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https://www.readbyqxmd.com/read/29142398/cytotoxic-antimitotic-and-antiproliferation-studies-on-rasam-a-south-indian-traditional-functional-food
#1
Agilandeswari Devarajan, M K Mohan Maruga Raja
Background: Rasam is a traditional South Indian food, prepared using tamarind juice as a base, with a variety of spices. Rasam, with all its ingredients medicinally claimed for various ailments, is a functional food. Systematic consumption of traditional functional food provides an excellent preventive measure to ward off many diseases. Objective: To study rasam for cytotoxic, antimitotic, and antiproliferation potential beyond its culinary and nutritional effect...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29113957/ecological-observations-and-altered-indigenous-harvesting-practices-of-trillium-govanianum-melanthiaceae-in-indian-himalayas
#2
Harsh K Chauhan, Anil K Bisht, Indra D Bhatt, Arvind Bhatt, David Gallacher, Andrea Santo
ETHANOBOTANICAL RELEVANCE: Trillium govanianum Wall. ex D. Don (Melanthiaceae) is a high value medicinal herb which is used in both Indian and Chinese traditional medicines for various purposes such as treatment of cancer, hypertension, neurasthenia, giddiness, arthritis, dysentery, inflammation, sepsis and reproductive disorders. This species is restricted to specific habitat types, such as shaded, cold, moist habitats. However, the rhizomes of this species which are collected from wild populations have been traded throughout the Himalayan region and recently emerged as a significant source of income among local people of Indian Himalayan region...
November 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29109061/extraction-fractionation-and-re-fractionation-of-artemisia-nilagirica-for-anticancer-activity-and-hplc-esi-qtof-ms-ms-determination
#3
Neha Sahu, Sanjeev Meena, Vijaya Shukla, Priyank Chaturvedi, Brijesh Kumar, Dipak Datta, K R Arya
ETHNOPHARMACOLOGICAL RELEVANCE: Medicinal plants used in traditional medicines are affordable, easily accessible, safer, less toxic and considered as a rich or efficient source of bioactive molecules for modern therapeutics. Artemisia nilagirica (AR) has a long history of use in Indian traditional medicine to combat a wide variety of diseases including cancer. AIM OF THE STUDY: Considering the vast potential of traditional healing plants to deliver safer, less toxic and efficient chemotherapeutics, we have examined anticancer activity of ethanolic extract, bioactive fractions and sub-fractions of AR against different human cancer cell lines along with their phytochemical analysis to understand the insights of novel anticancer activities for further preclinical studies...
November 3, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29089186/how-to-plan-and-write-a-budget-for-research-grant-proposal
#4
REVIEW
Satish G Patil
Medical research can have an enormous positive impact on human health. Health research improves the quality of human lives and society which plays a vital role in social and economic development of the nation. Financial support is crucial for research. However, winning a research grant is a difficult task. A successful grant-winning application requires two key elements: one is an innovative research problem with best probable idea/plan for tackling it and appropriate planning of budget. The aim of the present paper is to give an insight on funding agencies providing funding for health research including traditional Indian medicine (from an Indian perspective) and key points for planning and writing budget section of a grant application...
October 28, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29071175/phytochemical-profile-aldose-reductase-inhibitory-and-antioxidant-activities-of-indian-traditional-medicinal-coccinia-grandis-l-fruit-extract
#5
Dasharath Kondhare, Harshad Lade
Coccinia grandis (L.) fruits (CGFs) are commonly used for culinary purposes and has several therapeutic applications in the Southeast Asia. The aim of this work was to evaluate phytochemical profile, aldose reductase inhibitory (ARI), and antioxidant activities of CGF extract. The CGFs were extracted with different solvents including petroleum ether, dichloromethane, acetone, methanol, and water. The highest yield of total extractable compounds (34.82%) and phenolic content (11.7 ± 0.43 mg of GAE/g dried extract) was found in methanol extract, whereas water extract showed the maximum content of total flavonoids (82...
