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https://www.readbyqxmd.com/read/29775746/anthropometric-measurements-and-mortality-in-frail-older-adults
#1
Jonathan F Easton, Christopher R Stephens, Heriberto Román-Sicilia, Matteo Cesari, Mario Ulises Pérez-Zepeda
BACKGROUND: As the number of older adults increases, so does the number of frail older adults. Although anthropometry has been widely used as a way to stratify the overall mortality risk of a person, the significance of these measurements becomes blurred in the case of frail older adults who have changes in body composition. Therefore, the aim of this study is to determine the association of anthropometric measurements (body mass index, knee-adjusted height body mass index, waist-to-hip ratio and calf circumference) with mortality risk in a group of older Mexican adults...
May 15, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29773697/which-anthropometric-measures-best-indicate-type-2-diabetes-among-russian-somali-and-kurdish-origin-migrants-in-finland-a-cross-sectional-study
#2
Natalia Skogberg, Tiina Laatikainen, Annamari Lundqvist, Eero Lilja, Tommi Härkänen, Päivikki Koponen
OBJECTIVES: To compare the performance of body mass index (BMI), waist-to-height ratio (WHtR), waist circumference (WC) and waist-to-hip ratio (WHR) in detecting type 2 diabetes among Russian, Somali and Kurdish (born in Iraq/Iran) origin migrants and Finns. DESIGN AND PARTICIPANTS: Cross-sectional study comparing health examination survey data of Russian, Somali and Kurdish origin migrants (n=917) aged 30-64 years who took part in the Migrant Health and Wellbeing Survey with the general Finnish population in the Health 2011 Survey (n=887)...
May 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29772027/association-between-different-combination-of-measures-for-obesity-and-new-onset-gallstone-disease
#3
Tong Liu, Wanchao Wang, Yannan Ji, Yiming Wang, Xining Liu, Liying Cao, Siqing Liu
BACKGROUND: Body mass index(BMI) is a calculation index of general obesity. Waist circumference(WC) is a measure of body-fat distribution and always used to estimate abdominal obesity. An important trait of general obesity and abdominal obesity is their propensity to coexist. Using one single measure of obesity could not estimate persons at risk for GSD precisely. OBJECTIVES: This study aimed to compare the predictive values of various combination of measures for obesity(BMI, WC, waist to hip ratio) for new-onset GSD...
2018: PloS One
https://www.readbyqxmd.com/read/29769702/fine-mapping-of-98-obesity-loci-in-mexican-children
#4
Hsin Yen Liu, Akram Alyass, Arkan Abadi, Jesus Peralta-Romero, Fernando Suarez, Jaime Gomez-Zamudio, Astride Audirac, Esteban J Parra, Miguel Cruz, David Meyre
BACKGROUND/OBJECTIVES: Mexico has one of the highest prevalence of childhood obesity in the world. Genome-wide association studies (GWAS) for obesity have identified multiple single-nucleotide polymorphisms (SNPs) in populations of European, East Asian, and African descent. The contribution of these loci to obesity in Mexican children is unclear. We assessed the transferability of 98 obesity loci in Mexican children and fine-mapped the association signals. SUBJECTS/METHODS: The study included 405 and 390 Mexican children with normal weight and obesity...
March 12, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29769528/a-joint-view-on-genetic-variants-for-adiposity-differentiates-subtypes-with-distinct-metabolic-implications
#5
Thomas W Winkler, Felix Günther, Simon Höllerer, Martina Zimmermann, Ruth Jf Loos, Zoltán Kutalik, Iris M Heid
The problem of the genetics of related phenotypes is often addressed by analyzing adjusted-model traits, but such traits warrant cautious interpretation. Here, we adopt a joint view of adiposity traits in ~322,154 subjects (GIANT consortium). We classify 159 signals associated with body mass index (BMI), waist-to-hip ratio (WHR), or WHR adjusted for BMI (WHRadjBMI) at P < 5 × 10-8 , into four classes based on the direction of their effects on BMI and WHR. Our classes help differentiate adiposity genetics with respect to anthropometry, fat depots, and metabolic health...
