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thyroid incidentaloma

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https://www.readbyqxmd.com/read/29759033/thyroid-incidentalomas-detected-on-18f-fdg-pet-ct-malignant-risk-stratification-and-management-plan
#1
Sae Rom Chung, Young Jun Choi, Chong Hyun Suh, Hwa Jung Kim, Jong Jin Lee, Won Gu Kim, Tae-Yon Sung, Yu-Mi Lee, Dong Eun Song, Jeong Hyun Lee, Jung Hwan Baek
BACKGROUND: To stratify the risk of malignancy in thyroid incidentalomas detected on 18F-FDG PET/CT using ultrasound features according to guidelines for thyroid nodules and thereby suggests management plans. METHODS: From a historical cohort of 96 942 consecutive patients who underwent 18F-FDG PET/CT between October 2008 and September 2015, 1342 patients with 1364 nodules underwent ultrasound evaluation for focal uptake in thyroid gland, with a final diagnosis made for 877 patients with 907 nodules which included in our study...
May 15, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29644341/uptake-of-99m-tc-mibi-by-sclerosing-pneumocytoma-raising-a-false-suspicion-of-metastasis-from-medullary-thyroid-carcinoma
#2
Georgios E Papadakis, Flavian Tabotta, Igor Levotanec, Michel Gonzalez, John O Prior, Stefano La Rosa, Gerasimos P Sykiotis
Technetium-99m methoxy isobutyl isonitrile (99m Tc-MIBI; sestamibi) single-photon emission computed tomography (SPECT)/computed tomography (CT) performed for preoperative localization of parathyroid adenomas or for other indications can reveal incidentalomas. Interpretation of such findings can be challenging, particularly when thyroid or other endocrine tumors are also present. Preoperative staging of a 59-year-old female patient with medullary thyroid carcinoma (MTC) showing moderate hypermetabolism on 18 F-fluorodeoxyglucose positron emission tomography/CT also detected a slightly hypermetabolic pulmonary nodule (standardized uptake value normalized by body weight max = 2...
April 1, 2018: Journal of the Endocrine Society
https://www.readbyqxmd.com/read/29522260/comparison-of-incidental-versus-palpable-thyroid-nodules-presenting-for-fine-needle-aspiration-biopsy
#3
Ayaka J Iwata, Arti Bhan, Sharon Lahiri, Amy M Williams, Andrew R Taylor, Steven S Chang, Michael C Singer
BACKGROUND: Many attribute the rise in incidence of thyroid cancer to a deluge of radiologically identified incidental thyroid nodules. The clinical implications are unclear. METHODS: A review was performed of all patients who underwent fine-needle aspirations of thyroid nodules by our academic medical center's Endocrinology Division between 2006 and 2010. Medical records were reviewed to identify whether the thyroid nodule was discovered incidentally or by palpation...
March 9, 2018: Head & Neck
https://www.readbyqxmd.com/read/29520193/diagnostic-value-of-volume-based-fluorine-18-fluorodeoxyglucose-pet-ct-parameters-for-characterizing-thyroid-incidentaloma
#4
Huazheng Shi, Zuguo Yuan, Zheng Yuan, Chunshan Yang, Jian Zhang, Yi Shou, Wenrui Zhang, Zhaofu Ping, Xin Gao, Shiyuan Liu
Objective: To assess clinical value of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) for differentiation of malignant from benign focal thyroid incidentaloma. Materials and Methods: This retrospective study included 99 patients with focal thyroid incidentaloma of 5216 non-thyroid cancer patients that had undergone PET/CT. PET/CT semi-quantitative parameters, volume-based functional parameters, metabolic tumor volume (MTV), and total lesion glycolysis (TLG) of thyroid incidentaloma were assessed...