December 2017: 3 Biotech
https://www.readbyqxmd.com/read/29057840/ethnomedicinal-phytochemical-and-ethnopharmacological-aspects-of-four-medicinal-plants-of-malvaceae-used-in-indian-traditional-medicines-a-review
#6
REVIEW
Jasmeet Kaur Abat, Sanjay Kumar, Aparajita Mohanty
The ethnomedicinal values of plants form the basis of the herbal drug industry. India has contributed its knowledge of traditional system medicines (Ayurveda and Siddha) to develop herbal medicines with negligible side effects. The World Health Organization has also recognized the benefits of drugs developed from natural products. Abutilon indicum, Hibiscus sabdariffa, Sida acuta and Sida rhombifolia are ethnomedicinal plants of Malvaceae, commonly used in Indian traditional system of medicines. Traditionally these plants were used in the form of extracts/powder/paste by tribal populations of India for treating common ailments like cough and cold, fever, stomach, kidney and liver disorders, pains, inflammations, wounds, etc...
October 18, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/29032054/role-of-ethanolic-extract-of-bacopa-monnieri-against-1-methyl-4-phenyl-1-2-3-6-tetrahydropyridine-mptp-induced-mice-model-via-inhibition-of-apoptotic-pathways-of-dopaminergic-neurons
#7
Babita Singh, Shivani Pandey, Satyndra Kumar Yadav, Rajesh Verma, Surya Pratap Singh, Abbas Ali Mahdi
Parkinson's disease (PD) is a neurodegenerative disease which causes rigidity, resting tremor and postural instability. The neuroprotective effects of an ethanolic extract of Bacopa monnieri (BM) were evaluated in a Parkinsonian mice model induced by the MPTP. The present study investigates the mechanisms of neuroprotection elicited by BM, an herb traditionally recognized by the Indian system of medicine, Ayurveda. An ethanolic extract of BM was co-treated with the MPTP induced mouse model of PD and was shown to significantly rescue the motor behaviour (Rotarod, Grip Strength and Foot Printing test)...
October 12, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28990045/anti%C3%A2-tumor-effects-of-bakuchiol-on-human-gastric-carcinoma-cell-lines-are-mediated-through-pi3k-akt-and-mapk-signaling-pathways
#8
Long Lv, Bo Liu
Bakuchiol is extracted from Psoralea corylifolia, a member of the Leguminosae family, has been used in Indian Ayurvedic and Chinese traditional medicine, and it possesses an anticancer effect. The primary aim of the present study was to identify the molecular mechanisms underlying the anticancer effect of bakuchiol monoterpenes. Bakuchiol treatment significantly inhibited NUGC3 human gastric cancer cell viability in a concentration dependent manner. In addition, bakuchiol significantly increased the apoptotic cell population in the sub‑G1 phase, and Annexin‑V‑fluorescein isothiocyanate/propidium iodide double staining confirmed the increase in apoptosis...
December 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28989243/a-comprehensive-review-on-rasam-a-south-indian-traditional-functional-food
#9
REVIEW
Agilandeswari Devarajan, M K Mohanmarugaraja
The view that food can have an expanded role that goes well beyond providing a source of nutrients truly applies to traditional functional foods. The systematic consumption of such traditional functional food provides an excellent preventive measure to ward off many diseases. Rasam, a soup of spices, is a traditional South Indian food. It is traditionally prepared using tamarind juice as a base, with the addition of Indian sesame oil, turmeric, tomato, chili pepper, pepper, garlic, cumin, curry leaves, mustard, coriander, asafoetida, sea salt, and water...
July 2017: Pharmacognosy Reviews
https://www.readbyqxmd.com/read/28988684/a-potent-nutraceutical-combination-of-cinnamomum-cassia-nigella-sativa-for-type-1-diabetes-mellitus
#10
Ginpreet Kaur, Mihir Invally, Mohammed Kamil Khan, Priyanka Jadhav
BACKGROUND: Nigella sativa (black cumin) and Cinnamomum cassia (Cinnamon) are an integral part of the Indian diet, and have also been sourced in the ayurveda, the traditional Indian system of medicine, for their medicinal properties. Both the herbs individually have been successfully evaluated for their preliminary antidiabetic potential. AIM: Herein, we dived deeper into antidiabetic properties of these herbs, by investigating the combinatorial effect of both herbs, on parameters of diabetes and further, as an adjunct to metformin therapy, for assessing the pharmacodynamics of herb-drug interaction in diabetes mellitus...
