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https://www.readbyqxmd.com/read/29778904/c-lysozyme-contributes-to-antiviral-immunity-in-bombyx-mori-against-nucleopolyhedrovirus-infection
#1
Ting-Ting Chen, Li-Rong Tan, Nan Hu, Zhan-Qi Dong, Zhi-Gang Hu, Ya-Ming Jiang, Peng Chen, Min-Hui Pan, Cheng Lu
Lysozymes is a ubiquitous immune effector that is widely distributed in both vertebrates and invertebrates. Previous reports have shown that lysozymes significantly inhibit viral infections in vertebrates. However, the antiviral effects of lysozymes in invertebrates remain unclear. Here, we investigated the role of lysozymes in Bombyx mori (B. mori) response to viral infection by overexpressing B. mori C-lysozyme (BmC-LZM) in larvae and cells. We found that BmC-LZM was up-regulated in cells in response to viral infection...
May 17, 2018: Journal of Insect Physiology
https://www.readbyqxmd.com/read/29769819/structural-and-biomechanical-adaptations-to-free-fall-landing-in-hindlimb-cortical-bone-of-growing-female-rats
#2
Hsin-Shih Lin, Ho-Seng Wang, Hung-Ta Chiu, Kuang-You B Cheng, Ar-Tyan Hsu, Tsang-Hai Huang
The purpose of the study was to investigate the adaptation process of hindlimb cortical bone subjected to free-fall landing training. Female Wistar rats (7 weeks old) were randomly assigned to four landing (L) groups and four age-matched control (C) groups (n = 12 per group): L1, L2, L4 L8, C1, C2, C4 and C8. Animals in the L1, L2, L4 and L8 groups were respectively subjected to 1, 2, 4 and 8 weeks of free-fall-landing training (40 cm height, 30 times/day and 5 days/week) while the C1, C2, C4 and C8 groups served as age-matched control groups...
June 2018: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29759060/correction-to-overweight-adolescents-views-on-physical-activity-experiences-of-participants-in-an-internet-based-intervention-a-qualitative-study
#3
Turid Kristin Bigum Sundar, Knut Løndal, Per Lagerløv, Kari Glavin, Sølvi Helseth
Correction to: BMC Public Health (2018) 18: 448. https://doi.org/10.1186/s12889-018-5324-x . In the original version of this article [1], published on 4 April 2018, there was 1 incorrect author family name. The redundant affiliation (5) has also been removed. The original article has been updated.
May 14, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29758361/bone-accrual-in-oligo-amenorrheic-athletes-eumenorrheic-athletes-and-non-athletes
#4
Vibha Singhal, Karen Campoverde Reyes, Brooke Pfister, Kathryn Ackerman, Meghan Slattery, Katherine Cooper, Alexander Toth, Nupur Gupta, Mark Goldstein, Kamryn Eddy, Madhusmita Misra
BACKGROUND: Mechanical loading improves bone mineral density (BMD) and strength while decreasing fracture risk. Cross-sectional studies show that exercise advantage is lost in oligo-amenorrheic athletes (OA). Longitudinal studies examining the opposing effects of exercise and hypogonadism on bone are lacking in adolescents/young adults. OBJECTIVE: Evaluate differences in bone accrual over 12 months in OA, eumenorrheic athletes (EA) and non-athletes (NA). We hypothesized that bone accrual would be lower in OA than EA and NA, with differences most pronounced at non-weight bearing trabecular sites...
May 11, 2018: Bone
https://www.readbyqxmd.com/read/29756977/effects-of-red-wine-grape-juice-and-resveratrol-consumption-on-bone-parameters-of-wistar-rats-submitted-to-high-fat-diet-and-physical-training
#5
Letícia Monteiro da Fonseca Cardoso, Nina Da Matta Alvarez Pimenta, Raiza Da Silva Ferreira Fiochi, Bruna Ferreira Mota Mota, Juliana Arruda de Souza Monnerat, Cristiane Correia Teixeira, Renata Beatriz Da Rocha Ramalho, Isabelle Waleska Maldronato, Manuela Dolisnky, Gilson Teles Boaventura, Vilma Blondet, Sergio Girão Barroso, Carlos Alberto Soares da Costa, Gabrielle De Souza Rocha
INTRODUCTION: intake of diets with high saturated fat may produce deleterious effects on bone mineralization. Lifestyle changes help reduce the bone loss observed in osteoporosis. Resveratrol, present in grape juice and red wine, has osteogenic and osteoinductive effects, being potentially beneficial for bone health. OBJECTIVE: to evaluate the effects of red grape juice, red wine and resveratrol consumption on bone parameters in Wistar rats submitted to a high-fat diet and physical training...
