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https://www.readbyqxmd.com/read/28098509/-compassionate-use-protocol-for-auditory-brainstem-implantation-in-neurofibromatosis-type-2-early-house-ear-institute-experience
#1
Daniel S Roberts, William H Slattery, Brian S Chen, Steve R Otto, Marc S Schwartz, Gregory P Lekovic
OBJECTIVE: To report the preliminary outcomes of auditory brainstem implantation (ABI) under a compassionate use protocol for two ABI devices that are not approved by the US Food and Drug Administration. METHODS: A retrospective review was performed of neurofibromatosis type 2 (NF2) patients who underwent microsurgery for vestibular schwannoma (VS) and placement of either the Cochlear ABI541 or Med-El Synchrony ABIs. Peri-operative and device- related complications were reviewed...
January 18, 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/28096828/intramural-esophageal-tumors
#2
Mariusz P Łochowski, Katarzyna Kozak, Marek Rębowski, Józef Kozak
INTRODUCTION: Intramural esophageal tumors (IET) are located between unchanged mucous membrane and muscularis mucosae. They can be both benign and malignant. AIM: To evaluate diagnostic and therapeutic difficulties of IET. MATERIAL AND METHODS: During the years 2010-2015, 11 patients with IET were treated in our clinic. Diagnostics included gastroscopy, computed tomography of the chest, endoscopic ultrasound (EUS) guided fine needle biopsy, and positron emission tomography (PET) of the esophagus in cases with no histopathological confirmation...
December 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28096224/supra-and-infratentorial-ectopic-schwannoma-mimicking-a-meningioma
#3
Pedro Ribeiro da Cunha, José Luís Alves, Armando Rocha
We report the case of a supra and infratentorial ectopic schwannoma, mimicking a meningioma, that was surgically resected on a 75-year-old man, with a history of progressive visual loss and headaches. MRI was in favour of an occipital, cystic, tentorial-based meningioma extending to the posterior fossa, with signs of intratumoral haemorrhage. This is a unique case because of the rare type of lesion, in a very atypical location, completely unexpected by the preoperative imaging analysis, and to the best of our knowledge it is the oldest patient reported in the literature with this kind of tumour...
January 17, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28095610/uveal-schwannoma-in-a-brown-eyed-dog
#4
Todd L Marlo, Elizabeth A Giuliano, Cecil P Moore, Gillian C Shaw, Leandro B C Teixeira
An eleven-year-old, female spayed Boxer dog was diagnosed with a uveal schwannoma (formerly known as the spindle cell tumor of the blue-eyed dog or SCTBED) despite having a uniformly brown iris. The patient presented to emergency for ocular discomfort, and the right globe was subsequently enucleated due to glaucoma and submitted for histopathology. Upon histopathologic evaluation, a uveal schwannoma was diagnosed and confirmed with immunohistochemical staining. Complete metastatic evaluation 1 and 6 months after initial presentation did not reveal evidence of metastasis, and the dog remains systemically healthy...
January 17, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/28090635/sonographic-features-and-diagnosis-of-peripheral-schwannomas
#5
Fan Yang, Xian-Xiang Chen, Huo-Lin Wu, Ji-Fa Zhu, Yuan Chen, Ling-Fang Yu, Xiao-Juan Huang
BACKGROUND: To determine the sonographic features of peripheral schwannomas. METHODS: This retrospective study included 54 cases of schwannoma in 51 patients. Ultrasonography (US) and MRI were performed in all patients. The US features of each tumor were analyzed and compared with pathologic findings. The US target sign was compared with the MRI findings. RESULTS: On US, 53 of the 54 schwannomas had a regular shape and clear margins, and one had an irregular shape...
January 16, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28089525/radiotherapeutic-management-of-vestibular-schwannomas-using-size-and-location-adapted-fractionation-regimens-to-maximize-the-therapeutic-ratio
#6
Benjamin G Slane, Uma Goyal, Joel L Grow, Christopher Morrison, Craig R Hullet, John Gordon, Abhay Sanan, Baldassarre Stea
BACKGROUND: We evaluated and compared the radiographic and clinical outcomes of patients with vestibular schwannomas treated with single fraction stereotactic radiosurgery (SRS), 5 fractions of hypofractionated stereotactic radiation therapy (hSRT), or 25 to 30 fractions of conventionally fractionated stereotactic radiation therapy (cfSRT). METHODS AND MATERIALS: Fifty-six patients treated with LINAC-based SRS (median, 12.5 Gy), hSRT (25 Gy), or cfSRT (median, 54 Gy) were retrospectively reviewed...