March 2018: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/29495350/the-role-of-insulin-resistance-hyperinsulinism-on-the-rising-trend-of-thyroid-and-adrenal-nodular-disease-in-the-current-environment
#5
REVIEW
Agathocles Tsatsoulis
Thyroid follicular cells, as well as adrenocortical cells, are endowed by an intrinsic heterogeneity regarding their growth potential, in response to various stimuli. This heterogeneity appears to constitute the underlying cause for the focal cell hyperplasia and eventually the formation of thyroid and adrenal nodules, under the influence of growth stimulatory factors. Among the main stimulatory factors are the pituitary tropic hormones, thyroid-stimulating hormone (TSH) or thyrotropin and adrenocorticotropic hormone (ACTH), which regulate the growth and function of their respective target cells, and the insulin/insulin-like growth factor system, that, through its mitogenic effects, can stimulate the proliferation of these cells...
February 26, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29431057/evolution-in-the-management-of-thyroid-cancer-an-observational-study-in-two-referral-centres-in-belgium
#6
Bernard Peene, Annick Van den Bruel, Carolien Moyson, Brigitte Decallonne
Objective Thyroid cancer incidence is increasing. The rise is most pronounced for microcancers (≤10 mm, T1a). In 2006, landmark European and American guidelines for the management of thyroid cancer were published. We studied thyroid cancer characteristics and initial management before and after 2006. Methods We conducted a retrospective observational study of non-medullary thyroid cancer patients that underwent thyroidectomy in two Belgian referral centres comparing pre-, per- and post-operative management in a cohort before and after 2006...
February 12, 2018: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29025986/18f-fluorodeoxyglycose-avid-thyroid-incidentalomas-the-importance-of-contextual-interpretation
#7
David A Pattison, Michael Bozin, Alexandra Gorelik, Michael S Hofman, Rodney J Hicks, Anita Skandarajah
Background: FDG-avid thyroid incidentalomas (TI) are seen in approximately 2.5% of patients imaged for staging or response assessment of malignancy and represent thyroid cancer in approximately 35% of cases. Consequently, the 2015 ATA guidelines strongly recommend investigation of all FDG-avid nodules ≥1cm with US and fine needle aspiration cytology (FNA). This study aims to assess the overall and thyroid cancer specific survival in a large cohort of patients with FDG-avid TI with long-term follow-up to assess the validity of this approach...
October 12, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28976331/thyroid-incidentalomas-on-18-f-fdg-pet-ct-clinical-significance-and-controversies
#8
William Makis, Anthony Ciarallo
OBJECTIVE: The purpose of the current study is to examine the incidence and clinical significance of unexpected focal uptake of (18)F-fluorodeoxyglucose ((18)F-FDG) on positron emission tomography/computed tomography (PET/CT) in the thyroid gland of oncology patients, the maximum standardized uptake value (SUVmax) of benign and malignant thyroid incidentalomas in these patients, and review the literature. METHODS: Seven thousand two hundred fifty-two (18)F-FDG PET/CT studies performed over four years, were retrospectively reviewed...
October 3, 2017: Molecular Imaging and Radionuclide Therapy
https://www.readbyqxmd.com/read/28913004/hypermetabolic-thyroid-incidentaloma-on-positron-emission-tomography-review-of-laboratory-radiologic-and-pathologic-characteristics
#9
Mehrdad Bakhshayesh Karam, Abtin Doroudinia, Farzaneh Joukar, Kobra Nadi, Atosa Dorudinia, Payam Mehrian, Abbas Yousefikoma
INTRODUCTION: Incidental hypermetabolic thyroid lesions on Positron Emission Tomography have significant clinical value and may harbor malignancy. In this study we evaluated laboratory, radiologic, and pathologic characteristics of incidental hypermetabolic thyroid lesions. MATERIALS AND METHODS: We evaluated 18 patients prospectively with various malignancies and hypermetabolic thyroid incidentaloma. The thyroid function tests, ultrasound assessment, and guided FNA biopsy were performed on all cases...
