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https://www.readbyqxmd.com/read/28717613/morphometric-evaluation-of-human-tendocalcaneus-a-cadaveric-study-of-south-indian-male-population
#1
Naveen Kumar, Ashwini P Aithal, Satheesha B Nayak, Jyothsna Patil, Abhinitha Padavinangadi, Biswa Bina Ray
INTRODUCTION: Tendocalcaneus or Achilles tendon is formed by the fusion of the tendons of gastrocnemius and soleus muscles. Normal morphometric measurements of tendo-calcaneus serves an important landmark in its anthropometric evaluation and biomechanical characteristics. Hence the objective of this study was to provide detailed morphometric profile of tendocalcaneus in south indian cadaveric male population. MATERIALS AND METHOD: A total of 64 dissected adult limbs was studied...
January 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28704160/assessment-of-tribal-bison-worker-hazards-using-trusted-research-facilitators
#2
Ellen Duysen, Kelsey Irvine, Aaron Yoder, Christina Topliff, Clayton Kelling, Shireen Rajaram
OBJECTIVES: Agriculture is one of the most hazardous industries in the United States. Within agriculture, livestock handling is particularly dangerous. While injury and fatality rates for bison handlers have not been reported, workers in many of the newly established tribal bison herds have limited safety training and animal handling experience, making this a vulnerable workforce. Veterinarians and herd managers, working with tribal bison herds, recognized the need for improvement in the working environment and for worker safety training...
July 13, 2017: Journal of Agromedicine
https://www.readbyqxmd.com/read/28697403/ameliorative-efficacy-of-bioencapsulated-chironomous-larvae-with-shilajit-on-zebrafish-danio-rerio-exposed-to-ionizing-radiation
#3
M Saiyad Musthafa, A Athaullah, S Anbumani, A Jawahar Ali, Mehrajuddin War, Bilal Ahmad Paray, Mohammad K Al-Sadoon, S S Muthiah, Palani Kembeeram, R Harikrishnan
Using Zebrafish (Danio rerio) as a model organism, we evaluated the radioprotective and antioxidant effects of the Indian traditional medicine Shilajit exposed to X-Ray. The Zebrafish were divided into three experimental groups and control group, each group containing ten fish. The three experimental fish groups, group I, group II and group III were fed with 3, 5 and 7ppm shilajit encapsulated Chironomous larvae and group IV served as a control fed with non- encapsulated larvae. After 60 days of feeding trial, fish were irradiated with X-Ray at a single acute dose of 1Gy...
July 5, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28694686/molecular-docking-qsar-and-admet-studies-of-withanolide-analogs-against-breast-cancer
#4
Dharmendra K Yadav, Surendra Kumar, Saloni, Harpreet Singh, Mi-Hyun Kim, Praveen Sharma, Sanjeev Misra, Feroz Khan
Withanolides are a group of pharmacologically active compounds present in most prodigal amounts in roots and leaves of Withania somnifera (Indian ginseng), one of the most important medicinal plants of Indian traditional practice of medicine. Withanolides are steroidal lactones (highly oxygenated C-28 phytochemicals) and have been reported to exhibit immunomodulatory, anticancer and other activities. In the present study, a quantitative structure activity relationship (QSAR) model was developed by a forward stepwise multiple linear regression method to predict the activity of withanolide analogs against human breast cancer...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28688542/evaluation-of-apoptotic-activity-of-withania-coagulans-methanolic-extract-against-human-breast-cancer-and-vero-cell-lines
#5
Rumana Ahmad, Afreen Fatima, A N Srivastava, Mohsin Ali Khan
BACKGROUND: The genus Withania (Family: Solanaceae) holds an important position in Ayurveda, the Indian traditional system of medicine. Withania somnifera Dunal and Withania coagulans Dunal have been documented in folklore as panaceas for various ailments since time immemorial. W. coagulans (WC), commonly called as Indian cheese maker is used for fermenting milk for cheese production in various parts of India. OBJECTIVES: In the study, in vitro cytotoxicity of methanolic extract of dried fruits (berries) of WC was evaluated in a dose dependent manner using trypan blue dye exclusion method against human breast cancer cell line MDA-MB-231 and normal kidney epithelial cell line Vero in the range 20-200 μg/ml...
