keyword
MENU ▼
Read by QxMD icon Read
search

Shir

keyword
https://www.readbyqxmd.com/read/27919369/informing-the-development-of-an-internet-based-chronic-pain-self-management-program
#1
Amédé Gogovor, Regina Visca, Claudine Auger, Lucie Bouvrette-Leblanc, Iphigenia Symeonidis, Lise Poissant, Mark A Ware, Yoram Shir, Natacha Viens, Sara Ahmed
BACKGROUND: Self-management can optimize health outcomes for individuals with chronic pain (CP), an increasing fiscal and social burden in Canada. However, self-management is rarely integrated into the regular care (team activities and medical treatment) patients receive. Health information technology offers an opportunity to provide regular monitoring and exchange of information between patient and care team. OBJECTIVE: To identify information needs and gaps in chronic pain management as well as technology features to inform the development of an Internet-based self-management program...
January 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/27918636/4d-printing-of-shape-memory-based-personalized-endoluminal-medical-devices
#2
Matt Zarek, Nicola Mansour, Shir Shapira, Daniel Cohn
The convergence of additive manufacturing and shape-morphing materials is promising for the advancement of personalized medical devices. The capability to transform 3D objects from one shape to another, right off the print bed, is known as 4D printing. Shape memory thermosets can be tailored to have a range of thermomechanical properties favorable to medical devices, but processing them is a challenge because they are insoluble and do not flow at any temperature. This study presents here a strategy to capitalize on a series of medical imaging modalities to construct a printable shape memory endoluminal device, exemplified by a tracheal stent...
December 5, 2016: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/27858895/awareness-of-primary-spontaneous-hemorrhagic-angiosarcoma-of-the-breast-associated-with-kasabach-merritt-syndrome-in-a-pregnant-woman-by-enhanced-magnetic-resonance-imaging-a-care-compliant-case-report
#3
Wei-Ming Lin, Yu-Hsiang Juan, Yu-Ching Lin, Shir-Hwa Ueng, Yung-Feng Lo, Yun-Chung Cheung
INTRODUCTION: Primary breast angiosarcoma with spontaneous intratumoral bleeding associating with Kasabach-Merritt Syndrome is rarely reported. CASE FINDINGS/PATIENT CONCERNS: We herein present such a case in a 30-year-old pregnant woman who was initially diagnosed to hemangioma at her early gestation. However, the sudden rapid tumor growth was aware of the attention and intended for receiving the breast enhanced magnetic resonance imaging. DIAGNOSES AND INTERVENTIONS: The dynamic MRI enhancement showed inhomogenous enhancement at the periphery of the lobulated tumor on both early and delayed scans, otherwise a large hematoma was revealed at the center...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27856072/the-behind-the-scenes-activity-of-parental-decision-making-discourse-regarding-childhood-vaccination
#4
Anat Gesser-Edelsburg, Nathan Walter, Yaffa Shir-Raz, Oshrat Sassoni Bar-Lev, Shira Rosenblat
BACKGROUND: Vaccine compliance has long been a cause for concern for health authorities throughout the world. However very little effort has been made to examine parental discourse during the decision-making process. METHODS: An online survey was conducted (N = 437) to examine predictors of parents' attitudes regarding childhood vaccination. RESULTS: Hesitant parents were 4 times more likely to conduct intrafamily discussion regarding vaccination compared with provaccination parents (Exp[B] = 4...
November 14, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/27810925/cd72-negatively-regulates-b-lymphocyte-responses-to-the-lupus-related-endogenous-toll-like-receptor-7-ligand-sm-rnp
#5
Chizuru Akatsu, Kenro Shinagawa, Nobutaka Numoto, Zhihong Liu, Ayse Konuskan Ucar, Mohammad Aslam, Shirly Phoon, Takahiro Adachi, Koji Furukawa, Nobutoshi Ito, Takeshi Tsubata
Toll-like receptor 7 (TLR7) plays an essential role in development of systemic lupus erythematosus by co-stimulating B cells reactive to the endogenous TLR7 ligand Sm/ribonucleoprotein (RNP), a crucial lupus self-antigen. However, how the TLR7-mediated autoimmune response is regulated is not yet known. In this study, we demonstrate that CD72, an inhibitory B cell co-receptor known to prevent development of lupus, recognizes Sm/RNP at the extracellular C-type lectin-like domain (CTLD) and specifically inhibits B cell response to Sm/RNP...
