keyword
https://read.qxmd.com/read/38473055/management-of-donkeys-in-assisted-interventions-a-snapshot
#21
JOURNAL ARTICLE
Lucia Sobrero, Emanuela Dalla Costa, Michela Minero
People working in the field of Animal-Assisted Interventions (AAIs) often state that they perceive animal welfare as a matter of paramount importance; nevertheless, most scientific literature focuses on the effectiveness of interventions from the user's perspective. Before focusing on the animals' management and welfare during their interactions with users, it is important to ensure animal welfare during their "ordinary lives". This article reports information and considerations about the management of donkeys involved in AAIs in Northern Italy...
February 21, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38442174/in-situ-formed-depot-of-elastin-like-polypeptide-hirudin-fusion-protein-for-long-acting-antithrombotic-therapy
#22
JOURNAL ARTICLE
Xue Tian, Mingxing Feng, Xinwei Wei, Cheng Cheng, Kaixin He, Tianyue Jiang, Bingfang He, Zhen Gu
Thrombosis, induced by abnormal coagulation or fibrinolytic systems, is the most common pathology associated with many life-threatening cardio-cerebrovascular diseases. However, first-line anticoagulant drugs suffer from rapid drug elimination and risk of hemorrhagic complications. Here, we developed an in situ formed depot of elastin-like polypeptide (ELP)-hirudin fusion protein with a prodrug-like feature for long-term antithrombotic therapy. Highly secretory expression of the fusion protein was achieved with the assistance of the Ffu312 tag...
March 12, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38439108/culture-of-hoffa-fat-pad-mesenchymal-stem-stromal-cells-on-microcarrier-suspension-in-vertical-wheel-bioreactor-for-extracellular-vesicle-production
#23
JOURNAL ARTICLE
Alexander Otahal, Karina Kramer, Markus Neubauer, Slavomira Gulová, Zsombor Lacza, Stefan Nehrer, Andrea De Luna
BACKGROUND: Mesenchymal stromal cells (MSCs) are increasingly employed in regenerative medicine approaches for their immunomodulatory and anti-inflammatory properties, which are encoded in their secretome including extracellular vesicles (EVs). The Hoffa fat pad (HFP) located infrapatellarly harbours MSCs that could assist in tissue homeostasis in osteoarthritic joints. Intraarticular injection therapies based on blood products could modulate the populations of released HFP-MSC-EVs in a quantitative manner...
March 5, 2024: Stem Cell Research & Therapy
https://read.qxmd.com/read/38424039/magnetically-driven-capsules-with-multimodal-response-and-multifunctionality-for-biomedical-applications
#24
JOURNAL ARTICLE
Yuxuan Sun, Wang Zhang, Junnan Gu, Liangyu Xia, Yinghao Cao, Xinhui Zhu, Hao Wen, Shaowei Ouyang, Ruiqi Liu, Jialong Li, Zhenxing Jiang, Denglong Cheng, Yiliang Lv, Xiaotao Han, Wu Qiu, Kailin Cai, Enmin Song, Quanliang Cao, Liang Li
Untethered capsules hold clinical potential for the diagnosis and treatment of gastrointestinal diseases. Although considerable progress has been achieved recently in this field, the constraints imposed by the narrow spatial structure of the capsule and complex gastrointestinal tract environment cause many open-ended problems, such as poor active motion and limited medical functions. In this work, we describe the development of small-scale magnetically driven capsules with a distinct magnetic soft valve made of dual-layer ferromagnetic soft composite films...
February 29, 2024: Nature Communications
https://read.qxmd.com/read/38412931/trends-in-stroke-related-journals-examination-of-publication-patterns-using-topic-modeling
#25
JOURNAL ARTICLE
Burak Berksu Ozkara, Mert Karabacak, Konstantinos Margetis, Wade Smith, Max Wintermark, Vivek Srikar Yedavalli
OBJECTIVES: This study aims to demonstrate the capacity of natural language processing and topic modeling to manage and interpret the vast quantities of scholarly publications in the landscape of stroke research. These tools can expedite the literature review process, reveal hidden themes, and track rising research areas. MATERIALS AND METHODS: Our study involved reviewing and analyzing articles published in five prestigious stroke journals, namely Stroke, International Journal of Stroke, European Stroke Journal, Translational Stroke Research, and Journal of Stroke and Cerebrovascular Diseases...
