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https://www.readbyqxmd.com/read/28234815/predicting-complications-in-immediate-alloplastic-breast-reconstruction-how-useful-is-the-american-college-of-surgeons-national-surgical-quality-improvement-program-surgical-risk-calculator
#1
Anne C O'Neill, Blake Murphy, Shaghayegh Bagher, Saad Al Qahtani, Stefan O P Hofer, Toni Zhong
BACKGROUND: Complications following immediate breast reconstruction can have significant consequences for the delivery of postoperative chemotherapy and radiation therapy. Identifying patients at higher risk of complications would ensure that immediate breast reconstruction does not compromise oncologic treatment. The American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator is an online tool in the public domain that offers individualized preoperative risk prediction for a wide range of surgical procedures, including alloplastic breast reconstruction...
March 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28232990/tunable-nanoelectromechanical-resonator-for-logic-computations
#2
Syed N R Kazmi, Md A A Hafiz, Karumbaiah N Chappanda, Saad Ilyas, Jorge Holguin, Pedro M F J Costa, Mohammad I Younis
There has been remarkable interest in nanomechanical computing elements that can potentially lead to a new era in computation due to their re-configurability, high integration density, and high switching speed. Here we present a nanomechanical device capable of dynamically performing logic operations (NOR, NOT, XNOR, XOR, and AND). The concept is based on the active tuning of the resonance frequency of a doubly-clamped nanoelectromechanical beam resonator through electro-thermal actuation. The performance of this re-configurable logic device is examined at elevated temperatures, ranging from 25 °C to 85 °C, demonstrating its resilience for most of the logic operations...
February 24, 2017: Nanoscale
https://www.readbyqxmd.com/read/28232252/the-effectiveness-of-three-weekly-injections-compared-to-five-weekly-injections-of-intra-articular-sodium-hyaluronate-on-pain-relief-of-knee-osteoarthritis-or-three-weekly-injections-of-other-hyaluronan-products-a-systematic-review-and-meta-analysis
#3
REVIEW
Todd P Stitik, Sony M Issac, Simple Modi, Saad Nasir, Irina Kulinets
OBJECTIVE: To investigate whether the number of hyaluronic acid (HA) injections in a Hyalgan(®) course of therapy alters effectiveness in reducing knee osteoarthritis (OA) pain. DATA SOURCES: Electronic databases, including PubMed and EMBase, were searched from January 1980 until November 2015. STUDY SELECTION: We included clinical studies that evaluated the effectiveness of a course of three or five weekly intra-articular injections of Hyalgan to treat knee OA pain...
February 20, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28230816/new-route-synthesis-of-thiadiazoles-bisthiadiazoles-thiadiazolotriazines-and-pyrazolothiadiazoles-based-on-hydrazonoyl-halides-and-dihydrazinylthiadiazole
#4
Abdelwahed R Sayed, Shar Saad Al-Shihry
Synthesis and characterization of new thiadiazoles, bisthiadiazoles from the reaction of mono- and di-hydrazonoyl halides with various hydrazinecarbodithioate derivatives were studied. Treatment of hydrazonoyl halides with 2,5-dihydrazinyl-1,3,4-thiadiazole afforded new bistriazines containing thiadiazole; we also examined the reaction of 2,5-dihydrazinyl-1,3,4-thiadiazole with active methylene compounds to afford new pyrazoles containing thiadiazole compounds. The new synthesized compounds were identified by elemental analysis and various spectral data (Fourier transform infrared spectroscopy, mass spectrometry, 1H and 13C nuclear magnetic resonance)...
February 21, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28230596/the-efficacy-of-immediate-implant-placement-in-extraction-sockets-for-alveolar-bone-preservation-a-clinical-evaluation-using-three-dimensional-cone-beam-computerized-tomography-and-resonance-frequency-analysis-value
#5
Ali Al Qabbani, Noor Hayati A Razak, Sausan Al Kawas, Suzina Sheikh Abdul Hamid, Saad Wahbi, A R Samsudin
The aim of this study was to determine the efficacy of immediate implant placement with alveolar bone augmentation on socket preservation following atraumatic tooth extraction and comparing it with a tooth alveolar socket that was allowed to heal in a conventional way.Twenty medically fit patients (8 males and 12 females aged between 18 and 40 years) who needed noncomplicated tooth extraction of mandibular premolar teeth were divided randomly and equally into 2 groups. In Group I, the empty extraction socket was left untreated and allowed to heal in a conventional way...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28229483/venous-hemodialysis-catheters-and-cardiac-implantable-electronic-devices-avoiding-a-high-risk-combination
#6
EDITORIAL
Theodore F Saad, Henry L Weiner
End-stage renal disease is frequently accompanied by cardiac comorbidity that warrants treatment with a cardiovascular implantable electronic device (permanent pacemaker or implantable cardioverter-defibrillator). In the United States, chronic hemodialysis (HD) population, cardiac implantable devices are present in up to 10.5% of patients; a venous HD catheter is utilized for blood access in 18% of prevalent patients. The concomitant presence of a venous HD catheter and cardiovascular implantable device creates a high-risk circumstance, with potential for causing symptomatic central venous stenosis, and for developing complicated endovascular infection...
