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Animal assisted therapy

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https://www.readbyqxmd.com/read/27895150/effects-of-va-facility-dog-on-hospitalized-veterans-seen-by-a-palliative-care-psychologist-an-innovative-approach-to-impacting-stress-indicators
#1
Cheryl A Krause-Parello, Cari Levy, Elizabeth Holman, John E Kolassa
The United States is home to 23 million veterans. In many instances, veterans with serious illness who seek healthcare at the VA receive care from a palliative care service. Animal-assisted intervention (AAI) is gaining attention as a therapeutic stress reducing modality; however, its effects have not been well studied in veterans receiving palliative care in an acute care setting. A crossover repeated-measures study was conducted to examine the effects of an animal-assisted intervention (AAI) in the form of a therapy dog on stress indicators in 25 veterans on the palliative care service at the VA Eastern Colorado Healthcare System in Denver, CO...
November 28, 2016: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/27863605/perceptions-of-a-hospital-based-animal-assisted-intervention-program-an-exploratory-study
#2
Kathleen Abrahamson, Yun Cai, Elizabeth Richards, Krista Cline, Marguerite E O'Haire
Research has shown that there are multiple benefits of animal assisted interventions for patients. However, the impact of interaction with these animals in staff is understudied, particularly in the acute care setting, and is thus a novel contribution to the literature on human-animal interaction. The purpose of this qualitative pilot study was to contribute to the body of knowledge surrounding the experiences and perceptions of hospital staff who have participated in a hospital-based animal assisted intervention program...
November 2016: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/27810365/treatment-of-parkinson-s-disease-in-rats-by-nrf2-transfection-using-mri-guided-focused-ultrasound-delivery-of-nanomicrobubbles
#3
Ling Long, Xiaodong Cai, Ruomi Guo, Ping Wang, Lili Wu, Tinghui Yin, Siyuan Liao, Zhengqi Lu
Parkinson's disease (PD) is a very common neurological disorder. However, effective therapy is lacking. Although the blood-brain-barrier (BBB) protects the brain, it prevents the delivery of about 90% of drugs and nucleotides into the brain, thereby hindering the development of gene therapy for PD. Magnetic resonance imaging (MRI)-guided focused ultrasound delivery of microbubbles enhances the delivery of gene therapy vectors across the BBB and improves transfection efficiency. In the present study, we delivered nuclear factor E2-related factor 2 (Nrf2, NFE2L2) contained in nanomicrobubbles into the substantia nigra of PD rats by MRI-guided focused ultrasound, and we examined the effect of Nrf2 over-expression in this animal model of PD...
October 31, 2016: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27754874/resolution-of-alliance-ruptures-the-special-case-of-animal-assisted-psychotherapy
#4
Sigal Zilcha-Mano
Many therapists regard alliance ruptures as one of the greatest challenges therapists face in the therapy room. Alliance ruptures has been previously defined as breakdowns in the process of negotiation of treatment tasks and goals and a deterioration in the affective bond between patient and therapist. Alliance ruptures have been found to predict premature termination of treatment and poor treatment outcomes. But ruptures can also present important opportunities for gaining insight and awareness and for facilitating therapeutic change...
October 17, 2016: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/27746677/more-than-just-a-break-from-treatment-how-substance-use-disorder-patients-experience-the-stable-environment-in-horse-assisted-therapy
#5
Ann Kern-Godal, Ida Halvorsen Brenna, Espen Ajo Arnevik, Edle Ravndal
Inclusion of horse-assisted therapy (HAT) in substance use disorder (SUD) treatment is rarely reported. Our previous studies show improved treatment retention and the importance of the patient-horse relationship. This qualitative study used thematic analysis, within a social constructionist framework, to explore how eight patients experienced contextual aspects of HAT's contribution to their SUD treatment. Participants described HAT as a "break from usual treatment". However, four interrelated aspects of this experience, namely "change of focus", "activity", "identity", and "motivation," suggest HAT is more than just a break from usual SUD treatment...