October 28, 2016: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28079677/cadaveric-testing-of-robot-assisted-access-to-the-internal-auditory-canal-for-vestibular-schwannoma-removal
#7
Neal P Dillon, Ramya Balachandran, Michael A Siebold, Robert J Webster, George B Wanna, Robert F Labadie
HYPOTHESIS: An image-guided robotic system can safely perform the bulk removal of bone during the translabyrinthine approach to vestibular schwannoma (VS). BACKGROUND: The translabyrinthine approach to VS removal involves extensive manual milling in the temporal bone to gain access to the internal auditory canal (IAC) for tumor resection. This bone removal is time consuming and challenging due to the presence of vital anatomy (e.g., facial nerve) embedded within the temporal bone...
January 10, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28078568/rediagnosing-one-of-smith-s-patients-john-mccann-with-neuromas-tumours-1849
#8
Martino Ruggieri, Andrea D Praticò, Rosario Caltabiano, Agata Polizzi
In 1849, the Irish Professor of Surgery, Sir Robert William Smith, by publishing his "Treatise on the Pathology, Diagnosis and Treatment of Neuroma", collected six previous examples of "general development of neuromatous tumours" and reported three further cases (two personal and one referred) of what is nowadays known as neurofibromatosis. Among these latter cases, there was a 35-year-old cattle-driver, John McCann, who was first admitted at hospital in 1840 because of a large tumour on the right side of his neck thought to be malignant (and a second tumour sublingually) but not operated...
January 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28078405/-radiosurgery-and-fractionated-stereotactic-radiotherapy-of-vestibular-schwannoma
#9
K Hamm, H-U Herold, G Surber, S Rosahl
Management of vestibular schwannoma (VS) should always be interdisciplinary and results better than the natural course. Particularly in small VS, either microsurgical resection or radiosurgery (RS) can be employed. RS is a special method (initially only possible stereotactically) for delivering high-precision radiation from many directions to the target point (the isocenter) in a single high dose. With the development of three different systems-Gamma Knife (Elekta, Stockholm, Sweden), special linear accelerators, and CyberKnife (Accuray, Sunnyvale, CA, USA)-the options were extended to 1-5 fractions for RS and multisession RS (msRS), and to up to 6 weeks of conventional fractionation as stereotactic radiotherapy (SRT)...
January 11, 2017: HNO
https://www.readbyqxmd.com/read/28072654/adverse-events-following-vestibular-schwannoma-surgery-a-comparison-of-surgical-approach
#10
Anthony M Tolisano, Philip D Littlefield
OBJECTIVE: Compare complications of vestibular schwannoma (VS) resection by surgical approach. STUDY DESIGN: Retrospective cohort. SETTING: The 2008 to 2013 American College of Surgeons-National Surgical Quality Improvement Program. PATIENTS: Adult patients with VS resection by an otolaryngologist. INTERVENTIONS: VS resection via transtemporal (TT), retrosigmoid (RS), or middle cranial fossa (MCF) approaches...
January 9, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28069420/the-authors-herby-confirm-that-this-manuscript-has-neither-been-published-nor-submitted-to-any-other-journal-confocal-laser-endomicroscopy-in-neurosurgery-an-alternative-to-instantaneous-sections
#11
David Breuskin, Jacek Szczygielski, Steffi Urbschat, Yoo-Jin Kim, Joachim Oertel
INTRODUCTION: Intraoperative distinction of brain tumor from the surround brain is one of the crucial challenges in neurooncological surgery. In this study, confocal laser endomicroscope (CLE) findings were directly compared with intraoperative instantaneous sections by the neuropathologist in a blinded fashion. MATERIAL AND METHODS: The imaging device comprises of a rigid endoscope with Hopkins-Rod lenses and a red wave length laser with a scanning depth of 80 μm...
January 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28068303/delayed-vestibular-schwannoma-regrowth-following-shrinkage-after-stereotactic-radiosurgery-implication-for-life-long-surveillance
#12
Emma Stapleton, John A Crowther, Richard Locke, Georgios Kontorinis
OBJECTIVE: To enhance understanding of the behavior of vestibular schwannomas (VS) after stereotactic radiosurgery (SRS), including the potential for late tumor regrowth, and the need for lifelong radiological and clinical surveillance. PATIENTS: From a total of 540 patients with VS and out of 95 patients receiving SRS for their growing VS, the cases of two women patients aged 58 and 59 years with medium sized, growing VS are presented. INTERVENTION: Both patients were treated with SRS...
February 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28067722/-neutrophil-to-lymphocyte-ratio-as-a-predictive-marker-of-vestibular-schwannoma-growth-otology-neurotology-2016-37-580-5
#13
Satvinder Singh Bakshi
No abstract text is available yet for this article.