February 25, 2024: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://read.qxmd.com/read/38410868/being-in-a-meaningful-context-nature-and-animal-assisted-activities-as-perceived-by-adults-with-autism
#26
JOURNAL ARTICLE
A Birgitta Gunnarsson, Ingrid Edvardsson Aurin, Sara Holmberg
INTRODUCTION: Animal-assisted and nature-based interventions in psychosocial treatment for various groups of clients have been studied internationally. However, there is little knowledge about how young adults with autism experience participation in such types of interventions. This clinical study aimed to describe the feasibility of animal-assisted and nature-based activities on a farm as a complementary intervention for young adults with autism and social withdrawal. METHODS: The participants were aged 18-30 years, diagnosed with autism and social withdrawal, with no organised occupation during the previous year...
February 27, 2024: Australian Occupational Therapy Journal
https://read.qxmd.com/read/38404545/penile-fibrosis-still-scarring-urologists-today-a-narrative-review
#27
REVIEW
Raul E Fernandez Crespo, Florian Stroie, Laura Taylor, Michael Pignanelli, Justin Parker, Rafael Carrion
BACKGROUND AND OBJECTIVE: Implantation of penile prosthesis (PP) into scarred and fibrotic corpora can be a difficult challenge. In this review article, we provide a review of penile fibrosis, discuss current medical and surgical management and summarize preventative strategies. METHODS: In this study, we searched PubMed between the years 2000-2023 for publications with search strategy: "penile fibrosis" OR "scarred corpora" OR "fibrosed corpora". KEY CONTENT AND FINDINGS: This search returned a total of 137 articles...
January 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38396572/a-relaxed-horse-a-relaxed-client-an-experimental-investigation-of-the-effects-of-therapy-horses-stress-on-clients-stress-mood-and-anxiety
#28
JOURNAL ARTICLE
Alicia Müller-Klein, Moritz Nicolai Braun, Diana S Ferreira de Sá, Tanja Michael, Ulrike Link-Dorner, Johanna Lass-Hennemann
Equine-assisted therapies are becoming increasingly popular for addressing physical and psychological disabilities in clients. The role of the horse's welfare in equine-assisted service receives increasing attention in research. Several studies have shown that horses are able to perceive human emotions and respond to human stress responses. However, no research has yet looked at the other side of the coin-whether and how humans perceive and react to equine stress levels during equine-assisted services. To fill this gap in the research, we employed a within-subjects design, in which horse-naïve participants had a standardized interaction with both an experimentally stressed horse and an experimentally relaxed horse...
February 13, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38396504/the-behavioral-cost-of-care-changes-in-maintenance-behavior-during-equine-assisted-interventions
#29
JOURNAL ARTICLE
Angela K Fournier, Megan French, Elizabeth A Letson, Joy Hanson, Thomas D Berry, Sarah Cronin
This study examined human-animal symbiosis in an animal-assisted intervention through observations of animal maintenance behaviors. The rise of psychotherapy, learning, and recreation incorporating animals warrants exploration of the welfare of the animals involved in these interventions. The analysis of welfare in multispecies engagements can be discussed in terms of symbiosis. Regarding an intervention's animal provider (e.g., therapy horse) and human recipient (psychotherapy client), the balance of cost and benefit is important...
February 6, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38386471/animal-assisted-therapy-in-pediatric-autism-spectrum-disorder-a-case-report
#30
JOURNAL ARTICLE
Michele Kilmer, Minju Hong, Danielle Randolph, Allison Reichel, Sarah Huetter, Madelyn Bowden, Clay Kilmer
The use of therapy or service dogs to assist children with autism spectrum disorder (ASD) is increasing in clinical settings. Research studies indicate that children with ASD display enhanced prosocial behavior and emotional regulation when canines are included in therapy. Despite increased application of animal-assisted therapy in clinical and inpatient settings, healthcare providers show limited understanding of best practices for its use and require a research-based approach to incorporate animals effectively into therapeutic plans of care for pediatric patients with ASD...
