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https://www.readbyqxmd.com/read/28421915/use-of-a-modified-classic-bt-shunt-in-a-patient-with-multiple-conduit-obstructions-with-positive-lupus-anticoagulant
#1
Pallav Bhattarai, Ayesha Zia, Joseph M Forbess, Kristine J Guleserian, Susan R Hupp, Timothy Pirolli
The use of a right ventricle-to-pulmonary artery conduit has re-emerged as a popular alternative to a systemic artery-to-pulmonary artery shunt in the Norwood procedure. Both proximal obstruction secondary to dynamic compression and distal obstruction at the anastomosis site with the pulmonary arteries are well described. In an effort to prevent complications, a technique where in the conduit is placed through the entire full thickness, or dunked, through the RV free wall has been described. We report a case of a patient with HLHS and positive lupus anticoagulant who developed recurrent conduit obstructions...
January 1, 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28412153/the-effect-of-counseling-on-willingness-to-use-a-hypothetical-medication-and-perceptions-of-medication-safety
#2
Michael Bitonti, Payal Patel, Rebecca Dickinson, Peter Knapp, Susan J Blalock
BACKGROUND: Poor medication adherence is an ongoing issue, and contributes to increased hospitalizations and healthcare costs. Although most adverse effects are rare, the perceived risk of adverse effects may contribute to low adherence rates. OBJECTIVES: The objective of this study was to determine how adverse effect likelihood and pharmacist counseling on adverse effect prevention affects individuals': (1) willingness to use a hypothetical medication and (2) perceptions of medication safety...
March 31, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28393796/modified-blalock-taussig-shunt-and-levosimendan-for-left-ventricular-preparation-in-a-child-with-transposition-of-great-arteries-and-regressed-ventricle-undergoing-rapid-2-stage-arterial-switch-operation
#3
Manoj Kumar Sahu, Anish Gupta, Intekhab Alam, Sarvesh Pal Singh, Ramesh Menon, V Devagouru
Rapid two-stage arterial switch operation (ASO) is very relevant as many patients of transposition of great arteries (TGA) present late to the hospital when primary switch either is not possible or carries a high risk of morbidity and mortality. Hence, other means apart from the traditional methods of left ventricle preparedness should be tried to help this category of patients, who are to undergo rapid two-stage ASO. We successfully used levosimendan and continuous positive airway pressure after 1st stage operation in a patient with dTGA and regressed ventricle, which helped in left ventricular preparedness, and the child underwent rapid two-stage ASO uneventfully...
April 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28383929/personality-strengths-in-romantic-relationships-measuring-perceptions-of-benefits-and-costs-and-their-impact-on-personal-and-relational-well-being
#4
Todd B Kashdan, Dan V Blalock, Kevin C Young, Kyla A Machell, Samuel S Monfort, Patrick E McKnight, Patty Ferssizidis
Three studies using samples of people in romantic relationships were conducted to create a new individual difference measure of partner strengths in couples. The 2 perceptions of partner strengths included (1) appreciation of their use and effectiveness and (2) recognition of costs associated with their use. Factor analyses supported 2-factors and we found that greater appreciation of partner strengths predicted greater relationship satisfaction, commitment, investment, intimacy, self-expansion, and support for goal pursuit; recognizing significant costs with partner strengths was inversely related to several outcomes...
April 6, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28382440/tetralogy-of-fallot-surgical-repair-shunt-configurations-ductus-arteriosus-and-the-circle-of-willis
#5
Senol Piskin, Gozde Unal, Ahmet Arnaz, Tayyar Sarioglu, Kerem Pekkan
In this study, hemodynamic performance of three novel shunt configurations that are considered for the surgical repair of tetralogy of Fallot (TOF) disease are investigated in detail. Clinical experience suggests that the shunt location, connecting angle, and its diameter can influence the post-operative physiology and the neurodevelopment of the neonatal patient. An experimentally validated second order computational fluid dynamics (CFD) solver and a parametric neonatal diseased great artery model that incorporates the ductus arteriosus (DA) and the full patient-specific circle of Willis (CoW) are employed...
