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https://www.readbyqxmd.com/read/28626628/assessing-fracture-risk-in-early-stage-breast-cancer-patients-treated-with-aromatase-inhibitors-an-enhanced-screening-approach-incorporating-trabecular-bone-score
#1
Veronica Mariotti, David B Page, Oksana Davydov, Didier Hans, Clifford A Hudis, Sujata Patil, Siddharth Kunte, Monica Girotra, Azeez Farooki, Monica N Fornier
INTRODUCTION: Aromatase-inhibitors (AIs) are commonly used for treatment of patients with hormone-receptor positive breast carcinoma, and are known to induce bone density loss and increase the risk of fractures. The current standard-of-care screening tool for fracture risk is bone mineral density (BMD) by dual-energy X-ray absorptiometry (DXA). The fracture risk assessment tool (FRAX®) may be used in conjunction with BMD to identify additional osteopenic patients at risk of fracture who may benefit from a bone-modifying agent (BMA)...
June 2017: Journal of Bone Oncology
https://www.readbyqxmd.com/read/28623228/half-of-salaried-and-locum-gps-are-stressed-bma-survey-finds
#2
Abi Rimmer
No abstract text is available yet for this article.
June 16, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28622184/does-age-influence-the-efficacy-of-demineralized-bone-matrix-enriched-with-concentrated-bone-marrow-aspirate-in-lumbar-fusions
#3
Remi M Ajiboye, Mark A Eckardt, Jason T Hamamoto, Akshay Sharma, Adam Z Khan, Jeffrey C Wang
STUDY DESIGN: Retrospective study. OBJECTIVE: Evaluate the effect of age on the efficacy of allograft/demineralized bone matrix (DBM) enriched with concentrated bone marrow aspirate (BMA) in posterolateral lumbar fusions (PLFs). SUMMARY OF BACKGROUND DATA: Cell-based therapies such as concentrated BMA have been developed as a potential alternative to iliac crest bone graft (ICBG). BMA contains mesenchymal stem cells (MSCs) and growth factors that can confer osteogenic and osteoinductive potential to osteoconductive scaffolds such as DBM/allograft...
June 15, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28612576/-clinical-feature-in-infants-of-breast-feeding-allergy-and-its-possible-relation-with-gastrointestinal-peptide-change-in-breast-milk
#4
Yong-Mei Xie, Shan Gao, Li-Yuan Wang, Zhi-Ling Wang, Xiao-Tang Cai, Hui Zhou
OBJECTIVES: To investigate clinical features in infants of breast milk allergy(BMA), and the possible relationship with the changes of somatostatin (SST) and motilin (MTL) in breast milk. METHODS: Twenty three cases of pure breast feeding infants with allergic gastroenteritis were collected, while another 23 normal infants with pure breast feeding were enrolled as normal controls. Samples of infant stools and breast milk were collected for the measurement of SST and MTL levels detected by by radioimmunity...
January 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28607559/bone-marrow-aspirate-concentrate-enhanced-marrow-stimulation-of-chondral-defects
#5
REVIEW
Henning Madry, Liang Gao, Hermann Eichler, Patrick Orth, Magali Cucchiarini
Mesenchymal stem cells (MSCs) from bone marrow play a critical role in osteochondral repair. A bone marrow clot forms within the cartilage defect either as a result of marrow stimulation or during the course of the spontaneous repair of osteochondral defects. Mobilized pluripotent MSCs from the subchondral bone migrate into the defect filled with the clot, differentiate into chondrocytes and osteoblasts, and form a repair tissue over time. The additional application of a bone marrow aspirate (BMA) to the procedure of marrow stimulation is thought to enhance cartilage repair as it may provide both an additional cell population capable of chondrogenesis and a source of growth factors stimulating cartilage repair...