March 1, 2024: Nurse Practitioner
https://read.qxmd.com/read/38373634/clinical-features-of-pasteurellosis-without-an-animal-bite-or-scratch-in-comparison-with-bite-scratch-pasteurellosis
#31
JOURNAL ARTICLE
Tsubasa Asaeda, Takashi Ueda, Yasuhiro Nozaki, Yasushi Murakami, Mika Morosawa, Hiroko Inaba, Hitoshi Ogashiwa, Miki Doi, Kazuhiko Nakajima, Manabu Shirakawa, Akifumi Nakamura, Naoto Ikeda, Yuya Sugiyama, Yoshihiro Wada, Takahiro Ito, Yoshio Takesue
Pasteurellosis is a common zoonotic infection that occurs after an animal bite or scratch (B/S). We compared the clinical features of six patients with non-B/S pasteurellosis with those of 14 patients with B/S infections. Pasteurella multocida was identified with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry in all six non-B/S infections, whereas 13 of the 14 B/S infections were identified with diagnostic kits. The non-B/S infections were pneumonia (n = 3), skin and soft tissue infections (n = 2), and bacteremia (n = 1)...
February 17, 2024: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://read.qxmd.com/read/38367973/baby-habit-ile-intervention-study-protocol-of-a-randomised-controlled-trial-in-infants-aged-6-18-months-with-unilateral-cerebral-palsy
#32
JOURNAL ARTICLE
Astrid Carton de Tournai, Enimie Herman, Estelle Gathy, Daniela Ebner-Karestinos, Rodrigo Araneda, Laurence Dricot, Benoît Macq, Yves Vandermeeren, Yannick Bleyenheuft
INTRODUCTION: Research using animal models suggests that intensive motor skill training in infants under 2 years old with cerebral palsy (CP) may significantly reduce, or even prevent, maladaptive neuroplastic changes following brain injury. However, the effects of such interventions to tentatively prevent secondary neurological damages have never been assessed in infants with CP. This study aims to determine the effect of the baby Hand and Arm Bimanual Intensive Therapy Including Lower Extremities (baby HABIT-ILE) in infants with unilateral CP, compared with a control intervention...
February 17, 2024: BMJ Open
https://read.qxmd.com/read/38361478/the-yucatan-miniature-swine-as-a-model-for-post-inflammatory-hyperpigmentation
#33
JOURNAL ARTICLE
Ying Wang, Emilee Herringshaw, R Rox Anderson, Joshua Tam
Post-inflammatory hyperpigmentation (PIH) is a hypermelanosis that often occurs secondary to skin irritation or injury, especially in darker skin tones, for which there is currently a lack of effective treatment options. Few preclinical models are available to study PIH. Here, we show that the Yucatan miniature pig consistently develops PIH after skin injuries. Skin wounds were produced on Yucatan pigs by needle punches, full-thickness excisions, or burns. Wound sites were monitored and photographed regularly...
February 16, 2024: Pigment Cell & Melanoma Research
https://read.qxmd.com/read/38338052/how-to-measure-human-dog-interaction-in-dog-assisted-interventions-a-scoping-review
#34
REVIEW
Marta De Santis, Lorena Filugelli, Alberto Mair, Simona Normando, Franco Mutinelli, Laura Contalbrigo
Human-dog interaction is the working tool through which the therapeutic, educational and recreational goals of dog-assisted interventions (DAIs) are achieved. A better understanding of the characteristics of this interaction could improve the effectiveness of DAIs. This scoping review addresses the question: how has the human-dog connection been measured in the context of DAIs? After searching the Web of Science and Scopus platforms, only peer-reviewed, primary research studies reporting measures of therapy dog-human interaction, relationship and bond were included...
January 26, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38320424/postural-balance-control-interventions-in-autism-spectrum-disorder-asd-a-systematic-review
#35
REVIEW
Surabhi Date, Emily Munn, Georgia C Frey
BACKGROUND: Postural control (PC) disturbances in autism spectrum disorder (ASD) are associated with its severity. Varied sensorimotor interventions have been used for the management of these symptoms. However, there is a lack of a review elucidating all the available postural control interventions in ASD. RESEARCH QUESTION: To comprehensively present the variety of interventions targeted at improving PC in ASD and to provide future research recommendations. METHODS: PubMed, SCOPUS, Embase, Cochrane, ScienceDirect and Web of Science databases were searched for publications examining the effects of PC targeting interventions in those with ASD...
