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https://www.readbyqxmd.com/read/28548625/acute-procedural-outcomes-of-orbital-atherectomy-for-the-treatment-of-common-femoral-artery-disease-sub-analysis-of-the-confirm-registries
#1
Michael S Lee, Daniel Heikali, Jihad Mustapha, George Adams, Ehtisham Mahmud
This analysis compared the angiographic outcomes of patients treated with orbital atherectomy for calcified common femoral artery (CFA) and superficial femoral artery (SFA) disease. The ideal revascularization strategy for CFA disease is unknown. Endarterectomy has been considered the standard of care for CFA disease for over 50 years. Endovascular intervention is becoming more commonly used to revascularize the CFA given the advances in technology and the less invasive nature of the procedure. Patient demographics, lesion characteristics, and procedure data for all CONFIRM patients with at least one CFA lesion location ( n=147 patients; n=200 lesions) were compared to patients with at least one SFA lesion location ( n=1508 patients; n=2367 lesions)...
May 1, 2017: Vascular Medicine
https://www.readbyqxmd.com/read/28548623/pneumocystis-carinii-infection-with-severe-pneumomediastinum-and-lymph-node-involvement-in-a-whippet-mixed-breed-dog
#2
Christiane Weissenbacher-Lang, Andrea Fuchs-Baumgartinger, Andrea Klang, Sibylle Kneissl, Armin Pirker, Sarina Shibly, Stephanie von Ritgen, Herbert Weissenböck, Frank Künzel
A 3.5-y-old Whippet mixed-breed dog was presented with a history of respiratory distress, exercise intolerance, and generalized demodicosis. Hematologic alterations included marked leukocytosis and neutrophilia. Radiographic examination showed a diffuse interstitial and mild peripheral alveolar lung pattern and pneumomediastinum. Because the cytologic examination of the bronchoalveolar aspirate was not diagnostic and a persistent perforation of the upper respiratory tract could not be ruled out, the dog was submitted to thoracoscopy, and subsequently the left cranial lung lobe as well as mediastinal and sternal lymph nodes were resected...
May 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28548239/impact-of-barium-enema-on-acute-diverticulitis-recurrence-a-retrospective-cohort-study-of-349-patients
#3
Francisco J Medina-Fernández, Lidia Rodríguez-Ortiz, Dimas J Garcilazo-Arismendi, Elena Navarro-Rodríguez, Eva M Torres-Tordera, César A Díaz-López, Javier Briceño
AIM: Acute diverticulitis is becoming a health concern in western countries as its incidence is increasing. Currently, one of the accepted theories on possible causes of diverticular perforation is the impactation of faecal residuals into some diverticula. Our aim was to evaluate whether barium impactation might have a negative effect by promoting diverticular inflammation/rupture and thereby acute diverticulitis recurrence. METHODS: A retrospective cohort study (January 2005/December 2015) was conducted at the Reina Sofia University Hospital of Cordoba (Spain)...
May 26, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28547758/ghrelin-receptors-mediate-ghrelin-induced-excitation-of-agrp-npy-but-not-pomc-neurons
#4
Shao-Rui Chen, Hong Chen, Jing-Jing Zhou, Geetali Pradhan, Yuxiang Sun, Hui-Lin Pan, De-Pei Li
Ghrelin increases food intake and body weight by stimulating orexigenic AgRP/NPY neurons and inhibiting anoexic POMC neurons in the hypothalamus. Growth hormone secretagogue receptor (Ghsr) mediates the effect of ghrelin on feeding behavior and energy homeostasis. However, the role of Ghsr in the ghrelin effect on these two populations of neurons is unclear. We hypothesized that Ghsr mediates the effect of ghrelin on AgRP and POMC neurons. In this study, we determined whether Ghsr similarly mediates the effects of ghrelin on AgRP/NPY and POMC neurons using cell type-specific Ghsr-knockout mice...
