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https://www.readbyqxmd.com/read/28710477/rna-structure-refinement-using-nmr-solvent-accessibility-data
#1
Christoph Hartlmüller, Johannes C Günther, Antje C Wolter, Jens Wöhnert, Michael Sattler, Tobias Madl
NMR spectroscopy is a powerful technique to study ribonucleic acids (RNAs) which are key players in a plethora of cellular processes. Although the NMR toolbox for structural studies of RNAs expanded during the last decades, they often remain challenging. Here, we show that solvent paramagnetic relaxation enhancements (sPRE) induced by the soluble, paramagnetic compound Gd(DTPA-BMA) provide a quantitative measure for RNA solvent accessibility and encode distance-to-surface information that correlates well with RNA structure and improves accuracy and convergence of RNA structure determination...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28706388/comparison-of-bone-marrow-aspiration-cytology-with-bone-marrow-trephine-biopsy-histopathology-an-observational-study
#2
Meenu Gilotra, Monika Gupta, Sunita Singh, Rajeev Sen
INTRODUCTION: Bone marrow examination is a useful investigative tool for the diagnosis of many hematological and nonhematological disorders. Bone marrow aspiration (BMA) provides information about the numerical and cytological features of marrow cells, whereas bone marrow trephine biopsies (BMB) provide excellent appreciation of spatial relationships between cells and of overall bone marrow structure. We conducted this study with the objective of comparing the accuracy of BMA with BMB in the diagnosis of various hematological disorders...
July 2017: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/28700969/solubilization-of-poorly-water-soluble-compounds-using-amphiphilic-phospholipid-polymers-with-different-molecular-architectures
#3
Mingwei Mu, Tomohiro Konno, Yuuki Inoue, Kazuhiko Ishihara
To achieve stable and effective solubilization of poorly water-soluble bioactive compounds, water-soluble and amphiphilic polymers composed of hydrophilic 2-methacryloyloxyethyl phosphorylcholine (MPC) units and hydrophobic n-butyl methacrylate (BMA) units were prepared. MPC polymers having different molecular architectures, such as random-type monomer unit sequences and block-type sequences, formed polymer aggregates when they were dissolved in aqueous media. The structure of the random-type polymer aggregate was loose and flexible...
June 29, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28687560/unsustainable-pressure-on-gps-has-led-to-dip-in-patient-satisfaction-says-bma
#4
Abi Rimmer
No abstract text is available yet for this article.
July 7, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28670519/synthesis-and-characterization-of-pmbn-as-a-biocompatible-nanopolymer-for-bio-applications
#5
Puria Motamed Fath, Fatemeh Yazdian, Rogayyeh Jamjah, Bahman Ebrahimi Hosseinzadeh, Maede Rahimnezhad, Razi Sahraeian, Ashrafalsadat Hatamian
OBJECTIVE: Poly [2-methacryloyloxyethyl phosphoryl choline (MPC)-co-n-buthyl methacrylate (BMA)-co-p-nitrophenyl-oxycrabonyl poly ethylene glycol-methacrylate (ME- ONP)] (PMBN), a biocompatible terpolymer, is a unique polymer with applications that range from drug delivery systems (DDS) to scaffolds and biomedical devices. In this research, we have prepared a monomer of p-nitrophenyl-oxycarbonyl poly (ethylene glycol) methacrylate (MEONP) to synthesize this polymer. Next, we designed and prepared a smart, water soluble, amphiphilic PMBN polymer composed of MPC, BMA, and MEONP...
July 2017: Cell Journal
https://www.readbyqxmd.com/read/28667072/bma-annual-meeting-senior-trainees-will-be-balloted-on-new-consultant-contract-says-bma
#6
Tom Moberly
No abstract text is available yet for this article.
June 30, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28663281/bma-annual-meeting-pregabalin-must-be-made-a-controlled-drug-bma-says
#7
Tom Moberly
No abstract text is available yet for this article.
June 29, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28663206/bma-annual-meeting-one-in-10-doctors-have-european-colleagues-who-have-left-the-uk-because-of-brexit-says-bma
#8
Abi Rimmer
No abstract text is available yet for this article.
June 29, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28663188/bma-annual-meeting-stps-should-be-abandoned-says-bma
#9
Abi Rimmer
No abstract text is available yet for this article.
June 29, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28659286/bma-annual-meeting-doctors-who-carry-out-abortions-should-not-face-criminal-sanctions-says-bma
#10
Abi Rimmer, Rebecca Coombes
No abstract text is available yet for this article.
June 28, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28659265/bma-annual-meeting-department-of-health-must-stop-sharing-patient-details-with-immigration-enforcers-says-bma
#11
Abi Rimmer
No abstract text is available yet for this article.
June 28, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28659260/bma-annual-meeting-gps-working-at-unsafe-levels-should-issue-black-alert-style-warnings-says-bma
#12
Abi Rimmer
No abstract text is available yet for this article.
June 28, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28655851/bma-annual-meeting-social-media-abuse-leads-to-new-bma-code-of-conduct
#13
Rebecca Coombes
No abstract text is available yet for this article.
June 27, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28655833/bma-annual-meeting-the-bma-will-lobby-for-the-abolition-of-referral-management-systems
#14
Abi Rimmer
No abstract text is available yet for this article.
June 27, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28655747/mark-porter-gives-final-speech-to-bma-annual-meeting
#15
(no author information available yet)
No abstract text is available yet for this article.
June 27, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28655724/bma-annual-meeting-bma-will-work-to-ensure-patients-have-timely-access-to-wheelchairs
#16
Abi Rimmer
No abstract text is available yet for this article.
June 27, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28652897/low-level-laser-therapy-in-russia-history-science-and-practice
#17
REVIEW
Sergey Vladimirovich Moskvin
In Russia (formerly USSR) study of biomodulation action (BMA) mechanisms of low-intensity laser irradiation (LILI) began in 1964, immediately after the development of lasers. During the period from 1965 to 1972 several dozens of scientific conferences were held, hundreds of studies were published. Generally, secondary mechanisms and results of LILI effect on patients with various diseases were studied. This data was immediately implemented into practical medicine in the fields of oncology, surgery, dermatology and dentistry, and since 1974 low level laser therapy (LLLT) is included in the standard of state medical care...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/28652392/bma-annual-meeting-gmc-must-recognise-that-a-lack-of-resources-puts-doctors-at-risk-of-mistakes-says-the-bma
#18
Abi Rimmer
No abstract text is available yet for this article.
June 26, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28652384/bma-annual-meeting-uk-government-must-act-to-avert-future-medical-workforce-crises-says-bma
#19
Abi Rimmer
No abstract text is available yet for this article.
June 26, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28652277/bma-annual-meeting-sending-mental-health-patients-out-of-area-for-treatment-is-endemic-says-bma
#20
Jacqui Wise
No abstract text is available yet for this article.
June 26, 2017: BMJ: British Medical Journal
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