Jeremy S Treger, Ahmad B Allaw, Pouyan Razminia, Dipayon Roy, Amulya Gampa, Swati Rao, Andrew D Beaser, Srinath Yeshwant, Zaid Aziz, Cevher Ozcan, Gaurav A Upadhyay
IMPORTANCE: Current left bundle branch block (LBBB) criteria are based on animal experiments or mathematical models of cardiac tissue conduction and may misclassify patients. Improved criteria would impact referral decisions and device type for cardiac resynchronization therapy. OBJECTIVE: To develop a simple new criterion for LBBB based on electrophysiological studies of human patients, and then to validate this criterion in an independent population. DESIGN, SETTING, AND PARTICIPANTS: In this diagnostic study, the derivation cohort was from a single-center, prospective study of patients undergoing electrophysiological study from March 2016 through November 2019...
March 27, 2024: JAMA Cardiology