2017: Journal of Thyroid Research
https://www.readbyqxmd.com/read/28791924/comparison-of-core-needle-biopsy-and-fine-needle-aspiration-for-evaluating-thyroid-incidentalomas-detected-by-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-a-propensity-score-analysis
#10
Chong Hyun Suh, Young Jun Choi, Jong Jin Lee, Woo Hyun Shim, Jung Hwan Baek, Han Cheol Chung, Young Kee Shong, Dong Eun Song, Tae Yon Sung, Jeong Hyun Lee
BACKGROUND: This study used a propensity score analysis to assess the roles of core-needle biopsy (CNB) and fine-needle aspiration (FNA) in the evaluation of thyroid incidentalomas detected on 18 F-fluorodeoxyglucose positron emission tomography/computed tomography (18 F-FDG PET/CT). METHODS: The study population was obtained from a historical cohort who underwent 18 F-FDG PET/CT between October 2008 and September 2015. Patients were included who underwent ultrasound-guided CNB or FNA for incidental focal uptake of 18 F-FDG in the thyroid gland on PET/CT...
October 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28789759/-work-up-of-thyroid-incidentalomas-identified-by-18-f-fluorodeoxyglucose-pet-ct
#11
Ali Asmar, Lene Simonsen, Jens Bülow, Meena Asmar
Several reports have described dramatic increase over recent decades in the incidence of thyroid cancer, even as thyroid cancer-related mortality rates have not changed substantially. Nevertheless, in several retrospective studies the incidence of malignancy in focal (18)F-fluorodeoxyglucose (FDG) thyroid uptake discovered on whole body (18)F-FDG PET/CT, carried out for non-thyroid cancers, is 13-64%. Our aim was to design a practical algorithm for management of an increasing number of thyroid incidentalomas, identified by (18)F-FDG PET/CT...
July 17, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28718944/the-effect-of-routine-radiological-reporting-of-thyroid-incidentalomas-on-rates-of-thyroid-needle-biopsy-thyroid-surgery-and-detection-of-thyroid-malignancy
#12
J D Sinnott, R Mortimer, J Smith, E Skelton, K Drinkwater, D Lipscomb, D C Howlett
OBJECTIVE: This study looked at the effect of a changing radiology reporting policy to routinely review the thyroid gland where visible and report on any thyroid lesion, recommending further investigation as appropriate. CONTEXT: Incidentaloma is a term used to describe a lesion found on imaging unrelated to the clinical issue under investigation. There is variability in the radiological reporting of thyroid incidentalomas and conflicting recommendations as to how these lesions should be managed...
December 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28680214/ectopic-parathyroid-incidentaloma-on-tc99m-sestamibi-myocardial-perfusion-imaging
#13
Rola Aatif Hasan Hussain, Ammar Mohammed Saeed Ali, K Manivannan, S K Chirala
Parathyroid incidentalomas are generally discovered during thyroid surgery.([1]) In the present case, the ectopic parathyroid adenoma was discovered as an incidentaloma in a clinical setting, during the course of clinical evaluation of atypical chest pain by gastroenterology and cardiology.
July 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28649084/malignancy-rate-of-focal-thyroid-incidentaloma-detected-by-fdg-pet-ct-results-of-a-prospective-cohort-study
#14
Philippe Thuillier, Nathalie Roudaut, Geneviève Crouzeix, Marie Cavarec, Philippe Robin, Ronan Abgral, Véronique Kerlan, Pierre-Yves Salaun
OBJECTIVE: To evaluate the malignancy rate of focal thyroid incidentaloma (fTI) in a population of patients undergoing a 18F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) for a non-thyroid purpose. DESIGN: We conducted a prospective cohort study from January 2013 to November 2014. All consecutive patients referred for a FDG PET-CT were prospectively screened. Patients with known neoplastic thyroid disease were excluded from the analysis...
August 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28588814/coincidence-of-follicular-lymphoma-and-hurtle-cell-thyroid-carcinoma-in-a-patient-at-presentation-which-one-is-the-source-of-bone-metastasis-case-report-and-review-of-the-literature
#15
Hasan Atilla Ozkan, Arda Akoluk, Turhan Ozler, Isin Dogan Ekici, Nalan Alan Selcuk
Thyroid incidentaloma is defined as a new identified thyroid lesion occasionally detected during imaging studies. Incidence of thyroid incidentalomas is relatively rare in patients with lymphoma. Because of high rate of malignancy, these lesions with high intensity focal (18) FDG uptake detected on positron emission tomography with computed tomography (PET/CT) should undergo to biopsy regardless of size.