2016: Substance Abuse: Research and Treatment
https://www.readbyqxmd.com/read/27742758/animal-assisted-psychotherapy-a-unique-relational-therapy-for-children-and-adolescents
#6
Keren Bachi, Nancy Parish-Plass
No abstract text is available yet for this article.
October 14, 2016: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/27742757/animal-assisted-dyadic-therapy-a-therapy-model-promoting-development-of-the-reflective-function-in-the-parent-child-bond
#7
Liat Shani
Animal-assisted psychotherapy (AAP) inherently incorporates standpoints, interventions, and ways of action promoting the development of the reflective function and mentalization, and thus has special value for parent-child psychotherapy. Two central tools in AAP contribute to this process. The first is the ethical stance of the therapist, who sees the animals as full partners in the therapy situation, respecting them as subjects with needs, desires, and thoughts of their own. The second tool combines nonverbal communication with animals together with the relating, in the here and now, to the understanding and decoding of body language of everyone in the setting...
October 14, 2016: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/27711929/life-experiences-of-caring-for-pets-among-taiwanese-community-dwelling-older-adults-pets-as-an-integral-part-of-the-family-and-beyond
#8
Chia-Ling Yang, Chun-Ming Lee, Lee-Ing Tsao
The purpose of the current study was to use grounded theory to explore the experiences of caring for pets from the perspective of Taiwanese community-dwelling older adults. Twelve participants ages 65 to 73 were interviewed. Data were analyzed using the constant comparative method of qualitative analysis. Pets as an integral part of the family unit and beyond was the core category. The pet becomes part of my family was identified as the antecedent condition; this process undertakes action and interaction among the categories of the pet is part of my daily life, the pet provides positive life energy, and the pet is a sweet companion...
October 5, 2016: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/27703351/treatment-of-natural-mammary-gland-tumors-in-canines-and-felines-using-gold-nanorods-assisted-plasmonic-photothermal-therapy-to-induce-tumor-apoptosis
#9
Moustafa R K Ali, Ibrahim M Ibrahim, Hala R Ali, Salah A Selim, Mostafa A El-Sayed
Plasmonic photothermal therapy (PPTT) is a cancer therapy in which gold nanorods are injected at the site of a tumor before near-infrared light is transiently applied to the tumor causing localized cell death. Previously, PPTT studies have been carried out on xenograft mice models. Herein, we report a study showing the feasibility of PPTT as applied to natural tumors in the mammary glands of dogs and cats, which more realistically represent their human equivalents at the molecular level. We optimized a regime of three low PPTT doses at 2-week intervals that ablated tumors mainly via apoptosis in 13 natural mammary gland tumors from seven animals...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27667178/improvement-of-vascular-function-by-magnetic-nanoparticle-assisted-circumferential-gene-transfer-into-the-native-endothelium
#10
Sarah Vosen, Sarah Rieck, Alexandra Heidsieck, Olga Mykhaylyk, Katrin Zimmermann, Christian Plank, Bernhard Gleich, Alexander Pfeifer, Bernd K Fleischmann, Daniela Wenzel
Gene therapy is a promising approach for chronic disorders that require continuous treatment such as cardiovascular disease. Overexpression of vasoprotective genes has generated encouraging results in animal models, but not in clinical trials. One major problem in humans is the delivery of sufficient amounts of genetic vectors to the endothelium which is impeded by blood flow, whereas prolonged stop-flow conditions impose the risk of ischemia. In the current study we have therefore developed a strategy for the efficient circumferential lentiviral gene transfer in the native endothelium under constant flow conditions...
