet for this article.
October 2017: Annals of Coloproctology
https://www.readbyqxmd.com/read/29157302/prevalence-of-lactose-intolerance-in-patients-with-diarrhea-predominant-irritable-bowel-syndrome-data-from-a-tertiary-center-in-southern-china
#18
Lishou Xiong, Yilin Wang, Xiaorong Gong, Minhu Chen
BACKGROUND: Symptoms associated with lactose intolerance (LI) and diarrhea-predominant irritable bowel syndrome (IBS-D) are almost the same. These disease entities are difficult to differentiate clinically. In practice, differential diagnosis depends on self-reported patient milk intolerance. However, there is limited data on the prevalence of LI in China. The aim of this study was to investigate the prevalence of LI in IBS-D patients and asymptomatic healthy controls. METHODS: Lactose malabsorption (LM) was diagnosed by a lactose hydrogen breath test (HBT) and was defined by peak breath H2 excretion over the baseline level of ≥ 20 ppm...
November 21, 2017: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/29124021/allele-specific-lamp-gold-nanoparticle-for-characterization-of-single-nucleotide-polymorphisms
#19
Fábio Ferreira Carlos, Bruno Veigas, Ana S Matias, Gonçalo Doria, Orfeu Flores, Pedro V Baptista
Due to their relevance as disease biomarkers and for diagnostics, screening of single nucleotide polymorphism (SNPs) requires simple and straightforward strategies capable to provide results in medium throughput settings. Suitable approaches relying on isothermal amplification techniques have been evolving to substitute the cumbersome and highly specialized PCR amplification detection schemes. Nonetheless, identification of an individual's genotype still requires sophisticated equipment and laborious methods...
December 2017: Biotechnology Reports
https://www.readbyqxmd.com/read/29070042/effects-of-cow-s-milk-beta-casein-variants-on-symptoms-of-milk-intolerance-in-chinese-adults-a-multicentre-randomised-controlled-study
#20
Mei He, Jianqin Sun, Zhuo Qin Jiang, Yue Xin Yang
BACKGROUND: A major protein component of cow's milk is β-casein. The most frequent variants in dairy herds are A1 and A2. Recent studies showed that milk containing A1 β-casein promoted intestinal inflammation and exacerbated gastrointestinal symptoms. However, the acute gastrointestinal effects of A1 β-casein have not been investigated. This study compared the gastrointestinal effects of milk containing A1 and A2 β-casein versus A2 β-casein alone in Chinese adults with self-reported lactose intolerance...
October 25, 2017: Nutrition Journal
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