October 27, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29743660/functional-indicators-of-vitamin-d-adequacy-for-very-low-birth-weight-infants
#6
Sarah N Taylor, Amy Wahlquist, Carol L Wagner, Viswanathan Ramakrishnan, Myla Ebeling, Bruce W Hollis
OBJECTIVE: To identify the vitamin D status to optimize calcium and bone health in preterm infants. STUDY DESIGN: Very low birth weight infants had measurement of 25-hydroxyvitamin D status and markers of calcium and bone health from birth to term age. Piecewise linear regression modeling was performed to identify a 25-hydroxyvitamin D threshold associated with stable parathyroid hormone concentration and bone mineralization. RESULTS: In a cohort of 89 infants at term age, femur BMC and density increased linearly with 25-hydroxyvitamin D status until reaching a threshold of 48 ng/mL and 46 ng/mL, respectively...
May 9, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29737414/bone-geometry-in-young-male-and-female-football-players-a-peripheral-quantitative-computed-tomography-pqct-study
#7
Gabriel Lozano-Berges, Ángel Matute-Llorente, Alejandro Gómez-Bruton, Alex González-Agüero, Germán Vicente-Rodríguez, José A Casajús
The present study shows that football practice during growth may improve bone geometry in male and female football players. However, only females had better bone strength in comparison with controls. PURPOSE: The aim of this study was to compare bone geometry in adolescent football players and controls. METHODS: A total of 107 football players (71 males/36 females; mean age 12.7 ± 0.6/12.7 ± 0.6 years) and 42 controls (20 males/22 females; mean age 13...
May 8, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29734464/low-muscle-strength-and-mass-is-associated-with-the-accelerated-decline-of-bone-microarchitecture-at-the-distal-radius-in-older-men-the-prospective-strambo-study
#8
Philippe Wagner, Roland Chapurlat, René Ecochard, Pawel Szulc
Low muscle mass and strength are associated with poor bone microarchitecture. We studied the association of muscle mass and strength with changes in bone microarchitecture of distal radius in 821 older men during an 8-year prospective follow-up. Bone microarchitecture was assessed by high resolution peripheral quantitative computed tomography (XtremeCT-1, Scanco) at baseline, then after 4 and 8 years. Relative appendicular lean mass of the upper limbs (RALM-u.l.) was calculated as DXA-measured lean mass of upper limbs divided by (height)2 ...
May 7, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29728090/what-can-we-learn-from-problem-based-learning-tutors-at-a-graduate-entry-medical-school-a-mixed-method-approach
#9
Diane O Doherty, Helena Mc Keague, Sarah Harney, Gerard Browne, Deirdre McGrath
Problem-based learning (PBL) has been adopted by many medical schools as an innovative method to deliver an integrated medical curriculum since its inception at McMaster University (Dornan et al., Med Educ 39(2):163-170, 2005; Finucane et al., Med Educ 35(1):56-61, 2001; Barrows, Tutorials in problem-based learning: A new direction in teaching the health professions, 1984). The student experience in PBL has been explored in detail (Merriam, New Directions for Adult and Continuing Education 89: 3-13, 2001; Azer, Kaohsiung J Med Sci 25(5): 240-249, 2009; Boelens et al...
May 4, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29726227/-environmental-selection-and-dispersal-limitation-drive-the-assemblage-of-bacterial-community-in-temperate-forest-soils
#10
Zhuan Zhuan Ma, Sha Sha Qiao, Miao Wen Cao, Yong Na Zhou, Jin Xian Liu, Tong Jia, Cui Li, Bao Feng Chai
Environmental selection and dispersal limitation are two basic processes underlying community assembly. The relative importance of those two processes differs across scales, community identities, and community types. The processes responsible for structuring microbial communities in soil of temperate subalpine forest are poorly understood. Here, we investigated the relationship between soil bacterial community structure and environmental factors, and quantified the relative role of edaphic factors, vegetation, and spatial variables in shaping the structure of six soil bacterial communities (LpMC1, LpMC2, PwMC, PmMC, PtMC, and BMC) in five forest types including Larix principis-rupprechtii, Picea wilsonii, Picea meyeri, Pinus tabulaeformis, and Betula platyphylla in Pangquangou Nature Reserve by using PCR-DGGE technology...