July 6, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/28685479/neoteric-trends-in-tissue-culture-mediated-biotechnology-of-indian-ipecac-tylophora-indica-burm-f-merrill
#6
REVIEW
Saikat Gantait, Suprabuddha Kundu
Tylophora indica (Burm. f.) Merrill, an ethno-pharmacologically important perennial climber of Asclepiadaceae, is commonly known as Antamul or Indian ipecac. It is essentially accredited for its medicinal properties owing to its wide range of alkaloids in the form of bioactive secondary metabolites, such as tylophorine, tylophorinine, and tylophorinidine. Accelerated mass propagation of Tylophora is challenging because of its reduced seed germination frequency that consequently headed the pursuit for efficient protocols on in vitro propagation for the large-scale regeneration, conservation as well as sustainable supply of quality propagules...
July 2017: 3 Biotech
https://www.readbyqxmd.com/read/28681754/microsurgical-anatomy-of-the-superior-sagittal-sinus-and-draining-veins
#7
Mariano Anto Bruno-Mascarenhas, Vengalathur G Ramesh, Sundar Venkatraman, Jolarpettai V Mahendran, S Sundaram
BACKGROUND: The superior sagittal sinus and the draining cerebral veins are often encountered during the surgery for parasagittal and falx meningiomas and during the interhemisperic transcallosal approaches. A knowledge about the variations from the normally described anatomy helps in anticipating and avoiding problems related to these structures during surgery. AIM: The normal variations in the disposition of the superior sagittal sinus and the number and direction of the draining veins in the Indian population have been studied...
July 2017: Neurology India
https://www.readbyqxmd.com/read/28675857/anti-colon-cancer-activity-of-murraya-koenigii-leaves-is-due-to-constituent-murrayazoline-and-o-methylmurrayamine-a-induced-mtor-akt-downregulation-and-mitochondrial-apoptosis
#8
Ashutosh Arun, Om P S Patel, Deepika Saini, Prem P Yadav, Rituraj Konwar
In recent years, many alkaloids of plant origin have attracted great attention due to their diverse range of biological properties including anti-hyperglycemic, anti-oxidant, anti-inflammatory, anti-diabetic and anti-tumor activity. Herein, the pyranocarbazole alkaloids were isolated from leaves of Murraya koenigii and their anti-cancer potential was investigated in different cancer cell lines. Among all tested compounds, murrayazoline and O-methylmurrayamine A demonstrated potent anti-cancer activity against DLD-1 colon cancer cells with the IC50 values of 5...
July 1, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28671029/chemopreventive-effect-of-syringic-acid-on-7-12-dimethylbenz-a-anthracene-induced-hamster-buccal-pouch-carcinogenesis
#9
Velu Periyannan, Veerasamy Vinothkumar, Sukumar Babukumar, Ramachandhiran Duraisamy
Oral squamous cell carcinoma is most prevalent and refractory cancers worldwide. Recently chemoprevention could be a promising approach in developing countries. The present study investigates the mechanism of syringic acid (SA), a phenolic constituent of plant Alpiniacalcarata Roscoe the leaves used, traditional Indian Ayurveda medicines, mediated chemoprevention on 7,12-dimethylbenz(a)anthracene (DMBA) induced hamster buccal pouch carcinogenesis (HBPC). Lipid peroxidation and antioxidants were measured in the plasma and buccal tissues in experimental hamsters...