May 16, 2018: Nature Communications
https://www.readbyqxmd.com/read/29769484/prevalence-of-non-alcoholic-fatty-liver-disease-and-its-biochemical-predictors-in-patients-with-type-2-diabetes-mellitus
#6
M A Kabir, M Z Uddin, N I Siddiqui, I H Robi, M S Malek, M S Islam, S Rahman, M S Hossain, S K Mahapatra, M J Alam, F Ahmad, M S Alam, M A Islam
Non-alcoholic fatty liver disease (NAFLD) is emerging as the most common chronic liver condition in the Western world and it is commonly associated with type 2 diabetes mellitus (DM). The aim of this study to determine the prevalence of NAFLD and identify the predisposing factors in type 2 DM patients with NAFLD. Total of 258 patients of type 2 DM were included in this observational study in the Department of Medicine, Mymensingh Medical College Hospital, Mymensingh, Bangladesh from 11th May 2013 to 11th November 2013...
April 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29763369/adipose-y5r-mrna-is-higher-in-obese-than-non-obese-humans-and-is-correlated-with-obesity-parameters
#7
Saimai Chatree, Chantacha Sitticharoon, Pailin Maikaew, Panapat Uawithya, Supornpim Chearskul
Neuropeptide Y is mainly expressed in the central nervous system to regulate food intake via its receptors, Y receptors, and in various peripheral tissues including adipose tissue. The objectives of this study were to compare Y5R mRNA and adipocyte parameters consisting of area, width, height, and perimeter either between obese and non-obese subjects or between subcutaneous and visceral fat as well as to compare between NPY, Y1R, Y2R, and Y5R mRNA expressions in subcutaneous and visceral adipose tissues. In subcutaneous and visceral adipose tissues, Y5R was greater in obese than in non-obese humans (both P < 0...
May 2018: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29760457/global-genetic-differentiation-of-complex-traits-shaped-by-natural-selection-in-humans
#8
Jing Guo, Yang Wu, Zhihong Zhu, Zhili Zheng, Maciej Trzaskowski, Jian Zeng, Matthew R Robinson, Peter M Visscher, Jian Yang
There are mean differences in complex traits among global human populations. We hypothesize that part of the phenotypic differentiation is due to natural selection. To address this hypothesis, we assess the differentiation in allele frequencies of trait-associated SNPs among African, Eastern Asian, and European populations for ten complex traits using data of large sample size (up to ~405,000). We show that SNPs associated with height ([Formula: see text]), waist-to-hip ratio ([Formula: see text]), and schizophrenia ([Formula: see text]) are significantly more differentiated among populations than matched "control" SNPs, suggesting that these trait-associated SNPs have undergone natural selection...
May 14, 2018: Nature Communications
https://www.readbyqxmd.com/read/29758945/a-10-year-follow-up-of-adiposity-and-dementia-in-swedish-adults-aged-70-years-and-older
#9
Ilse A C Arnoldussen, Valter Sundh, Kristoffer Bäckman, Silke Kern, Svante Östling, Kaj Blennow, Henrik Zetterberg, Ingmar Skoog, Amanda J Kiliaan, Deborah R Gustafson
BACKGROUND: Adiposity measured in mid- or late-life and estimated using anthropometric measures such as body mass index (BMI) and waist-to-hip ratio (WHR), or metabolic markers such as blood leptin and adiponectin levels, is associated with late-onset dementia risk. However, during later life, this association may reverse and aging- and dementia-related processes may differentially affect adiposity measures. OBJECTIVE: We explored associations of concurrent BMI, WHR, and blood leptin and high molecular weight adiponectin levels with dementia occurrence...
May 11, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29756970/critical-overview-of-current-anthropometric-methods-in-comparison-with-a-new-index-to-make-early-detection-of-overweight-in-spanish-university-students-the-normalized-weight-adjusted-index
#10
Guillermo Doménech-Asensi, Carlos Gómez-Gallego, Gaspar Ros-Berruezo, Francisco Javier García-Alonso, Manuel Canteras-Jordana
BACKGROUND: overweight and obesity have been increasing, and university students are an important target for prevention programs. Previous studies have reported differences in the diagnosis between different anthropometric methods, so some students can be misclassified depending on the method used. OBJECTIVE: to evaluate the efficacy of different anthropometric methods to detect those university students in a probable status of overweight, including a comparison with a new proposed method, the normalized weight-adjusted index (NWAI)...