November 10, 2016: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/27629487/treatment-of-otitis-media-by-transtympanic-delivery-of-antibiotics
#11
Rong Yang, Vishakha Sabharwal, Obiajulu S Okonkwo, Nadya Shlykova, Rong Tong, Lily Yun Lin, Weiping Wang, Shutao Guo, John J Rosowski, Stephen I Pelton, Daniel S Kohane
Otitis media is the most common reason U.S. children receive antibiotics. The requisite 7- to 10-day course of oral antibiotics can be challenging to deliver in children, entails potential systemic toxicity, and encourages selection of antimicrobial-resistant bacteria. We developed a drug delivery system that, when applied once to the tympanic membrane through the external auditory canal, delivers an entire course of antimicrobial therapy to the middle ear. A pentablock copolymer poloxamer 407-polybutylphosphoester (P407-PBP) was designed to flow easily during application and then to form a mechanically strong hydrogel on the tympanic membrane...
September 14, 2016: Science Translational Medicine
https://www.readbyqxmd.com/read/27622163/spondylodiscitis-and-bacteremia-due-to-staphylococcus-hyicus-in-an-immunocompetent-man
#12
Maud Foissac, Maria Lekaditi, Bouchra Loutfi, Agnès Ehrhart, Frédéric-Antoine Dauchy
INTRODUCTION: Staphylococcus hyicus is a coagulase-variable Staphylococcus spp. well-known by veterinarians since it is the major agent of a severe cutaneous infection in piglets called exudative epidermitis. In other species the symptoms of infection are quite different. Human cases are uncommon but seem to occur more frequently after repeated contacts with farm animals. CASE REPORT: We report the case of a 58-year-old man suffering from debilitating subacute lumbar pain, in whom diagnosis of infectious spondylodiscitis was based on spine MRI and positive microbiological results...
September 2016: Germs
https://www.readbyqxmd.com/read/27616320/interactive-bio-feedback-therapy-using-hybrid-assistive-limbs-for-motor-recovery-after-stroke-current-practice-and-future-perspectives
#13
Takashi Morishita, Tooru Inoue
Interactive bio-feedback (iBF) was initially developed for the rehabilitation of motor function in patients with neurological disorders, and subsequently yielded the development of the hybrid assistive limb (HAL). Here, we provide a review of the theory underlying HAL treatment as well as our clinical experience and recommendations for future clinical studies using HAL in acute stroke patients. We performed a PubMed-based literature search, a retrospective data review of our acute stroke case series, and included a sample case report of our findings...
October 15, 2016: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/27609634/online-cardiac-output-estimation-during-transvalvular-left-ventricular-assistance
#14
Daniel Rüschen, Miriam Rimke, Jonas Gesenhues, Steffen Leonhardt, Marian Walter
BACKGROUND AND OBJECTIVES: Sufficient cardiac output is one of the main goals of ventricular assist device therapy. To date, there is no adequate method to estimate the combined amount of blood the native heart and a continuous-flow assist device pump through the circulatory system. This paper presents an approach to estimate total cardiac output based on the signals provided by optical pressure sensors mounted on the inlet and outlet of an Abiomed Impella CP pump. METHODS: Two Kalman filters were used in parallel for joint estimation of the aortic flow rate and the hydraulic resistance of the aortic valve...
August 30, 2016: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/27588200/conditions-for-the-generation-of-cytotoxic-cd4-th-cells-that-enhance-cd8-ctl-mediated-tumor-regression
#15
Kunyu Li, Margaret Baird, Jianping Yang, Chris Jackson, Franca Ronchese, Sarah Young
Adoptive cell therapies (ACTs) using tumor-reactive T cells have shown clinical benefit and potential for cancer treatment. While the majority of the current ACT are focused on using CD8(+) cytotoxic T lymphocytes (CTL), others have shown that the presence of tumor-reactive CD4(+) T helper (Th) cells can greatly enhance the anti-tumor activity of CD8(+) CTL. However, difficulties in obtaining adequate numbers of CD4(+) Th cells through in vitro expansion can limit the application of CD4 Th cells in ACT. This study aims to optimize the culture conditions for mouse CD4 T cells to provide basic information for animal studies of ACT using CD4 T cells...
