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https://www.readbyqxmd.com/read/29455404/the-effect-of-pre-surgery-information-online-lecture-on-nutrition-knowledge-and-anxiety-among-bariatric-surgery-candidates
#1
Shiri Sherf-Dagan, Keren Hod, Limor Mardy-Tilbor, Shir Gliksman, Tair Ben-Porat, Nasser Sakran, Shira Zelber-Sagi, David Goitein, Asnat Raziel
INTRODUCTION: Best practices for patient education in bariatric surgery (BS) remain undefined. The aims of this study were to evaluate the effect of an online lecture on nutrition knowledge, weight loss expectations, and anxiety among BS candidates and present a new tool to assess this knowledge before BS. METHODS: An interventional non-randomized controlled trial on 200 BS candidates recruited while attending a pre-BS committee. The first 100 consecutive patients were assigned to the control group and the latter 100 consecutive patients to the intervention group and were instructed to watch an online lecture of 15-min 1-2 weeks prior to surgery...
February 17, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29432156/role-of-ubiquitylation-of-components-of-mitotic-checkpoint-complex-in-their-dissociation-from-anaphase-promoting-complex-cyclosome
#2
Danielle Sitry-Shevah, Sharon Kaisari, Adar Teichner, Shirly Miniowitz-Shemtov, Avram Hershko
The mitotic checkpoint system ensures the fidelity of chromosome segregation in mitosis by preventing premature initiation of anaphase until correct bipolar attachment of chromosomes to the mitotic spindle is reached. It promotes the assembly of a mitotic checkpoint complex (MCC), composed of BubR1, Bub3, Cdc20, and Mad2, which inhibits the activity of the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. When the checkpoint is satisfied, anaphase is initiated by the disassembly of MCC. Previous studies indicated that the dissociation of APC/C-bound MCC requires ubiquitylation and suggested that the target of ubiquitylation is the Cdc20 component of MCC...
February 5, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29431759/structural-dynamics-upon-photoexcitation-induced-charge-transfer-in-a-dicopper-i-disulfide-complex
#3
Maria Naumova, Dmitry Khakhulin, Mateusz Rebarz, Martin Rohrmüller, Benjamin Dicke, Mykola Biednov, Alexander Britz, Shirly Espinoza, Benjamin Grimm-Lebsanft, Miroslav Kloz, Norman Kretzschmar, Adam Neuba, Jochen Ortmeyer, Roland Schoch, Jakob Andreasson, Matthias Bauer, Christian Bressler, Wolf Gero Schmidt, Gerald Henkel, Michael Rübhausen
The structural dynamics of charge-transfer states of nitrogen-ligated copper complexes has been extensively investigated in recent years following the development of pump-probe X-ray techniques. In this study we extend this approach towards copper complexes with sulfur coordination and investigate the influence of charge transfer states on the structure of a dicopper(i) complex with coordination by bridging disulfide ligands and additionally tetramethylguanidine units [CuI2(NSSN)2]2+. In order to directly observe and refine the photoinduced structural changes in the solvated complex we applied picosecond pump-probe X-ray absorption spectroscopy (XAS) and wide-angle X-ray scattering (WAXS)...
February 12, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29426647/relationship-between-root-apices-and-the-mandibular-canal-a-cone-beam-computed-tomographic-comparison-of-3-populations
#4
Alex Lvovsky, Shir Bachrach, Hyeon-Cheol Kim, Ajinkya Pawar, Oleg Levinzon, Joe Ben Itzhak, Michael Solomonov
INTRODUCTION: This study aimed to investigate the difference in the location of the inferior alveolar nerve (IAN) in relation to the apices of mandibular molars in 3 different populations using cone-beam computed tomographic (CBCT) imaging and to assess the proportion of teeth in close proximity (a distance of 1 mm or less) to the IAN. METHODS: Random CBCT images (N = 1224, Israel = 408, South Korea = 416, and India = 400) were examined. The shortest distance to the mandibular canal was measured by imaging software...
February 6, 2018: Journal of Endodontics
https://www.readbyqxmd.com/read/29423724/superficial-acral-fibromyxoma-a-case-report-with-radiological-review
#5
Shirly Lee, Michael Austin Ross Reid
Superficial acral fibromyxoma is a benign, slow-growing soft-tissue neoplasm that has a predilection for the peripheries. Although considered benign, its risk of recurrence warrants consideration in the radiological differential diagnoses of acral tumors. To our knowledge, there has been minimal literature studying the radiological features of this entity. We present a case report with a discussion focusing on its clinical and radiological findings.