February 1, 2024: Gait & Posture
https://read.qxmd.com/read/38311676/positive-end-expiratory-pressure-limits-inspiratory-effort-through-modulation-of-the-effort-to-drive-ratio-an-experimental-crossover-study
#36
JOURNAL ARTICLE
Hannes Widing, Mariangela Pellegrini, Elena Chiodaroli, Per Persson, Katarina Hallén, Gaetano Perchiazzi
BACKGROUND: How assisted spontaneous breathing should be used during acute respiratory distress syndrome is questioned. Recent evidence suggests that high positive end-expiratory pressure (PEEP) may limit the risk of patient self-inflicted lung injury (P-SILI). The aim of this study was to assess the effects of PEEP on esophageal pressure swings, inspiratory drive, and the neuromuscular efficiency of ventilation. We hypothesized that high PEEP would reduce esophageal pressure swings, regardless of inspiratory drive changes, by modulating the effort-to-drive ratio (EDR)...
February 5, 2024: Intensive Care Medicine Experimental
https://read.qxmd.com/read/38275806/an-exploratory-study-into-the-backgrounds-and-perspectives-of-equine-assisted-service-practitioners
#37
JOURNAL ARTICLE
Rita Seery, Deborah Wells
Equine-Assisted Services (EASs) are commonplace in today's society, but vary widely in both theoretical and practical applications. Until now, practitioners' experiences and perspectives in relation to these services have received little attention. To address this, a purpose-designed online questionnaire was distributed to EAS practitioners, exploring issues relating to the nature of the service provided, practice patterns, practitioner education, perceived knowledge, challenges faced and the future direction of these services...
January 22, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38269565/-impact-of-animal-assisted-therapy-on-well-being-in-patients-with-alzheimer-s-disease-eliaut-study
#38
JOURNAL ARTICLE
Eline Thirion, Solveig Rouissi, Virginie Dauphinot, Antoine Garnier-Crussard, Marie-Hélène Coste, Pierre Krolak-Salmon
The development of non-pharmacological interventions, including animal-assisted therapy (AAT), is an encouraging method for the care of people with Alzheimer's disease (AD). A single-center, randomized, single-blind, controlled intervention study was proposed to compare immediate well-being measured by a visual analog scale (EVIBE) as primary outcome between the intervention group (AAT combined with cognitive stimulation) and the control group (cognitive stimulation only) in AD patients. Secondary outcomes were explored, such as well-being after intervention (also with the EVIBE), cognitive performance (measured by Alzheimer's Disease Assessment Scale, cognitive part GRECO version), behavioral and psychological symptoms of dementia (with the Neuropsychiatric Inventory Behavioral Scale-Nursing Home Version), current depressive symptomatology (with the 30 items Geriatric Depression Scale [GDS 30]) and anxiety (by the State-Trait Anxiety Inventory)...
December 1, 2023: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://read.qxmd.com/read/38254419/volunteer-engagement-within-equine-assisted-services
#39
JOURNAL ARTICLE
Aviva Vincent, Meghan Morrissey, Mary Acri, Fei Guo, Kimberly Hoagwood
This study examines the effect of volunteering within a Professional Association of Therapeutic Horsemanship International (PATH Intl) premiere accredited center by exploring the experiences of volunteers leading horses in adaptive riding lessons. Adaptive Riding lessons are horseback riding lessons for individuals ages four through the lifespan, with special needs, varying from cognitive, physical, social-emotional, or other challenges. Volunteers directly impact the rider-horse bond by increasing accessibility to horseback riding for individuals with disabilities, fostering a meaningful bond between the rider and horse...
January 12, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38240508/surviving-sepsis-campaign-research-priorities-2023
#40
JOURNAL ARTICLE
Daniel De Backer, Clifford S Deutschman, Judith Hellman, Sheila Nainan Myatra, Marlies Ostermann, Hallie C Prescott, Daniel Talmor, Massimo Antonelli, Luciano Cesar Pontes Azevedo, Seth R Bauer, Niranjan Kissoon, Ignacio-Martin Loeches, Mark Nunnally, Pierre Tissieres, Antoine Vieillard-Baron, Craig M Coopersmith
OBJECTIVES: To identify research priorities in the management, epidemiology, outcome, and pathophysiology of sepsis and septic shock. DESIGN: Shortly after publication of the most recent Surviving Sepsis Campaign Guidelines, the Surviving Sepsis Research Committee, a multiprofessional group of 16 international experts representing the European Society of Intensive Care Medicine and the Society of Critical Care Medicine, convened virtually and iteratively developed the article and recommendations, which represents an update from the 2018 Surviving Sepsis Campaign Research Priorities...
February 1, 2024: Critical Care Medicine
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