April 2018: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://www.readbyqxmd.com/read/29722809/repeatability-and-reproducibility-of-measurements-obtained-by-dual-energy-x-ray-absorptiometry-on-pig-carcasses
#11
M Kipper, M Marcoux, I Andretta, C Pomar
The precision of a dual-energy X-ray absorptiometry (DXA) device in terms of repeatability and reproducibility was evaluated on nine left half-carcasses from pigs with large variability in body weight and fat content. Repeatability was assessed by scanning each carcass 10 times sequentially in the same position. Reproducibility was assessed by scanning each carcass in 10 different positions. Images were analyzed with DXA software using a custom region of interest (ROI) and the standard head, trunk, arm, and leg ROI...
May 2, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29721489/the-brotherhood-medical-center-collaborative-foundation-of-maternity-and-children-s-healthcare-facility-for-displaced-syrians
#12
Rahma Aburas, Amina Najeeb, Laila Baageel, Tim K Mackey
The United Nations has declared the Syrian conflict, with more than 50% of Syria's population currently displaced, as the worst humanitarian crisis of the twenty-first century. The Syrian conflict has led to a collapse of infrastructure, including access to critical and lifesaving healthcare services. Women and children account for approximately 75% of internally displaced Syrians and refugees. This population is also particularly vulnerable to poor health outcomes, a condition worsened by lack of access to maternal and child health services...
2018: Frontiers in Public Health
https://www.readbyqxmd.com/read/29713797/whole-egg-consumption-and-cortical-bone-in-healthy-children
#13
L M Coheley, J M Kindler, E M Laing, A Oshri, K M Hill Gallant, S J Warden, M Peacock, C M Weaver, R D Lewis
Eggs contain bioactive compounds thought to benefit pediatric bone. This cross-sectional study shows a positive link between childhood egg intake and radius cortical bone. If randomized trials confirm our findings, incorporating eggs into children's diets could have a significant impact in preventing childhood fractures and reducing the risk of osteoporosis. INTRODUCTION: This study examined the relationships between egg consumption and cortical bone in children. METHODS: The cross-sectional study design included 294 9-13-year-old black and white males and females...
April 30, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29710518/the-higher-osteoprotective-activity-of-psoralidin-in-vivo-than-coumestrol-is-attributed-by-its-presence-of-an-isopentenyl-group-and-through-activated-pi3k-akt-axis
#14
Yuankun Zhai, Qingfeng Wang, Yingying Li, Jiawei Cui, Kun Feng, Xijian Kong, Cory J Xian
Prenylation of bioactive natural compounds has been postulated to be able to enhance the utilization rate and affinity of the compounds with cell membranes, thus promote their bioactivities. Coumestrol, isolated from Medicago sativa, has been known as a phytoestrogen which has bone health benefits. In our previous work, psoralidin, a prenylated coumestrol, was proved to have a higher ability than coumestrol to promote bone formation and to attenuate resorption in vitro. However, it remains to be investigated whether psoralidin will have stronger bone health benefits than coumestrol...
April 3, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29708436/prolactin-levels-do-not-rise-among-transgender-women-treated-with-estradiol-and-spironolactone
#15
Jason R Bisson, Kelly J Chan, Joshua D Safer
CONTEXT: Existing transgender treatment guidelines suggest that for transfeminine hormone treatment there is a need to monitor prolactin levels. Also, recent studies suggest that use of cyproterone acetate as an adjunctive anti-androgen during transgender hormone treatment may elevate serum prolactin. OBJECTIVE: We sought to determine whether the reported relationship between transfeminine estradiol treatment and hyperprolactinemia would be evident when the regimen used spironolactone as the adjunctive anti-androgen...
