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JOURNAL ARTICLE
Sheri L Balsara, Danielle Burstein, Richard F Ittenbach, Michelle Kaplinski, Monique M Gardner, Chitra Ravishankar, Joseph Rossano, David J Goldberg, Marlene Mahle, Matthew J O'Connor, Christopher E Mascio, J William Gaynor, Tamar J Preminger
BACKGROUND: Infants with hypoplastic left heart syndrome (HLHS) or a variant are at risk of ventricular dysfunction (VD) and atrioventricular valve regurgitation (AVVR) prior to superior cavopulmonary connection (SCPC). Although the impact of these complications in isolation has been described, their effect in combination on attrition is poorly defined. METHODS: A retrospective observational study of patients with HLHS or variants undergoing a Norwood procedure between 2008 and 2020 at a single center was performed...
December 2023: JTCVS open
#22
JOURNAL ARTICLE
Zachary N Blalock, Gwyneth W Y Wu, Daniel Lindqvist, Caroline Trumpff, Janine D Flory, Jue Lin, Victor I Reus, Ryan Rampersaud, Rasha Hammamieh, Aarti Gautam, Francis J Doyle, Charles R Marmar, Marti Jett, Rachel Yehuda, Owen M Wolkowitz, Synthia H Mellon
Circulating cell-free mitochondrial DNA (ccf-mtDNA) is a biomarker of cellular injury or cellular stress and is a potential novel biomarker of psychological stress and of various brain, somatic, and psychiatric disorders. No studies have yet analyzed ccf-mtDNA levels in post-traumatic stress disorder (PTSD), despite evidence of mitochondrial dysfunction in this condition. In the current study, we compared plasma ccf-mtDNA levels in combat trauma-exposed male veterans with PTSD (n = 111) with those who did not develop PTSD (n = 121) and also investigated the relationship between ccf mt-DNA levels and glucocorticoid sensitivity...
January 10, 2024: Translational Psychiatry
#23
JOURNAL ARTICLE
Danielle R Eugene, Cristin Blalock, Juterh Nmah, Philip Baiden
Previous research has identified mental health symptoms such as depression and aggression as contributing factors associated with suicidal ideation and attempts in adolescence. However, much of this work has focused on older adolescents (ages > 14) resulting in a dearth of knowledge about early adolescents under 12 years. Moreover, much less is known about school connectedness as a protective factor in the relationship between mental health symptoms and suicidal behaviors. This study examined the interaction effect between school connectedness and mental health symptoms on suicidal behaviors among early adolescents aged 9-12 years...
June 2023: School Mental Health
#24
JOURNAL ARTICLE
Jamie L Manwaring, Dan V Blalock, Alan Duffy, Daniel Le Grange, Philip S Mehler, Megan Riddle, Renee D Rienecke
OBJECTIVE: Anorexia nervosa (AN) is a serious illness with a high mortality rate and multiple physiological complications. The vague definition of atypical AN allows for subjective interpretation. This retrospective study aimed to focus future research on the operational definition of atypical AN by examining four factors associated with atypical AN at admission to higher level of care treatment. METHODS: Adults with atypical AN (n = 69) were examined within sample analyses among four groups: (1) >10% versus ≤10% weight loss; (2) weight loss within the previous 3 months versus >3 months; (3) engaging in purging behaviors versus absence of purging behaviors; and (4) endorsing versus not endorsing significant cognitive aspects of AN...
January 2, 2024: International Journal of Eating Disorders
#25
JOURNAL ARTICLE
Hamood N Al Kindi, Shamsa Al Kaabi, Hasina Al Harthi, Thuraya Al Harthi, Ahmed Al Habsi, Pranav Kandachar
OBJECTIVES: The size of the pulmonary valve annulus often determines the feasibility of pulmonary valve preservation at the time of intracardiac repair of Tetralogy of Fallot. Currently, there is limited available data regarding the growth pattern and the determining factors that contribute towards pulmonary valve annulus growth. METHODS: This retrospective study included patients who underwent surgical repair of Tetralogy of Fallot with or without prior palliation...
December 2023: Sultan Qaboos University Medical Journal
#26
JOURNAL ARTICLE
Blalock-Taussig Shunt versus Ductal Stenting as Palliation for Duct-Dependent Pulmonary Circulation.