February 8, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29420930/better-than-optimal
#6
Shir Shalom, Adam Zaidel
Using a novel visual-tactile paradigm in rats, Nikbakht et al. (2018) describe multisensory behavior that outperformed predictions of optimal cue combination (indicating cross-modal synergy) and exposed encoding in PPC neurons (of stimulus and choice signals) that was independent of stimulus modality.
February 7, 2018: Neuron
https://www.readbyqxmd.com/read/29415030/religiosity-prevalence-and-its-association-with-depression-and-anxiety-symptoms-among-hispanic-latino-adults
#7
Shir Lerman, Molly Jung, Elva M Arredondo, Janice M Barnhart, Jianwen Cai, Sheila F Castañeda, Martha L Daviglus, Rebeca A Espinoza, Aida L Giachello, Kristine M Molina, Krista Perreira, Hugo Salgado, Sylvia Wassertheil-Smoller, Robert C Kaplan
OBJECTIVES: Religion plays an important role in the lives of people in the United States. We examined the prevalence of religiosity among Hispanic/Latinos in four regions of the United States and looked at its correlation to depression and anxiety symptoms. DESIGN: The population-based Hispanic Community Health Study/ Study of Latinos enrolled a cohort of Hispanic/Latino adults (N = 16,415) ages 18-74 in four US cities from June 2008 to June 2011. Participants with complete data on religiosity (i...
2018: PloS One
https://www.readbyqxmd.com/read/29403068/cpap3-proteins-in-the-mineralized-cuticle-of-a-decapod-crustacean
#8
Shai Abehsera, Shir Zaccai, Binyamin Mittelman, Lilah Glazer, Simy Weil, Isam Khalaila, Geula Davidov, Ronit Bitton, Raz Zarivach, Shihao Li, Fuhua Li, Jianhai Xiang, Rivka Manor, Eliahu D Aflalo, Amir Sagi
The pancrustacean theory groups crustaceans and hexapods (once thought to comprise separate clades within the Arthropoda) into a single clade. A key feature common to all pancrustaceans is their chitinous exoskeleton, with a major contribution by cuticular proteins. Among these, are the CPAP3's, a family of cuticular proteins, first identified in the hexapod Drosophila melanogaster and characterized by an N-terminal signaling peptide and three chitin-binding domains. In this study, CPAP3 proteins were mined from a transcriptomic library of a decapod crustacean, the crayfish Cherax quadricarinatus...
February 5, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29392213/diagnostic-confounders-of-chronic-widespread-pain-not-always-fibromyalgia
#9
REVIEW
Winfried Häuser, Serge Perrot, Claudia Sommer, Yoram Shir, Mary-Ann Fitzcharles
Introduction: Chronic widespread pain (CWP) is the defining feature of fibromyalgia (FM), a worldwide prevalent condition. Chronic widespread pain is, however, not pathognomonic of FM, and other conditions may present similarly with CWP, requiring consideration of a differential diagnosis. Objectives: To conduct a literature search to identify medical conditions that may mimic FM and have highlighted features that may differentiate these various conditions from FM...
May 2017: Pain Reports (Baltimore, Md.)
https://www.readbyqxmd.com/read/29356369/analysis-of-economic-and-environmental-aspects-of-microalgae-biorefinery-for-biofuels-production-a-review
#10
REVIEW
Shir Reen Chia, Kit Wayne Chew, Pau Loke Show, Yee Jiun Yap, Hwai Chyuan Ong, Tau Chuan Ling, Jo-Shu Chang
Microalgae are considered promising feedstock for the production of biofuels and other bioactive compounds, yet there are still challenges on commercial applications of microalgae-based products. This review focuses on the economic analysis, environmental impact and industrial potential of biofuels production from microalgae. The cost of biofuels production remains higher compared to conventional fuel sources. However, integration of biorefinery pathways with biofuels production for the recovery of value-added products (such as antioxidants, natural dyes, cosmetics, nutritional supplements, polyunsaturated fatty acids and so forth) could substantially reduce the production costs...
