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thyroid incidentaloma

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https://www.readbyqxmd.com/read/28261999/cytological-evaluation-by-fine-needle-aspiration-biopsy-of-incidental-focal-increased-fluorodeoxyglucose-uptake-in-thyroid-on-positron-emission-tomography-scan
#1
Yanchun Li, Min Cui, Nami Azar, Dean Nakamoto, Claire W Michael
BACKGROUND: With the increased use of whole body fluorodeoxyglucose positron emission tomography (PET) scan for staging/restaging or primary diagnosis of neoplasia, thyroid incidentalomas have become more common. The limited reports of PET-positive thyroid incidentalomas showed incidence of malignancy ranging from 14 to 66%, and there is discrepancy in terms of the diagnostic significance of the standard uptake value (SUV) value. METHODS: This is a retrospective study of 20 PET incidentalomas which had cytological evaluation from October 2009 to February 2015 at a tertiary care university medical center, M:F = 8:12...
March 6, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28259145/ultrasonographic-prevalence-and-characteristics-of-non-palpable-thyroid-incidentalomas-in-a-hospital-based-population-in-a-sub-saharan-country
#2
Boniface Moifo, Jean Roger Moulion Tapouh, Sylviane Dongmo Fomekong, François Djomou, Emmanuella Manka'a Wankie
BACKGROUND: Thyroid incidentalomas (TI) are highly prevalent asymptomatic thyroid nodules with ultrasound as the best imaging modality for their detection and characterization. Although they are mostly benign, potential for malignancy is up to 10-15%. In sub-Saharan Africa little data exists on the prevalence and risk categorization of TI. The aim of this study was to determine the prevalence and ultrasound characteristics of non-palpable thyroid incidentalomas among adults in sub-Saharan setting...
March 4, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28255974/thyroid-lesions-in-patients-with-acromegaly-case-control-study-and-update-to-the-meta-analysis
#3
Kosma Woliński, Adam Stangierski, Edyta Gurgul, Barbara Bromińska, Agata Czarnywojtek, Martha Lodyga, Marek Ruchała
INTRODUCTION: Acromegaly results from oversecretion of growth hormone and subsequently insulin growth factor-1. According to some authors, the disease can cause increased prevalence of nodular goitre and thyroid cancer (TC). However, the number of studies comparing acromegalic patients with control groups is low. We aimed to assess the prevalence of thyroid lesions in patients with acromegaly in comparison to an age- and sex-matched control group and to update the meta-analysis previously performed in our department by the same authors...
2017: Endokrynologia Polska
https://www.readbyqxmd.com/read/28185344/incidental-and-nonincidental-canine-thyroid-tumors-assessed-by-multidetector-row-computed-tomography-a-single-centre-cross-sectional-study-in-4520-dogs
#4
Giovanna Bertolini, Michele Drigo, Luca Angeloni, Marco Caldin
Thyroid nodules are common in dogs and are increasingly likely to be detected with the increased use of advanced imaging modalities. An unsuspected, nonpalpable, asymptomatic lesion, defined as a thyroid incidentaloma, may be discovered on an imaging study unrelated to the thyroid gland. The objective of this single-center cross-sectional study was to assess the prevalence and computed tomography (CT) characteristics of incidental and nonincidental thyroid tumors in a large population of dogs, using prospective recruitment of patients undergoing CT examination for various reasons during the period of 2005-2015...
February 9, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28041586/thyroid-nodules-%C3%AE-guide-to-assessment-treatment-and-follow-up
#5
REVIEW
Stavroula Α Paschou, Andromachi Vryonidou, Dimitrios G Goulis
Thyroid nodules constitute by far the most common disorder of the endocrine system. Epidemiological studies have indicated that approximately 5% of women and 1% of men resident in iodine-sufficient areas have palpable thyroid nodules. However, by the age of 60 years about 50% of the general population is estimated to have at least one thyroid nodule. Indeed, the reported prevalence of a "thyroid incidentaloma" is up to 70% when neck/carotid artery ultrasound, computed tomography (CT) or magnetic resonance imaging (MRI) is performed for other indications...