Hamood Al Kindi, Hasina Al Harthi, Asim Al Balushi, Ahlam Atiq, Samiuddin Shaikh, Khalid Al Alawi, Abdullah Al-Farqani
OBJECTIVES: There is limited data published from outside North America and Europe comparing the outcomes of a modified Blalock-Taussig shunt (MBTS) and ductal stenting as the first palliative procedure for infants with duct-dependent pulmonary circulation. This study reports the National Heart Center's, in Muscat, Oman, experience in comparing the outcomes of these 2 interventions. METHODS: This retrospective study included all infants with duct-dependent pulmonary circulation who received either a MBTS or ductal stenting from 2016-2019...
December 2023: Sultan Qaboos University Medical Journal
#27
JOURNAL ARTICLE
Dilek Dilli, Hasan Akduman, Ayşegül Zenciroğlu, Merih Çetinkaya, Nilüfer Okur, Özden Turan, Ferda Özlü, Şebnem Çalkavur, Gamze Demirel, Nilgün Koksal, Rüya Çolak, Utku Arman Örün, Erkut Öztürk, Özlem Gül, Niyazi Kürşad Tokel, Sevcan Erdem, Timur Meşe, Abdullah Erdem, Özlem Mehtap Bostan, Tuğçin Bora Polat, Mehmet Taşar, Ali Can Hatemi, Onur Doyurgan, Murat Özkan, Mustafa Kemal Avşar, Osman Nejat Sarıosmanoğlu, Murat Uğurlucan, Işık Şenkaya Sığnak, Murat Başaran
Critical congenital heart disease (CCHD) is one of the leading causes of neonatal and infant mortality. We aimed to elucidate the epidemiology, spectrum, and outcome of neonatal CCHD in Türkiye. This was a multicenter epidemiological study of neonates with CCHD conducted from October 2021 to November 2022 at national tertiary health centers. Data from 488 neonatal CCHD patients from nine centers were entered into the Trials-Network online registry system during the study period. Transposition of great arteria was the most common neonatal CHD, accounting for 19...
December 28, 2023: Pediatric Cardiology
#28
JOURNAL ARTICLE
Joseph A Dodson, Sarah A Ibrahim, Howard Rogers, M Laurin Council, Kishwer S Nehal, Rebecca Tung, David J Leffell, Nathalie C Zeitouni, Mariam B Totonchy, Scott W Fosko, Seaver Lee Soon, Travis W Blalock, David G Brodland, Elizabeth M Billingsley, Jeffrey F Scott, Brian C Leach, Desiree Ratner, Carl Washington, C William Hanke, Clark C Otley, Nicholas Golda, Rajiv I Nijhawan, Jerry Brewer, Addison Demer, Frederick Fish, Christopher B Harmon, John Zitelli, Thomas Knackstedt, Gaurav Singh, Todd Mollet, David R Carr, John G Albertini, Brent R Moody, Michel McDonald, Jeremy S Bordeaux, Paul R Massey, Mollie A MacCormack, Allison Vidimos, Christopher J Arpey, Sarah T Arron, Omar A Ibrahimi, S Brian Jiang, Christopher J Miller, Ian A Maher, Ashley Wysong, Barry Leshin, Glenn D Goldman, Nour Kibbi, Hao Feng, Lindsey Collins
BACKGROUND: Amid a movement toward value-based healthcare, increasing emphasis has been placed on outcomes and cost of medical services. To define and demonstrate the quality of services provided by Mohs surgeons, it is important to identify and understand the key aspects of Mohs micrographic surgery (MMS) that contribute to excellence in patient care. OBJECTIVE: The purpose of this study is to develop and identify a comprehensive list of metrics in an initial effort to define excellence in MMS...
December 9, 2023: Journal of the American Academy of Dermatology
#29
JOURNAL ARTICLE
Maryrose Bauschka, Ashlie Watters, Dan Blalock, Asma Farooq, Philip Mehler, Dennis Gibson
BACKGROUND: There are no U.S. Food and Drug Administration (FDA)-approved medications for the treatment of anorexia nervosa (AN). Various medication classes have been evaluated for benefits in this population, including antipsychotics. Studies focused on use of antipsychotics for assistance with weight restoration in AN produced conflicting results. While current evidence does not suggest that antipsychotic medications can be generally recommended for persons with AN, some individuals might benefit from an antipsychotic medication for anxiety, mood, and the cognitive distortions that accompany the illness...