February 23, 2017: Seminars in Dialysis
https://www.readbyqxmd.com/read/28229231/hair-follicle-changes-following-intense-pulsed-light-axillary-hair-reduction-histometrical-histological-and-immunohistochemical-evaluation
#7
Moetaz El-Domyati, Wael Hosam, Noha H Moftah, Hamza Abdel Raouf, Selwet M Saad
Intense pulsed light (IPL) has been used for years in hair reduction; however, no previous studies discussed quantitative histological and immunohistochemical changes of hair follicles after IPL. Accordingly, this study aims to objectively quantify histological and immunohistochemical changes of hair follicles after IPL hair reduction. Right axillae of 21 volunteers were subjected to 6 IPL sessions using Quanta system IPL and evaluated at 1 week and 1 month after last session (i.e., 3 and 4 months from the start of treatment, respectively) in comparison to baseline and left control axillae...
February 22, 2017: Archives of Dermatological Research
https://www.readbyqxmd.com/read/28228971/exfoliation-of-graphene-sheets-via-high-energy-wet-milling-of-graphite-in-2-ethylhexanol-and-kerosene
#8
Al-Sayed Al-Sherbini, Mona Bakr, Iman Ghoneim, Mohamed Saad
Graphene sheets have been exfoliated from bulk graphite using high energy wet milling in two different solvents that were 2-ethylhexanol and kerosene. The milling process was performed for 60 h using a planetary ball mill. Morphological characteristics were investigated using scanning electron microscope (SEM) and transmission electron microscope (TEM). On the other hand, the structural characterization was performed using X-ray diffraction technique (XRD) and Raman spectrometry. The exfoliated graphene sheets have represented good morphological and structural characteristics with a valuable amount of defects and a good graphitic structure...
May 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28228528/clinical-genetic-and-structural-basis-of-congenital-adrenal-hyperplasia-due-to-11%C3%AE-hydroxylase-deficiency
#9
Ahmed Khattab, Shozeb Haider, Ameet Kumar, Samarth Dhawan, Dauood Alam, Raquel Romero, James Burns, Di Li, Jessica Estatico, Simran Rahi, Saleel Fatima, Ali Alzahrani, Mona Hafez, Noha Musa, Maryam Razzghy Azar, Najoua Khaloul, Moez Gribaa, Ali Saad, Ilhem Ben Charfeddine, Berenice Bilharinho de Mendonça, Alicia Belgorosky, Katja Dumic, Miroslav Dumic, Javier Aisenberg, Nurgun Kandemir, Ayfer Alikasifoglu, Alev Ozon, Nazli Gonc, Tina Cheng, Ursula Kuhnle-Krahl, Marco Cappa, Paul-Martin Holterhus, Munier A Nour, Daniele Pacaud, Assaf Holtzman, Sun Li, Mone Zaidi, Tony Yuen, Maria I New
Congenital adrenal hyperplasia (CAH), resulting from mutations in CYP11B1, a gene encoding 11β-hydroxylase, represents a rare autosomal recessive Mendelian disorder of aberrant sex steroid production. Unlike CAH caused by 21-hydroxylase deficiency, the disease is far more common in the Middle East and North Africa, where consanguinity is common often resulting in identical mutations. Clinically, affected female newborns are profoundly virilized (Prader score of 4/5), and both genders display significantly advanced bone ages and are oftentimes hypertensive...