February 2017: Maturitas
https://www.readbyqxmd.com/read/27758132/a-novel-thyroid-hormone-receptor-beta-gene-mutation-g251v-in-a-thai-patient-with-resistance-to-thyroid-hormone-coexisting-with-pituitary-incidentaloma
#6
Chutintorn Sriphrapradang, Panudda Srichomkwun, Samuel Refetoff, Sunee Mamanasiri
A patient is reported with resistance to thyroid hormone beta caused by a novel THRB gene mutation and coexisting pituitary microadenoma. A 41-year-old Thai woman presented with elevated serum thyroid hormone levels and non-suppressed thyrotropin (TSH). Magnetic resonance imaging showed a 4 mm × 2 mm pituitary adenoma. Five of her relatives had similar thyroid tests abnormalities, but a sister had Graves' disease. Thyroperoxidase and thyroglobulin antibodies were positive in all affected family members, except for the proband's 4...
December 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27696232/correlation-of-braf-mutation-and-suvmax-levels-in-thyroid-cancer-patients-incidentally-detected-in-18-f-fluorodeoxyglucose-positron-emission-tomography
#7
Aysenur Ozderya, Sule Temizkan, Aylin Ege Gul, Sule Ozugur, Mehmet Sargin, Kadriye Aydin
The prognostic importance of (18)F-fluorodeoxyglucose avidity in primary thyroid tumor and molecular basis responsible for its mechanism has not yet been well characterized. In this study, we aimed to evaluate the correlation between the maximum standardized uptake levels and B-type Raf kinase mutation positivity in incidentally detected papillary thyroid cancer patients during (18)F-fluorodeoxyglucose positron emission tomography examination. We retrospectively evaluated 6873 (18)F-fluorodeoxyglucose-positron emission tomography scans of consecutive subjects from a database search for tumor staging in 2014 at our hospital Nuclear Medicine Center...
January 2017: Endocrine
https://www.readbyqxmd.com/read/27612034/the-incidence-of-thyroid-cancer-in-focal-hypermetabolic-thyroid-lesions-an-18f-fdg-pet-ct-study-in-more-than-6000-patients
#8
Martin Barrio, Johannes Czernin, Michael W Yeh, Miguel F Palma Diaz, Pawan Gupta, Martin Allen-Auerbach, Christiaan Schiepers, Ken Herrmann
BACKGROUND: The clinical significance of incidental thyroid abnormalities discovered in fluorine-18 fluorodeoxyglucose (F-FDG) PET/computed tomography (CT) (FDG PET/CT) studies remains controversial. The aim of this large retrospective study was to (a) determine the prevalence of focal F-FDG thyroid uptake on whole-body F-FDG PET/CT studies carried out for nonthyroid cancers and (b) to test whether intense focal F-FDG thyroid uptake is associated with malignancy. MATERIALS AND METHODS: A total of 11 921 F-FDG PET/CT studies in 6216 patients carried out at our institution between January 2012 and December 2014 were analyzed...
December 2016: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/27571130/fluorine-18-fluorodeoxyglucose-avid-thyroid-incidentalomas-on-pet-ct-scan-in-cancer-patients-how-sinister-are-they
#9
Aamna Hassan, Saima Riaz, Waleed Zafar
OBJECTIVE: To evaluate the prevalence of malignancy in incidental thyroidal uptake on PET with fluorine-18 deoxyglucose integrated with computed tomography (F-FDG PET/CT) in Pakistani cancer patients and to assess the role of standardized uptake value (SUV) in deciding which lesions to investigate further. METHOD: We retrospectively reviewed all patients who underwent F-FDG PET/CT scans over a period of 59 months and further analysed those with visually increased thyroidal uptake...
October 2016: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/27513265/the-incidence-of-18f-fdg-pet-ct-thyroid-incidentalomas-andthe-prevalence-of-malignancy-a-prospective-study
#10
Mine Şencan Eren, Özhan Özdoğan, Arzu Gedik, Mehmet Ceylan, Merih Güray Durak, Mustafa Seçil, Mehmet Ali Koçdor, Abdurrahman Çömlekçi, Hatice Durak
BACKGROUND/AIM: To determine the prevalence of malignancy in thyroid incidentalomas (TIs) detected by fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT). MATERIALS AND METHODS: 18F-FDG PET/CT images were evaluated prospectively for the presence of thyroid uptake. The patients with a TI were evaluated by an endocrinologist according to the predefined diagnostic algorithm. The final diagnosis was obtained clinically and/or by pathology...