December 6, 2023: Journal of Eating Disorders
#30
JOURNAL ARTICLE
Renee D Rienecke, Dan V Blalock, Haley D Mills, Alan Duffy, Jamie Manwaring, Daniel Le Grange, Philip S Mehler, Susan McClanahan, Maryrose Bauschka, Craig Johnson
The current study assessed treatment outcome for 99 adult admissions to a residential program specifically designed for binge eating spectrum disorders (BESD). Participants completed self-report measures at admission, discharge, and 12-month follow-up and were asked to complete blood draws at admission and follow-up. Primary outcomes were eating behaviors; secondary outcomes included comorbid symptoms and physiological variables. Eating behaviors improved significantly from admission to follow-up, as did most comorbid symptoms and quality of life, despite no change in body mass index...
December 4, 2023: Eating Disorders
#31
JOURNAL ARTICLE
Diwen Li, Tianli Zhao, Shijun Hu, Weizhi Zhang, Zhongshi Wu, Jijia Liu
OBJECTIVES: For patients with tetralogy of Fallot (TOF) who are not suitable candidates for primary corrective surgery or have a high surgical risk, transcatheter right ventricular outflow tract (RVOT) stent implantation is considered a safe and effective palliative intervention. This study aims to investigate the therapeutic outcomes of RVOT stent implantation in neonates and infants with TOF in comparison with the modified Blalock-Taussig shunt (mBTS) and to compare the impact of the 2 palliative interventions on arterial oxygen saturation and pulmonary artery development in pediatric patients...
2023: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
#32
JOURNAL ARTICLE
Bethan A Lemley, Lezhou Wu, Amy L Roberts, Russell T Shinohara, William O Quarshie, Athar M Qureshi, Christopher L Smith, Yoav Dori, Matthew J Gillespie, Jonathan J Rome, Andrew C Glatz, Sandra Amaral, Michael L O'Byrne
BACKGROUND: The modified Blalock-Taussig-Thomas shunt is the gold standard palliation for securing pulmonary blood flow in infants with ductal-dependent pulmonary blood flow. Recently, the ductus arteriosus stent (DAS) has become a viable alternative. METHODS AND RESULTS: This was a retrospective multicenter study of neonates ≤30 days undergoing DAS or Blalock-Taussig-Thomas shunt placement between January 1, 2017 and December 31, 2020 at hospitals reporting to the Pediatric Health Information Systems database...
December 1, 2023: Journal of the American Heart Association
#33
Jonathan C Vincent, Colleen N Garnett, James B Watson, Emma K Higgins, Teresa Macheda, Lydia Sanders, Kelly N Roberts, Ryan K Shahidehpour, Eric M Blalock, Ning Quan, Adam D Bachstetter
No abstract text is available yet for this article.
November 30, 2023: Journal of Neuroinflammation
#34
JOURNAL ARTICLE
Putri Amelia, Najib Advani, Aman B Pulungan, Mulyadi M Djer, Badriul Hegar, Yogi Prawira, Rubiana Sukardi
BACKGROUND: Blalock-Taussig (BT) is a palliative procedure that preserves blood circulation to the lungs and alleviates cyanosis in patients with congenital heart diseases and reduced pulmonary blood flow. BT shunt remains a routinely performed procedure in developing countries before definitive surgery. However, evidence on predictor factors of mortality after this procedure is still scarce in Indonesia. This study evaluated the predictive factors of mortality after the BT shunt procedure...
2023: International Journal of General Medicine
#35
JOURNAL ARTICLE
Humera Ahmed, Jeffrey B Anderson, Katherine E Bates, Carole M Lannon, David W Brown
BACKGROUND: Derived from the National Pediatric Cardiology Quality Improvement Collaborative registry, the NEONATE risk score predicted freedom from interstage mortality or heart transplant for patients with single ventricle CHD and aortic arch hypoplasia discharged home following Stage 1 palliation. OBJECTIVES: We sought to validate the score in an external, modern cohort. METHODS: This was a retrospective cohort analysis of single ventricle CHD and aortic arch hypoplasia patients enrolled in the National Pediatric Cardiology Quality Improvement Collaborative Phase II registry from 2016 to 2020, who were discharged home after Stage 1 palliation...