2017: Stem Cells International
https://www.readbyqxmd.com/read/28564490/effect-of-comonomers-on-physical-properties-and-cell-attachment-to-silica-methacrylate-acrylate-hybrids-for-bone-substitution
#6
Justin J Chung, Brian S T Sum, Siwei Li, Molly M Stevens, Theoni K Georgiou, Julian R Jones
Hybrids with a silica network covalently bonded to a polymer are promising materials for bone repair. Previous work on synthesizing methyl methacrylate (MMA) based copolymers by reversible addition-fragmentation chain transfer (RAFT) polymerization gives high tailorability of mechanical properties since sophisticated polymer structures can be designed. However, more flexible hybrids would be beneficial. Here, n-butyl methacrylate (BMA) and methyl acrylate (MA) based hybrids are produced. Unlike MMA, BMA and MA hybrids do not show plastic deformation, and BMA hybrid has strain to failure of 33%...
May 31, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28539939/quantitative-assessment-of-optimal-bone-marrow-site-for-the-isolation-of-porcine-mesenchymal-stem-cells
#7
J S McDaniel, B Antebi, M Pilia, B J Hurtgen, S Belenkiy, C Necsoiu, L C Cancio, C R Rathbone, A I Batchinsky
Background. One of the most plentiful sources for MSCs is the bone marrow; however, it is unknown whether MSC yield differs among different bone marrow sites. In this study, we quantified cellular yield and evaluated resident MSC population from five bone marrow sites in the porcine model. In addition, we assessed the feasibility of a commercially available platelet concentrator (Magellan® MAR01™ Arteriocyte Medical Systems, Hopkinton, MA) as a bedside stem cell concentration device. Methods. Analyses of bone marrow aspirate (BMA) and concentrated bone marrow aspirate (cBMA) included bone marrow volume, platelet and nucleated cell yield, colony-forming unit fibroblast (CFU-F) number, flow cytometry, and assessment of differentiation potential...
2017: Stem Cells International
https://www.readbyqxmd.com/read/28533428/gps-urge-bma-to-explore-copayments-for-some-services
#8
Gareth Iacobucci
No abstract text is available yet for this article.
May 22, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28526699/tory-plan-to-double-migrant-worker-surcharge-will-worsen-nhs-staffing-crisis-says-bma
#9
Matthew Limb
No abstract text is available yet for this article.
May 19, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28526677/world-medical-association-rejects-bma-request-to-suspend-president
#10
Zosia Kmietowicz
No abstract text is available yet for this article.
May 19, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28498668/kinetics-of-the-reactions-of-no3-radical-with-methacrylate-esters
#11
Li Zhou, A R Ravishankara, Steven S Brown, Mahmoud Idir, Kyle J Zarzana, Véronique Daële, Abdelwahid Mellouki
Two different experimental methods (relative rate and absolute rate methods) were used to measure the rate coefficients for the reactions of NO3 radical with six methacrylate esters: methyl methacrylate (MMA, k1), ethyl methacrylate (EMA, k2), propyl methacrylate (PMA, k3), isopropyl methacrylate (IPMA, k4), butyl methacrylate (BMA, k5), and isobutyl methacrylate (IBMA, k6). In the relative rate method, the loss of the esters relative to that of a reference compound was followed in a 7300 L Teflon-walled chamber at 298 ± 2 K and 1000 ± 5 hpa...
June 15, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28495820/next-government-must-tackle-public-health-ticking-time-bomb-says-bma
#12
Jacqui Wise
No abstract text is available yet for this article.
May 11, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28482561/laser-assisted-triggered-drug-release-from-silver-nanoparticles-grafted-dual-responsive-polymer
#13
Mitra Amoli-Diva, Rasoul Sadighi-Bonabi, Kamyar Pourghazi
Laser assisted drug release from a synthesized plain polymer composed of poly (butyl methacrylate-co-acrylamide-co-methacrylic acid) [P(BMA-co-AAm-co-MAA)] and a metallo-polymer composed of silver nanoparticles (Ag NPs) grafted plain polymer (the nanocomposite) were studied to investigate their capability to serve as drug carriers. Positive temperature dependent swelling changes were observed for both carriers and their thermal sensitivity and thermal and optical switching properties were investigated in two buffered solutions...