October 5, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28987943/a-standardized-extract-of-butea-monosperma-lam-flowers-suppresses-the-il-1%C3%AE-induced-expression-of-il-6-and-matrix-metalloproteases-by-activating-autophagy-in-human-osteoarthritis-chondrocytes
#11
Mohammad Y Ansari, Nazir M Khan, Tariq M Haqqi
BACKGROUND/OBJECTIVE: Osteoarthritis (OA) is a leading cause of joint dysfunction, disability and poor quality of life in the affected population. The underlying mechanism of joint dysfunction involves increased oxidative stress, inflammation, high levels of cartilage extracellular matrix degrading proteases and decline in autophagy-a mechanism of cellular defense. There is no disease modifying therapies currently available for OA. Different parts of the Butea monosperma (Lam.) plant have widely been used in the traditional Indian Ayurvedic medicine system for the treatment of various human diseases including inflammatory conditions...
October 4, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28940309/-it-felt-like-violence-indigenous-knowledge-traditions-and-the-postcolonial-ethics-of-academic-inquiry-and-community-engagement
#12
Joseph P Gone
In a 2014 presentation at an academic conference featuring an American Indian community audience, I critically engaged the assumptions and commitments of Indigenous Research Methodologies. These methodologies have been described as approaches and procedures for conducting research that stem from long-subjugated Indigenous epistemologies (or "ways of knowing"). In my presentation, I described a Crow Indian religious tradition known as a skull medicine as an example of an indigenous way of knowing, referring to a historical photograph of a skull medicine bundle depicted on an accompanying slide...
September 20, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/28939021/terminalia-arjuna-bark-extract-attenuates-picrotoxin-induced-behavioral-changes-by-activation-of-serotonergic-dopaminergic-gabaergic-and-antioxidant-systems
#13
Y Chandra Sekhar, G Phani Kumar, K R Anilakumar
Stress and emotion are associated with several illnesses from headaches to heart diseases and immune deficiencies to central nervous system. Terminalia arjuna has been referred as traditional Indian medicine for several ailments. The present study aimed to elucidate the effect of T. arjuna bark extract (TA) against picrotoxin-induced anxiety. Forty two male Balb/c mice were randomly divided into six experimental groups (n = 7): control, diazepam (1.5 mg·kg(-1)), picrotoxin (1 mg·kg(-1)) and three TA treatemt groups (25, 50, and 100 mg/kg)...
August 2017: Chinese Journal of Natural Medicines
https://www.readbyqxmd.com/read/28922612/analysis-of-levodopa-content-in-commercial-mucuna-pruriens-products-using-high-performance-liquid-chromatography-with-fluorescence-detection
#14
Amala Soumyanath, Tanya Denne, Amie Hiller, Shaila Ramachandran, Lynne Shinto
OBJECTIVES: Mucuna pruriens (MP) seeds contain levodopa (up to 2% by weight) and have been used in traditional Indian medicine to treat an illness named "Kampavata," now understood to be Parkinson's disease (PD). Studies have shown MP to be beneficial, and even superior, to levodopa alone in treating PD symptoms. Commercial products containing MP are readily available from online and retail sources to patients and physicians. Products often contain extracts of MP seeds, with significantly higher levodopa content than the seeds...
September 18, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28921713/chebulinic-acid-isolated-from-the-fruits-of-terminalia-chebula-specifically-induces-apoptosis-in-acute-myeloid-leukemia-cells
#15
Stuti Chhabra, Tripti Mishra, Yogesh Kumar, Gatha Thacker, Sanjeev Kanojiya, Naibedya Chattopadhyay, Tadigoppula Narender, Arun Kumar Trivedi
Chebulinic acid, an ellagitannin found in the fruits of Terminalia chebula, has been extensively used in traditional Indian system of medicine. It has shown to have various biological activities including antitumor activity. The present study aims to investigate the cytotoxic potential of chebulinic acid in human myeloid leukemia cells. Interestingly, chebulinic acid caused apoptosis of acute promyelocytic leukemia HL-60 and NB4 cells but not K562 cells. In vitro antitumor effects of chebulinic acid were investigated by using various acute myeloid leukemia cell lines...
