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https://www.readbyqxmd.com/read/29346609/decreased-serum-levels-of-ghrelin-and-brain-derived-neurotrophic-factor-in-premenopausal-women-with-metabolic-syndrome
#1
Masoumeh Jabbari, Sorayya Kheirouri, Mohammad Alizadeh
Objective: We aimed to investigate the association between serum levels of ghrelin and brain-derived neurotrophic factor (BDNF) with MetS and its components in premenopausal women. Methods: 43 patients with MetS and 43 healthy controls participated in this study. Participants' body mass index (BMI), waist circumference (WC), systolic and diastolic blood pressure (SBP and DBP) were measured. Serum levels of total cholesterol (TC), triglyceride (TG), low and high density lipoprotein cholesterol (LDL-C and HDL-C), fasting blood sugar (FBS), insulin, BDNF and ghrelin determined...
January 12, 2018: Laboratory Medicine
https://www.readbyqxmd.com/read/29343931/effect-of-modified-slow-breathing-exercise-on-perceived-stress-and-basal-cardiovascular-parameters
#2
G Sunil Naik, G S Gaur, G K Pal
Context: Different types of breathing exercises have varied effects on cardiovascular parameters and the stress levels in an individual. Aim: The aim of this study was to assess the effect of a modified form of isolated alternate nostril, slow breathing exercise on perceived stress, and cardiovascular parameters in young, male volunteers. Settings and Design: This was a randomized control study carried out at Advanced Centre for Yoga Therapy Education and Research, Department of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry in 2014...
January 2018: International Journal of Yoga
https://www.readbyqxmd.com/read/29340500/respiratory-evaluation-through-volumetric-capnography-among-grade-iii-obese-and-eutrophic-individuals-a-comparative-study
#3
Débora Aparecida Oliveira Modena, Marcos Mello Moreira, Ilma Aparecida Paschoal, Mônica Corso Pereira, Luiz Cláudio Martins, Everton Cazzo, Elinton Adami Chaim
BACKGROUND: Excess trunk body fat in obese individuals influences respiratory physiological function. The aims of this study were to compare volumetric capnography findings (VCap) between severely obese patients and normal-weight subjects and to assess whether there is any association between neck circumference (NC), waist-hip ratio (WHR) and VCap among grade III obese individuals. DESIGN AND SETTING: Analytical observational case-matched cross-sectional study, University of Campinas...
January 15, 2018: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/29336626/antihypertensive-monotherapy-or-combined-therapy-which-is-more-effective-on-functional-status
#4
Liliana C Baptista, André Pinto Amorim, João Valente-Dos-Santos, Aristides M Machado-Rodrigues, Manuel Teixeira Veríssimo, Raul A Martins
BACKGROUND: This study aims to analyze the effects of anti-hypertensive monotherapy and combined therapy on functional status, and cardiovascular risk outcomes in older adults. METHODS: This longitudinal non-randomized cohort study, involved hypertensive older adults (n = 440) aged 60 or more years with comorbidities. Participants underwent a community exercise training program and one of the following 2 conditions: i) use of daily mono-dose angiotensin-converting enzyme inhibitors (ACEi; n= 232); ii) combined therapy including ACEi plus other class agent (Combined; n= 208)...
January 16, 2018: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/29335400/causal-associations-between-risk-factors-and-common-diseases-inferred-from-gwas-summary-data
#5
Zhihong Zhu, Zhili Zheng, Futao Zhang, Yang Wu, Maciej Trzaskowski, Robert Maier, Matthew R Robinson, John J McGrath, Peter M Visscher, Naomi R Wray, Jian Yang
Health risk factors such as body mass index (BMI) and serum cholesterol are associated with many common diseases. It often remains unclear whether the risk factors are cause or consequence of disease, or whether the associations are the result of confounding. We develop and apply a method (called GSMR) that performs a multi-SNP Mendelian randomization analysis using summary-level data from genome-wide association studies to test the causal associations of BMI, waist-to-hip ratio, serum cholesterols, blood pressures, height, and years of schooling (EduYears) with common diseases (sample sizes of up to 405,072)...