May 26, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28547527/weakened-intracellular-zn-2-buffering-in-the-aged-dentate-gyrus-and-its-involvement-in-erasure-of-maintained-ltp
#5
Atsushi Takeda, Haruna Tamano, Taku Murakami, Hiroyuki Nakada, Tatsuya Minamino, Yuta Koike
Memory is lost by the increased influx of extracellular Zn(2+) into neurons. It is possible that intracellular Zn(2+) dynamics is modified even at non-zincergic medial perforant pathway-dentate granule cell synapses along with aging and that vulnerability to the modification is linked to age-related cognitive decline. To examine these possibilities, vulnerability of long-term potentiation (LTP) maintenance, which underlies memory retention, to modification of synaptic Zn(2+) dynamics was compared between young and aged rats...
May 25, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28546722/malignant-peripheral-nerve-sheath-tumour-of-the-small-bowel-presenting-with-intussusception-and-perforation-a-double-jeopardy
#6
Ananth P Abraham, Joshua Franklyn, Jagan Chandramohan, Pranay Gaikwad, John C Muthusami
Malignant peripheral nerve sheath tumours (MPNST) are rare soft tissue sarcomas which largely occur in the extremities and the head and neck region. The tumours are aggressive with a high rate of recurrence. Radical surgical resection remains the treatment of choice with adjuvant radiation therapy and chemotherapy still failing to demonstrate a clear benefit. The gastrointestinal tract is an exceedingly rare site for these tumours. We report an unusual case of a young male with an MPNST of the small bowel who presented with an ileocolic intussusception and sigmoid perforation...
June 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28546687/adjunctive-therapies-for-bacterial-keratitis
#7
Turki Abdulaziz Bin Dakhil, Donald U Stone, David C Gritz
Bacterial keratitis is the most common type among all types of infectious keratitis. Currently, antibiotics are the main-stay of treatment. The objective of this systematic review is to review published clinical studies which discuss the adjunctive treatment of bacterial keratitis to guide clinical decision-making. We reviewed the role of a variety of medications and surgeries which can help in managing bacterial keratitis complications, which include as thinning, perforation, and impaired wound healing. We have included appropriate animal and laboratory studies, case reports and case series, and randomized clinical trials regarding each therapy...
January 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/28545511/gastric-hepatoid-adenocarcinoma-resulting-in-a-spontaneous-gastric-perforation-a-case-report-and-review-of-the-literature
#8
Junichi Yoshizawa, Satoshi Ishizone, Meguru Ikeyama, Jun Nakayama
BACKGROUND: Gastric hepatoid adenocarcinoma (GHAC) is an atypical form of gastric cancer (GC) that has similar tissue morphology to hepatocellular carcinoma and frequently produces alpha-fetoprotein. We present an exceedingly rare case of GHAC resulting in a spontaneous gastric perforation. CASE PRESENTATION: A 61-year-old man presented at our institution complaining of abdominal and back pain. A computed tomography scan revealed a spontaneous gastric perforation with a solitary liver tumor and lymph node swelling...
May 25, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28544511/computational-fluid-dynamics-evaluation-of-posterior-septectomy-as-a-viable-treatment-option-for-large-septal-perforations
#9
Bradley A Otto, Chengyu Li, Alexander A Farag, Benjamin Bush, Jillian P Krebs, Ryan D Hutcheson, Kanghyun Kim, Bhakthi Deshpande, Kai Zhao
BACKGROUND: Numerous surgical techniques exist to treat nasal septal perforation (NSP). The surgical closure of large NSPs (>2 cm) is still challenging. Posterior septectomy has been reported as a simple alternative to treat large NSP, yet its mechanisms for symptom relief are not clear, and if failed, its consequence cannot be easily reversed. METHODS: Ten NSP patients were recruited: 5 underwent posterior septectomy and 5 underwent conventional flap or button repair...
May 23, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28544131/sclerocorneal-graft-and-sequential-removal-of-melted-cornea-after-severe-corneal-burn-with-perforation
#10
Anja Viestenz, Berthold Seitz, Hans-Gert Struck, Arne Viestenz
INTRODUCTION: Corneal burn grade IV usually leads to blindness. Several different surgical techniques remain challenging owing to the extensive tissue damage. Here, we introduce a novel technique with a 15 mm corneoscleral and limbal homologous graft combined with sequential autologous corneal removal ab interno, with a vitrectomy probe to save the anterior chamber angle. In vivo anatomy with optical coherence tomography is the surgical key. METHOD: A large 15 mm sclerocorneal graft is sutured on top of the remainder of the destroyed cornea and sclera after removal of the epithelium and conjunctiva, with anterior synechiolysis if necessary, peripheral iridectomy and conjunctivoplasty...