January 22, 2018: Biotechnology Journal
https://www.readbyqxmd.com/read/29351199/biofilm-forming-potential-of-staphylococcus-aureus-isolated-from-clinical-mastitis-cases-in-new-zealand
#11
Shirli Notcovich, Gina DeNicolo, Steve H Flint, Norman B Williamson, Kristene Gedye, Alex Grinberg, Nicolas Lopez-Villalobos
Biofilm formation is of growing concern in human and animal health. However, it is still unclear how biofilms are related to mastitis infections in dairy cattle. In this study, a comparison between two tests for biofilm formation and the association between biofilm and the presence of genes associated with biofilm formation were investigated for 92 Staphylococcus aureus isolates from clinical mastitis cases. Congo red agar (CRA) and microtitre test assay (MTA) in vitro phenotypic tests were used to evaluate biofilm formation...
January 19, 2018: Veterinary Sciences
https://www.readbyqxmd.com/read/29348360/complete-genome-sequences-of-three-moraxella-osloensis-strains-isolated-from-human-skin
#12
Jae Yun Lim, Ingyu Hwang, Munkhtsatsral Ganzorig, Shir-Ly Huang, Gyu-Sung Cho, Charles M A P Franz, Kyoung Lee
Here, we present the complete whole-genome sequences of three Moraxella osloensis strains with octylphenol polyethoxylate-degrading abilities. These strains were isolated from human skin.
January 18, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29345426/single-dose-intravenous-iron-in-southeast-asian-heart-failure-patients-a-pilot-randomized-placebo-controlled-study-practice-asia-hf
#13
Tee Joo Yeo, Poh Shuan Daniel Yeo, Farid Abdul Hadi, Timothy Cushway, Kim Yee Lee, Fang Fang Yin, Anne Ching, Ruili Li, Seet Yoong Loh, Shir Lynn Lim, Raymond Ching-Chiew Wong, Bee Choo Tai, Arthur Mark Richards, Carolyn S P Lam
AIMS: Iron deficiency is highly prevalent in Southeast Asians with heart failure (HF) and associated with worse outcomes. This trial aimed to assess the effect of intravenous iron in Southeast Asians hospitalized with decompensated HF. METHODS AND RESULTS: Fifty patients hospitalized for acute decompensated HF, regardless of ejection fraction, with iron deficiency (defined as serum ferritin <300 ng/mL if transferrin saturation is <20%) were randomized to receive either one dose of intravenous ferric carboxymaltose (FCM) 1000 mg or placebo (0...
January 18, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29326274/social-place-cells-in-the-bat-hippocampus
#14
David B Omer, Shir R Maimon, Liora Las, Nachum Ulanovsky
Social animals have to know the spatial positions of conspecifics. However, it is unknown how the position of others is represented in the brain. We designed a spatial observational-learning task, in which an observer bat mimicked a demonstrator bat while we recorded hippocampal dorsal-CA1 neurons from the observer bat. A neuronal subpopulation represented the position of the other bat, in allocentric coordinates. About half of these "social place-cells" represented also the observer's own position-that is, were place cells...
January 12, 2018: Science
https://www.readbyqxmd.com/read/29311649/high-content-image-analysis-reveals-function-of-mir-124-upstream-of-vimentin-in-regulating-motor-neuron-mitochondria
#15
Tal Yardeni, Raquel Fine, Yuvraj Joshi, Tal Gradus-Pery, Noga Kozer, Irit Reichenstein, Eran Yanowski, Shir Nevo, Hila Weiss-Tishler, Michal Eisenberg-Bord, Tal Shalit, Alexander Plotnikov, Haim M Barr, Eran Perlson, Eran Hornstein
microRNAs (miRNAs) are critical for neuronal function and their dysregulation is repeatedly observed in neurodegenerative diseases. Here, we implemented high content image analysis for investigating the impact of several miRNAs in mouse primary motor neurons. This survey directed our attention to the neuron-specific miR-124, which controls axonal morphology. By performing next generation sequencing analysis and molecular studies, we characterized novel roles for miR-124 in control of mitochondria localization and function...