July 3, 2017: Toxicology Mechanisms and Methods
https://www.readbyqxmd.com/read/28670545/gestational-weight-gain-and-pregnancy-outcomes-in-relation-to-body-mass-index-in-asian-indian-women
#10
Balaji Bhavadharini, Ranjit Mohan Anjana, Mohan Deepa, Gopal Jayashree, Subramanyam Nrutya, Mahadevan Shobana, Belma Malanda, Arivudainambi Kayal, Anne Belton, Kurian Joseph, Kurian Rekha, Ram Uma, Viswanathan Mohan
AIM: The aim of the study was to compare the weight gain during pregnancy (using Institute of Medicine guidelines) among Asian Indians across different body mass index (BMI) categories (using World Health Organization Asia Pacific BMI cut points) and to compare the pregnancy outcomes in each of the different BMI categories. METHODOLOGY: Retrospective records of 2728 pregnant women attending antenatal clinics and private maternity centers in Chennai, South India, from January 2011 to January 2014 were studied...
July 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28670212/native-voices-native-peoples-concepts-of-health-and-illness-in-new-mexico-opening-a-local-conversation-by-hosting-a-national-traveling-exhibit
#11
Patricia V Bradley, Laura J Hall, Gale G Hannigan, Frederick B Wood
BACKGROUND: The University of New Mexico Health Sciences Library and Informatics Center hosted the National Library of Medicine's Native Voices: Native Peoples' Concepts of Health and Illness traveling exhibit. The authors' goal was to promote local interest in the Native Voices exhibit, with an emphasis on making the exhibit content and materials available to American Indian communities throughout rural New Mexico. CASE PRESENTATION: We convened a daylong summit to highlight the exhibit and encourage discussion among 30 American Indian community health educators...
July 2017: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/28669236/differences-in-nativity-age-and-gender-may-impact-health-behavior-and-perspectives-among-asian-indians
#12
Sohini Dhar, Beverly Gor, Deborah Banerjee, Sunil Krishnan, V K Dorai, Lovell Jones, Kanchan Kabad, Lakshmi Rai Naik, Sewa S Legha, Mala Pande
OBJECTIVE: Identify health perspectives among Asian Indians in greater Houston area, to guide a tailored community wide survey. DESIGN: Four focus groups of different ages, gender, and nativity were conducted at which participants were asked for their opinions about specific health topics. Key informant interviews were conducted with ten community leaders to validate focus group responses. Recordings from focus groups and key informant interviews were transcribed and analyzed...
July 3, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28668659/morbidity-and-mortality-amongst-indian-hajj-pilgrims-a-3-year-experience-of-indian-hajj-medical-mission-in-mass-gathering-medicine
#13
Inam D Khan, Shahbaz A Khan, Bushra Asima, Syed B Hussaini, M Zakiuddin, F A Faisal
The Hajj, a mass-gathering of over 3.5-million pilgrims, faces challenges to global health-security, housing, food, water, transportation, communication, sanitation, crowd-control and security. The Indian Medical Mission extended health-security to approximately 140,000 pilgrims, through outreach medical teams, primary-care clinics, tent-clinics, secondary-care hospitals and evacuation capabilities. Data on medical attendance, bed-occupancy, investigations, referrals, medication usage and deaths was compared...
June 28, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28664142/molecular-mechanisms-of-anticancer-activity-of-deoxyelephantopin-in-cancer-cells
#14
Farha Arakkaveettil Kabeer, Dhanya Sethumadhavan Rajalekshmi, Mangalam Sivasankaran Nair, Remani Prathapan
BACKGROUND: Deoxyelephantopin (DOE) is a natural bioactive sesquiterpene lactone from Elephantopus scaber, a traditionally relevant herb in Chinese and Indian medicine. It has shown promising anticancer effects against a broad spectrum of cancers. METHODS: We examined the effect of DOE on growth, autophagy, apoptosis, cell cycle progression, metastasis, and various molecular signaling pathways in cancer cells, and endeavored to decipher the molecular mechanisms underlying its effect...