January 15, 2018: Nature Communications
https://www.readbyqxmd.com/read/29334692/body-mass-index-abdominal-adiposity-weight-gain-and-risk-of-developing-hypertension-a-systematic-review-and-dose-response-meta-analysis-of-more-than-2-3-million-participants
#6
REVIEW
A Jayedi, A Rashidy-Pour, M Khorshidi, S Shab-Bidar
OBJECTIVE: This study aimed to test the association between anthropometric measures and risk of developing hypertension. METHODS: We did a systematic search using PubMed and Scopus, from inception up to January 2017. Prospective cohort studies reporting the risk estimates of hypertension for three or more quantitative categories of indices of general and abdominal adiposity were included. Summary relative risks were calculated using random-effects models. RESULTS: Fifty-seven prospective cohort studies were included...
January 15, 2018: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29332629/psychobiological-stress-in-vital-exhaustion-findings-from-the-men-stress-40-study
#7
Emilou Noser, Susanne Fischer, Jessica Ruppen, Ulrike Ehlert
OBJECTIVE: Despite the increased risk for cardiovascular morbidity associated with vital exhaustion (VE), the underlying pathophysiological mechanisms remain unclear. Allostatic load may constitute the missing link between VE and cardiovascular diseases. The aim of the present study was to investigate whether men with different degrees of VE would differ in terms of allostatic load, chronic stress, and social support. METHODS: The Men Stress 40+ study sample consisted of N=121 apparently healthy men aged 40 to 75years...
February 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29332108/impact-of-body-mass-index-on-high-blood-pressure-among-obese-children-in-the-western-region-of-saudi-arabia
#8
Abdulmoein E Al-Agha, Areej O Mahjoub
To evaluate the impact of body mass index (BMI) on high blood pressure among obese children and adolescents in western region, Saudi Arabia.  Methods: Cross-sectional data were obtained from 306 (female: 140, male: 166) child, between August 2016 and March 2017. A questioner was filled by health professionals at ambulatory pediatric clinic followed by waist-hip circumference, height, weight, and blood pressure measurement. Diastolic blood pressure (DBP) and systolic blood pressure (SBP) were adjusted to gender, height, and age...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29330426/glucose-independent-segmental-phase-angles-from-multi-frequency-bioimpedance-analysis-to-discriminate-diabetes-mellitus
#9
Min-Ho Jun, Soochan Kim, Boncho Ku, JungHee Cho, Kahye Kim, Ho-Ryong Yoo, Jaeuk U Kim
We investigated segmental phase angles (PAs) in the four limbs using a multi-frequency bioimpedance analysis (MF-BIA) technique for noninvasively diagnosing diabetes mellitus. We conducted a meal tolerance test (MTT) for 45 diabetic and 45 control subjects stratified by age, sex and body mass index (BMI). HbA1c and the waist-to-hip-circumference ratio (WHR) were measured before meal intake, and we measured the glucose levels and MF-BIA PAs 5 times for 2 hours after meal intake. We employed a t-test to examine the statistical significance and the area under the curve (AUC) of the receiver operating characteristics (ROC) to test the classification accuracy using segmental PAs at 5, 50, and 250 kHz...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29329778/high-intensity-interval-training-versus-continuous-training-on-physiological-and-metabolic-variables-in-prediabetes-and-type-2-diabetes-a-meta-analysis
#10
REVIEW
Angélica Trevisan De Nardi, Tainara Tolves, Thatiane Larissa Lenzi, Luis Ulisses Signori, Antônio Marcos Vargas da Silva
AIMS: To compare the effects of high-intensity interval training (HIIT) versus moderate-intensity continuous training (MICT) on functional capacity and cardiometabolic markers in individuals prediabetes and type 2 diabetes (T2D). METHODS: The search was performed in PubMed (MEDLINE), EMBASE, PEDro, CENTRAL, Scopus, LILACS database, and Clinical Trials from the inception to July 2017, included randomized clinical trials that compared the use of HIIT and MICT in prediabetes and T2D adults...