April 30, 2018: Endocrine Practice
https://www.readbyqxmd.com/read/29707398/severe-bilateral-breast-mucinous-carcinoma-with-bilateral-lungs-and-cutaneous-metastasis-a-case-report-and-literature-review
#16
Rong Pu, Yanchu Li, Xianyong Li
The case of a female who had severe, rare, terminal breast mucinous carcinoma (BMC) and failed to receive surgery and chemotherapy was reported. The patient was diagnosed with pure BMC (ER++, PR++, CerbB-2-, and Ki-67 10%) accompanied with bilateral lungs, bilateral chest walls with skin ulcer ( D  = 14 cm), lymph nodes of bilateral armpits, and right supraclavicular metastases. ECOG (Eastern Cooperative Oncology Group) and NRS (Numeric Rating Scale) pain scores were 4 and 6, respectively. Because the patient refused traditional chemotherapy and radiotherapy on religious grounds, an herbal medicine containing Panax ginseng , Agrimonia pilosa , and white flower Patrinia herb was administered; extensive nursing for tumor debridement was also provided...
2018: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/29703197/phylogenomics-resolves-the-evolutionary-chronicle-of-our-squirting-closest-relatives
#17
Gonzalo Giribet
A recent paper in BMC Biology has resolved the family relationships of sea squirts, one of our closest invertebrate relatives, by using a large phylogenomic data set derived from available genomes and newly generated transcriptomes. The work confirms previous ideas that ascidians (the sea squirts) are not monophyletic, as they include some pelagic jelly-like relatives, and proposes a chronogram for a group that has been difficult to resolve due to their accelerated genome evolution.See research article: https://bmcbiol...
April 27, 2018: BMC Biology
https://www.readbyqxmd.com/read/29688463/influence-of-gait-on-bone-strength-in-turkeys-with-leg-defects
#18
E O Oviedo-Rondón, P L Mente, C Arellano, B D X Lascelles, A Mitchell
Leg problems have become more frequent in fast-growing turkeys. The objective of this study was to evaluate the effects of common leg defects on kinetic parameters of gait and biomechanical properties of bone. Nine hundred, day-old, male, Large White turkeys were raised in 48 floor pens. At 42 d of age, turkeys were divided into four categories of leg condition as determined by visual evaluation: Normal, Crooked toes, Shaky legs, and Valgus. Fifteen toms were selected from each group and trained to walk on a pressure sensitive walkway...
April 23, 2018: Poultry Science
https://www.readbyqxmd.com/read/29681438/usefulness-of-reflection-scanning-in-determining-whole-body-composition-in-broadly-built-individuals-using-dual-energy-x-ray-absorptiometry
#19
Andreia V Moço, Catarina N Matias, Diana A Santos, Paulo M Rocha, Cláudia S Minderico, Edilson S Cyrino, Luís B Sardinha, Analiza M Silva
Whole-body composition analysis by dual-energy X-ray absorptiometry (DXA) requires subjects to fit within the width limits of the DXA bed. To overcome this limitation, the aim of this study was to validate a partial scanning technique at which the upper left limb is deliberately left unscanned and measurements are "reflected" from the right-side upper limb. A Hologic Explorer-W densitometer was used in a sample of 189 participants, including athletes and nonathletes, ranging from underweight to obese (body mass index: 17...
March 27, 2018: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/29679731/changes-in-pediatric-dxa-measures-of-musculoskeletal-outcomes-and-correlation-with-quantitative-ct-following-treatment-of-acute-lymphoblastic-leukemia
#20
Sogol Mostoufi-Moab, Andrea Kelly, Jonathan A Mitchell, Joshua Baker, Babette S Zemel, Jill Brodsky, Jin Long, Mary B Leonard
We previously reported significant gains in pQCT measures of tibia trabecular bone mineral density (BMD) and cortical structure following completion of therapy in children and adolescents with acute lymphoblastic leukemia (ALL). The objective of this study was to examine changes in DXA measures used in clinical practice and expressed as Z-scores using robust national reference data. Children and adolescents, ages 5 to 18 years were enrolled within 2 (median 0.8) years of completing ALL therapy. DXA total-body less-head bone mineral content (TBLH-BMC), and spine, total hip, femoral neck, and 1/3rd radius areal BMD (aBMD) were assessed in 45 participants at enrollment and 12-months later...
April 18, 2018: Bone
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