April 5, 2017: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/28381428/doxycycline-improves-clinical-outcomes-during-cystic-fibrosis-exacerbations
#6
Xin Xu, Tarek Abdalla, Preston E Bratcher, Patricia L Jackson, Gina Sabbatini, J Michael Wells, Xiang-Yang Lou, Rebecca Quinn, J Edwin Blalock, J P Clancy, Amit Gaggar
Matrix metalloprotease-9 (MMP-9) plays a role in progression of cystic fibrosis, and doxycycline can reduce MMP-9 in vitro Here, we explore the effect of doxycycline during cystic fibrosis exacerbation treatment on MMP-9 related readouts and clinical end-points.This randomised, double-blind, placebo-controlled study enrolled hospitalised patients with cystic fibrosis undergoing exacerbation. In total, 20 participants were given doxycycline and 19 participants were given placebo over an 8-day period during hospitalisation...
April 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28380701/falls-risks-and-prevention-behaviors-among-community-dwelling-homebound-and-non-homebound-older-adults
#7
Carri Casteel, Jennifer Jones, Paula Gildner, James M Bowling, Susan J Blalock
The objectives were to examine falls risk factors to determine how the magnitude of risk may differ between homebound and non-homebound older adults, and to describe falls prevention behaviors and participation in falls prevention education. A cross-sectional survey was conducted with convenience samples of community-dwelling older adults recruited through Meals on Wheels programs (homebound, n = 80) and senior centers (non-homebound, n = 84) in North Carolina. Data were collected during home visits and included an interview and medication inventory...
October 1, 2016: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/28380592/effects-of-the-interaction-of-forage-and-supplement-type-on-digestibility-and-ruminal-fermentation-in-beef-cattle
#8
M R Stierwalt, H M Blalock, T L Felix
The objectives of this research were to test interactions of supplement type, liquid versus dry, and forage type, hay versus corn stover, on digestibility and ruminal metabolism of beef cattle. Ruminally fistulated steers were fed in a replicated 4 × 4 Latin square with a 2 × 2 factorial arrangement of treatments: 1) hay with liquid supplement, 2) hay with dry supplement, 3) corn stover with liquid supplement, and 4) corn stover with dry supplement. The liquid supplement was molasses and glycerin based (23...
February 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28365601/productivity-of-senior-dental-students-engaged-in-comprehensive-care-a-seven-year-follow-up-study
#9
John S Blalock, Richard S Callan, Anthony G Mollica
The aims of this study were to determine the trend of senior dental students' rate of production of clinical procedures performed in the comprehensive care clinic at one U.S. dental school and to compare that trend to what was reported immediately following inception of that clinic. In addition, total clinic revenues collected were recorded and compared. The periods used for comparisons were 2005 and 2006 combined, the last years before introduction of comprehensive care (called "pre-comp care"); 2007 and 2008 combined, the first two years of comprehensive care (called "post-comp care"); and subsequent years through 2014...
April 2017: Journal of Dental Education
https://www.readbyqxmd.com/read/28303931/the-development-of-novel-lta4h-modulators-to-selectively-target-ltb4-generation
#10
Caroline M Low, Samia Akthar, Dhiren F Patel, Stephan Löser, Chi-Tung Wong, Patricia L Jackson, J Edwin Blalock, Stephen A Hare, Clare M Lloyd, Robert J Snelgrove
The pro-inflammatory mediator leukotriene B4 (LTB4) is implicated in the pathologies of an array of diseases and thus represents an attractive therapeutic target. The enzyme leukotriene A4 hydrolase (LTA4H) catalyses the distal step in LTB4 synthesis and hence inhibitors of this enzyme have been actively pursued. Despite potent LTA4H inhibitors entering clinical trials all have failed to show efficacy. We recently identified a secondary anti-inflammatory role for LTA4H in degrading the neutrophil chemoattractant Pro-Gly-Pro (PGP) and rationalized that the failure of conventional LTA4H inhibitors may be that they inadvertently prevented PGP degradation...