February 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28060689/-schwannoma-of-the-upper-extremity-retrospective-analysis-of-17-cases
#14
Ângelo Sá, Leandro Nobre Azevedo, Luísa Cunha
INTRODUCTION: Schwannoma or neurilemmoma is a benign peripheric nerve tumor that usually presents as a slow growing single lesion; it has origin in Schwann cells proliferation. Although it represents a small percentage of the benign tumors of the upper arm, it is the most frequent of neural origin. We present a retrospective study of upper limb schwannomas; our aim is establish the appropriate preoperative approach, to recognise the efficiency of the treatment and the pos-operative follow-up...
September 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28058466/-malignization-of-vestibular-schwannoma-13%C3%A2-years-after-radiation-therapy
#15
S Simmermacher, D Vordermark, T Kegel, C Strauss
This article presents a case of malignant transformation of vestibular schwannoma 13 years after stereotactic radiation therapy, which lead to an acute life-threatening condition. Although the observation is currently only based on case reports, an increasing number of these support the hypothesis that there is a relevant risk of malignant transformation in the long-term course of previously irradiated vestibular schwannomas. Therefore, long-term MRI follow-up should be considered.
January 5, 2017: HNO
https://www.readbyqxmd.com/read/28050327/isolated-schwannoma-of-the-upper-eyelid-margin-in-a-50-year-old-male
#16
Mehmet Serdar Dervişoğulları, Yüksel Totan, Ümran Yıldırım
Schwannomas (neurilemmomas) are benign neurogenic tumours of peripheral nerves. They originate from Schwann cells, which form the neural sheath. Although Schwannomas and neurofibromas are the most common primary peripheral nerve tumours, Schwannomas are rarely observed in ophthalmic areas. When they occur, ocular Schwannomas are usually located in the orbit, uveal tract and conjunctiva. Isolated eyelid Schwannomas are reported infrequently. Herein, we describe a case of eyelid Schwannoma in a 50-year-old man...
December 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28049116/schwannoma-of-the-tongue
#17
Jakob Kavčič, Marko Božič
Schwannoma, neurilemmoma or neurinoma is a rare, benign nerve sheath neoplasm composed of Schwann cells. It is usually solitary, slow growing and asymptomatic. Approximately 1-12% of the tumours occur intraorally with the tongue being the most common location. We report a rare case of lingual schwannoma in a 20-year-old female patient involving the tip of the tongue, which was slow growing and asymptomatic. For diagnosis histopathological examination and also immunohistochemistry testing were carried out to confirm the nature of tissue fragments...
October 8, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/28047111/su-f-t-611-critical-analysis-and-efficacy-of-linac-based-beam-modulator-and-cyberknife-treatment-plans-for-acoustic-neuroma-schwannoma
#18
Karrthick Kp, T Kataria, R Thiyagarajan, T Selvan, A Abhishek
PURPOSE: To study the critical analysis and efficacy of Linac and Cyberknife (CK) treatment plans for acoustic neuroma/schwannoma. METHODS: Twelve of acoustic neuroma/schwannoma patients were taken for these study that. Treatment plans were generated in Multiplan treatment planning system (TPS) for CK using 5,7.5 and 10mm diameter collimators. Target volumes were in the range of 0.280 cc to 9.256 cc. Prescription dose (Rx) ranges from 1150cGy to 1950cGy delivered over 1 to 3 Fractions...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046895/su-f-t-648-sharpening-dose-fall-off-via-beam-number-enhancements-for-stereotactic-brain-radiosurgery
#19
J Chiu, M Pierce, S Braunstein, M McDermott, P Sneed, L Ma
PURPOSE: Sharp dose fall-off is the hallmark of brain radiosurgery to deliver a high dose of radiation to the target while minimizing dose to normal brain tissue. In this study, we developed a technique for the purpose of enhancing the peripheral dose gradient by magnifying the total number of beams focused toward each isocenter via patient head tilt and simultaneous beam intensity modulations. METHODS: Computer scripting for the proposed beam number enhancement (BNE) technique was developed...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045630/outcomes-of-vestibular-schwannoma-surgery-among-the-elderly
#20
Michael J Sylvester, Darshan N Shastri, Viral M Patel, Milap D Raikundalia, Jean Anderson Eloy, Soly Baredes, Yu-Lan Mary Ying
Objective To compare comorbidities and in-hospital complications between elderly and nonelderly patients undergoing vestibular schwannoma (VS) surgery. To examine average length of stay (LOS) and hospital charges among elderly patients. Study Design Population-based inpatient registry analysis. Setting Academic medical center. Subjects and Methods Retrospective analysis of the National Inpatient Sample for patients undergoing VS surgery from 2002 to 2010: 4137 patients met inclusion criteria, with 519 (12.5%) in the elderly cohort (≥65 years)...
January 2017: Otolaryngology—Head and Neck Surgery
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