June 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28585593/incidentaloma-from-general-practice-to-specific-endocrine-frame
#16
Ancuta Augustina Gheorghisan-Galateanu, Mara Carsote, Ana Valea
Incidentaloma, a modern concept connected to technology progress, represents an accidentally discovered tumour, usually used for hypophysis and adrenals, and rarely for thyroid, parathyroids, and ovaries. This is a narrative review based on PubMed research, between 2012 and 2016 focusing on general and endocrine approach and current controversies. Main dilemma is the terminology itself: randomly imagery finding is enough or non-functioning profile and low-growth rate (not requiring surgery) should be mandatory? The controversies refers to best time framing of re-scanning pituitary and adrenal incidentaloma and setting of clear criteria for subclinical Cushing's syndrome...
June 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28408111/management-of-pet-diagnosed-thyroid-incidentalomas-in-british-columbia-canada-critical-importance-of-the-pet-report
#17
Jordan Wong, Kaidi Liu, Celia Siu, Steven Jones, Marlise Sovka, Don Wilson, Sam M Wiseman
BACKGROUND: PET diagnosed thyroid incidentalomas (TI) should undergo prompt evaluation due to a high risk of underlying malignancy. Our study reviewed physician management of PET diagnosed TIs in British Columbia (BC), Canada. METHODS: All PET reports from BC between 2011 and 2014 were reviewed. Clinical and demographic data was obtained for TI patients through chart review and mail out surveys to physicians. Statistical analysis was performed to identify factors associated with further TI investigation...
May 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28353353/risk-of-malignancy-in-thyroid-incidentaloma-is-not-increased-in-overweight-or-obese-patients-but-in-young-patients
#18
Kyoungjune Pak, Seunghyeon Shin, So Jung Kim, Keunyoung Kim, Bum Soo Kim, Seong Jang Kim, Yun Kyung Jeon, Sang Soo Kim, Bo Hyun Kim, In-Joo Kim
Thyroid incidentaloma is defined as an unsuspected, asymptomatic thyroid lesion that is discovered on an imaging study or during an operation unrelated to the thyroid gland. We aim to evaluate the relationship between overweight or obese and risk of malignancy in patients with thyroid incidentaloma detected by F18-flurodeoxyglucose positron emission tomography/computed tomography and factors to predict risk of malignancy in thyroid incidentaloma. From January 2010 to December 2013, a total of 238 patients were eligible for this study...
May 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28320460/thyroid-incidentalomas-on-18fdg-pet-ct-a-metabolico-pathological-correlation
#19
N Hagenimana, J Dallaire, É Vallée, M Belzile
BACKGROUND: Thyroid incidentaloma is defined as an unsuspected thyroid lesion found on imaging study or while performing a surgery non-related to the thyroid gland. Most recent scientific literature tends to demonstrate a detection rate of 0.1-4.3% for incidental findings of thyroid focal uptake identified by18 F-fluorodeoxyglugose Positron Emission Tomography with computed tomography (18 FDG-PET/CT) initially prescribed for nonthyroid disease. From 10.3 to 80.0% of patients who underwent further evaluation are diagnosed with malignant lesions...
March 21, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28261999/cytological-evaluation-by-fine-needle-aspiration-biopsy-of-incidental-focal-increased-fluorodeoxyglucose-uptake-in-thyroid-on-positron-emission-tomography-scan
#20
Yanchun Li, Min Cui, Nami Azar, Dean Nakamoto, Claire W Michael
BACKGROUND: With the increased use of whole body fluorodeoxyglucose positron emission tomography (PET) scan for staging/restaging or primary diagnosis of neoplasia, thyroid incidentalomas have become more common. The limited reports of PET-positive thyroid incidentalomas showed incidence of malignancy ranging from 14 to 66%, and there is discrepancy in terms of the diagnostic significance of the standard uptake value (SUV) value. METHODS: This is a retrospective study of 20 PET incidentalomas which had cytological evaluation from October 2009 to February 2015 at a tertiary care university medical center, M:F = 8:12...
June 2017: Diagnostic Cytopathology
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