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29283270/an-east-west-comparison-of-self-care-barriers-in-heart-failure
#16
Shir Lynn Lim, Siew Pang Chan, Kim Yee Lee, Anne Ching, Richard J Holden, Karen F Miller, Alan B Storrow, Carolyn Sp Lam, Sean P Collins
BACKGROUND: Barriers in heart failure self-care contribute to heart failure hospitalizations, but geographic differences have not been well-studied. We aimed to compare self-care barriers in heart failure patients managed at tertiary centers in an Eastern (Singapore) versus a Western (USA) nation. METHODS: Acute heart failure patients were prospectively assessed with a standardized instrument comprising of 47 distinct self-care barriers. The multi-equation generalized structural equation model was used to evaluate for geographic differences in barriers experienced, and association of barriers with outcomes...
December 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29279643/meckel-s-diverticulitis-masquerading-as-acute-pancreatitis-a-diagnostic-dilemma
#17
C Danny Darlington, G Fatima Shirly Anitha
Meckel's diverticulum is a remnant of the proximal part of the vitellointestinal duct and is the most common congenital anomaly of the gastrointestinal tract. It may either remain asymptomatic or present with myriad of clinical presentations. Gastrointestinal bleeding is the most common presentation in children whereas it is intestinal obstruction in the case of adults. We report a 9-year-old boy who presented with acute onset of periumbilical pain and nonbilious vomiting. His clinical and laboratory parameters were unremarkable, except for serum amylase levels...
November 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29237698/oxys-small-rna-induces-cell-cycle-arrest-to-allow-dna-damage-repair
#18
Shir Barshishat, Maya Elgrably-Weiss, Jonathan Edelstein, Jens Georg, Sutharsan Govindarajan, Meytal Haviv, Patrick R Wright, Wolfgang R Hess, Shoshy Altuvia
To maintain genome integrity, organisms employ DNA damage response, the underlying principles of which are conserved from bacteria to humans. The bacterial small RNA OxyS of Escherichia coli is induced upon oxidative stress and has been implicated in protecting cells from DNA damage; however, the mechanism by which OxyS confers genome stability remained unknown. Here, we revealed an OxyS-induced molecular checkpoint relay, leading to temporary cell cycle arrest to allow damage repair. By repressing the expression of the essential transcription termination factor nusG, OxyS enables read-through transcription into a cryptic prophage encoding kilR The KilR protein interferes with the function of the major cell division protein FtsZ, thus imposing growth arrest...
December 13, 2017: EMBO Journal
https://www.readbyqxmd.com/read/29229829/psma-targeted-polyinosine-polycytosine-vector-induces-prostate-tumor-regression-and-invokes-an-antitumor-immune-response-in-mice
#19
Yael Langut, Alaa Talhami, Samarasimhareddy Mamidi, Alexei Shir, Maya Zigler, Salim Joubran, Anna Sagalov, Efrat Flashner-Abramson, Nufar Edinger, Shoshana Klein, Alexander Levitzki
There is an urgent need for an effective treatment for metastatic prostate cancer (PC). Prostate tumors invariably overexpress prostate surface membrane antigen (PSMA). We designed a nonviral vector, PEI-PEG-DUPA (PPD), comprising polyethylenimine-polyethyleneglycol (PEI-PEG) tethered to the PSMA ligand, 2-[3-(1, 3-dicarboxy propyl)ureido] pentanedioic acid (DUPA), to treat PC. The purpose of PEI is to bind polyinosinic/polycytosinic acid (polyIC) and allow endosomal release, while DUPA targets PC cells. PolyIC activates multiple pathways that lead to tumor cell death and to the activation of bystander effects that harness the immune system against the tumor, attacking nontargeted neighboring tumor cells and reducing the probability of acquired resistance and disease recurrence...
December 26, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29166315/poly-implants-prosth%C3%A3-se-breast-implants-a-case-series-and-review-of-the-literature
#20
Doron Klein, Eran Hadad, Itay Wiser, Omer Wolf, Ortal Itzhaki Shapira, Shir Fucks, Lior Heller
BACKGROUND: Silicone breast implants from the French manufacturer Poly Implants Prosthèse (PIP) were recalled from the European market after the French regulator has revealed the implants contain non-medical-grade silicone filler. In December 2011, following a large increase in reported rupture rate and a possible cancer risk, the French Ministry of Health recommended consideration of the PIP explantation, regardless of their condition. In 2012, the Israel Ministry of Health recommended to replace the implants only upon suspected implant rupture...
January 2018: Annals of Plastic Surgery
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