November 28, 2023: Cardiology in the Young
#36
JOURNAL ARTICLE
Renee D Rienecke, Philip S Mehler, Alan Duffy, Daniel Le Grange, Dan V Blalock
OBJECTIVE: Although eating disorders (EDs) occur throughout the lifespan, little research has been conducted with midlife/older adults, particularly those in higher levels of care (HLOC). The current study examined outcomes among 2009 patients with EDs receiving HLOC treatment at a large multisite facility between January 2020 and June 2022, across different age groups (ages <18, 18-25, 26-39 and ≥40). It was hypothesised that patients aged 40+ would exhibit less improvement on measures of ED psychopathology and depression than other age groups...
November 27, 2023: European Eating Disorders Review: the Journal of the Eating Disorders Association
#37
Stasa Krasic, Ivan Dizdarevic, Lana Vranic, Dejan Nešić, Vladislav Vukomanovic
Clinical presentation, course, and treatment for patients with isolated right ventricular (RV) hypoplasia (IRVH) depends on the degree of hypoplasia that is present-this is a spectrum from spontaneous maturation to Fontan circulation over time. An 8-month-old infant presented with IRVH; in the patient, a modified Blalock-Taussig (MBTS) shunt was closed percutaneously after spontaneous RV function recovery. A female newborn was diagnosed with differential cyanosis at birth. The echocardiography showed a hypertrophic RV with a small cavity, a right-left shunt on the atrial septal defect, an almost closed ductus arteriosus (DA), and a small tricuspid valve ring (Z-score-2) with mild regurgitation (pressure gradient 30 mmHg)...
November 15, 2023: Journal of Cardiovascular Development and Disease
#38
JOURNAL ARTICLE
Elisa Schena, Elisabetta Mattioli, Chiara Peres, Laura Zanotti, Paolo Morselli, Patricia Iozzo, Maria Angela Guzzardi, Chiara Bernardini, Monica Forni, Salvatore Nesci, Massimiliano Caprio, Carolina Cecchetti, Uberto Pagotto, Elena Gabusi, Luca Cattini, Gina Lisignoli, William Blalock, Alessandra Gambineri, Giovanna Lattanzi
Type-2 Familial Partial Lipodystrophy (FPLD2), a rare lipodystrophy caused by LMNA mutations, is characterized by a loss of subcutaneous fat from the trunk and limbs and excess accumulation of adipose tissue in the neck and face. Several studies have reported that the mineralocorticoid receptor (MR) plays an essential role in adipose tissue differentiation and functionality. We previously showed that brown preadipocytes isolated from a FPLD2 patient's neck aberrantly differentiate towards the white lineage...
November 7, 2023: Cells
#39
JOURNAL ARTICLE
Erin E Reilly, Sasha Gorrell, Craig Johnson, Alan Duffy, Dan V Blalock, Philip Mehler, Madelyn Johnson, Daniel Le Grange, Renee D Rienecke
OBJECTIVE: Smartphone applications (i.e., apps) designed to target mental health symptoms have received increasing public and empirical attention, including in eating disorder|eating disorders (EDs) treatment. While some data have begun to characterise app users in non-controlled settings, there is limited information on use of apps in higher levels of care (e.g., partial hospitalisation or residential treatment programs) for EDs. METHOD: This study aimed to explore metrics of use while in treatment for a commonly used ED-focused mobile app (Recovery Record) among individuals enroled in intensive outpatient, partial hospitalisation, residential, or inpatient treatments (N = 2042)...
November 23, 2023: European Eating Disorders Review: the Journal of the Eating Disorders Association
#40
JOURNAL ARTICLE
Diego B Ortega-Zhindón, Nonanzit Pérez-Hernández, José Manuel Rodríguez-Pérez, José A García-Montes, Juan Calderón-Colmenero, Frida Rivera-Buendía, Jorge L Cervantes-Salazar
Right atrial isomerism (RAI) is a complex entity with varying diagnostic and treatment outcomes due to its rarity. Treatment options range from palliative to corrective surgeries, resulting in heterogeneous outcomes. The aim of this study was to analyze the results obtained after cardiac surgery in patients with RAI. A retrospective study was conducted, including patients diagnosed with RAI who underwent cardiac surgery. Their follow-up was from 1 January 2010 to 31 March 2020. Demographic characteristics and perioperative conditions were described...
November 20, 2023: Diseases (Basel)
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