July 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28465290/nhs-must-be-an-election-priority-says-bma-chair
#14
Abi Rimmer
No abstract text is available yet for this article.
May 2, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28464015/forecasting-influenza-in-hong-kong-with-google-search-queries-and-statistical-model-fusion
#15
Qinneng Xu, Yulia R Gel, L Leticia Ramirez Ramirez, Kusha Nezafati, Qingpeng Zhang, Kwok-Leung Tsui
BACKGROUND: The objective of this study is to investigate predictive utility of online social media and web search queries, particularly, Google search data, to forecast new cases of influenza-like-illness (ILI) in general outpatient clinics (GOPC) in Hong Kong. To mitigate the impact of sensitivity to self-excitement (i.e., fickle media interest) and other artifacts of online social media data, in our approach we fuse multiple offline and online data sources. METHODS: Four individual models: generalized linear model (GLM), least absolute shrinkage and selection operator (LASSO), autoregressive integrated moving average (ARIMA), and deep learning (DL) with Feedforward Neural Networks (FNN) are employed to forecast ILI-GOPC both one week and two weeks in advance...
2017: PloS One
https://www.readbyqxmd.com/read/28463052/preparation-and-oil-absorbency-of-kapok-g-butyl-methacrylate
#16
Jintao Wang, Yian Zheng, Aiqin Wang
Butyl methacrylate (BMA) was grafted onto kapok fiber using benzoyl peroxide (BPO) as initiator. The structure of the grafted kapok was investigated using Fourier transform infrared spectroscopy and scanning electron microscopy. The results illustrated that BMA was successfully grafted onto the kapok fiber surface. The effects of monomer concentration, temperature and time on the oil absorbency of grafted kapok fiber were investigated. The oil absorbencies of raw kapok, NaClO2-treated kapok fiber and kapok-g-butyl methacrylate were evaluated and compared...
May 5, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28461234/studies-on-the-contributions-of-smoke-constituents-individually-and-in-mixtures-in-a-range-of-in-vitro-bioactivity-assays
#17
Regina Stabbert, Ruth Dempsey, Joerg Diekmann, Christian Euchenhofer, Timo Hagemeister, Hans-Juergen Haussmann, Arno Knorr, Boris P Mueller, Pavel Pospisil, Wolf Reininghaus, Ewald Roemer, Franz J Tewes, Detlef J Veltel
Tobacco smoke is a complex mixture with over 8700 identified constituents. Smoking causes many diseases including lung cancer, cardiovascular disease, and chronic obstructive pulmonary disease. However, the mechanisms of how cigarette smoke impacts disease initiation or progression are not well understood and individual smoke constituents causing these effects are not generally agreed upon. The studies reported here were part of a series of investigations into the contributions of selected smoke constituents to the biological activity of cigarette smoke...
April 28, 2017: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/28442487/delays-in-gp-rescue-package-are-unacceptable-says-bma
#18
Gareth Iacobucci
No abstract text is available yet for this article.
April 25, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28434382/the-bma-patient-information-awards-what-s-the-history
#19
Carly Dakin
The British Medical Association (BMA) Patient Information Awards has been running since 1997. This article briefly looks back at it's history and origins.
January 2017: Journal of Visual Communication in Medicine
https://www.readbyqxmd.com/read/28417528/attribution-of-seasonal-leaf-area-index-trends-in-the-northern-latitudes-with-optimally-integrated-ecosystem-models
#20
Zaichun Zhu, Shilong Piao, Xu Lian, Ranga B Myneni, Shushi Peng, Hui Yang
Significant increases in remotely sensed vegetation indices in the northern latitudes since the 1980s have been detected and attributed at annual and growing season scales. However, we presently lack a systematic understanding of how vegetation responds to asymmetric seasonal environmental changes. In this study, we first investigated trends in the seasonal mean leaf area index (LAI) at northern latitudes (north of 30°N) between 1982 and 2009 using three remotely sensed long-term LAI data sets. The most significant LAI increases occurred in summer (0...
April 17, 2017: Global Change Biology
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