May 22, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28542660/-trichomycosis-trichobacteriosis-capitis-in-an-infant-microbiological-dermoscopic-and-ultrastructural-features
#11
Alexandro Bonifaz, Ixchel Ramírez-Ricarte, Alejandra Rodríguez-Leviz, Marco A Hernández, Carlos Mena, Adriana Valencia
Trichomycosis is a superficial infection caused by Corynebacterium flavescens, which regularly affects axillary, and to a a lesser extent, pubic, scrotal and intergluteal, and exceptionally, head hairs or trichomycosis capitis (TC). This condition is characterised by the formation of bacterial nodules. Clinically, it can be confused with white piedra or pediculosis. The diagnosis is made by microscopic and dermoscopic observation and confirmed by culture. OBJECTIVE: To present a case of TC in an infant and illustrate the microscopic, dermoscopic, and ultrastructural characteristics...
April 2017: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/28540831/ninety-percent-of-the-adverse-outcomes-occur-in-ten-percent-of-patients-can-we-identify-the-populations-at-high-risk-of-developing-peritoneal-metastases-after-curative-surgery-for-colorectal-cancer
#12
Charles Honoré, Maximiliano Gelli, Julie Francoual, Léonor Benhaim, Dominique Elias, Diane Goéré
BACKGROUND: Peritoneal metastases (PM) occur in 3.4% to 6.3% after curative surgery for non-metastatic colorectal cancer. Systematic "2(nd) look" surgery help overcoming the diagnostic problem but can be only proposed to selected patients. The aim of this study was to update the knowledge on risk factors of developing PM after curative surgery for colorectal cancer. METHODS: A systematic review of the literature published between 2011 and 2016 was made, searching for all clinical studies reporting the incidence of recurrent PM after curative surgery for colorectal cancer and factors associated with the primary tumor that were likely to influence this recurrence rate...
March 29, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28540578/-complications-and-postoperative-therapeutic-strategies-in-cross-linking
#13
REVIEW
M Kohlhaas
CLINICAL ISSUE: The reduced corneal mechanical stability in keratoconus and similar collagen diseases can lead to a progressive and irregular corneal shape and decrease of visual acuity. DIAGNOSTICS: A progression of keratectatic diseases can be shown with corneal topography. TREATMENT: Keratoconus can be treated by photo-oxidative cross-linking of the corneal collagen. In order to achieve a high absorption of irradiation energy in the cornea, riboflavin at a concentration of 0...
May 24, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28540478/immune-checkpoint-inhibitor-induced-colitis-diagnosis-and-management
#14
REVIEW
Caroline Prieux-Klotz, Marie Dior, Diane Damotte, Johann Dreanic, Bertrand Brieau, Catherine Brezault, Vered Abitbol, Stanislas Chaussade, Romain Coriat
Immune checkpoint inhibitors are monoclonal antibodies indicated for an increasing number of malignant diseases. These agents can cause specific side effects, which need to be anticipated while clear patterns of management need to be established. Immune checkpoint inhibitor-mediated gastrointestinal side effects, including diarrhea and colitis, occur in up to 30% of patients. Severe colitis can lead to severe dehydration or intestinal perforation. Endoscopic lesions and histopathological features of immune checkpoint inhibitor-induced colitis are similar to an inflammatory bowel disease (IBD) flare...
May 24, 2017: Targeted Oncology
https://www.readbyqxmd.com/read/28540313/central-vascular-complications-following-elective-catheterization-using-transradial-percutaneous-coronary-intervention
#15
Julia Merkle, Christopher Hohmann, Anton Sabashnikov, Thorsten Wahlers, Jens Wippermann
Percutaneous coronary intervention is commonly used to treat coronary artery disease. Both transradial and transfemoral approaches are applied. In general, fewer complications are seen with the transradial approach compared to the transfemoral access, for which reason the transradial catheterization is frequently preferred. In this case presentation, we describe 2 cases of elective transradial coronary angiography both resulting in severe central vascular complications: perforation of the right subclavian artery with a mediastinal hematoma and dissection of the brachio-cephalic trunk and the aortic arch...