March 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28300528/functional-near-tricuspid-atresia-in-a-patient-with-absent-pulmonary-valve-and-an-intact-ventricular-septum
#11
Yasunobu Miki, Toshikatsu Tanaka, Yoshihiro Oshima
Absent pulmonary valve with an intact ventricular septum is a rare malformation. We report a case of absent pulmonary valve and intact ventricular septum with functional near-tricuspid atresia caused by pulmonary regurgitation. Initial palliation with main pulmonary artery ligation and bilateral pulmonary artery banding was performed at 1 day of age. More antegrade flow across the tricuspid valve was recognised postoperatively, resulting in a successful right ventricular outflow tract reconstruction by a hand-sewn bileaflet polytetrafluoroethylene valve and modified Blalock-Taussig shunt at 11 days of age...
March 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28281413/percutaneous-closure-of-multiple-ventricular-septal-defects-simultaneous-use-of-muscular-ventricular-septal-defect-device-and-multi-fenestrated-septal-occluder-cribriform-to-close-residual-ventricular-septal-defects-after-complex-cardiac-surgery-in-a-child
#12
Shreesha S Maiya, Smruti V Patel, Chinnaswamy Reddy, Suresh V Pujar
A male child, with d-transposition of great arteries, a large perimembranous ventricular septal defect, multiple additional ventricular septal defects, small muscle-bound right ventricle, and severe pulmonary stenosis with confluent, moderate-sized branch pulmonary arteries, underwent an emergency right modified Blalock-Taussig shunt on day 15 of life and réparation à l'étageventriculaire procedure with ventricular septal defect closure with takedown of the Blalock-Taussig shunt at 2.5 years of age. On follow-up, he showed a moderate residual upper ventricular septal defect and multiple apical ventricular septal defects, mild mid-right pulmonary artery stenosis, free pulmonary regurgitation, and right ventricular dysfunction...
January 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28274521/cavopulmonary-anastomosis-during-same-hospitalization-as-stage-1-norwood-hybrid-palliative-surgery
#13
Sachin D Tadphale, Xinyu Tang, Nahed O ElHassan, Brandon Beam, Parthak Prodhan
BACKGROUND: Limited literature has examined characteristics of infants with hypoplastic left heart syndrome (HLHS) who remain hospitalized during the interstage period. We described their epidemiologic characteristics, in-hospital outcomes, and identified risk factors that predict the need for superior cavopulmonary anastomosis (SCPA) during the same hospitalization. METHODS: This retrospective multicenter database analysis included infants with HLHS who underwent stage 1 palliation from 2004 through 2013...
March 5, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28268644/tunable-somatosensory-stimulation-for-selective-sleep-restriction-studies-in-rodents
#14
Dillon M Huffman, Kendra E Staggs, Farid Yaghouby, Anuj Agarwal, Bruce F O'Hara, Kevin D Donohue, Eric M Blalock, Sridhar Sunderam
Many methods for sleep restriction in rodents have emerged, but most are intrusive, lack fine control, and induce stress. Therefore, a versatile, non-intrusive means of sleep restriction that can alter sleep in a controlled manner could be of great value in sleep research. In previous work, we proposed a novel system for closed-loop somatosensory stimulation based on mechanical vibration and applied it to the task of restricting Rapid Eye Movement (REM) sleep in mice [1]. While this system was effective, it was a crude prototype and did not allow precise control over the amplitude and frequency of stimulation applied to the animal...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226824/tunable-somatosensory-stimulation-for-selective-sleep-restriction-studies-in-rodents
#15
Dillon M Huffman, Kendra E Staggs, Farid Yaghouby, Anuj Agarwal, Bruce F O'Hara, Kevin D Donohue, Eric M Blalock, Sridhar Sunderam, Dillon M Huffman, Kendra E Staggs, Farid Yaghouby, Anuj Agarwal, Bruce F O'Hara, Kevin D Donohue, Eric M Blalock, Sridhar Sunderam, Eric M Blalock, Bruce F O'Hara, Kevin D Donohue, Kendra E Staggs, Sridhar Sunderam, Anuj Agarwal, Dillon M Huffman, Farid Yaghouby
Many methods for sleep restriction in rodents have emerged, but most are intrusive, lack fine control, and induce stress. Therefore, a versatile, non-intrusive means of sleep restriction that can alter sleep in a controlled manner could be of great value in sleep research. In previous work, we proposed a novel system for closed-loop somatosensory stimulation based on mechanical vibration and applied it to the task of restricting Rapid Eye Movement (REM) sleep in mice [1]. While this system was effective, it was a crude prototype and did not allow precise control over the amplitude and frequency of stimulation applied to the animal...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28164248/medication-risk-communication-in-rheumatology-where-are-we-and-where-do-we-go-from-here
#16
REVIEW
Susan J Blalock
This paper reviews findings from recent research examining issues related to the risk communication process within the context of rheumatologic conditions. Five specific questions are addressed. First, to what extent do patients with rheumatic disorders exhibit adequate knowledge relevant to disease and medication risks and risk management? Second, what sources do patients use when attempting to find information about disease and medication risks and risk management? Third, what types of information about disease and medication risks and risk management do rheumatologists provide during routine office visits...