November 14, 2016: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/27810359/the-testis-specific-usp26-is-a-deubiquitinating-enzyme-of-the-ubiquitin-ligase-mdm2
#6
Shirly Lahav-Baratz, Yelena Kravtsova-Ivantsiv, Shai Golan, Aaron Ciechanover
Murine double minute-2 (Mdm2) is one of the E3-ligases of the androgen receptor besides being the major regulator of the p53 tumor suppressor. The testis-specific USP26 was demonstrated to regulate the androgen receptor. In the present study we examined possible association between the deubiquitinating enzyme - ubiquitin specific protease 26 (USP26), and the oncoprotein E3 ligase - (Mdm-2). We analyzed the half-life time of USP26 in HEK293 cells. In a cell-free system we asked whether USP26 can be ubiquitinated by HeLa extract...
October 31, 2016: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27803347/dr-fitzcharles-et-al-reply
#7
Mary-Ann Fitzcharles, Peter A Ste-Marie, Emmanouil Rampakakis, John S Sampalis, Yoram Shir
No abstract text is available yet for this article.
November 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27766560/dynamics-of-flair-volume-changes-in-glioblastoma-and-prediction-of-survival
#8
Rachel Grossman, Nir Shimony, Dror Shir, Tal Gonen, Razi Sitt, Tali Jonas Kimchi, Carmit Ben Harosh, Zvi Ram
BACKGROUND: The extent of tumor resection (EOTR) calculated by enhanced T1 changes in glioblastomas has been previously reported to predict survival. However, fluid-attenuated inversion recovery (FLAIR) volume may better represent tumor burden. In this study, we report the first assessment of the dynamics of FLAIR volume changes over time as a predictive variable for post-resection overall survival (OS). METHODS: Contemporary data from 103 consecutive patients with complete imaging and clinical data who underwent resection of newly diagnosed glioblastoma followed by the Stupp protocol between 2010 and 2013 were analyzed...
October 20, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27741281/high-ancient-genetic-diversity-of-human-lice-pediculus-humanus-from-israel-reveals-new-insights-into-the-origin-of-clade-b-lice
#9
Nadia Amanzougaghene, Kosta Y Mumcuoglu, Florence Fenollar, Shir Alfi, Gonca Yesilyurt, Didier Raoult, Oleg Mediannikov
The human head louse, Pediculus humanus capitis, is subdivided into several significantly divergent mitochondrial haplogroups, each with particular geographical distributions. Historically, they are among the oldest human parasites, representing an excellent marker for tracking older events in human evolutionary history. In this study, ancient DNA analysis using real-time polymerase chain reaction (qPCR), combined with conventional PCR, was applied to the remains of twenty-four ancient head lice and their eggs from the Roman period which were recovered from Israel...
2016: PloS One
https://www.readbyqxmd.com/read/27707816/dose-dependent-effects-of-sirna-mediated-inhibition-of-scap-on-pcsk9-ldlr-and-plasma-lipids-in-mouse-and-rhesus-monkey
#10
Kristian K Jensen, Marija Tadin-Strapps, Sheng-Ping Wang, James Hubert, Yanqing Kan, Yong Ma, David G McLaren, Stephen F Previs, Kithsiri B Herath, Ablatt Mahsut, Andy Liaw, Shubing Wang, Steven J Stout, CarolAnn Keohan, Gail Forrest, David Coelho, Satya Yendluri, Stephanie Williams, Martin Koser, Steven Bartz, Karen O Akinsanya, Shirly Pinto
SREBP cleavage-activating protein (SCAP) is a key protein in the regulation of lipid metabolism and a potential target for treatment of dyslipidemia. SCAP is required for activation of the transcription factors SREBP-1 and -2. SREBPs regulate the expression of genes involved in fatty acid and cholesterol biosynthesis, and LDL-C clearance through the regulation of LDL receptor (LDLR) and PCSK9 expression. To further test the potential of SCAP as a novel target for treatment of dyslipidemia, we used siRNAs to inhibit hepatic SCAP expression and assess the effect on PCSK9, LDLR, and lipids in mice and rhesus monkeys...