August 2016: Clinical & Translational Immunology
https://www.readbyqxmd.com/read/27565411/metabotropic-glutamate-receptor-2-3-density-and-its-relation-to-the-hippocampal-neuropathology-in-a-model-of-temporal-lobe-epilepsy-in-rats
#16
Idrish Ali, Stephanie Boets, Pieter Janssens, Annemie Van Eetveldt, Halima Amhaoul, Xavier Langlois, Stefanie Dedeurwaerdere
Dysregulation in the glutamatergic function is considered a major contributor to hyperexcitatory neuronal networks in mesial temporal lobe epilepsy (MTLE). Studies in animal models of MTLE have shown positive outcomes of augmenting group 2-metabotropic receptor functions that can regulate neuronal excitability from extrasynaptic locations. To assist in efficient translation of these findings to the clinical settings, we aimed to characterise the expression of mGluR2/3 receptors in the brain areas relevant to MTLE...
August 13, 2016: Epilepsy Research
https://www.readbyqxmd.com/read/27555554/innovative-strength-based-care-in-child-and-adolescent-inpatient-psychiatry
#17
Deanna P Sams, David Garrison, Joanne Bartlett
PROBLEM: Child and adolescent psychiatric units serve the highest risk, most vulnerable populations in the mental health delivery system. This article describes the integration of a strength-based approach with a traditional, medical model of psychiatric care on an acute inpatient unit. A strength-based framework allows for increased focus on exploring patients' goals, strengths, relationships, skills, and family communication within the hospital setting. METHODS: The process of integration of strength-based care is described, followed by discussion of the implementation and evaluation of interventions, including mindfulness, family movie, narrative, and animal-assisted therapies...
August 2016: Journal of Child and Adolescent Psychiatric Nursing
https://www.readbyqxmd.com/read/27541053/using-animal-assisted-therapy-to-enrich-psychotherapy
#18
Jeanne Louise Amerine, Grace B Hubbard
Animal-assisted therapy (AAT) has been shown to be effective in the treatment of many psychological disorders, including autism spectrum disorders, depression, anxiety, and posttraumatic stress disorder (PTSD). AAT can be used as an adjunct to other forms of psychotherapy. With AAT, the animal becomes a part of the treatment plan. Outcomes for clients that are associated with the use of AAT include (1) increased sense of comfort and safety, (2) increased motivation, (3) enhanced self-esteem, (4) increased prosocial behaviors, and (5) decreased behavioral problems...
2016: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/27497015/animal-assisted-therapy-in-pediatric-palliative-care
#19
REVIEW
Mary Jo Gilmer, Marissa N Baudino, Anna Tielsch Goddard, Donna C Vickers, Terrah Foster Akard
Animal-assisted therapy is an emerging complementary strategy with an increasing presence in the literature. Limited studies have been conducted with children, particularly those with life-threatening and life-limiting conditions. Although outcomes show promise in decreasing suffering of children receiving palliative care services, more work is needed to validate evidence to support implementation of animal-assisted therapy with this vulnerable population.
September 2016: Nursing Clinics of North America
https://www.readbyqxmd.com/read/27469358/what-we-observe-in-vivo-is-not-always-what-we-see-in-vitro-development-and-validation-of-11c-jnj-42491293-a-novel-radioligand-for-mglur2
#20
Gil Leurquin-Sterk, Sofie Celen, Koen Van Laere, Michel Koole, Guy M Bormans, Xavier Langlois, Anne Van Hecken, Paula Te Riele, Jesús Alcázar, Alfons Verbruggen, Jan de Hoon, Jose-Ignacio Andrés, Mark E Schmidt
: Positive allosteric modulators (PAM) of metabotropic glutamate receptor 2 (mGluR2) are a potential novel therapy for anxiety, schizophrenia and addiction. Aside from pathophysiological imaging studies, an mGluR2 positron emission tomography (PET) tracer would enable confirmation of sufficient central target engagement and assist dose selection for proof of concept studies of PAM compounds. (11)C-JNJ-42491293, a novel high-affinity radioligand (hIC50 = 9.6 nM) for the PAM site of mGluR2, was evaluated as selective mGluR2 PAM PET tracer...
July 28, 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
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