March 1, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29755605/the-prevalence-of-osteopenia-and-osteoporosis-among-malaysian-type-2-diabetic-patients-using-quantitative-ultrasound-densitometer
#11
Shaymaa Abdalwahed Abdulameer, Mohanad Naji Sahib, Syed Azhar Syed Sulaiman
Background: Type 2 Diabetes Mellitus (T2DM) and osteoporosis are both chronic conditions and the relationship between them is complex. Objective: The aims of this study were to assess the prevalence of Low Bone Mineral density (LBMD, i.e ., osteopenia and osteoporosis), as well as, the difference and associations between Quantitative Ultrasound Scan (QUS) parameters with socio-demographic data and clinical related data among T2DM in Penang, Malaysia. Method: An observational, cross-sectional study with a convenient sample of 450 T2DM patients were recruited from the outpatient diabetes clinic at Hospital Pulau Pinang (HPP) to measure Bone Mineral Density (BMD) at the heel bone using QUS...
2018: Open Rheumatology Journal
https://www.readbyqxmd.com/read/29755575/waist-hip-ratio-related-genetic-loci-are-associated-with-risk-of-impaired-fasting-glucose-in-chinese-children-a-case-control-study
#12
Qi-Ying Song, Xiang-Rui Meng, Anke Hinney, Jie-Yun Song, Tao Huang, Jun Ma, Hai-Jun Wang
Background: The meta-analyses of genome-wide association studies identified several waist-hip ratio (WHR) related loci in individuals of European ancestry. Since the pattern of fat distribution and the relationship between fat distribution and glucose metabolism disturbance in Chinese are different from those in Europeans, the present study aimed to explore the individual and cumulative effects of WHR-related loci on glycemic phenotypes in Chinese children. Methods: A total of 2030 children were recruited from two independent studies...
2018: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29755414/non-synonymous-single-nucleotide-polymorphisms-and-physical-activity-interactions-on-adiposity-parameters-in-malaysian-adolescents
#13
Nur Lisa Zaharan, Nor Hanisah Muhamad, Muhammad Yazid Jalaludin, Tin Tin Su, Zahurin Mohamed, M N A Mohamed, Hazreen A Majid
Background: Several non-synonymous single-nucleotide polymorphisms (nsSNPs) have been shown to be associated with obesity. Little is known about their associations and interactions with physical activity (PA) in relation to adiposity parameters among adolescents in Malaysia. Methods: We examined whether (a) PA and (b) selected nsSNPs are associated with adiposity parameters and whether PA interacts with these nsSNPs on these outcomes in adolescents from the Malaysian Health and Adolescents Longitudinal Research Team study ( n  = 1,151)...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29752165/hypertension-and-its-correlate-with-general-and-central-adiposity-a-study-among-urban-population-of-delhi
#14
Meenal Dhall, Kshetrimayum Surmala Devi, Nilupher, Urvashi Gupta, Renu Tyagi, Satwanti Kapoor
AIM: Study aims to assess the association of various adiposity markers with blood pressure levels. STUDY DESIGN: The present study was a cross-sectional study conducted in Delhi. A total of 568 (males- 250, females- 318) participants aged 20-55 years were enrolled for the study. RESULT: Mean height (167.35 ± 7.59) and weight (73.76 ± 15.08) was found to be significantly higher in males. Mean values of minimum waist circumference (183...
May 5, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29747638/relations-of-lipid-parameters-other-variables-with-carotid-intima-media-thickness-and-plaque-in-the-general-chinese-adults-an-observational-study
#15
Qingtao Hou, Sheyu Li, Yun Gao, Haoming Tian
BACKGROUND: It has been reported that non-high-density lipoprotein cholesterol (non-HDL-C) and lipid ratios, including total cholesterol (TC) / high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) / HDL-C, are better predictors for atherosclerosis than conventional lipid profiles. However, there have been few studies comparing the predictive values of different lipid parameters for early atherosclerosis. The aim of this study was to determine the relevant factors of carotid intima-media thickness (IMT) and plaque in the general Chinese adults and analyze the predictive values of different lipid parameters for carotid IMT and plaque...
May 10, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29747603/prevalence-of-general-and-abdominal-obesity-in-portugal-comprehensive-results-from-the-national-food-nutrition-and-physical-activity-survey-2015-2016
#16
Andreia Oliveira, Joana Araújo, Milton Severo, Daniela Correia, Elisabete Ramos, Duarte Torres, Carla Lopes
BACKGROUND: This study includes, for the first time, estimates of general and abdominal obesity prevalence for all ages of the Portuguese population, using common standardized methodologies. Results are compared by sex, age groups, educational level and geographical regions. METHODS: Participants were a representative sample of the Portuguese population aged between 3 months and 84 years of age (n = 6553), enrolled in the National Food, Nutrition and Physical Activity Survey, 2015-2016...