December 2016: Journal of Lipid Research
https://www.readbyqxmd.com/read/27663909/epidemiology-microbiology-clinical-characteristics-and-outcomes-of-candidemia-in-internal-medicine-wards-a-retrospective-study
#11
Noa Eliakim-Raz, Roi Babaoff, Dafna Yahav, Shirly Yanai, Hila Shaked, Jihad Bishara
BACKGROUND: The clinical characteristics of internal medicine ward (IMW) patients with candidemia are unclear. The aim of this study was to define the clinical characteristics of candidemic IMW patients and to study the incidence, species distribution, and outcomes of these patients compared to surgical and intensive care unit (ICU) candidemic patients. METHODS: A retrospective cohort of candidemic patients in IMWs, general surgery wards, and an ICU at Beilinson Hospital during the period 2007-2014 was analyzed...
September 20, 2016: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/27639575/the-kaposi-s-sarcoma-associated-herpesvirus-orf35-gene-product-is-required-for-efficient-lytic-virus-reactivation
#12
Shir Bergson, Inbal Itzhak, Talya Wasserman, Anastasia Gelgor, Inna Kalt, Ronit Sarid
Kaposi's sarcoma-associated herpesvirus (KSHV) is implicated in the etiology of several human malignancies. KSHV open reading frame (orf) 35 encodes a conserved gammaherpesvirus protein with an, as yet, unknown function. Employing the bacterial artificial chromosome (BAC) system, we generated a recombinant viral clone that fails to express ORF35 (BAC16-ORF35-stop) but preserves intact adjacent and overlapping reading frames. Using this construct, we studied the role of this previously uncharacterized gene product during lytic reactivation of KSHV...
September 15, 2016: Virology
https://www.readbyqxmd.com/read/27630454/effectiveness-of-flow-inflating-device-in-providing-continuous-positive-airway-pressure-for-critically-ill-children-in-limited-resource-settings-a-prospective-observational-study
#13
G Fatima Shirly Anitha, Lakshmi Velmurugan, Shanthi Sangareddi, Krishnamurthy Nedunchelian, Vinoth Selvaraj
BACKGROUND AND AIMS: Noninvasive ventilation (NIV) is an emerging popular concept, which includes bi-level positive airway pressure or continuous positive airway pressure (CPAP). In settings with scarce resources for NIV machines, CPAP can be provided through various indigenous means and one such mode is flow inflating device - Jackson-Rees circuit (JR)/Bain circuit. The study analyses the epidemiology, various clinical indications, predictors of CPAP failure, and stresses the usefulness of flow inflating device as an indigenous way of providing CPAP...
August 2016: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/27628341/selmap-selex-affinity-landscape-mapping-of-transcription-factor-binding-sites-using-integrated-microfluidics
#14
Dana Chen, Yaron Orenstein, Rada Golodnitsky, Michal Pellach, Dorit Avrahami, Chaim Wachtel, Avital Ovadia-Shochat, Hila Shir-Shapira, Adi Kedmi, Tamar Juven-Gershon, Ron Shamir, Doron Gerber
Transcription factors (TFs) alter gene expression in response to changes in the environment through sequence-specific interactions with the DNA. These interactions are best portrayed as a landscape of TF binding affinities. Current methods to study sequence-specific binding preferences suffer from limited dynamic range, sequence bias, lack of specificity and limited throughput. We have developed a microfluidic-based device for SELEX Affinity Landscape MAPping (SELMAP) of TF binding, which allows high-throughput measurement of 16 proteins in parallel...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27611215/dual-energy-contrast-enhanced-spectral-mammography-enhancement-analysis-on-bi-rads-4-non-mass-microcalcifications-in-screened-women
#15
Yun-Chung Cheung, Yu-Hsiang Juan, Yu-Ching Lin, Yung-Feng Lo, Hsiu-Pei Tsai, Shir-Hwa Ueng, Shin-Cheh Chen
BACKGROUND: Mammography screening is a cost-efficient modality with high sensitivity for detecting impalpable cancer with microcalcifications, and results in reduced mortality rates. However, the probability of finding microcalcifications without associated cancerous masses varies. We retrospectively evaluated the diagnosis and cancer probability of the non-mass screened microcalcifications by dual-energy contrast-enhanced spectral mammography (DE-CESM). PATIENTS AND METHODS: With ethical approval from our hospital, we enrolled the cases of DE-CESM for analysis under the following inclusion criteria: (1) referrals due to screened BI-RADS 4 microcalcifications; (2) having DE-CESM prior to stereotactic biopsy; (3) no associated mass found by sonography and physical examination; and (4) pathology-based diagnosis using stereotactic vacuum-assisted breast biopsy...