February 22, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28227413/segmentation-of-the-metacarpus-and-phalange-in-musculoskeletal-ultrasound-images-using-local-active-contours
#10
Nelson Martins, Malik Saad Sultan, Diana Veiga, Manuel Ferreira, Miguel Coimbra, Nelson Martins, Malik Saad Sultan, Diana Veiga, Manuel Ferreira, Miguel Coimbra, Diana Veiga, Nelson Martins, Malik Saad Sultan, Miguel Coimbra, Manuel Ferreira
This work presents a method for the automatic segmentation of metacarpus and phalange bones in ultrasound images of the second metacarpophalangeal joint (MCPJ) using Active Contours. The MCPJ is known to be the one of the first structures to be affected by rheumatic diseases like rheumatoid arthritis. The early detection and follow-up of this disease is important to prevent irreversible damage of the joints, which occurs continuously and faster if no treatment is used. To our knowledge, there is no automatic system to quantify the extension of the lesions resulting from rheumatic activity...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226685/tracking-of-the-anterior-mitral-leaflet-in-echocardiographic-sequences-using-active-contours
#11
Malik Saad Sultan, Nelson Martins, Diana Veiga, Manuel Joao Ferreira, Miguel Tavares Coimbra, Malik Saad Sultan, Nelson Martins, Diana Veiga, Manuel Joao Ferreira, Miguel Tavares Coimbra, Diana Veiga, Nelson Martins, Malik Saad Sultan, Miguel Tavares Coimbra, Manuel Joao Ferreira
Echocardiography assessment of cardiac valves plays a vital role in the diagnosis of rheumatic heart disease. In the vast majority of cases, the mitral valve gets affected, leading to the thickening of its leaflets that may result in the fusion of their tips. This changes the appearance and reduces the mobility of the leaflets, which also reduce the heart efficiency. Quantifying such parameters provides diagnostic insight. To achieve that, the first step is to identify and then track fast moving leaflets. This work is focused on Anterior Mitral Leaflet (AML) tracking...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226004/guillain-barr%C3%A3-syndrome-and-other-neurological-manifestations-possibly-related-to-zika-virus-infection-in-municipalities-from-bahia-brazil-2015
#12
Juliane Maria Alves Siqueira Malta, Alexander Vargas, Priscila Leal E Leite, Jadher Percio, Giovanini Evelim Coelho, Andréa Helena Argolo Ferraro, Tânia Maria de Oliveira Cordeiro, Jesângeli de Sousa Dias, Eduardo Saad
Objective: to describe the reported cases of Guillain-Barré Syndrome (GBS) and other neurological manifestations with a history of dengue, chikungunya or Zika virus infections, in the Metropolitan Region of Salvador and in the municipality of Feira de Santana, Brazil. Methods: this is a descriptive study with data of an investigation conducted by the epidemiological surveillance from March to August 2015; to confirm the neurological manifestations, medical diagnosis records were considered, and to prior infection, clinical and laboratory criteria were used...
January 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/28225809/the-renal-consequences-of-maternal-obesity-in-offspring-are-overwhelmed-by-postnatal-high-fat-diet
#13
Sarah J Glastras, Hui Chen, Michael Tsang, Rachel Teh, Rachel T McGrath, Amgad Zaky, Jason Chen, Muh Geot Wong, Carol A Pollock, Sonia Saad
AIMS/HYPOTHESIS: Developmental programming induced by maternal obesity influences the development of chronic disease in offspring. In the present study, we aimed to determine whether maternal obesity exaggerates obesity-related kidney disease. METHODS: Female C57BL/6 mice were fed high-fat diet (HFD) for six weeks prior to mating, during gestation and lactation. Male offspring were weaned to normal chow or HFD. At postnatal Week 8, HFD-fed offspring were administered one dose streptozotocin (STZ, 100 mg/kg i...
2017: PloS One
https://www.readbyqxmd.com/read/28225558/cutaneous-adnexal-adenocarcinoma-with-exquisite-sensitivity-to-trastuzumab
#14
Timothy J Brown, David J Sher, Lucien A Nedzi, Randall S Hughes, Muhammad S Beg, Jason Mull, Venetia R Sarode, Saad A Khan
BACKGROUND: Cutaneous adnexal adenocarcinoma is a rare cancer that is occasionally human epidermal growth factor receptor-2 (HER-2)-positive, and demonstrates variable response to HER-2 inhibitors. METHODS: We report a case of adnexal adenocarcinoma of the scalp in a 56-year-old man. He underwent wide local excision with cervical node dissection followed by radiation, but had extensive local recurrence. RESULTS: Pathology demonstrated a poorly differentiated adnexal adenocarcinoma with HER-2 overexpression by immunohistochemistry (IHC) and high HER-2 gene amplification by fluorescence in situ hybridization...