February 2017: Current Rheumatology Reports
https://www.readbyqxmd.com/read/28163422/transcatheter-pulmonary-valve-perforation-using-chronic-total-occlusion-wire-in-pulmonary-atresia-with-intact-ventricular-septum
#17
Shweta Bakhru, Shilpa Marathe, Manish Saxena, Sudeep Verma, Rajan Saileela, Tapan K Dash, Nageswara Rao Koneti
BACKGROUND: Perforation of pulmonary valve using radiofrequency ablation in pulmonary atresia with intact ventricular septum (PA IVS) is a treatment of choice. However, significant cost of the equipment limits its utility, especially in the developing economies. OBJECTIVE: To assess the feasibility, safety, and efficacy of perforation of pulmonary valve using chronic total occlusion (CTO) wires in patients with PA IVS as an alternative to radiofrequency ablation...
January 2017: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/28154913/right-ventricle-to-pulmonary-artery-shunt-in-pulmonary-atresia-with-a-ventricular-septal-defect-a-word-of-caution
#18
Kwang Ho Choi, Si Chan Sung, Hyungtae Kim, Hyoung Doo Lee, Gil Ho Ban, Geena Kim, Hoon Ko
The management of pulmonary atresia with a ventricular septal defect (PA/VSD) depends on the anatomy of the pulmonary artery or on the surgical strategy used at individual institutions. In our institution, we adopted a right ventricle-to-pulmonary artery (RV-PA) shunt in 2011 as a palliative procedure for PA/VSD to overcome the disadvantages of a Blalock-Taussig shunt. We evaluated the results of the RV-PA shunt as initial palliative surgery for PA/VSD. Thirteen patients with ductus-dependent PA/VSD from August 2011 to August 2015 were enrolled...
February 3, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28146206/case-1-2017-percutaneous-repair-of-right-atrioventricular-valve-insufficiency-and-blalock-taussig-shunt-after-fontan-operation-in-single-ventricle
#19
Edmar Atik, Renata Sá Cassar, Raul Arrieta
No abstract text is available yet for this article.
January 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28118786/mathematical-analysis-and-physical-profile-of-blalock-taussig-shunt-and-sano-modification-procedure-in-hypoplastic-left-heart-syndrome
#20
Efrain Riveros Perez, Ricardo Riveros
The first stage of surgical treatment for hypoplastic left heart syndrome (HLHS) includes the creation of artificial systemic-to-pulmonary connections to provide pulmonary blood flow. The modified Blalock-Taussig (mBT) shunt has been the technique of choice for this procedure; however, a right ventricle-pulmonary artery (RV-PA) shunt has been introduced into clinical practice with encouraging but still conflicting outcomes when compared with the mBT shunt. The aim of this study is to explore mathematical modeling as a tool for describing physical profiles that could assist the surgical team in predicting complications related to stenosis and malfunction of grafts in an attempt to find correlations with clinical outcomes from clinical studies that compared both surgical techniques and to assist the anesthesiologist in making decisions to manage patients with this complex cardiac anatomy...
January 1, 2017: Seminars in Cardiothoracic and Vascular Anesthesia
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