September 18, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28914436/chinese-and-indian-women-s-experience-with-alternative-medications-for-menopause-related-symptoms-a-qualitative-analysis
#16
Saw Ohn Mar, Fatehpal Singh Malhi, Syed Hamid Syed Rahim, Myint Myint Soe
OBJECTIVE: To explore women's rationalization for using alternative medications, their experience and view on safety of long-term use. METHODS: Two focus group discussions, involving 5 participants each for Chinese and Indian groups, were conducted separately. Participant's personal information was collected anonymously. The discussion covered 5 areas: determinants for taking medications; reason for choosing alternative medications rather than hormone replacement therapy (HRT); how these medications help them; their view on cost-effectiveness and concerns over long-term use...
September 15, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28899496/neem-azadirachta-indica-an-indian-traditional-panacea-with-modern-molecular-basis
#17
REVIEW
Subash Chandra Gupta, Sahdeo Prasad, Amit K Tyagi, Ajaikumar B Kunnumakkara, Bharat B Aggarwal
BACKGROUND: For centuries, agents derived from natural sources (mother nature), especially plants have been the primary source of medicine. Neem, also referred to as Azadirachta indica is one such plant that has been so named because it provides freedom from all diseases, and used for thousands of years in Indian and African continents. Different parts of the plant including flowers, leaves, seeds and bark have been used to treat both acute and chronic human diseases; and used as insecticide; antimicrobial, larvicidal, antimalarial, antibacterial, antiviral, and spermicidal...
October 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28876177/ancient-indian-concepts-about-phenomenology-biology-and-therapeutics-of-epilepsy
#18
Ravindra Arya
This article discusses etiology, pathogenesis, symptoms, and treatment of epilepsy, as described in Charaka Samhitā (translation: Charaka's Compendium) and Sushruta Samhitā, the two core texts of Ayurveda, an ancient system of medicine. Ayurveda emphasized amnesia and loss of consciousness as core features of epileptic seizures (Sanskrit: apasmar; translation: apa negation, smaran memory) and recognized that seizures occur due to a disturbance in brain function or flow of "humors" to the brain. Semiology of various seizure types was well described...
September 6, 2017: Journal of the History of the Neurosciences
https://www.readbyqxmd.com/read/28875835/the-biological-potentialsof-indian-traditional-medicine-curcumin-for-treating-human-diseases
#19
C S Sumathi
Curcumin is an active compound extracted from the rhizomes of Curcuma longa L. (Turmeric). It possesses a di phenolic structure and there are three important fractions of curcumin namely curcumin, mono-desmethoxycurcumin and bis-desmethoxycurcumin. Curcumin is having high medicinal value. It is widely in Ayurveda, Siddha and Unani medicine formulations to treat various diseases. It is effective against microbial pathogens like bacteria, virus and fungi. It is highly potent and kills cancerous cells. Curcumin exhibits antioxidant activity and reduces lipoperoxidation...
August 30, 2017: Cardiovascular & Hematological Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/28867893/incubating-integrative-medicine-in-india-through-pmo-s-atal-incubator-scheme-of-niti-aayog
#20
EDITORIAL
Akshay Anand, Rahul Tyagi, Paramvir Kaur
BACKGROUND: Incubation centers are considered important tools to advance in a field of activity with multidisciplinary approach. The idea of incubation emerged long time back but it is actively pursued by funding agencies as a medium to propel community development. India's fast developing economy had limited tryst with Integrative Medicine until Indian Prime Minister, Narendra Modi, role modelled for Yoga in Chandigarh on the occasion of International Yoga Day. Integrative Medicine is a growing field and widely accepted as a cost-effective problem solving method that simplifies the management of incurable and complex disorders where modern medicine has little to offer...
July 2017: Annals of Neurosciences
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