2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27504349/diagnostic-dilemma-in-a-thyroid-incidentaloma-second-primary-versus-metastatic-nodule
#11
Abid Ali Mirza, Esha Pai, Kodaganur Gopinath Srinivas, Shankarappa Amarendra, K S Gopinath
With the increasing use of 18F-Fluro-Deoxyglucose (FDG) Positron Emission Tomography (PET) the number of thyroid incidentalomas is on the rise. Focal thyroid incidentalomas identified by FDG-PET have been reported to have a high incidence of malignancy. Neuroendocrine tumours of the thyroid are rare entities. The most common neuroendocrine tumour of the thyroid is medullary carcinoma. A thyroid nodule in a patient with a known neuroendocrine tumour must be differentiated from a primary medullary carcinoma which can present as a diagnostic challenge to the clinician...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27424217/simultaneous-pet-mri-vs-pet-ct-in-oncology-a-systematic-review
#12
C Riola-Parada, L García-Cañamaque, V Pérez-Dueñas, M Garcerant-Tafur, J L Carreras-Delgado
OBJECTIVE: The aim of this review was to evaluate the diagnostic performance of simultaneous PET/MRI in oncology compared with that of PET/CT, based upon the available evidence. MATERIAL AND METHODS: A systematic search was performed in the Medline and Embase databases to identify original clinical articles published up to 21 January 2016, in order to compare simultaneous PET/MRI and PET/CT in oncology patients. RESULTS: A total of 57 articles were obtained that included various diseases: head and neck cancer (5), lung cancer and lung nodules (13), colorectal cancer (1), liver lesions (2), abdominal incidentalomas (1), neuroendocrine tumours (2), thyroid carcinoma (2), breast cancer (3), gynaecological cancer (2), prostate cancer (4), lymphoma (2), multiple myeloma (1), bone metastases (3), intracranial tumours (2), paediatric oncology (1) and various tumours (13)...
September 2016: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/27230389/charting-a-course-through-the-ceas-diagnosis-and-management-of-medullary-thyroid-cancer
#13
Christopher W Rowe, Cino Bendinelli, Shaun McGrath
Medullary thyroid cancer (MTC) is an uncommon thyroid cancer that requires a high index of suspicion to facilitate diagnosis of early-stage disease amenable to surgical cure. The challenges of diagnosis, as well as management in the setting of persistent disease, are explored in the context of a case presenting with the incidental finding of elevated carcinoembryonic antigen (CEA) and an (18) F-fluorodeoxyglucose positron emission tomography ((18) F-FDG-PET)-positive thyroid incidentaloma detected following treatment of colorectal cancer...
September 2016: Clinical Endocrinology
https://www.readbyqxmd.com/read/27146775/positron-emission-tomography-thyroid-incidentaloma-is-it-different-in-indian-subcontinent
#14
R Vaish, R Venkatesh, D A Chaukar, A D Deshmukh, N C Purandare, A K D'cruz
BACKGROUND: Positron emission tomography (PET) forms an integral part in work-up and follow-up of various malignancies. With the increased use of PET in oncology, finding of an incidental focal thyroid uptake (incidentaloma) is not unusual and presents a diagnostic challenge. AIM: The aim of the following study is to evaluate the frequency and radio-pathologic correlation of focal 18-fluoro deoxyglucose uptake (FDG) on PET within the thyroid from a large series...
January 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/27028799/developing-a-registry-for-thyroid-incidentalomas-lessons-learned-and-the-path-forward
#15
Louise Davies, Erin Pichiotino, William C Black, Anna N A Tosteson
BACKGROUND: Incidentalomas are findings on an imaging test done for other reasons, for which there are no matching symptoms in the patient. They are common in the adrenal gland, pancreas, liver, and thyroid, among other sites. Incidentalomas are a problem because we have a limited understanding of their natural history: it is difficult to know how much of a threat they pose to individual patients. An observational registry that would allow a systematic study of thyroid incidentalomas could reveal their natural history and the effect of detection on patients' lives, as well as document the cost to the healthcare system...