February 22, 2017: Head & Neck
https://www.readbyqxmd.com/read/28224289/two-different-techniques-for-frontalis-suspension-using-gore-tex-to-treat-severe-congenital-ptosis
#15
Adel Galal Zaky, Sameh Saad Mandour, Marwa Aly Zaky, Asmaa Mohamed Ebrahem
PURPOSE: Severe congenital ptosis is commonly associated with poor levator function. This study compares the functional and cosmetic outcomes of open versus closed frontalis sling using Gore-Tex in the treatment of such conditions. METHODS: Randomized interventional comparative case series of 20 eyes of 13 patients with severe congenital ptosis with levator excursion < 4 mm. Patients were treated by frontalis suspension using Gore-Tex string sutures either through a skin crease incision (group 1) or supraciliary incisions (group II)...
February 21, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28220546/novel-splice-site-mutation-in-eif2ak3-gene-causes-wolcott-rallison-syndrome-in-a-consanguineous-family-from-saudi-arabia
#16
Jumana Yousuf Al-Aama, Hams Saeed Al-Zahrani, Musharraf Jelani, Hesham Salih Sabir, Saad Abdullah Al-Saeedi, Saleem Ahmed
No abstract text is available yet for this article.
February 21, 2017: Congenital Anomalies
https://www.readbyqxmd.com/read/28219945/novel-fixed-z-dimension-fizd-kidney-primordia-and-an-organoid-culture-system-for-time-lapse-confocal-imaging
#17
Ulla Saarela, Saad Ullah Akram, Audrey Desgrange, Aleksandra Rak-Raszewska, Jingdong Shan, Silvia Cereghini, Veli-Pekka Ronkainen, Janne Heikkilä, Ilya Skovorodkin, Seppo J Vainio
Tissue, organ and organoid cultures provide suitable models for developmental studies, but our understanding of how the organs are assembled at the single cell level still remains unclear. We describe here a novel Fixed Z-Dimension (FiZD) culture setup that permits high-resolution confocal imaging of organoids and embryonic tissues. In a FiZD culture a permeable membrane compresses the tissues onto a glass coverslip and the spacers adjust the thickness, enabling the tissue to grow for up to 12 days. Thus the kidney rudiment and the organoids can adjust to the limited Z-dimensional space and yet advance the process of kidney morphogenesis, enabling long-term time-lapse and high-resolution confocal imaging...
February 20, 2017: Development
https://www.readbyqxmd.com/read/28219264/we-are-not-gametes-distinguishing-between-abortion-and-contraception
#18
Toni Saad
It is sometimes argued that interruptions of the life's continuum which have the same end result are morally equivalent. In other words, abortion and contraception are ethically identical because both prevent birth and the development of persons. We will examine two major arguments in favour of this thesis: (1) all things that are potential persons have equal moral status. Hence preventing fertilisation of gametes is morally identical to destroying an embryo; (2) all interruptions of the continuous process which leads to the creation of a person are morally equivalent; abortion and contraception are morally indistinguishable...
November 2016: New Bioethics: a Multidisciplinary Journal of Biotechnology and the Body
https://www.readbyqxmd.com/read/28218537/siderophore-and-organic-acid-promoted-dissolution-and-transformation-of-cr-iii-fe-iii-oxy-hydroxides
#19
Emily M Saad, Jingying Sun, Shuo Chen, Olaf J Borkiewicz, Mengqiang Zhu, Owen W Duckworth, Yuanzhi Tang
The role of microbial activities on the transformation of chromium (Cr) remediation products has generally been overlooked. This study investigated the stability of Cr(III)-Fe(III)-(oxy)hydroxides, common Cr(VI) remediation products, with a range of compositions in the presence of common microbial exudates, siderophores and small organic acids. In the presence of a representative siderophore, desferrioxamine B (DFOB), iron (Fe) was released at higher rates and to greater extents relative to Cr from all solid phases...
February 20, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28217052/topical-versus-caudal-ketamine-bupivacaine-combination-for-postoperative-analgesia-in-children-undergoing-inguinal-herniotomy
#20
Hala Saad Abdel-Ghaffar, Seham Mohamed Moeen, Ahmed Mohamed Moeen
BACKGROUND: Multiple studies claim that caudal administration of ketamine causes effective postoperative analgesia. The aim of this study was to assess the clinical effectiveness of ketamine after caudal or topical administration in pediatric patients undergoing inguinal herniotomy. PATIENTS AND METHODS: This randomized, comparative, double-blind study included eighty children (aged 6 months to 6 years) received either 1 ml/kg of 0.25% bupivacaine/ketamine 0.5 mg/kg for caudal analgesia (caudal group) or 0...
January 2017: Saudi Journal of Anaesthesia
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