January 9, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29325542/visceral-adipose-tissue-and-carotid-intima-media-thickness-in-hiv-infected-patients-undergoing-cart-a-prospective-cohort-study
#11
Maria Teresa Beires, André Silva-Pinto, Ana Cristina Santos, António José Madureira, Jorge Pereira, Davide Carvalho, António Sarmento, Paula Freitas
BACKGROUND: Combined antiretroviral therapy (cART) in HIV-infected patients has been associated with lipodystrophy, metabolic abnormalities, and an increased risk of cardiovascular disease. Ultrasound measures of carotid artery intima-media thickness (cIMT) have been used as a valid measure of subclinical atherosclerosis and as a tool to predict the risk of cardiovascular events. Our aim was to evaluate the progression of cIMT in HIV-infected patients subjected to cART, with and without lipodystrophy, over a one-year period...
January 11, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29324787/association-of-sex-hormones-with-physical-laboratory-and-imaging-markers-of-anthropometry-in-men-and-women-from-the-general-population
#12
Tom Seyfart, Nele Friedrich, Hanna Kische, Robin Bülow, Henri Wallaschofski, Henry Völzke, Matthias Nauck, Brian G Keevil, Robin Haring
OBJECTIVES: The aim of this study was to evaluate the association of sex hormones with anthropometry in a large population-based cohort, with liquid chromatography-mass spectrometry (LCMS)-based sex hormone measurements and imaging markers. STUDY DESIGN/MAIN OUTCOME MEASURES: Cross-sectional data from 957 men and women from the population-based Study of Health in Pomerania (SHIP) were used. Associations of a comprehensive panel of LCMS-measured sex hormones with anthropometric parameters, laboratory, and imaging markers were analyzed in multivariable regression models for the full sample and stratified by sex...
2018: PloS One
https://www.readbyqxmd.com/read/29324776/effect-of-a-lifestyle-intervention-in-obese-infertile-women-on-cardiometabolic-health-and-quality-of-life-a-randomized-controlled-trial
#13
Lotte van Dammen, Vincent Wekker, Anne M van Oers, Meike A Q Mutsaerts, Rebecca C Painter, Aeilko H Zwinderman, Henk Groen, Cornelieke van de Beek, Anneke C Muller Kobold, Walter K H Kuchenbecker, Ron van Golde, Gerrit J E Oosterhuis, Niels E A Vogel, Ben Willem J Mol, Tessa J Roseboom, Annemieke Hoek
BACKGROUND: The prevalence of obesity, an important cardiometabolic risk factor, is rising in women. Lifestyle improvements are the first step in treatment of obesity, but the success depends on factors like timing and motivation. Women are especially receptive to advice about lifestyle before and during pregnancy. Therefore, we hypothesize that the pre-pregnancy period provides the perfect window of opportunity to improve cardiometabolic health and quality of life of obese infertile women, by means of a lifestyle intervention...
2018: PloS One
https://www.readbyqxmd.com/read/29321674/body-mass-index-waist-circumference-and-waist-to-height-ratio-for-prediction-of-multiple-metabolic-risk-factors-in-chinese-elderly-population
#14
Zhan Gu, Dong Li, Huayu He, Jianying Wang, Xiaojuan Hu, Peihua Zhang, Yanlong Hong, Baocheng Liu, Lei Zhang, Guang Ji
The purpose of this study was to compare the predictive ability of five obesity indices, including body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), waist-to-hip ratio (WHpR) and body adiposity index (BAI), to predict multiple non-adipose metabolic risk factors, including elevated blood pressure (BP), elevated fasting plasma glucose (FPG), elevated triglyceride (TG), reduced high-density lipoprotein cholesterol (HDL-C), elevated serum uric acid (SUA) and non-alcoholic fatty liver disease (NAFLD), in an elderly Chinese population...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29317958/relationship-between-angiopoietin-like-protein-8-and-fasting-serum-triglyceride-level
#15
Hodaka Yamada, Ikuyo Kusaka, Rika Saikawa, Kazuo Hara, Masafumi Kakei, San-E Ishikawa
Background: The aim of the study was to evaluate the correlation between angiopoietin-like protein 8 (ANGPTL8) and metabolic parameters in non-diabetic healthy humans. Methods: We enrolled 30 healthy Japanese adults (25 men and five women). After 9 h of fasting, we collected blood samples and analyzed the ANGPTL8, lipoprotein lipase (LPL), plasma lipid and glucose metabolic parameters. In addition, we performed 75-g oral glucose tolerance test (OGTT) and measured adipokines (tumor necrosis factor-α, leptin and adiponectin)...
