Fahima Moosa, Mignon du Plessis, Michael R Weigand, Yanhui Peng, Dineo Mogale, Linda de Gouveia, Marta C Nunes, Shabir A Madhi, Heather J Zar, Gary Reubenson, Arshad Ismail, M Lucia Tondella, Cheryl Cohen, Sibongile Walaza, Anne von Gottberg, Nicole Wolter
Pertussis remains a public health concern in South Africa, with an increase in reported cases and outbreaks in recent years. Whole genome sequencing was performed on 32 Bordetella pertussis isolates sourced from three different surveillance programmes in South Africa between 2015 and 2019. Genome sequences were characterized using multilocus sequence typing, vaccine antigen genes ( ptxP , ptxA , ptxB , prn and fimH ) and overall genome structure. All isolates were sequence type 2 and harboured the pertussis toxin promoter allele ptxP3 ...
December 2023: Microbial Genomics