May 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/26963467/clinical-significance-of-thyroid-incidentalomas-identified-by-18f-fdg-pet-ct-correlation-of-ultrasonograpy-findings-with-cytology-results
#16
COMPARATIVE STUDY
Özgür Demir, Naziyet Köse, Elgin Özkan, Uğur Ünlütürk, Gülseren Aras, Murat Faik Erdoğan
AIM: The aim of this study was to investigate the clinical importance of incidental focal or diffuse fluorine-18 fluorodeoxyglucose (F-FDG) uptake in the thyroid gland on positron emission tomography (PET)/computed tomography (CT) and to evaluate the additive value of thyroid ultrasonography (US) in defining the malignancy potential of thyroid incidentalomas. PATIENTS AND METHODS: A total of 1450 patients, who had undergone a PET/CT scan for staging or restaging of various malignancies, were screened retrospectively and 52 (3...
July 2016: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/26919607/thyroid-nodules-detected-by-contrast-enhanced-magnetic-resonance-angiography-prevalence-and-clinical-significance
#17
Hyun Kyung Lim, Sung Tae Park, Hongil Ha, Seo-youn Choi
BACKGROUND AND PURPOSE: Incidental thyroid lesions are frequently found on contrast-enhanced magnetic resonance (CE-MR) angiography. The purpose of this study is to determine the prevalence of thyroid incidentalomas detected by CE-MR angiography and to evaluate their clinical significance by correlation with ultrasound (US) and cytopathological results. MATERIALS AND METHODS: We retrospectively reviewed 3,299 consecutive CE-MR angiography examinations performed at our institution between January 2010 and March 2013...
2016: PloS One
https://www.readbyqxmd.com/read/26904704/the-importance-of-exclusion-of-obstructive-sleep-apnea-during-screening-for-adrenal-adenoma-and-diagnosis-of-pheochromocytoma
#18
Alicia C Weeks, Michelle E Kimple, Dawn Belt Davis
Context. As catecholamine elevation is a key element in the diagnosis of pheochromocytoma, more commonplace causes of sympathetic excess, such as obstructive sleep apnea (OSA), should be excluded as standard practice prior to diagnosis. This is essential to avoid misdiagnosis of adrenal incidentalomas identified in the estimated 42 million Americans with OSA, with greater than 4 million projected to undergo a computed tomography study annually. Case Description. A 56-year-old woman presented with a several year history of paroxysmal hypertension, palpitations, and diaphoresis...
July 2015: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/26556493/-do-not-always-puncture-a-thyroid-nodule
#19
REVIEW
Bart Dorgelo, Johannes W A Smit, Thera P Links
The incidence of thyroid cancer is increasing, especially the papillary subtype. This increase can be mainly attributed to the detection of small - mostly indolent - papillary thyroid cancers as a consequence of the higher sensitivity of diagnostic techniques and the more frequent use of diagnostic applications. Two patients are described with (non-)palpable thyroid nodules to illustrate the risk of overdiagnostics and overtreatment. A thyroid incidentaloma detected on ultrasound, CT or MRI does not require further diagnostic procedures as standard...
2015: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/26508893/management-of-a-thyroid-incidentaloma-in-a-patient-with-cancer-a-case-report
#20
Charles Dearman, Esme J Hill, Jamie M Franklin, Greg P Sadler, Lai Mun Wang, Michael A Silva, Ricky A Sharma
The routine use of (18)F-fluorodeoxyglucose-positron emission tomography (PET)/computed tomography scans for staging and assessment of treatment response for cancer has resulted in a large number of thyroid abnormalities being detected as incidental findings ("incidentalomas"). Since most PET/CT scans are performed in the setting of a known nonthyroid malignancy, the need for "incidentalomas" to be further investigated and managed depends on the stage, prognosis, and current treatment plan for the known malignancy...
2015: International Medical Case Reports Journal
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