February 2018: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29316799/leptin-adiponectin-ratio-in-overweight-patients-gender-differences
#16
Selthofer-Relatić K, Radić R, Stupin A, Šišljagić V, Bošnjak I, Bulj N, Selthofer R, Delić Brkljačić D
OBJECTIVE: Obesity-related atherosclerosis is a systemic disease with a background connected to multiple metabolic-neurohumoral pathways. The leptin/adiponectin ratio has been suggested as an atherosclerotic marker in obese patients. The aim of this study was to assess (1) the significance of the L/A ratio in overweight subjects, (2) the relation with anthropometric/metabolic parameters and (3) gender difference. METHOD: The study included 80 adult males and females, overweight, non-diabetic patients...
January 1, 2018: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/29316628/lipoprotein-cholesterol-fractions-in-marginalized-roma-versus-majority-population
#17
Beáta Hubková, Gabriel Bódy, Jana Mašlanková, Anna Birková, Eugen Frišman, Vladimír Kraus, Mária Mareková
The trend of modern clinical biochemistry is to emphasize the composition and the quality of lipoproteins over their quantity. The serum lipoprotein fractions and subfractions were analyzed by the Lipoprint Lipoprotein Subfractions Testing System, the parameters of lipid profile, as total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C) and triacylglycerides (TAG) were determined by an automated selective biochemical analyzer. Our results showed a significantly lower concentration of cholesterol in the LDL fractions 1 and 2 and in the HDL fractions 8 to 10 in Roma compared to the majority population...
January 6, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29315199/a-waist-hip-ratio-surrogate-more-predictive-than-bmi-of-wound-complications-following-pelvic-and-acetabulum-surgery
#18
Todd Jaeblon, Kevin J Perry, Joseph A Kufera
OBJECTIVES: To determine if a novel surrogate of waist hip ratio (WHR) is more predictive of wound complications following pelvis or acetabulum stabilization than BMI, and describe the method of measuring a WHR proxy (WHRp). DESIGN: Retrospective review. SETTING: One Level-1 Trauma Center PATIENTS:: 161 patients following operative repair of pelvis and acetabulum fractures. INTERVENTION: Operative stabilization of a pelvic ring injury or acetabular fracture MAIN OUTCOME MEASUREMENTS:: Infection (pin, superficial, deep), Wound healing complication METHODS:: We retrospectively reviewed 161 subjects following operative repair of pelvic and acetabular fractures...
January 8, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29315019/time-and-intervention-effects-of-daily-almond-intake-on-the-changes-of-lipid-profile-and-body-composition-among-free-living-healthy-adults
#19
Yanan Liu, Hyo-Jeong Hwang, Hyun-Sook Kim, Hyunjin Park
Favorable health benefits of almond have been shown in several previous studies. However, repeated measures, randomized, controlled trials to investigate the changes due to almond intake based on the time effects have not yet been reported. The current study was conducted to evaluate the effects of daily almond intake on changes in body composition and lipid profiles for 20 weeks with four measurements among healthy adults. Participants in the almond group showed favorable changes on blood lipid profiles, including levels of triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and non-high-density lipoprotein (non-HDL-C) after consuming 56 g of almond per day for 20 weeks compared with those at baseline...
January 9, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29313746/comparison-of-calorie-restricted-diet-and-resveratrol-supplementation-on-anthropometric-indices-metabolic-parameters-and-serum-sirtuin-1-levels-in-patients-with-nonalcoholic-fatty-liver-disease-a-randomized-controlled-clinical-trial
#20
Somayyeh Asghari, Mohammad Asghari-Jafarabadi, Mohammad-Hossein Somi, Seyed-Mostafa Ghavami, Maryam Rafraf
OBJECTIVE: There is a promising perspective regarding the potential effect of resveratrol in preventing and treating metabolic disturbances similar to that of calorie restriction. The aim of this study was to evaluate the effects of calorie-restricted (CR) diet on metabolic parameters and then to investigate whether resveratrol supplementation has beneficial effects similar to CR diet in patients with nonalcoholic fatty liver disease (NAFLD). METHODS: This randomized controlled clinical trial was conducted in 90 patients with NAFLD (males and females) aged 20 to 60 years with body mass index (BMI) ranging from 25 to 35 kg/m2...
January 9, 2018: Journal of the American College of Nutrition
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