January 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28540188/ingested-foreign-body-causing-duodenal-and-colonic-perforations-in-a-child
#16
Dileep Garg, Aditya Pratap Singh, Sunil Kothari
Most ingested foreign bodies usually pass uneventfully through the gastrointestinal tract. Few may cause complications and require surgical interventions. We report a 1.5-year-old child who ingested hair clip and presented with vomiting and obstruction. At operation, we found duodenal and colonic perforations. Hair clip was removed with repair of perforations.
May 2017: APSP Journal of Case Reports
https://www.readbyqxmd.com/read/28540052/a-unique-case-of-massive-gastrointestinal-bleeding
#17
Akihiko Kida, Koichiro Matsuda, Mitsuru Matsuda, Akito Sakai, Yatsugi Noda
OBJECTIVES: Lipomas are the second most common benign tumors of the small bowel, and most lipomas are asymptomatic. However, lipomas with diameters of >20 mm tend to be symptomatic, for example, to cause bleeding, obstructive jaundice, abdominal pain, intestinal obstruction, intussusception, and/or perforation. METHODS/RESULTS: We report a case of massive gastrointestinal bleeding from a jejunal lipoma combined with intussusception. A preoperative diagnosis of gastrointestinal bleeding derived from a jejunal lipoma combined with intussusception was made based on double-balloon enteroscopy and contrast-enhanced computed tomography, and partial resection of the small intestine was performed...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28539570/usefulness-and-safety-of-a-novel-modification-of-the-retrograde-approach-for-the-long-tortuous-chronic-total-occlusion-of-coronary-arteries
#18
Zehan Huang, Bin Zhang, Weilu Chai, Dunliang Ma, Hongtao Liao, Zhian Zhong, Feng Wang, Jingye Lin
The aim of this study was to evaluate the feasibility and efficacy of the Guidezilla guide extension catheter in a reverse controlled antegrade and retrograde subintimal tracking (CART) technique for chronic total occlusion (CTO) recanalization.We retrospectively collected 80 CTO cases using reverse CART technology from January 2015 to October 2015 and 20 CTO cases using Guidezilla reverse-CART technology from October 2015 to March 2016. Guidezilla was applied in cases when it was difficult to advance a retro-guidewire through an occlusion segment into the antegrade guide catheter...
May 23, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28539211/left-ventricular-perforation-in-a-patient-with-a-left-ventricular-aneurysm-during-noga%C3%A2-catheter-mapping
#19
Gaurav K Sharma, Marie-France Poulin, Gary L Schaer
Endocardial mapping of the left ventricle (LV) using the NOGA® XP Cardiac Navigation System can identify chronically ischemic and viable myocardium in patients with coronary artery disease by generating electromechanical maps. These maps are very useful when targeting myocardial tissue for injection of stem cells. We present the case of a woman who developed a perforation at the site of an LV aneurysm during NOGA mapping prior to the transendocardial injection of stem cells, as part of a multicenter clinical trial...
May 13, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28539036/a-case-of-tuberculous-peritonitis-presenting-as-small-bowel-obstruction
#20
Hae Koo Kim, Sung Eun Kim, Moo In Park, Seun Ja Park, Won Moon, Jae Hyun Kim, Kyoungwon Jung, Yong Jin Nam
The peritoneum is one of the common extrapulmonary sites of tuberculosis infection. Patients with underlying end-stage renal or liver disease are frequently complicated by tuberculous peritonitis; however, the diagnosis of the tuberculous peritonitis is difficult due to its insidious nature, well as its variability in presentation and limitation of available diagnostic tests. Once diagnosed, the preferred treatment is usually antituberculous therapy in uncomplicated cases. However, surgical treatment may also be required for complicated cases, such as small bowel obstruction or perforation...
May 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
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