May 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29746318/hiv-1-status-is-independently-associated-with-decreased-erectile-function-among-middle-aged-msm-in-the-era-of-combination-antiretroviral-therapy
#17
Maartje Dijkstra, Rik H W van Lunsen, Katherine W Kooij, Udi Davidovich, Rosan A van Zoest, Ferdinand W M N Wit, Maria Prins, Peter Reiss, Maarten F Schim van der Loeff
INTRODUCTION: HIV-1-infected MSM more often experience sexual dysfunctions than the general population. We assessed associations between HIV-1 status and decreased sexual functioning among MSM. METHODS: We used cross-sectional data from 399 HIV-1-infected MSM mostly on combination antiretroviral therapy (cART) and 366 HIV-1-uninfected MSM aged at least 45 years participating in the AGEhIV Cohort Study. The study questionnaire included questions on erectile function, sexual satisfaction, and sexual desire...
June 1, 2018: AIDS
https://www.readbyqxmd.com/read/29745981/evaluation-of-biochemical-endocrine-and-metabolic-biomarkers-for-the-early-diagnosis-of-polycystic-ovary-syndrome-among-non-obese-saudi-women
#18
Maha H Daghestani
OBJECTIVE: To investigate the potential of selected biochemical, endocrine, and metabolic biomarkers for early diagnosis of polycystic ovary syndrome (PCOS) among non-obese women. METHODS: A prospective observational cross-sectional study was conducted at three medical centers in Makkah, Saudi Arabia, between July 15 and September 20, 2017. Eligible participants were non-obese women diagnosed with PCOS according to the Rotterdam criteria (n=44) and non-obese normo-ovulatory women without signs of PCOS (control group; n=44)...
May 10, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29743321/identical-anthropometric-characteristics-of-impaired-fasting-glucose-combined-with-impaired-glucose-tolerance-and-newly-diagnosed-type-2-diabetes-anthropometric-indicators-to-predict-hyperglycaemia-in-a-community-based-prospective-cohort-study-in-southwest
#19
Fang Zhang, Qin Wan, Hongyi Cao, Lizhi Tang, Daigang Li, Qingguo Lü, Zhe Yan, Jing Li, Qiu Yang, Yuwei Zhang, Nanwei Tong
OBJECTIVES: To assess the anthropometric characteristics of normoglycaemic individuals who subsequently developed hyperglycaemia, and to evaluate the validity of these measures to predict prediabetes and diabetes. DESIGN: A community-based prospective cohort study. PARTICIPANTS: In total, 1885 residents with euglycaemia at baseline from six communities were enrolled. SETTING: Sichuan, southwest China. PRIMARY OUTCOME MEASURES: The incidences of prediabetes and diabetes were the primary outcomes...
May 9, 2018: BMJ Open
https://www.readbyqxmd.com/read/29742131/prevalence-of-high-bloodpressure-hyperglycemia-dyslipidemia-metabolic-syndrome-and-their-determinants-in-ethiopia-evidences-from-the-national-ncds-steps-survey-2015
#20
Yeweyenhareg Feleke Gebreyes, Dejuma Yadeta Goshu, Tedla Kebede Geletew, Terefe Gelibo Argefa, Theodros Getachew Zemedu, Kassahun Amenu Lemu, Feyissa Challa Waka, Alemayehu Bekele Mengesha, Fasil Shiferaw Degefu, Atkure Defar Deghebo, Habtamu Teklie Wubie, Mussie Gebremichael Negeri, Tefera Tadele Tesema, Yabetse Girma Tessema, Mulugeta Guta Regassa, Geremew Gonfa Eba, Misrak Getnet Beyene, Kissi Mudie Yesu, Girum Taye Zeleke, Yewondwossen Tadesse Mengistu, Abebe Bekele Belayneh
The prevalence of diabetes, dyslipidemias, and high blood pressure is increasing worldwide especially in low and middle income countries. World Health Organization has emphasized the importance of the assessment of the magnitude of the specific disease in each country. We determined the prevalence and determinant factors of high blood pressure, hyperglycemia, dyslipidemias and metabolic syndrome in Ethiopia. A community based survey was conducted from -April to June 2015 using WHO NCD STEPS instrument version 3...
2018: PloS One
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