2016: PloS One
https://www.readbyqxmd.com/read/27608168/low-levels-of-calcium-or-vitamin-d-which-is-more-important-in-systemic-lupus-erythematosus-patients-an-extensive-data-analysis
#16
Abdulla Watad, Shmuel Tiosano, Shir Azrielant, Aaron Whitby, Doron Comaneshter, Arnon D Cohen, Yehuda Shoenfeld, Howard Amital
OBJECTIVES: Several reports have indicated an association between systemic lupus erythematosus (SLE) and low levels of vitamin D. We examined several blood work parameters in SLE patients and controls and performed an extensive data analysis in order to investigate the links between blood levels of calcium, vitamin D, and SLE disease. METHODS: 4,278 SLE patients and 16,443 age and sex-matched controls were selected from a national health insurer database in Israel...
August 31, 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27590807/transposon-mutagenesis-identifies-genes-critical-for-growth-of-pseudomonas-nitroreducens-tx1-on-octylphenol-polyethoxylates
#17
Tuan Ngoc Nguyen, Chen-Wei Yeh, Po-Chun Tsai, Kyoung Lee, Shir-Ly Huang
Pseudomonas nitroreducens TX1 is of special interest because of its ability to utilize 0.05% to 20% octylphenol polyethoxylates (OPEOn) as a sole source of carbon. In this study, a library containing 30,000 Tn5-insertion mutants of the wild-type strain TX1 was constructed and screened for OPEOn utilization, and 93 mutants were found to be unable to grow on OPEOn In total, 42 separate disrupted genes were identified, and the proteins encoded by the genes were then classified into various categories, namely, information storage and processing (14...
November 15, 2016: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/27569369/a-step-wise-approach-for-analysis-of-the-mouse-embryonic-heart-using-17-6tesla-mri
#18
Rinat Gabbay-Benziv, E Albert Reece, Fang Wang, Amnon Bar-Shir, Chris Harman, Ozhan M Turan, Peixin Yang, Sifa Turan
BACKGROUND: The mouse embryo is ideal for studying human cardiac development. However, laboratory discoveries do not easily translate into clinical findings partially because of histological diagnostic techniques that induce artifacts and lack standardization. AIM: To present a step-wise approach using 17.6T MRI, for evaluation of mice embryonic heart and accurate identification of congenital heart defects. SUBJECTS: 17.5-embryonic days embryos from low-risk (non-diabetic) and high-risk (diabetic) model dams...
August 26, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27547023/flexible-plasmonic-sensors
#19
Daniel Shir, Zachary S Ballard, Aydogan Ozcan
Mechanical flexibility and the advent of scalable, low-cost, and high-throughput fabrication techniques have enabled numerous potential applications for plasmonic sensors. Sensitive and sophisticated biochemical measurements can now be performed through the use of flexible plasmonic sensors integrated into existing medical and industrial devices or sample collection units. More robust sensing schemes and practical techniques must be further investigated to fully realize the potentials of flexible plasmonics as a framework for designing low-cost, embedded and integrated sensors for medical, environmental, and industrial applications...
July 2016: IEEE Journal of Selected Topics in Quantum Electronics
https://www.readbyqxmd.com/read/27530927/outcomes-of-early-versus-delayed-cholecystectomy-in-patients-with-mild-to-moderate-acute-biliary-pancreatitis-a-randomized-prospective-study
#20
Shir Li Jee, Razman Jarmin, Kin Foong Lim, Krishnan Raman
BACKGROUND: In patients with acute biliary pancreatitis (ABP), cholecystectomy is mandatory to prevent further biliary events, but the precise timing of cholecystectomy for mild to moderate disease remain a subject of ongoing debate. The aim of this study is to assess the outcomes of early versus delayed cholecystectomy. We hypothesize that early cholecystectomy as compared to delayed cholecystectomy reduces recurrent biliary events without a higher peri-operative complication rate. METHODS: Patients with mild to moderate ABP were prospectively randomized to either an early cholecystectomy versus a delayed cholecystectomy group...
August 13, 2016: Asian Journal of Surgery
keyword
keyword
17965
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"