June 2017: Integrative medicine research
https://www.readbyqxmd.com/read/28664134/traditional-indian-medicine-tim-and-traditional-korean-medicine-tkm-aconstitutional-based-concept-and-comparison
#15
REVIEW
Young Min Kang, Richard Komakech, Chandrakant Shivappa Karigar, Asma Saqib
Traditional and complementary medicine (T&CM) plays an integral role in providing health care worldwide. It is based on sound fundamental principles and centuries of practices. This study compared traditional Indian medicine (TIM) and traditional Korean medicine (TKM) basing on data obtained from peer reviewed articles, respective government institutional reports and World Health Organization reports. Despite the fact that TIM and TKM have individual qualities that are unique from each other including different histories of origin, they share a lot in common...
June 2017: Integrative medicine research
https://www.readbyqxmd.com/read/28663722/bacoside-a-induces-tumor-cell-death-in-human-glioblastoma-cell-lines-through-catastrophic-macropinocytosis
#16
Sebastian John, K C Sivakumar, Rashmi Mishra
Glioblastoma multiforme (GBM) is a highly aggressive type of brain tumor with an extremely poor prognosis. Recent evidences have shown that the "biomechanical imbalances" induced in GBM patient-derived glioblastoma cells (GC) and in vivo via the administration of synthetic small molecules, may effectively inhibit disease progression and prolong survival of GBM animal models. This novel concept associated with de novo anti-GBM drug development has however suffered obstacles in adequate clinical utility due to the appearance of unrelated toxicity in the prolonged therapeutic windows...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/28658860/muscle-activation-profiles-and-co-activation-of-quadriceps-and-hamstring-muscles-around-knee-joint-in-indian-primary-osteoarthritis-knee-patients
#17
Sanjeev Kumar Sharma, Shiv Lal Yadav, U Singh, Sanjay Wadhwa
INTRODUCTION: Osteoarthritis (OA) of knee is a common joint disease. It is associated with reduced knee joint stability due to impaired quadriceps strength, pain, and an altered joint structure. There is altered muscle activation in knee OA patients, which interferes with normal load distribution around the knee and facilitates disease progression. AIM: Our primary aim was to determine activation patterns of the muscles i.e., quadriceps and hamstrings in knee OA patients during walking...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28650892/the-2017-hormone-therapy-position-statement-of-the-north-american-menopause-society
#18
(no author information available yet)
The 2017 Hormone Therapy Position Statement of The North American Menopause Society (NAMS) updates the 2012 Hormone Therapy Position Statement of The North American Menopause Society and identifies future research needs. An Advisory Panel of clinicians and researchers expert in the field of women's health and menopause was recruited by NAMS to review the 2012 Position Statement, evaluate new literature, assess the evidence, and reach consensus on recommendations, using the level of evidence to identify the strength of recommendations and the quality of the evidence...
June 22, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28650869/the-2017-hormone-therapy-position-statement-of-the-north-american-menopause-society
#19
(no author information available yet)
The 2017 Hormone Therapy Position Statement of The North American Menopause Society (NAMS) updates the 2012 Hormone Therapy Position Statement of The North American Menopause Society and identifies future research needs. An Advisory Panel of clinicians and researchers expert in the field of women's health and menopause was recruited by NAMS to review the 2012 Position Statement, evaluate new literature, assess the evidence, and reach consensus on recommendations, using the level of evidence to identify the strength of recommendations and the quality of the evidence...
July 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28646808/traditional-uyghur-medicine-concepts-historical-perspective-and-modernization
#20
Adelijang Wusiman, Saifuding Abula, Mikeremu Shayibuzhati, Xiaoying Zhang
Context • Traditional Uyghur medicine (TUM) is rooted in ancient Uyghur medical theory that was developed with the combined essence of different traditional medicines, such as Han Chinese, Egyptian, ancient Greek, Arabian, Persian, and Indian medicines. Modern experimental methods and technologies for disease diagnoses have accelerated the modernization of Uyghur medicine. Objective • The research team intended to compile a comprehensive introduction to TUM and to determine the current state of research in the field to establish a basis for future modernization of Uygur medicine...
June 23, 2017: Alternative Therapies in Health and Medicine
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